Publications

• The Impact of Video-assisted Thoracoscopic Versus Percutaneous Tunneled Pleural Catheter Techniques on Pleurodesis Outcomes: A Retrospective, Single-center Study.
  J Bronchology Interv Pulmonol Volume: 32
  04/01/2025 Authors: Lin J; Chaddha U; Urrutia-Royo B; Ravikumar N; Bhavani SV; Katsis J; Ferguson MK; Murgu S
• Correction: A common longitudinal intensive care unit data format (CLIF) for critical illness research.
  Intensive Care Med Volume: 51 Page(s): 836 - 839
  04/01/2025 Authors: Rojas JC; Lyons PG; Chhikara K; Chaudhari V; Bhavani SV; Nour M; Buell KG; Smith KD; Gao CA; Amagai S
• A common longitudinal intensive care unit data format (CLIF) for critical illness research.
  Intensive Care Med Volume: 51 Page(s): 556 - 569
  03/01/2025 Authors: Rojas JC; Lyons PG; Chhikara K; Chaudhari V; Bhavani SV; Nour M; Buell KG; Smith KD; Gao CA; Amagai S
• Distinct immune profiles and clinical outcomes in sepsis subphenotypes based on temperature trajectories.
  Intensive Care Med Volume: 50 Page(s): 2094 - 2104
  12/01/2024 Authors: Bhavani SV; Spicer A; Sinha P; Malik A; Lopez-Espina C; Schmalz L; Watson GL; Bhargava A; Khan S; Urdiales D
• Response.
  Chest Volume: 166 Page(s): e126
  10/01/2024 Authors: Bhavani SV; Coopersmith CM
• Development and Validation of a Machine Learning Model for Early Detection of Untreated Infection.
  Crit Care Explor Volume: 6 Page(s): e1165
  10/01/2024 Authors: Buell KG; Carey KA; Dussault N; Parker WF; Dumanian J; Bhavani SV; Gilbert ER; Winslow CJ; Shah NS; Afshar M
• A Common Longitudinal Intensive Care Unit data Format (CLIF) to enable multi-institutional federated critical illness research.
  medRxiv
  09/04/2024 Authors: Rojas JC; Lyons PG; Chhikara K; Chaudhari V; Bhavani SV; Nour M; Buell KG; Smith KD; Gao CA; Amagai S
• The Precision Resuscitation With Crystalloids in Sepsis (PRECISE) Trial: A Trial Protocol.
  JAMA Netw Open Volume: 7 Page(s): e2434197
  09/03/2024 Authors: Bhavani SV; Holder A; Miltz D; Kamaleswaran R; Khan S; Easley K; Murphy DJ; Franks N; Wright DW; Kraft C
• Definitions and Denominators ICU Utilization: What Do the Numbers Really Tell Us?
  Crit Care Med Volume: 52 Page(s): 1478 - 1481
  09/01/2024 Authors: Kempker JA; Bhavani SV
• Using Trajectories of Bedside Vital Signs to Identify COVID-19 Subphenotypes.
  Chest Volume: 165 Page(s): 529 - 539
  03/01/2024 Authors: Bhavani SV; Robichaux C; Verhoef PA; Churpek MM; Coopersmith CM
• Racial Differences in Accuracy of Predictive Models for High-Flow Nasal Cannula Failure in COVID-19.
  Crit Care Explor Volume: 6 Page(s): e1059
  03/01/2024 Authors: Yang P; Gregory IA; Robichaux C; Holder AL; Martin GS; Esper AM; Kamaleswaran R; Gichoya JW; Bhavani SV
• Saved by the Bell-Automated Paging Alerts to Improve Sepsis Bundle Compliance.
  Crit Care Med Volume: 52 Page(s): 340 - 342
  02/01/2024 Authors: Bhavani SV; Mohr N
• MULTIPAR: Supervised Irregular Tensor Factorization with Multi-task Learning for Computational Phenotyping.
  Volume: 225 Page(s): 498 - 511
  12/01/2023 Authors: Ren Y; Lou J; Xiong L; Ho JC; Jiang X; Bhavani SV
• HIRA: Heart Rate Interval based Rapid Alert score to characterize autonomic dysfunction among patients with sepsis-related acute respiratory failure (ARF).
  Physiol Meas Volume: 44
  10/13/2023 Authors: Krishnan P; Rad MG; Agarwal P; Marshall C; Yang P; Bhavani SV; Holder AL; Esper A; Kamaleswaran R
• Leveraging Data Science and Novel Technologies to Develop and Implement Precision Medicine Strategies in Critical Care.
  Crit Care Clin Volume: 39 Page(s): 627 - 646
  10/01/2023 Authors: Sanchez-Pinto LN; Bhavani SV; Atreya MR; Sinha P
• Factors Associated With Diagnostic Accuracy of Robotic Bronchoscopy With 12-Month Follow-up.
  Ann Thorac Surg Volume: 115 Page(s): 1361 - 1368
  06/01/2023 Authors: Agrawal A; Ho E; Chaddha U; Demirkol B; Bhavani SV; Hogarth DK; Murgu S
• Comparison of time series clustering methods for identifying novel subphenotypes of patients with infection.
  J Am Med Inform Assoc Volume: 30 Page(s): 1158 - 1166
  05/19/2023 Authors: Bhavani SV; Xiong L; Pius A; Semler M; Qian ET; Verhoef PA; Robichaux C; Coopersmith CM; Churpek MM
• Temperature Trajectory Subphenotypes in Oncology Patients with Neutropenia and Suspected Infection.
  Am J Respir Crit Care Med Volume: 207 Page(s): 1300 - 1309
  05/15/2023 Authors: Benzoni NS; Carey KA; Bewley AF; Klaus J; Fuller BM; Edelson DP; Churpek MM; Bhavani SV; Lyons PG
• A Need for Prospective Long-Term Data to Characterize Cardiovascular Risk Factors in Sepsis Survivors.
  Crit Care Med Volume: 51 Page(s): 549 - 550
  04/01/2023 Authors: Bhavani SV
• Racial Differences in Detection of Fever Using Temporal vs Oral Temperature Measurements-Reply.
  JAMA Volume: 329 Page(s): 342 - 343
  01/24/2023 Authors: Bhavani SV; Wiley Z; Ofotokun I
• Development and validation of novel sepsis subphenotypes using trajectories of vital signs.
  Intensive Care Med Volume: 48 Page(s): 1582 - 1592
  11/01/2022 Authors: Bhavani SV; Semler M; Qian ET; Verhoef PA; Robichaux C; Churpek MM; Coopersmith CM
• Hospital trajectories and early predictors of clinical outcomes differ between SARS-CoV-2 and influenza pneumonia.
  EBioMedicine Volume: 85 Page(s): 104295
  11/01/2022 Authors: Lyons PG; Bhavani SV; Mody A; Bewley A; Dittman K; Doyle A; Windham SL; Patel TM; Raju BN; Keller M
• Identifying infected patients using semi-supervised and transfer learning.
  J Am Med Inform Assoc Volume: 29 Page(s): 1696 - 1704
  09/12/2022 Authors: Bashiri FS; Caskey JR; Mayampurath A; Dussault N; Dumanian J; Bhavani SV; Carey KA; Gilbert ER; Winslow CJ; Shah NS
• Racial Differences in Detection of Fever Using Temporal vs Oral Temperature Measurements in Hospitalized Patients.
  JAMA Volume: 328 Page(s): 885 - 886
  09/06/2022 Authors: Bhavani SV; Wiley Z; Verhoef PA; Coopersmith CM; Ofotokun I
• A Call for a Consensus Approach to the Design, Implementation, and Evaluation of Early Warning Systems.
  Crit Care Med Volume: 50 Page(s): 1280 - 1282
  08/01/2022 Authors: Bhavani SV
• Environmental and Social Determinants of Fever in COVID-19
  Volume: 205
  05/01/2022 Authors: Bhavani S; Edathara N; Lyons PG; Luo Y; Wiley Z; Mao C; Bewley A; Robichaux C; Verhoef PA; Coopersmith C
• Coronavirus Disease 2019 Temperature Trajectories Correlate With Hyperinflammatory and Hypercoagulable Subphenotypes.
  Crit Care Med Volume: 50 Page(s): 212 - 223
  02/01/2022 Authors: Bhavani SV; Verhoef PA; Maier CL; Robichaux C; Parker WF; Holder A; Kamaleswaran R; Wang MD; Churpek MM; Coopersmith CM
• Longitudinal respiratory subphenotypes in patients with COVID-19-related acute respiratory distress syndrome: results from three observational cohorts.
  Lancet Respir Med Volume: 9 Page(s): 1377 - 1386
  12/01/2021 Authors: Bos LDJ; Sjoding M; Sinha P; Bhavani SV; Lyons PG; Bewley AF; Botta M; Tsonas AM; Serpa Neto A; Schultz MJ
• Simulation of Ventilator Allocation in Critically Ill Patients with COVID-19.
  Am J Respir Crit Care Med Volume: 204 Page(s): 1224 - 1227
  11/15/2021 Authors: Bhavani SV; Luo Y; Miller WD; Sanchez-Pinto LN; Han X; Mao C; Sandk B; Peek ME; Coopersmith CM; Michelson KN
• Determining the Electronic Signature of Infection in Electronic Health Record Data.
  Crit Care Med Volume: 49 Page(s): e673 - e682
  07/01/2021 Authors: Churpek MM; Dumanian J; Dussault N; Bhavani SV; Carey KA; Gilbert ER; Arain E; Ye C; Winslow CJ; Shah NS
• Examining the Association Between Angiopoietin-2 Levels and Acute Respiratory Distress Syndrome Subtypes in Critically Ill Patients with Sepsis
  Volume: 203
  05/01/2021 Authors: Yang P; Sun D; Manatunga A; Harris F; Wells L; Bhavani S; Martin GS; Esper AM
• Body Temperature Trajectory Associated with Venous Thromboembolism in COVID-19 Patients
  Volume: 203
  05/01/2021 Authors: Bhavani S; Holder A; Kamaleswaran R; Verhoef PA; Churpek MM; Wang M; Coopersmith C
• Predictors of Hospital Outcomes and Clinical Subphenotypes Differ Between COVID-19 and Influenza Pneumonia
  Volume: 203
  05/01/2021 Authors: Lyons PG; Bhavani S; Michelson AP; Kannampallil T; Sinha P
• Temperature Trajectory Subphenotypes and Associated Outcomes Among Neutropenic Patients
  Volume: 203
  05/01/2021 Authors: Benzoni N; Bhavani S; Fuller B; Lyons PG
• Examining the Association Between Angiopoietin-2 Levels and Acute Respiratory Distress Syndrome Subtypes in Critically Ill Patients with Sepsis
  AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 203 Page(s): A2669 - A2669
  05/01/2021 Authors: Yang P; Sun D; Manatunga A; Harris F; Wells L; Bhavani S; Martin GS; Esper AM
• Thoracic ultrasound as a predictor of pleurodesis success at the time of indwelling pleural catheter removal.
  Respirology Volume: 26 Page(s): 249 - 254
  03/01/2021 Authors: Chaddha U; Agrawal A; Bhavani SV; Sivertsen K; Donington DJ; Ferguson MK; Murgu S
• Factors Affecting the Diagnostic Yield of Robot-Assisted Bronchoscopy for Pulmonary Lesions
  Volume: 16 Page(s): S135 - S135
  03/01/2021 Authors: Agrawal A; Chaddha U; Demirkol B; Bhavani S; Hogarth K; Murgu S
• Novel Temperature Trajectory Subphenotypes inCOVID-19.
  Chest Volume: 158 Page(s): 2436 - 2439
  12/01/2020 Authors: Bhavani SV; Huang ES; Verhoef PA; Churpek MM
• Temperature Trajectory Subphenotypes Correlate With Immune Responses in Patients With Sepsis.
  Crit Care Med Volume: 48 Page(s): 1645 - 1653
  11/01/2020 Authors: Bhavani SV; Wolfe KS; Hrusch CL; Greenberg JA; Krishack PA; Lin J; Lecompte-Osorio P; Carey KA; Kress JP; Coopersmith CM
• The Development and Validation of a Machine Learning Model to Predict Bacteremia and Fungemia in Hospitalized Patients Using Electronic Health Record Data.
  Crit Care Med Volume: 48 Page(s): e1020 - e1028
  11/01/2020 Authors: Bhavani SV; Lonjers Z; Carey KA; Afshar M; Gilbert ER; Shah NS; Huang ES; Churpek MM
• TEMPERATURE TRAJECTORY MAY BE AN INDICATOR OF BACTEREMIA IN PATIENTS WITH SEPTIC SHOCK
  Volume: 158 Page(s): 592A - 593A
  10/01/2020 Authors: Osorio PL; Bhavani S; Lin J; Patel B; Sperling A; Churpek M; Verhoef P; Kress J; Wolfe K
• Reply to Maitra and Bhattacharjee: Adherence to the Prevailing Sepsis Definition Is Quintessential to Subphenotype Identification.
  Am J Respir Crit Care Med Volume: 201 Page(s): 258 - 259
  01/15/2020 Authors: Bhavani SV; Verhoef PA; Churpek MM
• Development and Validation of Machine Learning Models to Predict Bacteremia and Fungemia Using Electronic Health Record (EHR) Data
  Volume: 201
  01/01/2020 Authors: Bhavani S; Lonjers Z; Carey K; Gilbert ER; Afshar M; Shah N; Huang E; Churpek MM
• Factors Associated with Pleurodesis Success in Patients with Tunneled Pleural Catheters Inserted for Treatment of Symptomatic Recurrent Pleural Effusions
  Volume: 201
  01/01/2020 Authors: Lin J; Chaddha US; Bhavani S; Katsis J; Murgu S
• Temperature Trajectory Subphenotypes Reveal Differential Response to Corticosteroids in Septic Shock
  Volume: 201
  01/01/2020 Authors: Waxse B; Bhavani S; Carey K; Huang E; Verhoef PA; Churpek MM
• Robot-assisted bronchoscopy for pulmonary lesion diagnosis: results from the initial multicenter experience.
  BMC Pulm Med Volume: 19 Page(s): 243
  12/11/2019 Authors: Chaddha U; Kovacs SP; Manley C; Hogarth DK; Cumbo-Nacheli G; Bhavani SV; Kumar R; Shende M; Egan JP; Murgu S
• Allergic Immune Diseases and the Risk of Mortality Among Patients Hospitalized for Acute Infection.
  Crit Care Med Volume: 47 Page(s): 1735 - 1742
  12/01/2019 Authors: Verhoef PA; Bhavani SV; Carey KA; Churpek MM
• PREDICTING BACTEREMIA USING ELECTRONIC HEALTH RECORD DATA
  Volume: 156 Page(s): 1607A - 1607A
  10/01/2019 Authors: Lonjers Z; Bhavani S; Carey K; Gilbert E; Afshar M; Churpek M
• Identifying Novel Sepsis Subphenotypes Using Temperature Trajectories.
  Am J Respir Crit Care Med Volume: 200 Page(s): 327 - 335
  08/01/2019 Authors: Bhavani SV; Carey KA; Gilbert ER; Afshar M; Verhoef PA; Churpek MM
• Reply to Leijte et al.: Fever in Sepsis: Still a Hot Topic.
  Am J Respir Crit Care Med Volume: 200 Page(s): 264 - 265
  07/15/2019 Authors: Bhavani SV; Verhoef PA; Churpek MM
• ASSOCIATION BETWEEN TEMPERATURE TRAJECTORY AND CYTOKINE SIGNATURES IN PATIENTS WITH STAPHYLOCOCCUS AUREUS BACTEREMIA
  Volume: 67 Page(s): 931 - 932
  06/01/2019 Authors: Bhavani S; Greenberg J; Carey KA; Sperling A; Churpek MM; Verhoef PA
• Impact of a Resident-Centered Interprofessional Quality Improvement Intervention on Acute Care Length of Stay.
  J Healthc Qual Volume: 41 Page(s): 212 - 219
  01/01/2019 Authors: Walker M; Gay L; Raynaldo G; Von Marensdorff H; Bates JT; Friedland JA; Park JH; Kehl E; Sowers B; Bhavani S
• Association Between Temperature Trajectory and Cytokine Signatures in Patients with Staphylococcus Aureus Bacteremia
  Volume: 199
  01/01/2019 Authors: Bhavani S; Greenberg JA; Hrusch C; Carey K; Sperling A; Churpek MM; Verhoef PA
• Cement cardiac embolism following kyphoplasty noted on thoracic imaging.
  Radiol Case Rep Volume: 13 Page(s): 914 - 916
  08/01/2018 Authors: Oshinsky C; Bhavani S; Funaki A
• Association Between Temperature Variability and Mortality in Hospitalized Patients with Infection
  Volume: 197
  01/01/2018 Authors: Bhavani S; Carey K; Edelson D; Churpek MM
• Comparing Retrospective Methods of Identifying Patients with Infection
  Volume: 197
  01/01/2018 Authors: Dumanian J; Dussault N; Bhavani S; Carey K; Venable LR; Edelson D; Churpek M
• Blastomycosis-Related Acute Respiratory Distress Syndrome Successfully Managed with Extracorporeal Membrane Oxygenation
  Volume: 197
  01/01/2018 Authors: Pearson SD; Bhavani S; Katsis J; Banach B; Antic T; Patel BK; Naureckas ET
• Using Machine Learning to Identify Infection Upon Presentation to the Hospital
  Volume: 197
  01/01/2018 Authors: Dussault N; Dumanian J; Bhavani S; Carey K; Edelson D; Venable L; Churpek MM
• Calcified cauliflower ear in relapsing polychondritis.
  BMJ Case Rep Volume: 2017
  04/21/2017 Authors: Mohan V; Bhavani S; Subramanian SK; Maiti A
• Bag Score: An ICU Survival Scoring System in a Veteran Population
  Volume: 150 Page(s): 214A - 214A
  10/01/2016 Authors: Yau S; Bhavani S; Lan C; Nair K; Li G; Perusich S
• Clinical and Immunological Factors in Emphysema Progression. Five-Year Prospective Longitudinal Exacerbation Study of Chronic Obstructive Pulmonary Disease (LES-COPD).
  Am J Respir Crit Care Med Volume: 192 Page(s): 1171 - 1178
  11/15/2015 Authors: Bhavani S; Tsai C-L; Perusich S; Hesselbacher S; Coxson H; Pandit L; Corry DB; Kheradmand F
• Loss of Peripheral Tolerance in Emphysema. Phenotypes, Exacerbations, and Disease Progression.
  Ann Am Thorac Soc Volume: 12 Suppl 2 Page(s): S164 - S168
  11/01/2015 Authors: Bhavani S; Yuan X; You R; Shan M; Corry D; Kheradmand F
• THE IMPACT OF A PATIENT-CENTERED MEDICAL HOME ON VET; ERANS WITH DIABETES MELLITUS
  Volume: 29 Page(s): S227 - S227
  04/01/2014 Authors: Bhavani S; Spiegelman A; Ghosh U; Vasudevan MM