Emory Urologic Surgery Research & Clinical Trials

Prospective Randomized Study of Exercise in Patients Undergoing Urologic Surgery

Inclusion Criteria:

• Adult patients scheduled for operative procedure with an inpatient postoperative stay

• Willing and able to give blood samples, complete a questionnaire, fill out the step log, and return to clinic for 1st post-operative appointment

Exclusion Criteria:

• None

Treatment:

Patients are given a pedometer and asked to record their daily steps in a log. The purpose of this study is to determine if pedometers can aid in increasing patients' physical activity during the perioperative period.

Principal Investigators:

Kenneth Ogan, MD; Viraj Master, MD, PhD; John Pattaras, MD

Frailty as a Predictor of Outcomes in Surgical Patients

Inclusion Criteria:

• Patients already scheduled for major surgery requiring an overnight hospital stay that are willing to do the study’s preoperative assessment tools

• Patients must be able to give informed consent and be 18 years and older

Exclusion Criteria:

• Patients diagnosed with severe dementia, Parkinson’s disease, or other functional motor disorders

• Patients diagnosed with a stroke and who have residual motor and/or cognitive deficits

• Patients taking carbidopa/levodopa, donepezil hydrochloride, or antidepressant medications

Principal Investigators:

Kenneth Ogan, MD; Viraj Master, MD, PhD

Co-Investigators & Collaborators: 

John Pattaras, MD, and three surgeons from the Department of Surgery: John Sweeney, MD; David Kooby, MD; Shishir Maithel, MD

Pilot Study of Biomarker Evaluation and Safety of Pre-Incisional Ketorolac for Patients Undergoing Surgical Resection for Non-Small Cell Lung Cancer and Renal Cell Carcinoma

Inclusion Criteria:

• Pathology-proven or suspected stage 1 or 2 NSCL and Stage 3 T3N0 RCC that require surgical resection as the treatment of choice

• ECOG performance status (PS) 0, 1, or 2

• Age ≥ 18 years and ≤80 years

Exclusion Criteria:

• Individuals with pure lung ground-glass opacity (GGO) lesions or mixed GGO with <50% solid component

• Patients undergoing pneumonectomy

• History of cancer in the three years prior to surgery (except for basal-cell carcinoma of the skin or cervical neoplasia)

• Contraindication for NSAIDs (peptic ulcer disease, pre-operative chronic kidney disease with eGFR <60 measured with the MDRD equation used widely, including at Emory>, allergies or intolerance to NSAIDs, coagulation disorder, or age > 80 years)

• Having taken an NSAID within five days prior to surgery

• Immunocompromised status

• Refusal or inability to understand the protocol and consent form or to receive follow-up in line with the recommendations

• Preoperative hemoglobin < 9.0

Principal Investigator: 

Viraj Master, MD, PhD

Co-Investigators & Collaborators: 

Onkar Khullar, MD (Department of Surgery); Haydn Kissick, PhD; Manoj Bhasin, PhD, MS (Department of Pediatrics and Department of Biomedical Informatics); Yuan Liu, PhD, MS (Department of Bioinformatics)

Urinary Microbiome in Catheter Associated Urinary Tract Infections

Inclusion Criteria:

• 18 years of age

• Chronic catheter > 12 months

Exclusion Criteria:

• Calculus disease

• Genitourinary anatomic abnormality or prior reconstruction procedure

• Immunosuppressed

• Current or chronic antibiotic treatment

Principal Investigator: 

Brendan Browne, MD