Publications

• The Cardioprotective Role of Neutrophil-Specific STING in Myocardial Ischemia/Reperfusion Injury.
  
  09/11/2024 Authors: Brockman ML; Scruggs TA; Wang L; Kabboul G; Calvert JW; Levit RD
• VEGF-delivering PEG hydrogels promote vascularization in the porcine subcutaneous space.
  J Biomed Mater Res A Volume: 112 Page(s): 866 - 880
  06/01/2024 Authors: Quizon MJ; Deppen JN; Barber GF; Kalelkar PP; Coronel MM; Levit RD; Garcia AJ
• Alginate-Encapsulated Mesenchymal Stromal Cells Improve Hind Limb Ischemia in a Translational Swine Model.
  J Am Heart Assoc Volume: 13 Page(s): e029880
  05/07/2024 Authors: Deppen JN; Ginn SC; Tang EO; Wang L; Brockman ML; Levit RD
• Epicardial Hydrogel for Cardiac Gene Delivery
  Volume: 32 Page(s): 312 - 313
  04/22/2024 Authors: Kabboul G; DaMotta L; Doering CB; Garcia AJ; Levit RD
• Placental Lymphatics In Pregnancy And Preeclampsia
  Volume: 133
  08/04/2023 Authors: Niclou B; Ginn S; Wang L; Joseph G; Levit RD
• Targeting Neutrophil Sting And Type I Interferon Activation In Myocardial Ischemia-Reperfusion Injury
  Volume: 133
  08/04/2023 Authors: Brockman ML; Wang L; Calvert JW; Levit RD
• Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.
  Sci Immunol Volume: 8 Page(s): eadg0033
  07/28/2023 Authors: Viox EG; Hoang TN; Upadhyay AA; Nchioua R; Hirschenberger M; Strongin Z; Tharp GK; Pino M; Nguyen K; Harper JL
• Epicardial Hydrogel Delivery of Adeno-Associated Virus to Treat Heart Disease
  Volume: 31 Page(s): 277 - 278
  05/01/2023 Authors: Kabboul G; Caplin JD; Doering CB; Garcia AJ; Levit RD
• TREM2+ and interstitial-like macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques.
  Nat Commun Volume: 14 Page(s): 1914
  04/06/2023 Authors: Upadhyay AA; Viox EG; Hoang TN; Boddapati AK; Pino M; Lee MY-H; Corry J; Strongin Z; Cowan DA; Beagle EN
• Hydrogel delivery of purinergic enzymes improves cardiac ischemia/reperfusion injury.
  J Mol Cell Cardiol Volume: 176 Page(s): 98 - 109
  03/01/2023 Authors: Sayegh MN; Cooney KA; Han WM; Cicka M; Strobel F; Wang L; Garca AJ; Levit RD
• Chronic rheumatologic disorders and cardiovascular disease risk in women.
  Am Heart J Plus Volume: 27 Page(s): 100267
  03/01/2023 Authors: Mehta PK; Levit RD; Wood MJ; Aggarwal N; O'Donoghue ML; Lim SS; Lindley K; Gaignard S; Quesada O; Vatsa N
• Ischemia and no obstructive coronary arteries (INOCA): A narrative review.
  Atherosclerosis Volume: 363 Page(s): 8 - 21
  12/01/2022 Authors: Mehta PK; Huang J; Levit RD; Malas W; Waheed N; Bairey Merz CN
• Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.
  bioRxiv
  10/24/2022 Authors: Hoang TN; Viox EG; Upadhyay AA; Strongin Z; Tharp GK; Pino M; Nchioua R; Hirschenberger M; Gagne M; Nguyen K
• The Role Of Neutrophils In Initiating Type I Interferon Response In Myocardial Ischemia/reperfusion
  Volume: 131
  08/05/2022 Authors: Brockman ML; Wang L; Calvert JW; Levit RD
• The Impact Of Lymphatic Vasculature Post-Cardiac Transplantation On Allograft Function, Fibrotic Remodeling, And Lymphatic Drainage
  Volume: 131
  08/05/2022 Authors: Ginn SC; Levit RD
• Sodium alginate microencapsulation of human mesenchymal stromal cells modulates paracrine signaling response and enhances efficacy for treatment of established osteoarthritis.
  Acta Biomater Volume: 141 Page(s): 315 - 332
  03/15/2022 Authors: McKinney JM; Pucha KA; Doan TN; Wang L; Weinstock LD; Tignor BT; Fowle KL; Levit RD; Wood LB; Willett NJ
• NOT YOUR TYPICAL OBSTRUCTIVE CARDIOMYOPATHY
  Volume: 79 Page(s): 2642 - 2642
  03/08/2022 Authors: Huang J; Brown M; Williams BR; Levit R
• NEUTROPHILS AND NETOSIS IN WOMEN WITH CORONARY MICROVASCULAR DYSFUNCTION: A HYPOTHESIS GENERATING STUDY
  Volume: 79 Page(s): 992 - 992
  03/08/2022 Authors: Levit R; Wang L; Gaignard S; Sayegh M; Vatsa N; Rashid FA; McDowell A; Mehta PK
• COVID HEARTBREAK
  Volume: 79 Page(s): 2345 - 2345
  03/08/2022 Authors: Anees M; Brown MT; Levit R
• AN ENIGMATIC DIAGNOSIS: PROSTHETIC VALVE ENDOCARDITIS AFTER TRANSCATHETER AORTIC VALVE REPLACEMENT
  Volume: 79 Page(s): 1262 - 1262
  03/08/2022 Authors: Davis J; Staloch D; Levit R
• A Swine Hind Limb Ischemia Model Useful for Testing Peripheral Artery Disease Therapeutics.
  J Cardiovasc Transl Res Volume: 14 Page(s): 1186 - 1197
  12/01/2021 Authors: Deppen JN; Ginn SC; Kim NH; Wang L; Voll RJ; Liang SH; Goodman MM; Oshinski JN; Levit RD
• A Swine Hind Limb Ischemia Model Useful for Testing Peripheral Artery Disease Therapeutics
  Journal of Cardiovascular Translational Research Volume: 14 Page(s): 1186 - 1197
  12/01/2021 Authors: Deppen JN; Ginn SC; Kim NH; Wang L; Voll RJ; Liang SH; Goodman MM; Oshinski JN; Levit RD
• TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques.
  bioRxiv
  10/05/2021 Authors: Upadhyay AA; Hoang TN; Pino M; Boddapati AK; Viox EG; Lee MYH; Corry J; Strongin Z; Cowan DA; Beagle EN
• Regeneration of infarcted mouse hearts by cardiovascular tissue formed via the direct reprogramming of mouse fibroblasts.
  Nat Biomed Eng Volume: 5 Page(s): 880 - 896
  08/01/2021 Authors: Cho J; Kim S; Lee H; Rah W; Cho HC; Kim NK; Bae S; Shin DH; Lee MG; Park I-H
• A Hydrogel Strategy to Augment Tissue Adenosine to Improve Hindlimb Perfusion.
  Arterioscler Thromb Vasc Biol Volume: 41 Page(s): e314 - e324
  06/01/2021 Authors: Sayegh MN; Cooney KA; Han WM; Wang L; Strobel F; Hansen LM; Garca AJ; Levit RD
• Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
  Cell Volume: 184 Page(s): 460 - 475.e21
  01/21/2021 Authors: Hoang TN; Pino M; Boddapati AK; Viox EG; Starke CE; Upadhyay AA; Gumber S; Nekorchuk M; Busman-Sahay K; Strongin Z
• Systemic Inflammation in Acute SARS-CoV-2 Infection May Lead to Elevated Cardiac Cytokines and Adverse Remodeling
  Volume: 127 Page(s): E273 - E273
  12/04/2020 Authors: Sayegh M; Cooney KA; Wang L; Hoang T; Viox E; Pino M; Schneider F; Geller R; Paiardini M; Levit R
• Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
  bioRxiv
  09/16/2020 Authors: Hoang TN; Pino M; Boddapati AK; Viox EG; Starke CE; Upadhyay AA; Gumber S; Busman-Sahay K; Strongin Z; Harper JL
• The Role of Impaired Lymphatic Drainage in Cardiac Transplantation
  Volume: 127
  07/31/2020 Authors: Ginn SC; Wang L; Levit RD
• Creation of a Swine Limb Ischemia Model for Quantifying Therapeutic Efficacy in Peripheral Artery Disease
  Volume: 40
  05/01/2020 Authors: Deppen JN; Ginn SC; Kim NH; Wang L; Levit R
• Investigating and Inhibiting Neutrophil Extracellular Trap Formation in the Heart
  Volume: 125
  08/02/2019 Authors: Sayegh MN; Wang L; Shin EY; Han WM; Brown ME; Davis ME; Garcia AJ; Levit RD
• Adenosine from a biologic source regulates neutrophil extracellular traps (NETs).
  J Leukoc Biol Volume: 105 Page(s): 1225 - 1234
  06/01/2019 Authors: Xu K; Cooney KA; Shin EY; Wang L; Deppen JN; Ginn SC; Levit RD
• Quantitative Characterization of a Porcine Peripheral Artery Disease Model to Test an Encapsulated Mesenchymal Stromal Cell Therapy
  Volume: 39
  05/01/2019 Authors: Deppen JN; Ginn SC; Wang L; Goodman MM; Voll RJ; Levit RD
• Therapeutic efficacy of intra-articular delivery of encapsulated human mesenchymal stem cells on early stage osteoarthritis.
  Eur Cell Mater Volume: 37 Page(s): 42 - 59
  01/29/2019 Authors: McKinney JM; Doan TN; Wang L; Deppen J; Reece DS; Pucha KA; Ginn S; Levit RD; Willett NJ
• Minimally Invasive Delivery of Hydrogel-Encapsulated Amiodarone to the Epicardium Reduces Atrial Fibrillation.
  Circ Arrhythm Electrophysiol Volume: 11 Page(s): e006408
  05/01/2018 Authors: Garcia JR; Campbell PF; Kumar G; Langberg JJ; Cesar L; Deppen JN; Shin EY; Bhatia NK; Wang L; Xu K
• Neutrophils Aged Under Oxidative Stress Impede Vascular Repair
  Volume: 38
  05/01/2018 Authors: Okwan-Duodu D; Liu W; Xu K; Shin E; Quintana RA; Joseph G; Hansen L; Sellak H; Levit R; Archer D
• Engineering Vessels as Good as New?
  JACC: Basic to Translational Science Volume: 3 Page(s): 119 - 121
  02/01/2018 Authors: D.Levit R
• Adenosine Production by Biomaterial-Supported Mesenchymal Stromal Cells Reduces the Innate Inflammatory Response in Myocardial Ischemia/Reperfusion Injury.
  J Am Heart Assoc Volume: 7
  01/13/2018 Authors: Shin EY; Wang L; Zemskova M; Deppen J; Xu K; Strobel F; Garca AJ; Tirouvanziam R; Levit RD
• CD73-Mediated Adenosine Production by Mesenchymal Stromal Cells Reduces the Innate Inflammatory Response Following Myocardial Ischemia/Reperfusion Injury
  Volume: 136
  11/14/2017 Authors: Shin EY; Wang L; Zemskova M; Deppen J; Xu K; Garcia AJ; Dahlman J; Tirouvanziam R; Levit RD
• A Minimally Invasive, Translational Method to Deliver Hydrogels to the Heart Throughthe Pericardial Space.
  JACC Basic Transl Sci Volume: 2 Page(s): 601 - 609
  10/01/2017 Authors: Garcia JR; Campbell PF; Kumar G; Langberg JJ; Cesar L; Wang L; Garca AJ; Levit RD
• "Frontiers in Fontan failure: A summary of conference proceedings".
  Congenit Heart Dis Volume: 12 Page(s): 6 - 16
  01/01/2017 Authors: Hebson C; Book W; Elder RW; Ford R; Jokhadar M; Kanter K; Kogon B; Kovacs AH; Levit RD; Lloyd M
• Cardiovascular Regeneration: Biology and Therapy.
  Stem Cells Int Volume: 2017 Page(s): 4163694
  01/01/2017 Authors: Park C; Ban K; Levit RD; Liang W; Park H-J; Wagner MB
• Pericarditis Associated With Acute Zika Virus Infection in a Returning Traveler.
  Open Forum Infect Dis Volume: 4 Page(s): ofx103
  01/01/2017 Authors: Waggoner JJ; Rouphael N; Xu Y; Natrajan M; Lai L; Patel SM; Levit RD; Edupuganti S; Mulligan MJ
• Minimally Invasive Delivery of a Sustained Release Amiodorane Hydrogel to the Epicardium for Refractory Atrial Fibrillation
  Volume: 134
  11/11/2016 Authors: Levit RD; Campbell PF; Garcia J; Langberg JJ; Kumar G; Shin E; Wang L; Marina Z; Garcia AJ
• Mesenchymal Stem Cells Require CD73 Activity to Reduce Leukocyte Associated Inflammation Following Myocardial Ischemia-Reperfusion Injury
  Volume: 134
  11/11/2016 Authors: Shin E; Wang L; Garcia A; Tirouvanziam R; Levit R
• Nature and Nurture: It Matters for Stem Cells, Too.
  JACC Basic Transl Sci Volume: 1 Page(s): 373 - 375
  08/01/2016 Authors: Levit RD
• Alginate microencapsulation of human mesenchymal stem cells as a strategy to enhance paracrine-mediated vascular recovery after hindlimb ischaemia.
  J Tissue Eng Regen Med Volume: 10 Page(s): 222 - 232
  03/01/2016 Authors: Landzuri N; Levit RD; Joseph G; Ortega-Legaspi JM; Flores CA; Weiss D; Sambanis A; Weber CJ; Safley SA; Taylor WR
• Pheochromocytoma Masquerading as "Diabetic Ketoacidosis".
  J Investig Med High Impact Case Rep Volume: 4 Page(s): 2324709616646128
  01/01/2016 Authors: Hedley JS; Law S; Phookan S; Lee MN-F; Ioachimescu A; Levit RD
• An unusual cause of a non-ST segment elevation myocardial infarction: answer.
  Heart Volume: 100 Page(s): 1652
  10/01/2014 Authors: Levit RD; Polomsky M; Vega JD; Martin DR; Kumar G
• An unusual cause of a non-ST segment elevation myocardial infarction: answer
  Heart (British Cardiac Society) Volume: 100 Page(s): 1652
  10/01/2014 Authors: Levit RD; Polomsky M; Vega JD; Martin DR; Kumar G
• Cellular encapsulation enhances cardiac repair.
  J Am Heart Assoc Volume: 2 Page(s): e000367
  10/10/2013 Authors: Levit RD; Landzuri N; Phelps EA; Brown ME; Garca AJ; Davis ME; Joseph G; Long R; Safley SA; Suever JD
• Cellular Encapsulation of Mesenchymal Stem Cells Enhances Cardiac Repair in a Rat Model of Myocardial Infarction
  CIRCULATION Volume: 126
  11/20/2012 Authors: Levit RD; Landazuri N; Phelps EA; Brown ME; Garcia A; Davis ME; Joseph G; Long R; Weber CJ; Safley SA
• High Risk, High Stakes: Optimizing Cardiovascular Risk Assessment in Women
  Current Cardiovascular Risk Reports Volume: 6 Page(s): 176 - 184
  04/01/2012 Authors: Levit RD; Wenger NK
• Induced pluripotent stem cells
  Stem Cells and Revascularization Therapies Page(s): 55 - 104
  12/13/2011 Authors: Han JW; Levit RD; Yoon YS
• A clinical commentary on the article "N-acetylglucosamine conjugated to nanoparticles enhances myocyte uptake and improves delivery of a small molecule p38 inhibitor for post-infarct healing" : N-acetylglucosamine conjugated nanoparticles: translational opportunities and barriers.
  J Cardiovasc Transl Res Volume: 4 Page(s): 644 - 645
  10/01/2011 Authors: Levit RD; Taylor WR
• Computational protein design to reengineer stromal cell-derived factor-1 generates an effective and translatable angiogenic polypeptide analog.
  Circulation Volume: 124 Page(s): S18 - S26
  09/13/2011 Authors: Hiesinger W; Perez-Aguilar JM; Atluri P; Marotta NA; Frederick JR; Fitzpatrick JR; McCormick RC; Muenzer JR; Yang EC; Levit RD
• Oxygen-dependent quenching of phosphorescence used to characterize improved myocardial oxygenation resulting from vasculogenic cytokine therapy.
  J Appl Physiol (1985) Volume: 110 Page(s): 1460 - 1465
  05/01/2011 Authors: Hiesinger W; Vinogradov SA; Atluri P; Fitzpatrick JR; Frederick JR; Levit RD; McCormick RC; Muenzer JR; Yang EC; Marotta NA
• Cardiovascular disease in young women: a population at risk.
  Cardiol Rev Volume: 19 Page(s): 60 - 65
  01/01/2011 Authors: Levit RD; Reynolds HR; Hochman JS
• Computational Protein Design to Re-Engineer Stromal Cell-Derived Factor-alpha (SDF) Generates a Supra-Efficient Angiogenic Polypeptide Analog
  CIRCULATION Volume: 122
  11/23/2010 Authors: Hiesinger W; Perez-Aguilar JM; Atluri P; Marotta NA; Frederick JR; Fitzpatrick JR; McCormick RC; Muenzer JR; Levit RD; Yuan L-J
• Acute myocardial rescue with endogenous endothelial progenitor cell therapy.
  Heart Lung Circ Volume: 19 Page(s): 644 - 654
  11/01/2010 Authors: Atluri P; Panlilio CM; Liao GP; Hiesinger W; Harris DA; McCormick RC; Cohen JE; Jin T; Feng W; Levit RD
• Human peripheral blood-derived CD31+ cells have robust angiogenic and vasculogenic properties and are effective for treating ischemic vascular disease.
  J Am Coll Cardiol Volume: 56 Page(s): 593 - 607
  08/10/2010 Authors: Kim S-W; Kim H; Cho H-J; Lee J-U; Levit R; Yoon Y-S
• Asymptomatic central venous stenosis in hemodialysis patients.
  Radiology Volume: 238 Page(s): 1051 - 1056
  03/01/2006 Authors: Levit RD; Cohen RM; Kwak A; Shlansky-Goldberg RD; Clark TWI; Patel AA; Stavropoulos SW; Mondschein JI; Solomon JA; Tuite CM
• Decreased VO2 in response to acute inspired hypoxia and hypercapnic hypoxia in rabbits (O-cuniculus).
  Volume: 16 Page(s): A46 - A46
  03/20/2002 Authors: Zwemer CF; Campbell S; Coleman E; Ellerman J; Levit R; Lucin K; Ritchie C