Michael Davis PhD
- Wallace H. Coulter Department of Biomedical Engineering at Georgia Tech and Emory
Professor
- (404) 727-9858
- medavis@emory.edu
Overview
Research Interests
-Cardiac Regeneration
-Stem cell therapy
Our laboratory focuses on various aspects of cardiac regeneration and preservation using molecular-based and biomaterials-based approaches to restoring function after cardiac injury.
Academic Appointment
- Associate Professor of Medicine, Emory University School of Medicine
- Assistant Professor of Biomedical Engineering, Emory University School of Medicine & Georgia Institute of Technology
Education
Degrees
- PhD from Emory University
- BA from Rutgers College
Research
Focus
- My research focuses on the role of oxidative stress in cardiac dysfunction following myocardial infarction. Research in the laboratory currently focuses on transgenic mouse models, and through collaborations at Georgia Institute of Technology, the delivery of antioxidant proteins and signaling inhibitors for the preservation/restoration of cardiac function following myocardial infarction.
Publications
-
Investigation of a chronic single-stage sheep Fontan model.
JTCVS Open Volume: 21 Page(s): 268 - 278
10/31/2024 Authors: Kelly JM; Hu Z; Takaesu F; Watanabe T; Storrs J; Blais B; Yuhara S; Morrison A; Nelson K; Ulziibayar A -
A Biomimetic Leaflet Scaffold for Aortic Valve Remodeling.
Adv Healthc Mater Volume: 13 Page(s): e2303972
09/01/2024 Authors: De Jesus Morales KJ; Santosa U; Brazhkina O; Rajurkar P; Jo H; Davis ME -
Mitochondrial citrate carrier SLC25A1 is a dosage-dependent regulator of metabolic reprogramming and morphogenesis in the developing heart.
bioRxiv
05/13/2024 Authors: Ohanele C; Peoples JN; Karlstaedt A; Geiger JT; Gayle AD; Ghazal N; Sohani F; Brown ME; Davis ME; Porter GA -
Myocardial Matrix Hydrogels Mitigate Negative Remodeling and Improve Function in Right HeartFailure Model.
JACC Basic Transl Sci Volume: 9 Page(s): 322 - 338
03/01/2024 Authors: Hunter JD; Mesfin JM; Ahmed T; Chen A; Reimold K; Hancko A; Braden RL; Davis ME; Christman KL -
The Effect of Parent Cell Type on Small Extracellular Vesicle-Derived Vehicle Functionality.
Adv Biol (Weinh) Volume: 8 Page(s): e2300462
03/01/2024 Authors: Bheri S; Park H-J; Hoffman JR; Takaesu F; Davis ME -
Circulating T cell specific extracellular vesicle profiles in cardiac allograft acute cellular rejection.
Am J Transplant Volume: 24 Page(s): 419 - 435
03/01/2024 Authors: Korutla L; Hoffman JR; Rostami S; Hu R; Korutla V; Markmann C; Mullan C; Sotolongo A; Habertheuer A; Romano C -
Customized Loading of microRNA-126 to Small Extracellular Vesicle-Derived Vehicles Improves Cardiac Function after Myocardial Infarction.
ACS Nano Volume: 17 Page(s): 19613 - 19624
10/24/2023 Authors: Bheri S; Brown ME; Park H-J; Brazhkina O; Takaesu F; Davis ME -
Statistical modeling of extracellular vesicle cargo to predict clinical trial outcomes for hypoplastic left heart syndrome.
iScience Volume: 26 Page(s): 107980
10/20/2023 Authors: Hoffman JR; Park H-J; Bheri S; Platt MO; Hare JM; Kaushal S; Bettencourt JL; Lai D; Slesnick TC; Mahle WT -
Optomechanically Actuated Hydrogel Platform for Cell Stimulation with Spatial and Temporal Resolution.
ACS Biomater Sci Eng Volume: 9 Page(s): 5361 - 5375
09/11/2023 Authors: Ramey-Ward AN; Dong Y; Yang J; Ogasawara H; Bremer-Sai EC; Brazhkina O; Franck C; Davis M; Salaita K -
Knockdown of deleterious miRNA in progenitor cell-derived small extracellular vesicles enhances tissue repair in myocardial infarction.
Sci Adv Volume: 9 Page(s): eabo4616
03/03/2023 Authors: Park H-J; Hoffman JR; Brown ME; Bheri S; Brazhkina O; Son YH; Davis ME