Allan Levey MD/PhD
- Department of Neurology
Professor
- (404) 727-7220
- alevey@emory.edu
-
Goizueta Institute @ Emory Brain Health
6 Executive Park Drive NE, Suite 250
Academic Appointment
- Professor of Pharmacology, Emory University
- Professor of Psychiatry & Behavioral Sciences, Emory University
- Robert W. Woodruff Professor of Neurology, Emory University
Education
Degrees
- M.D. with Honors from University of Chicago
- B.S. with Honors from University of Michigan
- PhD from University of Chicago
Research
Focus
- Dementia and Neurodegenerative Diseases Molecular Pharmacology of Cholinergic Systems
Publications
-
Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open-label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU trial.
Lancet Neurol Volume: 24 Page(s): 316 - 330
04/01/2025 Authors: Bateman RJ; Li Y; McDade EM; Llibre-Guerra JJ; Clifford DB; Atri A; Mills SL; Santacruz AM; Wang G; Supnet C -
Longitudinal analysis of a dominantly inherited Alzheimer disease mutation carrier protected from dementia.
Nat Med Volume: 31 Page(s): 1267 - 1275
04/01/2025 Authors: Llibre-Guerra JJ; Fernandez MV; Joseph-Mathurin N; Bian S; Carter K; Li Y; Aschenbrenner AJ; Pottier C; Sigurdson W; McDade E -
Proteomic Subtyping of Alzheimer's Disease CSF links Blood-Brain Barrier Dysfunction to Reduced levels of Tau and Synaptic Biomarkers.
03/15/2025 Authors: Bangs MC; Gadhavi J; Carter EK; Ping L; Duong DM; Dammer EB; Wu F; Shantaraman A; Fox EJ; Johnson ECB -
Correlation between changes in apathy and cognition in Alzheimer's disease associated apathy: Analysis of the Apathy in Dementia Methylphenidate Trial 2 (ADMET 2).
Int Psychogeriatr Volume: 37 Page(s): 100012
03/01/2025 Authors: Sankhe K; Tumati S; Perin J; Rivet L; Vieira D; Rosenberg PB; Herrmann N; Shade D; Lerner AJ; Padala PR -
Probing locus coeruleus functional network in healthy aging and its association with Alzheimer's disease biomarkers using pupillometry.
Alzheimers Res Ther Volume: 17 Page(s): 53
02/27/2025 Authors: Wu J; Toporek A; Lin Q; Goldstein FC; Loring DW; Kelberman MA; Weinshenker D; Levey AI; Lah JJ; Qiu D -
Plasma Biomarkers for Cerebral Amyloid Angiopathy and Implications for Amyloid-Related Imaging Abnormalities: A Comprehensive Review.
J Clin Med Volume: 14
02/07/2025 Authors: Sin M-K; Dage JL; Nho K; Dowling NM; Seyfried NT; Bennett DA; Levey AI; Ahmed A -
Safety and efficacy of long-term gantenerumab treatment in dominantly inherited Alzheimer's disease: an open label extension of the phase 2/3 multicentre, randomised, double-blind, placebo-controlled platform DIAN-TU Trial.
medRxiv
01/29/2025 Authors: Bateman RJ; Li Y; McDade EM; Llibre-Guerra JJ; Clifford DB; Atri A; Mills SL; Santacruz AM; Wang G; Supnet C -
Integrative multiomics reveals common endotypes across PSEN1, PSEN2, and APP mutations in familial Alzheimer's disease.
Alzheimers Res Ther Volume: 17 Page(s): 5
01/04/2025 Authors: Valdes P; Caldwell AB; Liu Q; Fitzgerald MQ; Ramachandran S; Karch CM; Dominantly Inherited Alzheimer Network (DIAN); Galasko DR; Yuan SH; Wagner SL -
Stratifying risk of Alzheimer's disease in healthy middle-aged individuals with machine learning.
Brain Commun Volume: 7 Page(s): fcaf121
01/01/2025 Authors: Tandon R; Zhao L; Watson CM; Sarkar N; Elmor M; Heilman C; Sanders K; Hales CM; Yang H; Loring DW -
Feasibility of assessing cognitive impairment via distributed camera network and privacy-preserving edge computing.
Alzheimers Dement (Amst) Volume: 17 Page(s): e70085
01/01/2025 Authors: Hegde C; Kiarashi Y; Levey AI; Rodriguez AD; Kwon H; Clifford GD -
Glymphatic system in neurological disorders and implications for brain health.
Front Neurol Volume: 16 Page(s): 1543725
01/01/2025 Authors: Corbali O; Levey AI -
CSF proteomics reveals changes in myelin and synaptic biology after Spectris treatment.
Alzheimers Dement (N Y) Volume: 11 Page(s): e70051
01/01/2025 Authors: Hajs M; Pandey K; Singer AC; Duong D; Bitarafan S; Shpokayte M; Malchano Z; Kern R; Lah JJ; Levey AI -
Brain derived -interferon is a potential player in Alzheimer's disease pathogenesis and cognitive impairment.
Alzheimers Res Ther Volume: 16 Page(s): 271
12/21/2024 Authors: Wang Q; Yuan S; Wang C; Huang D; Zhang M; Zhan Y; Gao F; Shi J; Levey AI; Shen Y -
X-chromosome-wide association study for Alzheimer's disease.
Mol Psychiatry
12/04/2024 Authors: Le Borgne J; Gomez L; Heikkinen S; Amin N; Ahmad S; Choi SH; Bis J; Grenier-Boley B; Rodriguez OG; Kleineidam L -
Basic Science and Pathogenesis.
Alzheimers Dement Volume: 20 Suppl 1 Page(s): e089491
12/01/2024 Authors: Zhao P; Fadel OE; Le A; Mangleburg CG; Wu T; Dhindsa J; Amoh BK; Marella AS; Li Y; Seyfried NT -
Technology literacy and access to digital resources for remote assessment among adults enrolled in Alzheimer's disease research.
J Alzheimers Dis Volume: 102 Page(s): 1286 - 1296
12/01/2024 Authors: Okafor M; Yang Z; Vickers KL; Sanders K; Simama N; Hewitt KC; Lah J; Levey AI; Goldstein FC; Hajjar I -
Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and implicates causal proteins for Alzheimer's disease.
Nat Genet Volume: 56 Page(s): 2672 - 2684
12/01/2024 Authors: Western D; Timsina J; Wang L; Wang C; Yang C; Phillips B; Wang Y; Liu M; Ali M; Beric A -
Large-scale deep proteomic analysis in Alzheimer's disease brain regions across race and ethnicity.
Alzheimers Dement Volume: 20 Page(s): 8878 - 8897
12/01/2024 Authors: Seifar F; Fox EJ; Shantaraman A; Liu Y; Dammer EB; Modeste E; Duong DM; Yin L; Trautwig AN; Guo Q -
Measuring clinically relevant change in apathy symptoms in ADMET and ADMET 2.
Int Psychogeriatr Volume: 36 Page(s): 1232 - 1244
12/01/2024 Authors: Tumati S; Herrmann N; Perin J; Rosenberg PB; Lerner AJ; Mintzer J; Padala PR; Brawman-Mintzer O; van Dyck CH; Porsteinsson AP -
Comparative neurofilament light chain trajectories in CSF and plasma in autosomal dominant Alzheimer's disease.
Nat Commun Volume: 15 Page(s): 9982
11/18/2024 Authors: Hofmann A; Hsler LM; Lambert M; Kaeser SA; Grber-Sultan S; Obermller U; Kuder-Buletta E; la Fougere C; Laske C; Vglein J -
CSF proteomics identifies early changes in autosomal dominant Alzheimer's disease.
Cell Volume: 187 Page(s): 6309 - 6326.e15
10/31/2024 Authors: Shen Y; Timsina J; Heo G; Beric A; Ali M; Wang C; Yang C; Wang Y; Western D; Liu M -
Correction: Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease.
Mol Neurodegener Volume: 19 Page(s): 71
10/11/2024 Authors: Shantaraman A; Dammer EB; Ugochukwu O; Duong DM; Yin L; Carter EK; Gearing M; Chen-Plotkin A; Lee EB; Trojanowski JQ -
Heparin-enriched plasma proteome is significantly altered in Alzheimer's disease.
Mol Neurodegener Volume: 19 Page(s): 67
10/08/2024 Authors: Guo Q; Ping L; Dammer EB; Duong DM; Yin L; Xu K; Shantaraman A; Fox EJ; Golde TE; Johnson ECB -
Author Correction: Serum proteomics reveal APOE-4-dependent and APOE-4-independent protein signatures in Alzheimer's disease.
Nat Aging Volume: 4 Page(s): 1509
10/01/2024 Authors: Frick EA; Emilsson V; Jonmundsson T; Steindorsdottir AE; Johnson ECB; Puerta R; Dammer EB; Shantaraman A; Cano A; Boada M -
Bridging the gap: Multi-omics profiling of brain tissue in Alzheimer's disease and older controls in multi-ethnic populations.
Alzheimers Dement Volume: 20 Page(s): 7174 - 7192
10/01/2024 Authors: Reddy JS; Heath L; Linden AV; Allen M; Lopes KDP; Seifar F; Wang E; Ma Y; Poehlman WL; Quicksall ZS -
CT1812 biomarker signature from a meta-analysis of CSF proteomic findings from two Phase 2 clinical trials in Alzheimer's disease.
Alzheimers Dement Volume: 20 Page(s): 6860 - 6880
10/01/2024 Authors: Lizama BN; Williams C; North HA; Pandey K; Duong D; Di Caro V; Mecca AP; Blennow K; Zetterberg H; Levey AI -
Serum proteomics reveal APOE-4-dependent and APOE-4-independent protein signatures in Alzheimer's disease.
Nat Aging Volume: 4 Page(s): 1446 - 1464
10/01/2024 Authors: Frick EA; Emilsson V; Jonmundsson T; Steindorsdottir AE; Johnson ECB; Puerta R; Dammer EB; Shantaraman A; Cano A; Boada M -
-Secretase activity, clinical features, and biomarkers of autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analysis of the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS).
Lancet Neurol Volume: 23 Page(s): 913 - 924
09/01/2024 Authors: Schultz SA; Liu L; Schultz AP; Fitzpatrick CD; Levin R; Bellier J-P; Shirzadi Z; Joseph-Mathurin N; Chen CD; Benzinger TLS -
Development of a time-resolved fluorescence resonance energy transfer ultra-high throughput screening assay targeting SYK and FCER1G interaction.
SLAS Discov Volume: 29 Page(s): 100177
09/01/2024 Authors: Du Y; Wang D; Katis VL; Zoeller EL; Qui M; Levey AI; Gileadi O; Fu H; Emory-SAGE-SGC TREAT-AD Center -
Generation of a gene-corrected human isogenic iPSC line from an Alzheimer's disease iPSC line carrying the PSEN1 H163R mutation.
Stem Cell Res Volume: 79 Page(s): 103495
09/01/2024 Authors: Hernndez D; Morgan Schlicht S; Elli Clarke J; Daniszewski M; Karch CM; Dominantly Inherited Alzheimer Network (DIAN); Goate AM; Pbay A -
Lower Prevalence of Asymptomatic Alzheimer's Disease Among Healthy African Americans.
Ann Neurol Volume: 96 Page(s): 463 - 475
09/01/2024 Authors: Lah JJ; Tian G; Risk BB; Hanfelt JJ; Wang L; Zhao L; Hales CM; Johnson ECB; Elmor MB; Malakauskas SJ -
An interim exploratory proteomics biomarker analysis of a phase 2 clinical trial to assess the impact of CT1812 in Alzheimer's disease.
Neurobiol Dis Volume: 199 Page(s): 106575
09/01/2024 Authors: Lizama BN; North HA; Pandey K; Williams C; Duong D; Cho E; Di Caro V; Ping L; Blennow K; Zetterberg H -
Integrative proteomics identifies a conserved A amyloid responsome, novel plaque proteins, and pathology modifiers in Alzheimer's disease.
Cell Rep Med Volume: 5 Page(s): 101669
08/20/2024 Authors: Levites Y; Dammer EB; Ran Y; Tsering W; Duong D; Abreha M; Gadhavi J; Lolo K; Trejo-Lopez J; Phillips J -
Antibody characterization is critical to enhance reproducibility in biomedical research.
Elife Volume: 13
08/14/2024 Authors: Kahn RA; Virk H; Laflamme C; Houston DW; Polinski NK; Meijers R; Levey AI; Saper CB; Errington TM; Turn RE -
Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease.
Mol Neurodegener Volume: 19 Page(s): 60
08/06/2024 Authors: Shantaraman A; Dammer EB; Ugochukwu O; Duong DM; Yin L; Carter EK; Gearing M; Chen-Plotkin A; Lee EB; Trojanowski JQ -
Proteomic analysis of Alzheimer's disease cerebrospinal fluid reveals alterations associated with APOE 4 and atomoxetine treatment.
Sci Transl Med Volume: 16 Page(s): eadn3504
06/26/2024 Authors: Dammer EB; Shantaraman A; Ping L; Duong DM; Gerasimov ES; Ravindran SP; Gudmundsdottir V; Frick EA; Gomez GT; Walker KA -
Development of a Time-Resolved Fluorescence Resonance Energy Transfer ultra-high throughput screening assay for targeting SYK and FCER1G interaction.
06/13/2024 Authors: Du Y; Wang D; Katis VL; Zoeller EL; Qui M; Levey AI; Gileadi O; Emory-SAGE-SGC TREAT-AD Center; Fu H -
Adverse effects of methylphenidate for apathy in patients with Alzheimer's disease (ADMET2 trial).
Int J Geriatr Psychiatry Volume: 39 Page(s): e6108
04/27/2018 Authors: Zeng L; Perin J; Gross AL; Shade D; Lanctt KL; Lerner AJ; Mintzer JE; Brawman-Mintzer O; Padala PR; van Dyck CH -
Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid.
Alzheimers Dement Volume: 20 Page(s): 4043 - 4065
06/01/2024 Authors: Wojtas AM; Dammer EB; Guo Q; Ping L; Shantaraman A; Duong DM; Yin L; Fox EJ; Seifar F; Lee EB -
Brain cholesterol and Alzheimer's disease: challenges and opportunities in probe and drug development.
Brain Volume: 147 Page(s): 1622 - 1635
05/03/2024 Authors: Ahmed H; Wang Y; Griffiths WJ; Levey AI; Pikuleva I; Liang SH; Haider A -
Deconstructing pathological tau by biological process in early stages of Alzheimer disease: a method for quantifying tau spatial spread in neuroimaging.
EBioMedicine Volume: 103 Page(s): 105080
05/01/2024 Authors: Doering S; McCullough A; Gordon BA; Chen CD; McKay N; Hobbs D; Keefe S; Flores S; Scott J; Smith H -
The association between neighborhood deprivation and DNA methylation in an autopsy cohort.
Aging (Albany NY) Volume: 16 Page(s): 6694 - 6716
04/24/2024 Authors: Pett L; Li Z; Abrishamcar S; Hodge K; Everson T; Christensen G; Gearing M; Kobor MS; Konwar C; MacIsaac JL -
Association between Fine Particulate Matter Exposure and Cerebrospinal Fluid Biomarkers of Alzheimer's Disease among a Cognitively Healthy Population-Based Cohort.
Environ Health Perspect Volume: 132 Page(s): 47001
04/01/2024 Authors: Casey E; Li Z; Liang D; Ebelt S; Levey AI; Lah JJ; Wingo TS; Hls A -
Differential DNA methylation in the brain as potential mediator of the association between traffic-related PM2.5 and neuropathology markers of Alzheimer's disease.
Alzheimers Dement Volume: 20 Page(s): 2538 - 2551
04/01/2024 Authors: Li Z; Liang D; Ebelt S; Gearing M; Kobor MS; Konwar C; Maclsaac JL; Dever K; Wingo AP; Levey AI -
Disentangling Visual Exploration Differences in Cognitive Impairment.
IEEE Trans Biomed Eng Volume: 71 Page(s): 1197 - 1208
04/01/2024 Authors: Jiang Z; Seyedi S; Vickers KL; Manzanares CM; Lah JJ; Levey AI; Clifford GD -
Association of PM2.5 Exposure and Alzheimer Disease Pathology in Brain Bank Donors-Effect Modification by APOE Genotype.
Neurology Volume: 102 Page(s): e209162
03/12/2024 Authors: Christensen GM; Li Z; Liang D; Ebelt S; Gearing M; Levey AI; Lah JJ; Wingo A; Wingo T; Hls A -
Relationships of Cognitive Measures with Cerebrospinal Fluid but Not Imaging Biomarkers of Alzheimer Disease Vary between Black and White Individuals.
Ann Neurol Volume: 95 Page(s): 495 - 506
03/01/2024 Authors: Bonomi S; Lu R; Schindler SE; Bui Q; Lah JJ; Wolk D; Gleason CE; Sperling R; Roberson ED; Levey AI -
Using a standalone ear-EEG device for focal-onset seizure detection.
Bioelectron Med Volume: 10 Page(s): 4
02/07/2024 Authors: Joyner M; Hsu S-H; Martin S; Dwyer J; Chen DF; Sameni R; Waters SH; Borodin K; Clifford GD; Levey AI -
Cryptic exon inclusion is a molecular signature ofLATE-NCin aging brains.
Acta Neuropathol Volume: 147 Page(s): 29
02/03/2024 Authors: Chung M; Carter EK; Veire AM; Dammer EB; Chang J; Duong DM; Raj N; Bassell GJ; Glass JD; Gendron TF -
Systematic proteomics in Autosomal dominant Alzheimer's disease reveals decades-early changes of CSF proteins in neuronal death, and immune pathways.
medRxiv
01/13/2024 Authors: Shen Y; Ali M; Timsina J; Wang C; Do A; Western D; Liu M; Gorijala P; Budde J; Liu H -
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease.
01/09/2024 Authors: Gudmundsdottir V; Frick E; Emilsson V; Jonmundsson T; Steindorsdottir A; Johnson ECB; Puerta R; Dammer E; Shantaraman A; Cano A -
Proteome-wide Analyses Identified Cortical Proteins Associated With Resilience for Varied Cognitive Abilities.
Neurology Volume: 102 Page(s): e207816
01/09/2024 Authors: Zammit AR; Klein H-U; Yu L; Levey AI; Seyfried NT; Wingo AP; Wingo TS; Schneider JA; Bennett DA; Buchman AS -
Genetic and multi-omic risk assessment of Alzheimer's disease implicates core associated biological domains.
Alzheimers Dement (N Y) Volume: 10 Page(s): e12461
01/01/2024 Authors: Cary GA; Wiley JC; Gockley J; Keegan S; Amirtha Ganesh SS; Heath L; Butler RR; Mangravite LM; Logsdon BA; Longo FM -
Sensitivity of the African neuropsychology battery memory subtests and learning slopes in discriminating APOE 4 and amyloid pathology in adult individuals in the Democratic Republic of Congo.
Front Neurol Volume: 15 Page(s): 1320727
01/01/2024 Authors: Ikanga J; Patrick SD; Schwinne M; Patel SS; Epenge E; Gikelekele G; Tshengele N; Kavugho I; Mampunza S; Yarasheski KE -
The Association of Alzheimer's Disease-Related Blood-Based Biomarkers with Cognitive Screening Test Performance in the Congolese Population in Kinshasa.
J Alzheimers Dis Volume: 97 Page(s): 1353 - 1363
01/01/2024 Authors: Schwinne M; Alonso A; Roberts BR; Hickle S; Verberk IMW; Epenge E; Gikelekele G; Tsengele N; Kavugho I; Mampunza S -
Indoor Group Identification and Localization Using Privacy-Preserving Edge Computing Distributed Camera Network.
IEEE J Indoor Seamless Position Navig Volume: 2 Page(s): 51 - 60
01/01/2024 Authors: Hegde C; Kiarashi Y; Rodriguez AD; Levey AI; Doiron M; Kwon H; Clifford GD -
Immunotherapies for Alzheimer's disease.
Science Volume: 382 Page(s): 1242 - 1244
12/15/2023 Authors: Golde TE; Levey AI -
A Amyloid Scaffolds the Accumulation of Matrisome and Additional Proteins in Alzheimer's Disease.
bioRxiv
12/07/2023 Authors: Levites Y; Dammer EB; Ran Y; Tsering W; Duong D; Abreha M; Gadhavi J; Lolo K; Trejo-Lopez J; Phillips JL -
Heterogeneity of Response to Methylphenidate in Apathetic Patients in the ADMET 2 Trial.
Am J Geriatr Psychiatry Volume: 31 Page(s): 1077 - 1087
12/01/2023 Authors: Lanctt KL; Rivet L; Tumati S; Perin J; Sankhe K; Vieira D; Mintzer J; Rosenberg PB; Shade D; Lerner AJ -
Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease.
JAMA Neurol Volume: 80 Page(s): 1353 - 1363
12/01/2023 Authors: Shirzadi Z; Schultz SA; Yau W-YW; Joseph-Mathurin N; Fitzpatrick CD; Levin R; Kantarci K; Preboske GM; Jack CR; Farlow MR -
Discovery of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic approach for Alzheimer's disease.
J Biol Chem Volume: 299 Page(s): 105382
12/01/2023 Authors: Du Y; Bradshaw WJ; Leisner TM; Annor-Gyamfi JK; Qian K; Bashore FM; Sikdar A; Nwogbo FO; Ivanov AA; Frye SV -
Graph Trilateration for Indoor Localization in Sparsely Distributed Edge Computing Devices in Complex Environments Using Bluetooth Technology.
Sensors (Basel) Volume: 23
11/30/2023 Authors: Kiarashi Y; Saghafi S; Das B; Hegde C; Madala VSK; Nakum A; Singh R; Tweedy R; Doiron M; Rodriguez AD -
Serum proteomics reveals APOE dependent and independent protein signatures in Alzheimer's disease.
medRxiv
11/09/2023 Authors: Frick EA; Emilsson V; Jonmundsson T; Steindorsdottir AE; Johnson ECB; Puerta R; Dammer EB; Shantaraman A; Cano A; Boada M -
Cost consequence analysis of Apathy in Dementia Methylphenidate Trial 2 (ADMET 2).
Int Psychogeriatr Volume: 35 Page(s): 664 - 672
11/01/2023 Authors: Lanctt KL; Chen C; Mah E; Kiss A; Li A; Shade D; Scherer RW; Vieira D; Coulibaly H; Rosenberg PB -
Circular-SWAT for deep learning based diagnostic classification of Alzheimer's disease: application to metabolome data.
EBioMedicine Volume: 97 Page(s): 104820
11/01/2023 Authors: Jo T; Kim J; Bice P; Huynh K; Wang T; Arnold M; Meikle PJ; Giles C; Kaddurah-Daouk R; Saykin AJ -
Proteomic Network Analysis of Alzheimer's Disease Cerebrospinal Fluid Reveals Alterations Associated with APOE 4 Genotype and Atomoxetine Treatment.
medRxiv
10/30/2023 Authors: Dammer EB; Shantaraman A; Ping L; Duong DM; Gerasimov ES; Ravindran SP; Gudmundsdottir V; Frick EA; Gomez GT; Walker KA -
In vivo cortical diffusion imaging relates to Alzheimer's disease neuropathology.
Alzheimers Res Ther Volume: 15 Page(s): 165
10/04/2023 Authors: Torso M; Ridgway GR; Valotti M; Hardingham I; Chance SA; National Alzheimers Coordinating Center; Alzheimers Disease Neuroimaging Initiative -
Unbiased classification of the elderly human brain proteome resolves distinct clinical and pathophysiological subtypes of cognitive impairment.
Neurobiol Dis Volume: 186 Page(s): 106286
10/01/2023 Authors: Higginbotham L; Carter EK; Dammer EB; Haque RU; Johnson ECB; Duong DM; Yin L; De Jager PL; Bennett DA; Felsky D -
A protein panel in cerebrospinal fluid for diagnostic and predictive assessment of Alzheimer's disease.
Sci Transl Med Volume: 15 Page(s): eadg4122
09/06/2023 Authors: Haque R; Watson CM; Liu J; Carter EK; Duong DM; Lah JJ; Wingo AP; Roberts BR; Johnson ECB; Saykin AJ -
Sex differences in brain protein expression and disease.
Nat Med Volume: 29 Page(s): 2224 - 2232
09/01/2023 Authors: Wingo AP; Liu Y; Gerasimov ES; Vattathil SM; Liu J; Cutler DJ; Epstein MP; Blokland GAM; Thambisetty M; Troncoso JC -
Integration of plasma and CSF metabolomics with CSF proteomic reveals novel associations between lipid mediators and central nervous system vascular and energy metabolism.
Sci Rep Volume: 13 Page(s): 13752
08/23/2023 Authors: Borkowski K; Seyfried NT; Arnold M; Lah JJ; Levey AI; Hales CM; Dammer EB; Blach C; Louie G; Kaddurah-Daouk R -
Location of pathogenic variants in PSEN1 impacts progression of cognitive, clinical, and neurodegenerative measures in autosomal-dominant Alzheimer's disease.
Aging Cell Volume: 22 Page(s): e13871
08/01/2023 Authors: Schultz SA; Shirzadi Z; Schultz AP; Liu L; Fitzpatrick CD; McDade E; Barthelemy NR; Renton A; Esposito B; Joseph-Mathurin N -
Author Correction: Predicting Alzheimer's disease progression using multi-modal deep learning approach.
Sci Rep Volume: 13 Page(s): 12466
08/01/2023 Authors: Lee G; Nho K; Kang B; Sohn K-A; Kim D; Alzheimers Disease Neuroimaging Initiative -
Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease.
Nat Med Volume: 29 Page(s): 1979 - 1988
08/01/2023 Authors: Johnson ECB; Bian S; Haque RU; Carter EK; Watson CM; Gordon BA; Ping L; Duong DM; Epstein MP; McDade E -
Prognostic relevance of gait-related cognitive functions for dementia conversion in amnestic mild cognitive impairment.
BMC Geriatr Volume: 23 Page(s): 462
07/31/2023 Authors: Tuena C; Maestri S; Serino S; Pedroli E; Stramba-Badiale M; Riva G; Alzheimers Disease Neuroimaging Initiative -
Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer's disease.
Mol Neurodegener Volume: 18 Page(s): 48
07/19/2023 Authors: Modeste ES; Ping L; Watson CM; Duong DM; Dammer EB; Johnson ECB; Roberts BR; Lah JJ; Levey AI; Seyfried NT -
Promoting Healthy Aging: Public Health as a Leader for Reducing Dementia Risk.
Public Policy Aging Rep Volume: 33 Page(s): 92 - 95
07/15/2023 Authors: Jackson EMJ; O'Brien K; McGuire LC; Baumgart M; Gore J; Brandt K; Levey AI; Lamont H -
Brain network decoupling with increased serum neurofilament and reduced cognitive function in Alzheimer's disease.
Brain Volume: 146 Page(s): 2928 - 2943
07/03/2023 Authors: Wheelock MD; Strain JF; Mansfield P; Tu JC; Tanenbaum A; Preische O; Chhatwal JP; Cash DM; Cruchaga C; Fagan AM -
Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with A-PET, neurodegeneration, and cognition.
Alzheimers Dement Volume: 19 Page(s): 2790 - 2804
07/01/2023 Authors: Chatterjee P; Vermunt L; Gordon BA; Pedrini S; Boonkamp L; Armstrong NJ; Xiong C; Singh AK; Li Y; Sohrabi HR -
Molecules of senescent glial cells differentiate Alzheimer's disease from ageing.
J Neurol Neurosurg Psychiatry Volume: 94 Page(s): 550 - 559
07/01/2023 Authors: Dai L; Gao F; Wang Q; Lv X; Cheng Z; Wu Y; Chai X; Zetterberg H; Blennow K; Levey AI -
Differential DNA Methylation in the Brain as Potential Mediator of the Association between Traffic-related PM2.5 and Neuropathology Markers of Alzheimer's Disease.
medRxiv
06/30/2023 Authors: Li Z; Liang D; Ebelt S; Gearing M; Kobor MS; Konwar C; Maclsaac JL; Dever K; Wingo A; Levey A -
Proteogenomic analysis of human cerebrospinal fluid identifies neurologically relevant regulation and informs causal proteins for Alzheimer's disease.
Res Sq
06/09/2023 Authors: Cruchaga C; Western D; Timsina J; Wang L; Wang C; Yang C; Ali M; Beric A; Gorijala P; Kohlfeld P -
Magnetic resonance evidence of increased iron content in subcortical brain regions in asymptomatic Alzheimer's disease.
Hum Brain Mapp Volume: 44 Page(s): 3072 - 3083
06/01/2023 Authors: Lin Q; Shahid S; Hone-Blanchet A; Huang S; Wu J; Bisht A; Loring D; Goldstein F; Levey A; Crosson B -
Associations between neuropsychiatric symptoms of affective and vegetative domains and brain morphology in aging people with mild cognitive impairment and Alzheimer's disease.
Int J Geriatr Psychiatry Volume: 38 Page(s): e5952
06/01/2023 Authors: Cannizzaro A; Ronat L; El Haffaf LM; Hanganu A; ADNI -
Development of FERM domain protein-protein interaction inhibitors for MSN and CD44 as a potential therapeutic strategy for Alzheimer's disease.
bioRxiv
05/22/2023 Authors: Du Y; Bradshaw WJ; Leisner TM; Annor-Gyamfi JK; Qian K; Bashore FM; Sikdar A; Nwogbo FO; Ivanov AA; Frye SV -
APOE expression and secretion are modulated by mitochondrial dysfunction.
Elife Volume: 12
05/12/2023 Authors: Wynne ME; Ogunbona O; Lane AR; Gokhale A; Zlatic SA; Xu C; Wen Z; Duong DM; Rayaprolu S; Ivanova A -
Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease.
Sci Data Volume: 10 Page(s): 261
05/09/2023 Authors: Watson CM; Dammer EB; Ping L; Duong DM; Modeste E; Carter EK; Johnson ECB; Levey AI; Lah JJ; Roberts BR -
First presentation with neuropsychiatric symptoms in autosomal dominant Alzheimer's disease: the Dominantly Inherited Alzheimer's Network Study.
J Neurol Neurosurg Psychiatry Volume: 94 Page(s): 403 - 405
05/01/2023 Authors: O'Connor A; Rice H; Barnes J; Ryan NS; Liu KY; Allegri RF; Berman S; Ringman JM; Cruchaga C; Farlow MR -
MicroRNA-650 Regulates the Pathogenesis of Alzheimer's Disease Through Targeting Cyclin-Dependent Kinase 5.
Mol Neurobiol Volume: 60 Page(s): 2426 - 2441
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Nat Commun Volume: 12 Page(s): 4862
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A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.
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Correction to: Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease.
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Mol Neurodegener Volume: 15 Page(s): 57
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Longitudinal Measurements of Glucocerebrosidase activity in Parkinson's patients.
Ann Clin Transl Neurol Volume: 7 Page(s): 1816 - 1830
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Kv1.3 Channel Expressing Brain Myeloid Cells are a Unique Pro-Inflammatory Subset of Microglia Which Can Be Modulated by Kv1.3 Blockers in Alzheimer's Pathology
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Deep Proteomic Analysis of Alzheimer Disease Brain Identifies New Protein Co-Expression Modules Associated with Disease That are Not Observed at the RNA Level
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Gamma Sensory Flicker for Patients with Prodromal Alzheimer's Disease: A Phase I Trial
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Sci Adv Volume: 6
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Global quantitative analysis of the human brain proteome and phosphoproteome in Alzheimer's disease.
Sci Data Volume: 7 Page(s): 315
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Longitudinal Measurements of Glucocerebrosidase activity in Parkinson's patients and controls: the PPMI study
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Multiscale causal networks identify VGF as a key regulator of Alzheimer's disease.
Nat Commun Volume: 11 Page(s): 3942
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JAMA Netw Open Volume: 3 Page(s): e2012252
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Publisher Correction: Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain.
Nat Neurosci Volume: 23 Page(s): 1034
08/01/2020 Authors: Wingo AP; Fan W; Duong DM; Gerasimov ES; Dammer EB; Liu Y; Harerimana NV; White B; Thambisetty M; Troncoso JC -
A telescope GWAS analysis strategy, based on SNPs-genes-pathways ensamble and on multivariate algorithms, to characterize late onset Alzheimer's disease.
Sci Rep Volume: 10 Page(s): 12063
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Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models.
Cell Rep Volume: 32 Page(s): 107908
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Shattering barriers toward clinically meaningful MSC therapies.
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Author Correction: Multimodal hippocampal subfield grading for Alzheimer's disease classification.
Sci Rep Volume: 10 Page(s): 10969
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Identification of Conserved Proteomic Networks in Neurodegenerative Dementia.
Cell Rep Volume: 31 Page(s): 107807
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Shared proteomic effects of cerebral atherosclerosis and Alzheimer's disease on the human brain.
Nat Neurosci Volume: 23 Page(s): 696 - 700
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Spread of pathological tau proteins through communicating neurons in human Alzheimer's disease.
Nat Commun Volume: 11 Page(s): 2612
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Flow-cytometric microglial sorting coupled with quantitative proteomics identifies moesin as a highly-abundant microglial protein with relevance to Alzheimer's disease.
Mol Neurodegener Volume: 15 Page(s): 28
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Correction to: A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.
Acta Neuropathol Volume: 139 Page(s): 959 - 962
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Functional Analyses of Genetic Risk Variants of Depression-Related Phenotypes in the Human Brain
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Human Brain Proteome-Wide Association Study of Depression Identified 24 Proteins as Tractable Targets for Further Mechanistic Studies
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Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation.
Nat Med Volume: 26 Page(s): 769 - 780
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Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips.
Nat Biomed Eng Volume: 4 Page(s): 421 - 436
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On-chip recapitulation of clinical bone marrow toxicities and patient-specific pathophysiology.
Nat Biomed Eng Volume: 4 Page(s): 394 - 406
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Nat Biomed Eng Volume: 4 Page(s): 477
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The physician-scientist, 75 years after Vannevar Bush-rethinking the 'bench' and 'bedside' dichotomy.
Nat Med Volume: 26 Page(s): 461 - 462
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Robotic fluidic coupling and interrogation of multiple vascularized organ chips.
Nat Biomed Eng Volume: 4 Page(s): 407 - 420
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Tinnitus affects the relative roles of semantics and prosody in the perception of emotions in spoken language.
Int J Audiol Volume: 59 Page(s): 195 - 207
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Challenges and Opportunities with Causal Discovery Algorithms: Application to Alzheimer's Pathophysiology.
Sci Rep Volume: 10 Page(s): 2975
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Purpose in life is a robust protective factor of reported cognitive decline among late middle-aged adults: The Emory Healthy Aging Study.
J Affect Disord Volume: 263 Page(s): 310 - 317
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Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia.
NPJ Genom Med Volume: 5 Page(s): 6
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Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study.
Nat Commun Volume: 11 Page(s): 667
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Analysis of common and rare VPS13C variants in late-onset Parkinson disease.
Neurol Genet Volume: 6 Page(s): 385
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Licensed Bacille Calmette-Guerin (BCG) vaccine formulations differ markedly in viability and cytokine inducing activity
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FAM222A encodes a protein which accumulates in plaques in Alzheimer's disease.
Nat Commun Volume: 11 Page(s): 411
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Functional brain architecture is associated with the rate of tau accumulation in Alzheimer's disease.
Nat Commun Volume: 11 Page(s): 347
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Microengineered human blood-brain barrier platform for understanding nanoparticle transport mechanisms.
Nat Commun Volume: 11 Page(s): 175
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Brain microRNAs associated with late-life depressive symptoms are also associated with cognitive trajectory and dementia.
NPJ Genom Med Volume: 5 Page(s): 6
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Human Colon-on-a-Chip Enables Continuous InVitro Analysis of Colon Mucus Layer Accumulation and Physiology.
Cell Mol Gastroenterol Hepatol Volume: 9 Page(s): 507 - 526
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Informed Consent in Two Alzheimer's Disease Research Centers: Insights From Research Coordinators.
AJOB Empir Bioeth Volume: 11 Page(s): 114 - 124
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Maximizing Safety in the Conduct of Alzheimer's Disease Fluid Biomarker Research in the Era of COVID-19.
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Targeted mass spectrometry to quantify brain-derived cerebrospinal fluid biomarkers in Alzheimer's disease.
Clin Proteomics Volume: 17 Page(s): 19
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Alzheimer's disease: A clinical perspective and future nonhuman primate research opportunities.
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A Novel Joint Brain Network Analysis Using Longitudinal Alzheimer's Disease Data.
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AAV-mediated gene therapy targeting TRPV4 mechanotransduction for inhibition of pulmonary vascular leakage.
APL Bioeng Volume: 3 Page(s): 046103
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Genome-wide association analysis of hippocampal volume identifies enrichment of neurogenesis-related pathways.
Sci Rep Volume: 9 Page(s): 14498
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Cell models of lipid-rich -synuclein aggregation validate known modifiers of -synuclein biology and identify stearoyl-CoA desaturase.
Proc Natl Acad Sci U S A Volume: 116 Page(s): 20760 - 20769
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Tau-Mediated Disruption of the Spliceosome Triggers Cryptic RNA Splicing and Neurodegeneration in Alzheimer's Disease.
Cell Rep Volume: 29 Page(s): 301 - 316.e10
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Transcriptional regulation of homeostatic and disease-associated-microglial genes by IRF1, LXR, and CEBP.
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Kv1.3-Positive Brain Macrophages are Distinct Pro-Inflammatory Microglia Involved in Glutamatergic Synaptic Pruning in AD
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Quantitative Proteomics of Mouse CSF Identifies Novel Human-Relevant Biomarkers of Alzheimer's Disease Pathology
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A Consensus Alzheimer's Disease Brain Protein Co-Expression Network Identifies Robust Biological Alterations Associated with Early- And Late-Stage Disease
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Multimodal Hippocampal Subfield Grading For Alzheimer's Disease Classification.
Sci Rep Volume: 9 Page(s): 13845
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Nat Genet Volume: 51 Page(s): 1423 - 1424
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Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype.
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Network Analysis of a Membrane-Enriched Brain Proteome across Stages of Alzheimer's Disease.
Proteomes Volume: 7
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Stress-induced phospho-ubiquitin formation causes parkin degradation.
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A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.
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CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease.
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Nat Commun Volume: 10 Page(s): 3310
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Regional Amyloid- Load and White Matter Abnormalities Contribute to Hypometabolism in Alzheimer's Dementia.
Mol Neurobiol Volume: 56 Page(s): 4916 - 4924
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A complex human gut microbiome cultured in an anaerobic intestine-on-a-chip.
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Nat Biomed Eng Volume: 3 Page(s): 583
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Association of Early-Onset Alzheimer Disease With Elevated Low-Density Lipoprotein Cholesterol Levels and Rare Genetic Coding Variants of APOB.
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Staphylococcus epidermidis sensitizes hypoxic-ischemic brain injury in a sex-dependent manner
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Mass Spectrometry-Based Quantification of Tau in Human Cerebrospinal Fluid Using a Complementary Tryptic Peptide Standard.
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Viscoelastic Properties of Human Autopsy Brain Tissues as Biomarkers for Alzheimer's Diseases.
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A Phase I Study to Assess the Safety and Cancer-Homing Ability of Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells in Men with Localized Prostate Cancer.
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The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory.
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Large-scale proteomic analysis of human brain identifies proteins associated with cognitive trajectory in advanced age.
Nat Commun Volume: 10 Page(s): 1619
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SMPD1 mutations, activity, and -synuclein accumulation in Parkinson's disease.
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Proteomic analysis of the poly-ubiquitin profiles in Alzheimer's Disease
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White matter in different regions evolves differently during progression to dementia.
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A blood-based signature of cerebrospinal fluid A1-42 status.
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A Review of Statistical Methods in Imaging Genetics.
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A concise and persistent feature to study brain resting-state network dynamics: Findings from the Alzheimer's Disease Neuroimaging Initiative.
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VisMET: a passive, efficient, and sensitive assessment of visuospatial memory in healthy aging, mild cognitive impairment, and Alzheimer's disease.
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Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics.
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Functional signature of conversion of patients with mild cognitive impairment.
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QuickNAT: A fully convolutional network for quick and accurate segmentation of neuroanatomy.
Neuroimage Volume: 186 Page(s): 713 - 727
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Disease progression timeline estimation for Alzheimer's disease using discriminative event based modeling.
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Accurate risk estimation of -amyloid positivity to identify prodromal Alzheimer's disease: Cross-validation study of practical algorithms.
Alzheimers Dement Volume: 15 Page(s): 194 - 204
02/01/2019 Authors: Palmqvist S; Insel PS; Zetterberg H; Blennow K; Brix B; Stomrud E; Alzheimer's Disease Neuroimaging Initiative; Swedish BioFINDER study; Mattsson N; Hansson O -
Altered bile acid profile in mild cognitive impairment and Alzheimer's disease: Relationship to neuroimaging and CSF biomarkers.
Alzheimers Dement Volume: 15 Page(s): 232 - 244
02/01/2019 Authors: Nho K; Kueider-Paisley A; MahmoudianDehkordi S; Arnold M; Risacher SL; Louie G; Blach C; Baillie R; Han X; Kastenmller G -
A Novel Method to Estimate Long-Term Chronological Changes From Fragmented Observations in Disease Progression.
Clin Pharmacol Ther Volume: 105 Page(s): 436 - 447
02/01/2019 Authors: Ishida T; Tokuda K; Hisaka A; Honma M; Kijima S; Takatoku H; Iwatsubo T; Moritoyo T; Suzuki H; Alzheimer's Disease Neuroimaging Initiative -
MAPT rs242557 variant is associated with hippocampus tau uptake on 18F-AV-1451 PET in non-demented elders.
Aging (Albany NY) Volume: 11 Page(s): 874 - 884
01/31/2019 Authors: Shen X-N; Miao D; Li J-Q; Tan C-C; Cao X-P; Tan L; Yu J-T -
Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.
Nat Med Volume: 25 Page(s): 152 - 164
01/01/2019 Authors: Swarup V; Hinz FI; Rexach JE; Noguchi K-I; Toyoshiba H; Oda A; Hirai K; Sarkar A; Seyfried NT; Cheng C -
Altered bile acid profile associates with cognitive impairment in Alzheimer's disease-An emerging role for gut microbiome.
Alzheimers Dement Volume: 15 Page(s): 76 - 92
01/01/2019 Authors: MahmoudianDehkordi S; Arnold M; Nho K; Ahmad S; Jia W; Xie G; Louie G; Kueider-Paisley A; Moseley MA; Thompson JW -
Understanding disease progression and improving Alzheimer's disease clinical trials: Recent highlights from the Alzheimer's Disease Neuroimaging Initiative.
Alzheimers Dement Volume: 15 Page(s): 106 - 152
01/01/2019 Authors: Veitch DP; Weiner MW; Aisen PS; Beckett LA; Cairns NJ; Green RC; Harvey D; Jack CR; Jagust W; Morris JC -
Next Generation Sequencing Analysis in Early Onset Dementia Patients.
J Alzheimers Dis Volume: 67 Page(s): 243 - 256
01/01/2019 Authors: Bonvicini C; Scassellati C; Benussi L; Di Maria E; Maj C; Ciani M; Fostinelli S; Mega A; Bocchetta M; Lanzi G -
A Homolog for Dementia Case Finding with Replication in the Alzheimer's Disease Neuroimaging Initiative.
J Alzheimers Dis Volume: 67 Page(s): 67 - 79
01/01/2019 Authors: Royall DR; Palmer RF; Alzheimers Disease Neuroimaging Initiative -
Longitudinal Brain Atrophy Rates in Transient Ischemic Attack and Minor Ischemic Stroke Patients and Cognitive Profiles.
Front Neurol Volume: 10 Page(s): 18
01/01/2019 Authors: Munir M; Ursenbach J; Reid M; Gupta Sah R; Wang M; Sitaram A; Aftab A; Tariq S; Zamboni G; Griffanti L -
Diffusion MRI Indices and Their Relation to Cognitive Impairment in Brain Aging: The Updated Multi-protocol Approach in ADNI3.
Front Neuroinform Volume: 13 Page(s): 2
01/01/2019 Authors: Zavaliangos-Petropulu A; Nir TM; Thomopoulos SI; Reid RI; Bernstein MA; Borowski B; Jack CR; Weiner MW; Jahanshad N; Thompson PM -
Random forest prediction of Alzheimer's disease using pairwise selection from time series data.
PLoS One Volume: 14 Page(s): e0211558
01/01/2019 Authors: Moore PJ; Lyons TJ; Gallacher J; Alzheimers Disease Neuroimaging Initiative -
The Relationship Between Hippocampal Volumes and Delayed Recall Is Modified by APOE 4 in Mild Cognitive Impairment.
Front Aging Neurosci Volume: 11 Page(s): 36
01/01/2019 Authors: Wang X; Zhou W; Ye T; Lin X; Zhang J; Alzheimers Disease Neuroimaging Initiative -
Longitudinal Functional Brain Mapping in Supernormals.
Cereb Cortex Volume: 29 Page(s): 242 - 252
01/01/2019 Authors: Wang X; Ren P; Baran TM; Raizada RDS; Mapstone M; Lin F; Alzheimers Disease Neuroimaging Initiative -
Robust Motion Regression of Resting-State Data Using a Convolutional Neural Network Model.
Front Neurosci Volume: 13 Page(s): 169
01/01/2019 Authors: Yang Z; Zhuang X; Sreenivasan K; Mishra V; Cordes D; Alzheimers Disease Neuroimaging Initiative -
Evaluating trajectories of episodic memory in normal cognition and mild cognitive impairment: Results from ADNI.
PLoS One Volume: 14 Page(s): e0212435
01/01/2019 Authors: Ding X; Charnigo RJ; Schmitt FA; Kryscio RJ; Abner EL; Alzheimers Disease Neuroimaging Initiative -
Prognosis of conversion of mild cognitive impairment to Alzheimer's dementia by voxel-wise Cox regression based on FDG PET data.
Neuroimage Clin Volume: 21 Page(s): 101637
01/01/2019 Authors: Srensen A; Blazhenets G; Rcker G; Schiller F; Meyer PT; Frings L; Alzheimer's Disease Neuroimaging Initiative -
Cortical thickness atrophy in the transentorhinal cortex in mild cognitive impairment.
Neuroimage Clin Volume: 21 Page(s): 101617
01/01/2019 Authors: Kulason S; Tward DJ; Brown T; Sicat CS; Liu C-F; Ratnanather JT; Younes L; Bakker A; Gallagher M; Albert M -
Increased yield of full GBA sequencing in Ashkenazi Jews with Parkinson's disease.
Eur J Med Genet Volume: 62 Page(s): 65 - 69
01/01/2019 Authors: Ruskey JA; Greenbaum L; Roncire L; Alam A; Spiegelman D; Liong C; Levy OA; Waters C; Fahn S; Marder KS -
The Feasibility of Measuring Gait in an Outpatient Cognitive Neurology Clinical Setting.
J Alzheimers Dis Volume: 71 Page(s): S51 - S55
01/01/2019 Authors: Nocera JR; Arsik I; Keskinocak P; Lepley-Flood A; Lah JJ; Levey AI; Esper GJ -
Re-examining physician-scientist training through the prism of the discovery-invention cycle.
F1000Res Volume: 8 Page(s): 2123
01/01/2019 Authors: Sarma GP; Levey A; Faundez V -
Frequency of the TREM2 R47H Variant in Various Neurodegenerative Disorders.
Alzheimer Dis Assoc Disord Volume: 33 Page(s): 327 - 330
01/01/2019 Authors: Ayer AH; Wojta K; Ramos EM; Dokuru D; Chen JA; Karydas AM; Papatriantafyllou JD; Agiomyrgiannakis D; Kamtsadeli V; Tsinia N -
Rationale and Design of the Emory Healthy Aging and Emory Healthy Brain Studies.
Neuroepidemiology Volume: 53 Page(s): 187 - 200
01/01/2019 Authors: Goetz ME; Hanfelt JJ; John SE; Bergquist SH; Loring DW; Quyyumi A; Clifford GD; Vaccarino V; Goldstein F; Johnson Nd TM -
LRP10 in -synucleinopathies.
Lancet Neurol Volume: 17 Page(s): 1033 - 1034
12/01/2018 Authors: Pihlstrm L; Schottlaender L; Chelban V; Houlden H; MSA Exome Consortium -
Fast Multi-Task SCCA Learning with Feature Selection for Multi-Modal Brain Imaging Genetics.
Volume: 2018 Page(s): 356 - 361
12/01/2018 Authors: Du L; Liu K; Yao X; Risacher SL; Han J; Guo L; Saykin AJ; Shen L; Alzheimers Disease Neuroimaging Initiative -
Sex-specific genetic predictors of Alzheimer's disease biomarkers.
Acta Neuropathol Volume: 136 Page(s): 857 - 872
12/01/2018 Authors: Deming Y; Dumitrescu L; Barnes LL; Thambisetty M; Kunkle B; Gifford KA; Bush WS; Chibnik LB; Mukherjee S; De Jager PL -
Uncovering the heterogeneity and temporal complexity of neurodegenerative diseases with Subtype and Stage Inference.
Nat Commun Volume: 9 Page(s): 4273
10/15/2018 Authors: Young AL; Marinescu RV; Oxtoby NP; Bocchetta M; Yong K; Firth NC; Cash DM; Thomas DL; Dick KM; Cardoso J -
Deep proteomic network analysis of Alzheimer's disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease.
Mol Neurodegener Volume: 13 Page(s): 52
10/04/2018 Authors: Johnson ECB; Dammer EB; Duong DM; Yin L; Thambisetty M; Troncoso JC; Lah JJ; Levey AI; Seyfried NT -
Establishing a Roadmap for Brain-Based Protein Biomarkers in Alzheimer's Disease
Volume: 84 Page(s): S165 - S166
10/01/2018 Authors: Zhou M; Duong DM; Ping L; Dammer EB; Gearing M; Lah JJ; Levey AI; Seyfried NT -
Deep Proteomic Network Analysis of AD Brain Reveals Alterations in RNA Binding Proteins and RNA Splicing Associated with Disease
Volume: 84 Page(s): S68 - S68
10/01/2018 Authors: Johnson E; Dammer E; Duc D; Thambisetty M; Troncoso J; Lah J; Levey A; Seyfried N -
Quantitative Proteomics of the Human Brain Reveals Proteins Associated with Cognitive Resilience
ANNALS OF NEUROLOGY Volume: 84 Page(s): S62 - S62
10/01/2018 Authors: Wingo AP; Dammer EB; Duc D; Breen M; Logsdon B; Yang J; Beach TG; Reiman E; Thambisetty M; Troncosco J -
The Role of the Inflammation Module Hub Protein Moesin in AD
Volume: 84 Page(s): S160 - S160
10/01/2018 Authors: Betarbet R; Raza SA; Webster J; Eric DB; Duong D; Seyfried NT; Levey AI; Rangaraju S; Lah JJ -
Improving Alzheimer's Disease Care for the Citizens of Georgia: The Georgia Memory Network
Volume: 84 Page(s): S69 - S69
10/01/2018 Authors: Hales C; Dillard R; Sudduth S; Medders L; Loring D; Hepburn K; Johnson T; Humberstone S; Levey A; Lah J -
Proteomic Changes in Frontotemporal Lobar Degeneration Due to Microtubule Associated Protein Tau (MAPT) Mutations
Volume: 84 Page(s): S161 - S161
10/01/2018 Authors: Hales C; Duc D; Seyfried N; Webster J; Levey A; Lah J; Dammer E -
Quantitative Proteomics of CSF and Plasma Reveals Candidate Biomarkers Linked to Immune-Related Pathways in Alzheimer's Disease
Volume: 84 Page(s): S64 - S65
10/01/2018 Authors: Duong DM; Lah JJ; Levey AI; Seyfried NT -
A Passive Assessment of Discrimination Memory during Healthy Aging, Mild Cognitive Impairment, and Alzheimer's Disease
Volume: 84 Page(s): S162 - S163
10/01/2018 Authors: Haque R; Levey A -
Effects of APOE Genotype on Protein Co-Expression in Alzheimer's Disease
Volume: 84 Page(s): S164 - S164
10/01/2018 Authors: Dammer EB; Dai J; Johnson ECB; Duong DM; Gearing M; Lah JJ; Levey AI; Wingo TS; Seyfried NT -
Quantitative Analysis of the Brain Ubiquitylome in Alzheimer's Disease.
Proteomics Volume: 18 Page(s): e1800108
10/01/2018 Authors: Abreha MH; Dammer EB; Ping L; Zhang T; Duong DM; Gearing M; Lah JJ; Levey AI; Seyfried NT -
Comprehensive Mapping of Alzheimer's Disease Brain Ubiquitin Pattern Revealed Novel Tau Ubiquitylation Sites
Volume: 84 Page(s): S65 - S65
10/01/2018 Authors: Abreha M; Dammer E; Ping L; Duc D; Gearing M; Lah J; Levey A; Seyfried N -
A Search for Predictive AD Biomarkers: The Emory Healthy Brain Study
Volume: 84 Page(s): S170 - S170
10/01/2018 Authors: Lah JJ; Goetz ME; John S; Lewis LM; Lomba C; Bergquist SH; Clifford GD; Goldstein FC; Loring DW; Kuerston R -
Brain microRNAs Associated with Cognitive Resilience
Volume: 84 Page(s): S161 - S162
10/01/2018 Authors: Wingo AP; Perumal T; Yang H-S; Schneider JA; Jin P; Lah JJ; Levey A; Bennett DA; De Jager PL; Wingo TS -
Characteristic patterns of inter- and intra-hemispheric metabolic connectivity in patients with stable and progressive mild cognitive impairment and Alzheimer's disease.
Sci Rep Volume: 8 Page(s): 13807
09/14/2018 Authors: Huang S-Y; Hsu J-L; Lin K-J; Liu H-L; Wey S-P; Hsiao I-T; Alzheimers Disease Neuroimaging Initiative -
The Mount Sinai cohort of large-scale genomic, transcriptomic and proteomic data in Alzheimer's disease.
Sci Data Volume: 5 Page(s): 180185
09/11/2018 Authors: Wang M; Beckmann ND; Roussos P; Wang E; Zhou X; Wang Q; Ming C; Neff R; Ma W; Fullard JF -
Medical Image Imputation from Image Collections.
IEEE Trans Med Imaging
08/22/2018 Authors: Dalca AV; Bouman KL; Freeman WT; Rost NS; Sabuncu MR; Golland P -
Association of Low Lysosomal Enzymes Activity With Brain Arterial Dilatation.
Stroke Volume: 49 Page(s): 1977 - 1980
08/01/2018 Authors: Shah H; Liong C; Levy OA; Waters C; Fahn S; Marder K; Kang UJ; Wolf P; Oliva P; Zhang K -
Hippocampal place cell dysfunction and the effects of muscarinic M1 receptor agonism in a rat model of Alzheimer's disease.
Hippocampus Volume: 28 Page(s): 568 - 585
08/01/2018 Authors: Galloway CR; Ravipati K; Singh S; Lebois EP; Cohen RM; Levey AI; Manns JR -
Sex-Specific Association of Apolipoprotein E With Cerebrospinal Fluid Levels of Tau.
JAMA Neurol Volume: 75 Page(s): 989 - 998
08/01/2018 Authors: Hohman TJ; Dumitrescu L; Barnes LL; Thambisetty M; Beecham G; Kunkle B; Gifford KA; Bush WS; Chibnik LB; Mukherjee S -
RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.
J Biol Chem Volume: 293 Page(s): 11047 - 11066
07/13/2018 Authors: Bishof I; Dammer EB; Duong DM; Kundinger SR; Gearing M; Lah JJ; Levey AI; Seyfried NT -
Adeno-Associated Viral Vector (Serotype 2)-Nerve Growth Factor for Patients With Alzheimer Disease: A Randomized Clinical Trial.
JAMA Neurol Volume: 75 Page(s): 834 - 841
07/01/2018 Authors: Rafii MS; Tuszynski MH; Thomas RG; Barba D; Brewer JB; Rissman RA; Siffert J; Aisen PS; AAV2-NGF Study Team -
Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins.
Mol Neurodegener Volume: 13 Page(s): 34
06/28/2018 Authors: Rangaraju S; Dammer EB; Raza SA; Gao T; Xiao H; Betarbet R; Duong DM; Webster JA; Hales CM; Lah JJ -
Analysis of shared heritability in common disorders of the brain.
Science Volume: 360
06/22/2018 Authors: Brainstorm Consortium; Anttila V; Bulik-Sullivan B; Finucane HK; Walters RK; Bras J; Duncan L; Escott-Price V; Falcone GJ; Gormley P -
Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy InVitro.
Cell Rep Volume: 23 Page(s): 3698
06/19/2018 Authors: Hassell BA; Goyal G; Lee E; Sontheimer-Phelps A; Levy O; Chen CS; Ingber DE -
Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer's disease.
Mol Neurodegener Volume: 13 Page(s): 24
05/01/2018 Authors: Rangaraju S; Dammer EB; Raza SA; Rathakrishnan P; Xiao H; Gao T; Duong DM; Pennington MW; Lah JJ; Seyfried NT -
Author Correction: Towards an arthritis flare-responsive drug deliverysystem.
Nat Commun Volume: 9 Page(s): 1954
05/11/2018 Authors: Joshi N; Yan J; Levy S; Bhagchandani S; Slaughter KV; Sherman NE; Amirault J; Wang Y; Riegel L; He X -
Guanabenz promotes neuronal survival via enhancement of ATF4 and parkin expression in models of Parkinson disease.
Exp Neurol Volume: 303 Page(s): 95 - 107
05/01/2018 Authors: Sun X; Aim P; Dai D; Ramalingam N; Crary JF; Burke RE; Greene LA; Levy OA -
Biologically Inspired, iterative engineering of a Human Lymphoid Follicle Chip
Volume: 200
05/01/2018 Authors: Goyal G; Long J; Levy O; Ingber DE -
Alpha Galactosidase A Activity in Parkinson Disease
Volume: 90
04/10/2018 Authors: Alcalay R; Levy O; Waters C; Fahn S; Ford B; Kuo S-H; Vanegas-Arroyave N; Shah H; Liong C; Narayan S -
Multimodal and Multiscale Deep Neural Networks for the Early Diagnosis of Alzheimer's Disease using structural MR and FDG-PET images.
Sci Rep Volume: 8 Page(s): 5697
04/09/2018 Authors: Lu D; Popuri K; Ding GW; Balachandar R; Beg MF; Alzheimers Disease Neuroimaging Initiative -
Towards an arthritis flare-responsive drug delivery system.
Nat Commun Volume: 9 Page(s): 1275
04/03/2018 Authors: Joshi N; Yan J; Levy S; Bhagchandani S; Slaughter KV; Sherman NE; Amirault J; Wang Y; Riegel L; He X -
18F-florbetapir Positron Emission Tomography-determined Cerebral -Amyloid Deposition and Neurocognitive Performance after Cardiac Surgery.
Anesthesiology Volume: 128 Page(s): 728 - 744
04/01/2018 Authors: Klinger RY; James OG; Borges-Neto S; Bisanar T; Li Y-J; Qi W; Berger M; Terrando N; Newman MF; Doraiswamy PM -
Alpha galactosidase A activity in Parkinson's disease.
Neurobiol Dis Volume: 112 Page(s): 85 - 90
04/01/2018 Authors: Alcalay RN; Wolf P; Levy OA; Kang UJ; Waters C; Fahn S; Ford B; Kuo SH; Vanegas N; Shah H -
INTEGRATING SEMI-SUPERVISED LABEL PROPAGATION AND RANDOM FORESTS FOR MULTI-ATLAS BASED HIPPOCAMPUS SEGMENTATION.
Volume: 2018 Page(s): 154 - 157
04/01/2018 Authors: Zheng Q; Fan Y -
Global quantitative analysis of the human brain proteome in Alzheimer's and Parkinson's Disease.
Sci Data Volume: 5 Page(s): 180036
03/13/2018 Authors: Ping L; Duong DM; Yin L; Gearing M; Lah JJ; Levey AI; Seyfried NT -
Brain multiplexes reveal morphological connectional biomarkers fingerprinting late brain dementia states.
Sci Rep Volume: 8 Page(s): 4103
03/07/2018 Authors: Mahjoub I; Mahjoub MA; Rekik I; Alzheimers Disease Neuroimaging Initiative -
Evidence for brain glucose dysregulation in Alzheimer's disease.
Alzheimers Dement Volume: 14 Page(s): 318 - 329
03/01/2018 Authors: An Y; Varma VR; Varma S; Casanova R; Dammer E; Pletnikova O; Chia CW; Egan JM; Ferrucci L; Troncoso J -
Conserved brain myelination networks are altered in Alzheimer's and other neurodegenerative diseases.
Alzheimers Dement Volume: 14 Page(s): 352 - 366
03/01/2018 Authors: Allen M; Wang X; Burgess JD; Watzlawik J; Serie DJ; Younkin CS; Nguyen T; Malphrus KG; Lincoln S; Carrasquillo MM -
Increased Plasma Beta-Secretase 1 May Predict Conversion to Alzheimer's Disease Dementia in Individuals With Mild Cognitive Impairment.
Biol Psychiatry Volume: 83 Page(s): 447 - 455
03/01/2018 Authors: Shen Y; Wang H; Sun Q; Yao H; Keegan AP; Mullan M; Wilson J; Lista S; Leyhe T; Laske C -
Modeling radiation injury-induced cell death and countermeasure drug responses in a human Gut-on-a-Chip.
Cell Death Dis Volume: 9 Page(s): 223
02/14/2018 Authors: Jalili-Firoozinezhad S; Prantil-Baun R; Jiang A; Potla R; Mammoto T; Weaver JC; Ferrante TC; Kim HJ; Cabral JMS; Levy O -
Kv1.3 inhibition as a potential microglia-targeted therapy for Alzheimer's disease: preclinical proof of concept.
Brain Volume: 141 Page(s): 596 - 612
02/01/2018 Authors: Maezawa I; Nguyen HM; Di Lucente J; Jenkins DP; Singh V; Hilt S; Kim K; Rangaraju S; Levey AI; Wulff H -
The Apathy in Dementia Methylphenidate Trial 2 (ADMET 2): study protocol for a randomized controlled trial.
Trials Volume: 19 Page(s): 46
01/18/2018 Authors: Scherer RW; Drye L; Mintzer J; Lanctt K; Rosenberg P; Herrmann N; Padala P; Brawman-Mintzer O; Burke W; Craft S -
Locus Coeruleus Ablation Exacerbates Cognitive Deficits, Neuropathology, and Lethality in P301S Tau Transgenic Mice.
J Neurosci Volume: 38 Page(s): 74 - 92
01/03/2018 Authors: Chalermpalanupap T; Schroeder JP; Rorabaugh JM; Liles LC; Lah JJ; Levey AI; Weinshenker D -
Spasmodic Dysphonia in Hereditary Spastic Paraplegia Type 7.
Mov Disord Clin Pract Volume: 5 Page(s): 221 - 222
01/15/2018 Authors: Hall D; Stong N; Lippa N; Pitman MJ; Pullman SL; Levy OA -
Context-dependent expression of a conditionally-inducible form of active Akt.
PLoS One Volume: 13 Page(s): e0197899
01/01/2018 Authors: Park S; Burke RE; Kareva T; Kholodilov N; Aim P; Franke TF; Levy O; Greene LA -
Differential Phagocytic Properties of CD45low Microglia and CD45high Brain Mononuclear Phagocytes-Activation and Age-Related Effects.
Front Immunol Volume: 9 Page(s): 405
01/01/2018 Authors: Rangaraju S; Raza SA; Li NX; Betarbet R; Dammer EB; Duong D; Lah JJ; Seyfried NT; Levey AI -
A 'Framingham-like' Algorithm for Predicting 4-Year Risk of Progression to Amnestic Mild Cognitive Impairment or Alzheimer's Disease Using Multidomain Information.
J Alzheimers Dis Volume: 63 Page(s): 1383 - 1393
01/01/2018 Authors: Steenland K; Zhao L; John SE; Goldstein FC; Levey A; Alvaro A; Alzheimers Disease Neuroimaging Initiative -
Dual-Model Radiomic Biomarkers Predict Development of Mild Cognitive Impairment Progression to Alzheimer's Disease.
Front Neurosci Volume: 12 Page(s): 1045
01/01/2018 Authors: Zhou H; Jiang J; Lu J; Wang M; Zhang H; Zuo C; Alzheimers Disease Neuroimaging Initiative -
A proteomic network approach across the ALS-FTD disease spectrum resolves clinical phenotypes and genetic vulnerability in human brain.
EMBO Mol Med Volume: 10 Page(s): 48 - 62
01/01/2018 Authors: Umoh ME; Dammer EB; Dai J; Duong DM; Lah JJ; Levey AI; Gearing M; Glass JD; Seyfried NT -
Genetically elevated high-density lipoprotein cholesterol through the cholesteryl ester transfer protein gene does not associate with risk of Alzheimer's disease.
Alzheimers Dement (Amst) Volume: 10 Page(s): 595 - 598
01/01/2018 Authors: Peloso GM; van der Lee SJ; International Genomics of Alzheimer's Project (IGAP); Destefano AL; Seshardi S -
Characterization of Detergent Insoluble Proteome in Chronic Traumatic Encephalopathy.
J Neuropathol Exp Neurol Volume: 77 Page(s): 40 - 49
01/01/2018 Authors: Cherry JD; Zeineddin A; Dammer EB; Webster JA; Duong D; Seyfried NT; Levey AI; Alvarez VE; Huber BR; Stein TD -
Effects of APOE Genotype on Brain Proteomic Network and Cell Type Changes in Alzheimer's Disease.
Front Mol Neurosci Volume: 11 Page(s): 454
01/01/2018 Authors: Dai J; Johnson ECB; Dammer EB; Duong DM; Gearing M; Lah JJ; Levey AI; Wingo TS; Seyfried NT -
Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer's disease.
Mol Neurodegener Volume: 12 Page(s): 82
11/06/2017 Authors: McKenzie AT; Moyon S; Wang M; Katsyv I; Song W-M; Zhou X; Dammer EB; Duong DM; Aaker J; Zhao Y -
Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty.
Sci Rep Volume: 7 Page(s): 14052
10/25/2017 Authors: Du L; Liu K; Yao X; Yan J; Risacher SL; Han J; Guo L; Saykin AJ; Shen L; Alzheimers Disease Neuroimaging Initiative -
Human Organ Chip Models Recapitulate Orthotopic Lung Cancer Growth, Therapeutic Responses, and Tumor Dormancy InVitro.
Cell Rep Volume: 21 Page(s): 508 - 516
10/10/2017 Authors: Hassell BA; Goyal G; Lee E; Sontheimer-Phelps A; Levy O; Chen CS; Ingber DE -
LSD1 protects against hippocampal and cortical neurodegeneration.
Nat Commun Volume: 8 Page(s): 805
10/09/2017 Authors: Christopher MA; Myrick DA; Barwick BG; Engstrom AK; Porter-Stransky KA; Boss JM; Weinshenker D; Levey AI; Katz DJ -
Systems Pharmacology Approach to Identify Novel Kv1.3 Channel Dependent Mechanisms in Microglial Activation
Volume: 82 Page(s): S30 - S30
10/01/2017 Authors: Raza SA; Deng Q; Dammer EB; Duong D; Tansey MG; Lah JJ; Betarbet R; Seyfried NT; Levey AI; Rangaraju S -
Early-Onset Alzheimer's Disease Is Associated with APOB and Higher Plasma Cholesterol Independent of APOE
Volume: 82 Page(s): S53 - S53
10/01/2017 Authors: Wingo TS; Cutler DJ; Wingo AP; Le N-A; Rabinovici GD; Miller BL; Lah JJ; Levey AI -
Targeting Microglial and Macrophage Kv1.3 Potassium Channels as a Therapeutic Strategy in Alzheimer's Disease
Volume: 82 Page(s): S50 - S51
10/01/2017 Authors: Rangaraju S; Raza SA; Lah JJ; Tansey M; Levey AI -
Targeting Microglial and Macrophage Kv1.3 Potassium Channels as a Therapeutic Strategy in Alzheimer's Disease
Volume: 82 Page(s): S212 - S213
10/01/2017 Authors: Rangaraju S; Raza SA; Tansey MG; Lah JJ; Levey AI -
Loss of native -synuclein multimerization by strategically mutating its amphipathic helix causes abnormal vesicle interactions in neuronal cells.
Hum Mol Genet Volume: 26 Page(s): 3466 - 3481
09/01/2017 Authors: Dettmer U; Ramalingam N; von Saucken VE; Kim T-E; Newman AJ; Terry-Kantor E; Nuber S; Ericsson M; Fanning S; Bartels T -
Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
Nat Genet Volume: 49 Page(s): 1373 - 1384
12/15/1986 Authors: Sims R; van der Lee SJ; Naj AC; Bellenguez C; Badarinarayan N; Jakobsdottir J; Kunkle BW; Boland A; Raybould R; Bis JC -
Integrating Next-Generation Genomic Sequencing and Mass Spectrometry To Estimate Allele-Specific Protein Abundance in Human Brain.
J Proteome Res Volume: 16 Page(s): 3336 - 3347
09/01/2017 Authors: Wingo TS; Duong DM; Zhou M; Dammer EB; Wu H; Cutler DJ; Lah JJ; Levey AI; Seyfried NT -
Proton Pump Inhibitors and Risk of Mild Cognitive Impairment and Dementia.
J Am Geriatr Soc Volume: 65 Page(s): 1969 - 1974
09/01/2017 Authors: Goldstein FC; Steenland K; Zhao L; Wharton W; Levey AI; Hajjar I -
Cascaded Multi-view Canonical Correlation (CaMCCo) for Early Diagnosis of Alzheimer's Disease via Fusion of Clinical, Imaging and Omic Features.
Sci Rep Volume: 7 Page(s): 8137
08/15/2017 Authors: Singanamalli A; Wang H; Madabhushi A; Alzheimers Disease Neuroimaging Initiative -
Transethnic genome-wide scan identifies novel Alzheimer's disease loci.
Alzheimers Dement Volume: 13 Page(s): 727 - 738
07/01/2017 Authors: Jun GR; Chung J; Mez J; Barber R; Beecham GW; Bennett DA; Buxbaum JD; Byrd GS; Carrasquillo MM; Crane PK -
A systems pharmacology-based approach to identify novel Kv1.3 channel-dependent mechanisms in microglial activation.
J Neuroinflammation Volume: 14 Page(s): 128
06/26/2017 Authors: Rangaraju S; Raza SA; Pennati A; Deng Q; Dammer EB; Duong D; Pennington MW; Tansey MG; Lah JJ; Betarbet R -
Disease-Modifying Effects of M1 Muscarinic Acetylcholine Receptor Activation in an Alzheimer's Disease Mouse Model.
ACS Chem Neurosci Volume: 8 Page(s): 1177 - 1187
06/21/2017 Authors: Lebois EP; Schroeder JP; Esparza TJ; Bridges TM; Lindsley CW; Conn PJ; Brody DL; Daniels JS; Levey AI -
Elevated GM3 plasma concentration in idiopathic Parkinson's disease: a lipidomics analysis
Volume: 32
06/01/2017 Authors: Alcalay R; Chan R; Liong C; Perotte A; Zhou B; Shorr E; Marder K; Kang U; Waters C; Levy O -
Gait impairment and cognitive changes in a case of thalamic dementia and motor neuron disease
Volume: 32
06/01/2017 Authors: O'Shea S; Levy O; Vonsattel JP; Cortes E; Alarder K; Mitsumoto H; Alcalay R -
Spasmodic Dysphonia in Hereditary Spastic Paraplegia Type 7
Volume: 32
06/01/2017 Authors: Hall D; Stong N; Lippa N; Pitman M; Pullman S; Levy O -
Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease.
JAMA Neurol Volume: 74 Page(s): 557 - 566
05/01/2017 Authors: Mattsson N; Andreasson U; Zetterberg H; Blennow K; Alzheimers Disease Neuroimaging Initiative -
Elevated GM3 Plasma Concentration in Parkinson's Disease: a Lipidomics Analysis
Volume: 88
04/18/2017 Authors: Alcalay R; Chan R; Perotte A; Zhou B; Liong C; Shorr E; Marder K; Kang U; Waters C; Levy O -
Comparison of detergent-insoluble proteome changes in autosomal dominant Alzheimer's disease brain to late onset AD and transgenic rodents
Volume: 88
04/18/2017 Authors: Hales C; Dammer E; Duong D; Gearing M; Cohen R; Wingo T; Lah J; Levey A; Seyfried N -
Association of AHA Cardiovascular Health Metrics With Cognitive Function, Depression, and Anxiety: The Emory Healthy Aging Study
Volume: 135
03/07/2017 Authors: Alonso A; Goldstein FC; Vaccarino V; Levey AI; Lah JJ; Marcus M -
Family History of Cardiovascular Disease is Associated With Cognitive Function: The Emory Healthy Aging Study
Volume: 135
03/07/2017 Authors: Goetz ME; Marcus M; Vaccarino V; Goldstein F; Levey A; Lah J -
A Multi-network Approach Identifies Protein-Specific Co-expression in Asymptomatic and Symptomatic Alzheimer's Disease.
Cell Syst Volume: 4 Page(s): 60 - 72.e4
01/25/2017 Authors: Seyfried NT; Dammer EB; Swarup V; Nandakumar D; Duong DM; Yin L; Deng Q; Nguyen T; Hales CM; Wingo T -
The State of Systems Genetics in 2017.
Cell Syst Volume: 4 Page(s): 7 - 15
01/25/2017 Authors: Baliga NS; Bjrkegren JLM; Boeke JD; Boutros M; Crawford NPS; Dudley AM; Farber CR; Jones A; Levey AI; Lusis AJ -
Longitudinal measurement and hierarchical classification framework for the prediction of Alzheimer's disease.
Sci Rep Volume: 7 Page(s): 39880
01/12/2017 Authors: Huang M; Yang W; Feng Q; Chen W; Alzheimers Disease Neuroimaging Initiative -
Alpha-2 macroglobulin in Alzheimer's disease: a marker of neuronal injury through the RCAN1 pathway.
Mol Psychiatry Volume: 22 Page(s): 13 - 23
01/01/2017 Authors: Varma VR; Varma S; An Y; Hohman TJ; Seddighi S; Casanova R; Beri A; Dammer EB; Seyfried NT; Pletnikova O -
The Relationship Between Cognitive Functioning and the JNC-8 Guidelines for Hypertension in Older Adults.
J Gerontol A Biol Sci Med Sci Volume: 72 Page(s): 121 - 126
01/01/2017 Authors: Goldstein FC; Hajjar IM; Dunn CB; Levey AI; Wharton W -
Elevated GM3 plasma concentration in idiopathic Parkinson's disease: A lipidomic analysis.
PLoS One Volume: 12 Page(s): e0172348
01/01/2017 Authors: Chan RB; Perotte AJ; Zhou B; Liong C; Shorr EJ; Marder KS; Kang UJ; Waters CH; Levy OA; Xu Y -
Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression.
Proteomics Volume: 16 Page(s): 3042 - 3053
12/01/2016 Authors: Hales CM; Dammer EB; Deng Q; Duong DM; Gearing M; Troncoso JC; Thambisetty M; Lah JJ; Shulman JM; Levey AI -
Effects of Selective M1 Muscarinic Receptor Activation on Hippocampal Spatial Representations and Neuronal Oscillations.
ACS Chem Neurosci Volume: 7 Page(s): 1393 - 1405
10/19/2016 Authors: Lebois EP; Trimper JB; Hu C; Levey AI; Manns JR -
NADPH Dehydrogenase Quinone 1 (NQO1) Demonstrates Increased Expression and Pathologic Aggregation in Glial Cells in Chronic Traumatic Encephalopathy
Volume: 80 Page(s): S195 - S195
10/01/2016 Authors: Hales C; Zeineddin A; Webster J; Giuliano J; Duong D; Seyfried N; Dammer E; Mckee A; Levey A; Lah J -
A Genetic Study of a Large Pedigree with Late-Onset Alzheimer's Disease
Volume: 80 Page(s): S159 - S159
10/01/2016 Authors: Wingo TS; Cutler DJ; Lah JJ; Levey AI -
KTKEGV-Motif Mutations in Alpha-Synuclein Cause Neuronal Death and Defects in Neurite Regrowth After Mechanical Injury
Volume: 80 Page(s): S62 - S63
10/01/2016 Authors: Ramalingam N; Dettmer U; Selkoe DJ; Levy OA -
REDLetr: Workflow and tools to support the migration of legacy clinical data capture systems to REDCap.
Int J Med Inform Volume: 93 Page(s): 103 - 110
09/01/2016 Authors: Dunn WD; Cobb J; Levey AI; Gutman DA -
Bioinspired polydimethylsiloxane-based composites with high shear resistance against wet tissue.
J Mech Behav Biomed Mater Volume: 61 Page(s): 87 - 95
08/01/2016 Authors: Fischer SCL; Levy O; Kroner E; Hensel R; Karp JM; Arzt E -
Tetrandrine identified in a small molecule screen to activate mesenchymal stem cells for enhanced immunomodulation.
Sci Rep Volume: 6 Page(s): 30263
07/26/2016 Authors: Yang Z; Concannon J; Ng KS; Seyb K; Mortensen LJ; Ranganath S; Gu F; Levy O; Tong Z; Martyn K -
Attacking prostate cancer with a prodrug-doped cellular Trojan horse
Volume: 76
07/01/2016 Authors: Brennen N; Levy O; Han E; Rosen DM; Musabeyezu J; Safaee H; Ranganath S; Ngai J; Heinelt M; Billett S -
Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis.
Nat Commun Volume: 7 Page(s): 11934
06/21/2016 Authors: Iturria-Medina Y; Sotero RC; Toussaint PJ; Mateos-Prez JM; Evans AC; Alzheimers Disease Neuroimaging Initiative -
5-Hydroxymethylation-associated epigenetic modifiers of Alzheimer's disease modulate Tau-induced neurotoxicity.
Hum Mol Genet Volume: 25 Page(s): 2437 - 2450
06/15/2016 Authors: Bernstein AI; Lin Y; Street RC; Lin L; Dai Q; Yu L; Bao H; Gearing M; Lah JJ; Nelson PT -
Controlled Inhibition of the Mesenchymal Stromal Cell Pro-inflammatory Secretome via Microparticle Engineering.
Stem Cell Reports Volume: 6 Page(s): 926 - 939
06/14/2016 Authors: Ranganath SH; Tong Z; Levy O; Martyn K; Karp JM; Inamdar MS -
Variant ASGR1 Associated with a Reduced Risk of Coronary Artery Disease.
N Engl J Med Volume: 374 Page(s): 2131 - 2141
06/02/2016 Authors: Nioi P; Sigurdsson A; Thorleifsson G; Helgason H; Agustsdottir AB; Norddahl GL; Helgadottir A; Magnusdottir A; Jonasdottir A; Gretarsdottir S -
A prodrug-doped cellular Trojan Horse for the potential treatment of prostate cancer.
Biomaterials Volume: 91 Page(s): 140 - 150
06/01/2016 Authors: Levy O; Brennen WN; Han E; Rosen DM; Musabeyezu J; Safaee H; Ranganath S; Ngai J; Heinelt M; Milton Y -
Variants with large effects on blood lipids and the role of cholesterol and triglycerides in coronary disease.
Nat Genet Volume: 48 Page(s): 634 - 639
06/01/2016 Authors: Helgadottir A; Gretarsdottir S; Thorleifsson G; Hjartarson E; Sigurdsson A; Magnusdottir A; Jonasdottir A; Kristjansson H; Sulem P; Oddsson A -
SMPD1 mutations, acid-sphingomyelinase activity and alpha-synuclein accumulation in Parkinson's disease
Volume: 31 Page(s): S220 - S220
06/01/2016 Authors: Gan-Or Z; Mallett V; Tavassoly O; Dauvilliers Y; Leblond C; Ambalavanan A; Laurent S; Strong S; Spiegelman D; Dionne-Laporte A -
The effect of MAPT haplotype on neocortical Lewy body pathology in Parkinson disease.
J Neural Transm (Vienna) Volume: 123 Page(s): 583 - 588
06/01/2016 Authors: Robakis D; Cortes E; Clark LN; Vonsattel JPG; Virmani T; Alcalay RN; Crary JF; Levy OA -
Assessment of the genetic variance of late-onset Alzheimer's disease.
Neurobiol Aging Volume: 41 Page(s): 200.e13 - 200.e20
05/01/2016 Authors: Ridge PG; Hoyt KB; Boehme K; Mukherjee S; Crane PK; Haines JL; Mayeux R; Farrer LA; Pericak-Vance MA; Schellenberg GD -
Differential Gene Expression in Microglial Polarized States and in Alzheimer's Disease: Novel Insights Provided by Weighted Correlation Network Analysis (WGCNA)
Volume: 86
04/05/2016 Authors: Rangaraju S; Dammer E; Seyfried N; Levey A -
Differential Gene Expression in Microglial Polarized States and in Alzheimers Disease: Novel Insights Provided by Weighted Correlation Network Analysis (WGCNA)
Volume: 86
04/05/2016 Authors: Rangaraju S; Dammer E; Seyfried N; Levey A -
CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease.
Acta Neuropathol Commun Volume: 4 Page(s): 14
02/17/2016 Authors: Hu WT; Watts KD; Tailor P; Nguyen TP; Howell JC; Lee RC; Seyfried NT; Gearing M; Hales CM; Levey AI -
Racial Disparity in Cognitive and Functional Disability in Hypertension and All-Cause Mortality.
Am J Hypertens Volume: 29 Page(s): 185 - 193
02/01/2016 Authors: Hajjar I; Wharton W; Mack WJ; Levey AI; Goldstein FC -
Engineering Stem Cell Organoids.
Cell Stem Cell Volume: 18 Page(s): 25 - 38
01/07/2016 Authors: Yin X; Mead BE; Safaee H; Langer R; Karp JM; Levy O -
Alzheimer's Disease Risk Polymorphisms Regulate Gene Expression in the ZCWPW1 and the CELF1 Loci.
PLoS One Volume: 11 Page(s): e0148717
01/01/2016 Authors: Karch CM; Ezerskiy LA; Bertelsen S; Alzheimers Disease Genetics Consortium (ADGC); Goate AM -
A Meta-Analysis of Alzheimer's Disease Incidence and Prevalence Comparing African-Americans and Caucasians.
J Alzheimers Dis Volume: 50 Page(s): 71 - 76
01/01/2016 Authors: Steenland K; Goldstein FC; Levey A; Wharton W -
A novel Alzheimer disease locus located near the gene encoding tau protein.
Mol Psychiatry Volume: 21 Page(s): 108 - 117
01/01/2016 Authors: Jun G; Ibrahim-Verbaas CA; Vronskaya M; Lambert J-C; Chung J; Naj AC; Kunkle BW; Wang L-S; Bis JC; Bellenguez C -
Does S129 phosphorylation of alpha-synuclein contribute to neuronal cell death or axonal pathology?
Volume: 27
01/01/2016 Authors: Ramalingam N; Walker CA; Kanter E; Hengst U; Sulzer D; Selkoe DJ; Dettmer U; Levy OA -
SCARB2 variants and glucocerebrosidase activity in Parkinson's disease.
NPJ Parkinsons Dis Volume: 2 Page(s): 16004-
01/01/2016 Authors: Alcalay RN; Levy OA; Wolf P; Oliva P; Zhang XK; Waters CH; Fahn S; Kang U; Liong C; Ford B -
Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses.
Alzheimers Dement Volume: 11 Page(s): 1439 - 1451
12/01/2015 Authors: Mukherjee S; Walter S; Kauwe JSK; Saykin AJ; Bennett DA; Larson EB; Crane PK; Glymour MM; Adult Changes in Thought Study Investigators; Religious Orders Study/Memory and Aging Project Investigators -
Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease.
Nat Commun Volume: 6 Page(s): 8762
11/09/2015 Authors: Zhang Z; Song M; Liu X; Su Kang S; Duong DM; Seyfried NT; Cao X; Cheng L; Sun YE; Ping Yu S -
Ontogeny of serum CCL2, CCL4 and Eotaxin concentrations in early life
Volume: 70 Page(s): 404 - 405
09/01/2015 Authors: Leonardi L; Dowling D; Valentini P; Duse M; Bergelson I; Angelone D; Levy O -
Association Between Angiotensin Receptor Blockers and Longitudinal Decline in Tau in Mild Cognitive Impairment.
JAMA Neurol Volume: 72 Page(s): 1069 - 1070
09/01/2015 Authors: Hajjar I; Levey A -
Modulation of Renin-Angiotensin System May Slow Conversion from Mild Cognitive Impairment to Alzheimer's Disease.
J Am Geriatr Soc Volume: 63 Page(s): 1749 - 1756
09/01/2015 Authors: Wharton W; Goldstein FC; Zhao L; Steenland K; Levey AI; Hajjar I -
Inflammation and cognitive functioning in African Americans and Caucasians.
Int J Geriatr Psychiatry Volume: 30 Page(s): 934 - 941
09/01/2015 Authors: Goldstein FC; Zhao L; Steenland K; Levey AI -
Glucocerebrosidase activity in Parkinson's disease with and without GBA mutations.
Brain Volume: 138 Page(s): 2648 - 2658
09/01/2015 Authors: Alcalay RN; Levy OA; Waters CC; Fahn S; Ford B; Kuo S-H; Mazzoni P; Pauciulo MW; Nichols WC; Gan-Or Z -
Trib3 Is Elevated in Parkinson's Disease and Mediates Death in Parkinson's Disease Models.
J Neurosci Volume: 35 Page(s): 10731 - 10749
07/29/2015 Authors: Aim P; Sun X; Zareen N; Rao A; Berman Z; Volpicelli-Daley L; Bernd P; Crary JF; Levy OA; Greene LA -
Cell therapy--showing cells the way home.
Oncotarget Volume: 6 Page(s): 17857 - 17858
07/20/2015 Authors: Heinelt M; Karp JM; Levy O -
Glucocerebrosidase activity in Parkinson's disease with and without GBA mutations
Volume: 30 Page(s): S449 - S450
06/01/2015 Authors: Alcalay RN; Levy OA; Waters C; Fahn S; Ford B; Kuo SH; Mazzoni P; Pauciulo MW; Nichols W; Gan-Or Z -
Genetic markers of Restless Legs Syndrome in Parkinson disease.
Parkinsonism Relat Disord Volume: 21 Page(s): 582 - 585
06/01/2015 Authors: Gan-Or Z; Alcalay RN; Bar-Shira A; Leblond CS; Postuma RB; Ben-Shachar S; Waters C; Johnson A; Levy O; Mirelman A -
Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.
PLoS Med Volume: 12 Page(s): e1001841
06/01/2015 Authors: stergaard SD; Mukherjee S; Sharp SJ; Proitsi P; Lotta LA; Day F; Perry JRB; Boehme KL; Walter S; Kauwe JS -
Ferritin levels in the cerebrospinal fluid predict Alzheimer's disease outcomes and are regulated by APOE.
Nat Commun Volume: 6 Page(s): 6760
05/19/2015 Authors: Ayton S; Faux NG; Bush AI; Alzheimer's Disease Neuroimaging Initiative -
Loss-of-function variants in ABCA7 confer risk of Alzheimer's disease.
Nat Genet Volume: 47 Page(s): 445 - 447
05/01/2015 Authors: Steinberg S; Stefansson H; Jonsson T; Johannsdottir H; Ingason A; Helgason H; Sulem P; Magnusson OT; Gudjonsson SA; Unnsteinsdottir U -
Application of biomaterials to advance induced pluripotent stem cell research and therapy.
EMBO J Volume: 34 Page(s): 987 - 1008
04/15/2015 Authors: Tong Z; Solanki A; Hamilos A; Levy O; Wen K; Yin X; Karp JM -
TREM2 is associated with increased risk for Alzheimer's disease in African Americans.
Mol Neurodegener Volume: 10 Page(s): 19
04/10/2015 Authors: Jin SC; Carrasquillo MM; Benitez BA; Skorupa T; Carrell D; Patel D; Lincoln S; Krishnan S; Kachadoorian M; Reitz C -
Tau phosphosignatures discriminate Alzheimer Disease from other tauopathies
FASEB JOURNAL Volume: 29
04/01/2015 Authors: Seyfried N; Dammer E; Ren R; Gearing M; Duc D; Lah J; Levey A -
A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy.
JAMA Neurol Volume: 72 Page(s): 414 - 422
04/01/2015 Authors: Chen JA; Wang Q; Davis-Turak J; Li Y; Karydas AM; Hsu SC; Sears RL; Chatzopoulou D; Huang AY; Wojta KJ -
A small-molecule screen for enhanced homing of systemically infused cells.
Cell Rep Volume: 10 Page(s): 1261 - 1268
03/03/2015 Authors: Levy O; Mortensen LJ; Boquet G; Tong Z; Perrault C; Benhamou B; Zhang J; Stratton T; Han E; Safaee H -
CSF beta-amyloid 1-42 - what are we measuring in Alzheimer's disease?
Ann Clin Transl Neurol Volume: 2 Page(s): 131 - 139
02/01/2015 Authors: Hu WT; Watts KD; Shaw LM; Howell JC; Trojanowski JQ; Basra S; Glass JD; Lah JJ; Levey AI -
Rarity of the Alzheimer disease-protective APP A673T variant in the United States.
JAMA Neurol Volume: 72 Page(s): 209 - 216
02/01/2015 Authors: Wang L-S; Naj AC; Graham RR; Crane PK; Kunkle BW; Cruchaga C; Murcia JDG; Cannon-Albright L; Baldwin CT; Zetterberg H -
Gender Differences: A Lifetime Analysis of the Economic Burden of Alzheimer's Disease.
Womens Health Issues Volume: 25 Page(s): 436 - 440
01/01/2015 Authors: Yang Z; Levey A -
LSD1 continuously protects the differentiated state of neurons
Volume: 26
01/01/2015 Authors: Katz D; Christopher M; Myrick D; Engstrom A; Moudgal R; Barwick B; Levey A -
Potassium channel Kv1.3 is highly expressed by microglia in human Alzheimer's disease.
J Alzheimers Dis Volume: 44 Page(s): 797 - 808
01/01/2015 Authors: Rangaraju S; Gearing M; Jin L-W; Levey A -
Quantitative phosphoproteomics of Alzheimer's disease reveals cross-talk between kinases and small heat shock proteins.
Proteomics Volume: 15 Page(s): 508 - 519
01/01/2015 Authors: Dammer EB; Lee AK; Duong DM; Gearing M; Lah JJ; Levey AI; Seyfried NT -
Aggregation properties of the small nuclear ribonucleoprotein U1-70K in Alzheimer disease.
J Biol Chem Volume: 289 Page(s): 35296 - 35313
12/19/2014 Authors: Diner I; Hales CM; Bishof I; Rabenold L; Duong DM; Yi H; Laur O; Gearing M; Troncoso J; Thambisetty M -
Simultaneous imaging of locus coeruleus and substantia nigra with a quantitative neuromelanin MRI approach.
Magn Reson Imaging Volume: 32 Page(s): 1301 - 1306
12/01/2014 Authors: Chen X; Huddleston DE; Langley J; Ahn S; Barnum CJ; Factor SA; Levey AI; Hu X -
Integrated approaches for analyzing U1-70K cleavage in Alzheimer's disease.
J Proteome Res Volume: 13 Page(s): 4526 - 4534
11/07/2014 Authors: Bai B; Chen P-C; Hales CM; Wu Z; Pagala V; High AA; Levey AI; Lah JJ; Peng J -
Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study.
JAMA Neurol Volume: 71 Page(s): 1394 - 1404
11/01/2014 Authors: Naj AC; Jun G; Reitz C; Kunkle BW; Perry W; Park YS; Beecham GW; Rajbhandary RA; Hamilton-Nelson KL; Wang L-S -
Cleavage of tau by asparagine endopeptidase mediates the neurofibrillary pathology in Alzheimer's disease.
Nat Med Volume: 20 Page(s): 1254 - 1262
11/01/2014 Authors: Zhang Z; Song M; Liu X; Kang SS; Kwon I-S; Duong DM; Seyfried NT; Hu WT; Liu Z; Wang J-Z -
Mithramycin A Enhances Survival in Cellular Models of Parkinson Disease by Blocking Induction of the Pro-Death Genes DDIT4/RTP801 and Trib3
Volume: 76 Page(s): S42 - S43
10/01/2014 Authors: Levy OA; Aime P; Greene LA -
Small Nuclear Ribonucleoproteins (snRNPs) Aggregate in Chronic Traumatic Encephalopathy Suggesting Shared Mechanism with Alzheimer's Disease
Volume: 76 Page(s): S116 - S116
10/01/2014 Authors: Hales CM; Mckee AC; Levey AI; Lah JJ -
Mesenchymal stem cells (MSC) as cell-based vectors for PSA-activated proaerolysin to sites of prostate cancer
Volume: 74
10/01/2014 Authors: Brennen WN; Levy O; Ranganath S; Schweizer M; Rosen M; Billet S; Bhowmick N; Denmeade S; Karp J; Isaacs J -
Basal forebrain atrophy and cortical amyloid deposition in nondemented elderly subjects.
Alzheimers Dement Volume: 10 Page(s): S344 - S353
10/01/2014 Authors: Grothe MJ; Ewers M; Krause B; Heinsen H; Teipel SJ; Alzheimer's Disease Neuroimaging Initiative -
Parkin loss of function contributes to RTP801 elevation and neurodegeneration in Parkinson's disease.
Cell Death Dis Volume: 5 Page(s): e1364
08/07/2014 Authors: Roman-Aumedes J; Canal M; Martn-Flores N; Sun X; Prez-Fernndez V; Wewering S; Fernndez-Santiago R; Ezquerra M; Pont-Sunyer C; Lafuente A -
Alzheimer disease risk factors.
JAMA Neurol Volume: 71 Page(s): 1051
08/01/2014 Authors: Richardson JR; German D; Levey A -
Elevated serum DDE and risk for Alzheimer disease--reply.
JAMA Neurol Volume: 71 Page(s): 1056
08/01/2014 Authors: Richardson JR; Levey AI; German DC -
Aggregates of small nuclear ribonucleic acids (snRNAs) in Alzheimer's disease.
Brain Pathol Volume: 24 Page(s): 344 - 351
07/01/2014 Authors: Hales CM; Dammer EB; Diner I; Yi H; Seyfried NT; Gearing M; Glass JD; Montine TJ; Levey AI; Lah JJ -
Comparison of Parkinson risk in Ashkenazi Jewish patients with Gaucher disease and GBA heterozygotes.
JAMA Neurol Volume: 71 Page(s): 752 - 757
06/01/2014 Authors: Alcalay RN; Dinur T; Quinn T; Sakanaka K; Levy O; Waters C; Fahn S; Dorovski T; Chung WK; Pauciulo M -
3R Predominant Tauopathy with Globular Glial Inclusions
Volume: 73 Page(s): 624 - 624
06/01/2014 Authors: Neill S; Glass J; Levey A; Parker M; Cooper D; Gearing M -
Association of brain amyloid- with cerebral perfusion and structure in Alzheimer's disease and mild cognitive impairment.
Brain Volume: 137 Page(s): 1550 - 1561
08/01/2014 Authors: Mattsson N; Tosun D; Insel PS; Simonson A; Jack CR; Beckett LA; Donohue M; Jagust W; Schuff N; Weiner MW -
MAPT haplotype and Lewy body pathology in patients with neurodegenerative disease
Volume: 29 Page(s): S61 - S61
05/01/2014 Authors: Robakis D; Clark LN; Vonsattel JP; Crary JF; Levy O -
U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21.
Mol Neurodegener Volume: 9 Page(s): 15
04/28/2014 Authors: Hales CM; Seyfried NT; Dammer EB; Duong D; Yi H; Gearing M; Troncoso JC; Mufson EJ; Thambisetty M; Levey AI -
Performance-enhanced mesenchymal stem cells via intracellular delivery of steroids.
Sci Rep Volume: 4 Page(s): 4645
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Response to Buslovich and colleagues.
J Am Geriatr Soc Volume: 62 Page(s): 790 - 791
04/01/2014 Authors: Steenland K; Zhao L; Goldstein FC; Levey AI -
TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions.
Acta Neuropathol Volume: 127 Page(s): 407 - 418
03/01/2014 Authors: Gallagher MD; Suh E; Grossman M; Elman L; McCluskey L; Van Swieten JC; Al-Sarraj S; Neumann M; Gelpi E; Ghetti B -
Elevated serum pesticide levels and risk for Alzheimer disease.
JAMA Neurol Volume: 71 Page(s): 284 - 290
03/01/2014 Authors: Richardson JR; Roy A; Shalat SL; von Stein RT; Hossain MM; Buckley B; Gearing M; Levey AI; German DC -
Knowledge of and interest in genetic results among Parkinson disease patients and caregivers.
J Genet Couns Volume: 23 Page(s): 114 - 120
02/01/2014 Authors: Sakanaka K; Waters CH; Levy OA; Louis ED; Chung WK; Marder KS; Alcalay RN -
Two phase 3 trials of bapineuzumab in mild-to-moderate Alzheimer's disease.
N Engl J Med Volume: 370 Page(s): 322 - 333
01/23/2014 Authors: Salloway S; Sperling R; Fox NC; Blennow K; Klunk W; Raskind M; Sabbagh M; Honig LS; Porsteinsson AP; Ferris S -
A cell rolling cytometer reveals the correlation between mesenchymal stem cell dynamic adhesion and differentiation state.
Lab Chip Volume: 14 Page(s): 161 - 166
01/07/2014 Authors: Choi S; Levy O; Coelho MB; Cabral JMS; Karp JM; Karnik R -
Proteomics of protein post-translational modifications implicated in neurodegeneration.
Transl Neurodegener Volume: 3 Page(s): 23
01/01/2014 Authors: Ren R-J; Dammer EB; Wang G; Seyfried NT; Levey AI -
Increased plasma TACE activity in subjects with mild cognitive impairment and patients with Alzheimer's disease.
J Alzheimers Dis Volume: 41 Page(s): 877 - 886
01/01/2014 Authors: Sun Q; Hampel H; Blennow K; Lista S; Levey A; Tang B; Li R; Shen Y -
An assessment by the Statin Cognitive Safety Task Force: 2014 update.
J Clin Lipidol Volume: 8 Page(s): S5 - 16
11/01/2014 Authors: Rojas-Fernandez CH; Goldstein LB; Levey AI; Taylor BA; Bittner V; The National Lipid Association's Safety Task Force -
Pharmacologic inhibition of ROCK2 suppresses amyloid- production in an Alzheimer's disease mouse model.
J Neurosci Volume: 33 Page(s): 19086 - 19098
12/04/2013 Authors: Herskowitz JH; Feng Y; Mattheyses AL; Hales CM; Higginbotham LA; Duong DM; Montine TJ; Troncoso JC; Thambisetty M; Seyfried NT -
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Nat Genet Volume: 45 Page(s): 1452 - 1458
12/01/2013 Authors: Lambert JC; Ibrahim-Verbaas CA; Harold D; Naj AC; Sims R; Bellenguez C; DeStafano AL; Bis JC; Beecham GW; Grenier-Boley B -
Parkinson disease phenotype in Ashkenazi Jews with and without LRRK2 G2019S mutations.
Mov Disord Volume: 28 Page(s): 1966 - 1971
12/01/2013 Authors: Alcalay RN; Mirelman A; Saunders-Pullman R; Tang M-X; Mejia Santana H; Raymond D; Roos E; Orbe-Reilly M; Gurevich T; Bar Shira A -
Reduced CSF p-Tau181 to Tau ratio is a biomarker for FTLD-TDP.
Neurology Volume: 81 Page(s): 1945 - 1952
11/26/2013 Authors: Hu WT; Watts K; Grossman M; Glass J; Lah JJ; Hales C; Shelnutt M; Van Deerlin V; Trojanowski JQ; Levey AI -
Abnormal gephyrin immunoreactivity associated with Alzheimer disease pathologic changes.
J Neuropathol Exp Neurol Volume: 72 Page(s): 1009 - 1015
11/01/2013 Authors: Hales CM; Rees H; Seyfried NT; Dammer EB; Duong DM; Gearing M; Montine TJ; Troncoso JC; Thambisetty M; Levey AI -
TREM2 and neurodegenerative disease.
N Engl J Med Volume: 369 Page(s): 1565 - 1567
10/17/2013 Authors: Rajagopalan P; Hibar DP; Thompson PM -
Systematic analysis of in vitro cell rolling using a multi-well plate microfluidic system.
J Vis Exp Page(s): e50866
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U1 small nuclear ribonucleoprotein complex and RNA splicing alterations in Alzheimer's disease.
Proc Natl Acad Sci U S A Volume: 110 Page(s): 16562 - 16567
10/08/2013 Authors: Bai B; Hales CM; Chen P-C; Gozal Y; Dammer EB; Fritz JJ; Wang X; Xia Q; Duong DM; Street C -
mRNA-engineered mesenchymal stem cells for targeted delivery of interleukin-10 to sites of inflammation.
Blood Volume: 122 Page(s): e23 - e32
01/01/1981 Authors: Levy O; Zhao W; Mortensen LJ; Leblanc S; Tsang K; Fu M; Phillips JA; Sagar V; Anandakumaran P; Ngai J -
Innate immune ontogeny in early life
Volume: 68 Page(s): 683 - 683
09/01/2013 Authors: Leonardi L; Angelone D; Bergelson I; Dowling D; Duse M; Valentini P; Fontanarosa L; Ninkovic J; Levy O -
Statins and cognitive decline in older adults with normal cognition or mild cognitive impairment.
J Am Geriatr Soc Volume: 61 Page(s): 1449 - 1455
09/01/2013 Authors: Steenland K; Zhao L; Goldstein FC; Levey AI -
Predicting brain activity using a Bayesian spatial model.
Stat Methods Med Res Volume: 22 Page(s): 382 - 397
08/01/2013 Authors: Derado G; Bowman FD; Zhang L; Alzheimer's Disease Neuroimaging Initiative Investigators -
Segmentation of MR images via discriminative dictionary learning and sparse coding: application to hippocampus labeling.
Neuroimage Volume: 76 Page(s): 11 - 23
08/01/2013 Authors: Tong T; Wolz R; Coup P; Hajnal JV; Rueckert D; Alzheimer's Disease Neuroimaging Initiative -
Monetary costs of dementia in the United States.
N Engl J Med Volume: 369 Page(s): 489
08/01/2013 Authors: Yang Z; Lin P-J; Levey A -
Neuron enriched nuclear proteome isolated from human brain.
J Proteome Res Volume: 12 Page(s): 3193 - 3206
07/05/2013 Authors: Dammer EB; Duong DM; Diner I; Gearing M; Feng Y; Lah JJ; Levey AI; Seyfried NT -
Functional activity maps based on significance measures and Independent Component Analysis.
Comput Methods Programs Biomed Volume: 111 Page(s): 255 - 268
07/01/2013 Authors: Martnez-Murcia FJ; Grriz JM; Ramrez J; Puntonet CG; Illn IA; Alzheimer's Disease Neuroimaging Initiative -
Semi-supervised multimodal relevance vector regression improves cognitive performance estimation from imaging and biological biomarkers.
Neuroinformatics Volume: 11 Page(s): 339 - 353
07/01/2013 Authors: Cheng B; Zhang D; Chen S; Kaufer DI; Shen D; Alzheimers Disease Neuroimaging Initiative -
NF-B activity is inversely correlated to RNF11 expression in Parkinson's disease.
Neurosci Lett Volume: 547 Page(s): 16 - 20
06/28/2013 Authors: Pranski E; Van Sanford CD; Dalal N; Orr AL; Karmali D; Cooper DS; Gearing M; Lah JJ; Levey AI; Betarbet R -
RING finger protein 11 (RNF11) modulates susceptibility to 6-OHDA-induced nigral degeneration and behavioral deficits through NF-B signaling in dopaminergic cells.
Neurobiol Dis Volume: 54 Page(s): 264 - 279
06/01/2013 Authors: Pranski EL; Dalal NV; Sanford CV; Herskowitz JH; Gearing M; Lazo C; Miller GW; Lah JJ; Levey AI; Betarbet RS -
Novel CSF biomarkers for frontotemporal lobar degeneration with lesions immunoreactive to TDP-43 (FTLD-TDP)
Volume: 80 Page(s): E201 - E201
05/01/2013 Authors: Hu W; Watts K; Grossman M; Glass J; Lah J; Trojanowski J; Levey A -
Standardization of analysis sets for reporting results from ADNI MRI data.
Alzheimers Dement Volume: 9 Page(s): 332 - 337
05/01/2013 Authors: Wyman BT; Harvey DJ; Crawford K; Bernstein MA; Carmichael O; Cole PE; Crane PK; DeCarli C; Fox NC; Gunter JL -
Proteomic analysis of postsynaptic density in Alzheimer's disease.
Clin Chim Acta Volume: 420 Page(s): 62 - 68
05/01/2013 Authors: Zhou J; Jones DR; Duong DM; Levey AI; Lah JJ; Peng J -
GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease.
Neuron Volume: 78 Page(s): 256 - 268
04/24/2013 Authors: Cruchaga C; Kauwe JSK; Harari O; Jin SC; Cai Y; Karch CM; Benitez BA; Jeng AT; Skorupa T; Carrell D -
Generative FDG-PET and MRI model of aging and disease progression in Alzheimer's disease.
PLoS Comput Biol Volume: 9 Page(s): e1002987
04/01/2013 Authors: Dukart J; Kherif F; Mueller K; Adaszewski S; Schroeter ML; Frackowiak RSJ; Draganski B; Alzheimer's Disease Neuroimaging Initiative -
Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity.
Proc Natl Acad Sci U S A Volume: 110 Page(s): 4768 - 4773
03/19/2013 Authors: Jahanshad N; Rajagopalan P; Hua X; Hibar DP; Nir TM; Toga AW; Jack CR; Saykin AJ; Green RC; Weiner MW -
A behavioral task predicts conversion to mild cognitive impairment and Alzheimer's disease.
Am J Alzheimers Dis Other Demen Volume: 28 Page(s): 179 - 184
03/01/2013 Authors: Zola SM; Manzanares CM; Clopton P; Lah JJ; Levey AI -
Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci.
Ann Hum Genet Volume: 77 Page(s): 85 - 105
03/01/2013 Authors: Holton P; Ryten M; Nalls M; Trabzuni D; Weale ME; Hernandez D; Crehan H; Gibbs JR; Mayeux R; Haines JL -
ATF4 protects against neuronal death in cellular Parkinson's disease models by maintaining levels of parkin.
J Neurosci Volume: 33 Page(s): 2398 - 2407
02/06/2013 Authors: Sun X; Liu J; Crary JF; Malagelada C; Sulzer D; Greene LA; Levy OA -
Prediction of Alzheimer's disease in subjects with mild cognitive impairment from the ADNI cohort using patterns of cortical thinning.
Neuroimage Volume: 65 Page(s): 511 - 521
01/15/2013 Authors: Eskildsen SF; Coup P; Garca-Lorenzo D; Fonov V; Pruessner JC; Collins DL; Alzheimer's Disease Neuroimaging Initiative -
Random forest-based similarity measures for multi-modal classification of Alzheimer's disease.
Neuroimage Volume: 65 Page(s): 167 - 175
01/15/2013 Authors: Gray KR; Aljabar P; Heckemann RA; Hammers A; Rueckert D; Alzheimer's Disease Neuroimaging Initiative -
Variant of TREM2 associated with the risk of Alzheimer's disease.
N Engl J Med Volume: 368 Page(s): 107 - 116
01/10/2013 Authors: Jonsson T; Stefansson H; Steinberg S; Jonsdottir I; Jonsson PV; Snaedal J; Bjornsson S; Huttenlocher J; Levey AI; Lah JJ -
Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease.
Alzheimers Res Ther Volume: 5 Page(s): 21
01/01/2013 Authors: Chalermpalanupap T; Kinkead B; Hu WT; Kummer MP; Hammerschmidt T; Heneka MT; Weinshenker D; Levey AI -
Behavior matters--cognitive predictors of survival in amyotrophic lateral sclerosis.
PLoS One Volume: 8 Page(s): e57584
01/01/2013 Authors: Hu WT; Shelnutt M; Wilson A; Yarab N; Kelly C; Grossman M; Libon DJ; Khan J; Lah JJ; Levey AI -
Exploring the potential of the platelet membrane proteome as a source of peripheral biomarkers for Alzheimer's disease.
Alzheimers Res Ther Volume: 5 Page(s): 32
01/01/2013 Authors: Donovan LE; Dammer EB; Duong DM; Hanfelt JJ; Levey AI; Seyfried NT; Lah JJ -
Predicting the location of human perirhinal cortex, Brodmann's area 35, from MRI.
Neuroimage Volume: 64 Page(s): 32 - 42
01/01/2013 Authors: Augustinack JC; Huber KE; Stevens AA; Roy M; Frosch MP; van der Kouwe AJW; Wald LL; Van Leemput K; McKee AC; Fischl B -
Predicting AD conversion: comparison between prodromal AD guidelines and computer assisted PredictAD tool.
PLoS One Volume: 8 Page(s): e55246
01/01/2013 Authors: Liu Y; Mattila J; Ruiz MM; Paajanen T; Koikkalainen J; van Gils M; Herukka S-K; Waldemar G; Ltjnen J; Soininen H -
Mapping the genetic variation of regional brain volumes as explained by all common SNPs from the ADNI study.
PLoS One Volume: 8 Page(s): e71723
05/01/2013 Authors: Bryant C; Giovanello KS; Ibrahim JG; Chang J; Shen D; Peterson BS; Zhu H; Alzheimer's Disease Neuroimaging Initiative -
Effects of baseline CSF -synuclein on regional brain atrophy rates in healthy elders, mild cognitive impairment and Alzheimer's disease.
PLoS One Volume: 8 Page(s): e85443
01/01/2013 Authors: Mattsson N; Insel P; Tosun D; Zhang J; Jack CR; Galasko D; Weiner M; Alzheimers Disease Neuroimaging Initiative -
aBEAT: a toolbox for consistent analysis of longitudinal adult brain MRI.
PLoS One Volume: 8 Page(s): e60344
01/01/2013 Authors: Dai Y; Wang Y; Wang L; Wu G; Shi F; Shen D; Alzheimers Disease Neuroimaging Initiative -
The receiver operational characteristic for binary classification with multiple indices and its application to the neuroimaging study of Alzheimer's disease.
IEEE/ACM Trans Comput Biol Bioinform Volume: 10 Page(s): 173 - 180
01/01/2013 Authors: Wu X; Li J; Ayutyanont N; Protas H; Jagust W; Fleisher A; Reiman E; Yao L; Chen K; Alzheimer's Disease Neuroimaging Initiative -
Man versus machine: comparison of radiologists' interpretations and NeuroQuant volumetric analyses of brain MRIs in patients with traumatic brain injury.
J Neuropsychiatry Clin Neurosci Volume: 25 Page(s): 32 - 39
01/01/2013 Authors: Ross DE; Ochs AL; Seabaugh JM; Shrader CR; Alzheimer's Disease Neuroimaging Initiative -
Clinical Tissue Proteomics Identifies the U1 Small Nuclear Ribonucleoprotein Complex in Alzheimer Disease Pathology
MOLECULAR BIOLOGY OF THE CELL Volume: 24
01/01/2013 Authors: Chen P-C; Bai B; Hales C; Gozal YM; Li Y; Dammer EB; Cantero G; Seyfried NT; Sun YE; Mufson EJ -
High blood pressure and cognitive decline in mild cognitive impairment.
J Am Geriatr Soc Volume: 61 Page(s): 67 - 73
01/01/2013 Authors: Goldstein FC; Levey AI; Steenland NK -
Quantification of Mesenchymal Stem Cell (MSC) delivery to a target site using in vivo confocal microscopy.
PLoS One Volume: 8 Page(s): e78145
01/01/2013 Authors: Mortensen LJ; Levy O; Phillips JP; Stratton T; Triana B; Ruiz JP; Gu F; Karp JM; Lin CP -
Postural and Intention Tremors: A Detailed Clinical Study of Essential Tremor vs. Parkinson's Disease.
Front Neurol Volume: 4 Page(s): 51
01/01/2013 Authors: Sternberg EJ; Alcalay RN; Levy OA; Louis ED -
Confirmatory factor analysis of the ADNI Neuropsychological Battery.
Brain Imaging Behav Volume: 6 Page(s): 528 - 539
12/01/2012 Authors: Park LQ; Gross AL; McLaren DG; Pa J; Johnson JK; Mitchell M; Manly JJ; Alzheimers Disease Neuroimaging Initiative -
Longitudinal change in neuropsychological performance using latent growth models: a study of mild cognitive impairment.
Brain Imaging Behav Volume: 6 Page(s): 540 - 550
12/01/2012 Authors: Johnson JK; Gross AL; Pa J; McLaren DG; Park LQ; Manly JJ; Alzheimers Disease Neuroimaging Initiative -
Cortical signatures of cognition and their relationship to Alzheimer's disease.
Brain Imaging Behav Volume: 6 Page(s): 584 - 598
12/01/2012 Authors: Gross AL; Manly JJ; Pa J; Johnson JK; Park LQ; Mitchell MB; Melrose RJ; Inouye SK; McLaren DG; Alzheimers Disease Neuroimaging Initiative -
Voxel and surface-based topography of memory and executive deficits in mild cognitive impairment and Alzheimer's disease.
Brain Imaging Behav Volume: 6 Page(s): 551 - 567
12/01/2012 Authors: Nho K; Risacher SL; Crane PK; DeCarli C; Glymour MM; Habeck C; Kim S; Lee GJ; Mormino E; Mukherjee S -
The Alzheimer's Disease Assessment Scale-Cognitive-Plus (ADAS-Cog-Plus): an expansion of the ADAS-Cog to improve responsiveness in MCI.
Brain Imaging Behav Volume: 6 Page(s): 489 - 501
12/01/2012 Authors: Skinner J; Carvalho JO; Potter GG; Thames A; Zelinski E; Crane PK; Gibbons LE; Alzheimer's Disease Neuroimaging Initiative -
A composite score for executive functioning, validated in Alzheimer's Disease Neuroimaging Initiative (ADNI) participants with baseline mild cognitive impairment.
Brain Imaging Behav Volume: 6 Page(s): 517 - 527
12/01/2012 Authors: Gibbons LE; Carle AC; Mackin RS; Harvey D; Mukherjee S; Insel P; Curtis SM; Mungas D; Crane PK; Alzheimers Disease Neuroimaging Initiative -
Relationship between baseline brain metabolism measured using [F]FDG PET and memory and executive function in prodromal and early Alzheimer's disease.
Brain Imaging Behav Volume: 6 Page(s): 568 - 583
12/01/2012 Authors: Habeck C; Risacher S; Lee GJ; Glymour MM; Mormino E; Mukherjee S; Kim S; Nho K; DeCarli C; Saykin AJ -
Development and assessment of a composite score for memory in the Alzheimer's Disease Neuroimaging Initiative (ADNI).
Brain Imaging Behav Volume: 6 Page(s): 502 - 516
12/01/2012 Authors: Crane PK; Carle A; Gibbons LE; Insel P; Mackin RS; Gross A; Jones RN; Mukherjee S; Curtis SM; Harvey D -
Dysexecutive and amnesic AD subtypes defined by single indicator and modern psychometric approaches: relationships with SNPs in ADNI.
Brain Imaging Behav Volume: 6 Page(s): 649 - 660
12/01/2012 Authors: Mukherjee S; Trittschuh E; Gibbons LE; Mackin RS; Saykin A; Crane PK; Azheimer's Disease Neuroimaging Initiative -
Genome-wide pathway analysis of memory impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) cohort implicates gene candidates, canonical pathways, and networks.
Brain Imaging Behav Volume: 6 Page(s): 634 - 648
12/01/2012 Authors: Ramanan VK; Kim S; Holohan K; Shen L; Nho K; Risacher SL; Foroud TM; Mukherjee S; Crane PK; Aisen PS -
Beta amyloid, tau, neuroimaging, and cognition: sequence modeling of biomarkers for Alzheimer's Disease.
Brain Imaging Behav Volume: 6 Page(s): 610 - 620
12/01/2012 Authors: Han SD; Gruhl J; Beckett L; Dodge HH; Stricker NH; Farias S; Mungas D; Alzheimers Disease Neuroimaging Initiative -
Common genetic variants in the CLDN2 and PRSS1-PRSS2 loci alter risk for alcohol-related and sporadic pancreatitis.
Nat Genet Volume: 44 Page(s): 1349 - 1354
12/01/2012 Authors: Whitcomb DC; LaRusch J; Krasinskas AM; Klei L; Smith JP; Brand RE; Neoptolemos JP; Lerch MM; Tector M; Sandhu BS -
The association between late-life depression, mild cognitive impairment and dementia: is inflammation the missing link?
Expert Rev Neurother Volume: 12 Page(s): 1339 - 1350
11/01/2012 Authors: Hermida AP; McDonald WM; Steenland K; Levey A -
RNF11 modulates microglia activation through NF-B signalling cascade.
Neurosci Lett Volume: 528 Page(s): 174 - 179
10/24/2012 Authors: Dalal NV; Pranski EL; Tansey MG; Lah JJ; Levey AI; Betarbet RS -
Clinical reasoning: a middle-aged man with episodes of gait imbalance and a newly found genetic mutation.
Neurology Volume: 79 Page(s): e135 - e139
10/16/2012 Authors: Yugrakh MS; Levy OA -
Naming impairment in Alzheimer's disease is associated with left anterior temporal lobe atrophy.
Neuroimage Volume: 63 Page(s): 348 - 355
10/15/2012 Authors: Domoto-Reilly K; Sapolsky D; Brickhouse M; Dickerson BC; Alzheimer's Disease Neuroimaging Initiative -
Comprehensive search for Alzheimer disease susceptibility loci in the APOE region.
Arch Neurol Volume: 69 Page(s): 1270 - 1279
10/01/2012 Authors: Jun G; Vardarajan BN; Buros J; Yu C-E; Hawk MV; Dombroski BA; Crane PK; Larson EB; Alzheimer's Disease Genetics Consortium; Mayeux R -
Plasma biomarkers associated with the apolipoprotein E genotype and Alzheimer disease.
Arch Neurol Volume: 69 Page(s): 1310 - 1317
10/01/2012 Authors: Soares HD; Potter WZ; Pickering E; Kuhn M; Immermann FW; Shera DM; Ferm M; Dean RA; Simon AJ; Swenson F -
Association between polychlorinated biphenyls and Parkinson's disease neuropathology.
Neurotoxicology Volume: 33 Page(s): 1298 - 1304
10/01/2012 Authors: Hatcher-Martin JM; Gearing M; Steenland K; Levey AI; Miller GW; Pennell KD -
Vascular burden and Alzheimer disease pathologic progression.
Neurology Volume: 79 Page(s): 1349 - 1355
09/25/2012 Authors: Lo RY; Jagust WJ; Alzheimer's Disease Neuroimaging Initiative -
Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism.
J Am Coll Cardiol Volume: 60 Page(s): 722 - 729
08/21/2012 Authors: Helgadottir A; Gretarsdottir S; Thorleifsson G; Holm H; Patel RS; Gudnason T; Jones GT; van Rij AM; Eapen DJ; Baas AF -
Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease.
Neurobiol Aging Volume: 33 Page(s): 1599 - 1608
08/01/2012 Authors: Ewers M; Schmitz S; Hansson O; Walsh C; Fitzpatrick A; Bennett D; Minthon L; Trojanowski JQ; Shaw LM; Faluyi YO -
Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases.
Hum Mol Genet Volume: 21 Page(s): 3500 - 3512
08/01/2012 Authors: Coppola G; Chinnathambi S; Lee JJ; Dombroski BA; Baker MC; Soto-Ortolaza AI; Lee SE; Klein E; Huang AY; Sears R -
Asparaginyl endopeptidase cleaves TDP-43 in brain.
Proteomics Volume: 12 Page(s): 2455 - 2463
08/01/2012 Authors: Herskowitz JH; Gozal YM; Duong DM; Dammer EB; Gearing M; Ye K; Lah JJ; Peng J; Levey AI; Seyfried NT -
Novel late-onset Alzheimer disease loci variants associate with brain gene expression.
Neurology Volume: 79 Page(s): 221 - 228
07/17/2012 Authors: Allen M; Zou F; Chai HS; Younkin CS; Crook J; Pankratz VS; Carrasquillo MM; Rowley CN; Nair AA; Middha S -
GGA1-mediated endocytic traffic of LR11/SorLA alters APP intracellular distribution and amyloid- production.
Mol Biol Cell Volume: 23 Page(s): 2645 - 2657
07/01/2012 Authors: Herskowitz JH; Offe K; Deshpande A; Kahn RA; Levey AI; Lah JJ -
Using CSF biomarkers to replicate genetic associations in Alzheimer's disease.
Neurobiol Aging Volume: 33 Page(s): 1486.e9 - 1486.15
07/01/2012 Authors: Schott JM; ADNI Investigators -
Apolipoprotein E 2 and functional decline in amnestic mild cognitive impairment and Alzheimer disease.
Am J Geriatr Psychiatry Volume: 20 Page(s): 584 - 593
07/01/2012 Authors: Bonner-Jackson A; Okonkwo O; Tremont G; Alzheimers Disease Neuroimaging Initiative -
Comparative distribution of protein components of the A20 ubiquitin-editing complex in normal human brain.
Neurosci Lett Volume: 520 Page(s): 104 - 109
06/27/2012 Authors: Pranski EL; Van Sanford CD; Dalal NV; Orr AL; Karmali D; Cooper DS; Costa N; Heilman CJ; Gearing M; Lah JJ -
Identifying disease sensitive and quantitative trait-relevant biomarkers from multidimensional heterogeneous imaging genetics data via sparse multimodal multitask learning.
Volume: 28 Page(s): i127 - i136
06/15/2012 Authors: Wang H; Nie F; Huang H; Risacher SL; Saykin AJ; Shen L; Alzheimer's Disease Neuroimaging Initiative -
Gender modulates the APOE 4 effect in healthy older adults: convergent evidence from functional brain connectivity and spinal fluid tau levels.
J Neurosci Volume: 32 Page(s): 8254 - 8262
06/13/2012 Authors: Damoiseaux JS; Seeley WW; Zhou J; Shirer WR; Coppola G; Karydas A; Rosen HJ; Miller BL; Kramer JH; Greicius MD -
Functional electrical stimulation for the treatment of lower extremity dystonia.
Parkinsonism Relat Disord Volume: 18 Page(s): 660 - 661
06/01/2012 Authors: Barrett MJ; Bressman SB; Levy OA; Fahn S; O'Dell MW -
Localized hippocampus measures are associated with Alzheimer pathology and cognition independent of total hippocampal volume.
Neurobiol Aging Volume: 33 Page(s): 1124.e31 - 1124.e41
06/01/2012 Authors: Carmichael O; Xie J; Fletcher E; Singh B; DeCarli C; Alzheimer's Disease Neuroimaging Initiative -
The neuropathology of genetic Parkinson's disease.
Mov Disord Volume: 27 Page(s): 831 - 842
06/01/2012 Authors: Poulopoulos M; Levy OA; Alcalay RN -
Quantitative analysis of the detergent-insoluble brain proteome in frontotemporal lobar degeneration using SILAC internal standards.
J Proteome Res Volume: 11 Page(s): 2721 - 2738
05/04/2012 Authors: Seyfried NT; Gozal YM; Donovan LE; Herskowitz JH; Dammer EB; Xia Q; Ku L; Chang J; Duong DM; Rees HD -
Predicting missing biomarker data in a longitudinal study of Alzheimer disease.
Neurology Volume: 78 Page(s): 1376 - 1382
05/01/2012 Authors: Lo RY; Jagust WJ; Alzheimer's Disease Neuroimaging Initiative -
Neuronal RING finger protein 11 (RNF11) regulates canonical NF-B signaling.
J Neuroinflammation Volume: 9 Page(s): 67
04/16/2012 Authors: Pranski EL; Dalal NV; Herskowitz JH; Orr AL; Roesch LA; Fritz JJ; Heilman C; Lah JJ; Levey AI; Betarbet RS -
Identification of common variants associated with human hippocampal and intracranial volumes.
Nat Genet Volume: 44 Page(s): 552 - 561
04/15/2012 Authors: Stein JL; Medland SE; Vasquez AA; Hibar DP; Senstad RE; Winkler AM; Toro R; Appel K; Bartecek R; Bergmann -
Encephalopathy Responsive to Zolpidem.
Volume: 60 Page(s): S76 - S76
04/01/2012 Authors: Howard M; Rye D; Greene J; Levey AI -
Beta Amyloid, Tau, Neuroimaging, and Cognition: Sequence Modeling of Biomarkers for Alzheimer's Disease
Volume: 78
04/01/2012 Authors: Han SD; Gruhl J; Beckett L; Dodge H; Stricker N; Farias S; Mungas D -
Analysis of a membrane-enriched proteome from postmortem human brain tissue in Alzheimer's disease.
Proteomics Clin Appl Volume: 6 Page(s): 201 - 211
01/01/2012 Authors: Donovan LE; Higginbotham L; Dammer EB; Gearing M; Rees HD; Xia Q; Duong DM; Seyfried NT; Lah JJ; Levey AI -
Cerebrospinal Fluid beta-Amyloid 1-42 Solubility Is Influenced by Apolipoproteins E and J
Volume: 78
04/01/2012 Authors: Hu W; Basra S; Watts K; Glass J; Lah J; Levey A -
Brain Expression Genome-Wide Association Study (eGWAS) Identifies Human Disease-Associated Variants
Volume: 78
04/01/2012 Authors: Taner N; Zou F; Chai HS; Younkin C; Crook J; Pankratz V; Allen M; Carrasquillo M; Rowley C; Nair A -
Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans.
Proc Natl Acad Sci U S A Volume: 109 Page(s): 3985 - 3990
03/06/2012 Authors: Bakken TE; Roddey JC; Djurovic S; Akshoomoff N; Amaral DG; Bloss CS; Casey BJ; Chang L; Ernst TM; Gruen JR -
Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease.
Cell Stem Cell Volume: 10 Page(s): 244 - 258
03/02/2012 Authors: Ranganath SH; Levy O; Inamdar MS; Karp JM -
Does feature selection improve classification accuracy? Impact of sample size and feature selection on classification using anatomical magnetic resonance images.
Neuroimage Volume: 60 Page(s): 59 - 70
03/01/2012 Authors: Chu C; Hsu A-L; Chou K-H; Bandettini P; Lin C; Alzheimer's Disease Neuroimaging Initiative -
Empirical derivation of the reference region for computing diagnostic sensitive fluorodeoxyglucose ratios in Alzheimer's disease based on the ADNI sample.
Biochim Biophys Acta Volume: 1822 Page(s): 457 - 466
03/01/2012 Authors: Rasmussen JM; Lakatos A; van Erp TGM; Kruggel F; Keator DB; Fallon JT; Macciardi F; Potkin SG; Alzheimer's Disease Neuroimaging Initiative -
Detecting global and local hippocampal shape changes in Alzheimer's disease using statistical shape models.
Neuroimage Volume: 59 Page(s): 2155 - 2166
02/01/2012 Authors: Shen K-K; Fripp J; Mriaudeau F; Chtelat G; Salvado O; Bourgeat P; Alzheimer's Disease Neuroimaging Initiative -
BEaST: brain extraction based on nonlocal segmentation technique.
Neuroimage Volume: 59 Page(s): 2362 - 2373
02/01/2012 Authors: Eskildsen SF; Coup P; Fonov V; Manjn JV; Leung KK; Guizard N; Wassef SN; stergaard LR; Collins DL; Alzheimer's Disease Neuroimaging Initiative -
Individual subject classification for Alzheimer's disease based on incremental learning using a spatial frequency representation of cortical thickness data.
Neuroimage Volume: 59 Page(s): 2217 - 2230
02/01/2012 Authors: Cho Y; Seong J-K; Jeong Y; Shin SY; Alzheimer's Disease Neuroimaging Initiative -
MRI cortical thickness biomarker predicts AD-like CSF and cognitive decline in normal adults.
Neurology Volume: 78 Page(s): 84 - 90
01/10/2012 Authors: Dickerson BC; Wolk DA; Alzheimer's Disease Neuroimaging Initiative -
Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants.
PLoS Genet Volume: 8 Page(s): e1002707
01/01/2012 Authors: Zou F; Chai HS; Younkin CS; Allen M; Crook J; Pankratz VS; Carrasquillo MM; Rowley CN; Nair AA; Middha S -
Hypertension and Alzheimer disease: is there a link?
Epidemiology Volume: 23 Page(s): 176 - 177
01/01/2012 Authors: Steenland K; Levey AI; Goldstein FC -
The Transcription Factor ATF4 as a Neuroprotective Target in Parkinson Disease
Volume: 72 Page(s): S138 - S138
01/01/2012 Authors: Sun X; Greene LA; Levy OA -
Multivariate protein signatures of pre-clinical Alzheimer's disease in the Alzheimer's disease neuroimaging initiative (ADNI) plasma proteome dataset.
PLoS One Volume: 7 Page(s): e34341
01/01/2012 Authors: Johnstone D; Milward EA; Berretta R; Moscato P; Alzheimer's Disease Neuroimaging Initiative -
Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
PLoS One Volume: 7 Page(s): e50640
01/01/2012 Authors: Swaminathan S; Huentelman MJ; Corneveaux JJ; Myers AJ; Faber KM; Foroud T; Mayeux R; Shen L; Kim S; Turk M -
Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease.
PLoS One Volume: 7 Page(s): e50354
01/01/2012 Authors: Reitz C; Tosto G; Mayeux R; Luchsinger JA; NIA-LOAD/NCRAD Family Study Group; Alzheimer's Disease Neuroimaging Initiative -
Improved classification of Alzheimer's disease data via removal of nuisance variability.
PLoS One Volume: 7 Page(s): e31112
01/01/2012 Authors: Koikkalainen J; Plnen H; Mattila J; van Gils M; Soininen H; Ltjnen J; Alzheimer's Disease Neuroimaging Initiative -
Rates of decline in Alzheimer disease decrease with age.
PLoS One Volume: 7 Page(s): e42325
01/01/2012 Authors: Holland D; Desikan RS; Dale AM; McEvoy LK; Alzheimers Disease Neuroimaging Initiative -
Structural brain alterations before mild cognitive impairment in ADNI: validation of volume loss in a predefined antero-temporal region.
J Alzheimers Dis Volume: 31 Suppl 3 Page(s): S49 - S58
01/01/2012 Authors: Smith CD; Andersen AH; Gold BT; Alzheimer's Disease Neuroimaging Initiative -
Classification of structural MRI images in Alzheimer's disease from the perspective of ill-posed problems.
PLoS One Volume: 7 Page(s): e44877
01/01/2012 Authors: Casanova R; Hsu F-C; Espeland MA; Alzheimer's Disease Neuroimaging Initiative -
Plasma based markers of [11C] PiB-PET brain amyloid burden.
PLoS One Volume: 7 Page(s): e44260
01/01/2012 Authors: Kiddle SJ; Thambisetty M; Simmons A; Riddoch-Contreras J; Hye A; Westman E; Pike I; Ward M; Johnston C; Lupton MK -
Neuronal LR11 expression does not differentiate between clinically-defined Alzheimer's disease and control brains.
PLoS One Volume: 7 Page(s): e40527
01/01/2012 Authors: Sager KL; Wuu J; Herskowitz JH; Mufson EJ; Levey AI; Lah JJ -
Applications of Microfabrication and Microfluidic Techniques in Mesenchymal Stem Cell Research
Page(s): 69 - 95
01/01/2012 Authors: Majumder A; Dhawan J; Levy O; Karp JM -
Late-life depression as a risk factor for mild cognitive impairment or Alzheimer's disease in 30 US Alzheimer's disease centers.
J Alzheimers Dis Volume: 31 Page(s): 265 - 275
01/01/2012 Authors: Steenland K; Karnes C; Seals R; Carnevale C; Hermida A; Levey A -
Neurocognitive correlates of nocturnal oxygen desaturation in a memory clinic population.
J Clin Exp Neuropsychol Volume: 34 Page(s): 325 - 332
01/01/2012 Authors: Yamout K; Goldstein FC; Lah JJ; Levey AI; Bliwise DL -
Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination.
PLoS One Volume: 7 Page(s): e38658
01/01/2012 Authors: Dammer EB; Fallini C; Gozal YM; Duong DM; Rossoll W; Xu P; Lah JJ; Levey AI; Peng J; Bassell GJ -
Autosomal recessive causes likely in early-onset Alzheimer disease.
Arch Neurol Volume: 69 Page(s): 59 - 64
01/01/2012 Authors: Wingo TS; Lah JJ; Levey AI; Cutler DJ -
Paraoxonase-1 polymorphisms in Alzheimer's disease, Parkinson's disease, and AD-PD spectrum diseases.
Neurobiol Aging Volume: 33 Page(s): 204.e13 - 204.e15
01/01/2012 Authors: Wingo TS; Rosen A; Cutler DJ; Lah JJ; Levey AI -
Gephyrin Plaques Identified in Frontal Cortex of Alzheimer's Disease Brains
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01/01/2012 Authors: Hales CM; Rees H; Lah JJ; Levey AI; Wingo T -
Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration.
Mol Neurodegener Volume: 6 Page(s): 82
11/29/2011 Authors: Gozal YM; Seyfried NT; Gearing M; Glass JD; Heilman CJ; Wuu J; Duong DM; Cheng D; Xia Q; Rees HD -
Alzheimer disease biomarkers are associated with body mass index.
Neurology Volume: 77 Page(s): 1913 - 1920
11/22/2011 Authors: Vidoni ED; Townley RA; Honea RA; Burns JM; Alzheimer's Disease Neuroimaging Initiative -
An exploration of subgroups of mild cognitive impairment based on cognitive, neuropsychiatric and functional features: analysis of data from the National Alzheimer's Coordinating Center.
Am J Geriatr Psychiatry Volume: 19 Page(s): 940 - 950
11/01/2011 Authors: Hanfelt JJ; Wuu J; Sollinger AB; Greenaway MC; Lah JJ; Levey AI; Goldstein FC -
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging.
Nat Neurosci Volume: 14 Page(s): 1607 - 1616
10/30/2011 Authors: Szulwach KE; Li X; Li Y; Song C-X; Wu H; Dai Q; Irier H; Upadhyay AK; Gearing M; Levey AI -
Predicting MCI outcome with clinically available MRI and CSF biomarkers.
Neurology Volume: 77 Page(s): 1619 - 1628
10/25/2011 Authors: Heister D; Brewer JB; Magda S; Blennow K; McEvoy LK; Alzheimer's Disease Neuroimaging Initiative -
Longitudinal change of biomarkers in cognitive decline.
Arch Neurol Volume: 68 Page(s): 1257 - 1266
10/01/2011 Authors: Lo RY; Hubbard AE; Shaw LM; Trojanowski JQ; Petersen RC; Aisen PS; Weiner MW; Jagust WJ; Alzheimer's Disease Neuroimaging Initiative -
Akt as a victim, villain and potential hero in Parkinson's disease pathophysiology and treatment.
Cell Mol Neurobiol Volume: 31 Page(s): 969 - 978
10/01/2011 Authors: Greene LA; Levy O; Malagelada C -
-Hexachlorocyclohexane levels in serum and risk of Parkinson's disease.
Neurotoxicology Volume: 32 Page(s): 640 - 645
10/01/2011 Authors: Richardson JR; Roy A; Shalat SL; Buckley B; Winnik B; Gearing M; Levey AI; Factor SA; O'Suilleabhain P; German DC -
Nanowired three-dimensional cardiac patches.
Nat Nanotechnol Volume: 6 Page(s): 720 - 725
09/25/2011 Authors: Dvir T; Timko BP; Brigham MD; Naik SR; Karajanagi SS; Levy O; Jin H; Parker KK; Langer R; Kohane DS -
Mild cognitive impairment: baseline and longitudinal structural MR imaging measures improve predictive prognosis.
Radiology Volume: 259 Page(s): 834 - 843
06/01/2011 Authors: McEvoy LK; Holland D; Hagler DJ; Fennema-Notestine C; Brewer JB; Dale AM; Alzheimer's Disease Neuroimaging Initiative -
Alternative processing of -secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for -secretase dysfunction.
Ann Neurol Volume: 69 Page(s): 1026 - 1031
06/01/2011 Authors: Hata S; Fujishige S; Araki Y; Taniguchi M; Urakami K; Peskind E; Akatsu H; Araseki M; Yamamoto K; Martins RN -
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease.
Nat Genet Volume: 43 Page(s): 436 - 441
05/01/2011 Authors: Naj AC; Jun G; Beecham GW; Wang L-S; Vardarajan BN; Buros J; Gallins PJ; Buxbaum JD; Jarvik GP; Crane PK -
Functional polymorphisms of dopamine pathway genes (COMT, MAOB and DBH) in the development of Parkinson's disease: A study with multiple stratifications and risk factor adjustments
Volume: 26 Page(s): S319 - S319
05/01/2011 Authors: Xie T; Marder K; Tang Y; Levey A; Santella R; Tang M; Wang Q; Cubells J; Duan W; Clark L -
White matter hyperintensities and changes in white matter integrity in patients with Alzheimer's disease.
Neuroradiology Volume: 53 Page(s): 373 - 381
05/01/2011 Authors: Wang L; Goldstein FC; Levey AI; Lah JJ; Meltzer CC; Holder CA; Mao H -
A phase II trial of huperzine A in mild to moderate Alzheimer disease.
Neurology Volume: 76 Page(s): 1389 - 1394
04/19/2011 Authors: Rafii MS; Walsh S; Little JT; Behan K; Reynolds B; Ward C; Jin S; Thomas R; Aisen PS; Alzheimer's Disease Cooperative Study -
Polyubiquitin linkage profiles in three models of proteolytic stress suggest the etiology of Alzheimer disease.
J Biol Chem Volume: 286 Page(s): 10457 - 10465
03/25/2011 Authors: Dammer EB; Na CH; Xu P; Seyfried NT; Duong DM; Cheng D; Gearing M; Rees H; Lah JJ; Levey AI -
Factors Associated with 30-Day Readmission in Patients with Stroke and Cerebrovascular Disease
Volume: 76 Page(s): A147 - A147
03/01/2011 Authors: Nahab F; Takesaka J; Mailyan E; Judd L; Culler S; Webb A; Esper G; Frankel M; Glass J; Choi D -
Rho kinase II phosphorylation of the lipoprotein receptor LR11/SORLA alters amyloid-beta production.
J Biol Chem Volume: 286 Page(s): 6117 - 6127
02/25/2011 Authors: Herskowitz JH; Seyfried NT; Gearing M; Kahn RA; Peng J; Levey AI; Lah JJ -
Multi-method analysis of MRI images in early diagnostics of Alzheimer's disease.
PLoS One Volume: 6 Page(s): e25446
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Proteomic analysis of hippocampal dentate granule cells in frontotemporal lobar degeneration: application of laser capture technology.
Front Neurol Volume: 2 Page(s): 24
01/01/2011 Authors: Gozal YM; Dammer EB; Duong DM; Cheng D; Gearing M; Rees HD; Peng J; Lah JJ; Levey AI -
Phosphoproteomic analysis reveals site-specific changes in GFAP and NDRG2 phosphorylation in frontotemporal lobar degeneration.
J Proteome Res Volume: 9 Page(s): 6368 - 6379
12/03/2010 Authors: Herskowitz JH; Seyfried NT; Duong DM; Xia Q; Rees HD; Gearing M; Peng J; Lah JJ; Levey AI -
Highly efficient osteogenic differentiation of human mesenchymal stem cells by eradication of STAT3 signaling.
Int J Biochem Cell Biol Volume: 42 Page(s): 1823 - 1830
11/01/2010 Authors: Levy O; Ruvinov E; Reem T; Granot Y; Cohen S -
The Stress Protein RTP801 is Required for Neuronal Death Induced by Alpha-Synuclein
Volume: 25 Page(s): S620 - S620
09/15/2010 Authors: Levy OA; Malagelada C; Greene LA -
Differential effects of allosteric M(1) muscarinic acetylcholine receptor agonists on receptor activation, arrestin 3 recruitment, and receptor downregulation.
ACS Chem Neurosci Volume: 1 Page(s): 542 - 551
08/18/2010 Authors: Davis AA; Heilman CJ; Brady AE; Miller NR; Fuerstenau-Sharp M; Hanson BJ; Lindsley CW; Conn PJ; Lah JJ; Levey AI -
Genome-wide association study identifies a sequence variant within the DAB2IP gene conferring susceptibility to abdominal aortic aneurysm.
Nat Genet Volume: 42 Page(s): 692 - 697
08/01/2010 Authors: Gretarsdottir S; Baas AF; Thorleifsson G; Holm H; den Heijer M; de Vries J-PPM; Kranendonk SE; Zeebregts CJAM; van Sterkenburg SM; Geelkerken RH -
Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers.
Ann Neurol Volume: 68 Page(s): 220 - 230
08/01/2010 Authors: Gandy S; Simon AJ; Steele JW; Lublin AL; Lah JJ; Walker LC; Levey AI; Krafft GA; Levy E; Checler F -
RTN/Nogo in forming Alzheimer's neuritic plaques.
Neurosci Biobehav Rev Volume: 34 Page(s): 1201 - 1206
07/01/2010 Authors: Prior M; Shi Q; Hu X; He W; Levey A; Yan R -
Synthesis and In Vitro Evaluation of Imidazo[1,2-b]pyridazines as Ligands for -Amyloid Plaques.
ACS Med Chem Lett Volume: 1 Page(s): 80 - 84
05/13/2010 Authors: Zeng F; Alagille D; Tamagnan GD; Ciliax BJ; Levey AI; Goodman MM -
Tc-99m-albumin nanocolloid joint scintigraphy in rheumatoid arthritis patients who are in clinical remission - is remission real?
CLINICAL AND EXPERIMENTAL RHEUMATOLOGY Volume: 28 Page(s): 360 - 364
05/01/2010 Authors: Tishler M; Lysyy O; Levy O; Volkov O; Golan H -
Multiplex SILAC analysis of a cellular TDP-43 proteinopathy model reveals protein inclusions associated with SUMOylation and diverse polyubiquitin chains.
Mol Cell Proteomics Volume: 9 Page(s): 705 - 718
04/01/2010 Authors: Seyfried NT; Gozal YM; Dammer EB; Xia Q; Duong DM; Cheng D; Lah JJ; Levey AI; Peng J -
Deletion of M1 muscarinic acetylcholine receptors increases amyloid pathology in vitro and in vivo.
J Neurosci Volume: 30 Page(s): 4190 - 4196
03/24/2010 Authors: Davis AA; Fritz JJ; Wess J; Lah JJ; Levey AI -
Functional Polymorphisms of Human Dopamine Pathway Genes COMT, DBH and MAOS: A Pilot SNP Study of Single Gene Locus and Gene-Gene Interaction in Parkinson Disease
Volume: 74 Page(s): A254 - A254
03/02/2010 Authors: Xie T; Levey A; Tang Y; Cubells J; Duan W -
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
Nat Genet Volume: 42 Page(s): 234 - 239
03/01/2010 Authors: Van Deerlin VM; Sleiman PMA; Martinez-Lage M; Chen-Plotkin A; Wang L-S; Graff-Radford NR; Dickson DW; Rademakers R; Boeve BF; Grossman M -
Mild cognitive impairment in Parkinson's disease: subtypes and motor characteristics.
Parkinsonism Relat Disord Volume: 16 Page(s): 177 - 180
03/01/2010 Authors: Sollinger AB; Goldstein FC; Lah JJ; Levey AI; Factor SA -
A subpopulation of neuronal M4 muscarinic acetylcholine receptors plays a critical role in modulating dopamine-dependent behaviors.
J Neurosci Volume: 30 Page(s): 2396 - 2405
02/10/2010 Authors: Jeon J; Dencker D; Wrtwein G; Woldbye DPD; Cui Y; Davis AA; Levey AI; Schtz G; Sager TN; Mrk A -
The impact of vascular comorbidities on qualitative error analysis of executive impairment in Alzheimer's disease.
J Int Neuropsychol Soc Volume: 16 Page(s): 77 - 83
01/01/2010 Authors: Lamar M; Libon DJ; Ashley AV; Lah JJ; Levey AI; Goldstein FC -
Factors affecting survival of patients with neurodegenerative disease.
Neuroepidemiology Volume: 35 Page(s): 28 - 35
01/01/2010 Authors: Steenland K; MacNeil J; Seals R; Levey A -
A selective allosteric potentiator of the M1 muscarinic acetylcholine receptor increases activity of medial prefrontal cortical neurons and restores impairments in reversal learning.
J Neurosci Volume: 29 Page(s): 14271 - 14286
11/11/2009 Authors: Shirey JK; Brady AE; Jones PJ; Davis AA; Bridges TM; Kennedy JP; Jadhav SB; Menon UN; Xiang Z; Watson ML -
Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer's disease.
J Proteome Res Volume: 8 Page(s): 5069 - 5079
11/01/2009 Authors: Gozal YM; Duong DM; Gearing M; Cheng D; Hanfelt JJ; Funderburk C; Peng J; Lah JJ; Levey AI -
Implanted neural electrodes cause chronic, local inflammation that is correlated with local neurodegeneration.
J Neural Eng Volume: 6 Page(s): 056003
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Interaction of Akt-phosphorylated SRPK2 with 14-3-3 mediates cell cycle and cell death in neurons.
J Biol Chem Volume: 284 Page(s): 24512 - 24525
09/04/2009 Authors: Jang S-W; Liu X; Fu H; Rees H; Yepes M; Levey A; Ye K -
Is ApoE epsilon4 associated with cognitive functioning in African Americans diagnosed with Alzheimer Disease? An exploratory study.
South Med J Volume: 102 Page(s): 890 - 893
09/01/2009 Authors: Mount DL; Ashley AV; Lah JJ; Levey AI; Goldstein FC -
Prevascularization of cardiac patch on the omentum improves its therapeutic outcome.
Proc Natl Acad Sci U S A Volume: 106 Page(s): 14990 - 14995
09/01/2009 Authors: Dvir T; Kedem A; Ruvinov E; Levy O; Freeman I; Landa N; Holbova R; Feinberg MS; Dror S; Etzion Y -
White Matter Integrity and Episodic Memory Performance in Mild Cognitive Impairment: A Diffusion Tensor Imaging Study.
Brain Imaging Behav Volume: 3 Page(s): 132 - 141
06/01/2009 Authors: Goldstein FC; Mao H; Wang L; Ni C; Lah JJ; Levey AI -
Alterations in cortical thickness and white matter integrity in mild cognitive impairment measured by whole-brain cortical thickness mapping and diffusion tensor imaging.
Volume: 30 Page(s): 893 - 899
05/01/2009 Authors: Wang L; Goldstein FC; Veledar E; Levey AI; Lah JJ; Meltzer CC; Holder CA; Mao H -
Cell death pathways in Parkinson's disease: proximal triggers, distal effectors, and final steps.
Apoptosis Volume: 14 Page(s): 478 - 500
04/01/2009 Authors: Levy OA; Malagelada C; Greene LA -
Non-Verbal Memory Performance is Associated with Conversion to Dementia Within 1 Year: A Prospective Study of MCI Using Computerized Cognitive Assessment
Volume: 57 Page(s): S194 - S195
03/01/2009 Authors: Dwolatzky T; Doniger GM; Goldstein FC; Simon ES; Levey AI; Lah J; Friger MD -
Non-Verbal Memory Performance is Associated with Conversion to Dementia Within 1 Year: A Prospective Study of MCI Using Computerized Cognitive Assessment
AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY Volume: 17 Page(s): A71 - A72
03/01/2009 Authors: Simon ES; Dwolatzky T; Goldstein FC; Doniger GM; Levey AI; Lah JJ; Friger MD -
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction.
Nat Genet Volume: 41 Page(s): 342 - 347
03/01/2009 Authors: Gudbjartsson DF; Bjornsdottir US; Halapi E; Helgadottir A; Sulem P; Jonsdottir GM; Thorleifsson G; Helgadottir H; Steinthorsdottir V; Stefansson H -
SPE-39 family proteins interact with the HOPS complex and function in lysosomal delivery.
Mol Biol Cell Volume: 20 Page(s): 1223 - 1240
02/01/2009 Authors: Zhu G-D; Salazar G; Zlatic SA; Fiza B; Doucette MM; Heilman CJ; Levey AI; Faundez V; L'hernault SW -
Neurobiology of Alzheimer's Disease
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Eye tracking during a visual paired comparison task as a predictor of early dementia.
Am J Alzheimers Dis Other Demen Volume: 24 Page(s): 258 - 266
01/01/2009 Authors: Crutcher MD; Calhoun-Haney R; Manzanares CM; Lah JJ; Levey AI; Zola SM -
Recent trends in Alzheimer disease mortality in the United States, 1999 to 2004.
Alzheimer Dis Assoc Disord Volume: 23 Page(s): 165 - 170
01/01/2009 Authors: Steenland K; MacNeil J; Vega I; Levey A -
Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease.
J Neurosci Volume: 28 Page(s): 12877 - 12886
11/26/2008 Authors: Dodson SE; Andersen OM; Karmali V; Fritz JJ; Cheng D; Peng J; Levey AI; Willnow TE; Lah JJ -
Development of a rapid screening instrument for mild cognitive impairment and undiagnosed dementia.
J Alzheimers Dis Volume: 15 Page(s): 419 - 427
11/01/2008 Authors: Steenland NK; Auman CM; Patel PM; Bartell SM; Goldstein FC; Levey AI; Lah JJ -
Novel selective allosteric activator of the M1 muscarinic acetylcholine receptor regulates amyloid processing and produces antipsychotic-like activity in rats.
J Neurosci Volume: 28 Page(s): 10422 - 10433
10/08/2008 Authors: Jones CK; Brady AE; Davis AA; Xiang Z; Bubser M; Tantawy MN; Kane AS; Bridges TM; Kennedy JP; Bradley SR -
Association of GSK3B with Alzheimer disease and frontotemporal dementia.
Arch Neurol Volume: 65 Page(s): 1368 - 1374
10/01/2008 Authors: Schaffer BAJ; Bertram L; Miller BL; Mullin K; Weintraub S; Johnson N; Bigio EH; Mesulam M; Wiedau-Pazos M; Jackson GR -
Mild cognitive impairment in Parkinson's disease: Clinical and motor characteristics
Volume: 23 Page(s): 686 - 686
10/01/2008 Authors: Sollinger AB; Goldstein F; Lah J; Levey A; Factor S -
Fas-associated factor 1 and Parkinson's disease.
Neurobiol Dis Volume: 31 Page(s): 309 - 315
09/01/2008 Authors: Betarbet R; Anderson LR; Gearing M; Hodges TR; Fritz JJ; Lah JJ; Levey AI -
Phosphoproteomic analysis of human brain by calcium phosphate precipitation and mass spectrometry.
J Proteome Res Volume: 7 Page(s): 2845 - 2851
07/01/2008 Authors: Xia Q; Cheng D; Duong DM; Gearing M; Lah JJ; Levey AI; Peng J -
Proteomic identification of novel proteins associated with Lewy bodies.
Front Biosci Volume: 13 Page(s): 3850 - 3856
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MEDI 253-Subtype-selective allosteric modulation of the M1 and M4 muscarinic receptors
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04/06/2008 Authors: Bridges TM; Jones CK; Brady A; Marlo JE; Rodriguez AL; Niswender CM; Sheffler D; Kennedy P; Williams R; Orton D -
Molecular and behavioral phenotypes caused by selective disruption of M4 muscarinic acetylcholine receptors in D1 dopamine receptor-expressing cells
FASEB JOURNAL Volume: 22
04/01/2008 Authors: Jeon J; Woertwein G; Fink-Jensen A; Woldbye DPD; Schulein C; Schuetz G; Davis AA; Rees HD; Levey AI; Li C -
A single nucleotide polymorphism (SNP) at DBH is associated with Alzheimer disease in European-American subjects
Volume: 63 Page(s): 92S - 92S
04/01/2008 Authors: Tang Y; Lah J; Rosen A; Levey A; Cubells JF -
Non-verbal memory performance is associated with conversion to dementia within 1 year: A prospective study of MCI using computerized cognitive assessment
Volume: 70 Page(s): A279 - A279
03/11/2008 Authors: Simon E; Dwolatzky T; Goldstein F; Doniger GM; Levey A; Lah J; Friger MD -
Development of transgenic rats producing human beta-amyloid precursor protein as a model for Alzheimer's disease: transgene and endogenous APP genes are regulated tissue-specifically.
BMC Neurosci Volume: 9 Page(s): 28
02/26/2008 Authors: Agca C; Fritz JJ; Walker LC; Levey AI; Chan AW; Lah JJ; Agca Y -
The same sequence variant on 9p21 associates with myocardial infarction, abdominal aortic aneurysm and intracranial aneurysm.
Nat Genet Volume: 40 Page(s): 217 - 224
02/01/2008 Authors: Helgadottir A; Thorleifsson G; Magnusson KP; Grtarsdottir S; Steinthorsdottir V; Manolescu A; Jones GT; Rinkel GJE; Blankensteijn JD; Ronkainen A -
Geographical differences in the occurrence of Alzheimer's disease mortality: United States versus Puerto Rico.
Am J Alzheimers Dis Other Demen Volume: 23 Page(s): 462 - 469
01/01/2008 Authors: Figueroa R; Steenland K; MacNeil JR; Levey AI; Vega IE -
Levoclopa-responsive camptocormia in a patient with parkinsonism and severe autonomic failure
Volume: 23 Page(s): S273 - S273
01/01/2008 Authors: Levy OA; Weimer LH; Mazzoni P -
Mint3/X11gamma is an ADP-ribosylation factor-dependent adaptor that regulates the traffic of the Alzheimer's Precursor protein from the trans-Golgi network.
Mol Biol Cell Volume: 19 Page(s): 51 - 64
01/01/2008 Authors: Shrivastava-Ranjan P; Faundez V; Fang G; Rees H; Lah JJ; Levey AI; Kahn RA -
Cognitive performance and plasma levels of homocysteine, vitamin B12, folate and lipids in patients with Alzheimer disease.
Dement Geriatr Cogn Disord Volume: 26 Page(s): 384 - 390
01/01/2008 Authors: Li L; Cao D; Desmond R; Rahman A; Lah JJ; Levey AI; Zamrini E -
Signal transducer and activator of transcription 3-A key molecular switch for human mesenchymal stem cell proliferation.
Int J Biochem Cell Biol Volume: 40 Page(s): 2606 - 2618
01/01/2008 Authors: Levy O; Dvir T; Tsur-Gang O; Granot Y; Cohen S -
Bcl-6 predicts improved prognosis in primary central nervous system lymphoma.
Cancer Volume: 112 Page(s): 151 - 156
01/01/2008 Authors: Levy O; Deangelis LM; Filippa DA; Panageas KS; Abrey LE -
Effects of hypertension and hypercholesterolemia on cognitive functioning in patients with alzheimer disease.
Alzheimer Dis Assoc Disord Volume: 22 Page(s): 336 - 342
01/01/2008 Authors: Goldstein FC; Ashley AV; Endeshaw YW; Hanfelt J; Lah JJ; Levey AI -
Neuronal LR11/sorLA expression is reduced in mild cognitive impairment.
Ann Neurol Volume: 62 Page(s): 640 - 647
12/01/2007 Authors: Sager KL; Wuu J; Leurgans SE; Rees HD; Gearing M; Mufson EJ; Levey AI; Lah JJ -
Evidence of shared risk for Alzheimer's disease and Parkinson's disease using family history.
Neurogenetics Volume: 8 Page(s): 263 - 270
11/01/2007 Authors: Rosen AR; Steenland NK; Hanfelt J; Factor SA; Lah JJ; Levey AI -
PARK10 candidate RNF11 is expressed by vulnerable neurons and localizes to Lewy bodies in Parkinson disease brain.
J Neuropathol Exp Neurol Volume: 66 Page(s): 955 - 964
10/01/2007 Authors: Anderson LR; Betarbet R; Gearing M; Gulcher J; Hicks AA; Stefnsson K; Lah JJ; Levey AI -
Activation of the ERK1/2 cascade via pulsatile interstitial fluid flow promotes cardiac tissue assembly.
Tissue Eng Volume: 13 Page(s): 2185 - 2193
09/01/2007 Authors: Dvir T; Levy O; Shachar M; Granot Y; Cohen S -
Influence of sleep disordered breathing on cognitive functioning among elderly with cognitive compromise
ARCHIVES OF CLINICAL NEUROPSYCHOLOGY Volume: 22 Page(s): 817 - 817
09/01/2007 Authors: Yamout KZ; Bliwise DL; Goldstein FC; Wood-Siverio C; Lah JJ; Levey A -
Daytime sleepiness and functional impairment in Alzheimer disease.
Am J Geriatr Psychiatry Volume: 15 Page(s): 620 - 626
07/01/2007 Authors: Lee JH; Bliwise DL; Ansari FP; Goldstein FC; Cellar JS; Lah JJ; Levey AI -
Production of antisera using fusion proteins.
Curr Protoc Neurosci Volume: Chapter 5 Page(s): Unit - 5.7
07/01/2007 Authors: Dodson SE; Heilman CJ; Kahn RA; Levey AI -
Deficits in acetylcholine homeostasis, receptors and behaviors in choline transporter heterozygous mice.
Genes Brain Behav Volume: 6 Page(s): 411 - 424
07/01/2007 Authors: Bazalakova MH; Wright J; Schneble EJ; McDonald MP; Heilman CJ; Levey AI; Blakely RD -
A common variant on chromosome 9p21 affects the risk of myocardial infarction.
Science Volume: 316 Page(s): 1491 - 1493
06/08/2007 Authors: Helgadottir A; Thorleifsson G; Manolescu A; Gretarsdottir S; Blondal T; Jonasdottir A; Jonasdottir A; Sigurdsson A; Baker A; Palsson A -
Transgenic mice overexpressing reticulon 3 develop neuritic abnormalities.
EMBO J Volume: 26 Page(s): 2755 - 2767
06/06/2007 Authors: Hu X; Shi Q; Zhou X; He W; Yi H; Yin X; Gearing M; Levey A; Yan R -
Plaque amyloid per se plays no detectable role in timing of onset or initial severity of cognitive dysfunction in a mouse model of Alzheimer's
Volume: 68 Page(s): A188 - A189
03/20/2007 Authors: Gandy S; Lah J; Walker L; Kufahamu T; Pedrini S; Gieringer T; Levy E; Levey A; Abel T; Ehrlich M -
A case of Creutzfeldt-Jakob disease with Alien limb syndrome and elevated thyroid autoantibodies
Volume: 68 Page(s): A141 - A141
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Selective enrichment of DJ-1 protein in primate striatal neuronal processes: implications for Parkinson's disease.
J Comp Neurol Volume: 500 Page(s): 585 - 599
01/20/2007 Authors: Olzmann JA; Bordelon JR; Muly EC; Rees HD; Levey AI; Li L; Chin L-S -
The role of LR11/SORL1 in Alzheimer's disease pathogenesis
Volume: 62 Page(s): S7 - S7
01/01/2007 Authors: Lah JJ; Offe K; Dodson SE; Sager KL; Khoogar L; Levey AI -
Genetic investigation in frontotemporal dementia and Alzheimer's disease: The GIFT study
Volume: 62 Page(s): S52 - S52
01/01/2007 Authors: Coppola G; Miller BL; Chui H; Varpetian A; Levey A; Cotman CW; DeCarli C; Mendez MF; Bartzokis G; Kukull WA -
The National Alzheimer's Coordinating Center (NACC) database: the Uniform Data Set.
Alzheimer Dis Assoc Disord Volume: 21 Page(s): 249 - 258
01/01/2007 Authors: Beekly DL; Ramos EM; Lee WW; Deitrich WD; Jacka ME; Wu J; Hubbard JL; Koepsell TD; Morris JC; Kukull WA -
Changes in expression and distribution of LR11/Sorla distinguish between sporadic and genetic forms of Alzheimer's disease
Volume: 60 Page(s): 642 - 642
11/01/2006 Authors: Lah JJ; Dodson SE; Khoogar L; Mufson EJ; Levey AI -
Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14.
J Neurosci Volume: 26 Page(s): 11423 - 11431
11/01/2006 Authors: Crimmins S; Jin Y; Wheeler C; Huffman AK; Chapman C; Dobrunz LE; Levey A; Roth KA; Wilson JA; Wilson SM -
Elevated levels of dieldrin are associated with Parkinson's disease
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Volume: 232 Page(s): 647 - 647
09/10/2006 Authors: Pennell KD; Hatcher JM; Caudle WM; Richardson JR; Gearing M; Levey AI; Jones DP; Miller GW -
LR11/SorLA expression is reduced in sporadic Alzheimer disease but not in familial Alzheimer disease.
J Neuropathol Exp Neurol Volume: 65 Page(s): 866 - 872
09/01/2006 Authors: Dodson SE; Gearing M; Lippa CF; Montine TJ; Levey AI; Lah JJ -
Essential tremor phenotyping and molecular genetics: ET database cases and a new large pedigree
Volume: 21 Page(s): 1556 - 1556
09/01/2006 Authors: Rosen AR; Levey AI; Bouzyk M; Wichmann T; Factor SA; Testa CM -
Elongation factor 1A family regulates the recycling of the M4 muscarinic acetylcholine receptor.
Neurochem Res Volume: 31 Page(s): 975 - 988
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Rat Schwann cells express M1-M4 muscarinic receptor subtypes.
J Neurosci Res Volume: 84 Page(s): 97 - 105
07/01/2006 Authors: Loreti S; Vilar MT; Visentin S; Rees H; Levey AI; Tata AM -
Mild cognitive impairment: an opportunity to identify patients at high risk for progression to Alzheimer's disease.
Clin Ther Volume: 28 Page(s): 991 - 1001
07/01/2006 Authors: Levey A; Lah J; Goldstein F; Steenland K; Bliwise D -
Arginine-vasopressin activates the JAK-STAT pathway in vascular smooth muscle cells.
J Biol Chem Volume: 281 Page(s): 15597 - 15604
06/09/2006 Authors: Levy O; Granot Y -
Glycogen synthase kinase 3beta and Alzheimer's disease: pathophysiological and therapeutic significance.
Cell Mol Life Sci Volume: 63 Page(s): 1226 - 1235
06/01/2006 Authors: Balaraman Y; Limaye AR; Levey AI; Srinivasan S -
Synthesis and evaluation of two 18F-labeled imidazo[1,2-a]pyridine analogues as potential agents for imaging beta-amyloid in Alzheimer's disease.
Bioorg Med Chem Lett Volume: 16 Page(s): 3015 - 3018
06/01/2006 Authors: Zeng F; Southerland JA; Voll RJ; Votaw JR; Williams L; Ciliax BJ; Levey AI; Goodman MM -
Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases.
J Biol Chem Volume: 281 Page(s): 10816 - 10824
04/21/2006 Authors: Choi J; Sullards MC; Olzmann JA; Rees HD; Weintraub ST; Bostwick DE; Gearing M; Levey AI; Chin L-S; Li L -
Bcl-6 expression predicts improved relapse-free survival in primary central nervous system lyrnphoma
Volume: 66 Page(s): A337 - A338
03/14/2006 Authors: Levy O; DeAngelis L; Filippa D; Abrey L -
The lipoprotein receptor LR11 regulates amyloid beta production and amyloid precursor protein traffic in endosomal compartments.
J Neurosci Volume: 26 Page(s): 1596 - 1603
02/01/2006 Authors: Offe K; Dodson SE; Shoemaker JT; Fritz JJ; Gearing M; Levey AI; Lah JJ -
A variant of the gene encoding leukotriene A4 hydrolase confers ethnicity-specific risk of myocardial infarction.
Nat Genet Volume: 38 Page(s): 68 - 74
01/01/2006 Authors: Helgadottir A; Manolescu A; Helgason A; Thorleifsson G; Thorsteinsdottir U; Gudbjartsson DF; Gretarsdottir S; Magnusson KP; Gudmundsson G; Hicks A -
Merger of laser capture microdissection and mass spectrometry: a window into the amyloid plaque proteome.
Methods Enzymol Volume: 412 Page(s): 77 - 93
01/01/2006 Authors: Gozal YM; Cheng D; Duong DM; Lah JJ; Levey AI; Peng J -
Essential tremor phenotyping and molecular genetics: Database cases and a new large pedigree
Volume: 21 Page(s): S405 - S405
01/01/2006 Authors: Testa CM; Rosen AR; Wichmann T; Levey AI; Bouzyk M; Factor SA -
LR11 regulates intracellular amyloid precursor protein traffic and amyloid accumulation in Alzheimer's disease
Volume: 58
12/01/2005 Authors: Lah JJ; Dodson SE; Offe K; Shoemaker JT; Levey AI -
The effect of whiplash injury on the appearance of fibromyalgia.
Volume: 52 Page(s): S78 - S78
09/01/2005 Authors: Levy O; Maslakov I; Amit-Vazina M; Tishler M -
Vitamin E and donepezil for the treatment of mild cognitive impairment.
N Engl J Med Volume: 352 Page(s): 2379 - 2388
06/09/2005 Authors: Petersen RC; Thomas RG; Grundman M; Bennett D; Doody R; Ferris S; Galasko D; Jin S; Kaye J; Levey A -
Concomitant Alzheimer's disease and frontotemporal dementia-motor neuron disease subtype: A common neuropathologic phenomenon.
Volume: 64 Page(s): 433 - 433
05/01/2005 Authors: Gearing M; Lah JJ; Levey AI -
Severe frontotemporal glial pathology and mild hippocampal degeneration associated with the P301L MAPT mutation: Study of a previously unreported family.
Volume: 64 Page(s): 434 - 434
05/01/2005 Authors: Spina S; Murrell JR; Gearing M; Levey A; Mirra S; Yamaguchi K; Ghetti B; Lah J -
Donepezil and vitamin E in mild cognitive impairment.
Volume: 53 Page(s): S14 - S14
04/01/2005 Authors: Petersen RC; Thal LJ; Grundman M; Thomas RG; Bennett D; Doody R; Ferris S; Galask D; Kaye J; Levey A -
Oxidative modifications and aggregation of Cu,Zn-superoxide dismutase associated with Alzheimer and Parkinson diseases.
J Biol Chem Volume: 280 Page(s): 11648 - 11655
03/25/2005 Authors: Choi J; Rees HD; Weintraub ST; Levey AI; Chin L-S; Li L -
Hypertension and cognitive performance in African Americans with Alzheimer disease.
Neurology Volume: 64 Page(s): 899 - 901
03/08/2005 Authors: Goldstein FC; Ashley AV; Freedman LJ; Penix L; Lah JJ; Hanfelt J; Levey AI -
Feasibility of ambulatory overnight oximetry in consecutive patients in a dementia clinic.
J Am Geriatr Soc Volume: 53 Page(s): 545 - 546
03/01/2005 Authors: Bliwise DL; Lee J-H; Wood-Siverio C; Cellar JS; Lah JJ; Levey AI -
Common pattern of deficit in a multinational MCI cohort identified by objective computerized cognitive assessment
INTERNATIONAL PSYCHOGERIATRICS Volume: 17 Page(s): 252 - 253
01/01/2005 Authors: Dwolatzky T; Doniger G; Simon E; Goldstein F; Levey A; Lah J -
Daytime sleepiness associated with cognitive and functional impairments in Alzheimer's disease (AD)
Volume: 28 Page(s): A347 - A347
01/01/2005 Authors: Lee JH; Bliwise DL; Ansari FP; Goldstein FG; Cellar JS; Lah JJ; Levey AI -
Synaptic and extrasynaptic GABA-A and GABA-B receptors in the globus pallidus: an electron microscopic immunogold analysis in monkeys.
Neuroscience Volume: 131 Page(s): 917 - 933
01/01/2005 Authors: Charara A; Pare J-F; Levey AI; Smith Y -
The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine.
Psychopharmacology (Berl) Volume: 177 Page(s): 207 - 216
12/01/2004 Authors: Weiner DM; Meltzer HY; Veinbergs I; Donohue EM; Spalding TA; Smith TT; Mohell N; Harvey SC; Lameh J; Nash N -
Proteomic characterization of postmortem amyloid plaques isolated by laser capture microdissection.
J Biol Chem Volume: 279 Page(s): 37061 - 37068
08/27/2004 Authors: Liao L; Cheng D; Wang J; Duong DM; Losik TG; Gearing M; Rees HD; Lah JJ; Levey AI; Peng J -
Loss of apolipoprotein E receptor LR11 in Alzheimer disease.
Arch Neurol Volume: 61 Page(s): 1200 - 1205
08/01/2004 Authors: Scherzer CR; Offe K; Gearing M; Rees HD; Fang G; Heilman CJ; Schaller C; Bujo H; Levey AI; Lah JJ -
The "Mini-Cog" as a screen for dementia: Validation in an African American population
Volume: 25 Page(s): S131 - S132
07/01/2004 Authors: Ashley AV; Flacker J; Goldstein FC; Freedman LJ; Lah JJ; Levey AI -
Functional abilities in patients with mild cognitive impairment versus Alzheimer's disease and normal controls
Volume: 25 Page(s): S100 - S100
07/01/2004 Authors: Goldstein FC; Ashley AV; Freedman LJ; Cellar J; Harrison J; Lah JJ; Levey AI -
APOE4 genotype and sleep APNEA in Alzheimer's disease: Initial studies
Volume: 25 Page(s): S302 - S302
07/01/2004 Authors: Bliwise DL; Wood-Siverio C; Saunders DD; Greer SG; Hitchcock SE; Cellar J; Levey AI -
Quantification of LR11 expression in mild cognitive impairment, a human model for early Alzheimer's disease
Volume: 25 Page(s): S439 - S439
07/01/2004 Authors: Sager KL; Lah JJ; Levey AI; Rees HD; Mufson EJ; Bennett DA; Wuu J; Leurgans S -
Intermittent hypoxic insults occurring during a period of critical brain development reduce the expression of insoluble beta amyloid within the hippocampus
Volume: 25 Page(s): S166 - S166
07/01/2004 Authors: Jones KA; Carter S; Shoemaker JT; Solomon IG; Lah J; Levey A; Decker MJ -
Effect of targeted domain deletions on LR11-mediated regulation of extracellular A beta levels
Volume: 25 Page(s): S440 - S440
07/01/2004 Authors: Offe K; Williams TJ; Fang GF; Lah JJ; Levey AI -
Examining the role of the APOE receptor LR11 in the etiopathology of Alzheimer's disease
Volume: 25 Page(s): S441 - S441
07/01/2004 Authors: Dodson SE; Offe K; Carter SC; Shoemaker JT; Fan GF; Lah JJ; Levey AI -
RGS2 binds directly and selectively to the M1 muscarinic acetylcholine receptor third intracellular loop to modulate Gq/11alpha signaling.
J Biol Chem Volume: 279 Page(s): 21248 - 21256
05/14/2004 Authors: Bernstein LS; Ramineni S; Hague C; Cladman W; Chidiac P; Levey AI; Hepler JR -
Reduced expression of the multifunctional apolipoprotein E receptor LR11 plays an important role in Alzheimer's disease pathogenesis.
Volume: 63 Page(s): 553 - 553
05/01/2004 Authors: Gearing M; Lah JJ; Sager KL; Offer K; Dodson SE; Carter SC; Bennett DA; Mufson EJ; Levey AI -
Oxidative modifications and down-regulation of ubiquitin carboxyl-terminal hydrolase L1 associated with idiopathic Parkinson's and Alzheimer's diseases.
J Biol Chem Volume: 279 Page(s): 13256 - 13264
03/26/2004 Authors: Choi J; Levey AI; Weintraub ST; Rees HD; Gearing M; Chin L-S; Li L -
Is xanthine oxidase a factor in Alzheimer's dementia?
Volume: 18 Page(s): A933 - A933
03/24/2004 Authors: von Deutsch DA; Levey AI; Royal W; Abukhalaf IK; Socci RR; Silvestrov NA -
Familial Parkinson's disease-associated L166P mutation disrupts DJ-1 protein folding and function.
J Biol Chem Volume: 279 Page(s): 8506 - 8515
02/27/2004 Authors: Olzmann JA; Brown K; Wilkinson KD; Rees HD; Huai Q; Ke H; Levey AI; Li L; Chin L-S -
Plasma testosterone levels in Alzheimer and Parkinson diseases.
Neurology Volume: 62 Page(s): 411 - 413
02/10/2004 Authors: Okun MS; DeLong MR; Hanfelt J; Gearing M; Levey A -
Immunohistochemical localization of proteins in the nervous system.
Curr Protoc Neurosci Volume: Chapter 1 Page(s): Unit - 1.2
02/01/2004 Authors: Volpicelli-Daley LA; Levey A -
The zinc transporter ZnT3 interacts with AP-3 and it is preferentially targeted to a distinct synaptic vesicle subpopulation.
Mol Biol Cell Volume: 15 Page(s): 575 - 587
02/01/2004 Authors: Salazar G; Love R; Werner E; Doucette MM; Cheng S; Levey A; Faundez V -
Subpopulations of rat dorsal root ganglion neurons express active vesicular acetylcholine transporter.
J Neurosci Res Volume: 75 Page(s): 194 - 202
01/15/2004 Authors: Tata AM; De Stefano ME; Srubek Tomassy G; Vilar MT; Levey AI; Biagioni S -
Muscarinic acetylcholine receptor subtypes in cerebral cortex and hippocampus.
Prog Brain Res Volume: 145 Page(s): 59 - 66
01/01/2004 Authors: Volpicelli LA; Levey AI -
Functional screening of drug target genes: m1 muscarinic acetylcholine receptor phenotypes in degenerative dementias.
Am J Pharmacogenomics Volume: 4 Page(s): 119 - 128
01/01/2004 Authors: Weiner DM; Goodman MW; Colpitts TM; Feddock MA; Duggento KL; Nash NR; Levey AI; Brann MR -
Differential subcellular and subsynaptic distribution of GABA(A) and GABA(B) receptors in the monkey subthalamic nucleus.
Neuroscience Volume: 127 Page(s): 709 - 721
01/01/2004 Authors: Galvan A; Charara A; Pare J-F; Levey AI; Smith Y -
Altered striatal function and muscarinic cholinergic receptors in acetylcholinesterase knockout mice.
Mol Pharmacol Volume: 64 Page(s): 1309 - 1316
12/01/2003 Authors: Volpicelli-Daley LA; Hrabovska A; Duysen EG; Ferguson SM; Blakely RD; Lockridge O; Levey AI -
Vesicular localization and activity-dependent trafficking of presynaptic choline transporters.
J Neurosci Volume: 23 Page(s): 9697 - 9709
10/29/2003 Authors: Ferguson SM; Savchenko V; Apparsundaram S; Zwick M; Wright J; Heilman CJ; Yi H; Levey AI; Blakely RD -
Destruction of midbrain dopaminergic neurons by using immunotoxin to dopamine transporter.
Cell Mol Neurobiol Volume: 23 Page(s): 839 - 850
10/01/2003 Authors: Wiley RG; Harrison MB; Levey AI; Lappi DA -
Munc18 interacting proteins: ADP-ribosylation factor-dependent coat proteins that regulate the traffic of beta-Alzheimer's precursor protein.
J Biol Chem Volume: 278 Page(s): 36032 - 36040
09/19/2003 Authors: Hill K; Li Y; Bennett M; McKay M; Zhu X; Shern J; Torre E; Lah JJ; Levey AI; Kahn RA -
Distribution of high affinity choline transporter immunoreactivity in the primate central nervous system.
J Comp Neurol Volume: 463 Page(s): 341 - 357
08/25/2003 Authors: Kus L; Borys E; Ping Chu Y; Ferguson SM; Blakely RD; Emborg ME; Kordower JH; Levey AI; Mufson EJ -
Chronically mad as a hatter: anticholinergics and Alzheimer's disease pathology.
Ann Neurol Volume: 54 Page(s): 144 - 146
08/01/2003 Authors: Levey AI -
Complexes of HLA-G protein on the cell surface are important for leukocyte Ig-like receptor-1 function.
J Immunol Volume: 171 Page(s): 1343 - 1351
08/01/2003 Authors: Gonen-Gross T; Achdout H; Gazit R; Hanna J; Mizrahi S; Markel G; Goldman-Wohl D; Yagel S; Horejs V; Levy O -
Altered hippocampal muscarinic receptors in acetylcholinesterase-deficient mice.
Ann Neurol Volume: 53 Page(s): 788 - 796
06/01/2003 Authors: Volpicelli-Daley LA; Duysen EG; Lockridge O; Levey AI -
Regulation of muscarinic acetylcholine receptor function in acetylcholinesterase knockout mice.
Pharmacol Biochem Behav Volume: 74 Page(s): 977 - 986
03/01/2003 Authors: Li B; Duysen EG; Volpicelli-Daley LA; Levey AI; Lockridge O -
Interaction of isoflurane with the dopamine transporter.
Anesthesiology Volume: 98 Page(s): 404 - 411
02/01/2003 Authors: Votaw J; Byas-Smith M; Hua J; Voll R; Martarello L; Levey AI; Bowman FD; Goodman M -
Phenylephrine and norepinephrine increase dopamine transporter ligand binding in striatum.
Mol Imaging Biol Volume: 5 Page(s): 217 - 226
01/01/2003 Authors: Byas-Smith M; Votaw J; Hua J; Voll R; Martarello L; Levey AI; Goodman M -
Cell-specific extracellular signal-regulated kinase activation by multiple G protein-coupled receptor families in hippocampus.
Mol Pharmacol Volume: 63 Page(s): 128 - 135
01/01/2003 Authors: Berkeley JL; Levey AI -
Rab11a and myosin Vb regulate recycling of the M4 muscarinic acetylcholine receptor.
J Neurosci Volume: 22 Page(s): 9776 - 9784
11/15/2002 Authors: Volpicelli LA; Lah JJ; Fang G; Goldenring JR; Levey AI -
Zinc transporter 3 (ZnT3) defines a distinct synaptic vesicles subpopulation
Volume: 13 Page(s): 396A - 396A
11/01/2002 Authors: Salazar G; Love R; Werner E; Cheng S; Levey A; Faundez V -
Evaluation of muscarinic agonist-induced analgesia in muscarinic acetylcholine receptor knockout mice.
Mol Pharmacol Volume: 62 Page(s): 1084 - 1093
11/01/2002 Authors: Duttaroy A; Gomeza J; Gan J-W; Siddiqui N; Basile AS; Harman WD; Smith PL; Felder CC; Levey AI; Wess J -
Acute mitochondrial and chronic toxicological effects of 1-methyl-4-phenylpyridinium in human neuroblastoma cells.
Neurotoxicology Volume: 23 Page(s): 569 - 580
10/01/2002 Authors: Stephans SE; Miller GW; Levey AI; Greenamyre JT -
Role of presynaptic muscarinic and GABA(B) receptors in spinal glutamate release and cholinergic analgesia in rats.
J Physiol Volume: 543 Page(s): 807 - 818
09/15/2002 Authors: Li D-P; Chen S-R; Pan Y-Z; Levey AI; Pan H-L -
Novel interaction between the M4 muscarinic acetylcholine receptor and elongation factor 1A2.
J Biol Chem Volume: 277 Page(s): 29268 - 29274
08/09/2002 Authors: McClatchy DB; Knudsen CR; Clark BF; Kahn RA; Hall RA; Levey AI -
Huntingtin-associated protein 1 interacts with hepatocyte growth factor-regulated tyrosine kinase substrate and functions in endosomal trafficking.
J Biol Chem Volume: 277 Page(s): 28212 - 28221
08/02/2002 Authors: Li Y; Chin L-S; Levey AI; Li L -
Complex relationship between Parkin mutations and Parkinson disease.
Am J Med Genet Volume: 114 Page(s): 584 - 591
07/08/2002 Authors: West A; Periquet M; Lincoln S; Lcking CB; Nicholl D; Bonifati V; Rawal N; Gasser T; Lohmann E; Deleuze J-F -
The role of muscarinic acetylcholine receptor-mediated activation of extracellular signal-regulated kinase 1/2 in pilocarpine-induced seizures.
J Neurochem Volume: 82 Page(s): 192 - 201
07/01/2002 Authors: Berkeley JL; Decker MJ; Levey AI -
BACE activity is regulated by an internal loop region whose sequence resembles the beta-secretase cleavage site of the amyloid precursor protein
NEUROBIOLOGY OF AGING Volume: 23 Page(s): S182 - S183
07/01/2002 Authors: McGraw W; Lah J; Levey A -
The effects of AC-90222, a selective m1 agonist with low affinity D2 antagonism in cognitive and antipsychotic behavioral assays
NEUROBIOLOGY OF AGING Volume: 23 Page(s): S112 - S112
07/01/2002 Authors: Veinbergs I; Schurb KL; Friberg M; Rodriguez MA; Wu W; Spalding TA; Skjaerbaek N; Tolf BR; Hacksell U; Brann MR -
Snoring and cognitive impairment in a memory clinic population
SLEEP Volume: 25 Page(s): A6 - A6
04/15/2002 Authors: Bliwise DL; Straight LB; Ansari FP; Levey AI -
Very early activation of m-calpain in peripheral nerve during Wallerian degeneration.
J Neurol Sci Volume: 196 Page(s): 9 - 20
04/15/2002 Authors: Glass JD; Culver DG; Levey AI; Nash NR -
Refractory nonmotor symptoms in male Parkinson patients due to testosterone deficiency: A common unrecognized comorbidity
Volume: 58 Page(s): A284 - A284
04/09/2002 Authors: Okun MS; McDonald WM; Hanfelt J; Green J; Levey A; Ciliax B; Gearing M; Vitek JL; DeLong MR -
Effects of manipulating endosomal traffic on amyloid precursor protein metabolism and amyloid beta peptide secretion
NEUROLOGY Volume: 58 Page(s): A362 - A362
04/09/2002 Authors: Lah JJ; Levey AI -
Role of presynaptic muscarinic and GABA(B) receptors in spinal glutamate release and cholinergic analgesia
FASEB JOURNAL Volume: 16 Page(s): A105 - A105
03/20/2002 Authors: Li DP; Chen SR; Pan YZ; Levey AI; Pan HL -
Characterization of central inhibitory muscarinic autoreceptors by the use of muscarinic acetylcholine receptor knock-out mice.
J Neurosci Volume: 22 Page(s): 1709 - 1717
03/01/2002 Authors: Zhang W; Basile AS; Gomeza J; Volpicelli LA; Levey AI; Wess J -
Loss of basal forebrain P75(NTR) immunoreactivity in subjects with mild cognitive impairment and Alzheimer's disease.
J Comp Neurol Volume: 443 Page(s): 136 - 153
02/04/2002 Authors: Mufson EJ; Ma SY; Dills J; Cochran EJ; Leurgans S; Wuu J; Bennett DA; Jaffar S; Gilmor ML; Levey AI -
Acetylcholinesterase knockouts establish central cholinergic pathways and can use butyrylcholinesterase to hydrolyze acetylcholine.
Neuroscience Volume: 110 Page(s): 627 - 639
01/01/2002 Authors: Mesulam M-M; Guillozet A; Shaw P; Levey A; Duysen EG; Lockridge O -
Notch signaling inhibits PC12 cell neurite outgrowth via RBP-J-dependent and -independent mechanisms.
Dev Neurosci Volume: 24 Page(s): 79 - 88
01/01/2002 Authors: Levy OA; Lah JJ; Levey AI -
Presenilin 1 independently regulates beta-catenin stability and transcriptional activity.
J Biol Chem Volume: 276 Page(s): 48554 - 48561
12/21/2001 Authors: Killick R; Pollard CC; Asuni AA; Mudher AK; Richardson JC; Rupniak HT; Sheppard PW; Varndell IM; Brion JP; Levey AI -
Rab5-dependent trafficking of the m4 muscarinic acetylcholine receptor to the plasma membrane, early endosomes, and multivesicular bodies.
J Biol Chem Volume: 276 Page(s): 47590 - 47598
12/14/2001 Authors: Volpicelli LA; Lah JJ; Levey AI -
Muscarinic receptor M(2) in cat visual cortex: laminar distribution, relationship to gamma-aminobutyric acidergic neurons, and effect of cingulate lesions.
J Comp Neurol Volume: 441 Page(s): 168 - 185
12/10/2001 Authors: Erisir A; Levey AI; Aoki C -
Localization of the AMPA subunit GluR2 in the outer plexiform layer of goldfish retina.
J Comp Neurol Volume: 441 Page(s): 155 - 167
12/10/2001 Authors: Klooster J; Studholme KM; Yazulla S -
Apolipoprotein E and age at onset of Alzheimer's disease in African American patients.
Neurology Volume: 57 Page(s): 1923 - 1925
11/27/2001 Authors: Goldstein FC; Ashley AV; Gearing M; Hanfelt J; Penix L; Freedman LJ; Levey AI -
Multiple effects of aspartate mutant presenilin 1 on the processing and trafficking of amyloid precursor protein.
J Biol Chem Volume: 276 Page(s): 43343 - 43350
11/16/2001 Authors: Kim SH; Leem JY; Lah JJ; Slunt HH; Levey AI; Thinakaran G; Sisodia SS -
M1 muscarinic acetylcholine receptors activate extracellular signal-regulated kinase in CA1 pyramidal neurons in mouse hippocampal slices.
Mol Cell Neurosci Volume: 18 Page(s): 512 - 524
11/01/2001 Authors: Berkeley JL; Gomeza J; Wess J; Hamilton SE; Nathanson NM; Levey AI -
Nigrostriatal collaterals to thalamus degenerate in parkinsonian animal models.
Ann Neurol Volume: 50 Page(s): 321 - 329
09/01/2001 Authors: Freeman A; Ciliax B; Bakay R; Daley J; Miller RD; Keating G; Levey A; Rye D -
Ionotropic and metabotropic GABA and glutamate receptors in primate basal ganglia.
J Chem Neuroanat Volume: 22 Page(s): 13 - 42
07/01/2001 Authors: Smith Y; Charara A; Paquet M; Kieval JZ; Par JF; Hanson JE; Hubert GW; Kuwajima M; Levey AI -
Muscarinic m1 and m2 receptor proteins in local circuit and projection neurons of the primate striatum: anatomical evidence for cholinergic modulation of glutamatergic prefronto-striatal pathways.
J Comp Neurol Volume: 434 Page(s): 445 - 460
06/11/2001 Authors: Alcantara AA; Mrzljak L; Jakab RL; Levey AI; Hersch SM; Goldman-Rakic PS -
M1 muscarinic acetylcholine receptors activate MAPK in brain
LIFE SCIENCES Volume: 68 Page(s): 2624 - 2624
04/27/2001 Authors: Berkeley JL; Hamilton SE; Nathanson NM; Wess J; Levey AI -
Expression of muscarinic receptors positively coupled to cyclic amp in the different layers of rat main olfactory bulb.
LIFE SCIENCES Volume: 68 Page(s): 2615 - 2615
04/27/2001 Authors: Olianas MC; Rouse ST; Levey AI; Onali P -
Evaluation of muscarinic agonist-induced analgesia in muscarinic receptor knockout mice
LIFE SCIENCES Volume: 68 Page(s): 2631 - 2631
04/27/2001 Authors: Duttaroy A; Gomeza J; Gan JW; Basile AS; Harman WD; Smith PL; Felder CC; Levey AI; Wess J -
Muscarinic M4 acetylcholine receptor interacts with elongation factor 1A2 (EEF1A2).
LIFE SCIENCES Volume: 68 Page(s): 2642 - 2642
04/27/2001 Authors: McClatchy DB; Hall RA; Levey AI -
M1 and M4 subtypes of muscarinic receptors traffic through distinct endosomal compartments in PC12 cells
LIFE SCIENCES Volume: 68 Page(s): 2623 - 2623
04/27/2001 Authors: Volpicelli LA; Lah JJ; Levey AI -
Apolipoprotein E and age of onset of Alzheimer's disease in African American patients
Volume: 56 Page(s): A113 - A114
04/24/2001 Authors: Goldstein FC; Ashley AV; Gearing M; Hanfelt J; Penix L; Freedman L; Levey AI -
Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1.
Neuron Volume: 30 Page(s): 121 - 134
04/01/2001 Authors: Torres GE; Yao WD; Mohn AR; Quan H; Kim KM; Levey AI; Staudinger J; Caron MG -
The regulation of presenilin-1 by nerve growth factor.
J Neurochem Volume: 76 Page(s): 679 - 689
02/01/2001 Authors: Counts SE; Lah JJ; Levey AI -
Immunochemical analysis of dopamine transporters in Parkinson's disease.
Methods Mol Med Volume: 62 Page(s): 167 - 177
01/01/2001 Authors: Miller GW; Levey AI -
Phenotypic differences in cholinergic markers within the nucleus basalis in individuals with mild cognitive impairment
Page(s): 253 - 264
01/01/2001 Authors: Mufson EJ; Gilmor M; Ma SY; Levey AI; Kordower JH -
Functional downregulation of GluR2 in piriform cortex of kindled animals.
Synapse Volume: 38 Page(s): 489 - 498
12/15/2000 Authors: Prince HC; Tzingounis AV; Levey AI; Conn PJ -
Activation of metabotropic glutamate receptor 5 has direct excitatory effects and potentiates NMDA receptor currents in neurons of the subthalamic nucleus.
J Neurosci Volume: 20 Page(s): 7871 - 7879
11/01/2000 Authors: Awad H; Hubert GW; Smith Y; Levey AI; Conn PJ -
Immunization for Alzheimer's disease: a shot in the arm or a whiff?
Ann Neurol Volume: 48 Page(s): 553 - 555
10/01/2000 Authors: Levey AI -
Cortical inputs to m2-immunoreactive striatal interneurons in rat and monkey.
Synapse Volume: 37 Page(s): 252 - 261
09/15/2000 Authors: Thomas TM; Smith Y; Levey AI; Hersch SM -
Large-scale gene expression in Alzheimer's disease lymphoblasts
ANNALS OF NEUROLOGY Volume: 48 Page(s): 429 - 429
09/01/2000 Authors: Scherzer CR; Lah J; Bennett-Desmelik JA; Fang G; Counts S; Greenamyre JT; Levey AI -
Dopamine D(5) receptor immunolocalization in rat and monkey brain.
Synapse Volume: 37 Page(s): 125 - 145
08/01/2000 Authors: Ciliax BJ; Nash N; Heilman C; Sunahara R; Hartney A; Tiberi M; Rye DB; Caron MG; Niznik HB; Levey AI -
Endogenous presenilin-1 targets to endocytic rather than biosynthetic compartments.
Mol Cell Neurosci Volume: 16 Page(s): 111 - 126
08/01/2000 Authors: Lah JJ; Levey AI -
Muscarinic activation of mitogen-activated protein kinase in PC12 cells.
J Neurochem Volume: 75 Page(s): 487 - 493
08/01/2000 Authors: Berkeley JL; Levey AI -
Phosphorylation of the rat vesicular acetylcholine transporter.
J Biol Chem Volume: 275 Page(s): 19942 - 19948
06/30/2000 Authors: Cho GW; Kim MH; Chai YG; Gilmor ML; Levey AI; Hersh LB -
Activation of group II metabotropic glutamate receptors inhibits synaptic excitation of the substantia Nigra pars reticulata.
J Neurosci Volume: 20 Page(s): 3085 - 3094
05/01/2000 Authors: Bradley SR; Marino MJ; Wittmann M; Rouse ST; Awad H; Levey AI; Conn PJ -
GABA(B) and group I metabotropic glutamate receptors in the striatopallidal complex in primates.
J Anat Volume: 196 ( Pt 4) Page(s): 555 - 576
05/01/2000 Authors: Smith Y; Charara A; Hanson JE; Paquet M; Levey AI -
Localization of M(2) muscarinic acetylcholine receptor protein in cholinergic and non-cholinergic terminals in rat hippocampus.
Neurosci Lett Volume: 284 Page(s): 182 - 186
04/28/2000 Authors: Rouse ST; Edmunds SM; Yi H; Gilmor ML; Levey AI -
Subcellular localization of presenilins: association with a unique membrane pool in cultured cells.
Neurobiol Dis Volume: 7 Page(s): 99 - 117
04/01/2000 Authors: Kim SH; Lah JJ; Thinakaran G; Levey A; Sisodia SS -
Anatomical and physiological evidence for D1 and D2 dopamine receptor colocalization in neostriatal neurons.
Nat Neurosci Volume: 3 Page(s): 226 - 230
03/01/2000 Authors: Aizman O; Brismar H; Uhln P; Zettergren E; Levey AI; Forssberg H; Greengard P; Aperia A -
Molecules of the brain.
Hosp Pract (1995) Volume: 35 Page(s): 41 - 54
02/15/2000 Authors: Levey AI -
LIM kinase 1 accumulates in presynaptic terminals during synapse maturation.
J Comp Neurol Volume: 416 Page(s): 319 - 334
01/17/2000 Authors: Wang JY; Wigston DJ; Rees HD; Levey AI; Falls DL -
Pre- and postsynaptic localization of GABA(B) receptors in the basal ganglia in monkeys.
Neuroscience Volume: 95 Page(s): 127 - 140
01/01/2000 Authors: Charara A; Heilman TC; Levey AI; Smith Y -
Levodopa induces a cytoplasmic localization of D1 dopamine receptors in striatal neurons in Parkinson's disease - Reply
ANNALS OF NEUROLOGY Volume: 47 Page(s): 137 - 137
01/01/2000 Authors: Muriel MP; Bernard V; Levey AI; Laribi O; Abrous DN; Agid Y; Bloch B; Hirsch EC -
Localization of metabotropic glutamate receptor 7 mRNA and mGluR7a protein in the rat basal ganglia.
J Comp Neurol Volume: 415 Page(s): 266 - 284
12/13/1999 Authors: Kosinski CM; Risso Bradley S; Conn PJ; Levey AI; Landwehrmeyer GB; Penney JB; Young AB; Standaert DG -
Regulation of the subcellular distribution of m4 muscarinic acetylcholine receptors in striatal neurons in vivo by the cholinergic environment: evidence for regulation of cell surface receptors by endogenous and exogenous stimulation.
J Neurosci Volume: 19 Page(s): 10237 - 10249
12/01/1999 Authors: Bernard V; Levey AI; Bloch B -
Event-related potential changes in groups at increased risk for Alzheimer disease.
Arch Neurol Volume: 56 Page(s): 1398 - 1403
11/01/1999 Authors: Green J; Levey AI -
LIM Kinase 1 is concentrated in adult presynaptic terminals.
MOLECULAR BIOLOGY OF THE CELL Volume: 10 Page(s): 231A - 231A
11/01/1999 Authors: Falls DL; Wang JY; Wigston DJ; Rees HD; Levey AI -
Dopamine transporters and neuronal injury.
Trends Pharmacol Sci Volume: 20 Page(s): 424 - 429
10/01/1999 Authors: Miller GW; Gainetdinov RR; Levey AI; Caron MG -
Potential antiparkinsonian actions on metabotropic glutamate receptors in the substantia nigra pars reticulate
NEUROPHARMACOLOGY Volume: 38 Page(s): A29 - A29
10/01/1999 Authors: Marino MJ; Bradley SR; Wittmann M; Rouse ST; Levey AI; Conn PJ -
(2S, 1 ' S, 2 ' S, 3 ' R)-2-(2 '-carboxy-3 '-(3,3-diphenylpropy cyclopropylclycine (UPF 665): A new selective mGluR2 antagonist: Synthesis, preliminary evaluation and molecular modeling studies
Volume: 38 Page(s): A29 - A30
10/01/1999 Authors: Marinozzi M; Amori L; Pellicciari R; Costantino G -
Preservation of nucleus basalis neurons containing choline acetyltransferase and the vesicular acetylcholine transporter in the elderly with mild cognitive impairment and early Alzheimer's disease.
J Comp Neurol Volume: 411 Page(s): 693 - 704
09/06/1999 Authors: Gilmor ML; Erickson JD; Varoqui H; Hersh LB; Bennett DA; Cochran EJ; Mufson EJ; Levey AI -
Heptachlor alters expression and function of dopamine transporters.
Neurotoxicology Volume: 20 Page(s): 631 - 637
08/01/1999 Authors: Miller GW; Kirby ML; Levey AI; Bloomquist JR -
Levodopa induces a cytoplasmic localization of D1 dopamine receptors in striatal neurons in Parkinson's disease.
Ann Neurol Volume: 46 Page(s): 103 - 111
07/01/1999 Authors: Muriel MP; Bernard V; Levey AI; Laribi O; Abrous DN; Agid Y; Bloch B; Hirsch EC -
Immunocytochemical localization of the dopamine transporter in human brain.
J Comp Neurol Volume: 409 Page(s): 38 - 56
06/21/1999 Authors: Ciliax BJ; Drash GW; Staley JK; Haber S; Mobley CJ; Miller GW; Mufson EJ; Mash DC; Levey AI -
Dopamine transporter-immunoreactive neurons decrease with age in the human substantia nigra.
J Comp Neurol Volume: 409 Page(s): 25 - 37
06/21/1999 Authors: Ma SY; Ciliax BJ; Stebbins G; Jaffar S; Joyce JN; Cochran EJ; Kordower JH; Mash DC; Levey AI; Mufson EJ -
Distribution of group III mGluRs in rat basal ganglia with subtype-specific antibodies.
Ann N Y Acad Sci Volume: 868 Page(s): 531 - 534
04/30/1999 Authors: Bradley SR; Standaert DG; Levey AI; Conn PJ -
Immunohistochemical localization of subtype 4a metabotropic glutamate receptors in the rat and mouse basal ganglia.
J Comp Neurol Volume: 407 Page(s): 33 - 46
04/28/1999 Authors: Bradley SR; Standaert DG; Rhodes KJ; Rees HD; Testa CM; Levey AI; Conn PJ -
Noncompetitive AMPA glutamate receptor antagonist (LY300164) potentiates the behavioral effects of levodopa in hemiparkinsonian monkeys
NEUROLOGY Volume: 52 Page(s): A216 - A216
04/01/1999 Authors: Subramanian T; Levey AI; Hubert GW; Miller GW; Schoepp DD; Watts RL -
Cholinergic and galaninergic basal forebrain correlates of mild cognitive impairment in Alzheimer's disease
NEUROLOGY Volume: 52 Page(s): A563 - A563
04/01/1999 Authors: Mufson EJ; Gilmore ML; Cochran EJ; Bennett D; Kordower JH; Levey AI -
Tau pathology in a family with dementia and a P301L mutation in tau.
J Neuropathol Exp Neurol Volume: 58 Page(s): 335 - 345
04/01/1999 Authors: Mirra SS; Murrell JR; Gearing M; Spillantini MG; Goedert M; Crowther RA; Levey AI; Jones R; Green J; Shoffner JM -
Clinico-pathological findings following intraventricular GDNF treatment in a patient with Parkinson's disease
NEUROLOGY Volume: 52 Page(s): A4 - A5
04/01/1999 Authors: Kordower JH; Palfi S; Mufson EJ; Levey AI; Chen EY; Ma S; Cochran EJ; Penn RD; Gash DM; Comella CL -
Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease.
Exp Neurol Volume: 156 Page(s): 138 - 148
03/01/1999 Authors: Miller GW; Erickson JD; Perez JT; Penland SN; Mash DC; Rye DB; Levey AI -
m2 muscarinic receptor immunolocalization in cholinergic cells of the monkey basal forebrain and striatum.
Neuroscience Volume: 90 Page(s): 803 - 814
03/01/1999 Authors: Smiley JF; Levey AI; Mesulam MM -
On the distribution patterns of D1, D2, tyrosine hydroxylase and dopamine transporter immunoreactivities in the ventral striatum of the rat.
Neuroscience Volume: 89 Page(s): 473 - 489
03/01/1999 Authors: Jansson A; Goldstein M; Tinner B; Zoli M; Meador-Woodruff JH; Lew JY; Levey AI; Watson S; Agnati LF; Fuxe K -
Muscarinic receptor subtypes in the lateral geniculate nucleus: a light and electron microscopic analysis.
J Comp Neurol Volume: 404 Page(s): 408 - 425
02/15/1999 Authors: Plummer KL; Manning KA; Levey AI; Rees HD; Uhlrich DJ -
Muscarinic activation of MAPK in PC12 cells
LIFE SCIENCES Volume: 64 Page(s): 566 - 566
01/08/1999 Authors: Berkeley JL; Lah JJ; Levey AI -
Muscarinic receptors in the superficial dorsal horn of the human, rat, and mouse spinal cord.
LIFE SCIENCES Volume: 64 Page(s): 585 - 585
01/08/1999 Authors: Potter LT; Borenstein MT; Levey AI -
Muscarinic receptor subtypes involved in hippocampal circuits.
Life Sci Volume: 64 Page(s): 501 - 509
01/01/1999 Authors: Rouse ST; Marino MJ; Potter LT; Conn PJ; Levey AI -
Differential effects of transforming growth factor-beta(s) and glial cell line-derived neurotrophic factor on gene expression of presenilin-1 in human post-mitotic neurons and astrocytes.
Neuroscience Volume: 93 Page(s): 1041 - 1049
01/01/1999 Authors: Ren RF; Lah JJ; Diehlmann A; Kim ES; Hawver DB; Levey AI; Beyreuther K; Flanders KC -
Rat dorsal root ganglia express m1-m4 muscarinic receptor proteins.
J Peripher Nerv Syst Volume: 4 Page(s): 222 - 232
01/01/1999 Authors: Bernardini N; Levey AI; Augusti-Tocco G -
Subcellular redistribution of m2 muscarinic acetylcholine receptors in striatal interneurons in vivo after acute cholinergic stimulation.
J Neurosci Volume: 18 Page(s): 10207 - 10218
12/01/1998 Authors: Bernard V; Laribi O; Levey AI; Bloch B -
Coordinate expression of the vesicular acetylcholine transporter and choline acetyltransferase following septohippocampal pathway lesions.
J Neurochem Volume: 71 Page(s): 2411 - 2420
12/01/1998 Authors: Gilmor ML; Counts SE; Wiley RG; Levey AI -
Age-related declines in nigral neuronal function correlate with motor impairments in rhesus monkeys.
J Comp Neurol Volume: 401 Page(s): 253 - 265
11/16/1998 Authors: Emborg ME; Ma SY; Mufson EJ; Levey AI; Taylor MD; Brown WD; Holden JE; Kordower JH -
Infracortical interstitial cells concurrently expressing m2-muscarinic receptors, acetylcholinesterase and nicotinamide adenine dinucleotide phosphate-diaphorase in the human and monkey cerebral cortex. (vol 84, pg 755, 1998)
NEUROSCIENCE Volume: 87 Page(s): 317 - 318
11/01/1998 Authors: Smiley JF; Levey AI; Mesulam MM -
Nigrostriatal degeneration and impaired motor function in aged rhesus monkeys: A model of human aging and early Parkinson's disease (PD) for neural transplantation
EXPERIMENTAL NEUROLOGY Volume: 153 Page(s): 389 - 389
10/01/1998 Authors: Emborg ME; Ma SY; Mufson EJ; Levey A; Holden JE; Brown D; Kordower JH -
Activation of the genetically defined m1 muscarinic receptor potentiates N-methyl-D-aspartate (NMDA) receptor currents in hippocampal pyramidal cells.
Proc Natl Acad Sci U S A Volume: 95 Page(s): 11465 - 11470
09/15/1998 Authors: Marino MJ; Rouse ST; Levey AI; Potter LT; Conn PJ -
Differential presynaptic and postsynaptic expression of m1-m4 muscarinic acetylcholine receptors at the perforant pathway/granule cell synapse.
Neuroscience Volume: 86 Page(s): 221 - 232
09/01/1998 Authors: Rouse ST; Gilmor ML; Levey AI -
Inefficient processing of Alzheimer's disease-associated mutant presenilin-1 in primary hippocampal neurons
ANNALS OF NEUROLOGY Volume: 44 Page(s): 446 - 446
09/01/1998 Authors: Weihl CC; Ghadge GD; Miller RJ; Sisodia SS; Levey AI; Roos RP -
Rapid changes in m-calpain after axotomy but before wallerian degeneration
ANNALS OF NEUROLOGY Volume: 44 Page(s): 462 - 462
09/01/1998 Authors: Glass JD; Culver DG; Levey AI; Nash N -
Evidence for the presence of muscarinic M2 and M4 receptors in guinea-pig gallbladder smooth muscle.
J Auton Pharmacol Volume: 18 Page(s): 195 - 204
08/01/1998 Authors: Oktay S; Cabadak H; Iskender E; Gren Z; Calikan E; Orun O; Aslan N; Karaalp A; Tolun A; Ulusoy NB -
Distribution and developmental regulation of metabotropic glutamate receptor 7a in rat brain.
J Neurochem Volume: 71 Page(s): 636 - 645
08/01/1998 Authors: Bradley SR; Rees HD; Yi H; Levey AI; Conn PJ -
Presenilin-1 expression during rat brain development
BRAIN PATHOLOGY Volume: 8 Page(s): 580 - 580
07/01/1998 Authors: Levy OA; Rees H; Heilman C; Levey AI -
Regulation of presenilin-1 during neuronotypic differentiation of PC12 cells
BRAIN PATHOLOGY Volume: 8 Page(s): 579 - 579
07/01/1998 Authors: Counts SE; Lah JJ; Levey AI -
Cloning of m-calpain 80 kD subunit from the axonal degeneration-resistant WLD(S) mouse mutant.
J Neurosci Res Volume: 52 Page(s): 653 - 660
06/15/1998 Authors: Glass JD; Nash N; Dry I; Culver D; Levey AI; Wesselingh S -
Infracortical interstitial cells concurrently expressing m2-muscarinic receptors, acetylcholinesterase and nicotinamide adenine dinucleotide phosphate-diaphorase in the human and monkey cerebral cortex.
Neuroscience Volume: 84 Page(s): 755 - 769
06/01/1998 Authors: Smiley JF; Levey AI; Mesulam MM -
Increased MPTP neurotoxicity in vesicular monoamine transporter 2 heterozygote knockout mice.
J Neurochem Volume: 70 Page(s): 1973 - 1978
05/01/1998 Authors: Gainetdinov RR; Fumagalli F; Wang YM; Jones SR; Levey AI; Miller GW; Caron MG -
Tau cytopathology in a patient with familial early onset dementia.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 57 Page(s): 509 - 509
05/01/1998 Authors: Gearing M; Levey AI; Jones R; Walton W; Shoffner JM; Schmidt ML; Trojanowski JO; Ghetti B; Mirra SS -
Age related changes in dopamine transporter immunoreactivity within the human substantia nigra: An unbiased stereologic evaluation.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY Volume: 57 Page(s): 510 - 510
05/01/1998 Authors: Mufson EJ; Ma SY; Jaffar S; Ciliax BJ; Joyce J; Cochran E; Mash DC; Kordower JH; Levey AI -
Dopamine axon varicosities in the prelimbic division of the rat prefrontal cortex exhibit sparse immunoreactivity for the dopamine transporter.
J Neurosci Volume: 18 Page(s): 2697 - 2708
04/01/1998 Authors: Sesack SR; Hawrylak VA; Matus C; Guido MA; Levey AI -
m2 muscarinic acetylcholine receptor-immunoreactive neurons are not reduced within the nucleus basalis in Alzheimer's disease: relationship with cholinergic and galaninergic perikarya.
J Comp Neurol Volume: 392 Page(s): 313 - 329
03/16/1998 Authors: Mufson EJ; Jaffar S; Levey AI -
Localization of the m2 muscarinic acetylcholine receptor protein and mRNA in cortical neurons of the normal and cholinergically deafferented rhesus monkey.
J Comp Neurol Volume: 390 Page(s): 112 - 132
01/05/1998 Authors: Mrzljak L; Levey AI; Belcher S; Goldman-Rakic PS -
Generation of transporter-specific antibodies.
Methods Enzymol Volume: 296 Page(s): 407 - 422
01/01/1998 Authors: Miller GW; Gilmor ML; Levey AI -
Postnatal development of tyrosine hydroxylase- and dopamine transporter-immunoreactive axons in monkey rostral entorhinal cortex.
Cereb Cortex Volume: 8 Page(s): 415 - 427
01/01/1998 Authors: Erickson SL; Akil M; Levey AI; Lewis DA -
Distinct interneuron types express m2 muscarinic receptor immunoreactivity on their dendrites or axon terminals in the hippocampus.
Neuroscience Volume: 82 Page(s): 355 - 376
01/01/1998 Authors: Hjos N; Papp EC; Acsdy L; Levey AI; Freund TF -
Cellular and subcellular localization of the dopamine transporter in rat cortex.
Adv Pharmacol Volume: 42 Page(s): 171 - 174
01/01/1998 Authors: Sesack SR; Hawrylak VA; Guido MA; Levey AI -
Dopamine axons in primate prefrontal cortex: specificity of distribution, synaptic targets, and development.
Adv Pharmacol Volume: 42 Page(s): 703 - 706
01/01/1998 Authors: Lewis DA; Sesack SR; Levey AI; Rosenberg DR -
Ultrastructural localization of neurotransmitter receptors and transporters at synapses in the rat central nervous system
Page(s): 935 - 936
01/01/1998 Authors: Yi H; Levey AI; Hersch SM -
Diffuse plaques in the striatum in Alzheimer disease (AD): relationship to the striatal mosaic and selected neuropeptide markers.
J Neuropathol Exp Neurol Volume: 56 Page(s): 1363 - 1370
12/01/1997 Authors: Gearing M; Levey AI; Mirra SS -
Differential expression of D1 and D2 dopamine and m4 muscarinic acetylcholine receptor proteins in identified striatonigral neurons.
Synapse Volume: 27 Page(s): 357 - 366
12/01/1997 Authors: Ince E; Ciliax BJ; Levey AI -
Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice.
Proc Natl Acad Sci U S A Volume: 94 Page(s): 13311 - 13316
11/25/1997 Authors: Hamilton SE; Loose MD; Qi M; Levey AI; Hille B; McKnight GS; Idzerda RL; Nathanson NM -
Subcellular localization and molecular topology of the dopamine transporter in the striatum and substantia nigra.
J Comp Neurol Volume: 388 Page(s): 211 - 227
11/17/1997 Authors: Hersch SM; Yi H; Heilman CJ; Edwards RH; Levey AI -
Distribution of muscarinic cholinergic receptor proteins m1 to m4 in area 17 of normal and monocularly deprived rhesus monkeys.
J Comp Neurol Volume: 388 Page(s): 130 - 145
11/10/1997 Authors: Tigges M; Tigges J; Rees H; Rye D; Levey AI -
Calpains and calpastatin in axonal degeneration
ANNALS OF NEUROLOGY Volume: 42 Page(s): M102 - M102
09/01/1997 Authors: Glass JD; GoodwinCulver D; Castejon S; Nash N; Levey AI; Powers J -
Dopaminergic neurons intrinsic to the primate striatum.
J Neurosci Volume: 17 Page(s): 6761 - 6768
09/01/1997 Authors: Betarbet R; Turner R; Chockkan V; DeLong MR; Allers KA; Walters J; Levey AI; Greenamyre JT -
Destruction of midbrain dopaminergic neurons using intraventricular immunotoxin to the dopamine transporter
ANNALS OF NEUROLOGY Volume: 42 Page(s): T210 - T210
09/01/1997 Authors: Wiley RG; Harrison MB; Levey AI; Lappi DA -
Cloning and localization of exon 5-containing isoforms of the NMDAR1 subunit in human and rat brains.
J Neurochem Volume: 69 Page(s): 485 - 493
08/01/1997 Authors: Nash NR; Heilman CJ; Rees HD; Levey AI -
Hyperaccumulation of FAD-linked presenilin 1 variants in vivo.
Nat Med Volume: 3 Page(s): 756 - 760
07/01/1997 Authors: Lee MK; Borchelt DR; Kim G; Thinakaran G; Slunt HH; Ratovitski T; Martin LJ; Kittur A; Gandy S; Levey AI -
Presenilin-1 protein expression in familial and sporadic Alzheimer's disease.
Ann Neurol Volume: 41 Page(s): 742 - 753
06/01/1997 Authors: Levey AI; Heilman CJ; Lah JJ; Nash NR; Rees HD; Wakai M; Mirra SS; Rye DB; Nochlin D; Bird TD -
Muscarinic acetylcholine receptor immunoreactivity after hippocampal commissural/associational pathway lesions: evidence for multiple presynaptic receptor subtypes.
J Comp Neurol Volume: 380 Page(s): 382 - 394
04/14/1997 Authors: Rouse ST; Levey AI -
Striatal dopamine nerve terminal markers but not nigral cellularity are reduced in spinocerebellar ataxia type 1.
Neurology Volume: 48 Page(s): 1109 - 1111
04/01/1997 Authors: Kish SJ; Guttman M; Robitaille Y; el-Awar M; Chang LJ; Levey AI -
Immunochemical analysis of dopamine transporter protein in Parkinson's disease.
Ann Neurol Volume: 41 Page(s): 530 - 539
04/01/1997 Authors: Miller GW; Staley JK; Heilman CJ; Perez JT; Mash DC; Rye DB; Levey AI -
Effects of xanomeline, a selective muscarinic receptor agonist, on cognitive function and behavioral symptoms in Alzheimer disease.
Arch Neurol Volume: 54 Page(s): 465 - 473
04/01/1997 Authors: Bodick NC; Offen WW; Levey AI; Cutler NR; Gauthier SG; Satlin A; Shannon HE; Tollefson GD; Rasmussen K; Bymaster FP -
Alterations in glutamate transporter protein levels in kindling-induced epilepsy.
J Neurochem Volume: 68 Page(s): 1564 - 1570
04/01/1997 Authors: Miller HP; Levey AI; Rothstein JD; Tzingounis AV; Conn PJ -
Light and electron microscopic localization of presenilin-1 in primate brain.
J Neurosci Volume: 17 Page(s): 1971 - 1980
03/15/1997 Authors: Lah JJ; Heilman CJ; Nash NR; Rees HD; Yi H; Counts SE; Levey AI -
Correlation of in-vivo and in-vitro dopamine transporter function
NEUROLOGY Volume: 48 Page(s): 1118 - 1118
03/01/1997 Authors: Hoffman JM; Shi B; Goodman MM; Subramanian T; Levey AI; Watts RL -
Quantitative immunochemical analysis of striatal dopamine transporter in MPTP-induced hemiparkinsonian monkeys
NEUROLOGY Volume: 48 Page(s): 5127 - 5127
03/01/1997 Authors: Subramanian T; Miller GW; Bakay RAE; Watts RL; Levey AI -
Diversity of mAChR heteroreceptor proteins in multiple hippocampal circuits
LIFE SCIENCES Volume: 60 Page(s): 69 - 69
02/21/1997 Authors: Rouse ST; Levey AI -
Radioligand binding and immunoautoradiographic evidence for a lack of toxicity to dopaminergic nerve terminals in human cocaine overdose victims.
Brain Res Volume: 747 Page(s): 219 - 229
02/07/1997 Authors: Staley JK; Talbot JZ; Ciliax BJ; Miller GW; Levey AI; Kung MP; Kung HF; Mash DC -
Muscarinic acetylcholine receptor subtype, m2: diverse functional implications of differential synaptic localization.
Life Sci Volume: 60 Page(s): 1031 - 1038
01/01/1997 Authors: Rouse ST; Thomas TM; Levey AI -
Cholinergic innervation and receptors in the cerebellum.
Prog Brain Res Volume: 114 Page(s): 67 - 96
01/01/1997 Authors: Jaarsma D; Ruigrok TJ; Caff R; Cozzari C; Levey AI; Mugnaini E; Voogd J -
Polarized expression of the antidepressant-sensitive serotonin transporter in epinephrine-synthesizing chromaffin cells of the rat adrenal gland.
Mol Cell Neurosci Volume: 9 Page(s): 170 - 184
01/01/1997 Authors: Schroeter S; Levey AI; Blakely RD -
Polymer-encapsulated PC-12 cells demonstrate high-affinity uptake of dopamine in vitro and 18F-Dopa uptake and metabolism after intracerebral implantation in nonhuman primates.
Cell Transplant Volume: 6 Page(s): 469 - 477
01/01/1997 Authors: Subramanian T; Emerich DF; Bakay RA; Hoffman JM; Goodman MM; Shoup TM; Miller GW; Levey AI; Hubert GW; Batchelor S -
Metabolism of presenilin 1 in transgenic mice
Page(s): 617 - 622
01/01/1997 Authors: Borchelt DR; Lee MK; Thinakaran G; Wong PC; Slunt HH; Ratovitski T; Kim G; Gandy SE; Levey AI; Seeger M -
Cultures of airway parasympathetic nerves express functional M2 muscarinic receptors.
Am J Respir Cell Mol Biol Volume: 15 Page(s): 716 - 725
12/01/1996 Authors: Fryer AD; Elbon CL; Kim AL; Xiao HQ; Levey AI; Jacoby DB -
Expression and endoproteolytic processing of wild type and FAD-linked mutant presenilin 1 in transgenic mice
MOLECULAR BIOLOGY OF THE CELL Volume: 7 Page(s): 3797 - 3797
12/01/1996 Authors: Lee MK; Borchelt D; Thinakaran G; Slunt H; Kim G; Ratoviski T; Martin L; Gandy S; Levey A; Jenkins N -
Muscarinic acetylcholine receptor expression in memory circuits: implications for treatment of Alzheimer disease.
Proc Natl Acad Sci U S A Volume: 93 Page(s): 13541 - 13546
11/26/1996 Authors: Levey AI -
Expression of m1-m4 muscarinic acetylcholine receptor immunoreactivity in septohippocampal neurons and other identified hippocampal afferents.
J Comp Neurol Volume: 375 Page(s): 406 - 416
11/18/1996 Authors: Rouse ST; Levey AI -
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo.
Neuron Volume: 17 Page(s): 1005 - 1013
11/01/1996 Authors: Borchelt DR; Thinakaran G; Eckman CB; Lee MK; Davenport F; Ratovitsky T; Prada CM; Kim G; Seekins S; Yager D -
Immunolocalization of muscarinic acetylcholine subtype 2 receptors in rat cochlear nucleus.
J Comp Neurol Volume: 373 Page(s): 27 - 40
09/09/1996 Authors: Yao W; Godfrey DA; Levey AI -
Differential changes in neurochemical markers of striatal dopamine nerve terminals in idiopathic Parkinson's disease.
Neurology Volume: 47 Page(s): 718 - 726
09/01/1996 Authors: Wilson JM; Levey AI; Rajput A; Ang L; Guttman M; Shannak K; Niznik HB; Hornykiewicz O; Pifl C; Kish SJ -
Striatal dopamine, dopamine transporter, and vesicular monoamine transporter in chronic cocaine users.
Ann Neurol Volume: 40 Page(s): 428 - 439
09/01/1996 Authors: Wilson JM; Levey AI; Bergeron C; Kalasinsky K; Ang L; Peretti F; Adams VI; Smialek J; Anderson WR; Shannak K -
The dopamine transporter carboxyl-terminal tail. Truncation/substitution mutants selectively confer high affinity dopamine uptake while attenuating recognition of the ligand binding domain.
J Biol Chem Volume: 271 Page(s): 20885 - 20894
08/23/1996 Authors: Lee FJ; Pristupa ZB; Ciliax BJ; Levey AI; Niznik HB -
Cell-specific sorting of biogenic amine transporters expressed in epithelial cells.
J Biol Chem Volume: 271 Page(s): 18100 - 18106
07/26/1996 Authors: Gu HH; Ahn J; Caplan MJ; Blakely RD; Levey AI; Rudnick G -
Selective expression of m2 muscarinic receptor in the parvocellular channel of the primate visual cortex.
Proc Natl Acad Sci U S A Volume: 93 Page(s): 7337 - 7340
07/09/1996 Authors: Mrzljak L; Levey AI; Rakic P -
Molecular and functional identification of m1 muscarinic acetylcholine receptors in rat ventricular myocytes.
Circ Res Volume: 79 Page(s): 86 - 93
07/01/1996 Authors: Sharma VK; Colecraft HM; Wang DX; Levey AI; Grigorenko EV; Yeh HH; Sheu SS -
Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo.
Neuron Volume: 17 Page(s): 181 - 190
07/01/1996 Authors: Thinakaran G; Borchelt DR; Lee MK; Slunt HH; Spitzer L; Kim G; Ratovitsky T; Davenport F; Nordstedt C; Seeger M -
Functional fetal nigral grafts in a patient with Parkinson's disease: chemoanatomic, ultrastructural, and metabolic studies.
J Comp Neurol Volume: 370 Page(s): 203 - 230
06/24/1996 Authors: Kordower JH; Rosenstein JM; Collier TJ; Burke MA; Chen EY; Li JM; Martel L; Levey AE; Mufson EJ; Freeman TB -
Striatal dopamine nerve terminal markers in human, chronic methamphetamine users.
Nat Med Volume: 2 Page(s): 699 - 703
06/01/1996 Authors: Wilson JM; Kalasinsky KS; Levey AI; Bergeron C; Reiber G; Anthony RM; Schmunk GA; Shannak K; Haycock JW; Kish SJ -
Synaptic connections between spiny neurons of the direct and indirect pathways in the neostriatum of the rat: evidence from dopamine receptor and neuropeptide immunostaining.
Eur J Neurosci Volume: 8 Page(s): 861 - 869
05/01/1996 Authors: Yung KK; Smith AD; Levey AI; Bolam JP -
Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles.
J Neurosci Volume: 16 Page(s): 2179 - 2190
04/01/1996 Authors: Gilmor ML; Nash NR; Roghani A; Edwards RH; Yi H; Hersch SM; Levey AI -
Immunocytochemical localization of group III metabotropic glutamate receptors in the hippocampus with subtype-specific antibodies.
J Neurosci Volume: 16 Page(s): 2044 - 2056
03/15/1996 Authors: Bradley SR; Levey AI; Hersch SM; Conn PJ -
Light-microscopic distribution and parasagittal organisation of muscarinic receptors in rabbit cerebellar cortex.
J Chem Neuroanat Volume: 9 Page(s): 241 - 259
12/01/1995 Authors: Jaarsma D; Levey AI; Frostholm A; Rotter A; Voogd J -
Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies.
Proc Natl Acad Sci U S A Volume: 92 Page(s): 8710 - 8714
09/12/1995 Authors: Gutekunst CA; Levey AI; Heilman CJ; Whaley WL; Yi H; Nash NR; Rees HD; Madden JJ; Hersch SM -
IDENTIFICATION OF THE HUNTINGTONS-DISEASE PROTEIN IN RAT, MONKEY, AND HUMAN USING ANTIFUSION PROTEIN ANTIBODIES
Volume: 38 Page(s): 298 - 298
08/01/1995 Authors: HERSCH SM; LEVEY AI; GUTEKUNST CA -
Development of muscarinic receptor subtypes in the forebrain of the mouse.
J Comp Neurol Volume: 358 Page(s): 88 - 101
07/17/1995 Authors: Hohmann CF; Potter ED; Levey AI -
Electron microscopic analysis of D1 and D2 dopamine receptor proteins in the dorsal striatum and their synaptic relationships with motor corticostriatal afferents.
J Neurosci Volume: 15 Page(s): 5222 - 5237
07/01/1995 Authors: Hersch SM; Ciliax BJ; Gutekunst CA; Rees HD; Heilman CJ; Yung KK; Bolam JP; Ince E; Yi H; Levey AI -
Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis.
Ann Neurol Volume: 38 Page(s): 73 - 84
07/01/1995 Authors: Rothstein JD; Van Kammen M; Levey AI; Martin LJ; Kuncl RW -
Expression of m1-m4 muscarinic acetylcholine receptor proteins in rat hippocampus and regulation by cholinergic innervation.
J Neurosci Volume: 15 Page(s): 4077 - 4092
05/01/1995 Authors: Levey AI; Edmunds SM; Koliatsos V; Wiley RG; Heilman CJ -
Immunocytochemical localization of D1 and D2 dopamine receptors in the basal ganglia of the rat: light and electron microscopy.
Neuroscience Volume: 65 Page(s): 709 - 730
04/01/1995 Authors: Yung KK; Bolam JP; Smith AD; Hersch SM; Ciliax BJ; Levey AI -
Differential regulation of molecular subtypes of muscarinic receptors in Alzheimer's disease.
J Neurochem Volume: 64 Page(s): 1888 - 1891
04/01/1995 Authors: Flynn DD; Ferrari-DiLeo G; Mash DC; Levey AI -
The dopamine transporter: immunochemical characterization and localization in brain.
J Neurosci Volume: 15 Page(s): 1714 - 1723
03/01/1995 Authors: Ciliax BJ; Heilman C; Demchyshyn LL; Pristupa ZB; Ince E; Hersch SM; Niznik HB; Levey AI -
GUINEA-PIG TRACHEAL PARASYMPATHETIC NERVES IN PRIMARY CULTURE EXPRESS M(2) MUSCARINIC RECEPTORS
LIFE SCIENCES Volume: 56 Page(s): 1044 - 1044
02/10/1995 Authors: FRYER AD; ELBON CL; JORDAN KE; LEVEY AI -
Identification and characterization of antidepressant-sensitive serotonin transporter proteins using site-specific antibodies.
J Neurosci Volume: 15 Page(s): 1261 - 1274
02/01/1995 Authors: Qian Y; Melikian HE; Rye DB; Levey AI; Blakely RD -
Light and electron microscopic study of m2 muscarinic acetylcholine receptor in the basal forebrain of the rat.
J Comp Neurol Volume: 351 Page(s): 339 - 356
01/16/1995 Authors: Levey AI; Edmunds SM; Hersch SM; Wiley RG; Heilman CJ -
Down-regulation of AMPA receptor subunit GluR2 in amygdaloid kindling.
J Neurochem Volume: 64 Page(s): 462 - 465
01/01/1995 Authors: Prince HK; Conn PJ; Blackstone CD; Huganir RL; Levey AI -
Differential alterations in muscarinic receptor subtypes in Alzheimer's disease: implications for cholinergic-based therapies.
Life Sci Volume: 56 Page(s): 869 - 876
01/01/1995 Authors: Flynn DD; Ferrari-DiLeo G; Levey AI; Mash DC -
Diverse pre- and post-synaptic expression of m1-m4 muscarinic receptor proteins in neurons and afferents in the rat neostriatum.
Life Sci Volume: 56 Page(s): 931 - 938
01/01/1995 Authors: Hersch SM; Levey AI -
Localization of muscarinic m3 receptor protein and M3 receptor binding in rat brain.
Neuroscience Volume: 63 Page(s): 207 - 221
11/01/1994 Authors: Levey AI; Edmunds SM; Heilman CJ; Desmond TJ; Frey KA -
Localization of neuronal and glial glutamate transporters.
Neuron Volume: 13 Page(s): 713 - 725
09/01/1994 Authors: Rothstein JD; Martin L; Levey AI; Dykes-Hoberg M; Jin L; Wu D; Nash N; Kuncl RW -
D1 dopamine receptor immunoreactivity in human and monkey cerebral cortex: predominant and extrasynaptic localization in dendritic spines.
Proc Natl Acad Sci U S A Volume: 91 Page(s): 5720 - 5724
06/07/1994 Authors: Smiley JF; Levey AI; Ciliax BJ; Goldman-Rakic PS -
Distribution of m1-m4 muscarinic receptor proteins in the rat striatum: light and electron microscopic immunocytochemistry using subtype-specific antibodies.
J Neurosci Volume: 14 Page(s): 3351 - 3363
05/01/1994 Authors: Hersch SM; Gutekunst CA; Rees HD; Heilman CJ; Levey AI -
Sequestration of muscarinic cholinergic receptors in permeabilized neuroblastoma cells.
J Neurochem Volume: 62 Page(s): 1795 - 1803
05/01/1994 Authors: Slowiejko DM; Levey AI; Fisher SK -
Localization of D1 and D2 dopamine receptors in brain with subtype-specific antibodies.
Proc Natl Acad Sci U S A Volume: 90 Page(s): 8861 - 8865
10/01/1993 Authors: Levey AI; Hersch SM; Rye DB; Sunahara RK; Niznik HB; Kitt CA; Price DL; Maggio R; Brann MR; Ciliax BJ -
MOLECULAR PHARMACOLOGY OF DOPAMINERGIC AND CHOLINERGIC SYSTEMS IN THE BASAL GANGLIA
ANNALS OF NEUROLOGY Volume: 34 Page(s): 246 - 247
08/01/1993 Authors: LEVEY AI; HERSCH S; CILIAX B; RYE DB -
Association of m1 and m2 muscarinic receptor proteins with asymmetric synapses in the primate cerebral cortex: morphological evidence for cholinergic modulation of excitatory neurotransmission.
Proc Natl Acad Sci U S A Volume: 90 Page(s): 5194 - 5198
06/01/1993 Authors: Mrzljak L; Levey AI; Goldman-Rakic PS -
Cellular localizations of AMPA glutamate receptors within the basal forebrain magnocellular complex of rat and monkey.
J Neurosci Volume: 13 Page(s): 2249 - 2263
05/01/1993 Authors: Martin LJ; Blackstone CD; Levey AI; Huganir RL; Price DL -
AMPA glutamate receptor subunits are differentially distributed in rat brain.
Neuroscience Volume: 53 Page(s): 327 - 358
03/01/1993 Authors: Martin LJ; Blackstone CD; Levey AI; Huganir RL; Price DL -
Immunological localization of m1-m5 muscarinic acetylcholine receptors in peripheral tissues and brain.
Life Sci Volume: 52 Page(s): 441 - 448
01/01/1993 Authors: Levey AI -
Immunological detection of glutamate receptor subtypes in human central nervous system.
Ann Neurol Volume: 31 Page(s): 680 - 683
06/01/1992 Authors: Blackstone CD; Levey AI; Martin LJ; Price DL; Huganir RL -
Biochemical characterization and localization of a non-N-methyl-D-aspartate glutamate receptor in rat brain.
J Neurochem Volume: 58 Page(s): 1118 - 1126
03/01/1992 Authors: Blackstone CD; Moss SJ; Martin LJ; Levey AI; Price DL; Huganir RL -
Identification and localization of muscarinic acetylcholine receptor proteins in brain with subtype-specific antibodies.
J Neurosci Volume: 11 Page(s): 3218 - 3226
10/01/1991 Authors: Levey AI; Kitt CA; Simonds WF; Price DL; Brann MR -
Immunological detection of muscarinic receptor subtype proteins (m1-m5) in rabbit peripheral tissues.
Mol Pharmacol Volume: 40 Page(s): 459 - 462
10/01/1991 Authors: Drje F; Levey AI; Brann MR -
The dysarthria-clumsy hand syndrome: ataxic or bradykinetic hand?
Ann Neurol Volume: 30 Page(s): 430 - 431
09/01/1991 Authors: Grandas F; Villanueva JA; Mateo D; Gimenez-Roldn S -
D1 and D2 dopamine receptor mRNA in rat brain.
Proc Natl Acad Sci U S A Volume: 88 Page(s): 1859 - 1863
03/01/1991 Authors: Weiner DM; Levey AI; Sunahara RK; Niznik HB; O'Dowd BF; Seeman P; Brann MR -
Bacterial expression of human muscarinic receptor fusion proteins and generation of subtype-specific antisera.
FEBS Lett Volume: 275 Page(s): 65 - 69
11/26/1990 Authors: Levey AI; Stormann TM; Brann MR -
Expression of muscarinic acetylcholine and dopamine receptor mRNAs in rat basal ganglia.
Proc Natl Acad Sci U S A Volume: 87 Page(s): 7050 - 7054
09/01/1990 Authors: Weiner DM; Levey AI; Brann MR -
The dysarthria-clumsy hand syndrome: a distinct clinical entity related to pontine infarction.
Ann Neurol Volume: 27 Page(s): 487 - 494
05/01/1990 Authors: Glass JD; Levey AI; Rothstein JD -
Cholinergic vs. noncholinergic efferents from the mesopontine tegmentum to the extrapyramidal motor system nuclei.
J Comp Neurol Volume: 275 Page(s): 469 - 492
09/22/1988 Authors: Lee HJ; Rye DB; Hallanger AE; Levey AI; Wainer BH -
Nimodipine in acute ischemic stroke.
N Engl J Med Volume: 319 Page(s): 249 - 251
07/28/1988 -
NIMODIPINE IN ACUTE ISCHEMIC STROKE
NEW ENGLAND JOURNAL OF MEDICINE Volume: 319 Page(s): 250 - 250
07/28/1988 Authors: VORNOV JJ; LEVEY A -
COGNITIVE CONSEQUENCES OF MAGNETIC-RESONANCE IMAGING CONFIRMED LEFT THALAMIC INFARCTION
Volume: 24 Page(s): 126 - 127
07/01/1988 Authors: LEVEY A; WEISS H; BOLAWILSON K; GORDON B -
Seizures following myelography with iopamidol.
Ann Neurol Volume: 23 Page(s): 397 - 399
04/01/1988 Authors: Levey AI; Weiss H; Yu R; Wang H; Krumholz A -
Immunohistochemistry of choline acetyltransferase in the guinea pig brain.
Neurosci Lett Volume: 84 Page(s): 137 - 142
01/22/1988 Authors: Maley BE; Frick ML; Levey AI; Wainer BH; Elde RP -
SEIZURES FOLLOWING MYELOGRAPHY WITH IOPAMIDOL
EPILEPSIA Volume: 28 Page(s): 589 - 589
09/01/1987 Authors: LEVEY AI; WEISS HD; YU R; WANG H; KRUMHOLZ A -
The origins of cholinergic and other subcortical afferents to the thalamus in the rat.
J Comp Neurol Volume: 262 Page(s): 105 - 124
08/01/1987 Authors: Hallanger AE; Levey AI; Lee HJ; Rye DB; Wainer BH -
Choline acetyltransferase immunoreactivity in the rat thalamus.
J Comp Neurol Volume: 257 Page(s): 317 - 332
03/15/1987 Authors: Levey AI; Hallanger AE; Wainer BH -
Cholinergic nucleus basalis neurons may influence the cortex via the thalamus.
Neurosci Lett Volume: 74 Page(s): 7 - 13
02/10/1987 Authors: Levey AI; Hallanger AE; Wainer BH -
Substance P-containing terminals in synaptic contact with cholinergic neurons in the neostriatum and basal forebrain: a double immunocytochemical study in the rat.
Brain Res Volume: 397 Page(s): 279 - 289
11/12/1986 Authors: Bolam JP; Ingham CA; Izzo PN; Levey AI; Rye DB; Smith AD; Wainer BH -
A light and electron microscopic procedure for sequential double antigen localization using diaminobenzidine and benzidine dihydrochloride.
J Histochem Cytochem Volume: 34 Page(s): 1449 - 1457
11/01/1986 Authors: Levey AI; Bolam JP; Rye DB; Hallanger AE; Demuth RM; Mesulam MM; Wainer BH -
RELATIONSHIP OF SOMATOSTATIN AND CHOLINE-ACETYLTRANSFERASE IN CORTEX
ANATOMICAL RECORD Volume: 214 Page(s): A77 - A77
03/01/1986 Authors: LYSAKOWSKI A; LEVEY AI; WAINER BH -
Cholinergic and non-cholinergic septohippocampal pathways.
Neurosci Lett Volume: 54 Page(s): 45 - 52
02/28/1985 Authors: Wainer BH; Levey AI; Rye DB; Mesulam MM; Mufson EJ -
Choline acetyltransferase-like immunoreactivity in the forebrain of the red-eared pond turtle (Pseudemys scripta elegans).
Brain Res Volume: 323 Page(s): 103 - 108
12/03/1984 Authors: Mufson EJ; Desan PH; Mesulam MM; Wainer BH; Levey AI -
Choline acetyltransferase-immunoreactive neurons intrinsic to rodent cortex and distinction from acetylcholinesterase-positive neurons.
Neuroscience Volume: 13 Page(s): 341 - 353
10/01/1984 Authors: Levey AI; Wainer BH; Rye DB; Mufson EJ; Mesulam MM -
Atlas of cholinergic neurons in the forebrain and upper brainstem of the macaque based on monoclonal choline acetyltransferase immunohistochemistry and acetylcholinesterase histochemistry.
Neuroscience Volume: 12 Page(s): 669 - 686
07/01/1984 Authors: Mesulam MM; Mufson EJ; Levey AI; Wainer BH -
Cholinergic systems in mammalian brain identified with antibodies against choline acetyltransferase.
Neurochem Int Volume: 6 Page(s): 163 - 182
01/01/1984 Authors: Wainer BH; Levey AI; Mufson EJ; Mesulam MM -
Central cholinergic pathways in the rat: an overview based on an alternative nomenclature (Ch1-Ch6).
Neuroscience Volume: 10 Page(s): 1185 - 1201
12/01/1983 Authors: Mesulam MM; Mufson EJ; Wainer BH; Levey AI -
Co-localization of acetylcholinesterase and choline acetyltransferase in the rat cerebrum.
Neuroscience Volume: 9 Page(s): 9 - 22
05/01/1983 Authors: Levey AI; Wainer BH; Mufson EJ; Mesulam MM -
Distribution of cholinergic neurons in rat brain: demonstrated by the immunocytochemical localization of choline acetyltransferase.
J Comp Neurol Volume: 216 Page(s): 53 - 68
05/01/1983 Authors: Armstrong DM; Saper CB; Levey AI; Wainer BH; Terry RD -
Cholinergic innervation of cortex by the basal forebrain: cytochemistry and cortical connections of the septal area, diagonal band nuclei, nucleus basalis (substantia innominata), and hypothalamus in the rhesus monkey.
J Comp Neurol Volume: 214 Page(s): 170 - 197
02/20/1983 Authors: Mesulam MM; Mufson EJ; Levey AI; Wainer BH -
Monoclonal antibodies to choline acetyltransferase: production, specificity, and immunohistochemistry.
J Neurosci Volume: 3 Page(s): 1 - 9
01/01/1983 Authors: Levey AI; Armstrong DM; Atweh SF; Terry RD; Wainer BH -
Immunochemical studies of bovine and human choline-O-acetyltransferase using monoclonal antibodies.
J Neurochem Volume: 39 Page(s): 1652 - 1659
12/01/1982 Authors: Levey AI; Rye DB; Wainer BH -
Cross-species and intraspecies reactivities of monoclonal antibodies against choline acetyltransferase.
Brain Res Volume: 234 Page(s): 469 - 473
02/25/1982 Authors: Levey AI; Wainer BH -
The production of monoclonal antibodies reactive with bovine choline acetyltransferase.
Brain Res Volume: 218 Page(s): 383 - 387
08/10/1981 Authors: Levey AI; Aoki M; Fitch FW; Wainer BH -
MONOCLONAL-ANTIBODIES TO CHOLINE-ACETYLTRANSFERASE
FEDERATION PROCEEDINGS Volume: 40 Page(s): 270 - 270
01/01/1981 Authors: LEVEY AI; AOKI M; FITCH FW; WAINER BH