Doctoral Student
Fan Fan is focusing his interests in digital pathology, machine learning, deep-learning, glomerular disease, and biostatistics on several projects.
In 2022, Fan joined the Center for Computational Imaging and Personalized Diagnostics (CCIPD) at Case Western Reserve University as a research assistant. His research interests encompass tools development for batch-effects mitigation and virtual staining, deep learning applications in digital pathology, and biomarker exploration to enhance the prognostication and prediction of kidney diseases. He played a lead role in developing CohortFinder, an open-source tool that mitigates batch effects and enhances the performance of machine learning models in both radiology and digital pathology domains. See arXiv preprint arXiv:2307.08673, 2023. As a member of the Madabhushi Lab, Fan continues working on development of open-source tools to improve machine learning model robustness for medical imaging data.
Over the last 2 years, Fan also has focused on applying image analysis to kidney diseases, leveraging the infrastructure of large consortia such as Cure Glomerulonephropathy (CureGN), the Nephrotic Syndrome Study Network (NEPTUNE), and the Kidney Precision Medicine Project (KPMP). Fan has devised a range of algorithms, utilizing both image processing and deep learning approaches, to segment various kidney structures, such as tubular epithelium, tubular lumen, and tubular basement membrane, from which interpretable hand-crafted features were extracted. His research involves investigating the correlation between these hand-crafted features and clinical outcomes. Through his exploration, he demonstrates that these features play a crucial role in significantly enhancing the accuracy of disease outcome predictions. His work in this area showcases a nuanced understanding of biomarker identification and its potential impact on predicting outcomes related to kidney disease.
Fan is a PhD student and graduate research assistant in the Biomedical Engineering Program at Georgia Tech and Emory University. Fan completed his undergraduate degree in mechanical engineering at Shanghai University and earned his masters degree in electrical engineering from Case Western Reserve University.