Publications

• Mechanisms by which the cystic fibrosis transmembrane conductance regulator may influence SARS-CoV-2 infection and COVID-19 disease severity.
  FASEB J Volume: 37 Page(s): e23220
  11/01/2023 Authors: Tedbury PR; Manfredi C; Degenhardt F; Conway J; Horwath MC; McCracken C; Sorscher AJ; Moreau S; Wright C; Edwards C
• High-throughput screens identify a lipid nanoparticle that preferentially delivers mRNA to human tumors in vivo.
  J Control Release Volume: 357 Page(s): 394 - 403
  05/01/2023 Authors: Huayamares SG; Lokugamage MP; Rab R; Da Silva Sanchez AJ; Kim H; Radmand A; Loughrey D; Lian L; Hou Y; Achyut BR
• Evaluating antitumor activity of Escherichia coli purine nucleoside phosphorylase against head and neck patient-derived xenografts.
  Cancer Rep (Hoboken) Volume: 6 Page(s): e1708
  02/01/2023 Authors: Rab R; Ehrhardt A; Achyut BR; Joshi D; Gilbert-Ross M; Huang C; Floyd K; Borovjagin AV; Parker WB; Sorscher EJ
• Cystic fibrosis precision therapeutics: Emerging considerations.
  Pediatr Pulmonol Volume: 54 Suppl 3 Page(s): S13 - S17
  11/01/2019 Authors: Joshi D; Ehrhardt A; Hong JS; Sorscher EJ
• MOLECULAR STUDIES AND DRUG DEVELOPMENT FOR THE CFTR W1282X VARIANT
  Volume: 52 Page(s): S327 - S327
  09/01/2017 Authors: Manfredi C; Rab A; Molina SA; Joshi D; Hong J; Ehrhardt A; Sorscher EJ
• MOLECULAR ANALYSIS OF THE CFTR W1282X MUTATION
  PEDIATRIC PULMONOLOGY Volume: 51 Page(s): 293 - 294
  10/01/2016 Authors: Manfredi C; Rab A; Joshi D; Wang W; Kirk K; Saltz J; Mense M; Mahiou J; Sorscher EJ; Hong JS
• MODEL SYSTEMS FOR INVESTIGATING MOLECULAR PATHOGENESIS OF RARE CFTR ALLELES
  PEDIATRIC PULMONOLOGY Volume: 51 Page(s): 256 - 257
  10/01/2016 Authors: Rab A; Wen H; Manfredi C; Ehrhardt A; Joshi D; Sorscher EJ; Hong JS
• Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop.
  J Biol Chem Volume: 291 Page(s): 1854 - 1865
  01/22/2016 Authors: Ehrhardt A; Chung WJ; Pyle LC; Wang W; Nowotarski K; Mulvihill CM; Ramjeesingh M; Hong J; Velu SE; Lewis HA
• Absence of M-Ras modulates social behavior in mice.
  BMC Neurosci Volume: 16 Page(s): 68
  10/21/2015 Authors: Ehrhardt A; Wang B; Leung MJ; Schrader JW
• Urinary Retention, Incontinence, and Dysregulation of Muscarinic Receptors in Male Mice Lacking Mras.
  PLoS One Volume: 10 Page(s): e0141493
  01/01/2015 Authors: Ehrhardt A; Wang B; Yung AC; Wang Y; Kozlowski P; van Breemen C; Schrader JW
• Regulatory domain phosphorylation to distinguish the mechanistic basis underlying acute CFTR modulators.
  Am J Physiol Lung Cell Mol Physiol Volume: 301 Page(s): L587 - L597
  10/01/2011 Authors: Pyle LC; Ehrhardt A; Mitchell LH; Fan L; Ren A; Naren AP; Li Y; Clancy JP; Bolger GB; Sorscher EJ
• A BIOCHEMICAL ASSAY FOR DISCOVERY OF GATING MODULATORS BASED ON INTRAMOLECULAR INTERACTIONS BETWEEN NUCLEOTIDE BINDING DOMAIN 1 AND THE FIRST CYTOPLASMIC LOOP OF CFTR
  PEDIATRIC PULMONOLOGY Page(s): 236 - 236
  01/01/2010 Authors: Chung W; Ehrhardt A; Pyle LC; Wang W; Bear CE; Lukacs G; Kirk KL; Sorscher EJ
• Mechanisms underlying potentiator activation of CFTR
  PEDIATRIC PULMONOLOGY Page(s): 305 - 305
  01/01/2007 Authors: Pyle LC; Ehrhardt A; Wang W; Varga K; Nowatarski KJ; Rowe SM; Sorscher EJ
• Distinct mechanisms determine the patterns of differential activation of H-Ras, N-Ras, K-Ras 4B, and M-Ras by receptors for growth factors or antigen.
  Mol Cell Biol Volume: 24 Page(s): 6311 - 6323
  07/01/2004 Authors: Ehrhardt A; David MD; Ehrhardt GRA; Schrader JW
• The hotspots of integration targeted by the site-specific integrase PhiC31 may be cell line dependent
  Volume: 9 Page(s): S307 - S307
  05/01/2004 Authors: Ehrhardt A; Engler JA; Calos MP; Kay MA
• The inhibitory potential of Fc receptor homolog 4 on memory B cells.
  Proc Natl Acad Sci U S A Volume: 100 Page(s): 13489 - 13494
  11/11/2003 Authors: Ehrhardt GRA; Davis RS; Hsu JT; Leu C-M; Ehrhardt A; Cooper MD
• Ras and relatives--job sharing and networking keep an old family together.
  Exp Hematol Volume: 30 Page(s): 1089 - 1106
  10/01/2002 Authors: Ehrhardt A; Ehrhardt GRA; Guo X; Schrader JW