Arezou Khosroshahi
Overview
Dr. Arezou Khosroshahi received her medical degree from Tehran University Medical School in Iran. After finishing a postdoctoral research fellowship in the Transplantation Center at the Brigham and Womens Hospital, Harvard Medical School, she completed her internal medicine training at St. Lukes-Roosevelt Hospital Center, Columbia University. Upon completion of her clinical rheumatology fellowship at Massachusetts General Hospital, she became involved in exciting clinical research focused on a newly recognized condition called IgG4-related disease (IgG4-RD). Their group was one of the first in the country to become aware of and focus on this condition.
Dr. Khosroshahis efforts to understand different aspects of IgG4-RD over the past ten years have led to important contributions to the field of IgG4-RD, including adding new clinical manifestations to the list of organs involved with this protean disease and its responsiveness to B cell depletion. She co-directed the first two international symposiums on IgG4-RD to bring investigators from all around the world together and helped to establish the name of the disease, pathology statements for the diagnosis of this condition, and guidelines on the management of IgG4-RD. She is currently an active member of an international committee for the development of classification criteria and validation of IgG4-RD responder index.
Dr. Khosroshahi has established an IgG4-RD clinic at Emory since her arrival in 2013. This clinic is one of the few in the United States to evaluate and treat patients with IgG4-RD. Patients have the option to participate in multiple research projects related to this condition. She has developed close collaboration between clinicians in multiple specialties at Emory and scientists in Emorys Lowance Immunology Center to be able to diagnose, treat, and investigate many unknowns in regards to this novel condition.
She has been involved in Lupus Clinic at Grady Hospital for the past six years and recently established a new lupus clinic at Emory. She is the principal investigator for different clinical trials in lupus and is working closely with her colleagues Drs. Lim and Sanz to help understand many different aspects of lupus, with particular interest in treatment.
Dr. Khosroshahi has a particular interest in clinical education and works closely with Emory medical students, residents, and fellows at Grady Memorial Hospital and Emory University.
Academic Appointment
- Associate Professor of Medicine, Emory University School of Medicine
Education
Degrees
- MD from Tehran University of Medical Sciences
Research
Publications
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Renal arteriosclerosis in kidney biopsies associated with higher 10-year atherosclerotic cardiovascular disease in lupus nephritis.
Rheumatology (Oxford) Volume: 64 Page(s): 2665 - 2675
05/01/2025 Authors: Garg S; Astor BC; Lim SS; Raval AN; Zhong W; Panzer SE; Khosroshahi A; Rovin B; Bartels CM -
Inebilizumab for Treatment of IgG4-Related Disease.
N Engl J Med Volume: 392 Page(s): 1168 - 1177
03/27/2025 Authors: Stone JH; Khosroshahi A; Zhang W; Della Torre E; Okazaki K; Tanaka Y; Lhr JM; Schleinitz N; Dong L; Umehara H -
Unlocking disease insights to facilitate drug development: Pharmaceutical industry-academia collaborations in inflammation and immunology.
Drug Discov Today Volume: 30 Page(s): 104317
03/01/2025 Authors: Peeva E; Guttman-Yassky E; Yamaguchi Y; Berman B; Oemar B; Ramakrishna J; Fasano A; Evans-Molina C; Chu M; Ungar B -
Multi-centered clinical validation demonstrating superior precision in lupus diagnosis: T cell autoantibodies and TC4d outperform conventional lupus erythematosus biomarkers.
Front Immunol Volume: 16 Page(s): 1518208
01/01/2025 Authors: Kyttaris V; Wallace DJ; Khosroshahi A; Concoff A; Wilson N; Liu CC; Manzi S; Ahearn J; Taghavi S; Warsi T -
Publisher Correction: Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE.
Nat Immunol Volume: 26 Page(s): 148
01/01/2025 Authors: Faliti CE; Van TTP; Anam FA; Cheedarla N; Williams ME; Mishra AK; Usman SY; Woodruff MC; Kraker G; Runnstrom MC -
Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE.
Nat Immunol Volume: 26 Page(s): 131 - 145
01/01/2025 Authors: Faliti CE; Van TTP; Anam FA; Cheedarla N; Williams ME; Mishra AK; Usman SY; Woodruff MC; Kraker G; Runnstrom MC -
Multiplicative Impact of Adverse Social Determinants of Health on Outcomes in Lupus Nephritis: A Meta-analysis and Systematic Review.
Arthritis Care Res (Hoboken) Volume: 76 Page(s): 1232 - 1245
09/01/2024 Authors: Garg S; Sweet N; Boderman B; Montes D; Walunas T; Ramsey-Goldman R; Khosroshahi A; Astor BC; Lim SS; Bartels CM -
Associations between TCA cycle plasma metabolites and fatigue in black females with systemic lupus erythematosus: An untargeted metabolomics pilot study.
Lupus Volume: 33 Page(s): 948 - 961
08/01/2024 Authors: Kimble LP; Khosroshahi A; Brewster GS; Dunbar SB; Ryan D; Carlson N; Eldridge R; Houser M; Corwin E -
Factors associated with immune responses to SARS-CoV-2 vaccination in individuals with autoimmune diseases.
JCI Insight Volume: 9
06/04/2024 Authors: Anderson E; Powell M; Yang E; Kar A; Leung TM; Sison C; Steinberg R; Mims R; Choudhury A; Espinosa C -
Distinct transcriptomes and autocrine cytokines underpin maturation and survival of antibody-secreting cells in systemic lupus erythematosus.
Nat Commun Volume: 15 Page(s): 1899
03/01/2024 Authors: Chen W; Hong S-H; Jenks SA; Anam FA; Tipton CM; Woodruff MC; Hom JR; Cashman KS; Faliti CE; Wang X