Xiaonan Wang MD, MS
Overview
Dr. Xiaonan Wang received her MS in biochemistry from Peking Union Medical College, China and her MD from China Medical University. After receiving her MD, she accepted a position as an attending physician at the PUMC Hospital in China. In 1997, Dr. Wang joined the Division of Renal Medicine at Emory University as an instructor, and in May of 2001, she was named an assistant professor of medicine.
The objective of Dr. Wang's research is to identify molecular and biochemical mechanisms that lead to protein malnutrition in catabolic diseases related to insulin resistance, such as chronic renal disease and diabetes. She uses transgenic mice and cell culture systems to test her hypotheses. Currently, she is exploring the use of gene therapy (using lentiviruses to deliver target genes) to treat muscle protein loss in insulin-deficient diabetic animals.
Academic Appointment
- Assistant Professor, Department of Medicine
Education
Degrees
- MS from Peking Union Medical College
- MD from China Medical University
Research
Focus
- Muscle physiology and pathology in catabolic disease (CKD and diabetes), aging and exercise
Publications
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Protein-energy wasting in chronic kidney disease: mechanisms responsible for loss of muscle mass and function.
Kidney Res Clin Pract
02/21/2025 Authors: Price SR; Wang XH -
The gut microbiome, chronic kidney disease, and sarcopenia.
Cell Commun Signal Volume: 22 Page(s): 558
11/21/2024 Authors: Zheng G; Cao J; Wang XH; He W; Wang B -
Endurance Exercise-Induced Fgf21 Promotes Skeletal Muscle Fiber Conversion through TGF-1 and p38 MAPK Signaling Pathway.
Int J Mol Sci Volume: 24
07/13/2023 Authors: Luo X; Zhang H; Cao X; Yang D; Yan Y; Lu J; Wang X; Wang H -
Organ Crosstalk Contributes to Muscle Wasting in Chronic Kidney Disease.
Semin Nephrol Volume: 43 Page(s): 151409
03/01/2023 Authors: Wang XH; Price SR -
The impact of senescence on muscle wasting in chronic kidney disease.
J Cachexia Sarcopenia Muscle Volume: 14 Page(s): 126 - 141
02/01/2023 Authors: Huang Y; Wang B; Hassounah F; Price SR; Klein J; Mohamed TMA; Wang Y; Park J; Cai H; Zhang X -
Pathophysiological mechanisms leading to muscle loss in chronic kidney disease.
Nat Rev Nephrol Volume: 18 Page(s): 138 - 152
03/01/2022 Authors: Wang XH; Mitch WE; Price SR -
Downregulation of let-7 by Electrical Acupuncture Increases Protein Synthesis in Mice.
Front Physiol Volume: 12 Page(s): 697139
01/01/2021 Authors: Huang Y; Yu M; Kuma A; Klein JD; Wang Y; Hassounah F; Cai H; Wang XH -
MicroRNA-223-3p inhibits vascular calcification and the osteogenic switch of vascular smooth muscle cells.
J Biol Chem Volume: 296 Page(s): 100483
01/01/2021 Authors: Han Y; Zhang J; Huang S; Cheng N; Zhang C; Li Y; Wang X; Liu J; You B; Du J -
MicroRNA-223-3p promotes skeletal muscle regeneration by regulating inflammation in mice.
J Biol Chem Volume: 295 Page(s): 10212 - 10223
07/24/2020 Authors: Cheng N; Liu C; Li Y; Gao S; Han Y-C; Wang X; Du J; Zhang C -
14-3-3, a novel regulator of the large-conductance Ca2+-activated K+ channel.
Am J Physiol Renal Physiol Volume: 319 Page(s): F52 - F62
07/01/2020 Authors: Chen S; Feng X; Chen X; Zhuang Z; Xiao J; Fu H; Klein JD; Wang XH; Hoover RS; Eaton DC