Publications

• The Design and Immunogenicity of an HIV-1 Clade C Pediatric Envelope Glycoprotein Stabilized by Multiple Platforms.
  Vaccines (Basel) Volume: 13
  01/22/2025 Authors: Kumar S; Moral-Snchez ID; Singh S; Newby ML; Allen JD; Bijl TPL; Vaghani Y; Jing L; Lodha R; Ortlund EA
• Autoantibodies immuno-mechanically modulate platelet contractile force and bleeding risk.
  Nat Commun Volume: 15 Page(s): 10201
  11/25/2024 Authors: Oshinowo O; Copeland R; Patel A; Shaver N; Fay ME; Jeltuhin R; Xiang Y; Caruso C; Otumala AE; Hernandez S
• Design and immunogenicity of an HIV-1 clade C pediatric envelope glycoprotein stabilized by multiple platforms.
  
  09/19/2024 Authors: Kumar S; Del Moral-Snchez I; Singh S; Newby ML; Allen JD; Bijl TPL; Vaghani Y; Jing L; Ortlund EA; Crispin M
• Rapid, high throughput, automated detection of SARS-CoV-2 neutralizing antibodies against Wuhan-WT, delta and omicron BA1, BA2 spike trimers.
  iScience Volume: 26 Page(s): 108256
  11/17/2023 Authors: Cheedarla N; Verkerke HP; Potlapalli S; McLendon KB; Patel A; Frank F; O'Sick WH; Cheedarla S; Baugh TJ; Damhorst GL
• Light chain of a public SARS-CoV-2 class-3 antibody modulates neutralization against Omicron.
  Cell Rep Volume: 42 Page(s): 113150
  09/26/2023 Authors: Patel A; Kumar S; Lai L; Keen M; Valanparambil R; Chakravarthy C; Laughlin Z; Frank F; Cheedarla N; Verkerke HP
• Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
  Structure Volume: 31 Page(s): 801 - 811.e5
  07/06/2023 Authors: Patel A; Kumar S; Lai L; Chakravarthy C; Valanparambil R; Reddy ES; Gottimukkala K; Bajpai P; Raju DR; Edara VV
• Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody.
  Sci Adv Volume: 8 Page(s): eadd2032
  10/07/2022 Authors: Kumar S; Patel A; Lai L; Chakravarthy C; Valanparambil R; Reddy ES; Gottimukkala K; Davis-Gardner ME; Edara VV; Linderman S
• Deep mutational scanning identifies SARS-CoV-2 Nucleocapsid escape mutations of currently available rapid antigen tests.
  Cell Volume: 185 Page(s): 3603 - 3616.e13
  09/15/2022 Authors: Frank F; Keen MM; Rao A; Bassit L; Liu X; Bowers HB; Patel AB; Cato ML; Sullivan JA; Greenleaf M
• A phospholipid mimetic targeting LRH-1 ameliorates colitis.
  Cell Chem Biol Volume: 29 Page(s): 1174 - 1186.e7
  07/21/2022 Authors: Mays SG; D'Agostino EH; Flynn AR; Huang X; Wang G; Liu X; Millings EJ; Okafor CD; Patel A; Cato ML
• Differential Modulation of Nuclear Receptor LRH-1 through Targeting Buried and Surface Regions of the Binding Pocket.
  J Med Chem Volume: 65 Page(s): 6888 - 6902
  05/12/2022 Authors: Cato ML; Cornelison JL; Spurlin RM; Courouble VV; Patel AB; Flynn AR; Johnson AM; Okafor CD; Frank F; D'Agostino EH
• Rapid, high throughput, automated detection of SARS-CoV-2 neutralizing antibodies against native-like vaccine and delta variant spike trimers.
  Res Sq
  02/16/2022 Authors: Cheedarla N; Verkerke HP; Potlapalli S; McLendon KB; Patel A; Frank F; Damhorst GL; Wu H; O'Sick WH; Graciaa D
• Development of a new class of liver receptor homolog-1 (LRH-1) agonists by photoredox conjugate addition.
  Bioorg Med Chem Lett Volume: 30 Page(s): 127293
  08/15/2020 Authors: Cornelison JL; Cato ML; Johnson AM; D'Agostino EH; Melchers D; Patel AB; Mays SG; Houtman R; Ortlund EA; Jui NT
• Characterization of SETD3 methyltransferase-mediated protein methionine methylation.
  J Biol Chem Volume: 295 Page(s): 10901 - 10910
  08/07/2020 Authors: Dai S; Holt MV; Horton JR; Woodcock CB; Patel A; Zhang X; Young NL; Wilkinson AW; Cheng X
• KRAB domain of ZFP568 disrupts TRIM28-mediated abnormal interactions in cancer cells.
  NAR Cancer Volume: 2 Page(s): zcaa007
  06/01/2020 Authors: Kumar J; Kaur G; Ren R; Lu Y; Lin K; Li J; Huang Y; Patel A; Barton MC; Macfarlan T
• Development of a Versatile and Sensitive Direct Ligand Binding Assay for Human NR5A Nuclear Receptors.
  ACS Med Chem Lett Volume: 11 Page(s): 365 - 370
  03/12/2020 Authors: D'Agostino EH; Flynn AR; Cornelison JL; Mays SG; Patel A; Jui NT; Ortlund EA
• DNA Conformation Induces Adaptable Binding by Tandem Zinc Finger Proteins.
  Cell Volume: 173 Page(s): 221 - 233.e12
  03/22/2018 Authors: Patel A; Yang P; Tinkham M; Pradhan M; Sun M-A; Wang Y; Hoang D; Wolf G; Horton JR; Zhang X
• Structural basis of human PR/SET domain 9 (PRDM9) allele C-specific recognition of its cognate DNA sequence.
  J Biol Chem Volume: 292 Page(s): 15994 - 16002
  09/29/2017 Authors: Patel A; Zhang X; Blumenthal RM; Cheng X
• A placental growth factor is silenced in mouse embryos by the zinc finger protein ZFP568.
  Science Volume: 356 Page(s): 757 - 759
  05/19/2017 Authors: Yang P; Wang Y; Hoang D; Tinkham M; Patel A; Sun M-A; Wolf G; Baker M; Chien H-C; Lai K-YN
• Structural basis for human PRDM9 action at recombination hot spots.
  Genes Dev Volume: 30 Page(s): 257 - 265
  02/01/2016 Authors: Patel A; Horton JR; Wilson GG; Zhang X; Cheng X
• Characterization of How DNA Modifications Affect DNA Binding by C2H2 Zinc Finger Proteins.
  Methods Enzymol Volume: 573 Page(s): 387 - 401
  01/01/2016 Authors: Patel A; Hashimoto H; Zhang X; Cheng X
• Automethylation activities within the mixed lineage leukemia-1 (MLL1) core complex reveal evidence supporting a "two-active site" model for multiple histone H3 lysine 4 methylation.
  J Biol Chem Volume: 289 Page(s): 868 - 884
  01/10/2014 Authors: Patel A; Vought VE; Swatkoski S; Viggiano S; Howard B; Dharmarajan V; Monteith KE; Kupakuwana G; Namitz KE; Shinsky SA
• Structural basis for WDR5 interaction (Win) motif recognition in human SET1 family histone methyltransferases.
  J Biol Chem Volume: 287 Page(s): 27275 - 27289
  08/10/2012 Authors: Dharmarajan V; Lee J-H; Patel A; Skalnik DG; Cosgrove MS
• Allosteric activation of the phosphoinositide phosphatase Sac1 by anionic phospholipids.
  Biochemistry Volume: 51 Page(s): 3170 - 3177
  04/17/2012 Authors: Zhong S; Hsu F; Stefan CJ; Wu X; Patel A; Cosgrove MS; Mao Y
• Mgm101 is a Rad52-related protein required for mitochondrial DNA recombination.
  J Biol Chem Volume: 286 Page(s): 42360 - 42370
  12/09/2011 Authors: Mbantenkhu M; Wang X; Nardozzi JD; Wilkens S; Hoffman E; Patel A; Cosgrove MS; Chen XJ
• Myosin5a tail associates directly with Rab3A-containing compartments in neurons.
  J Biol Chem Volume: 286 Page(s): 14352 - 14361
  04/22/2011 Authors: Wllert T; Patel A; Lee Y-L; Provance DW; Vought VE; Cosgrove MS; Mercer JA; Langford GM
• A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complex.
  J Biol Chem Volume: 286 Page(s): 3359 - 3369
  02/04/2011 Authors: Patel A; Vought VE; Dharmarajan V; Cosgrove MS
• Mixed lineage leukemia: a structure-function perspective of the MLL1 protein.
  FEBS J Volume: 277 Page(s): 1832 - 1842
  04/01/2010 Authors: Cosgrove MS; Patel A
• Structural basis for the recognition of Set1 family Win motifs by WDR5
  FASEB JOURNAL Volume: 24
  04/01/2010 Authors: Dharmarajan V; Patel A; Vought VE; Cosgrove MS
• On the mechanism of multiple lysine methylation by the human mixed lineage leukemia protein-1 (MLL1) core complex.
  J Biol Chem Volume: 284 Page(s): 24242 - 24256
  09/04/2009 Authors: Patel A; Dharmarajan V; Vought VE; Cosgrove MS
• Structure of WDR5 bound to mixed lineage leukemia protein-1 peptide.
  J Biol Chem Volume: 283 Page(s): 32158 - 32161
  11/21/2008 Authors: Patel A; Dharmarajan V; Cosgrove MS
• A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex.
  J Biol Chem Volume: 283 Page(s): 32162 - 32175
  11/21/2008 Authors: Patel A; Vought VE; Dharmarajan V; Cosgrove MS
• The MLL SET domain is a histone H3 lysine 4 mono-methyltransferase that interacts with WDR5 in the pre-SET ATA2 domain.
  FASEB JOURNAL Volume: 22
  04/01/2008 Authors: Patel AB; Dharmarajan V; Cosgrove MS
• Structural basis for the photochemistry of alpha-phycoerythrocyanin.
  Biochemistry Volume: 46 Page(s): 416 - 423
  01/16/2007 Authors: Schmidt M; Patel A; Zhao Y; Reuter W
• Photodynamic action of C-phycocyanins obtained from marine and fresh water cyanobacterial cultures: a comparative study using EPR spin trapping technique.
  Free Radic Res Volume: 40 Page(s): 821 - 825
  08/01/2006 Authors: Paul BT; Patel A; Selvam GS; Mishra S; Ghosh PK; Murugesan R
• Antioxidant potential of C-phycocyanin isolated from cyanobacterial species Lyngbya, Phormidium and Spirulina spp.
  Indian J Biochem Biophys Volume: 43 Page(s): 25 - 31
  02/01/2006 Authors: Patel A; Mishra S; Ghosh PK
• X-ray crystallographic studies on C-phycocyanins from cyanobacteria from different habitats: marine and freshwater.
  Acta Crystallogr Sect F Struct Biol Cryst Commun Volume: 61 Page(s): 844 - 847
  09/01/2005 Authors: Satyanarayana L; Suresh CG; Patel A; Mishra S; Ghosh PK
• Purification and characterization of C-Phycocyanin from cyanobacterial species of marine and freshwater habitat.
  Protein Expr Purif Volume: 40 Page(s): 248 - 255
  04/01/2005 Authors: Patel A; Mishra S; Pawar R; Ghosh PK
• Kinetic studies on thermal denaturation of C-phycocyanin.
  Indian J Biochem Biophys Volume: 41 Page(s): 254 - 257
  10/01/2004 Authors: Patel A; Pawar R; Mishra S; Sonawane S; Ghosh PK