Laura Hansen
Overview
Dr. Hansens lab studies the interactions between satellite cells and the vasculature. Satellite cells are skeletal muscle progenitor cells that are known to play an important role in muscle repair after injury and adaptation to exercise. However, the Hansen lab focuses on a previously underexplored role of satellite cells in vascular growth. They have found that satellite cells, when activated, produced a number of chemoattractant growth factors that drive the migration of vascular smooth muscle and endothelial cells which in an important factor in the growth and development of blood vessels. This area is of particular interest in the context of peripheral artery disease, where patients suffer from ischemic tissue damage but treatment options are still limited. The lab has shown that ischemia stimulates satellite cells and are exploring ways to harness their angiogenic properties in vivo or through therapeutically delivered cells.
Dr. Hansen received her BS in Bioengineering from the University of Pittsburgh in 2007 and PhD in Bioengineering from the Georgia Institute of Technology in 2012. She then completed her post-doctoral fellowship at Emory University in Cardiology. She is currently an Assistant Professor in the Department of Medicine and Division of Cardiology and recently received a Career Development Award from the American Heart Association.
Academic Appointment
- Associate Program Director, Academic Basic Scientist Research Pathway, Emory University
- Program Faculty BioEngineering, Georgia Institute of Technology
- Program Faculty Molecular Systems and Pharmacology Graduate Program, Emory University
- Program Faculty Biomedical Engineering, Emory University/Georgia Institute of Technology
- Assistant Professor of Medicine, Emory University
Education
Degrees
- PhD from Georgia Institute of Technology
- BS from University of Pittsburgh
Research
Publications
-
Is Laser Doppler Perfusion Imaging Trulya "Gold Standard" for Preclinical Peripheral Artery Disease Research?
JACC Basic Transl Sci Volume: 10 Page(s): 104 - 106
01/01/2025 Authors: Oh DG; Hansen L; Taylor WR -
Increasing nitric oxide bioavailability fails to improve collateral vessel formation in humanized sickle cell mice.
Lab Invest Volume: 102 Page(s): 805 - 813
08/01/2022 Authors: Lewis CV; Sellak H; Hansen L; Joseph G; Hurtado J; Archer DR; Jun H-W; Brown LA; Taylor WR -
Satellite Cell Expression of RAGE (Receptor for Advanced Glycation end Products) Is Important for Collateral Vessel Formation.
J Am Heart Assoc Volume: 10 Page(s): e022127
11/02/2021 Authors: Hansen L; Joseph G; Valdivia A; Taylor WR -
Optimization of Oxygen Delivery Within Hydrogels.
J Biomech Eng Volume: 143
10/01/2021 Authors: Mavris SM; Hansen LM -
A Hydrogel Strategy to Augment Tissue Adenosine to Improve Hindlimb Perfusion.
Arterioscler Thromb Vasc Biol Volume: 41 Page(s): e314 - e324
06/01/2021 Authors: Sayegh MN; Cooney KA; Han WM; Wang L; Strobel F; Hansen LM; Garca AJ; Levit RD -
Critical Limb Ischemia Induces Remodeling of Skeletal Muscle Motor Unit, Myonuclear-, and Mitochondrial-Domains.
Sci Rep Volume: 9 Page(s): 9551
07/02/2019 Authors: Mohiuddin M; Lee NH; Moon JY; Han WM; Anderson SE; Choi JJ; Shin E; Nakhai SA; Tran T; Aliya B -
Ischemia-reperfusion Injury Remodels Skeletal Muscle Motor Unit, Myonuclear-, And Mitochondrial-domains
Volume: 51 Page(s): 497 - 498
06/01/2019 Authors: Lee NH; Mohiuddin M; Moon A; Han W; Anderson S; Choi J; Shin E; Nakhai S; Thu T; Aliya B -
Stressed Neutrophils Impede Vascular Repair
Volume: 138
11/06/2018 Authors: Okwan-Duodu D; Liu W; Xu K; Quintana R; Hansen L; Sellak H; Joseph G; Levit R; Archer D; Taylor WR -
The small heat shock protein HSPB1 protects mice from sepsis.
Sci Rep Volume: 8 Page(s): 12493
08/21/2018 Authors: Breed ER; Hilliard CA; Yoseph B; Mittal R; Liang Z; Chen C-W; Burd EM; Brewster LP; Hansen LM; Gleason RL -
Impaired Collateral Vessel Formation in Sickle Cell Disease.
Arterioscler Thromb Vasc Biol Volume: 38 Page(s): 1125 - 1133
05/01/2018 Authors: Okwan-Duodu D; Hansen L; Joseph G; Lyle AN; Weiss D; Archer DR; Taylor WR