David Rye PhD/MD
Academic Appointment
- Professor (tenure), Neurology, Emory University
Education
Degrees
- MD from University of Chicago
- PhD from University of Chicago
- BS from Wayne State University
Research
Focus
- The focus of the basic and clinical laboratories is upon the neural substrates and genes that modulate normal and pathologic sleep/wake states. The present emphasis is upon substrates that directly or indirectly modulate dopamines influences upon sleep/wake state, Restless Legs Syndrome, and the so-called primary hypersomnias. Experimental investigations include anatomical-physiological investigations of transgenic mice, rat, and non-human primate models of disease, and human disease.
Publications
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Modafinil Versus Amphetamine-Dextroamphetamine For Idiopathic Hypersomnia and Narcolepsy Type 2: A Randomized, Blinded, Non-inferiority Trial.
CNS Drugs Volume: 38 Page(s): 909 - 920
11/01/2024 Authors: Trotti LM; Blake T; Hoque R; Rye DB; Sharma S; Bliwise DL -
Validation and performance of the sleep inertia questionnaire in central disorders of hypersomnolence.
Sleep Med Volume: 121 Page(s): 352 - 358
09/01/2024 Authors: Sung E-R; Maness CB; Cook JD; Vascan AM; Moron D; Saini P; Rye DB; Plante DT; Trotti LM -
Genome-wide meta-analyses of restless legs syndrome yield insights into genetic architecture, disease biology and risk prediction.
Nat Genet Volume: 56 Page(s): 1090 - 1099
06/01/2024 Authors: Schormair B; Zhao C; Bell S; Didriksen M; Nawaz MS; Schandra N; Stefani A; Hgl B; Dauvilliers Y; Bachmann CG -
GWAS meta-analysis reveals key risk loci in essential tremor pathogenesis.
Commun Biol Volume: 7 Page(s): 504
04/26/2024 Authors: Skuladottir AT; Stefansdottir L; Halldorsson GH; Stefansson OA; Bjornsdottir A; Jonsson P; Palmadottir V; Thorgeirsson TE; Walters GB; Gisladottir RS -
Restless legs syndrome, periodic limb movements of sleep, and subclinical cardiovascular disease.
Sleep Biol Rhythms Volume: 22 Page(s): 259 - 267
04/01/2024 Authors: Hochstrasser KJ; Rogers SC; Quyyumi A; Johnson D; Pak V; Shah AJ; Rye DB; Trotti LM -
Feigning daytime sleepiness: potential effects on the psychomotor vigilance test.
Sleep Volume: 46
10/11/2023 Authors: Mariano C; Moron D; Maness C; Olvera V; Saini P; Rye DB; Bliwise DL; Trotti LM -
Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsy.
Nat Commun Volume: 14 Page(s): 2709
05/15/2023 Authors: Ollila HM; Sharon E; Lin L; Sinnott-Armstrong N; Ambati A; Yogeshwar SM; Hillary RP; Jolanki O; Faraco J; Einen M -
Commonly Used Therapeutics Associated with Changes in Arousal Inhibit GABAAR Activation.
Biomolecules Volume: 13
02/15/2023 Authors: Kaplan A; Nash AI; Freeman AAH; Lewicki LG; Rye DB; Trotti LM; Brandt AL; Jenkins A -
Consensus guidelines on the construct validity of rodent models of restless legs syndrome.
Dis Model Mech Volume: 15
08/01/2022 Authors: Salminen AV; Clemens S; Garca-Borreguero D; Ghorayeb I; Li Y; Manconi M; Ondo W; Rye D; Siegel JM; Silvani A -
The Psychomotor Vigilance Test as a measure of alertness and sleep inertia in people with central disorders of hypersomnolence.
J Clin Sleep Med Volume: 18 Page(s): 1395 - 1403
05/01/2022 Authors: Trotti LM; Saini P; Bremer E; Mariano C; Moron D; Rye DB; Bliwise DL -
Usefulness of Restless Legs Symptoms to Predict Adverse Cardiovascular Outcomes in Men With Coronary Artery Disease.
Am J Cardiol Volume: 162 Page(s): 41 - 48
01/01/2022 Authors: Almuwaqqat Z; Kim JH; Islam SJ; Mehta A; Ahmad S; Wehbe M; Hazim K; Dhindsa D; Beydoun N; Lemma M -
Regional brain metabolism differs between narcolepsy type 1 and idiopathic hypersomnia.
Sleep Volume: 44
08/13/2021 Authors: Trotti LM; Saini P; Crosson B; Meltzer CC; Rye DB; Nye JA -
Kleine-Levin syndrome is associated with birth difficulties and genetic variants in the TRANK1 gene loci.
Proc Natl Acad Sci U S A Volume: 118
03/23/2021 Authors: Ambati A; Hillary R; Leu-Semenescu S; Ollila HM; Lin L; During EH; Farber N; Rico TJ; Faraco J; Leary E -
Consensus Guidelines on Rodent Models of Restless Legs Syndrome.
Mov Disord Volume: 36 Page(s): 558 - 569
03/01/2021 Authors: Salminen AV; Silvani A; Allen RP; Clemens S; Garcia-Borreguero D; Ghorayeb I; Ferr S; Li Y; Ondo W; Picchietti DL -
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis.
Commun Biol Volume: 4 Page(s): 156
02/03/2021 Authors: Bell S; Rigas AS; Magnusson MK; Ferkingstad E; Allara E; Bjornsdottir G; Ramond A; Srensen E; Halldorsson GH; Paul DS -
Cerebrospinal Fluid Hypocretin and Nightmares in Dementia Syndromes.
Dement Geriatr Cogn Dis Extra Volume: 11 Page(s): 19 - 25
01/01/2021 Authors: Trotti LM; Bliwise DL; Keating GL; Rye DB; Hu WT -
Sleep/Wake Behavior and EEG Signatures of the TgF344-AD Rat Model at the Prodromal Stage.
Int J Mol Sci Volume: 21
12/05/2020 Authors: Kreuzer M; Keating GL; Fenzl T; Hrtner L; Sinon CG; Hajjar I; Ciavatta V; Rye DB; Garca PS -
A genome-wide meta-analysis yields 46 new loci associating with biomarkers of iron homeostasis
Volume: 28 Page(s): 107 - 108
12/01/2020 Authors: Ferkingstad E; Magnusson MK; Bell S; Rigas AS; Allara E; Bjornsdottir G; Ramond A; Sorensen E; Halldorsson GH; Paul DS -
Large genome-wide association study identifies three novel risk variants for restless legs syndrome.
Commun Biol Volume: 3 Page(s): 703
11/25/2020 Authors: Didriksen M; Nawaz MS; Dowsett J; Bell S; Erikstrup C; Pedersen OB; Srensen E; Jennum PJ; Burgdorf KS; Burchell B -
Myotonic Dystrophy Phenocopies Sleep Features of Idiopathic Hypersomnia
Volume: 88 Page(s): S229 - S230
10/01/2020 Authors: Chen ZY; Trotti LM; Rye DB -
Evidence for communication of peripheral iron status to cerebrospinal fluid: clinical implications for therapeutic strategy.
Fluids Barriers CNS Volume: 17 Page(s): 28
04/16/2020 Authors: Connor JR; Duck K; Patton S; Simpson IA; Trotti LM; Allen R; Earley CJ; Rye D -
FDG-PET IMAGING IN NARCOLEPSY TYPE 1, IDIOPATHIC HYPERSOMNIA, AND NON-SLEEPY CONTROLS
Volume: 43 Page(s): A292 - A292
04/01/2020 Authors: Trotti L; Meltzer C; Rye D; Nye J -
TOX3 gene variant could be associated with painful restless legs.
Sleep Med Volume: 65 Page(s): 4 - 7
01/01/2020 Authors: Karroum EG; Saini PS; Trotti LM; Rye DB -
A Sleepy Patient With Frequent Falls.
J Clin Sleep Med Volume: 15 Page(s): 1691 - 1693
11/15/2019 Authors: Chada A; Dholakia S; Rye D -
A Sleepy Patient With Frequent Falls.
J Clin Sleep Med
10/04/2019 Authors: Chada A; Dholakia S; Rye D -
Focus on the pedunculopontine nucleus. Consensus review from the May 2018 brainstem society meeting in Washington, DC, USA.
Clin Neurophysiol Volume: 130 Page(s): 925 - 940
06/01/2019 Authors: Garcia-Rill E; Saper CB; Rye DB; Kofler M; Nonnekes J; Lozano A; Valls-Sol J; Hallett M -
Systemic exertion intolerance disease/chronic fatigue syndrome is common in sleep centre patients with hypersomnolence: A retrospective pilot study.
J Sleep Res Volume: 28 Page(s): e12689
06/01/2019 Authors: Maness C; Saini P; Bliwise DL; Olvera V; Rye DB; Trotti LM -
PHENOTYPIC CHARACTERIZATION OF RLS IN AFRICAN-AMERICANS
Volume: 42
04/01/2019 Authors: Saini P; Forbes A; Rye DB -
THE PSYCHOMOTOR VIGILANCE TASK AS A DIAGNOSTIC TOOL FOR HYPERSOMNOLENCE
Volume: 42
04/01/2019 Authors: Moron D; Mariano C; Bliwise DL; Maness C; Olvera V; Saini P; Rye D; Trotti LM -
INITIAL USE OF THE SLEEP INERTIA QUESTIONNAIRE IN HYPERSOMNOLENCE DISORDERS
Volume: 42
04/01/2019 Authors: Maness CB; Moron D; Bliwise D; Saini P; Rye D; Trotti LM -
VISUAL PROCESSING SPEED AFTER BRIEF NAPS IN HYPERSOMNOLENT PATIENTS: MSLT AND PVT CORRELATES
Volume: 42
04/01/2019 Authors: Saini P; Trotti LM; Rye DB -
BUPRENORPHINE/NALOXONE TREATMENT OF REFRACTORY RLS
Volume: 42
04/01/2019 Authors: Forbes A; Saini P; Rye DB -
Inter-rater agreement for visual discrimination of phasic and tonic electromyographic activity in sleep.
Sleep Volume: 41
07/01/2018 Authors: Bliwise DL; Fairley J; Hoff S; Rosenberg RS; Rye DB; Schulman DA; Trotti LM -
Postnatal hypoxia evokes persistent changes within the male rat's dopaminergic system.
Sleep Breath Volume: 22 Page(s): 547 - 554
05/01/2018 Authors: Decker MJ; Jones KA; Keating GL; Rye DB -
WORKING MEMORY AND PSYCHOMOTOR VIGILANCE PERFORMANCE AFTER BRIEF NAPS IN HYPERSOMNOLENT PATIENTS: MSLT CORRELATES
Volume: 41 Page(s): A229 - A229
04/01/2018 Authors: Saini P; Bremer E; Broyles S; Rye D; Trotti L -
Frequency of and Factors Associated With Obstructive Sleep Apnea and Periodic Limb Movements in Stroke and TIA Patients.
Neurologist Volume: 23 Page(s): 67 - 70
03/01/2018 Authors: Gadodia G; Rangaraju S; Raza SA; Razzak A; Marmarchi L; Davis B; Henriquez L; Trotti LM; Rye D; Nahab F -
The MSLT is Repeatable in Narcolepsy Type 1 But Not Narcolepsy Type 2: A Retrospective Patient Study.
J Clin Sleep Med Volume: 14 Page(s): 65 - 74
01/15/2018 Authors: Ruoff C; Pizza F; Trotti LM; Sonka K; Vandi S; Cheung J; Pinto S; Einen M; Simakajornboon N; Han F -
IMPAIRED CONSCIOUSNESS STATES IN MYOTONIC DYSTROPHY-TYPE 1 MEDIATION BY gamma-AMINO BUTYRIC ACID (GABA)
Volume: 40 Page(s): E285 - E285
12/01/2017 Authors: McConnell O; Wang E; Bassell G; Moody O; Jenkins A; Freeman A; Trotti LM; Saini P; Rye D -
Hypocretin measurement: shelf age of radioimmunoassay kit, but not freezer time, influences assay variability.
Scand J Clin Lab Invest Volume: 77 Page(s): 390 - 393
09/01/2017 Authors: Keating G; Bliwise DL; Saini P; Rye DB; Trotti LM -
Restless legs syndrome with augmentation successfully treated with IV iron.
Neurol Clin Pract Volume: 7 Page(s): e26 - e28
06/01/2017 Authors: LaBarbera V; Trotti LM; Rye D -
Rigor, reproducibility, and in vitro cerebrospinal fluid assays: The devil in the details.
Ann Neurol Volume: 81 Page(s): 904 - 907
06/01/2017 Authors: Moody OA; Talwar S; Jenkins MA; Freeman AA; Trotti LM; Garca PS; Bliwise D; Lynch JW; Cherson B; Hernandez EM -
FREQUENCY AND PREDICTORS OF SYSTEMIC EXERTION INTOLERANCE DISEASE/CHRONIC FATIGUE SYNDROME AMONG SLEEP CENTER PATIENTS REFERRED FOR HYPERSOMNOLENCE EVALUATION
Volume: 40 Page(s): A243 - A244
04/01/2017 Authors: Maness CB; Saini P; Bliwise DL; Olvera V; Rye DB; Trotti L -
WORSENING PSYCHOMOTOR VIGILANCE AFTER BRIEF NAPS IN HYPERSOMNOLENT PATIENTS: MSLT NAP CORRELATES
Volume: 40 Page(s): A242 - A242
04/01/2017 Authors: Saini P; Bremer EM; Broyles SS; Rye DB; Trotti L -
Hypersomnia: Evaluation, Treatment, and Social and Economic Aspects.
Sleep Med Clin Volume: 12 Page(s): 47 - 60
03/01/2017 Authors: Saini P; Rye DB -
Genetics of restless legs syndrome.
Sleep Med Volume: 31 Page(s): 18 - 22
03/01/2017 Authors: Winkelmann J; Schormair B; Xiong L; Dion PA; Rye DB; Rouleau GA -
Animal models of RLS phenotypes.
Sleep Med Volume: 31 Page(s): 23 - 28
03/01/2017 Authors: Allen RP; Donelson NC; Jones BC; Li Y; Manconi M; Rye DB; Sanyal S; Winkelmann J -
Are Periodic Limb Movements and Obstructive Sleep Apnea Associated with Atrial Fibrillation or Resistant Hypertension in Stroke and TIA Patients?
Volume: 48
02/01/2017 Authors: Raza SA; Rangaraju S; Gadodia G; Marmarchi L; Razzak A; Trotti LM; Rye D; Davis B; Henriquez L; Belagaje S -
In Reply.
Anesthesiology Volume: 126 Page(s): 352 - 353
02/01/2017 Authors: Safavynia SA; Keating G; Speigel I; Fidler JA; Kreuzer M; Rye DB; Jenkins A; Garca PS -
Flumazenil for the Treatment of Refractory Hypersomnolence: Clinical Experience with 153 Patients.
J Clin Sleep Med Volume: 12 Page(s): 1389 - 1394
10/15/2016 Authors: Trotti LM; Saini P; Koola C; LaBarbera V; Bliwise DL; Rye DB -
The ICSD-3 and DSM-5 guidelines for diagnosing narcolepsy: clinical relevance and practicality.
Curr Med Res Opin Volume: 32 Page(s): 1611 - 1622
10/01/2016 Authors: Ruoff C; Rye D -
Effects of -Aminobutyric Acid Type A Receptor Modulation by Flumazenil on Emergence from General Anesthesia.
Anesthesiology Volume: 125 Page(s): 147 - 158
07/01/2016 Authors: Safavynia SA; Keating G; Speigel I; Fidler JA; Kreuzer M; Rye DB; Jenkins A; Garca PS -
Rotigotine's effect on PLM-associated blood pressure elevations in restless legs syndrome: An RCT.
Neurology Volume: 86 Page(s): 1785 - 1793
05/10/2016 Authors: Bauer A; Cassel W; Benes H; Kesper K; Rye D; Sica D; Winkelman JW; Bauer L; Grieger F; Joeres L -
The Molecular Genetics of Restless Legs Syndrome.
Sleep Med Clin Volume: 10 Page(s): 227 - xii
09/01/2015 Authors: Rye DB -
Clarithromycin in -aminobutyric acid-Related hypersomnolence: A randomized, crossover trial.
Ann Neurol Volume: 78 Page(s): 454 - 465
09/01/2015 Authors: Trotti LM; Saini P; Bliwise DL; Freeman AA; Jenkins A; Rye DB -
Inhibition of tumor necrosis factor improves sleep continuity in patients with treatment resistant depression and high inflammation.
Brain Behav Immun Volume: 47 Page(s): 193 - 200
07/01/2015 Authors: Weinberger JF; Raison CL; Rye DB; Montague AR; Woolwine BJ; Felger JC; Haroon E; Miller AH -
Improvement in daytime sleepiness with clarithromycin in patients with GABA-related hypersomnia: Clinical experience.
J Psychopharmacol Volume: 28 Page(s): 697 - 702
07/01/2014 Authors: Trotti LM; Saini P; Freeman AA; Bliwise DL; Garca PS; Jenkins A; Rye DB -
Paralysis lost: a new cause for a common parasomnia?
Lancet Neurol Volume: 13 Page(s): 531 - 532
06/01/2014 Authors: Rye D -
Challenges in diagnosing narcolepsy without cataplexy: a consensus statement.
Sleep Volume: 37 Page(s): 1035 - 1042
06/01/2014 Authors: Baumann CR; Mignot E; Lammers GJ; Overeem S; Arnulf I; Rye D; Dauvilliers Y; Honda M; Owens JA; Plazzi G -
Wavelet analysis for detection of phasic electromyographic activity in sleep: influence of mother wavelet and dimensionality reduction.
Comput Biol Med Volume: 48 Page(s): 77 - 84
05/01/2014 Authors: Fairley JA; Georgoulas G; Smart OL; Dimakopoulos G; Karvelis P; Stylios CD; Rye DB; Bliwise DL -
Further experience using clarithromycin in patients with Kleine-Levin syndrome.
J Clin Sleep Med Volume: 10 Page(s): 457 - 458
04/15/2014 Authors: Trotti LM; Bliwise DL; Rye DB -
Idiopathic recurrent stupor: Munchausen by proxy and medical litigation.
Sleep Volume: 37 Page(s): 211
01/01/2014 Authors: Plazzi G; Rye D; Vignatelli L; Riva R; Lugaresi E -
Chronic interferon- decreases dopamine 2 receptor binding and striatal dopamine release in association with anhedonia-like behavior in nonhuman primates.
Neuropsychopharmacology Volume: 38 Page(s): 2179 - 2187
10/01/2013 Authors: Felger JC; Mun J; Kimmel HL; Nye JA; Drake DF; Hernandez CR; Freeman AA; Rye DB; Goodman MM; Howell LL -
The molecular basis of restless legs syndrome.
Curr Opin Neurobiol Volume: 23 Page(s): 895 - 900
10/01/2013 Authors: Freeman AAH; Rye DB -
A prospective photographic study of the ocular fundus in obstructive sleep apnea.
J Neuroophthalmol Volume: 33 Page(s): 241 - 246
09/01/2013 Authors: Fraser CL; Bliwise DL; Newman NJ; Lamirel C; Collop NA; Rye DB; Trotti LM; Biousse V; Bruce BB -
Test-retest reliability of the multiple sleep latency test in narcolepsy without cataplexy and idiopathic hypersomnia.
J Clin Sleep Med Volume: 9 Page(s): 789 - 795
08/15/2013 Authors: Trotti LM; Staab BA; Rye DB -
Restless legs syndrome, pica, and iron status in blood donors.
Transfusion Volume: 53 Page(s): 1645 - 1652
08/01/2013 Authors: Spencer BR; Kleinman S; Wright DJ; Glynn SA; Rye DB; Kiss JE; Mast AE; Cable RG; REDS-II RISE Analysis Group -
Obstructive sleep apnea in idiopathic intracranial hypertension: comparison with matched population data.
J Neurol Volume: 260 Page(s): 1748 - 1751
07/01/2013 Authors: Thurtell MJ; Trotti LM; Bixler EO; Rye DB; Bliwise DL; Newman NJ; Biousse V; Bruce BB -
Computerized detection of movement artifacts in polysomnogram data
Volume: 260 Page(s): S202 - S202
06/01/2013 Authors: Fairley J; Georgoulas G; Johnson-Long A; Stylios C; Bliwise D; Rye D -
Restless legs syndrome in children with chronic kidney disease.
Pediatr Nephrol Volume: 28 Page(s): 773 - 795
05/01/2013 Authors: Riar SK; Leu RM; Turner-Green TC; Rye DB; Kendrick-Allwood SR; McCracken C; Bliwise DL; Greenbaum LA -
Obituary for Charlotte McCutchen, MD
SLEEP Volume: 36 Page(s): 291 - 291
02/01/2013 Authors: Malow B; Rye D; Mignot E; Sato S -
Daytime REM sleep in Parkinson's disease.
Parkinsonism Relat Disord Volume: 19 Page(s): 101 - 103
01/01/2013 Authors: Bliwise DL; Trotti LM; Juncos JJ; Factor SA; Freeman A; Rye DB -
Modulation of vigilance in the primary hypersomnias by endogenous enhancement of GABAA receptors.
Sci Transl Med Volume: 4 Page(s): 161ra151
11/21/2012 Authors: Rye DB; Bliwise DL; Parker K; Trotti LM; Saini P; Fairley J; Freeman A; Garcia PS; Owens MJ; Ritchie JC -
Restless legs syndrome and periodic leg movements of sleep.
Neurol Clin Volume: 30 Page(s): 1137 - 1166
11/01/2012 Authors: Rye DB; Trotti LM -
Elevated C-reactive protein is associated with severe periodic leg movements of sleep in patients with restless legs syndrome.
Brain Behav Immun Volume: 26 Page(s): 1239 - 1243
11/01/2012 Authors: Trotti LM; Rye DB; De Staercke C; Hooper WC; Quyyumi A; Bliwise DL -
Inability to replicate cerebrospinal fluid histamine deficits in the primary hypersomnias: a back to the drawing board moment.
Sleep Volume: 35 Page(s): 1315 - 1317
10/01/2012 Authors: Rye DB -
Daytime alertness in Parkinson's disease: potentially dose-dependent, divergent effects by drug class.
Mov Disord Volume: 27 Page(s): 1118 - 1124
08/01/2012 Authors: Bliwise DL; Trotti LM; Wilson AG; Greer SA; Wood-Siverio C; Juncos JJ; Factor SA; Freeman A; Rye DB -
Sleep fragmentation and motor restlessness in a Drosophila model of Restless Legs Syndrome.
Curr Biol Volume: 22 Page(s): 1142 - 1148
06/19/2012 Authors: Freeman A; Pranski E; Miller RD; Radmard S; Bernhard D; Jinnah HA; Betarbet R; Rye DB; Sanyal S -
Periodic leg movements in sleep in elderly patients with Parkinsonism and Alzheimer's disease.
Eur J Neurol Volume: 19 Page(s): 918 - 923
06/01/2012 Authors: Bliwise DL; Trotti LM; Yesavage JA; Rye DB -
Respect for muscle.
Sleep Volume: 35 Page(s): 743 - 744
06/01/2012 Authors: Bliwise DL; Rye DB -
Effects of 24-h Transdermal Delivery of Rotigotine on the Core Symptoms and Symptom Impact of Restless Legs Syndrome/Willis-Ekbom Disease: A Post Hoc Analysis of IRLS Single Item Data from a 6-Month Placebo-Controlled European Study
Volume: 78
04/01/2012 Authors: Garcia-Borreguero D; Kohnen R; Rye D; Dohin E; Grieger F; Moran K; Allen R -
Photographic Assessment of Optic Disc and Retinal Vasculature in Obstructive Sleep Apnea (OSA) Patients
Volume: 78
04/01/2012 Authors: Bruce B; Fraser C; Bliwise D; Trotti L-M; Collop N; Rye D; Newman N; Biousse V -
Rotigotine Improves Core Symptoms and Symptom Impact in Patients with Restless Legs Syndrome/Willis-Ekbom Disease: A Post Hoc Analysis of IRLS Single Item Data from a 6-Month Placebo-Controlled US Study
Volume: 78
04/01/2012 Authors: Allen R; Rye D; Dohin E; Grieger F; Moran K; Kohnen R -
Encephalopathy Responsive to Zolpidem.
Volume: 60 Page(s): S76 - S76
04/01/2012 Authors: Howard M; Rye D; Greene J; Levey AI -
FURTHER EVIDENCE OF A NARCOLEPTIC PHENOTYPE IN PARKINSON'S DISEASE (PD)
Volume: 35 Page(s): A280 - A280
01/01/2012 Authors: Bliwise DL; Trotti L; Juncos J; Factor SA; Wilson A; Greer S; Rye DB -
BEDPARTNER REPORTED DREAM ENACTMENT BEHAVIOR MEASURED WITH THE UNIVERSITY OF MICHIGAN RBD QUESTIONNAIRE (UMRBDQ) CORRELATES WITH DAYTIME ALERTNESS INDEPENDENTLY FROM MOTOR DISABILITY IN PARKINSON'S DISEASE (PD)
Volume: 35 Page(s): A438 - A438
01/01/2012 Authors: Bliwise DL; Trotti L; Juncos J; Factor SA; Wilson A; Greer S; Rye DB -
CLARITHROMYCIN REDUCES SLEEPINESS AND IMPROVES VIGILANCE IN PATIENTS WITH CENTRAL NERVOUS SYSTEM HYPERSOMNIAS
Volume: 35 Page(s): A276 - A277
01/01/2012 Authors: Trotti L; Stout AK; Saini P; Freeman A; Jenkins A; Garcia PS; Rye DB -
EFFECTS OF ROTIGOTINE TRANSDERMAL SYSTEM ON SYMPTOM SEVERITY AND SYMPTOM IMPACT IN PATIENTS WITH RESTLESS LEGS SYNDROME
Volume: 35 Page(s): A257 - A258
01/01/2012 Authors: Allen RP; Durmer JS; Garcia-Borreguero D; Rye DB; Dohin E; Grieger F; Moran K; Kohnen R -
The Berlin questionnaire screens for obstructive sleep apnea in idiopathic intracranial hypertension.
J Neuroophthalmol Volume: 31 Page(s): 316 - 319
12/01/2011 Authors: Thurtell MJ; Bruce BB; Rye DB; Newman NJ; Biousse V -
Endogenous GABA(A) Receptor Enhancement Modulates Vigilance in the Primary Hypersomnias
Volume: 70 Page(s): S23 - S23
10/01/2011 Authors: Rye DB; Parker K; Trotti LM; Garcia PS; Ritchie JC; Owens MJ; Morrow L; Bliwise DL; Jenkins A -
Restless abdomen: a phenotypic variant of restless legs syndrome.
Neurology Volume: 77 Page(s): 1283 - 1286
09/27/2011 Authors: Prez-Daz H; Iranzo A; Rye DB; Santamara J -
Heart rate changes accompanying periodic leg movements during sleep in narcoleptic patients.
Sleep Volume: 34 Page(s): 409 - 410
04/01/2011 Authors: Ferri R; Zucconi M; Rye DB -
LEVO-DOPA (L-DOPA) AND DOPAMINE AGONIST (DA)-NAIVE IDIOPATHIC PARKINSON'S DISEASE (PD) PATIENTS DEMONSTRATE MAINTENANCE OF WAKEFULNESS TEST (MWT)-DEFINED ALERTNESS
Volume: 34 Page(s): A220 - A221
01/01/2011 Authors: Bliwise DL; Trotti L; Wilson A; Greer S; Juncos J; Rye DB; Factor SA; Freeman A; Hollars S; Wood-Siverio C -
DIGITIZED FEATURES OF PHASIC ACTIVITY OF SURFACE ANTERIOR TIBIALIS ELECTROMYOGRAPHY (EMG): VALIDATION BY CONSENSUS PANEL
Volume: 34 Page(s): A325 - A325
01/01/2011 Authors: Fairley J; Georgoulas G; Mehta N; Gray A; Trotti L; Wilson A; Greer S; Hollars S; Rye DB; Bliwise DL -
Dopaminergic Substrates Underlying Hypersomnia, Sleepiness, and REM Sleep Expression
Page(s): 61 - 71
01/01/2011 Authors: Rye DB; Freeman AAH -
DIFFERENTIAL ASSOCIATIONS BETWEEN LEVO-DOPA (L-DOPA) VS DOPAMINE AGONIST (DA) DOSE AND MAINTENANCE OF WAKEFULNESS TEST (MWT) MEASURES OF ALERTNESS IN IDIOPATHIC PARKINSON'S DISEASE (PD)
Volume: 34 Page(s): A221 - A221
01/01/2011 Authors: Bliwise DL; Trotti L; Wilson A; Greer S; Juncos J; Rye DB; Factor SA; Freeman A; Hollars S; Wood-Siverio C -
FEATURES OF POST-PREGNANCY RLS IN WOMEN WHOSE RLS WORSENED DURING PREGNANCY
Volume: 34 Page(s): A317 - A317
01/01/2011 Authors: Trotti L; Rye DB; Bliwise DL -
Phasic Electromyographic Metric detection based on wavelet analysis.
Mediterr Conf Control Automation
01/01/2011 Authors: Fairley JA; Georgoulas G; Stylios CD; Vachtsevanos G; Rye DB; Bliwise DL -
ELEVATED C-REACTIVE PROTEIN (CRP), BUT NOT INTERLEUKIN-6 (IL-6) OR TUMOR NECROSIS FACTOR ALPHA (TNF-A), IS ASSOCIATED WITH PERIODIC LIMB MOVEMENTS (PLMS)
Volume: 34 Page(s): A199 - A199
01/01/2011 Authors: Trotti L; Rye DB; De Staercke C; Hooper C; Quyyumi A; Bliwise DL -
BTBD9 EXPRESSION INFLUENCES BOTH DOPAMINE AND FERRITIN EXPRESSION
Volume: 34 Page(s): A11 - A11
01/01/2011 Authors: Freeman A; Pranski E; Betarbet R; Rye DB; Jinnah H; Sanyal S -
Restless legs syndrome.
Handb Clin Neurol Volume: 100 Page(s): 661 - 673
01/01/2011 Authors: Trotti LM; Rye DB -
Chronic interferon-alpha administration disrupts sleep continuity and depth in patients with hepatitis C: association with fatigue, motor slowing, and increased evening cortisol.
Biol Psychiatry Volume: 68 Page(s): 942 - 949
11/15/2010 Authors: Raison CL; Rye DB; Woolwine BJ; Vogt GJ; Bautista BM; Spivey JR; Miller AH -
Phasic muscle activity in sleep and clinical features of Parkinson disease.
Ann Neurol Volume: 68 Page(s): 353 - 359
09/01/2010 Authors: Bliwise DL; Trotti LM; Greer SA; Juncos JJ; Rye DB -
Wake promoting effects of cocaine and amphetamine-regulated transcript (CART).
Neuropeptides Volume: 44 Page(s): 241 - 246
06/01/2010 Authors: Keating GL; Kuhar MJ; Bliwise DL; Rye DB -
Seeing beyond one's nose: sleep disruption and excessive sleepiness accompany motor disability in the MPTP treated primate.
Exp Neurol Volume: 222 Page(s): 179 - 180
04/01/2010 Authors: Rye D -
Obstructive Sleep Apnea (OSA) in Idiopathic Intracranial Hypertension (IIH): A Prospective Study
Volume: 74 Page(s): A383 - A383
03/02/2010 Authors: Thurtell MJ; Bruce BB; Rye DB; Newman NJ; Biousse V -
Evidence continues to mount on the relationship of restless legs syndrome/ periodic limb movements in sleep to hypertension, cardiovascular disease, and stroke.
Sleep Volume: 33 Page(s): 287
03/01/2010 Authors: Walters AS; Rye DB -
Paradoxical sleep suppresses immediate early gene expression in the rodent suprachiasmatic nuclei.
Front Neurol Volume: 1 Page(s): 122
01/01/2010 Authors: Decker MJ; Rye DB; Lee S-Y; Strohl KP -
HOUR-TO-HOUR FLUCTUATIONS IN DIGIT SPAN (DS) PERFORMANCE IN PARKINSON'S DISEASE (PD): RELATION TO MWT-DEFINED ALERTNESS
SLEEP Volume: 33 Page(s): A282 - A282
01/01/2010 Authors: Wilson A; Hollars S; Greer S; Trotti L; Juncos J; Factor SA; Freeman A; Wood-Siverio C; Rye DB; Bliwise DL -
MWT, BUT NOT IMPAIRED OLFACTION, DIFFERENTIATES PARKINSON'S DISEASE (PD) FROM IDIOPATHIC REM BEHAVIOR DISORDER (RBD)
SLEEP Volume: 33 Page(s): A274 - A274
01/01/2010 Authors: Trotti L; Juncos J; Factor SA; Freeman A; Wilson A; Hollars S; Greer S; Wood-Siverio C; Rye DB; Bliwise DL -
ORTHOSTASIS ACROSS PARKINSONIAN SYNDROMES ASSOCIATED WITH LOWER MWT-DEFINED ALERTNESS
SLEEP Volume: 33 Page(s): A281 - A282
01/01/2010 Authors: Bliwise DL; Wilson A; Hollars S; Greer S; Trotti L; Juncos J; Factor SA; Freeman A; Wood-Siverio C; Rye DB -
PERIPHERAL NERVE HYPEREXCITABILITY IN RESTLESS LEG SYNDROME
Volume: 40 Page(s): 741 - 742
10/01/2009 Authors: Kesner V; Billars L; Rye D; Benatar M -
Correlates of PLMs variability over multiple nights and impact upon RLS diagnosis.
Sleep Med Volume: 10 Page(s): 668 - 671
06/01/2009 Authors: Trotti LM; Bliwise DL; Greer SA; Sigurdsson AP; Gudmundsdttir GB; Wessel T; Organisak LM; Sigthorsson T; Kristjansson K; Sigmundsson T -
Review of the relationship of restless legs syndrome and periodic limb movements in sleep to hypertension, heart disease, and stroke.
Sleep Volume: 32 Page(s): 589 - 597
05/01/2009 Authors: Walters AS; Rye DB -
Variant in the sequence of the LINGO1 gene confers risk of essential tremor.
Nat Genet Volume: 41 Page(s): 277 - 279
03/01/2009 Authors: Stefansson H; Steinberg S; Petursson H; Gustafsson O; Gudjonsdottir IH; Jonsdottir GA; Palsson ST; Jonsson T; Saemundsdottir J; Bjornsdottir G -
GAMBLING, SPENDING, AND BEING SEXY: AUGMENTATION SEVERITY AND IMPULSE CONTROL IN PATIENTS WITH RESTLESS LEGS SYNDROME (RLS)
Volume: 32 Page(s): A300 - A301
01/01/2009 Authors: Mian F; Rye DB; Bliwise D -
PHASIC ELECTROMYOGRAPHIC ACTIVITY IN PARKINSON'S DISEASE (PD) DISTINGUISHES RIGID (RD) FROM TREMOROUS (TR) SUBTYPES
Volume: 32 Page(s): A302 - A303
01/01/2009 Authors: Bliwise DL; Rye DB -
TIME UNDERESTIMATION IN A BEDSIDE EXAMINATION IS RELATED TO MWT-DEFINED ALERTNESS IN PARKINSONIAN PATIENTS
Volume: 32 Page(s): A246 - A246
01/01/2009 Authors: Wilson AG; Greer SA; Juncos JJ; Trotti L; Rye DB; Bliwise DL -
An update on the pathophysiology and genetics of restless legs syndrome.
Curr Neurol Neurosci Rep Volume: 8 Page(s): 281 - 287
07/01/2008 Authors: Trotti LM; Bhadriraju S; Rye DB -
Elevated PEM (phasic electromyographic metric) rates identify rapid eye movement behavior disorder patients on nights without behavioral abnormalities.
Sleep Volume: 31 Page(s): 853 - 857
06/01/2008 Authors: Bliwise DL; Rye DB -
High dose CART peptide induces abnormal EEG activity and behavioral seizures.
Neuropeptides Volume: 42 Page(s): 199 - 204
04/01/2008 Authors: Keating GL; Kuhar MJ; Rye DB -
Insomnia on dialysis nights: the beneficial effects of cool dialysate.
J Nephrol Volume: 21 Suppl 13 Page(s): S71 - S77
01/01/2008 Authors: Parker KP; Bailey JL; Rye DB; Bliwise DL; Van Someren EJW -
Phasic muscle activity during sleep in bilateral versus unilateral Parkinson's Disease (PD)
Volume: 31 Page(s): A280 - A280
01/01/2008 Authors: Bliwise DL; Rye DB -
Later treatment times favor the expression of restless legs syndrome independent of periodic limb movements in chronic hemodialysis
Volume: 31 Page(s): A273 - A274
01/01/2008 Authors: Parker KP; Bliwise DL; Rye DB -
Correlates of PLMS variability over multiple nights and impact upon RLS diagnosis
Volume: 31 Page(s): A331 - A331
01/01/2008 Authors: Trotti L; Bliwise DL; Greer SA; Sigurdsson AP; Wessel T; Organisak LM; Gudmundsdottir G; Kristjansson K; Sigmundsson T; Rye DB -
Higher heart rate and reduced heart rate variability persist during sleep in chronic fatigue syndrome: a population-based study.
Auton Neurosci Volume: 137 Page(s): 94 - 101
12/30/2007 Authors: Boneva RS; Decker MJ; Maloney EM; Lin J-M; Jones JF; Helgason HG; Heim CM; Rye DB; Reeves WC -
The metric properties of a novel non-motor symptoms scale for Parkinson's disease: Results from an international pilot study.
Mov Disord Volume: 22 Page(s): 1901 - 1911
10/15/2007 Authors: Chaudhuri KR; Martinez-Martin P; Brown RG; Sethi K; Stocchi F; Odin P; Ondo W; Abe K; Macphee G; Macmahon D -
A genetic risk factor for periodic limb movements in sleep.
N Engl J Med Volume: 357 Page(s): 639 - 647
08/16/2007 Authors: Stefansson H; Rye DB; Hicks A; Petursson H; Ingason A; Thorgeirsson TE; Palsson S; Sigmundsson T; Sigurdsson AP; Eiriksdottir I -
Prevalence of nonmotor symptoms in Parkinson's disease in an international setting; study using nonmotor symptoms questionnaire in 545 patients.
Mov Disord Volume: 22 Page(s): 1623 - 1629
08/15/2007 Authors: Martinez-Martin P; Schapira AHV; Stocchi F; Sethi K; Odin P; MacPhee G; Brown RG; Naidu Y; Clayton L; Abe K -
Diagnostic standards for dopaminergic augmentation of restless legs syndrome: report from a World Association of Sleep Medicine-International Restless Legs Syndrome Study Group consensus conference at the Max Planck Institute.
Sleep Med Volume: 8 Page(s): 520 - 530
08/01/2007 Authors: Garca-Borreguero D; Allen RP; Kohnen R; Hgl B; Trenkwalder C; Oertel W; Hening WA; Paulus W; Rye D; Walters A -
Comment on Shpirer et al. ("Excessive daytime sleepiness in patients with Parkinson's disease: a polysomnographic study").
Mov Disord Volume: 22 Page(s): 1520
07/30/2007 Authors: Trotti LM; Rye DB; Bliwise DL -
Lowering dialysate temperature improves sleep and alters nocturnal skin temperature in patients on chronic hemodialysis.
J Sleep Res Volume: 16 Page(s): 42 - 50
03/01/2007 Authors: Parker KP; Bailey JL; Rye DB; Bliwise DL; Van Someren EJW -
Augmentation as a treatment complication of restless legs syndrome: concept and management.
Volume: 22 Suppl 18 Page(s): S476 - S484
01/01/2007 Authors: Garca-Borreguero D; Allen RP; Benes H; Earley C; Happe S; Hgl B; Kohnen R; Paulus W; Rye D; Winkelmann J -
Genetics of restless legs syndrome (RLS): State-of-the-art and future directions.
Volume: 22 Suppl 18 Page(s): S449 - S458
01/01/2007 Authors: Winkelmann J; Polo O; Provini F; Nevsimalova S; Kemlink D; Sonka K; Hgl B; Poewe W; Stiasny-Kolster K; Oertel W -
Pictorial phenotype of rest-less legs syndrome (RLS)
Volume: 30 Page(s): A290 - A290
01/01/2007 Authors: Mummaneni R; Rye D; Bliwise D -
Functional anatomy and treatment of RLS/PLMS emerging after spinal cord lesions
Volume: 30 Page(s): A306 - A306
01/01/2007 Authors: Trotti L; Rye D -
Double-blind, placebo (PLO)-controlled, polysomnographic randomized clinical trial (RCT) of valerian (VAL) for sleep in parkinson's disease (PD)
Volume: 30 Page(s): A41 - A41
01/01/2007 Authors: Bliwise D; Saunders D; Wood-Siverio C; Greer S; Pour Ansari F; Rye D; Hitchcock S; Decker M -
Elevated PEM (phasic electromyographic metric) rates in rapid eye movement behavior disorder (REMBD) on nights without behavioral abnormalities
Volume: 30 Page(s): A301 - A302
01/01/2007 Authors: Bliwise D; Rye D -
Sleep characteristics of persons with chronic fatigue syndrome and non-fatigued controls: results from a population-based study.
BMC Neurol Volume: 6 Page(s): 41
11/16/2006 Authors: Reeves WC; Heim C; Maloney EM; Youngblood LS; Unger ER; Decker MJ; Jones JF; Rye DB -
Restless legs syndrome: revisiting the dopamine hypothesis from the spinal cord perspective.
Neurology Volume: 67 Page(s): 125 - 130
07/11/2006 Authors: Clemens S; Rye D; Hochman S -
International multicenter pilot study of the first comprehensive self-completed nonmotor symptoms questionnaire for Parkinson's disease: the NMSQuest study.
Mov Disord Volume: 21 Page(s): 916 - 923
07/01/2006 Authors: Chaudhuri KR; Martinez-Martin P; Schapira AHV; Stocchi F; Sethi K; Odin P; Brown RG; Koller W; Barone P; MacPhee G -
Regulation of CART mRNA in the rat nucleus accumbens via D3 dopamine receptors.
Neuropharmacology Volume: 50 Page(s): 858 - 864
06/01/2006 Authors: Hunter RG; Jones D; Vicentic A; Hue G; Rye D; Kuhar MJ -
Lesions in monkey globus pallidus externus exacerbate parkinsonian symptoms.
Exp Neurol Volume: 199 Page(s): 446 - 453
06/01/2006 Authors: Zhang J; Russo GS; Mewes K; Rye DB; Vitek JL -
What should we be measuring? Defining the "P" in PLMS.
Sleep Volume: 29 Page(s): 741 - 742
06/01/2006 Authors: Rye DB -
Effect of dopamine-3 receptor knockout and iron deficiency on pain threshold using a mouse model
Volume: 20 Page(s): A777 - A777
03/06/2006 Authors: Weissmiller SJ; Hue G; Rye D -
Excessive daytime sleepiness and unintended sleep in Parkinson's disease.
Curr Neurol Neurosci Rep Volume: 6 Page(s): 169 - 176
03/01/2006 Authors: Rye DB -
Quantification of electromyographic activity during sleep: a phasic electromyographic metric.
J Clin Neurophysiol Volume: 23 Page(s): 59 - 67
02/01/2006 Authors: Bliwise DL; He L; Ansari FP; Rye DB -
Prolonged assessment of sleep and daytime sleepiness in unrestrained Macaca mulatta.
Sleep Volume: 29 Page(s): 221 - 231
02/01/2006 Authors: Daley JT; Turner RS; Freeman A; Bliwise DL; Rye DB -
Ropinirole treatment effectively relieves subjective and motor symptoms of restless legs syndrome (RLS), providing sleep benefits
Volume: 29 Page(s): A288 - A288
01/01/2006 Authors: Rye DB; Watson C -
Neonatal intermittent hypoxia in rats induces sex-specific increases in dopamine levels in the nucleus accumbens
Volume: 29 Page(s): A26 - A26
01/01/2006 Authors: Hue G; Keating G; Miller RD; Rye DB; Decker MJ -
Cart peptide promotes wake and seizure activity in the rat
Volume: 29 Page(s): A22 - A22
01/01/2006 Authors: Keating GL; Kuhar MJ; Vicentic A; Rye DB -
In vivo diurnal rhythm of dopamine measured in the putamen of non-human primates
Volume: 29 Page(s): A69 - A69
01/01/2006 Authors: Freeman A; Morales JC; Beck JM; Knowlson K; Justice JB; Howell LL; Rye DB -
Characteristics of idiopathic REM sleep behavior disorder and that associated with MSA and PD.
Neurology Volume: 65 Page(s): 247 - 252
07/26/2005 Authors: Iranzo A; Santamara J; Rye DB; Valldeoriola F; Mart MJ; Muoz E; Vilaseca I; Tolosa E -
Polysomnographic measures of nocturnal sleep in patients on chronic, intermittent daytime haemodialysis vs those with chronic kidney disease.
Nephrol Dial Transplant Volume: 20 Page(s): 1422 - 1428
07/01/2005 Authors: Parker KP; Bliwise DL; Bailey JL; Rye DB -
CART peptide identification in monkey and human CSF
Volume: 19 Page(s): A509 - A509
03/04/2005 Authors: Vicentic A; Dominguez G; Rye D; Kuhar M -
Randomized, double-blind, placebo-controlled, short-term trial of ropinirole in restless legs syndrome.
Sleep Med Volume: 6 Page(s): 141 - 147
03/01/2005 Authors: Bliwise DL; Freeman A; Ingram CD; Rye DB; Chakravorty S; Watts RL -
An item response analysis of the international restless legs syndrome study group rating scale for restless legs syndrome.
Sleep Med Volume: 6 Page(s): 131 - 139
03/01/2005 Authors: Wunderlich GR; Evans KR; Sills T; Pollentier S; Reess J; Allen RP; Hening W; Walters AS; International Restless Legs Syndrome Study Group -
Reduced extracellular dopamine and increased responsiveness to novelty: neurochemical and behavioral sequelae of intermittent hypoxia.
Sleep Volume: 28 Page(s): 169 - 176
02/01/2005 Authors: Decker MJ; Jones KA; Solomon IG; Keating GL; Rye DB -
Population-based confirmation of the 12q RLS locus in Iceland
Volume: 28 Page(s): A277 - A278
01/01/2005 Authors: Rye DB; Hicks AA; Kristjansson K; Sigmundsson T; Sigurdsson A; Hakonarson H; Stefansson H; Bliwise D; Gulcher J; Stefensson K -
Ropinirole decreases bedtime periodic leg movements in patients with RLS: Results of a 12-week US study
Volume: 28 Page(s): A270 - A270
01/01/2005 Authors: Rye D; Allen R; Carson SW; Ritchie S -
Nightly variability in perceived sleep quality of Parkinson Disease (PD) patients is reflected in polysomnography
Volume: 28 Page(s): A286 - A286
01/01/2005 Authors: Saunders DD; Hitchcock SE; Greer SA; Ansari FP; Wood-Siverio C; Decker MJ; Rye DB; Bliwise DL -
Sleep disordered breathing (SDB) in Parkinsons Disease (PD)
Volume: 28 Page(s): A286 - A287
01/01/2005 Authors: Hitchcock SE; Greer SA; Ansari F; Wood-Siverio C; Decker MJ; Rye DB; Bliwise DL -
Population-based confirmation of the 12q RLS locus in Iceland
Volume: 20 Page(s): S34 - S34
01/01/2005 Authors: Hicks AA; Rye DB; Kristjansson K; Sigmundsson T; Sigurdsson AP; Eiriksdottir I -
Relief in sight for restless legs syndrome.
Neurology Volume: 63 Page(s): 2213 - 2214
12/28/2004 Authors: Rye DB -
Parkinson's disease and sleep - Introduction
NEUROLOGY Volume: 63 Page(s): S1 - S1
10/26/2004 Authors: Tolosa E; Barone P; Rye DB -
The two faces of Eve: dopamine's modulation of wakefulness and sleep.
Neurology Volume: 63 Page(s): S2 - S7
10/26/2004 Authors: Rye DB -
An algorithm for the management of restless legs syndrome.
Mayo Clin Proc Volume: 79 Page(s): 916 - 922
07/01/2004 Authors: Silber MH; Ehrenberg BL; Allen RP; Buchfuhrer MJ; Earley CJ; Hening WA; Rye DB; Medical Advisory Board of the Restless Legs Syndrome Foundation -
Parkinson's disease and RLS: the dopaminergic bridge.
Volume: 5 Page(s): 317 - 328
05/01/2004 Authors: Rye DB -
Nocturnal sleep, daytime sleepiness, and quality of life in stable patients on hemodialysis.
Health Qual Life Outcomes Volume: 1 Page(s): 68
11/21/2003 Authors: Parker KP; Kutner NG; Bliwise DL; Bailey JL; Rye DB -
Where you least expect it: dopamine in the pons and modulation of sleep and REM-sleep.
Sleep Volume: 26 Page(s): 788 - 789
11/01/2003 Authors: Keating GL; Rye DB -
Assessment of sleepiness and unintended sleep in Parkinson's disease patients taking dopamine agonists.
Sleep Med Volume: 4 Page(s): 275 - 280
07/01/2003 Authors: Roth T; Rye DB; Borchert LD; Bartlett C; Bliwise DL; Cantor C; Gorell JM; Hubble JP; Musch B; Olanow CW -
Sleep disturbances in a rat model of chronic renal failure
Volume: 26 Page(s): A68 - A68
05/15/2003 Authors: Keating GL; Bailey JL; Parker KP; Rye DB -
Influence of PLMS on scoring phasic leg muscle activity
Volume: 26 Page(s): A344 - A344
05/15/2003 Authors: Bliwise DL; Ansari FP; Rye DB; He L -
Operationalization of "sleep benefit" (SB) in Parkinson's disease (PD)
Volume: 26 Page(s): A345 - A345
05/15/2003 Authors: Syed BH; Koury D; Ansari FP; Bliwise DL; Rye DB -
Sleepiness and Unintended Sleep in Parkinson's Disease.
Curr Treat Options Neurol Volume: 5 Page(s): 231 - 239
05/01/2003 Authors: Rye DB -
Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs syndrome.
Sleep Med Volume: 4 Page(s): 121 - 132
03/01/2003 Authors: Walters AS; LeBrocq C; Dhar A; Hening W; Rosen R; Allen RP; Trenkwalder C; International Restless Legs Syndrome Study Group -
Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institutes of Health.
Sleep Med Volume: 4 Page(s): 101 - 119
03/01/2003 Authors: Allen RP; Picchietti D; Hening WA; Trenkwalder C; Walters AS; Montplaisi J; Restless Legs Syndrome Diagnosis and Epidemiology workshop at the National Institutes of Health; International Restless Legs Syndrome Study Group -
Time to focus on the locus.
Arch Neurol Volume: 60 Page(s): 320
03/01/2003 Authors: Rye D; DeLong MR -
Daytime sleepiness in stable hemodialysis patients.
Am J Kidney Dis Volume: 41 Page(s): 394 - 402
02/01/2003 Authors: Parker KP; Bliwise DL; Bailey JL; Rye DB -
REM sleep behavior disorder and SCA-3 (Machado-Joseph disease).
Neurology Volume: 60 Page(s): 148
01/14/2003 Authors: Syed BH; Rye DB; Singh G -
Narcolepsy in the older adult: epidemiology, diagnosis and management.
Drugs Aging Volume: 20 Page(s): 361 - 376
01/01/2003 Authors: Chakravorty SS; Rye DB -
Episodic neonatal hypoxia evokes executive dysfunction and regionally specific alterations in markers of dopamine signaling.
Neuroscience Volume: 117 Page(s): 417 - 425
01/01/2003 Authors: Decker MJ; Hue GE; Caudle WM; Miller GW; Keating GL; Rye DB -
Restless legs syndrome and periodic limb movement disorder.
Nurs Clin North Am Volume: 37 Page(s): 655 - 673
12/01/2002 Authors: Parker KP; Rye DB -
Neonatal intermittent hypoxia impairs dopamine signaling and executive functioning.
Sleep Breath Volume: 6 Page(s): 205 - 210
12/01/2002 Authors: Decker MJ; Rye DB -
Modulation of normal and pathologic motoneuron activity during sleep: insights from the neurology clinic, Parkinson's disease, and comments on parkinsonian-related sleepiness.
Sleep Med Volume: 3 Suppl Page(s): S43 - S49
11/01/2002 Authors: Rye DB -
Microdialysis probes: Opening a window on the sleeping but still behaving brain
NEUROLOGY Volume: 59 Page(s): 1123 - 1123
10/22/2002 Authors: Rye DB -
Trinucleotide repeat counts and self-reported daytime sleepiness in myotonic dystrophy
SLEEP Volume: 25 Page(s): A257 - A258
04/15/2002 Authors: Syed BH; Glass JD; Bliwise DL; Rye DB -
The effects of cool dialysate on body temperature and sleep in patients on chronic hemodialysis
SLEEP Volume: 25 Page(s): A110 - A111
04/15/2002 Authors: Parker KP; Bailey JL; Rye DB; Bliwise DL; Vena C -
Validation of a commercially available rodent polysomnographic scoring algorithm
SLEEP Volume: 25 Page(s): A507 - A508
04/15/2002 Authors: Keating GL; Decker MJ; Rye DB -
Unintended sleep episodes in Parkinson's disease patients receiving dopaminergic agents
SLEEP Volume: 25 Page(s): A372 - A373
04/15/2002 Authors: Borchert LD; Roth T; Bliwise DL; Cantor C; Gorell JM; Hubble JP; Pollak C; Rye DB; Stern MB; Watts RL -
Neonatal intermittent hypoxia induces hypodopaminergic activity in the striatum, decreased wakefulness, hyperactivity, and working memory impairment.
SLEEP Volume: 25 Page(s): A349 - A349
04/15/2002 Authors: Decker MJ; Caudle WM; Hue GE; Miller GW; Rye DB -
Emerging views of dopamine in modulating sleep/wake state from an unlikely source: PD.
Neurology Volume: 58 Page(s): 341 - 346
02/12/2002 Authors: Rye DB; Jankovic J -
Greater daytime sleepiness in subcortical stroke relative to Parkinson's disease and Alzheimer's disease.
J Geriatr Psychiatry Neurol Volume: 15 Page(s): 61 - 67
01/01/2002 Authors: Bliwise DL; Rye DB; Dihenia B; Gurecki P -
Polymorphisms in hypocretin/orexin pathway genes and narcolepsy.
Neurology Volume: 57 Page(s): 1896 - 1899
11/27/2001 Authors: Olafsdttir BR; Rye DB; Scammell TE; Matheson JK; Stefnsson K; Gulcher JR -
Nigrostriatal collaterals to thalamus degenerate in parkinsonian animal models.
Ann Neurol Volume: 50 Page(s): 321 - 329
09/01/2001 Authors: Freeman A; Ciliax B; Bakay R; Daley J; Miller RD; Keating G; Levey A; Rye D -
Solving the mysteries of narcolepsy: the hypocretin story.
Neurology Volume: 56 Page(s): 1616 - 1618
06/26/2001 Authors: Silber MH; Rye DB -
Ropinirole for restless legs syndrome (RLS): An open-label and double blind placebo controlled study
NEUROLOGY Volume: 56 Page(s): A5 - A5
04/24/2001 Authors: Freeman A; Rye DB; Bliwise D; Chakravorty S; Krulewicz S; Watts RL -
Sleep/wake patterns of patients on chronic hemodialysis via ambulatory polysomnography
SLEEP Volume: 24 Page(s): A36 - A36
04/15/2001 Authors: Parker KP; Bliwise DL; Rye DB; Bailey J -
Duration of prescribed hemodialysis treatment time predicts daytime sleepiness levels
SLEEP Volume: 24 Page(s): A36 - A37
04/15/2001 Authors: Parker KP; Bliwise DL; Rye DB; Bailey J -
Functional organization of brainstem-basal ganglia interactions as viewed from the pedunculopontine region
Page(s): 175 - 188
01/01/2001 Authors: Keating GL; Rye DB -
Intradialytic subjective sleepiness and oral body temperature.
Sleep Volume: 23 Page(s): 887 - 891
11/01/2000 Authors: Parker KP; Bliwise DL; Rye DB; De A -
Inter-rater reliability for identification of REM sleep in Parkinson's disease.
Sleep Volume: 23 Page(s): 671 - 676
08/01/2000 Authors: Bliwise DL; Willians ML; Irbe D; Ansari FP; Rye DB -
Dopamine D(5) receptor immunolocalization in rat and monkey brain.
Synapse Volume: 37 Page(s): 125 - 145
08/01/2000 Authors: Ciliax BJ; Nash N; Heilman C; Sunahara R; Hartney A; Tiberi M; Rye DB; Caron MG; Niznik HB; Levey AI -
Ropinirole for restless legs syndrome (RLS)
NEUROLOGY Volume: 54 Page(s): A19 - A19
04/11/2000 Authors: Freeman A; Rye DB; Bliwise D; Krulewicz S; Watts RL -
FAST TRACK: daytime sleepiness in Parkinson's disease.
J Sleep Res Volume: 9 Page(s): 63 - 69
03/01/2000 Authors: Rye DB; Bliwise DL; Dihenia B; Gurecki P -
Falling asleep at the wheel: motor vehicle mishaps in people taking pramipexole and ropinirole.
Neurology Volume: 54 Page(s): 276 - 277
01/11/2000 Authors: Rye DB; Bliwise DL -
Falling asleep at the wheel: motor vehicle mishaps in people taking pramipexole and ropinirole.
Neurology Volume: 54 Page(s): 274
01/11/2000 Authors: Olanow CW; Schapira AH; Roth T -
Hemodialysis disrupts basic sleep regulatory mechanisms: building hypotheses.
Nurs Res Volume: 49 Page(s): 327 - 332
01/01/2000 Authors: Parker KP; Bliwise DL; Rye DB -
Juvenile Parkinson's disease with REM sleep behavior disorder, sleepiness, and daytime REM onset.
Neurology Volume: 53 Page(s): 1868 - 1870
11/10/1999 Authors: Rye DB; Johnston LH; Watts RL; Bliwise DL -
Amelioration of sensory limb discomfort of restless legs syndrome by pallidotomy.
Ann Neurol Volume: 46 Page(s): 800 - 801
11/01/1999 Authors: Rye DB; DeLong MR -
Tracking neural pathways with MRI.
Trends Neurosci Volume: 22 Page(s): 373 - 374
09/01/1999 Authors: Rye DB -
Nuclear and neuropil aggregates in Huntington's disease: relationship to neuropathology.
J Neurosci Volume: 19 Page(s): 2522 - 2534
04/01/1999 Authors: Gutekunst CA; Li SH; Yi H; Mulroy JS; Kuemmerle S; Jones R; Rye D; Ferrante RJ; Hersch SM; Li XJ -
Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease.
Exp Neurol Volume: 156 Page(s): 138 - 148
03/01/1999 Authors: Miller GW; Erickson JD; Perez JT; Penland SN; Mash DC; Rye DB; Levey AI -
The pathophysiology of REM-sleep behavior disorder - Reply
SLEEP Volume: 21 Page(s): 446 - 449
08/01/1998 Authors: Rye DB -
Microelectrode-guided pallidotomy: technical approach and its application in medically intractable Parkinson's disease.
J Neurosurg Volume: 88 Page(s): 1027 - 1043
06/01/1998 Authors: Vitek JL; Bakay RA; Hashimoto T; Kaneoke Y; Mewes K; Zhang JY; Rye D; Starr P; Baron M; Turner R -
Presentation of narcolepsy after 40.
Neurology Volume: 50 Page(s): 459 - 465
02/01/1998 Authors: Rye DB; Dihenia B; Weissman JD; Epstein CM; Bliwise DL -
Reversal of atypical depression, sleepiness, and REM-sleep propensity in narcolepsy with bupropion.
Depress Anxiety Volume: 7 Page(s): 92 - 95
01/01/1998 Authors: Rye DB; Dihenia B; Bliwise DL -
Distribution of muscarinic cholinergic receptor proteins m1 to m4 in area 17 of normal and monocularly deprived rhesus monkeys.
J Comp Neurol Volume: 388 Page(s): 130 - 145
11/10/1997 Authors: Tigges M; Tigges J; Rees H; Rye D; Levey AI -
Frequency of multiple sleep onset REM periods in "control" subjects.
Sleep Volume: 20 Page(s): 813 - 814
09/01/1997 Authors: Rye DB; Bliwise DL -
Contributions of the pedunculopontine region to normal and altered REM sleep.
Sleep Volume: 20 Page(s): 757 - 788
09/01/1997 Authors: Rye DB -
Ultrastructural study of cholinergic and noncholinergic neurons in the pars compacta of the rat pedunculopontine tegmental nucleus.
J Comp Neurol Volume: 382 Page(s): 285 - 301
06/09/1997 Authors: Steininger TL; Wainer BH; Rye DB -
Serotonergic dorsal raphe nucleus projections to the cholinergic and noncholinergic neurons of the pedunculopontine tegmental region: a light and electron microscopic anterograde tracing and immunohistochemical study.
J Comp Neurol Volume: 382 Page(s): 302 - 322
06/09/1997 Authors: Steininger TL; Wainer BH; Blakely RD; Rye DB -
Presenilin-1 protein expression in familial and sporadic Alzheimer's disease.
Ann Neurol Volume: 41 Page(s): 742 - 753
06/01/1997 Authors: Levey AI; Heilman CJ; Lah JJ; Nash NR; Rees HD; Wakai M; Mirra SS; Rye DB; Nochlin D; Bird TD -
Immunochemical analysis of dopamine transporter protein in Parkinson's disease.
Ann Neurol Volume: 41 Page(s): 530 - 539
04/01/1997 Authors: Miller GW; Staley JK; Heilman CJ; Perez JT; Mash DC; Rye DB; Levey AI -
Neurobiology of disruptive nocturnal behavior - Reply
JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY Volume: 9 Page(s): 102 - 102
04/01/1996 Authors: Bliwise DL; Rye DB -
COMPARISON OF PHYSIOLOGICAL MAPPING, MAGNETIC-RESONANCE-IMAGING, AND HISTOLOGIC LESION IN A PATIENT WHO UNDERWENT MICROELECTRODE-GUIDED PALLIDOTOMY FOR PARKINSONS-DISEASE
Volume: 38 Page(s): 298 - 298
08/01/1995 Authors: DELONG MR; VITEK JL; RYE D; SHEPPARD S; BAKAY RAE; KANEOKE Y; HASHIMOTO T; BARON M; TURNER R -
Disruptive nocturnal behavior in Parkinson's disease and Alzheimer's disease.
J Geriatr Psychiatry Neurol Volume: 8 Page(s): 107 - 110
04/01/1995 Authors: Bliwise DL; Watts RL; Watts N; Rye DB; Irbe D; Hughes M -
Identification and characterization of antidepressant-sensitive serotonin transporter proteins using site-specific antibodies.
J Neurosci Volume: 15 Page(s): 1261 - 1274
02/01/1995 Authors: Qian Y; Melikian HE; Rye DB; Levey AI; Blakely RD -
Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies.
Proc Natl Acad Sci U S A Volume: 90 Page(s): 8861 - 8865
10/01/1993 Authors: Levey AI; Hersch SM; Rye DB; Sunahara RK; Niznik HB; Kitt CA; Price DL; Maggio R; Brann MR; Ciliax BJ -
The distribution of Alz-50 immunoreactivity in the normal human brain.
Neuroscience Volume: 56 Page(s): 109 - 127
09/01/1993 Authors: Rye DB; Leverenz J; Greenberg SG; Davies P; Saper CB -
MOLECULAR PHARMACOLOGY OF DOPAMINERGIC AND CHOLINERGIC SYSTEMS IN THE BASAL GANGLIA
ANNALS OF NEUROLOGY Volume: 34 Page(s): 246 - 247
08/01/1993 Authors: LEVEY AI; HERSCH S; CILIAX B; RYE DB -
Differences in the retinohypothalamic tract in albino Lewis versus brown Norway rat strains.
Neuroscience Volume: 54 Page(s): 11 - 14
05/01/1993 Authors: Steininger TL; Rye DB; Gilliland MA; Wainer BH; Benca RM -
Afferent projections to the cholinergic pedunculopontine tegmental nucleus and adjacent midbrain extrapyramidal area in the albino rat. I. Retrograde tracing studies.
J Comp Neurol Volume: 321 Page(s): 515 - 543
07/22/1992 Authors: Steininger TL; Rye DB; Wainer BH -
Cortical asymmetry of REM sleep EEG following unilateral pontine hemorrhage.
Neurology Volume: 41 Page(s): 598 - 601
04/01/1991 Authors: Kushida CA; Rye DB; Nummy D; Milton JG; Spire JP; Rechtschaffen A -
Cholinergic vs. noncholinergic efferents from the mesopontine tegmentum to the extrapyramidal motor system nuclei.
J Comp Neurol Volume: 275 Page(s): 469 - 492
09/22/1988 Authors: Lee HJ; Rye DB; Hallanger AE; Levey AI; Wainer BH -
ALZ-50 IMMUNOREACTIVE STAINING IN NORMAL AND ALZHEIMER BRAIN
ANNALS OF NEUROLOGY Volume: 24 Page(s): 124 - 124
07/01/1988 Authors: SAPER CB; RYE DB; DAVIES P -
Medullary and spinal efferents of the pedunculopontine tegmental nucleus and adjacent mesopontine tegmentum in the rat.
J Comp Neurol Volume: 269 Page(s): 315 - 341
03/15/1988 Authors: Rye DB; Lee HJ; Saper CB; Wainer BH -
The origins of cholinergic and other subcortical afferents to the thalamus in the rat.
J Comp Neurol Volume: 262 Page(s): 105 - 124
08/01/1987 Authors: Hallanger AE; Levey AI; Lee HJ; Rye DB; Wainer BH -
Pedunculopontine tegmental nucleus of the rat: cytoarchitecture, cytochemistry, and some extrapyramidal connections of the mesopontine tegmentum.
J Comp Neurol Volume: 259 Page(s): 483 - 528
05/22/1987 Authors: Rye DB; Saper CB; Lee HJ; Wainer BH -
Substance P-containing terminals in synaptic contact with cholinergic neurons in the neostriatum and basal forebrain: a double immunocytochemical study in the rat.
Brain Res Volume: 397 Page(s): 279 - 289
11/12/1986 Authors: Bolam JP; Ingham CA; Izzo PN; Levey AI; Rye DB; Smith AD; Wainer BH -
Colocalization of gamma-aminobutyric acid and acetylcholinesterase in rodent cortical neurons.
Neuroscience Volume: 19 Page(s): 763 - 769
11/01/1986 Authors: Hallanger AE; Wainer BH; Rye DB -
A light and electron microscopic procedure for sequential double antigen localization using diaminobenzidine and benzidine dihydrochloride.
J Histochem Cytochem Volume: 34 Page(s): 1449 - 1457
11/01/1986 Authors: Levey AI; Bolam JP; Rye DB; Hallanger AE; Demuth RM; Mesulam MM; Wainer BH -
Colocalization of atriopeptin-like immunoreactivity with choline acetyltransferase- and substance P-like immunoreactivity in the pedunculopontine and laterodorsal tegmental nuclei in the rat.
Brain Res Volume: 382 Page(s): 163 - 168
09/10/1986 Authors: Standaert DG; Saper CB; Rye DB; Wainer BH -
HEMISPHERECTOMY IN INFANCY ENLARGES THE DISTRIBUTION OF MOTOR NEURONS IN THE REMAINING CEREBRAL HEMISPHERE
ANNALS OF NEUROLOGY Volume: 20 Page(s): 418 - 418
09/01/1986 Authors: HUTTENLOCHER PR; RAICHELSON RM; RYE DB; WAINER BH -
Cholinergic innervation displays strikingly different laminar preferences in several cortical areas.
Neurosci Lett Volume: 64 Page(s): 102 - 108
02/14/1986 Authors: Lysakowski A; Wainer BH; Rye DB; Bruce G; Hersh LB -
Stabilization of TMB reaction product for electron microscopic retrograde and anterograde fiber tracing.
Brain Res Bull Volume: 14 Page(s): 277 - 281
03/01/1985 Authors: Lemann W; Saper CB; Rye DB; Wainer BH -
Cholinergic and non-cholinergic septohippocampal pathways.
Neurosci Lett Volume: 54 Page(s): 45 - 52
02/28/1985 Authors: Wainer BH; Levey AI; Rye DB; Mesulam MM; Mufson EJ -
Stabilization of the tetramethylbenzidine (TMB) reaction product: application for retrograde and anterograde tracing, and combination with immunohistochemistry.
J Histochem Cytochem Volume: 32 Page(s): 1145 - 1153
11/01/1984 Authors: Rye DB; Saper CB; Wainer BH -
Cortical projections arising from the basal forebrain: a study of cholinergic and noncholinergic components employing combined retrograde tracing and immunohistochemical localization of choline acetyltransferase.
Neuroscience Volume: 13 Page(s): 627 - 643
11/01/1984 Authors: Rye DB; Wainer BH; Mesulam MM; Mufson EJ; Saper CB -
Choline acetyltransferase-immunoreactive neurons intrinsic to rodent cortex and distinction from acetylcholinesterase-positive neurons.
Neuroscience Volume: 13 Page(s): 341 - 353
10/01/1984 Authors: Levey AI; Wainer BH; Rye DB; Mufson EJ; Mesulam MM -
Retrograde horseradish peroxidase tracing combined with localization of choline acetyltransferase immunoreactivity.
J Histochem Cytochem Volume: 32 Page(s): 439 - 443
04/01/1984 Authors: Wainer BH; Rye DB -
Immunochemical studies of bovine and human choline-O-acetyltransferase using monoclonal antibodies.
J Neurochem Volume: 39 Page(s): 1652 - 1659
12/01/1982 Authors: Levey AI; Rye DB; Wainer BH