Welcome to the Conn Lab
We use modern biochemical and biophysical methods to study the structures, interactions and biological functions of biomedically important RNA and protein molecules. Current topics include mechanisms of bacterial antibiotic resistance that arise through ribosomal RNA modification and drug efflux systems, and RNA-mediated regulation of host cell innate immune responses.
Research Highlights
Congratulations to BCDB graduate student Sam Schwartz who published her latest studies of OAS1 activation by specific RNA sequences and motifs in Nucleic Acids Research. Read more about Sam’s work at NAR.
Now in print in Antimicrobial Agents & Chemotherapy – our study of substrate selection by the efflux system MexXY-OprM by postdoc Debayan Dey and MMG student Logan Kavanaugh. Congrats! Read more at AAC.
