Publications

• TGF- mediates epigenetic control of innate antiviral responses and SIV reservoir size.
  Res Sq
  03/19/2025 Authors: Ghneim K; Ten-Caten F; Santana AC; Latif MB; Dinamarca DAD; Garca-Salum T; Estrada PMDR; Sohal P; Strongin Z; Harper J
• Author Correction: Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption.
  Nat Immunol Volume: 26 Page(s): 524
  03/01/2025 Authors: Pereira Ribeiro S; Strongin Z; Soudeyns H; Ten-Caten F; Ghneim K; Pacheco Sanchez G; Xavier de Medeiros G; Del Rio Estrada PM; Pelletier A-N; Hoang T
• Treatment of non-Hodgkin lymphoma with point-of-care manufactured CAR T cells: a dual institution, phase 1 trial.
  EClinicalMedicine Volume: 81 Page(s): 103138
  03/01/2025 Authors: Ghobadi A; Caimi PF; Reese JS; Goparaju K; di Trani M; Ritchey J; Jackson Z; Tomlinson B; Schiavone JM; Kleinsorge-Block S
• Human immune organoids to decode B cell response in healthy donors and patients with lymphoma.
  Nat Mater Volume: 24 Page(s): 297 - 311
  02/01/2025 Authors: Zhong Z; Quiones-Prez M; Dai Z; Juarez VM; Bhatia E; Carlson CR; Shah SB; Patel A; Fang Z; Hu T
• Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients.
  Nat Commun Volume: 16 Page(s): 586
  01/10/2025 Authors: Pickering H; Schaenman J; Phan HV; Maguire C; Tsitsiklis A; Rouphael N; Higuita NIA; Atkinson MA; Brakenridge S; Fung M
• The immune-endocrine interplay in sex differential responses to viral infection and COVID-19.
  Trends Immunol Volume: 45 Page(s): 943 - 958
  12/01/2024 Authors: D'Onofrio V; Skaly RP
• Assessing advances in three decades of clinical antiretroviral therapy on the HIV-1 reservoir.
  J Clin Invest Volume: 135
  11/29/2024 Authors: Gonzlez-Navarro I; Urrea V; Glvez C; Garcia-Guerrero MDC; Morn-Lpez S; Puertas MC; Grau E; Mothe B; Bailn L; Miranda C
• Sirolimus reduces Tcell cycling, immune checkpoint marker expression, and HIV-1 DNA in people with HIV.
  Cell Rep Med Volume: 5 Page(s): 101745
  10/15/2024 Authors: Henrich TJ; Bosch RJ; Godfrey C; Mar H; Nair A; Keefer M; Fichtenbaum C; Moisi D; Clagett B; Buck AM
• Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption.
  Nat Immunol Volume: 25 Page(s): 1900 - 1912
  10/01/2024 Authors: Pereira Ribeiro S; Strongin Z; Soudeyns H; Ten-Caten F; Ghneim K; Pacheco Sanchez G; Xavier de Medeiros G; Del Rio Estrada PM; Pelletier A-N; Hoang T
• Administration of anti-HIV-1 broadly neutralizing monoclonal antibodies with increased affinity to Fc receptors during acute SHIVAD8-EO infection.
  Nat Commun Volume: 15 Page(s): 7461
  08/29/2024 Authors: Dias J; Fabozzi G; Fourati S; Chen X; Liu C; Ambrozak DR; Ransier A; Laboune F; Hu J; Shi W
• Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2 in mice.
  Sci Transl Med Volume: 16 Page(s): eado1941
  08/21/2024 Authors: Desai P; Karl CE; Ying B; Liang C-Y; Garcia-Salum T; Santana AC; Ten-Caten F; Joseph F Urban; Elbashir SM; Edwards DK
• Neutralization activity in chronic HIV infection is characterized by a distinct programming of follicular helper CD4 T cells.
  bioRxiv
  08/03/2024 Authors: Moysi E; Sharma AA; O'Dell S; Georgakis S; Del Rio Estrada PM; Torres-Ruiz F; Navarro MG; Villalobos YAL; Rios SA; Reyes-Teran G
• A pre-vaccination immune metabolic interplay determines the protective antibody response to a dengue virus vaccine.
  Cell Rep Volume: 43 Page(s): 114370
  07/23/2024 Authors: Pelletier A-N; Sanchez GP; Izmirly A; Watson M; Di Pucchio T; Carvalho KI; Filali-Mouhim A; Paramithiotis E; Timenetsky MDCST; Precioso AR
• Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence.
  Nat Immunol Volume: 25 Page(s): 1245 - 1256
  07/01/2024 Authors: Strongin Z; Raymond Marchand L; Deleage C; Pampena MB; Cardenas MA; Beusch CM; Hoang TN; Urban EA; Gourves M; Nguyen K
• Single-cell analysis reveals an antiviral network that controls Zika virus infection in human dendritic cells.
  J Virol Volume: 98 Page(s): e0019424
  05/14/2024 Authors: Moore KM; Pelletier A-N; Lapp S; Metz A; Tharp GK; Lee M; Bhasin SS; Bhasin M; Skaly R-P; Bosinger SE
• Integrated longitudinal multiomics study identifies immune programs associated with acute COVID-19 severity and mortality.
  J Clin Invest Volume: 134
  05/01/2024 Authors: Gygi JP; Maguire C; Patel RK; Shinde P; Konstorum A; Shannon CP; Xu L; Hoch A; Jayavelu ND; Haddad EK
• Single cell analysis reveals an antiviral network that controls Zika virus infection in human dendritic cells.
  
  01/21/2024 Authors: Moore KM; Pelletier A-N; Lapp S; Metz A; Tharp GK; Lee M; Bhasin SS; Bhasin M; Skaly R-P; Bosinger SE
• Intestinal helminth infection impairs vaccine-induced T cell responses and protection against SARS-CoV-2.
  bioRxiv
  01/15/2024 Authors: Desai P; Karl CE; Ying B; Liang C-Y; Garcia-Salum T; Santana AC; Caten FT; Urban JF; Elbashir SM; Edwards DK
• IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition.
  Nat Commun Volume: 15 Page(s): 404
  01/09/2024 Authors: Haslund-Gourley BS; Woloszczuk K; Hou J; Connors J; Cusimano G; Bell M; Taramangalam B; Fourati S; Mege N; Bernui M
• Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study.
  Nat Commun Volume: 15 Page(s): 216
  01/03/2024 Authors: Ozonoff A; Jayavelu ND; Liu S; Melamed E; Milliren CE; Qi J; Geng LN; McComsey GA; Cairns CB; Baden LR
• Heightened expression of type I interferon signaling genes in CD4+ T cells from acutely HIV-1-infected women is associated with lower viral loads.
  Front Immunol Volume: 15 Page(s): 1507530
  01/01/2024 Authors: El-Badry E; Chen L; Ghneim K; Li Z; Brooks K; Rhodes J; Sekaly R; Kilembe W; Allen S; Wu H
• Corrigendum to "Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: results from the IMPACC study" [eBioMedicine 83 (2022) 104208].
  EBioMedicine Volume: 98 Page(s): 104860
  12/01/2023 Authors: Ozonoff A; Schaenman J; Jayavelu ND; Milliren CE; Calfee CS; Cairns CB; Kraft M; Baden LR; Shaw AC; Krammer F
• Integrated longitudinal multi-omics study identifies immune programs associated with COVID-19 severity and mortality in 1152 hospitalized participants.
  bioRxiv
  11/06/2023 Authors: Gygi JP; Maguire C; Patel RK; Shinde P; Konstorum A; Shannon CP; Xu L; Hoch A; Jayavelu ND; Network I
• Relationship of Heterologous Virus Responses and Outcomes in Hospitalized COVID-19 Patients.
  J Immunol Volume: 211 Page(s): 1224 - 1231
  10/15/2023 Authors: Rosenberg-Hasson Y; Holmes TH; Diray-Arce J; Chen J; Kellogg R; Snyder M; Becker PM; Ozonoff A; Rouphael N; Reed EF
• Regulation of Immune Homeostasis, Inflammation, and HIV Persistence by the Microbiome, Short-Chain Fatty Acids, and Bile Acids.
  Annu Rev Virol Volume: 10 Page(s): 397 - 422
  09/29/2023 Authors: Enriquez AB; Ten Caten F; Ghneim K; Sekaly R-P; Sharma AA
• Selective loss of CD107a TIGIT+ memory HIV-1-specific CD8+ T cells in PLWH over a decade of ART.
  Elife Volume: 12
  09/19/2023 Authors: Blanch-Lombarte O; Ouchi D; Jimenez-Moyano E; Carabelli J; Marin MA; Pea R; Pelletier A; Talla A; Sharma A; Dalmau J
• Schistosoma mansoni infection alters the host pre-vaccination environment resulting in blunted Hepatitis B vaccination immune responses.
  PLoS Negl Trop Dis Volume: 17 Page(s): e0011089
  07/01/2023 Authors: Muir R; Metcalf T; Fourati S; Bartsch Y; Kyosiimire-Lugemwa J; Canderan G; Alter G; Muyanja E; Okech B; Namatovu T
• Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients.
  Cell Rep Med Volume: 4 Page(s): 101079
  06/20/2023 Authors: Diray-Arce J; Fourati S; Doni Jayavelu N; Patel R; Maguire C; Chang AC; Dandekar R; Qi J; Lee BH; van Zalm P
• Carbohydrate ligand engagement with CD11b enhances differentiation of tumor-associated myeloid cells for immunotherapy of solid cancers.
  J Immunother Cancer Volume: 11
  06/01/2023 Authors: Roche V; Sandoval V; Wolford C; Senders Z; Kim JA; Ribeiro SP; Huang AY; Sekaly R-P; Lyons J; Zhang M
• CD8+ Tcells promote HIV latency by remodeling CD4+ Tcell metabolism to enhance their survival, quiescence, and stemness.
  Immunity Volume: 56 Page(s): 1132 - 1147.e6
  05/09/2023 Authors: Mutascio S; Mota T; Franchitti L; Sharma AA; Willemse A; Bergstresser SN; Wang H; Statzu M; Tharp GK; Weiler J
• TREM2+ and interstitial-like macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques.
  Nat Commun Volume: 14 Page(s): 1914
  04/06/2023 Authors: Upadhyay AA; Viox EG; Hoang TN; Boddapati AK; Pino M; Lee MY-H; Corry J; Strongin Z; Cowan DA; Beagle EN
• Schistosoma mansoni infection alters the host pre-vaccination environment resulting in blunted Hepatitis B vaccination immune responses.
  medRxiv
  02/26/2023 Authors: Muir R; Metcalf T; Fourati S; Bartsch Y; Lugemwa JK; Canderan G; Alter G; Muyanja E; Okech B; Namatovu T
• HIV vaccine candidate efficacy in female macaques mediated by cAMP-dependent efferocytosis and V2-specific ADCC.
  Nat Commun Volume: 14 Page(s): 575
  02/02/2023 Authors: Bissa M; Kim S; Galli V; Fourati S; Sarkis S; Arakelyan A; de Castro IS; Rahman MA; Fujiwara S; Vaccari M
• Pan-vaccine analysis reveals innate immune endotypes predictive of antibody responses to vaccination.
  Nat Immunol Volume: 23 Page(s): 1777 - 1787
  12/01/2022 Authors: Fourati S; Tomalin LE; Mul MP; Chawla DG; Gerritsen B; Rychkov D; Henrich E; Miller HER; Hagan T; Diray-Arce J
• Transcriptional atlas of the human immune response to 13 vaccines reveals a common predictor of vaccine-induced antibody responses.
  Nat Immunol Volume: 23 Page(s): 1788 - 1798
  12/01/2022 Authors: Hagan T; Gerritsen B; Tomalin LE; Fourati S; Mul MP; Chawla DG; Rychkov D; Henrich E; Miller HER; Diray-Arce J
• The Immune Signatures data resource, a compendium of systems vaccinology datasets.
  Sci Data Volume: 9 Page(s): 635
  10/20/2022 Authors: Diray-Arce J; Miller HER; Henrich E; Gerritsen B; Mul MP; Fourati S; Gygi J; Hagan T; Tomalin L; Rychkov D
• Innate antiviral immunity: how prior exposures can guide future responses.
  Trends Immunol Volume: 43 Page(s): 696 - 705
  09/01/2022 Authors: Tomalka JA; Suthar MS; Diamond MS; Sekaly RP
• Phenotypes of disease severity in a cohort of hospitalized COVID-19 patients: Results from the IMPACC study.
  EBioMedicine Volume: 83 Page(s): 104208
  09/01/2022 Authors: Ozonoff A; Schaenman J; Jayavelu ND; Milliren CE; Calfee CS; Cairns CB; Kraft M; Baden LR; Shaw AC; Krammer F
• Targeted Marrow Irradiation Intensification of Reduced-Intensity Fludarabine/Busulfan Conditioning for Allogeneic Hematopoietic Stem Cell Transplantation.
  Transplant Cell Ther Volume: 28 Page(s): 370.e1 - 370.e10
  07/01/2022 Authors: Ali N; Sharma AA; de Rezende ACP; Otegbeye F; Latif BM; Kerbauy MN; Cooper BW; Sanchez G; Metheny L; Bal SK
• Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies.
  Open Forum Infect Dis Volume: 9 Page(s): ofac171
  06/01/2022 Authors: Figueiredo JC; Hirsch FR; Kushi LH; Nembhard WN; Crawford JM; Mantis N; Finster L; Merin NM; Merchant A; Reckamp KL
• Gut-derived bacterial toxins impair memory CD4+ T cell mitochondrial function in HIV-1 infection.
  J Clin Invest Volume: 132
  05/02/2022 Authors: Ferrari B; Da Silva AC; Liu KH; Saidakova EV; Korolevskaya LB; Shmagel KV; Shive C; Pacheco Sanchez G; Retuerto M; Sharma AA
• Lymph node CXCR5+ NK cells associate with control of chronic SHIV infection.
  JCI Insight Volume: 7
  04/22/2022 Authors: Rahman SA; Billingsley JM; Sharma AA; Styles TM; Govindaraj S; Shanmugasundaram U; Babu H; Riberio SP; Ali SA; Tharp GK
• Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy.
  J Clin Invest Volume: 132
  04/15/2022 Authors: Harper J; Ribeiro SP; Chan CN; Aid M; Deleage C; Micci L; Pino M; Cervasi B; Raghunathan G; Rimmer E
• IFN- blockade during ART-treated SIV infection lowers tissue vDNA, rescues immune function, and improves overall health.
  JCI Insight Volume: 7
  03/08/2022 Authors: Swainson LA; Sharma AA; Ghneim K; Ribeiro SP; Wilkinson P; Dunham RM; Albright RG; Wong S; Estes JD; Piatak M
• Immune mechanisms in cancer patients that lead to poor outcomes of SARS-CoV-2 infection.
  Transl Res Volume: 241 Page(s): 83 - 95
  03/01/2022 Authors: Latif MB; Shukla S; Del Rio Estrada PM; Ribeiro SP; Sekaly RP; Sharma AA
• Cocaethylene, simultaneous alcohol and cocaine use, and liver fibrosis in people living with and without HIV.
  Drug Alcohol Depend Volume: 232 Page(s): 109273
  03/01/2022 Authors: Tamargo JA; Sherman KE; Skaly R-P; Bordi R; Schlatzer D; Lai S; Khalsa JH; Mandler RN; Ehman RL; Baum MK
• Fighting the SARS-CoV-2 pandemic requires a global approach to understanding the heterogeneity of vaccine responses.
  Nat Immunol Volume: 23 Page(s): 360 - 370
  03/01/2022 Authors: Tomalka JA; Suthar MS; Deeks SG; Sekaly RP
• Translating known drivers of COVID-19 disease severity to design better SARS-CoV-2 vaccines.
  Curr Opin Virol Volume: 52 Page(s): 89 - 101
  02/01/2022 Authors: Pelletier AN; Sekaly RP; Tomalka JA
• Induction of thymic atrophy and loss of thymic output by type-I interferons during chronic viral infection.
  Virology Volume: 567 Page(s): 77 - 86
  02/01/2022 Authors: Dmoulins T; Baron M-L; Gauchat D; Kettaf N; Reed SJ; Charpentier T; Kalinke U; Lamarre A; Ahmed R; Skaly R-P
• Pembrolizumab induces HIV latency reversal in people living with HIV and cancer on antiretroviral therapy.
  Sci Transl Med Volume: 14 Page(s): eabl3836
  01/26/2022 Authors: Uldrick TS; Adams SV; Fromentin R; Roche M; Fling SP; Gonalves PH; Lurain K; Ramaswami R; Wang C-CJ; Gorelick RJ
• Randomized Trial of Ruxolitinib in Antiretroviral-Treated Adults With Human Immunodeficiency Virus.
  Clin Infect Dis Volume: 74 Page(s): 95 - 104
  01/07/2022 Authors: Marconi VC; Moser C; Gavegnano C; Deeks SG; Lederman MM; Overton ET; Tsibris A; Hunt PW; Kantor A; Sekaly R-P
• Cocaine use associated gut permeability and microbial translocation in people living with HIV in the Miami Adult Study on HIV (MASH) cohort.
  PLoS One Volume: 17 Page(s): e0275675
  01/01/2022 Authors: Hernandez J; Tamargo JA; Sales Martinez S; Martin HR; Campa A; Skaly R-P; Bordi R; Sherman KE; Rouster SD; Meeds HL
• Chronic Alcohol Exposure Among People Living with HIV Is Associated with Innate Immune Activation and Alterations in Monocyte Phenotype and Plasma Cytokine Profile.
  Front Immunol Volume: 13 Page(s): 867937
  01/01/2022 Authors: Underwood ML; Park B; Uebelhoer LS; Gu G; Kunkel LE; Korthuis PT; Cook RR; Sekaly RP; Ribeiro SP; Lancioni CL
• Pre-vaccination frequency of circulatory Tfh is associated with robust immune response to TV003 dengue vaccine.
  PLoS Pathog Volume: 18 Page(s): e1009903
  01/01/2022 Authors: Izmirly AM; Pelletier A-N; Connors J; Taramangalam B; Alturki SO; Gordon EA; Alturki SO; Mell JC; Swaminathan G; Karthik V
• Multiple site place-of-care manufactured anti-CD19 CAR-T cells induce high remission rates in B-cell malignancy patients.
  Nat Commun Volume: 12 Page(s): 7200
  12/10/2021 Authors: Maschan M; Caimi PF; Reese-Koc J; Sanchez GP; Sharma AA; Molostova O; Shelikhova L; Pershin D; Stepanov A; Muzalevskii Y
• Implications of a highly divergent dengue virus strain for cross-neutralization, protection, and vaccine immunity.
  Cell Host Microbe Volume: 29 Page(s): 1634 - 1648.e5
  11/10/2021 Authors: Chen RE; Smith BK; Errico JM; Gordon DN; Winkler ES; VanBlargan LA; Desai C; Handley SA; Dowd KA; Amaro-Carambot E
• TREM2+ and interstitial macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques.
  bioRxiv
  10/05/2021 Authors: Upadhyay AA; Hoang TN; Pino M; Boddapati AK; Viox EG; Lee MYH; Corry J; Strongin Z; Cowan DA; Beagle EN
• The transcription factor CREB1 is a mechanistic driver of immunogenicity and reduced HIV-1 acquisition following ALVAC vaccination.
  Nat Immunol Volume: 22 Page(s): 1294 - 1305
  10/01/2021 Authors: Tomalka JA; Pelletier AN; Fourati S; Latif MB; Sharma A; Furr K; Carlson K; Lifton M; Gonzalez A; Wilkinson P
• Single cell RNA sequencing of AML initiating cells reveals RNA-based evolution during disease progression.
  Leukemia Volume: 35 Page(s): 2799 - 2812
  10/01/2021 Authors: Stetson LC; Balasubramanian D; Ribeiro SP; Stefan T; Gupta K; Xu X; Fourati S; Roe A; Jackson Z; Schauner R
• TCA cycle remodeling drives proinflammatory signaling in humans with pulmonary tuberculosis.
  PLoS Pathog Volume: 17 Page(s): e1009941
  09/01/2021 Authors: Collins JM; Jones DP; Sharma A; Khadka M; Liu KH; Kempker RR; Prideaux B; Maner-Smith K; Tukvadze N; Shah NS
• Looking for pathways related to COVID-19: confirmation of pathogenic mechanisms by SARS-CoV-2-host interactome.
  Cell Death Dis Volume: 12 Page(s): 788
  08/12/2021 Authors: Messina F; Giombini E; Montaldo C; Sharma AA; Zoccoli A; Sekaly R-P; Locatelli F; Zumla A; Maeurer M; Capobianchi MR
• Immunophenotyping assessment in a COVID-19 cohort (IMPACC): A prospective longitudinal study.
  Sci Immunol Volume: 6
  08/10/2021 Authors: IMPACC Manuscript Writing Team; IMPACC Network Steering Committee
• Increased homeostatic cytokines and stability of HIV-infected memory CD4 T-cells identify individuals with suboptimal CD4 T-cell recovery on-ART.
  PLoS Pathog Volume: 17 Page(s): e1009825
  08/01/2021 Authors: Pino M; Pereira Ribeiro S; Pagliuzza A; Ghneim K; Khan A; Ryan E; Harper JL; King CT; Welbourn S; Micci L
• Translocated microbiome composition determines immunological outcome in treated HIV infection.
  Cell Volume: 184 Page(s): 3899 - 3914.e16
  07/22/2021 Authors: Nganou-Makamdop K; Talla A; Sharma AA; Darko S; Ransier A; Laboune F; Chipman JG; Beilman GJ; Hoskuldsson T; Fourati S
• A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates.
  Sci Immunol Volume: 6
  07/15/2021 Authors: Pino M; Abid T; Pereira Ribeiro S; Edara VV; Floyd K; Smith JC; Latif MB; Pacheco-Sanchez G; Dutta D; Wang S
• Dual IL-10 and PD-1 blockade in SIVmac239 infected macaques promotes sustained virologic control in absence of ART
  Volume: 24 Page(s): 68 - 69
  07/01/2021 Authors: Strongin Z; Ribeiro SP; Hoang TN; Nguyen K; Harper J; Estes JD; Micci L; Lifson JD; Howell BJ; Gorman D
• Interleukin-15 response signature predicts RhCMV/SIV vaccine efficacy.
  PLoS Pathog Volume: 17 Page(s): e1009278
  07/01/2021 Authors: Barrens F; Hansen SG; Law L; Driscoll C; Green RR; Smith E; Chang J; Golez I; Urion T; Peng X
• "Go", "No Go," or "Where to Go"; does microbiota dictate T cell exhaustion, programming, and HIV persistence?
  Curr Opin HIV AIDS Volume: 16 Page(s): 215 - 222
  07/01/2021 Authors: Shukla S; Kumari S; Bal SK; Monaco DC; Ribeiro SP; Sekaly R-P; Sharma AA
• Nonstructured Treatment Interruptions Are Associated With Higher Human Immunodeficiency Virus Reservoir Size Measured by Intact Proviral DNA Assay in People Who Inject Drugs.
  J Infect Dis Volume: 223 Page(s): 1905 - 1913
  06/04/2021 Authors: Kirk GD; Astemborski J; Mehta SH; Ritter KD; Laird GM; Bordi R; Sekaly R; Siliciano JD; Siliciano RF
• Acquisition of optimal TFH cell function is defined by specific molecular, positional, and TCR dynamic signatures.
  Proc Natl Acad Sci U S A Volume: 118
  05/04/2021 Authors: Padhan K; Moysi E; Noto A; Chassiakos A; Ghneim K; Perra MM; Shah S; Papaioannou V; Fabozzi G; Ambrozak DR
• Multi-omics analyses reveal that HIV-1 alters CD4+ T cell immunometabolism to fuel virus replication.
  Nat Immunol Volume: 22 Page(s): 423 - 433
  04/01/2021 Authors: Guo H; Wang Q; Ghneim K; Wang L; Rampanelli E; Holley-Guthrie E; Cheng L; Garrido C; Margolis DM; Eller LA
• NLRP3 inflammasome induces CD4+ T cell loss in chronically HIV-1-infected patients.
  J Clin Invest Volume: 131
  03/15/2021 Authors: Zhang C; Song J-W; Huang H-H; Fan X; Huang L; Deng J-N; Tu B; Wang K; Li J; Zhou M-J
• TCF-1 regulates HIV-specific CD8+ T cell expansion capacity.
  JCI Insight Volume: 6
  02/08/2021 Authors: Rutishauser RL; Deguit CDT; Hiatt J; Blaeschke F; Roth TL; Wang L; Raymond KA; Starke CE; Mudd JC; Chen W
• Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
  Cell Volume: 184 Page(s): 460 - 475.e21
  01/21/2021 Authors: Hoang TN; Pino M; Boddapati AK; Viox EG; Starke CE; Upadhyay AA; Gumber S; Nekorchuk M; Busman-Sahay K; Strongin Z
• Is France Once Again Looking for a Scapegoat?
  Pathog Immun Volume: 6 Page(s): 149 - 152
  01/01/2021 Authors: Lederman MM; Flier JS; Hale P; Haase AT; Powderly W; Reiss P; Silvestri G; Sekaly RP; Paiardini M; Weissman D
• Prophylactic Tocilizumab Prior to Anti-CD19 CAR-T Cell Therapy for Non-Hodgkin Lymphoma.
  Front Immunol Volume: 12 Page(s): 745320
  01/01/2021 Authors: Caimi PF; Pacheco Sanchez G; Sharma A; Otegbeye F; Ahmed N; Rojas P; Patel S; Kleinsorge Block S; Schiavone J; Zamborsky K
• Neonatal T Helper 17 Responses Are Skewed Towards an Immunoregulatory Interleukin-22 Phenotype.
  Front Immunol Volume: 12 Page(s): 655027
  01/01/2021 Authors: Razzaghian HR; Sharafian Z; Sharma AA; Boyce GK; Lee K; Da Silva R; Orban PC; Sekaly R-P; Ross CJ; Lavoie PM
• Transcriptional and Immunologic Correlates of Response to Pandemic Influenza Vaccine in Aviremic, HIV-Infected Children.
  Front Immunol Volume: 12 Page(s): 639358
  01/01/2021 Authors: de Armas LR; George V; Filali-Mouhim A; Steel C; Parmigiani A; Cunningham CK; Weinberg A; Trautmann L; Sekaly R-P; Cameron MJ
• HLA polymorphism and tapasin independence influence outcomes of HIV and dengue virus infection.
  Proc Natl Acad Sci U S A Volume: 117 Page(s): 31570 - 31572
  12/15/2020 Authors: Di Pucchio T; Sekaly R-P
• Passive Transfer of Vaccine-Elicited Antibodies Protects against SIV in Rhesus Macaques.
  Cell Volume: 183 Page(s): 185 - 196.e14
  10/01/2020 Authors: Alter G; Yu W-H; Chandrashekar A; Borducchi EN; Ghneim K; Sharma A; Nedellec R; McKenney KR; Linde C; Broge T
• Baricitinib treatment resolves lower airway inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
  bioRxiv
  09/16/2020 Authors: Hoang TN; Pino M; Boddapati AK; Viox EG; Starke CE; Upadhyay AA; Gumber S; Busman-Sahay K; Strongin Z; Harper JL
• Intestinal Stem Cell Niche Defects Result in Impaired 3D Organoid Formation in Mouse Models of Crohn's Disease-like Ileitis.
  Stem Cell Reports Volume: 15 Page(s): 389 - 407
  08/11/2020 Authors: Butt LF; Pelletier A; More SK; Zhao N; Osme A; Hager CL; Ghannoum MA; Sekaly R-P; Cominelli F; Dave M
• Fc-mediated effector function contributes to the in vivo antiviral effect of an HIV neutralizing antibody.
  Proc Natl Acad Sci U S A Volume: 117 Page(s): 18754 - 18763
  08/04/2020 Authors: Asokan M; Dias J; Liu C; Maximova A; Ernste K; Pegu A; McKee K; Shi W; Chen X; Almasri C
• Decreased Enteric Bacterial Composition and Diversity in South American Crohn's Disease Vary With the Choice of Treatment Strategy and Time Since Diagnosis.
  J Crohns Colitis Volume: 14 Page(s): 791 - 800
  07/09/2020 Authors: Cruz-Lebrn A; D'argenio Garcia L; Talla A; Joussef-Pia S; Quiones-Mateu ME; Skaly R-P; de Carvalho KIL; Levine AD
• Beta cell-specific CD8+ T cells maintain stem cell memory-associated epigenetic programs during type 1 diabetes.
  Nat Immunol Volume: 21 Page(s): 578 - 587
  05/01/2020 Authors: Abdelsamed HA; Zebley CC; Nguyen H; Rutishauser RL; Fan Y; Ghoneim HE; Crawford JC; Alfei F; Alli S; Ribeiro SP
• Characterization of a novel dengue virus strain and its implication for vaccine development
  Volume: 204
  05/01/2020 Authors: Chen RE; Errico JM; Gordon D; Dowd KA; Cardosa MJ; Sariol CA; Kailas EG; Sekaly R-P; Vasilakis N; Pierson T
• Engagement of monocytes, NK cells, and CD4+ Th1 cells by ALVAC-SIV vaccination results in a decreased risk of SIVmac251 vaginal acquisition.
  PLoS Pathog Volume: 16 Page(s): e1008377
  03/01/2020 Authors: Gorini G; Fourati S; Vaccari M; Rahman MA; Gordon SN; Brown DR; Law L; Chang J; Green R; Barrens F
• Combination Immune Checkpoint Blockade to Reverse HIV Latency.
  J Immunol Volume: 204 Page(s): 1242 - 1254
  03/01/2020 Authors: Van der Sluis RM; Kumar NA; Pascoe RD; Zerbato JM; Evans VA; Dantanarayana AI; Anderson JL; Skaly RP; Fromentin R; Chomont N
• Myeloid Cells Enriched for a Dendritic Cell Population From People Living With HIV Have Altered Gene Expression Not Restored by Antiretroviral Therapy.
  Front Immunol Volume: 11 Page(s): 261
  01/01/2020 Authors: Murray SM; Zhang Y; Douek DC; Sekaly RP
• Automated Manufacture of Autologous CD19 CAR-T Cells for Treatment of Non-hodgkin Lymphoma.
  Front Immunol Volume: 11 Page(s): 1941
  01/01/2020 Authors: Jackson Z; Roe A; Sharma AA; Lopes FBTP; Talla A; Kleinsorge-Block S; Zamborsky K; Schiavone J; Manjappa S; Schauner R
• Anisocytosis is Associated With Short-Term Mortality in COVID-19 and May Reflect Proinflammatory Signature in Uninfected Ambulatory Adults.
  Pathog Immun Volume: 5 Page(s): 312 - 326
  01/01/2020 Authors: Hornick A; Tashtish N; Osnard M; Shah B; Bradigan A; Albar Z; Tomalka J; Dalton J; Sharma A; Sekaly RP
• Differentiation into an Effector Memory Phenotype Potentiates HIV-1 Latency Reversal in CD4+ T Cells.
  J Virol Volume: 93
  12/15/2019 Authors: Kulpa DA; Talla A; Brehm JH; Ribeiro SP; Yuan S; Bebin-Blackwell A-G; Miller M; Barnard R; Deeks SG; Hazuda D
• Membrane bound IL-21 based NK cell feeder cells drive robust expansion and metabolic activation of NK cells.
  Sci Rep Volume: 9 Page(s): 14916
  10/17/2019 Authors: Ojo EO; Sharma AA; Liu R; Moreton S; Checkley-Luttge M-A; Gupta K; Lee G; Lee DA; Otegbeye F; Sekaly R-P
• A vaccine-induced gene expression signature correlates with protection against SIV and HIV in multiple trials.
  Sci Transl Med Volume: 11
  08/28/2019 Authors: Ehrenberg PK; Shangguan S; Issac B; Alter G; Geretz A; Izumi T; Bryant C; Eller MA; Wegmann F; Apps R
• Gastrointestinal Microbiome and Mycobiome Changes during Autologous Transplantation for Multiple Myeloma: Results of a Prospective Pilot Study.
  Biol Blood Marrow Transplant Volume: 25 Page(s): 1511 - 1519
  08/01/2019 Authors: El Jurdi N; Filali-Mouhim A; Salem I; Retuerto M; Dambrosio NM; Baer L; Lazarus HM; Caimi P; Cooper B; Tomlinson B
• Phase 1 trial of anti-CD19 chimeric antigen receptor T (CAR-T) cells with tumor necrosis alfa receptor superfamily 19 (TNFRSFI9) transmembrane domain.
  Volume: 37
  05/20/2019 Authors: Caimi PF; Reese J; Otegbeye F; Schneider D; Chamoun K; Boughan KM; Cooper BW; Galloway E; Gallogly M; Kruger W
• STEM CELL-DERIVED 3D ORGANOIDS RECAPITULATE FEATURES OF CROHN'S DISEASE
  Volume: 156 Page(s): S1 - S1
  05/01/2019 Authors: Butto L; Pelletier A; Zhao N; Osme A; Hager C; Ghannoum M; Sekaly RP; Cominelli F; Dave M
• Transplant Outcomes and Toxicities Are Associated with Changes in Relative Abundance, Diversity and Richness of the Oral and Gastrointestinal Microbiome during Autologous Transplantation for Multiple Myeloma: Results of a Prospective Pilot Study
  Volume: 25
  03/01/2019 Authors: El Jurdi N; Filali-Mouhim A; Salem I; Retuerto M; Dambrosio NM; Lazarus HM; Caimi P; Cooper B; Tomlinson B; Metheny L
• Integrated systems approach defines the antiviral pathways conferring protection by the RV144 HIV vaccine.
  Nat Commun Volume: 10 Page(s): 863
  02/20/2019 Authors: Fourati S; Ribeiro SP; Blasco Tavares Pereira Lopes F; Talla A; Lefebvre F; Cameron M; Kaewkungwal J; Pitisuttithum P; Nitayaphan S; Rerks-Ngarm S
• PD-1 blockade potentiates HIV latency reversal ex vivo in CD4+ T cells from ART-suppressed individuals.
  Nat Commun Volume: 10 Page(s): 814
  02/18/2019 Authors: Fromentin R; DaFonseca S; Costiniuk CT; El-Far M; Procopio FA; Hecht FM; Hoh R; Deeks SG; Hazuda DJ; Lewin SR
• MULTIPLE SIGNALING PATHWAY DEFECTS IN THE INTESTINAL STEM CELL NICHE LIKELY TRIGGER CD-LIKE ILEITIS IN SAMP1/YITFC MICE
  Volume: 25 Page(s): S61 - S61
  02/01/2019 Authors: Butto LF; Pelletier A; Zhao N; Osme A; Hager C; Ghannoum M; Sekaly R-P; Cominelli F; Dave M
• MULTIPLE SIGNALING PATHWAY DEFECTS IN THE INTESTINAL STEM CELL NICHE LIKELY TRIGGER CD-LIKE ILEITIS IN SAMP1/YITFC MICE
  Volume: 156 Page(s): S87 - S87
  02/01/2019 Authors: Butto LF; Pelletier A; Zhao N; Osme A; Hager C; Ghannoum M; Sekaly R-P; Cominelli F; Dave M
• Myeloid Cell Crosstalk Regulates the Efficacy of the DNA/ALVAC/gp120 HIV Vaccine Candidate.
  Front Immunol Volume: 10 Page(s): 1072
  01/01/2019 Authors: Vaccari M; Fourati S; Brown DR; Silva de Castro I; Bissa M; Schifanella L; Doster MN; Foulds KE; Roederer M; Koup RA
• MALARIA SPECIFIC GENE EXPRESSION SIGNATURE IN B CELLS FROM PAPUA NEW GUINEAN CHILDREN
  Volume: 101 Page(s): 202 - 202
  01/01/2019 Authors: Dent AE; Weber G; Rosa B; Pelletier A; Embury P; Mantila D; Laman M; Kombut B; Ome-Kaius M; King CL
• Automated Generation and Phenotypic Characterization of Clinical Grade CD19 CAR-T Cells
  Volume: 132
  11/29/2018 Authors: Sharma A; Roe A; Lopes FB; Liu R; Reese J; Ribeiro SP; Sekaly R-P; de Lima M; Wald D
• Vaccine-induced Gene Signature Correlates With Protection Against Acquisition in Three Independent Vaccine Efficacy Trials Including RV144
  Volume: 34 Page(s): 18 - 18
  10/01/2018 Authors: Issac B; Ehrenberg P; Eller M; Alter G; Sekaly R; Robb M; Gramzinski R; Pau M; Schuitemaker H; Barouch D
• Programmed cell death-1 contributes to the establishment and maintenance of HIV-1 latency.
  AIDS Volume: 32 Page(s): 1491 - 1497
  07/17/2018 Authors: Evans VA; van der Sluis RM; Solomon A; Dantanarayana A; McNeil C; Garsia R; Palmer S; Fromentin R; Chomont N; Skaly R-P
• Lymphoid tissue fibrosis is associated with impaired vaccine responses.
  J Clin Invest Volume: 128 Page(s): 2763 - 2773
  07/02/2018 Authors: Kityo C; Makamdop KN; Rothenberger M; Chipman JG; Hoskuldsson T; Beilman GJ; Grzywacz B; Mugyenyi P; Ssali F; Akondy RS
• IL-10 contributes to, and is a biomarker for, viral persistence in ART-treated, SIV-infected rhesus macaques
  Volume: 21 Page(s): 96 - 96
  07/01/2018 Authors: Harper J; Ribeiro S; Pino M; Micci L; Aid M; Deleage C; Rimmer E; Ayanoglu G; Gorman D; Estes J
• HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition.
  Nat Med Volume: 24 Page(s): 847 - 856
  06/01/2018 Authors: Vaccari M; Fourati S; Gordon SN; Brown DR; Bissa M; Schifanella L; Silva de Castro I; Doster MN; Galli V; Omsland M
• Transcriptomic meta-analysis reveals signatures of chronic inflammation in the classical monocyte population
  Volume: 200
  05/01/2018 Authors: Golden J; Richardson B; Seth D; Cartwright M; Sekaly R-P; McCormick TS; Cooper KD; Cameron CM; Cameron MJ
• Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques.
  J Virol Volume: 92
  05/01/2018 Authors: Carnathan D; Lawson B; Yu J; Patel K; Billingsley JM; Tharp GK; Delmas OM; Dawoud R; Wilkinson P; Nicolette C
• The Contribution of Memory CD4+T cell subset phenotype to latency reversal efficiency
  Volume: 77 Page(s): 35 - 35
  04/01/2018 Authors: Kulpa D; Talla A; Ribeiro S; Barnard R; Hazuda D; Chomont N; Sekaly R
• Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells.
  Cell Volume: 172 Page(s): 517 - 533.e20
  01/25/2018 Authors: Gaya M; Barral P; Burbage M; Aggarwal S; Montaner B; Warren Navia A; Aid M; Tsui C; Maldonado P; Nair U
• Follicular CD4 T Helper Cells As a Major HIV Reservoir Compartment: A Molecular Perspective.
  Front Immunol Volume: 9 Page(s): 895
  01/01/2018 Authors: Aid M; Dupuy FP; Moysi E; Moir S; Haddad EK; Estes JD; Sekaly RP; Petrovas C; Ribeiro SP
• INNATE IMMUNE ACTIVATION IN HEALTHY MALARIA-IMMUNE ADULTS FROM WESTERN KENYA
  Volume: 99 Page(s): 561 - 561
  01/01/2018 Authors: Dobbs K; Fourati S; Embury P; Odada P; Rosa B; Mitreva M; Sekaly R-P; Kazura J; Dent A
• Novel mechanisms to inhibit HIV reservoir seeding using Jak inhibitors.
  PLoS Pathog Volume: 13 Page(s): e1006740
  12/01/2017 Authors: Gavegnano C; Brehm JH; Dupuy FP; Talla A; Ribeiro SP; Kulpa DA; Cameron C; Santos S; Hurwitz SJ; Marconi VC
• CTLA-4+PD-1- Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques.
  Immunity Volume: 47 Page(s): 776 - 788.e5
  10/17/2017 Authors: McGary CS; Deleage C; Harper J; Micci L; Ribeiro SP; Paganini S; Kuri-Cervantes L; Benne C; Ryan ES; Balderas R
• HDAC inhibition induces HIV-1 protein and enables immune-based clearance following latency reversal.
  JCI Insight Volume: 2
  08/17/2017 Authors: Wu G; Swanson M; Talla A; Graham D; Strizki J; Gorman D; Barnard RJ; Blair W; Sgaard OS; Tolstrup M
• Autologous transplantation induces massive immune activation without increasing the size of the latent SHIV reservoir
  Volume: 46 Page(s): 194 - 194
  08/01/2017 Authors: Peterson CW; Benne C; Polacino P; Baldessari A; Murnane RD; Hu S-L; Jerome K; Sekaly RP; Kiem H-P
• Myeloablative conditioning is dispensable for transplant-dependent HIV cure
  Volume: 20 Page(s): 52 - 52
  07/01/2017 Authors: Peterson C; Kaur J; Benne C; Polacino P; Filali-Mouhim A; Obenza W; Huang M-L; Jerome K; Hu S-L; Sekaly R
• Human memory CD8 T cell effector potential is epigenetically preserved during in vivo homeostasis.
  J Exp Med Volume: 214 Page(s): 1593 - 1606
  06/05/2017 Authors: Abdelsamed HA; Moustaki A; Fan Y; Dogra P; Ghoneim HE; Zebley CC; Triplett BM; Sekaly R-P; Youngblood B
• Vaccine-induced temporal cross-talk between myeloid cells reduces the risk of SIVmac251 acquisition
  Volume: 198
  05/01/2017 Authors: Vaccari M; Gordon SN; Fourati S; Brown D; Bissa M; Doster MN; Keele BK; Schifanella L; Lyianage N; Foulds K
• Loss of immune homeostasis dictates SHIV rebound after stem-cell transplantation.
  JCI Insight Volume: 2 Page(s): e91230
  02/23/2017 Authors: Peterson CW; Benne C; Polacino P; Kaur J; McAllister CE; Filali-Mouhim A; Obenza W; Pecor TA; Huang M-L; Baldessari A
• Maternal BCG scar is associated with increased infant proinflammatory immune responses.
  Vaccine Volume: 35 Page(s): 273 - 282
  01/05/2017 Authors: Mawa PA; Webb EL; Filali-Mouhim A; Nkurunungi G; Sekaly R-P; Lule SA; Prentice S; Nash S; Dockrell HM; Elliott AM
• The interferon paradox: can inhibiting an antiviral mechanism advance an HIV cure?
  J Clin Invest Volume: 127 Page(s): 103 - 105
  01/03/2017 Authors: Deeks SG; Odorizzi PM; Sekaly R-P
• Corrigendum: Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.
  Nat Med Volume: 22 Page(s): 1192
  10/06/2016 Authors: Vaccari M; Gordon SN; Fourati S; Schifanella L; Liyanage NPM; Cameron M; Keele BF; Shen X; Tomaras GD; Billings E
• Tn-MUC1 DC Vaccination of Rhesus Macaques and a Phase I/II Trial in Patients with Nonmetastatic Castrate-Resistant Prostate Cancer.
  Cancer Immunol Res Volume: 4 Page(s): 881 - 892
  10/01/2016 Authors: Scheid E; Major P; Bergeron A; Finn OJ; Salter RD; Eady R; Yassine-Diab B; Favre D; Peretz Y; Landry C
• Antibody-mediated protection against SHIV challenge includes systemic clearance of distal virus.
  Science Volume: 353 Page(s): 1045 - 1049
  09/02/2016 Authors: Liu J; Ghneim K; Sok D; Bosche WJ; Li Y; Chipriano E; Berkemeier B; Oswald K; Borducchi E; Cabral C
• Kynurenine Reduces Memory CD4 T-Cell Survival by Interfering with Interleukin-2 Signaling Early during HIV-1 Infection.
  J Virol Volume: 90 Page(s): 7967 - 7979
  09/01/2016 Authors: Dagenais-Lussier X; Aounallah M; Mehraj V; El-Far M; Tremblay C; Sekaly R-P; Routy J-P; van Grevenynghe J
• Effect of Anti-IL-15 Administration on T Cell and NK Cell Homeostasis in Rhesus Macaques.
  J Immunol Volume: 197 Page(s): 1183 - 1198
  08/15/2016 Authors: DeGottardi MQ; Okoye AA; Vaidya M; Talla A; Konfe AL; Reyes MD; Clock JA; Duell DM; Legasse AW; Sabnis A
• The sooner the better: innate immunity as a path toward the HIV cure.
  Curr Opin Virol Volume: 19 Page(s): 85 - 91
  08/01/2016 Authors: Tomalka J; Ghneim K; Bhattacharyya S; Aid M; Barouch DH; Sekaly RP; Ribeiro SP
• Systems biology and the quest for correlates of protection to guide the development of an HIV vaccine.
  Curr Opin Immunol Volume: 41 Page(s): 91 - 97
  08/01/2016 Authors: Kuri-Cervantes L; Fourati S; Canderan G; Sekaly R-P
• HCV RNA Activates APCs via TLR7/TLR8 While Virus Selectively Stimulates Macrophages Without Inducing Antiviral Responses.
  Sci Rep Volume: 6 Page(s): 29447
  07/07/2016 Authors: Zhang Y; El-Far M; Dupuy FP; Abdel-Hakeem MS; He Z; Procopio FA; Shi Y; Haddad EK; Ancuta P; Sekaly R-P
• CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART.
  PLoS Pathog Volume: 12 Page(s): e1005761
  07/01/2016 Authors: Fromentin R; Bakeman W; Lawani MB; Khoury G; Hartogensis W; DaFonseca S; Killian M; Epling L; Hoh R; Sinclair E
• IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection.
  J Clin Invest Volume: 126 Page(s): 2745 - 2756
  07/01/2016 Authors: Younes S-A; Freeman ML; Mudd JC; Shive CL; Reynaldi A; Panigrahi S; Estes JD; Deleage C; Lucero C; Anderson J
• Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.
  Nat Med Volume: 22 Page(s): 762 - 770
  07/01/2016 Authors: Vaccari M; Gordon SN; Fourati S; Schifanella L; Liyanage NPM; Cameron M; Keele BF; Shen X; Tomaras GD; Billings E
• Human newborn bacille Calmette-Gurin vaccination and risk of tuberculosis disease: a case-control study.
  BMC Med Volume: 14 Page(s): 76
  05/16/2016 Authors: Fletcher HA; Filali-Mouhim A; Nemes E; Hawkridge A; Keyser A; Njikan S; Hatherill M; Scriba TJ; Abel B; Kagina BM
• Sequential Infection with Common Pathogens Promotes Human-like Immune Gene Expression and Altered Vaccine Response.
  Cell Host Microbe Volume: 19 Page(s): 713 - 719
  05/11/2016 Authors: Reese TA; Bi K; Kambal A; Filali-Mouhim A; Beura LK; Brger MC; Pulendran B; Sekaly R-P; Jameson SC; Masopust D
• Normalizing the environment recapitulates adult human immune traits in laboratory mice.
  Nature Volume: 532 Page(s): 512 - 516
  04/28/2016 Authors: Beura LK; Hamilton SE; Bi K; Schenkel JM; Odumade OA; Casey KA; Thompson EA; Fraser KA; Rosato PC; Filali-Mouhim A
• Rapid Inflammasome Activation following Mucosal SIV Infection of Rhesus Monkeys.
  Cell Volume: 165 Page(s): 656 - 667
  04/21/2016 Authors: Barouch DH; Ghneim K; Bosche WJ; Li Y; Berkemeier B; Hull M; Bhattacharyya S; Cameron M; Liu J; Smith K
• A Numerically Subdominant CD8 T Cell Response to Matrix Protein of Respiratory Syncytial Virus Controls Infection with Limited Immunopathology.
  PLoS Pathog Volume: 12 Page(s): e1005486
  03/01/2016 Authors: Liu J; Haddad EK; Marceau J; Morabito KM; Rao SS; Filali-Mouhim A; Sekaly R-P; Graham BS
• Pre-vaccination inflammation and B-cell signalling predict age-related hyporesponse to hepatitis B vaccination.
  Nat Commun Volume: 7 Page(s): 10369
  01/08/2016 Authors: Fourati S; Cristescu R; Loboda A; Talla A; Filali A; Railkar R; Schaeffer AK; Favre D; Gagnon D; Peretz Y
• Mucosal Regulatory T Cells and T Helper 17 Cells in HIV-Associated Immune Activation.
  Front Immunol Volume: 7 Page(s): 228
  01/01/2016 Authors: Pandiyan P; Younes S-A; Ribeiro SP; Talla A; McDonald D; Bhaskaran N; Levine AD; Weinberg A; Sekaly RP
• A Cure for HIV Infection: "Not in My Lifetime" or "Just Around the Corner"?
  Pathog Immun Volume: 1 Page(s): 154 - 164
  01/01/2016 Authors: Lederman MM; Cannon PM; Currier JS; June CH; Kiem HP; Kuritzkes DR; Lewin SR; Margolis DM; McCune JM; Mellors JW
• Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach.
  Retrovirology Volume: 12 Page(s): 102
  12/10/2015 Authors: Cleret-Buhot A; Zhang Y; Planas D; Goulet J-P; Monteiro P; Gosselin A; Wacleche VS; Tremblay CL; Jenabian M-A; Routy J-P
• Current topics in HIV-1 pathogenesis: The emergence of deregulated immuno-metabolism in HIV-infected subjects.
  Cytokine Growth Factor Rev Volume: 26 Page(s): 603 - 613
  12/01/2015 Authors: Dagenais-Lussier X; Mouna A; Routy J-P; Tremblay C; Sekaly R-P; El-Far M; Grevenynghe JV
• A Novel Assay to Measure the Magnitude of the Inducible Viral Reservoir in HIV-infected Individuals.
  EBioMedicine Volume: 2 Page(s): 874 - 883
  08/01/2015 Authors: Procopio FA; Fromentin R; Kulpa DA; Brehm JH; Bebin A-G; Strain MC; Richman DD; O'Doherty U; Palmer S; Hecht FM
• Trancriptomics and metabolomics identify inflammatory profiles that segregate subjects with high and low inducible HIV reservoir
  Volume: 18
  07/01/2015 Authors: Ghneim K; Ahlers J; Fourati S; Shive C; Cameron M; Mukerjee P; Ghannoum M; Rodriguez B; Deeks S; Lederman M
• Beyond adjuvants: Antagonizing inflammation to enhance vaccine immunity.
  Vaccine Volume: 33 Suppl 2 Page(s): B55 - B59
  06/08/2015 Authors: Alter G; Sekaly RP
• Nef promotes evasion of human immunodeficiency virus type 1-infected cells from the CTLA-4-mediated inhibition of T-cell activation.
  J Gen Virol Volume: 96 Page(s): 1463 - 1477
  06/01/2015 Authors: El-Far M; Ancuta P; Routy J-P; Zhang Y; Bakeman W; Bordi R; DaFonseca S; Said EA; Gosselin A; Tep T-S
• IL-15 drives CD8 T cell cycling and differentiation in chronic HIV-1 infection
  Volume: 194
  05/01/2015 Authors: Younes S; Shive C; Reynaldi A; Freeman M; Panigrahi S; Estes J; Anderson J; Schacker T; Davenport M; McCune J
• Adoptive Transfer of ZFN Mediated CCR5 Modified CD4 T-cells (SB-728-T) in HIV Subjects Leads to Long Term Engraftment of HIV Resistant T Memory Stem Cells and Decrease in Size of Latent Reservoir
  Volume: 23 Page(s): S102 - S102
  05/01/2015 Authors: Zeidan J; Lee G; Fromentin R; Lalezari J; Mitsuyasu R; Wang S; Giedlin MA; Nichol G; Tang W; Chomont N
• Interleukin-1- and type I interferon-dependent enhanced immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef vaccine vector with dual deletions of type I and type II interferon-binding proteins.
  J Virol Volume: 89 Page(s): 3819 - 3832
  04/01/2015 Authors: Delaloye J; Filali-Mouhim A; Cameron MJ; Haddad EK; Harari A; Goulet J-P; Gomez CE; Perdiguero B; Esteban M; Pantaleo G
• Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow.
  J Exp Med Volume: 212 Page(s): 385 - 399
  03/09/2015 Authors: Lee J; Breton G; Oliveira TYK; Zhou YJ; Aljoufi A; Puhr S; Cameron MJ; Skaly R-P; Nussenzweig MC; Liu K
• Atorvastatin reduces T-cell activation and exhaustion among HIV-infected cART-treated suboptimal immune responders in Uganda: a randomised crossover placebo-controlled trial.
  Trop Med Int Health Volume: 20 Page(s): 380 - 390
  03/01/2015 Authors: Nakanjako D; Ssinabulya I; Nabatanzi R; Bayigga L; Kiragga A; Joloba M; Kaleebu P; Kambugu AD; Kamya MR; Sekaly R
• Transcriptional profiles reveal a stepwise developmental program of memory CD8(+) T cell differentiation.
  Vaccine Volume: 33 Page(s): 914 - 923
  02/11/2015 Authors: Roychoudhuri R; Lefebvre F; Honda M; Pan L; Ji Y; Klebanoff CA; Nichols CN; Fourati S; Hegazy AN; Goulet J-P
• IL-15 and CMV co-infection drive CD8 T-cell expansion in HIV-1 infection
  Volume: 20 Page(s): A8 - A9
  01/01/2015 Authors: Younes S-A; Freeman ML; Mudd JC; Shive CL; Reynaldi A; Panigrahi S; Estes JD; Deleage C; Lucero C; Anderson J
• Endhanced levels of Zinc Finger Nuclease CCR5 Modified CD4 cells (SB-728-T) Reduce Viral Load (VL) in HIV Subjects Treatment Interruption (TI)
  Volume: 25 Page(s): A89 - A89
  11/01/2014 Authors: Ando D; Sekaly RP
• Emergence of individual HIV-specific CD8 T cell responses during primary HIV-1 infection can determine long-term disease outcome.
  J Virol Volume: 88 Page(s): 12793 - 12801
  11/01/2014 Authors: Streeck H; Lu R; Beckwith N; Milazzo M; Liu M; Routy J-P; Little S; Jessen H; Kelleher AD; Hecht F
• Integrated Systems Biology Analysis Reveals Contrasting Role for Innate Immune Response Genes in Conferring Risk of Infection in RV144 Trial
  Volume: 30 Page(s): A15 - A16
  10/01/2014 Authors: Filali-Mouhim A; Fourati S; Lefebvre F; Thomas R; Gottardo R; Frahm N; De Rosa S; Wilkinson P; Stafova P; Sabnis A
• JAK INHIBITORS TOFACITINIB AND RUXOLITINIB EMPLOY A NOVEL MECHANISM TO INHIBIT HIV-1 REPLICATION AND PRO-HIV EVENTS IN PRIMARY RHESUS MACAQUE AND HUMAN LYMPHOCYTES AND MACROPHAGES
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 381 - 381
  10/01/2014 Authors: Gavegnano C; Montero C; Dupuy F; Brehm J; Sekaly R; Schinazi RF
• IL-1R, WNT and gamma-C Cytokine Receptor Signaling Correlate with CD4 T Cell Effector Function in Response to Anti-DEC205-HIV gag p24/polyICLC Vaccination
  Volume: 30 Page(s): A250 - A251
  10/01/2014 Authors: Ghneim K; Caskey M; Trumpfheller C; Breton G; Stafova P; Richards S; Koup R; Bailor B; Schlesinger S; Ahlers J
• Adjuvant Dependent Mucosal V2 Responses and RAS Activation in Vaccine Induced Protection from SIVmac251 Acquisition
  Volume: 30 Page(s): A64 - A65
  10/01/2014 Authors: Vaccari M; Gordon SN; Fourati S; Schifanella L; Cameron M; Keele BF; Shen X; Tomaras G; Billings E; Rao M
• Activation of HIV transcription with short-course vorinostat in HIV-infected patients on suppressive antiretroviral therapy.
  PLoS Pathog Volume: 10 Page(s): e1004473
  10/01/2014 Authors: Elliott JH; Wightman F; Solomon A; Ghneim K; Ahlers J; Cameron MJ; Smith MZ; Spelman T; McMahon J; Velayudham P
• INTERFERON-ALPHA BLOCKADE DURING SIV INFECTION OF RHESUS MACAQUES REDUCES LYMPHOCYTE ACTIVATION
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 389 - 389
  10/01/2014 Authors: Vanderford TH; Steel C; Zeidan J; Yu J; Zhang Y; Ahlers J; Nicolette C; Tcherepanova I; Cameron M; Sekaly RP
• Immune activation alters cellular and humoral responses to yellow fever 17D vaccine (vol 124, pg 3147, 2014)
  JOURNAL OF CLINICAL INVESTIGATION Volume: 124 Page(s): 4669 - 4669
  10/01/2014 Authors: Muyanja E; Ssemaganda A; Ngauv P; Cubas R; Perrin H; Srinivasan D; Canderan G; Lawson B; Kopycinski J; Graham AS
• CD80 and CD86 IgC domains are important for quaternary structure, receptor binding and co-signaling function.
  Immunol Lett Volume: 161 Page(s): 65 - 75
  09/01/2014 Authors: Girard T; Gaucher D; El-Far M; Breton G; Skaly R-P
• A randomized controlled trial of palifermin (recombinant human keratinocyte growth factor) for the treatment of inadequate CD4+ T-lymphocyte recovery in patients with HIV-1 infection on antiretroviral therapy.
  J Acquir Immune Defic Syndr Volume: 66 Page(s): 399 - 406
  08/01/2014 Authors: Jacobson JM; Wang H; Bordi R; Zheng L; Gross BH; Landay AL; Spritzler J; Routy J-P; Benson C; Aberg J
• Programmed death-1 expression on CD4 and CD8 T cells in treated and untreated HIV disease.
  AIDS Volume: 28 Page(s): 1749 - 1758
  07/31/2014 Authors: Cockerham LR; Jain V; Sinclair E; Glidden DV; Hartogenesis W; Hatano H; Hunt PW; Martin JN; Pilcher CD; Sekaly R
• Immune activation alters cellular and humoral responses to yellow fever 17D vaccine.
  J Clin Invest Volume: 124 Page(s): 3147 - 3158
  07/01/2014 Authors: Muyanja E; Ssemaganda A; Ngauv P; Cubas R; Perrin H; Srinivasan D; Canderan G; Lawson B; Kopycinski J; Graham AS
• Microarray analysis reveals novel insights into immunity to H1N1/09 influenza vaccine in aviremic HIV infected children and adolescents in IMPAACT P1088
  Volume: 192
  05/01/2014 Authors: de Armas L; George V; Steel C; Filali A; Wilkinson P; Parmigiani A; Andreansky S; Gonzalez I; Weinberg A; Cunningham C
• HIV Protected Autologous Zinc Finger Nuclease Driven CCR5 Modified CD4 T-Cells CCR5 (SB-728-T) Reduce HIV Viral Load in CCR5 Delta 32 Heterozygote Subjects During Treatment Interruption (TI): Correlates of Effect, and Effect of Cytoxan Pre-Conditioning Regimen
  Volume: 22 Page(s): S109 - S109
  05/01/2014 Authors: Zeidan J; Lelazari JP; Tang W; Lee G; Nichols G; Deeks S; Sekaly R-P; Ando D
• Quantifying and predicting the effect of exogenous interleukin-7 on CD4+ T cells in HIV-1 infection.
  PLoS Comput Biol Volume: 10 Page(s): e1003630
  05/01/2014 Authors: Thibaut R; Drylewicz J; Prague M; Lacabaratz C; Beq S; Jarne A; Croughs T; Sekaly R-P; Lederman MM; Sereti I
• MMTV superantigens coerce an unconventional topology between the TCR and MHC class II.
  J Immunol Volume: 192 Page(s): 1896 - 1906
  02/15/2014 Authors: Fortin J-S; Genve L; Gauthier C; Shoukry NH; Azar GA; Younes S; Yassine-Diab B; Skaly R-P; Fremont DH; Thibodeau J
• Infusion of ZFN CCR5 modified CD4 T-cells (SB-728-T) led to long term reconstitution of CD4 T-cells and reduction of HIV-DNA levels in HIV infected subjects on ART
  Volume: 24 Page(s): A57 - A57
  12/01/2013 Authors: Zeidan J; Lee G; Lalezari J; Mitsuyasu R; Wang S; Giedlin M; Holmes M; Tang W; Nichol G; Sekaly R-P
• Temporal effect of HLA-B*57 on viral control during primary HIV-1 infection.
  Retrovirology Volume: 10 Page(s): 139
  11/18/2013 Authors: Vaidya SA; Streeck H; Beckwith N; Ghebremichael M; Pereyra F; Kwon DS; Addo MM; Rychert J; Routy J-P; Jessen H
• CD4 reconstitution and reduction of reservoir in HIV-positive patients following a single infusion of CCR5 modified autologous CD4 T cells (SB-728-T)
  Volume: 382 Page(s): 21 - 21
  11/03/2013 Authors: Sekaly R-P; Zeidan J; Lalezari J; Mitsuyasu R; Lee G; Giedlin M; Nichol G; Tang W; Ando D; Deeks S
• Transcriptional Profiling of RV144 Participants Reveals a Gene Expression Signature that Correlates with Immunogenicity
  Volume: 29 Page(s): A173 - A174
  11/01/2013 Authors: Cameron M; Sabnis A; Lefebvre F; Gottardo R; Frahm N; De Rosa S; Wilkinson P; Michael N; Kim J; McElrath M
• Dual Deletion of Type I and Type II Interferon-Binding Proteins in NYVAC-HIV1 Env-Gag-Pol-Nef Poxvirus Vectors Markedly Improves Vector Immunogenicity
  Volume: 29 Page(s): A148 - A148
  11/01/2013 Authors: Delaloye J; Filali-Mouhim A; Cameron M; Haddad E; Harari A; Goulet J; Gomez CE; Perdiguero B; Esteban M; Pantaleo G
• Host Immune Environment Impact the Level of CD4 Central Memory Reconstitution in HIV Subjects Receiving ZFN CCR5 Modified CD4 T-Cells (SB-728-T)
  Volume: 29 Page(s): A117 - A117
  11/01/2013 Authors: Zeidan J; Lee G; Ahlers J; Lalezari J; Mitsuyasu R; Wang S; Giedlin M; Tang W; Nichol G; Cameron M
• PD-1 coinhibitory signals: the link between pathogenesis and protection.
  Semin Immunol Volume: 25 Page(s): 219 - 227
  10/31/2013 Authors: Kulpa DA; Lawani M; Cooper A; Peretz Y; Ahlers J; Skaly R-P
• MODULATION OF THE PD-1 PATHWAY TO ENHANCE VIRUS PRODUCTION AND ELIMINATION OF LATENTLY INFECTED T CELLS IN SIV-INFECTED RHESUS MACAQUES ON HIGHLY ACTIVE ANTIRETROVIRAL THERAPY (HAART)
  Volume: 42 Page(s): 260 - 260
  10/01/2013 Authors: Okoye AA; Rohankhedkar M; Konfe A; Fukazawa Y; Lum R; Park H; Axthelm IB; Legasse A; Axthelm MK; Oswald K
• A systems framework for vaccine design.
  Curr Opin Immunol Volume: 25 Page(s): 551 - 555
  10/01/2013 Authors: Mooney M; McWeeney S; Canderan G; Skaly R-P
• Programmed death-1 is a marker for abnormal distribution of naive/memory T cell subsets in HIV-1 infection.
  J Immunol Volume: 191 Page(s): 2194 - 2204
  09/01/2013 Authors: Breton G; Chomont N; Takata H; Fromentin R; Ahlers J; Filali-Mouhim A; Riou C; Boulassel M-R; Routy J-P; Yassine-Diab B
• Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells.
  J Immunol Volume: 191 Page(s): 540 - 544
  07/15/2013 Authors: Youngblood B; Noto A; Porichis F; Akondy RS; Ndhlovu ZM; Austin JW; Bordi R; Procopio FA; Miura T; Allen TM
• GenePattern flow cytometry suite.
  Source Code Biol Med Volume: 8 Page(s): 14
  07/03/2013 Authors: Spidlen J; Barsky A; Breuer K; Carr P; Nazaire M-D; Hill BA; Qian Y; Liefeld T; Reich M; Mesirov JP
• The immunological synapse: the gateway to the HIV reservoir.
  Immunol Rev Volume: 254 Page(s): 305 - 325
  07/01/2013 Authors: Kulpa DA; Brehm JH; Fromentin R; Cooper A; Cooper C; Ahlers J; Chomont N; Skaly R-P
• Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs.
  Lancet Volume: 381 Page(s): 2109 - 2117
  06/15/2013 Authors: Katlama C; Deeks SG; Autran B; Martinez-Picado J; van Lunzen J; Rouzioux C; Miller M; Vella S; Schmitz JE; Ahlers J
• Long Term CD4 Reconstitution in HIV Subjects Receiving ZFN CCR5 Modified CD4 T-Cells (SB-728-T) May Be Attributed to the Sustained Durability of the Central Memory T-Cell Subset
  Volume: 21 Page(s): S24 - S24
  06/01/2013 Authors: Lee GK; Zeidan J; Lalezari J; Mitsuyasu R; Wang S; Giedlin M; Nichol G; Tang W; Ando D; Sekaly R-P
• Interleukin-7 promotes HIV persistence during antiretroviral therapy.
  Blood Volume: 121 Page(s): 4321 - 4329
  05/23/2013 Authors: Vandergeeten C; Fromentin R; DaFonseca S; Lawani MB; Sereti I; Lederman MM; Ramgopal M; Routy J-P; Skaly R-P; Chomont N
• Systems immunogenetics of vaccines.
  Semin Immunol Volume: 25 Page(s): 124 - 129
  04/01/2013 Authors: Mooney M; McWeeney S; Skaly R-P
• Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation.
  Ann Neurol Volume: 73 Page(s): 341 - 354
  03/01/2013 Authors: Darlington PJ; Touil T; Doucet J-S; Gaucher D; Zeidan J; Gauchat D; Corsini R; Kim HJ; Duddy M; Jalili F
• Antibodies to gp120 and PD-1 expression on virus-specific CD8+ T cells in protection from simian AIDS.
  J Virol Volume: 87 Page(s): 3526 - 3537
  03/01/2013 Authors: Vaccari M; Halwani R; Patterson LJ; Boasso A; Beal J; Tryniszewska E; Hryniewicz A; Venzon D; Haddad EK; El-Far M
• Short communication: human immunodeficiency virus rebound in blood and seminal plasma following discontinuation of antiretroviral therapy.
  AIDS Res Hum Retroviruses Volume: 29 Page(s): 266 - 269
  02/01/2013 Authors: Costiniuk CT; Kovacs C; Routy J-P; Singer J; Gurunathan S; Sekaly R-P; Angel JB
• Intrinsic role of FoxO3a in the development of CD8+ T cell memory.
  J Immunol Volume: 190 Page(s): 1066 - 1075
  02/01/2013 Authors: Tzelepis F; Joseph J; Haddad EK; Maclean S; Dudani R; Agenes F; Peng SL; Sekaly R-P; Sad S
• Systems analysis of a RIG-I agonist inducing broad spectrum inhibition of virus infectivity.
  PLoS Pathog Volume: 9 Page(s): e1003298
  01/01/2013 Authors: Goulet M-L; Olagnier D; Xu Z; Paz S; Belgnaoui SM; Lafferty EI; Janelle V; Arguello M; Paquet M; Ghneim K
• Characterization of transcription factor phenotypes within antigen-specific CD4+ T cells using qualitative multiplex single-cell RT-PCR.
  PLoS One Volume: 8 Page(s): e74946
  01/01/2013 Authors: Phetsouphanh C; Xu Y; Amin J; Seddiki N; Procopio F; Sekaly RP; Zaunders JJ; Kelleher AD
• Myeloid dendritic cells induce HIV-1 latency in non-proliferating CD4+ T cells.
  PLoS Pathog Volume: 9 Page(s): e1003799
  01/01/2013 Authors: Evans VA; Kumar N; Filali A; Procopio FA; Yegorov O; Goulet J-P; Saleh S; Haddad EK; da Fonseca Pereira C; Ellenberg PC
• Residual immune dysregulation syndrome in treated HIV infection.
  Volume: 119 Page(s): 51 - 83
  01/01/2013 Authors: Lederman MM; Funderburg NT; Sekaly RP; Klatt NR; Hunt PW
• Down-regulation of CTLA-4 by HIV-1 Nef protein.
  PLoS One Volume: 8 Page(s): e54295
  01/01/2013 Authors: El-Far M; Isabelle C; Chomont N; Bourbonnire M; Fonseca S; Ancuta P; Peretz Y; Chouikh Y; Halwani R; Schwartz O
• Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.
  Nat Med Volume: 18 Page(s): 1673 - 1681
  11/01/2012 Authors: Fukazawa Y; Park H; Cameron MJ; Lefebvre F; Lum R; Coombes N; Mahyari E; Hagen SI; Bae JY; Reyes MD
• Profound metabolic, functional, and cytolytic differences characterize HIV-specific CD8 T cells in primary and chronic HIV infection.
  Blood Volume: 120 Page(s): 3466 - 3477
  10/25/2012 Authors: Trautmann L; Mbitikon-Kobo F-M; Goulet J-P; Peretz Y; Shi Y; Van Grevenynghe J; Procopio FA; Boulassel MR; Routy J-P; Chomont N
• Characterization of early gene expression profile in the blood of macaques immunized a Thai trail-like vaccine
  Volume: 15 Page(s): 30 - 30
  10/01/2012 Authors: Vaccari M; Cameron M; Liyanage N; Pegu P; Gordon S; Doster M; Sekaly R-P; Franchini G
• Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C
  Volume: 9
  09/13/2012 Authors: Gomez C; Perdiguero B; Jimenez V; Filali-Mouhim A; Ghneim K; Haddad E; Quakkerlaar E; Delaloye J; Harari A; Roger T
• Effects of recombinant human interleukin 7 on T-cell recovery and thymic output in HIV-infected patients receiving antiretroviral therapy: results of a phase I/IIa randomized, placebo-controlled, multicenter study.
  Clin Infect Dis Volume: 55 Page(s): 291 - 300
  07/01/2012 Authors: Lvy Y; Sereti I; Tambussi G; Routy JP; Lelivre JD; Delfraissy JF; Molina JM; Fischl M; Goujard C; Rodriguez B
• A conserved polylysine motif in CD86 cytoplasmic tail is necessary for cytoskeletal association and effective co-stimulation.
  Biochem Biophys Res Commun Volume: 423 Page(s): 301 - 307
  06/29/2012 Authors: Girard T; El-Far M; Gaucher D; Acuto O; Beaul G; Michel F; Mourad W; Skaly R-P
• Type I IFN induced by adenovirus serotypes 28 and 35 has multiple effects on T cell immunogenicity.
  J Immunol Volume: 188 Page(s): 6109 - 6118
  06/15/2012 Authors: Johnson MJ; Petrovas C; Yamamoto T; Lindsay RWB; Lor K; Gall JGD; Gostick E; Lefebvre F; Cameron MJ; Price DA
• Intrinsic role of FoxO3a in the contraction of CD8+T cell response
  Volume: 188
  05/01/2012 Authors: Sad S; Haddad E; Peng S; Sekaly R; Tzelepis F
• Valproic acid in association with highly active antiretroviral therapy for reducing systemic HIV-1 reservoirs: results from a multicentre randomized clinical study.
  HIV Med Volume: 13 Page(s): 291 - 296
  05/01/2012 Authors: Routy JP; Tremblay CL; Angel JB; Trottier B; Rouleau D; Baril JG; Harris M; Trottier S; Singer J; Chomont N
• Clonotype and repertoire changes drive the functional improvement of HIV-specific CD8 T cell populations under conditions of limited antigenic stimulation.
  J Immunol Volume: 188 Page(s): 1156 - 1167
  02/01/2012 Authors: Janbazian L; Price DA; Canderan G; Filali-Mouhim A; Asher TE; Ambrozak DR; Scheinberg P; Boulassel MR; Routy J-P; Koup RA
• Ex vivo measurement of the cytotoxic capacity of human primary antigen-specific CD8 T cells.
  J Immunol Methods Volume: 375 Page(s): 252 - 257
  01/31/2012 Authors: Mbitikon-Kobo F-M; Bonneville M; Sekaly R-P; Trautmann L
• Design and implementation of a randomized crossover study of valproic acid and antiretroviral therapy to reduce the HIV reservoir.
  HIV Clin Trials Volume: 13 Page(s): 301 - 307
  01/01/2012 Authors: Routy JP; Angel JB; Spaans JN; Trottier B; Rouleau D; Baril JG; Harris M; Trottier S; Singer J; Chomont N
• CD160 and PD-1 co-expression on HIV-specific CD8 T cells defines a subset with advanced dysfunction.
  PLoS Pathog Volume: 8 Page(s): e1002840
  01/01/2012 Authors: Peretz Y; He Z; Shi Y; Yassine-Diab B; Goulet J-P; Bordi R; Filali-Mouhim A; Loubert J-B; El-Far M; Dupuy FP
• Foxo3a: an integrator of immune dysfunction during HIV infection.
  Cytokine Growth Factor Rev Volume: 23 Page(s): 215 - 221
  01/01/2012 Authors: van Grevenynghe J; Cubas RA; DaFonseca S; Metcalf T; Tremblay CL; Trautmann L; Sekaly R-P; Schatzle J; Haddad EK
• Autologous HIV-1 clade-B Nef peptides elicit increased frequency, breadth and function of CD8+ T-cells compared to consensus peptides.
  PLoS One Volume: 7 Page(s): e49562
  01/01/2012 Authors: Doroudchi M; Yegorov O; Baumgartner T; Kernaleguen A-E; Breton G; Ndongala ML; Boulassel M-R; Routy J-P; Bernard NF; Skaly R-P
• CD4 T cell nadir independently predicts the magnitude of the HIV reservoir after prolonged suppressive antiretroviral therapy.
  J Clin Virol Volume: 53 Page(s): 29 - 32
  01/01/2012 Authors: Boulassel M-R; Chomont N; Pai NP; Gilmore N; Skaly R-P; Routy J-P
• Dissecting the HIV-specific immune response: a systems biology approach.
  Curr Opin HIV AIDS Volume: 7 Page(s): 17 - 23
  01/01/2012 Authors: Peretz Y; Cameron C; Skaly R-P
• Microarray analysis of HIV resistant female sex workers reveal a gene expression signature pattern reminiscent of a lowered immune activation state.
  PLoS One Volume: 7 Page(s): e30048
  01/01/2012 Authors: Songok EM; Luo M; Liang B; Mclaren P; Kaefer N; Apidi W; Boucher G; Kimani J; Wachihi C; Sekaly R
• Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection.
  PLoS One Volume: 7 Page(s): e33948
  01/01/2012 Authors: Ananworanich J; Schuetz A; Vandergeeten C; Sereti I; de Souza M; Rerknimitr R; Dewar R; Marovich M; van Griensven F; Sekaly R
• Systems analysis of MVA-C induced immune response reveals its significance as a vaccine candidate against HIV/AIDS of clade C.
  PLoS One Volume: 7 Page(s): e35485
  01/01/2012 Authors: Gmez CE; Perdiguero B; Jimnez V; Filali-Mouhim A; Ghneim K; Haddad EK; Quakkelaar ED; Delaloye J; Harari A; Roger T
• An open-ended plea for the development of a global database of HIV vaccine responses.
  Curr Opin HIV AIDS Volume: 7 Page(s): 10 - 16
  01/01/2012 Authors: Wilkinson P; Filali-Mouhim A; Li S; Ahlers J; Schatzle J; Pulendran B; Sekaly R-P; Cameron MJ
• Systems biology in understanding HIV pathogenesis and guiding vaccine development.
  Curr Opin HIV AIDS Volume: 7 Page(s): 1 - 3
  01/01/2012 Authors: Sekaly R; Pulendran B
• Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans.
  J Exp Med Volume: 208 Page(s): 2357 - 2366
  11/21/2011 Authors: Caskey M; Lefebvre F; Filali-Mouhim A; Cameron MJ; Goulet J-P; Haddad EK; Breton G; Trumpfheller C; Pollak S; Shimeliovich I
• Loss of memory B cells during chronic HIV infection is driven by Foxo3a- and TRAIL-mediated apoptosis.
  J Clin Invest Volume: 121 Page(s): 3877 - 3888
  10/01/2011 Authors: van Grevenynghe J; Cubas RA; Noto A; DaFonseca S; He Z; Peretz Y; Filali-Mouhim A; Dupuy FP; Procopio FA; Chomont N
• Important Contribution of Subdominant HIV-Specific CD8 T Cell Responses to Early Control of HIV Replication
  Volume: 27 Page(s): A12 - A13
  10/01/2011 Authors: Streeck H; Kwon D; Addo M; Flanders M; Davis I; Cutler S; Rychert J; Lane K; Yassine-Diab B; Routy J
• Solving vaccine mysteries: a systems biology perspective.
  Nat Immunol Volume: 12 Page(s): 729 - 731
  07/19/2011 Authors: Trautmann L; Sekaly R-P
• "In vitro systems to characterize the immune response to HIV-1 and HIV-1 vaccine candidates", NIAID Workshop Report, Bethesda, August 4, 2010.
  Volume: 29 Page(s): 4647 - 4653
  06/24/2011 Authors: Malaspina A; Rinaldo CR; Sekaly RP; Flores J; D'Souza PM
• Relative contribution of HIV-specific functional lymphocyte subsets restricted by protective and non-protective HLA alleles.
  Viral Immunol Volume: 24 Page(s): 189 - 198
  06/01/2011 Authors: Peretz Y; Marra O; Thomas R; Legault D; Ct P; Boulassel M-R; Rouleau D; Routy J-P; Skaly R-P; Tsoukas CM
• Unique features of memory T cells in HIV elite controllers: a systems biology perspective.
  Curr Opin HIV AIDS Volume: 6 Page(s): 188 - 196
  05/01/2011 Authors: Fonseca SG; Procopio FA; Goulet J-P; Yassine-Diab B; Ancuta P; Skaly R-P
• Single-cell gene-expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines.
  Proc Natl Acad Sci U S A Volume: 108 Page(s): 5724 - 5729
  04/05/2011 Authors: Flatz L; Roychoudhuri R; Honda M; Filali-Mouhim A; Goulet J-P; Kettaf N; Lin M; Roederer M; Haddad EK; Skaly RP
• A randomized controlled trial of HIV therapeutic vaccination using ALVAC with or without Remune.
  AIDS Volume: 25 Page(s): 731 - 739
  03/27/2011 Authors: Angel JB; Routy J-P; Tremblay C; Ayers D; Woods R; Singer J; Bernard N; Kovacs C; Smaill F; Gurunathan S
• Improved innate and adaptive immunostimulation by genetically modified HIV-1 protein expressing NYVAC vectors.
  PLoS One Volume: 6 Page(s): e16819
  02/15/2011 Authors: Quakkelaar ED; Redeker A; Haddad EK; Harari A; McCaughey SM; Duhen T; Filali-Mouhim A; Goulet J-P; Loof NM; Ossendorp F
• Immunogenicity and tolerability of an inactivated and adjuvanted pandemic H1N1 influenza vaccine, in HIV-1-infected patients.
  Vaccine Volume: 29 Page(s): 1359 - 1363
  02/04/2011 Authors: Tremblay CL; Rouleau D; Fortin C; Toma E; Sylla M; Cyr L; Cote S; Baz M; Sampalis J; Trautman L
• Single cell gene expression profiling reveals qualitatively distinct CD8 T cells elicited by different gene-based vaccines
  Volume: 34 Page(s): 81 - 81
  02/01/2011 Authors: Flatz L; Roychoudhuri R; Honda M; Filali A; Goulet JP; Kettaf N; Roederer M; Haddad E; Sekaly RP; Nabel GJ
• THE ROLE OF 4-1BBL IN RESCUING FUNCTIONALLY IMPAIRED HIV-SPECIFIC CD8 T CELLS
  Volume: 691 Page(s): 766 - 766
  01/01/2011 Authors: Wang C; Wen T; Routy J-P; Bernard NF; Sekaly RP; Watts TH
• Improved NYVAC-based vaccine vectors.
  PLoS One Volume: 6 Page(s): e25674
  01/01/2011 Authors: Kibler KV; Gomez CE; Perdiguero B; Wong S; Huynh T; Holechek S; Arndt W; Jimenez V; Gonzalez-Sanz R; Denzler K
• Maintenance of CD4+ T-cell memory and HIV persistence: keeping memory, keeping HIV.
  Curr Opin HIV AIDS Volume: 6 Page(s): 30 - 36
  01/01/2011 Authors: Chomont N; DaFonseca S; Vandergeeten C; Ancuta P; Skaly R-P
• Optimization of a highly standardized carboxyfluorescein succinimidyl ester flow cytometry panel and gating strategy design using discriminative information measure evaluation.
  Cytometry A Volume: 77 Page(s): 1126 - 1136
  12/01/2010 Authors: Chan C; Lin L; Frelinger J; Hrbert V; Gagnon D; Landry C; Skaly R-P; Enzor J; Staats J; Weinhold KJ
• HTLV-1 evades type I interferon antiviral signaling by inducing the suppressor of cytokine signaling 1 (SOCS1).
  PLoS Pathog Volume: 6 Page(s): e1001177
  11/04/2010 Authors: Olire S; Hernandez E; Lzin A; Arguello M; Douville R; Nguyen TL-A; Olindo S; Panelatti G; Kazanji M; Wilkinson P
• Improvement of the HIV/AIDS vaccine candidate NYVAC-C by deletion of the viral type I IFN inhibitor and/or acquisition of replication competence
  Volume: 26 Page(s): A137 - A137
  10/01/2010 Authors: Kibler KV; Perdiguera B; Gomez CE; Najera JL; Gonzalez-Sanz R; Jimenez V; Quakkelaar ED; Melief CJ; Haddad E; Sekaly R
• Comparison of immune restoration in early versus late alpha interferon therapy against hepatitis C virus.
  J Virol Volume: 84 Page(s): 10429 - 10435
  10/01/2010 Authors: Abdel-Hakeem MS; Bdard N; Badr G; Ostrowski M; Skaly RP; Bruneau J; Willems B; Heathcote EJ; Shoukry NH
• Establishment of HIV-1 latency in resting CD4+ T cells depends on chemokine-induced changes in the actin cytoskeleton.
  Proc Natl Acad Sci U S A Volume: 107 Page(s): 16934 - 16939
  09/28/2010 Authors: Cameron PU; Saleh S; Sallmann G; Solomon A; Wightman F; Evans VA; Boucher G; Haddad EK; Sekaly R-P; Harman AN
• New approaches to design HIV-1 T-cell vaccines.
  Curr Opin HIV AIDS Volume: 5 Page(s): 368 - 376
  09/01/2010 Authors: Perrin H; Canderan G; Skaly R-P; Trautmann L
• Changes in function of HIV-specific T-cell responses with increasing time from infection.
  Viral Immunol Volume: 23 Page(s): 159 - 168
  04/01/2010 Authors: Ndongala ML; Kamya P; Boulet S; Peretz Y; Rouleau D; Tremblay C; Leblanc R; Ct P; Baril J-G; Thomas R
• Programmed death-1-induced interleukin-10 production by monocytes impairs CD4+ T cell activation during HIV infection.
  Nat Med Volume: 16 Page(s): 452 - 459
  04/01/2010 Authors: Said EA; Dupuy FP; Trautmann L; Zhang Y; Shi Y; El-Far M; Hill BJ; Noto A; Ancuta P; Peretz Y
• Dendritic cell inhibition is connected to exhaustion of CD8+ T cell polyfunctionality during chronic hepatitis C virus infection.
  J Immunol Volume: 184 Page(s): 3134 - 3144
  03/15/2010 Authors: Rodrigue-Gervais IG; Rigsby H; Jouan L; Sauv D; Skaly R-P; Willems B; Lamarre D
• Th17 lineage commitment and HIV-1 pathogenesis.
  Curr Opin HIV AIDS Volume: 5 Page(s): 158 - 165
  03/01/2010 Authors: Ancuta P; Monteiro P; Sekaly R-P
• Immunologic activity and safety of autologous HIV RNA-electroporated dendritic cells in HIV-1 infected patients receiving antiretroviral therapy.
  Clin Immunol Volume: 134 Page(s): 140 - 147
  02/01/2010 Authors: Routy J-P; Boulassel M-R; Yassine-Diab B; Nicolette C; Healey D; Jain R; Landry C; Yegorov O; Tcherepanova I; Monesmith T
• Peripheral blood CCR4+CCR6+ and CXCR3+CCR6+CD4+ T cells are highly permissive to HIV-1 infection.
  J Immunol Volume: 184 Page(s): 1604 - 1616
  02/01/2010 Authors: Gosselin A; Monteiro P; Chomont N; Diaz-Griffero F; Said EA; Fonseca S; Wacleche V; El-Far M; Boulassel M-R; Routy J-P
• Differential modulation of CCR5-tropic human immunodeficiency virus-1 transfer from macrophages towards T cells under interleukin-4/interleukin-13 microenvironment.
  Hum Immunol Volume: 71 Page(s): 1 - 13
  01/01/2010 Authors: Sadi H; Carbonneil C; Magri G; Eslahpazir J; Sekaly R-P; Blec L
• A comparative analysis of gene expression patterns and cell phenotypes between cervical and peripheral blood mononuclear cells.
  PLoS One Volume: 4 Page(s): e8293
  12/14/2009 Authors: Horton RE; Kaefer N; Songok E; Guijon FB; Kettaf N; Boucher G; Sekaly R-P; Ball TB; Plummer FA
• siRNA knockdown of PD-L1 and PD-L2 in monocyte-derived dendritic cells only modestly improves proliferative responses to Gag by CD8(+) T cells from HIV-1-infected individuals.
  J Clin Immunol Volume: 29 Page(s): 637 - 645
  09/01/2009 Authors: Breton G; Yassine-Diab B; Cohn L; Boulassel M-R; Routy J-P; Skaly R-P; Steinman RM
• Human immunodeficiency virus type 1-specific CD8+ T-cell responses during primary infection are major determinants of the viral set point and loss of CD4+ T cells.
  J Virol Volume: 83 Page(s): 7641 - 7648
  08/01/2009 Authors: Streeck H; Jolin JS; Qi Y; Yassine-Diab B; Johnson RC; Kwon DS; Addo MM; Brumme C; Routy J-P; Little S
• HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation.
  Nat Med Volume: 15 Page(s): 893 - 900
  08/01/2009 Authors: Chomont N; El-Far M; Ancuta P; Trautmann L; Procopio FA; Yassine-Diab B; Boucher G; Boulassel M-R; Ghattas G; Brenchley JM
• FuGEFlow: data model and markup language for flow cytometry.
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  06/16/2009 Authors: Qian Y; Tchuvatkina O; Spidlen J; Wilkinson P; Gasparetto M; Jones AR; Manion FJ; Scheuermann RH; Sekaly R-P; Brinkman RR
• HIV Gag p24 specific responses secreting IFN-gamma and/or IL-2 in treatment-nave individuals in acute infection early disease (AIED) are associated with low viral load.
  Clin Immunol Volume: 131 Page(s): 277 - 287
  05/01/2009 Authors: Ndongala ML; Peretz Y; Boulet S; Doroudchi M; Yassine-Diab B; Boulassel M-R; Rouleau D; Tremblay C; LeBlanc R; Routy J-P
• A common CD4 gene variant is associated with an increased risk of HIV-1 infection in Kenyan female commercial sex workers.
  J Infect Dis Volume: 199 Page(s): 1327 - 1334
  05/01/2009 Authors: Oyugi JO; Vouriot FCM; Alimonti J; Wayne S; Luo M; Land AM; Ao Z; Yao X; Sekaly RP; Elliott LJ
• Poly (I:C) induced immune response in lymphoid tissues involves three sequential waves of type I IFN expression.
  Virology Volume: 386 Page(s): 225 - 236
  04/10/2009 Authors: Dmoulins T; Baron M-L; Kettaf N; Abdallah A; Sharif-Askari E; Skaly R-P
• Semiquantitation of mouse dendritic cell migration in vivo using cellular MRI.
  J Immunother Volume: 32 Page(s): 240 - 251
  04/01/2009 Authors: Dekaban GA; Snir J; Shrum B; de Chickera S; Willert C; Merrill M; Said EA; Sekaly R-P; Foster PJ; O'Connell PJ
• Transmission and long-term stability of compensated CD8 escape mutations.
  J Virol Volume: 83 Page(s): 3993 - 3997
  04/01/2009 Authors: Schneidewind A; Brumme ZL; Brumme CJ; Power KA; Reyor LL; O'Sullivan K; Gladden A; Hempel U; Kuntzen T; Wang YE
• Regulatory NK Cells Mediate the Decreased Th17 Responses Associated with Abrogated New Disease Activity in MS Patients Treated with Bone Marrow Transplantation
  Volume: 72 Page(s): A469 - A469
  03/17/2009 Authors: Darlington PJ; Doucet J-S; Touil T; Kebir H; Gaucher D; Fawaz L; Zeidan J; Chen J; Jalili F; Gauchat D
• Cellular and molecular mechanisms of memory T-cell survival.
  Expert Rev Vaccines Volume: 8 Page(s): 299 - 312
  03/01/2009 Authors: Tanel A; Fonseca SG; Yassine-Diab B; Bordi R; Zeidan J; Shi Y; Benne C; Skaly R-P
• Immunogenicity of an autologous dendritic cell anti-HIV therapy in HIV-1 infected individuals
  Volume: 6
  01/01/2009 Authors: Diab BY; Coutsinos Z; Landry C; Gagnon D; Sauve D; Hebert-Benoit C; Hebert V; Boulassel M; Routy J; Jain R
• Yellow fever vaccine induces integrated multilineage and polyfunctional immune responses.
  J Exp Med Volume: 205 Page(s): 3119 - 3131
  12/22/2008 Authors: Gaucher D; Therrien R; Kettaf N; Angermann BR; Boucher G; Filali-Mouhim A; Moser JM; Mehta RS; Drake DR; Castro E
• The magnitude of thymic output is genetically determined through controlled intrathymic precursor T cell proliferation.
  J Immunol Volume: 181 Page(s): 7818 - 7824
  12/01/2008 Authors: Dulude G; Cheynier R; Gauchat D; Abdallah A; Kettaf N; Skaly R-P; Gratton S
• Impact of Autologous Dendritic Cell Immunotherapy (Arcelis (TM)) on B Cell Subsets in HIV-1-Infected Subjects Receiving Antiretroviral Therapy
  Volume: 112 Page(s): 37 - 37
  11/16/2008 Authors: Boulassel M-R; Yassine-Diab B; Healey D; Nicolette C; Sekaly R-P; Routy JP
• Reversible blockade of thymic output: an inherent part of TLR ligand-mediated immune response.
  J Immunol Volume: 181 Page(s): 6757 - 6769
  11/15/2008 Authors: Dmoulins T; Abdallah A; Kettaf N; Baron M-L; Gerarduzzi C; Gauchat D; Gratton S; Skaly R-P
• Early interferon therapy for hepatitis C virus infection rescues polyfunctional, long-lived CD8+ memory T cells.
  J Virol Volume: 82 Page(s): 10017 - 10031
  10/01/2008 Authors: Badr G; Bdard N; Abdel-Hakeem MS; Trautmann L; Willems B; Villeneuve J-P; Haddad EK; Skaly RP; Bruneau J; Shoukry NH
• Early CD8+T Cell Responses are the Major Contributors to the Later Viral Set Point
  Volume: 24 Page(s): 7 - 7
  10/01/2008 Authors: Streeck H; Jolin JS; Yassine-Diab B; Qi Y; Kwon D; Addo MM; Johnson R; Brumme C; Routy J; Little S
• Gene Expression Profile in Long-Term Non-Progressor HIV plus Patients: Identification of HIG-2 as a Possible Natural Resistance Factor
  Volume: 24 Page(s): 74 - 74
  10/01/2008 Authors: Santos CC; Mairena E; Fonseca SG; Sekaly R; Wilkinson P; Boucher G; Segurado AC; Fonseca L; Kalil JE; Cunha-Neto E
• Long-term Stability of Compensated CTL Escape Mutations following Acute HIV Infection
  Volume: 24 Page(s): 78 - 78
  10/01/2008 Authors: Schneidewind A; Brumme ZL; Brume CJ; Power KA; Reyor LL; O'Sullivan K; Jessen H; Markowitz M; Rosenberg ES; Sekaly R
• STAT5 Phosphorylation Patterns in T Cell Subsets from Subtype C HIV-1 Infected Individuals
  Volume: 24 Page(s): 125 - 126
  10/01/2008 Authors: Malatsi NO; Riou C; Sekaly R; Gray C
• Type I IFNs affect early thymocyte development
  Volume: 43 Page(s): 309 - 310
  09/01/2008 Authors: Gauchat D; Baron M-L; La Motte-Mohs R; Zuniga-Pflueker J-C; Sekaly R-P
• Impaired signaling in memory T-cells during HIV infection
  Volume: 43 Page(s): 241 - 242
  09/01/2008 Authors: Shi Y; Trautmann L; Peretz Y; Zeidan J; Yassine-Diab B; He Z; Boulassel M-R; Routy J-P; Haddad EK; Sekaly R-P
• Early but not late interferon alpha therapy against hepatitis C rescues pollyfunctional CD4+and CD8+memory T cells
  Volume: 43 Page(s): 306 - 307
  09/01/2008 Authors: Abdel-Hakeem MS; Bedard N; Badr G; Ostrowski M; Bruneau J; Sekaly RP; Willems B; Heathcote JE; Shoukry NH
• Type I IFN and ISG expression in primary hepatocytes following dsRNA stimulation and expression disruption by HCV protease NS3/4A
  Volume: 43 Page(s): 301 - 301
  09/01/2008 Authors: Jouan L; Melancon P; Rodrigue-Gervais IG; Raymond V-A; Selliah S; Bilodeau M; Sekaly R-P; Grandvaux N; Lamarre D
• Elite controllers are enriched with HIV-specific cells expressing CD160 but lacking PD1
  Volume: 43 Page(s): 275 - 275
  09/01/2008 Authors: Peretz Y; Shi Y; He Z; Trautmann L; Diab BY; Haddad E; Sekaly R-P
• Persistence of restricted CD4 T cell expansions in SIV-infected macaques resistant to SHIV89.6P superinfection.
  Virology Volume: 377 Page(s): 239 - 247
  08/01/2008 Authors: Salha M-D; Cheynier R; Halwani R; McGrath H; Langaee TY; Yassine Diab B; Fournier J; Parenteau M; Edgar J; Ko D
• Therapeutic vaccination with simian immunodeficiency virus (SIV)-DNA + IL-12 or IL-15 induces distinct CD8 memory subsets in SIV-infected macaques.
  J Immunol Volume: 180 Page(s): 7969 - 7979
  06/15/2008 Authors: Halwani R; Boyer JD; Yassine-Diab B; Haddad EK; Robinson TM; Kumar S; Parkinson R; Wu L; Sidhu MK; Phillipson-Weiner R
• Lymph node architecture collapse and consequent modulation of FOXO3a pathway on memory T- and B-cells during HIV infection.
  Semin Immunol Volume: 20 Page(s): 196 - 203
  06/01/2008 Authors: van Grevenynghe J; Halwani R; Chomont N; Ancuta P; Peretz Y; Tanel A; Procopio FA; shi Y; Said EA; Haddad EK
• TLR Ligand-Induced Type I IFNs Affect Thymopoiesis.
  J Immunol Volume: 180 Page(s): 7134 - 7146
  06/01/2008 Authors: Baron M-L; Gauchat D; La Motte-Mohs R; Kettaf N; Abdallah A; Michiels T; Ziga-Pflcker J-C; Skaly R-P
• Persistent human immunodeficiency virus-1 antigenaemia affects the expression of interleukin-7Ralpha on central and effector memory CD4+ and CD8+ T cell subsets.
  Clin Exp Immunol Volume: 152 Page(s): 72 - 80
  04/01/2008 Authors: Mercier F; Boulassel M-R; Yassine-Diab B; Tremblay C; Bernard N-F; Sekaly R-P; Routy J-P
• Type-I interferons inhibit Delta-like-1-dependent T cell development and increase apoptosis of developing thymocytes in vitro
  Volume: 22
  04/01/2008 Authors: La Motte-Mohs R; Gauchat-Feiss D; Baron M-L; Demoulins T; Awong G; Michiels T; Perreault C; Zuniga-Pfluecker JC; Sekaly R-P
• Inhibition of HIV-1 transmission in trans from dendritic cells to CD4+ T lymphocytes by natural antibodies to the CRD domain of DC-SIGN purified from breast milk and intravenous immunoglobulins.
  Immunology Volume: 123 Page(s): 508 - 518
  04/01/2008 Authors: Requena M; Bouhlal H; Nasreddine N; Saidi H; Gody J-C; Aubry S; Grsenguet G; Kazatchkine MD; Sekaly R-P; Blec L
• 4-1BBL is a critical component in the costimulation dependent rescue of functionally impaired HIV-specific CTL
  Volume: 22
  04/01/2008 Authors: Wang C; Wen T; Routy J-P; Bernard N; Sekaly R; Watts T
• The dramatic abrogation of inflammatory disease activity in MS patients treated with immune ablation and autologous haematopoetic stem-cell transplantation (AHSCT) us associated with significant decreases in ThIL-17, but not in th1 responses
  Volume: 70 Page(s): A246 - A246
  03/11/2008 Authors: Touil T; Gaucher D; Kebir H; Zeidan J; Kim HJ; Corsini R; Gauchat D; Duddy M; Jalili F; Chen J
• Transcription factor FOXO3a controls the persistence of memory CD4(+) T cells during HIV infection.
  Nat Med Volume: 14 Page(s): 266 - 274
  03/01/2008 Authors: van Grevenynghe J; Procopio FA; He Z; Chomont N; Riou C; Zhang Y; Gimmig S; Boucher G; Wilkinson P; Shi Y
• Why T cells of thymic versus extrathymic origin are functionally different.
  J Immunol Volume: 180 Page(s): 2299 - 2312
  02/15/2008 Authors: Blais M-E; Brochu S; Giroux M; Blanger M-P; Dulude G; Skaly R-P; Perreault C
• Magnetization transfer ratio evolution with demyelination and remyelination in multiple sclerosis lesions.
  Ann Neurol Volume: 63 Page(s): 254 - 262
  02/01/2008 Authors: Chen JT; Collins DL; Atkins HL; Freedman MS; Arnold DL; Canadian MS/BMT Study Group
• T-cell exhaustion in HIV infection.
  Curr HIV/AIDS Rep Volume: 5 Page(s): 13 - 19
  02/01/2008 Authors: El-Far M; Halwani R; Said E; Trautmann L; Doroudchi M; Janbazian L; Fonseca S; van Grevenynghe J; Yassine-Diab B; Skaly R-P
• The failed HIV Merck vaccine study: a step back or a launching point for future vaccine development?
  J Exp Med Volume: 205 Page(s): 7 - 12
  01/21/2008 Authors: Sekaly R-P
• 4-1BBL induces TNF receptor-associated factor 1-dependent Bim modulation in human T cells and is a critical component in the costimulation-dependent rescue of functionally impaired HIV-specific CD8 T cells.
  J Immunol Volume: 179 Page(s): 8252 - 8263
  12/15/2007 Authors: Wang C; Wen T; Routy J-P; Bernard NF; Sekaly RP; Watts TH
• p56Lck tyrosine kinase enhances the assembly of death-inducing signaling complex during Fas-mediated apoptosis.
  J Biol Chem Volume: 282 Page(s): 36048 - 36056
  12/07/2007 Authors: Sharif-Askari E; Gaucher D; Halwani R; Ma J; Jao K; Abdallah A; Haddad EK; Skaly R-P
• Filter selection for five color flow cytometric analysis with a single laser.
  Int J Lab Hematol Volume: 29 Page(s): 369 - 376
  10/01/2007 Authors: Braun RK; Rudnicki MA; Sekaly RP; Filion LG
• Functional T cell subsets contribute differentially to HIV peptide-specific responses within infected individuals: correlation of these functional T cell subsets with markers of disease progression.
  Clin Immunol Volume: 124 Page(s): 57 - 68
  07/01/2007 Authors: Peretz Y; Ndongala ML; Boulet S; Boulassel MR; Rouleau D; Ct P; Longpr D; Routy J-P; Falutz J; Tremblay C
• Recognition of a defined region within p24 gag by CD8+ T cells during primary human immunodeficiency virus type 1 infection in individuals expressing protective HLA class I alleles.
  J Virol Volume: 81 Page(s): 7725 - 7731
  07/01/2007 Authors: Streeck H; Lichterfeld M; Alter G; Meier A; Teigen N; Yassine-Diab B; Sidhu HK; Little S; Kelleher A; Routy J-P
• Poly(I:C) and lipopolysaccharide innate sensing functions of circulating human myeloid dendritic cells are affected in vivo in hepatitis C virus-infected patients.
  J Virol Volume: 81 Page(s): 5537 - 5546
  06/01/2007 Authors: Rodrigue-Gervais IG; Jouan L; Beaul G; Sauv D; Bruneau J; Willems B; Skaly R-P; Lamarre D
• Programmed death 1: a critical regulator of T-cell function and a strong target for immunotherapies for chronic viral infections.
  Curr Opin HIV AIDS Volume: 2 Page(s): 219 - 227
  05/01/2007 Authors: Trautmann L; Said EA; Halwani R; Janbazian L; Chomont N; El-Far M; Breton G; Haddad EK; Sekaly R-P
• Slow disease progression and robust therapy-mediated CD4+ T-cell recovery are associated with efficient thymopoiesis during HIV-1 infection.
  Blood Volume: 109 Page(s): 2912 - 2920
  04/01/2007 Authors: Dion M-L; Bordi R; Zeidan J; Asaad R; Boulassel M-R; Routy J-P; Lederman MM; Sekaly R-P; Cheynier R
• A dual color ELISPOT method for the simultaneous detection of IL-2 and IFN-gamma HIV-specific immune responses.
  J Immunol Methods Volume: 320 Page(s): 18 - 29
  03/30/2007 Authors: Boulet S; Ndongala ML; Peretz Y; Boisvert M-P; Boulassel M-R; Tremblay C; Routy J-P; Sekaly R-P; Bernard NF
• [mRNA-transfected dendritic cells: a promising strategy in immunotherapy].
  Med Sci (Paris) Volume: 23 Page(s): 279 - 284
  03/01/2007 Authors: Maisnier-Patin K; Crab S; Breton G; Dupuy FP; Yassine-Diab B; Skaly R-P
• Drug resistance mutations and the cellular immune response: a valuable synergy for the development of novel immune therapies.
  Curr Opin HIV AIDS Volume: 2 Page(s): 116 - 122
  03/01/2007 Authors: Chomont N; Trautmann L; Routy J-P; Skaly R-P
• Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells.
  J Exp Med Volume: 204 Page(s): 79 - 91
  01/22/2007 Authors: Riou C; Yassine-Diab B; Van grevenynghe J; Somogyi R; Greller LD; Gagnon D; Gimmig S; Wilkinson P; Shi Y; Cameron MJ
• The duration of exposure to HIV modulates the breadth and the magnitude of HIV-specific memory CD4+ T cells.
  J Immunol Volume: 178 Page(s): 788 - 797
  01/15/2007 Authors: Younes S-A; Trautmann L; Yassine-Diab B; Kalfayan LH; Kernaleguen A-E; Cameron TO; Boulassel R; Stern LJ; Routy J-P; Grossman Z
• Estimating thymic function through quantification of T-cell receptor excision circles.
  Methods Mol Biol Volume: 380 Page(s): 197 - 213
  01/01/2007 Authors: Dion M-L; Skaly R-P; Cheynier R
• Prediction of graft-versus-host disease in humans by donor gene-expression profiling.
  PLoS Med Volume: 4 Page(s): e23
  01/01/2007 Authors: Baron C; Somogyi R; Greller LD; Rineau V; Wilkinson P; Cho CR; Cameron MJ; Kelvin DJ; Chagnon P; Roy D-C
• [Inhibition of the PD-1 pathway restores the effector function of HIV-specific T cells].
  Med Sci (Paris) Volume: 23 Page(s): 24 - 25
  01/01/2007 Authors: Trautmann L; Chomont N; Skaly R-P
• Identification of a chimeric CD80/CD86 and steap antigen containing adenoviral vector for therapeutic vaccine against prostate cancer
  Volume: 29 Page(s): 667 - 667
  11/01/2006 Authors: Maisnier-Patin K; Wen T; Landry C; Li X; Bergeron A; Fradet I; Sekaly R-P
• Generation and maintenance of human memory cells during viral infection.
  Springer Semin Immunopathol Volume: 28 Page(s): 197 - 208
  11/01/2006 Authors: Halwani R; Doroudchi M; Yassine-Diab B; Janbazian L; Shi Y; Said EA; Haddad EK; Skaly R-P
• Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction.
  Nat Med Volume: 12 Page(s): 1198 - 1202
  10/01/2006 Authors: Trautmann L; Janbazian L; Chomont N; Said EA; Gimmig S; Bessette B; Boulassel M-R; Delwart E; Sepulveda H; Balderas RS
• IL-4 influences the differentiation and the susceptibility to activation-induced cell death of human naive CD8+ T cells.
  Int Immunol Volume: 18 Page(s): 827 - 835
  06/01/2006 Authors: Riou C; Dumont AR; Yassine-Diab B; Haddad EK; Sekaly R-P
• Triggering of T cell activation via CD4 dimers.
  J Immunol Volume: 176 Page(s): 5438 - 5445
  05/01/2006 Authors: Moldovan M-C; Sabbagh L; Breton G; Skaly R-P; Krummel MF
• Immune reconstitution after CD8-depleted or unmanipulated peripheral blood stem cells transplantation following nonmyeloablative conditioning: Results from a prospective randomized trial
  Volume: 12 Page(s): 81 - 81
  02/01/2006 Authors: Castermans E; Baron F; Willems E; Meuris N; Schaaf-Lafontaine N; Cheynier R; Geenen V; Sekaly RP; Beguin Y
• Cloning and functional characterization of the murine caspase-3 gene promoter.
  DNA Cell Biol Volume: 25 Page(s): 104 - 115
  02/01/2006 Authors: Sabbagh L; Bourbonnire M; Denis F; Skaly R-P
• Expression of interleukin-7 receptor and activation markers on central memory CD8 cells in HIV-infected individuals treated with antiretrovirals.
  Volume: 106 Page(s): 415A - 415A
  11/16/2005 Authors: Routy JP; Boulassel MR; Mercier F; Grignon C; Young M; Legault M; Tremblay C; Cheynier R; Sekaly RP
• Evaluation of OX40 ligand as a costimulator of human antiviral memory CD8 T cell responses: comparison with B7.1 and 4-1BBL.
  J Immunol Volume: 175 Page(s): 6368 - 6377
  11/15/2005 Authors: Serghides L; Bukczynski J; Wen T; Wang C; Routy J-P; Boulassel M-R; Sekaly R-P; Ostrowski M; Bernard NF; Watts TH
• Enhancement of HIV-specific CD8 T cell responses by dual costimulation with CD80 and CD137L.
  J Immunol Volume: 175 Page(s): 6378 - 6389
  11/15/2005 Authors: Bukczynski J; Wen T; Wang C; Christie N; Routy J-P; Boulassel M-R; Kovacs CM; Macdonald KS; Ostrowski M; Sekaly R-P
• Selective up-regulation of caspase-3 gene expression following TCR engagement.
  Mol Immunol Volume: 42 Page(s): 1345 - 1354
  07/01/2005 Authors: Sabbagh L; Bourbonnire M; Skaly R-P; Cohen LY
• Delayed expansion of a restricted T cell repertoire by low-density TCR ligands.
  Int Immunol Volume: 17 Page(s): 931 - 941
  07/01/2005 Authors: Lavoie PM; Dumont AR; McGrath H; Kernaleguen A-E; Skaly R-P
• Standardization of cytokine flow cytometry assays.
  BMC Immunol Volume: 6 Page(s): 13
  06/24/2005 Authors: Maecker HT; Rinfret A; D'Souza P; Darden J; Roig E; Landry C; Hayes P; Birungi J; Anzala O; Garcia M
• A defective viral superantigen-presenting phenotype in HLA-DR transfectants is corrected by CIITA.
  J Immunol Volume: 174 Page(s): 7548 - 7557
  06/15/2005 Authors: Azar GA; Skaly R-P; Thibodeau J
• Local magnetization transfer ratio signal inhomogeneity is related to subsequent change in MTR in lesions and normal-appearing white-matter of multiple sclerosis patients.
  Neuroimage Volume: 25 Page(s): 1272 - 1278
  05/01/2005 Authors: Chen JT; Collins DL; Freedman MS; Atkins HL; Arnold DL; Canadian MS/BMT Study Group
• CD4 down-regulation by HIV-1 and simian immunodeficiency virus (SIV) Nef proteins involves both internalization and intracellular retention mechanisms.
  J Biol Chem Volume: 280 Page(s): 7413 - 7426
  03/04/2005 Authors: Rose JJ; Janvier K; Chandrasekhar S; Sekaly RP; Bonifacino JS; Venkatesan S
• Notch1 antiapoptotic activity is abrogated by caspase cleavage in dying T lymphocytes.
  Cell Death Differ Volume: 12 Page(s): 243 - 254
  03/01/2005 Authors: Cohen LY; Bourbonnire M; Sabbagh L; Bouchard A; Chew T; Jeannequin P; Lazure C; Skaly R-P
• HIV infection rapidly induces and maintains a substantial suppression of thymocyte proliferation.
  Immunity Volume: 21 Page(s): 757 - 768
  12/01/2004 Authors: Dion M-L; Poulin J-F; Bordi R; Sylvestre M; Corsini R; Kettaf N; Dalloul A; Boulassel M-R; Debr P; Routy J-P
• Factors associated with a decrease in the prevalence of drug resistance in newly HIV-1 infected individuals in Montreal.
  AIDS Volume: 18 Page(s): 2305 - 2312
  11/19/2004 Authors: Routy J-P; Machouf N; Edwardes MD; Brenner BG; Thomas R; Trottier B; Rouleau D; Tremblay CL; Ct P; Baril J-G
• Persistence of high viral load abrogates long-term HIV-specific memory CD4 T-cells producing interleukin-2.
  Volume: 104 Page(s): 848A - 848A
  11/16/2004 Authors: Boulassel MR; Younes SA; Yacine-Diab B; Sekaly RP; Routy JP
• The selective increase in caspase-3 expression in effector but not memory T cells allows susceptibility to apoptosis.
  J Immunol Volume: 173 Page(s): 5425 - 5433
  11/01/2004 Authors: Sabbagh L; Kaech SM; Bourbonnire M; Woo M; Cohen LY; Haddad EK; Labrecque N; Ahmed R; Skaly R-P
• Assessment of longitudinal changes in HIV-specific effector activity in subjects undergoing untreated primary HIV infection.
  AIDS Volume: 18 Page(s): 1979 - 1989
  10/21/2004 Authors: Alter G; Tsoukas CM; Rouleau D; Ct P; Routy J-P; Skaly R-P; Bernard NF
• Support for the RV144 HIV vaccine trial.
  Science Volume: 305 Page(s): 177 - 180
  07/09/2004 Authors: Belshe R; Franchini G; Girard MP; Gotch F; Kaleebu P; Marthas ML; McChesney MB; McCullough R; Mhalu F; Salmon-Ceron D
• Support for the RV144 HIV vaccine trial.
  Science Volume: 305 Page(s): 177 - 180
  07/09/2004 Authors: AIDS Vaccine Advocacy Coalition
• Spontaneous reconstitution of T-cell reactivity to self-antigen in multiple sclerosis patients following immune ablation and autologous stem cell rescue
  Volume: 251 Page(s): 48 - 49
  06/01/2004 Authors: Bar-Or A; Kim H; Corsini R; Gauchat D; Duddy M; Jalili E; Bowman M; Atkins H; Freedman M; Sekaly R
• Modulation of immune responses - strategies for optimising vaccines.
  Expert Opin Biol Ther Volume: 4 Page(s): 627 - 630
  05/01/2004 Authors: Dumont AR; Kalfayan LH; Skaly R-P
• Caspase-3 is a component of Fas death-inducing signaling complex in lipid rafts and its activity is required for complete caspase-8 activation during Fas-mediated cell death.
  J Immunol Volume: 172 Page(s): 2316 - 2323
  02/15/2004 Authors: Aouad SM; Cohen LY; Sharif-Askari E; Haddad EK; Alam A; Sekaly R-P
• Immune events following immunoablative therapy for the treatment of multiple sclerosis (MS)
  Volume: 10 Page(s): 62 - 62
  02/01/2004 Authors: Atkins H; Freedman M; Bowman M; Bar-Or A; Cheynier R; Corsini R; Jalili F; Kim HJ; Miller L; Sekaly R
• Circulating levels of IL-7 but not IL-15, IGF-1, and TGF-beta are elevated during primary HIV-1 infection.
  HIV Clin Trials Volume: 5 Page(s): 357 - 359
  01/01/2004 Authors: Boulassel MR; Young M; Routy JP; Sekaly RP; Tremblay C; Rouleau D
• Evidence for adequate thymic function but impaired naive T-cell survival following allogeneic hematopoietic stem cell transplantation in the absence of chronic graft-versus-host disease.
  Blood Volume: 102 Page(s): 4600 - 4607
  12/15/2003 Authors: Poulin J-F; Sylvestre M; Champagne P; Dion M-L; Kettaf N; Dumont A; Lainesse M; Fontaine P; Roy D-C; Perreault C
• HIV-1 viremia prevents the establishment of interleukin 2-producing HIV-specific memory CD4+ T cells endowed with proliferative capacity.
  J Exp Med Volume: 198 Page(s): 1909 - 1922
  12/15/2003 Authors: Younes S-A; Yassine-Diab B; Dumont AR; Boulassel M-R; Grossman Z; Routy J-P; Sekaly R-P
• Influence of HLA-B57 on clinical presentation and viral control during acute HIV-1 infection.
  AIDS Volume: 17 Page(s): 2581 - 2591
  12/05/2003 Authors: Altfeld M; Addo MM; Rosenberg ES; Hecht FM; Lee PK; Vogel M; Yu XG; Draenert R; Johnston MN; Strick D
• Associations among circulating interleukin-7, RANTES, TGF-beta, disease progression and CD4 cell recovery in HIV-1 infected patients.
  Volume: 102 Page(s): 282A - 282A
  11/16/2003 Authors: Routy JP; Young M; Sekaly RP; Boulassel MR
• Costimulatory molecule immune enhancement in a plasmid vaccine model is regulated in part through the Ig constant-like domain of CD80/86.
  J Immunol Volume: 171 Page(s): 4311 - 4319
  10/15/2003 Authors: Agadjanyan MG; Chattergoon MA; Holterman MJ; Monzavi-Karbassi B; Kim JJ; Dentchev T; Wilson D; Ayyavoo V; Montaner LJ; Kieber-Emmons T
• The MHC class II beta chain cytoplasmic tail overcomes the invariant chain p35-encoded endoplasmic reticulum retention signal.
  Int Immunol Volume: 15 Page(s): 1249 - 1263
  10/01/2003 Authors: Khalil H; Brunet A; Saba I; Terra R; Skaly RP; Thibodeau J
• Diminished proliferation of human immunodeficiency virus-specific CD4+ T cells is associated with diminished interleukin-2 (IL-2) production and is recovered by exogenous IL-2.
  J Virol Volume: 77 Page(s): 10900 - 10909
  10/01/2003 Authors: Iyasere C; Tilton JC; Johnson AJ; Younes S; Yassine-Diab B; Sekaly R-P; Kwok WW; Migueles SA; Laborico AC; Shupert WL
• Longitudinal assessment of changes in HIV-specific effector activity in HIV-infected patients starting highly active antiretroviral therapy in primary infection.
  J Immunol Volume: 171 Page(s): 477 - 488
  07/01/2003 Authors: Alter G; Hatzakis G; Tsoukas CM; Pelley K; Rouleau D; LeBlanc R; Baril JG; Dion H; Lefebvre E; Thomas R
• Drug resistance prevalence declines in recently infected subjects having sex with men but not in those using drug injections: results from the Montreal Primary HIV-Infection Cohort
  Volume: 8 Page(s): U118 - U119
  06/01/2003 Authors: Routy JP; Brenner B; Rouleau D; Thomas R; Trottier B; Cote P; Baril JG; Tremblay C; Leblanc R; Edwardes M
• Early activation events differentiate the reactivity of two T-cell families to Staphylococcus enterotoxin A.
  Cell Immunol Volume: 223 Page(s): 113 - 119
  06/01/2003 Authors: D'Souza S; McGrath H; Skaly RP
• Immunoablative therapy with purified autologous stem cells rescue for the treatment of poor prognosis multiple sclerosis
  Volume: 31 Page(s): S101 - S101
  03/01/2003 Authors: Huebsch L; Atkins H; Freedman M; Bowman M; Antel J; Douglas A; Bence-Bruckler I; Bar-Or A; Chen J; Cheynier R
• Estimate of the total number of CD8+ clonal expansions in healthy adults using a new DNA heteroduplex-tracking assay for CDR3 repertoire analysis.
  J Immunol Methods Volume: 274 Page(s): 159 - 175
  03/01/2003 Authors: Bernardin F; Doukhan L; Longone-Miller A; Champagne P; Sekaly R; Delwart E
• Quantification of T cell receptor rearrangement excision circles to estimate thymic function: an important new tool for endocrine-immune physiology.
  J Endocrinol Volume: 176 Page(s): 305 - 311
  03/01/2003 Authors: Geenen V; Poulin J-F; Dion ML; Martens H; Castermans E; I Hansenne; Moutschen M; Skaly RP; Cheynier R
• Vaccination with a simplified simian immunodeficiency virus deleted of all accessory genes
  Page(s): 97 - 103
  01/01/2003 Authors: Wainberg MA; Guan YJ; Detorio M; MacDonald K; Rosenthal K; Sekaly RP; Fournier J; Sandstrom P
• Changes in immunological and virological parameters in HIV-1 infected subjects following leukapheresis.
  J Clin Apher Volume: 18 Page(s): 55 - 60
  01/01/2003 Authors: Boulassel MR; Spurll G; Rouleau D; Tremblay C; Edwardes M; Sekaly RP; Lalonde R; Routy J-P
• CD4 dimers constitute the functional component required for T cell activation.
  J Immunol Volume: 169 Page(s): 6261 - 6268
  12/01/2002 Authors: Moldovan M-C; Yachou A; Lvesque K; Wu H; Hendrickson WA; Cohen EA; Skaly R-P
• Distribution and functional analysis of memory antiviral CD8 T cell responses in HIV-1 and cytomegalovirus infections.
  Eur J Immunol Volume: 32 Page(s): 3756 - 3764
  12/01/2002 Authors: Ellefsen K; Harari A; Champagne P; Bart P-A; Skaly R-P; Pantaleo G
• HIV-1 protease processes procaspase 8 to cause mitochondrial release of cytochrome c, caspase cleavage and nuclear fragmentation.
  Cell Death Differ Volume: 9 Page(s): 1172 - 1184
  11/01/2002 Authors: Nie Z; Phenix BN; Lum JJ; Alam A; Lynch DH; Beckett B; Krammer PH; Sekaly RP; Badley AD
• Clinical features of acute retroviral syndrome differ by route of infection but not by gender and age.
  J Acquir Immune Defic Syndr Volume: 31 Page(s): 318 - 321
  11/01/2002 Authors: Vanhems P; Routy J-P; Hirschel B; Baratin D; Vora S; Maenza J; Carr A; Trpo C; Touraine J-L; Gillibert R-P
• HIV-specific CD8 T-cell activity in uninfected injection drug users is associated with maintenance of seronegativity.
  AIDS Volume: 16 Page(s): 1595 - 1602
  08/16/2002 Authors: Makedonas G; Bruneau J; Lin H; Skaly R-P; Lamothe F; Bernard NF
• Human immunodeficiency virus (HIV)-specific effector CD8 T cell activity in patients with primary HIV infection.
  J Infect Dis Volume: 185 Page(s): 755 - 765
  03/15/2002 Authors: Alter G; Merchant A; Tsoukas CM; Rouleau D; LeBlanc RP; Ct P; Baril J-G; Thomas R; Nguyen V-K; Skaly R-P
• Persistence and fitness of multidrug-resistant human immunodeficiency virus type 1 acquired in primary infection.
  J Virol Volume: 76 Page(s): 1753 - 1761
  02/01/2002 Authors: Brenner BG; Routy J-P; Petrella M; Moisi D; Oliveira M; Detorio M; Spira B; Essabag V; Conway B; Lalonde R
• Next generation DNA vaccines for HIV-1.
  J Liposome Res Volume: 12 Page(s): 137 - 142
  01/01/2002 Authors: Boyer JD; Chattergoon M; Muthumani K; Kudchodkar S; Kim J; Bagarazzi M; Pavlakis G; Sekaly R; Weiner DB
• Link between the declines of drug-resistance prevalence in newly infected individuals and of the proportion of patients receiving treatment in Montreal
  Volume: 7 Page(s): S193 - S193
  01/01/2002 Authors: Routy JP; Brenner B; Bruce S; Machouf N; Spira B; Legault M; Thomas R; Trottier B; Rouleau D; Cote P
• Learning to remember: generation and maintenance of T-cell memory.
  DNA Cell Biol Volume: 20 Page(s): 745 - 760
  12/01/2001 Authors: Champagne P; Dumont AR; Skaly RP
• Alteration of the IL-7 homeostatic response to T-cell depletion during the course of HIV-infection is independent of viremia.
  Volume: 98 Page(s): 501A - 501A
  11/16/2001 Authors: Routy JP; Boulassel MRR; Conway B; Sekaly RP
• Thymic output and interleukin-7 (IL-7) levels during primary HIV-infection.
  Volume: 98 Page(s): 501A - 501A
  11/16/2001 Authors: Routy JP; Sylvestre M; Poulin JF; Sekaly RP; Cheynier R
• Quantitative relationship between MHC class II-superantigen complexes and the balance of T cell activation versus death.
  J Immunol Volume: 166 Page(s): 7229 - 7237
  06/15/2001 Authors: Lavoie PM; McGrath H; Shoukry NH; Cazenave PA; Skaly RP; Thibodeau J
• Direct cleavage of the human DNA fragmentation factor-45 by granzyme B induces caspase-activated DNase release and DNA fragmentation.
  EMBO J Volume: 20 Page(s): 3101 - 3113
  06/15/2001 Authors: Sharif-Askari E; Alam A; Rhaume E; Beresford PJ; Scotto C; Sharma K; Lee D; DeWolf WE; Nuttall ME; Lieberman J
• Skewed maturation of memory HIV-specific CD8 T lymphocytes.
  Nature Volume: 410 Page(s): 106 - 111
  03/01/2001 Authors: Champagne P; Ogg GS; King AS; Knabenhans C; Ellefsen K; Nobile M; Appay V; Rizzardi GP; Fleury S; Lipp M
• Cutting edge: Detection of antigen-specific CD4(+) T cells by HLA-DR1 oligomers is dependent on the T cell activation state. (vol 166, pg 741, 2001)
  JOURNAL OF IMMUNOLOGY Volume: 166 Page(s): 2887 - 2887
  02/15/2001 Authors: Cameron TO; Cochran JR; Yassine-Diab B; Sekaly RP; Stern LJ
• Cutting edge: detection of antigen-specific CD4+ T cells by HLA-DR1 oligomers is dependent on the T cell activation state.
  J Immunol Volume: 166 Page(s): 741 - 745
  01/15/2001 Authors: Cameron TO; Cochran JR; Yassine-Diab B; Skaly RP; Stern LJ
• Substantial differences in specificity of HIV-specific cytotoxic T cells in acute and chronic HIV infection.
  J Exp Med Volume: 193 Page(s): 181 - 194
  01/15/2001 Authors: Goulder PJ; Altfeld MA; Rosenberg ES; Nguyen T; Tang Y; Eldridge RL; Addo MM; He S; Mukherjee JS; Phillips MN
• Resistance to antiretroviral drugs in patients with primary HIV-1 infection. Investigators of the Quebec Primary Infection Study.
  Int J Antimicrob Agents Volume: 16 Page(s): 429 - 434
  12/01/2000 Authors: Brenner B; Wainberg MA; Salomon H; Rouleau D; Dascal A; Spira B; Sekaly RP; Conway B; Routy JP
• Identification of dominant optimal HLA-B60- and HLA-B61-restricted cytotoxic T-lymphocyte (CTL) epitopes: rapid characterization of CTL responses by enzyme-linked immunospot assay.
  J Virol Volume: 74 Page(s): 8541 - 8549
  09/01/2000 Authors: Altfeld MA; Trocha A; Eldridge RL; Rosenberg ES; Phillips MN; Addo MM; Sekaly RP; Kalams SA; Burchett SA; McIntosh K
• Comparison of Clinical Features of Acute HIV-1 Infection in Patients Infected Sexually or Through Injection Drug Use.
  J Acquir Immune Defic Syndr Volume: 24 Page(s): 425 - 432
  08/15/2000 Authors: Routy JP; Vanhems P; Rouleau D; Tsoukas C; Lefbvre E; Ct P; LeBlanc R; Conway B; Alary M; Bruneau J
• Comparison of clinical features of acute HIV-1 infection in patients infected sexually or through injection drug use. The Investigators of the Qubec Primary HIV Infection Study.
  J Acquir Immune Defic Syndr Volume: 24 Page(s): 425 - 432
  08/15/2000 Authors: Routy JP; Vanhems P; Rouleau D; Tsoukas C; Lefbvre E; Ct P; LeBlanc R; Conway B; Alary M; Bruneau J
• Mechanism of activation of caspases in proliferating nonapoptotic T cells
  Volume: 14 Page(s): A1222 - A1222
  04/20/2000 Authors: Aouad SM; Cohen LY; Sekaly RP
• Caracterization of HIV positive CD4 T lymphocytes by MHC class II tetramers.
  Volume: 14 Page(s): A979 - A979
  04/20/2000 Authors: Younes SA; Yassine-Diab B; Sekaly RP
• Detection of T cell receptor circles (TRECs) as biomarkers for de novo T cell synthesis using a quantitative polymerase chain reaction-enzyme linked immunosorbent assay (PCR-ELISA).
  J Immunol Methods Volume: 237 Page(s): 187 - 197
  04/03/2000 Authors: Al-Harthi L; Marchetti G; Steffens CM; Poulin J; Skaly R; Landay A
• The extracellular domain of CD4 regulates the initiation of T cell activation.
  Mol Immunol Volume: 37 Page(s): 213 - 219
  04/01/2000 Authors: Gratton S; Haughn L; Sekaly RP; Julius M
• Alternative proteolytic processing of mouse mammary tumor virus superantigens.
  J Virol Volume: 74 Page(s): 3067 - 3073
  04/01/2000 Authors: Denis F; Shoukry NH; Delcourt M; Thibodeau J; Labrecque N; McGrath H; Munzer JS; Seidah NG; Skaly RP
• Prevalence of HIV-1 resistant to antiretroviral drugs in 81 individuals newly infected by sexual contact or injecting drug use. Investigators of the Quebec Primary Infection Study.
  AIDS Volume: 14 Page(s): F17 - F23
  01/28/2000 Authors: Salomon H; Wainberg MA; Brenner B; Quan Y; Rouleau D; Cot P; LeBlanc R; Lefebvre E; Spira B; Tsoukas C
• Superantigen presenting capacity of human astrocytes.
  J Neuroimmunol Volume: 102 Page(s): 131 - 136
  01/24/2000 Authors: Hassan-Zahraee M; Ladiwala U; Lavoie PM; McCrea E; Sekaly RP; Owens T; Antel JP
• Transient T cell receptor beta-chain variable region-specific expansions of CD4+ and CD8+ T cells during the early phase of pediatric human immunodeficiency virus infection: characterization of expanded cell populations by T cell receptor phenotyping.
  J Infect Dis Volume: 181 Page(s): 107 - 120
  01/01/2000 Authors: Soudeyns H; Champagne P; Holloway CL; Silvestri GU; Ringuette N; Samson J; Lapointe N; Skaly RP
• Early activation of caspases during T lymphocyte stimulation results in selective substrate cleavage in nonapoptotic cells.
  J Exp Med Volume: 190 Page(s): 1879 - 1890
  12/20/1999 Authors: Alam A; Cohen LY; Aouad S; Skaly RP
• Binding of soluble recombinant HIV envelope glycoprotein, rgp120, induces conformational changes in the cellular membrane-anchored CD4 molecule.
  Biochem Biophys Res Commun Volume: 265 Page(s): 428 - 433
  11/19/1999 Authors: Yachou A; Skaly RP
• Direct evidence for thymic function in adult humans.
  J Exp Med Volume: 190 Page(s): 479 - 486
  08/16/1999 Authors: Poulin JF; Viswanathan MN; Harris JM; Komanduri KV; Wieder E; Ringuette N; Jenkins M; McCune JM; Skaly RP
• Function of the thymus in HIV-infected adults.
  JAMA Volume: 282 Page(s): 219
  07/21/1999 Authors: Poulin JF; Skaly RP
• Understanding the mechanism of action of bacterial superantigens from a decade of research.
  Immunol Rev Volume: 168 Page(s): 257 - 269
  04/01/1999 Authors: Lavoie PM; Thibodeau J; Erard F; Skaly RP
• Role of the T cell receptor alpha chain in stabilizing TCR-superantigen-MHC class II complexes.
  Immunity Volume: 10 Page(s): 473 - 483
  04/01/1999 Authors: Andersen PS; Lavoie PM; Skaly RP; Churchill H; Kranz DM; Schlievert PM; Karjalainen K; Mariuzza RA
• Quantitation of thymic function using T cell receptor DNA deletion circles in isolated human peripheral blood lymphocytes.
  Volume: 103 Page(s): S212 - S212
  01/01/1999 Authors: Harris JM; Poulin JF; Komanduri K; Wieder E; Hanley MB; Bourbonniere M; Jenkins M; McCune JM; Sekaly RP
• Dynamics of naive CD4+ cells and CD4+, CD8+ TCR V beta repertoire in patients treated or not, during primary HIV infection (PHI).
  Volume: 92 Page(s): 168A - 168A
  11/15/1998 Authors: Routy JP; Ringuette N; Lacaille J; Savard S; Conway B; Sekaly RP
• Minimal tissue culture drug selection can reveal higher frequency of drug-resistant HIV in primary infection.
  Volume: 12 Page(s): S24 - S24
  11/01/1998 Authors: Wainberg MA; Salomon H; Oliveira M; Montaner JSG; Routy JP; Sekaly RP
• lck-independent inhibition of T cell antigen response by the HIV gp120.
  J Immunol Volume: 161 Page(s): 3551 - 3556
  10/01/1998 Authors: Gratton S; Julius M; Skaly RP
• lck-Independent inhibition of T cell antigen response by the HIV gp120
  JOURNAL OF IMMUNOLOGY Volume: 161 Page(s): 3551 - 3556
  10/01/1998 Authors: Gratton S; Julius M; Sekaly RP
• The role of caspases in T cell development and the control of immune responses.
  Cell Mol Life Sci Volume: 54 Page(s): 1005 - 1019
  09/01/1998 Authors: Denis F; Rhaume E; Aouad SM; Alam A; Skaly RP; Cohen LY
• Conserved structural features between HLA-DO beta and -DR beta.
  Mol Immunol Volume: 35 Page(s): 885 - 893
  09/01/1998 Authors: Thibodeau J; Lavoie PM; Samaan A; Corre JP; Skaly RP; Cazenave PA
• Induction of endogenous mammary tumor virus in lymphocytes infected with murine acquired immunodeficiency syndrome virus.
  Cell Immunol Volume: 187 Page(s): 124 - 130
  08/01/1998 Authors: Gayama S; Doyon L; Vaupel B; Sekaly RP; Kanagawa O
• Combination therapy for HIV: towards long term control of disease progression.
  Expert Opin Investig Drugs Volume: 7 Page(s): 941 - 961
  06/01/1998 Authors: Conway B; Routy JP; Skaly RP
• A mutational analysis of the binding of staphylococcal enterotoxins B and C3 to the T cell receptor beta chain and major histocompatibility complex class II.
  J Exp Med Volume: 187 Page(s): 823 - 833
  03/16/1998 Authors: Leder L; Llera A; Lavoie PM; Lebedeva MI; Li H; Skaly RP; Bohach GA; Gahr PJ; Schlievert PM; Karjalainen K
• Highly biased CDR3 usage in restricted sets of beta chain variable regions during viral superantigen 9 response.
  J Exp Med Volume: 187 Page(s): 253 - 258
  01/19/1998 Authors: Ciurli C; Posnett DN; Skaly RP; Denis F
• Staphylococcal enterotoxin D is a promiscuous superantigen offering multiple modes of interactions with the MHC class II receptors.
  J Immunol Volume: 160 Page(s): 225 - 232
  01/01/1998 Authors: Al-Daccak R; Mehindate K; Damdoumi F; Etongu-Mayer P; Nilsson H; Antonsson P; Sundstrm M; Dohlsten M; Skaly RP; Mourad W
• Quantitative aspects of T cell activation and death triggered by superantigens
  Page(s): 367 - 371
  01/01/1998 Authors: Lavoie PM; Thibodeau J; McGrath H; Sekaly RP
• Accumulation of human immunodeficiency virus-specific cytotoxic T lymphocytes away from the predominant site of virus replication during primary infection.
  Eur J Immunol Volume: 27 Page(s): 3166 - 3173
  12/01/1997 Authors: Pantaleo G; Soudeyns H; Demarest JF; Vaccarezza M; Graziosi C; Paolucci S; Daucher MB; Cohen OJ; Denis F; Biddison WE
• A mutation of F47 to A in staphylococcus enterotoxin A activates the T-cell receptor Vbeta repertoire in vivo.
  Infect Immun Volume: 65 Page(s): 5118 - 5124
  12/01/1997 Authors: Rosendahl A; Hansson J; Antonsson P; Skaly RP; Kalland T; Dohlsten M
• Specific activation of the cysteine protease CPP32 during the negative selection of T cells in the thymus.
  J Exp Med Volume: 186 Page(s): 1503 - 1512
  11/03/1997 Authors: Alam A; Braun MY; Hartgers F; Lesage S; Cohen L; Hugo P; Denis F; Skaly RP
• The large subunit of replication factor C is a substrate for caspase-3 in vitro and is cleaved by a caspase-3-like protease during Fas-mediated apoptosis.
  EMBO J Volume: 16 Page(s): 6346 - 6354
  11/03/1997 Authors: Rhaume E; Cohen LY; Uhlmann F; Lazure C; Alam A; Hurwitz J; Skaly RP; Denis F
• The processing routes determined by negatively charged residues in DR1-restricted T cell determinants.
  J Immunol Volume: 159 Page(s): 3238 - 3246
  10/01/1997 Authors: Robadey C; Ammerlaan W; Muller C; Cloutier I; Skaly RP; Haefliger JA; Demotz S
• Evidence for rapid disappearance of initially expanded HIV-specific CD8+ T cell clones during primary HIV infection.
  Proc Natl Acad Sci U S A Volume: 94 Page(s): 9848 - 9853
  09/02/1997 Authors: Pantaleo G; Soudeyns H; Demarest JF; Vaccarezza M; Graziosi C; Paolucci S; Daucher M; Cohen OJ; Denis F; Biddison WE
• Selective binding of bacterial toxins to major histocompatibility complex class II-expressing cells is controlled by invariant chain and HLA-DM.
  Proc Natl Acad Sci U S A Volume: 94 Page(s): 6892 - 6897
  06/24/1997 Authors: Lavoie PM; Thibodeau J; Cloutier I; Busch R; Skaly RP
• MHC class II-dependent peptide antigen versus superantigen presentation to T cells.
  Hum Immunol Volume: 54 Page(s): 194 - 201
  05/01/1997 Authors: Shoukry NH; Lavoie PM; Thibodeau J; D'Souza S; Sekaly RP
• Molecular characterization and role in T cell activation of staphylococcal enterotoxin A binding to the HLA-DR alpha-chain.
  J Immunol Volume: 158 Page(s): 3698 - 3704
  04/15/1997 Authors: Thibodeau J; Dohlsten M; Cloutier I; Lavoie PM; Bjork P; Michel F; Lveill C; Mourad W; Kalland T; Skaly RP
• Paracrine transfer of mouse mammary tumor virus superantigen.
  J Exp Med Volume: 185 Page(s): 471 - 480
  02/03/1997 Authors: Delcourt M; Thibodeau J; Denis F; Sekaly RP
• Superantigen-mediated deletion of specific T cell receptor V beta subsets in the SCID-hu Thy/Liv mouse is induced by staphylococcal enterotoxin B, but not HIV-1.
  J Immunol Volume: 158 Page(s): 544 - 549
  01/15/1997 Authors: Komanduri KV; Salha MD; Skaly RP; McCune JM
• The qualitative nature of the primary immune response to HIV infection is a prognosticator of disease progression independent of the initial level of plasma viremia.
  Proc Natl Acad Sci U S A Volume: 94 Page(s): 254 - 258
  01/07/1997 Authors: Pantaleo G; Demarest JF; Schacker T; Vaccarezza M; Cohen OJ; Daucher M; Graziosi C; Schnittman SS; Quinn TC; Shaw GM
• Analysis of the contact sites on the CD4 molecule with class II MHC molecule: co-ligand versus co-receptor function.
  J Immunol Volume: 158 Page(s): 216 - 225
  01/01/1997 Authors: Huang B; Yachou A; Fleury S; Hendrickson WA; Sekaly RP
• V alpha domain modulates the multiple topologies of mouse T cell receptor V beta20/staphylococcal enterotoxins A and E complexes.
  Eur J Immunol Volume: 27 Page(s): 92 - 99
  01/01/1997 Authors: Bravo de Alba Y; Marche PN; Cazenave PA; Cloutier I; Sekaly RP; Thibodeau J
• Molecular analysis of the cytoplasmic domain of CD4: overlapping but noncompetitive requirement for lck association and down-regulation by Nef.
  J Immunol Volume: 157 Page(s): 3305 - 3311
  10/15/1996 Authors: Gratton S; Yao XJ; Venkatesan S; Cohen EA; Skaly RP
• TCR binding differs for a bacterial superantigen (SEE) and a viral superantigen (Mtv-9).
  J Exp Med Volume: 184 Page(s): 1471 - 1482
  10/01/1996 Authors: Liao L; Marinescu A; Molano A; Ciurli C; Sekaly RP; Fraser JD; Popowicz A; Posnett DN
• Presence in peripheral blood of healthy individuals of autoreactive T cells to a membrane antigen present on bone marrow-derived cells.
  Blood Volume: 88 Page(s): 2144 - 2150
  09/15/1996 Authors: Filion MC; Proulx C; Bradley AJ; Devine DV; Skaly RP; Dcary F; Chartrand P
• An Epstein-Barr virus-associated superantigen.
  J Exp Med Volume: 184 Page(s): 971 - 980
  09/01/1996 Authors: Sutkowski N; Palkama T; Ciurli C; Sekaly RP; Thorley-Lawson DA; Huber BT
• An activated epidermal growth factor receptor/Lck chimera restores early T cell receptor-mediated calcium response in a CD45-deficient T cell line.
  J Biol Chem Volume: 271 Page(s): 17896 - 17902
  07/26/1996 Authors: Duplay P; Alcover A; Fargeas C; Skaly RP; Branton PE
• Repression of human immunodeficiency virus type 1 long terminal repeat-driven gene expression by binding of the virus to its primary cellular receptor, the CD4 molecule.
  J Virol Volume: 70 Page(s): 4009 - 4016
  06/01/1996 Authors: Brub P; Barbeau B; Cantin R; Skaly RP; Tremblay M
• T-cell receptor V beta-specific expansions in children from HIV-infected mothers.
  AIDS Volume: 10 Page(s): 549 - 551
  05/01/1996 Authors: Silvestri G; Soudeyns H; Samson J; Denis F; Lapointe N; Skaly RP
• Mutations in human CD4 impair the functional interaction with different human and mouse class II isotypes and alleles.
  J Immunol Volume: 156 Page(s): 1848 - 1855
  03/01/1996 Authors: Fleury S; Huang B; Zerbib A; Croteau G; Long EO; Sekaly RP
• Differential recognition by CD28 of its cognate counter receptors CD80 (B7.1) and B70 (B7.2): analysis by site directed mutagenesis.
  Mol Immunol Volume: 33 Page(s): 321 - 334
  02/01/1996 Authors: Truneh A; Reddy M; Ryan P; Lyn SD; Eichman C; Couez D; Hurle MR; Sekaly RP; Olive D; Sweet R
• Invariant chain protects class II histocompatibility antigens from binding intact polypeptides in the endoplasmic reticulum.
  EMBO J Volume: 15 Page(s): 418 - 428
  01/15/1996 Authors: Busch R; Cloutier I; Skaly RP; Hmmerling GJ
• Analysis of CD28 interactions with its cognate counterreceptors CD80 and CD86.
  Volume: 95 Page(s): 3 - 19
  01/01/1996 Authors: Truneh A; Reddy M; Ryan P; Lyn SD; Kariv I; Eichman C; Couez D; Hurle MR; Sekaly RP; Olive D
• Evidence that the murine AIDS defective virus does not encode a superantigen.
  J Virol Volume: 70 Page(s): 1 - 9
  01/01/1996 Authors: Doyon L; Simard C; Skaly RP; Jolicoeur P
• Study of the T cell receptor repertoire in viral immunodeficiency disease.
  Springer Semin Immunopathol Volume: 17 Page(s): 319 - 332
  01/01/1996 Authors: Ciurli C; Skaly RP; Soudeyns H
• Cross-linking of major histocompatibility complex class II molecules by staphylococcal enterotoxin A superantigen is a requirement for inflammatory cytokine gene expression.
  J Exp Med Volume: 182 Page(s): 1573 - 1577
  11/01/1995 Authors: Mehindate K; Thibodeau J; Dohlsten M; Kalland T; Skaly RP; Mourad W
• Identification of residues in the V domain of CD80 (B7-1) implicated in functional interactions with CD28 and CTLA4.
  J Exp Med Volume: 182 Page(s): 667 - 675
  09/01/1995 Authors: Fargeas CA; Truneh A; Reddy M; Hurle M; Sweet R; Skaly RP
• HLA-DR polymorphism affects the interaction with CD4.
  J Exp Med Volume: 182 Page(s): 733 - 741
  09/01/1995 Authors: Fleury S; Thibodeau J; Croteau G; Labrecque N; Aronson HE; Cantin C; Long EO; Skaly RP
• Degradation of CD4 induced by human immunodeficiency virus type 1 Vpu protein: a predicted alpha-helix structure in the proximal cytoplasmic region of CD4 contributes to Vpu sensitivity.
  Virology Volume: 209 Page(s): 615 - 623
  06/01/1995 Authors: Yao XJ; Friborg J; Checroune F; Gratton S; Boisvert F; Skaly RP; Cohen EA
• A MINORITY OF HLA-DR1 MOLECULES AT THE CELL-SURFACE CAN BIND SUPERANTIGENS
  Volume: 9 Page(s): A1059 - A1059
  03/10/1995 Authors: THIBODEAU T; LEVEILLEE C; CLOUTIER I; LEROUX JY; MOURAD W; SEKALY RP
• HLA-DR POLYMORPHISM AFFECTS THE INTERACTION WITH CD4
  Volume: 9 Page(s): A1055 - A1055
  03/10/1995 Authors: SEKALY RP; THIBODEAU J; CROTEAU G; LABRECQUE N; ARONSON HE; CANTIN C; LONG EO; FLEURY S
• MAPPING AND DISCRIMINATION OF THE INTERACTION OF THE HUMAN B7 RECEPTORS B7.1 AND B7.2 WITH HUMAN CD28
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  03/10/1995 Authors: TRUNEH A; REDDY M; RYAN P; COUEZ D; SEKALY R; OLIVE D; SWEET R
• PRIMARY IMMUNE-RESPONSE TO HIV-INFECTION
  Volume: 11 Page(s): S149 - S149
  01/01/1995 Authors: PANTALEO G; DEMAREST JF; VACCAREZZA M; DAUCHER M; GRAZIOSI C; COHEN OC; SCHNITTMANN SM; PERIN L; TAMBUSS G; SHAW GM
• Subsets of HLA-DR1 molecules defined by SEB and TSST-1 binding.
  Science Volume: 266 Page(s): 1874 - 1878
  12/16/1994 Authors: Thibodeau J; Cloutier I; Lavoie PM; Labrecque N; Mourad W; Jardetzky T; Skaly RP
• T cell receptor-major histocompatibility complex class II interaction is required for the T cell response to bacterial superantigens.
  J Exp Med Volume: 180 Page(s): 1921 - 1929
  11/01/1994 Authors: Labrecque N; Thibodeau J; Mourad W; Skaly RP
• Major expansion of CD8+ T cells with a predominant V beta usage during the primary immune response to HIV.
  Nature Volume: 370 Page(s): 463 - 467
  08/11/1994 Authors: Pantaleo G; Demarest JF; Soudeyns H; Graziosi C; Denis F; Adelsberger JW; Borrow P; Saag MS; Shaw GM; Sekaly RP
• Insulin binding to human cultured lymphocytes measured by flow cytometry using three ligands.
  Cytometry Volume: 16 Page(s): 339 - 345
  08/01/1994 Authors: Ziegler O; Cantin C; Germain L; Dupuis M; Sekaly RP; Drouin P; Chiasson JL
• Lack of evidence for the dichotomy of TH1 and TH2 predominance in HIV-infected individuals.
  Science Volume: 265 Page(s): 248 - 252
  07/08/1994 Authors: Graziosi C; Pantaleo G; Gantt KR; Fortin JP; Demarest JF; Cohen OJ; Skaly RP; Fauci AS
• LFA-1-mediated antigen-independent T cell adhesion is regulated by CD4 and p56lck tyrosine kinase.
  J Immunol Volume: 152 Page(s): 5670 - 5679
  06/15/1994 Authors: Mazerolles F; Barbat C; Meloche S; Gratton S; Soula M; Fagard R; Fischer S; Hivroz C; Bernier J; Sekaly RP
• CD4-mediated enhancement or inhibition of T cell activation does not require the CD4:p56lck association.
  J Exp Med Volume: 179 Page(s): 1973 - 1983
  06/01/1994 Authors: Zerbib AC; Reske-Kunz AB; Lock P; Skaly RP
• Molecular analysis of antigen-independent adhesion forces between T and B lymphocytes.
  Proc Natl Acad Sci U S A Volume: 91 Page(s): 3628 - 3632
  04/26/1994 Authors: Amblard F; Auffray C; Sekaly R; Fischer A
• Comparative analysis of the T cell receptor V beta repertoire in various lymphoid tissues from HIV-infected patients: evidence for an HIV-associated superantigen.
  Volume: 8 Suppl 1 Page(s): S95 - S97
  04/01/1994 Authors: Soudeyns H; Routy JP; Skaly RP
• Binding sites for bacterial and endogenous retroviral superantigens can be dissociated on major histocompatibility complex class II molecules.
  J Exp Med Volume: 179 Page(s): 1029 - 1034
  03/01/1994 Authors: Thibodeau J; Labrecque N; Denis F; Huber BT; Skaly RP
• Association of p56lck with the cytoplasmic domain of CD4 modulates HIV-1 expression.
  EMBO J Volume: 13 Page(s): 774 - 783
  02/15/1994 Authors: Tremblay M; Meloche S; Gratton S; Wainberg MA; Skaly RP
• Analysis of the T-cell receptor beta-chain variable-region (V beta) repertoire in monozygotic twins discordant for human immunodeficiency virus: evidence for perturbations of specific V beta segments in CD4+ T cells of the virus-positive twins.
  Proc Natl Acad Sci U S A Volume: 91 Page(s): 1529 - 1533
  02/15/1994 Authors: Rebai N; Pantaleo G; Demarest JF; Ciurli C; Soudeyns H; Adelsberger JW; Vaccarezza M; Walker RE; Sekaly RP; Fauci AS
• Early expression of human CD4 delays thymic differentiation in transgenic mice.
  Res Immunol Volume: 145 Page(s): 5 - 16
  01/01/1994 Authors: Doyon L; Hanna Z; Jolicoeur P; Skaly RP
• CORECEPTOR AND CO-LIGAND FUNCTION OF CD4 INVOLVE DIFFERENT SITES ON CD4 AND ON MHC CLASS-II MOLECULES
  Page(s): 346 - 346
  01/01/1994 Authors: SEKALY RP; HUANG B; FLEURY S; YACHOU A; ARONSON HE; HENDRICKSON W; THIBODEAU J
• SEPARABLE BINDING-SITES FOR BACTERIAL AND ENDOGENOUS RETROVIRAL SUPERANTIGENS ON MHC CLASS-II MOLECULES
  Page(s): 369 - 369
  01/01/1994 Authors: THIBODEAU J; LABRECQUE N; DENIS F; HUBER BT; SEKALY RP
• THE EXTRACELLULAR DOMAIN OF CD4 REGULATES THE INITIATION OF T-CELL ACTIVATION IN A CIS MANNER
  Page(s): 401 - 401
  01/01/1994 Authors: GRATTON S; HAUGHN L; JULIUS M; SEKALY RP
• Presentation of the Mls-1 superantigen by human HLA class II molecules to murine T cells.
  J Immunol Volume: 151 Page(s): 2538 - 2545
  09/01/1993 Authors: Subramanyam M; McLellan B; Labrecque N; Sekaly RP; Huber BT
• Amyloid precursor protein in peripheral mononuclear cells is up-regulated with cell activation.
  J Immunol Volume: 150 Page(s): 5566 - 5575
  06/15/1993 Authors: Ledoux S; Rebai N; Dagenais A; Shaw IT; Nalbantoglu J; Sekaly RP; Cashman NR
• The T cell receptor V beta repertoire in HIV-1 infection and disease.
  Semin Immunol Volume: 5 Page(s): 175 - 185
  06/01/1993 Authors: Soudeyns H; Rebai N; Pantaleo GP; Ciurli C; Boghossian T; Skaly RP; Fauci AS
• BACTERIAL SUPERANTIGENS - PATHOGENIC AGENTS OR THERAPEUTIC TOOLS (VOL 9, PG 605, 1993)
  M S-MEDECINE SCIENCES Volume: 9 Page(s): 724 - 724
  06/01/1993 Authors: THIBODEAU J; CROTEAU G; LABRECQUE N; SEKALY RP
• Human T cells respond to mouse mammary tumor virus-encoded superantigen: V beta restriction and conserved evolutionary features.
  J Exp Med Volume: 177 Page(s): 1735 - 1743
  06/01/1993 Authors: Labrecque N; McGrath H; Subramanyam M; Huber BT; Skaly RP
• V-BETA-SPECIFIC VARIATIONS IN THE TCR REPERTOIRE OF HIV-INFECTED SUBJECTS SUGGEST THE PRESENCE OF AN HIV-ASSOCIATED SUPERANTIGEN
  Volume: 150 Page(s): A104 - A104
  04/15/1993 Authors: SOUDEYNS H; PANTALEO GP; BOGHOSSIAN T; CIURLI C; REBAI N; LANE HC; FAUCI AS; SEKALY RP
• POLYMORPHISM IN THE BETA-CHAIN OF HLA-DR AFFECTS THE INTERACTION WITH CD4
  Volume: 150 Page(s): A288 - A288
  04/15/1993 Authors: THIBODEAU J; FLEURY S; LABRECQUE N; CANTIN C; ARONSON HE; HENDRICKSON W; YACHOU A; LONG E; SEKALY RP
• V-BETA-SPECIFIC VARIATIONS IN THE T-CELL RECEPTOR REPERTOIRE OF HIV-INFECTED SUBJECTS SUGGEST THE PRESENCE OF AN HIV-ASSOCIATED SUPERANTIGEN
  Page(s): 71 - 71
  03/29/1993 Authors: SOUDEYNS H; PANTALEO GP; BOGHOSSIAN T; CIURLI C; REBAI N; LANE HC; FAUCI AS; SEKALY RP
• Pentosan polysulfate, a potent anti HIV and anti tumor agent, inhibits protein serine/threonine and tyrosine kinases.
  Mol Cell Biochem Volume: 120 Page(s): 127 - 133
  03/24/1993 Authors: Srivastava AK; Skaly RP; Chiasson JL
• HUMAN T-CELL RESPONSE TO MTV7 SUPERANTIGEN
  Page(s): 51 - 51
  03/13/1993 Authors: LABRECQUE N; MCGRATH H; SUBRAMANYAM M; HUBER BT; SEKALY RP
• Human immunodeficiency virus gp120 and derived peptides activate protein tyrosine kinase p56lck in human CD4 T lymphocytes.
  Eur J Immunol Volume: 23 Page(s): 600 - 607
  03/01/1993 Authors: Hivroz C; Mazerolles F; Soula M; Fagard R; Graton S; Meloche S; Sekaly RP; Fischer A
• 49TH FORUM IN IMMUNOLOGY - T-CELL RECOGNITION OF SUPERANTIGENS - DISCUSSION
  RESEARCH IN IMMUNOLOGY Volume: 144 Page(s): 214 - 222
  03/01/1993 Authors: LABRECQUE N; THIBODEAU J; SEKALY RP; KARP DR; GASCOIGNE NRJ; FRASER JD; HUDSON KR; SIMPSON E; ACHAORBEA H; WOODLAND DL
• INTERSPECIES SPECIFIC INTERACTIONS BETWEEN HUMAN AND MURINE-CD4 AND MHC CLASS-II ISOTYPES AND ALLELES
  Page(s): 78 - 78
  02/08/1993 Authors: FLEURY S; CROTEAU G; HENDRICKSON WA; SEKALY RP
• Interactions between staphylococcal superantigens and MHC class II molecules.
  Semin Immunol Volume: 5 Page(s): 23 - 32
  02/01/1993 Authors: Labrecque N; Thibodeau J; Skaly RP
• HUMAN T-CELL RESPONSE TO RETROVIRALLY ENCODED SUPERANTIGENS
  Page(s): 132 - 132
  01/26/1993 Authors: HUBER BT; SUBRAMANYAM M; MCLELLAN B; LABRECQUE N; SEKALY RP
• T-cell receptor recognition of superantigens: another view.
  Res Immunol Volume: 144 Page(s): 175 - 180
  01/01/1993 Authors: Labrecque N; Thibodeau J; Skaly RP
• Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis.
  J Exp Med Volume: 176 Page(s): 1099 - 1106
  10/01/1992 Authors: Banda NK; Bernier J; Kurahara DK; Kurrle R; Haigwood N; Sekaly RP; Finkel TH
• A viral long terminal repeat expressed in CD4+CD8+ precursors is downregulated in mature peripheral CD4-CD8+ or CD4+CD8- T cells.
  Mol Cell Biol Volume: 12 Page(s): 3522 - 3530
  08/01/1992 Authors: Paquette Y; Doyon L; Laperrire A; Hanna Z; Ball J; Sekaly RP; Jolicoeur P
• Association of tyrosine kinase p56lck with CD4 inhibits the induction of growth through the alpha beta T-cell receptor.
  Nature Volume: 358 Page(s): 328 - 331
  07/23/1992 Authors: Haughn L; Gratton S; Caron L; Skaly RP; Veillette A; Julius M
• Accelerated entry of aortic smooth muscle cells from spontaneously hypertensive rats into the S phase of the cell cycle.
  Biochem Cell Biol Volume: 70 Page(s): 599 - 604
  07/01/1992 Authors: Hadrava V; Tremblay J; Sekaly RP; Hamet P
• PERTURBATION OF THE T-CELL RECEPTOR V-BETA REPERTOIRE IN PERIPHERAL-BLOOD T-CELLS OF HIV INFECTED INDIVIDUALS
  Volume: 40 Page(s): A253 - A253
  04/01/1992 Authors: PANTALEO G; TREBAI N; GRAZIOSI C; LANE HC; SEKALY RP; FAUCI AS
• INHIBITORY EFFECT OF PENTOSAN POLYSULFATE - A POTENT ANTI HIV AND ANTI TUMOR AGENT ON PROTEIN SERINE/THREONINE AND TYROSINE KINASES
  Volume: 6 Page(s): A1851 - A1851
  02/28/1992 Authors: CHIASSON JC; SEKALY RP; CHIASSON JL; SRIVASTAVA AK
• PENTOSAN POLYSULFATE, A POTENT ANTI-HIV AND ANTITUMOR GROWTH AGENT, INHIBITS PROTEIN SERINE THREONINE AND TYROSINE KINASES
  Volume: 51 Page(s): 144 - 144
  02/01/1992 Authors: SRIVASTAVA AK; CHIASSON JC; SEKALY RP; CHIASSON JL
• New chamber for flow cytometric analysis over an extended range of stream velocity and application to cell adhesion measurements.
  Cytometry Volume: 13 Page(s): 15 - 22
  01/01/1992 Authors: Amblard F; Cantin C; Durand J; Fischer A; Skaly R; Auffray C
• Structural aspects of CD4 and CD8 involvement in the cellular immune response.
  Volume: 57 Page(s): 549 - 556
  01/01/1992 Authors: Hendrickson WA; Kwong PD; Leahy DJ; Ryu SE; Yamaguchi H; Fleury S; Skaly RP
• Identification of the staphylococcal enterotoxin A superantigen binding site in the beta 1 domain of the human histocompatibility antigen HLA-DR.
  Proc Natl Acad Sci U S A Volume: 88 Page(s): 9954 - 9958
  11/15/1991 Authors: Herman A; Labrecque N; Thibodeau J; Marrack P; Kappler JW; Sekaly RP
• Mutational analysis of the interaction between CD4 and class II MHC: class II antigens contact CD4 on a surface opposite the gp120-binding site.
  Cell Volume: 66 Page(s): 1037 - 1049
  09/06/1991 Authors: Fleury S; Lamarre D; Meloche S; Ryu SE; Cantin C; Hendrickson WA; Sekaly RP
• Efficient cDNA expression vectors for stable and transient expression of HLA-DR in transfected fibroblast and lymphoid cells.
  Hum Immunol Volume: 31 Page(s): 229 - 235
  08/01/1991 Authors: Long EO; Rosen-Bronson S; Karp DR; Malnati M; Sekaly RP; Jaraquemada D
• Direct involvement of CD7 (gp40) in activation of TcR gamma/delta+ T cells.
  Eur J Immunol Volume: 21 Page(s): 1195 - 1200
  05/01/1991 Authors: Carrel S; Salvi S; Rafti F; Favrot M; Rapin C; Sekaly RP
• CD4 and CD8 recognition of class II and class I molecules of the major histocompatibility complex.
  Semin Immunol Volume: 3 Page(s): 177 - 185
  05/01/1991 Authors: Fleury SG; Croteau G; Skaly RP
• Characterization of a monoclonal antibody directed against the phosphotyrosine kinase p56lck, in human T cells.
  Scand J Immunol Volume: 33 Page(s): 375 - 380
  04/01/1991 Authors: Ansotegui IJ; Chow SC; Jeddi-Tehrani M; Meloche S; Pawson A; Sekaly RP; Mak TW; Wigzell H
• Activated CD3- CD16+ natural killer cells express a subset of the lymphokine genes induced in activated alpha beta + and gamma delta + T cells.
  Scand J Immunol Volume: 33 Page(s): 247 - 252
  03/01/1991 Authors: Biassoni R; Ferrini S; Prigione I; Pelak VS; Sekaly RP; Long EO
• Positive signal transduction via surface CD4 molecules does not need coexpression of the CD3/TcR complex.
  Res Immunol Volume: 142 Page(s): 97 - 108
  02/01/1991 Authors: Carrel S; Salvi S; Gallay P; Rapin C; Sekaly RP
• The CD4 molecule is not always required for the T cell response to bacterial enterotoxins.
  J Exp Med Volume: 173 Page(s): 367 - 371
  02/01/1991 Authors: Skaly RP; Croteau G; Bowman M; Scholl P; Burakoff S; Geha RS
• A SIGNAL MEDIATED VIA THE CYTOPLASMIC DOMAIN OF THE CD4 MOLECULE INFLUENCES THE LEVEL OF HIV-1 REPLICATION
  Volume: 4 Page(s): 329 - 329
  01/01/1991 Authors: TREMBLAY M; MELOCHE S; WAINBERG MA; SEKALY RP
• HLA-DR alleles differ in their ability to present staphylococcal enterotoxins to T cells.
  J Exp Med Volume: 172 Page(s): 709 - 717
  09/01/1990 Authors: Herman A; Croteau G; Sekaly RP; Kappler J; Marrack P
• Binding of toxic shock syndrome toxin-1 to murine major histocompatibility complex class II molecules.
  Eur J Immunol Volume: 20 Page(s): 1911 - 1916
  09/01/1990 Authors: Scholl PR; Sekaly RP; Diez A; Glimcher LH; Geha RS
• Complement receptor 2 mediates enhancement of human immunodeficiency virus 1 infection in Epstein-Barr virus-carrying B cells.
  J Exp Med Volume: 171 Page(s): 1791 - 1796
  05/01/1990 Authors: Tremblay M; Meloche S; Sekaly RP; Wainberg MA
• Expression and function of the transfected CD8 alpha chain in murine T cell hybridomas.
  Int Immunol Volume: 2 Page(s): 957 - 964
  01/01/1990 Authors: Kanagawa O; Nakauchi H; Sekaly RP; Maeda K; Takagaki Y
• Cell surface expression of hybrid murine/human MHC class II beta alpha dimers. Key influence of residues in the amino-terminal portion of the beta 1 domain.
  J Immunol Volume: 144 Page(s): 329 - 333
  01/01/1990 Authors: Lechler RI; Sant AJ; Braunstein NS; Sekaly R; Long E; Germain RN
• Effect of isotypes and allelic polymorphism on the binding of staphylococcal exotoxins to MHC class II molecules.
  J Immunol Volume: 144 Page(s): 226 - 230
  01/01/1990 Authors: Scholl PR; Diez A; Karr R; Sekaly RP; Trowsdale J; Geha RS
• Class II MHC molecules and the HIV gp 120 envelope protein interact with functionally distinct regions of the CD4 molecule.
  EMBO J Volume: 8 Page(s): 3271 - 3277
  11/01/1989 Authors: Lamarre D; Capon DJ; Karp DR; Gregory T; Long EO; Skaly RP
• Transcription of unrearranged T cell receptor delta genes in CD3- major histocompatibility complex-unrestricted cytotoxic cells.
  Eur J Immunol Volume: 19 Page(s): 1973 - 1976
  10/01/1989 Authors: Biassoni R; Ferrini S; Sekaly RP; Long EO
• The MHC-binding and gp120-binding functions of CD4 are separable.
  Science Volume: 245 Page(s): 743 - 746
  08/18/1989 Authors: Lamarre D; Ashkenazi A; Fleury S; Smith DH; Sekaly RP; Capon DJ
• HLA class II-restricted presentation of cytoplasmic measles virus antigens to cytotoxic T cells.
  J Virol Volume: 63 Page(s): 1756 - 1762
  04/01/1989 Authors: Jacobson S; Sekaly RP; Jacobson CL; McFarland HF; Long EO
• A positive signal is transduced via surface CD4 molecules.
  Res Immunol Volume: 140 Page(s): 545 - 561
  01/01/1989 Authors: Carrel S; Lamarre D; Isler P; Rapin C; Fleury S; Salvi S; Sekaly RP; Cerottini JC
• Structural and functional studies of HLA-DR restricted antigen recognition by human helper T lymphocyte clones by using transfected murine cell lines.
  J Immunol Volume: 141 Page(s): 3003 - 3009
  11/01/1988 Authors: Lechler RI; Bal V; Rothbard JB; Germain RN; Sekaly R; Long EO; Lamb J
• MAJOR HISTOCOMPATIBILITY ANTIGEN EXPRESSION BY GLIAL-CELLS OF YOUNG-ADULTS
  Volume: 24 Page(s): 167 - 167
  07/01/1988 Authors: RUIJS TCG; GRENIER Y; SEKALY R; OLIVIER A; ANTEL J
• Presentation of influenza hemagglutinin peptide in the presence of limited allostimulation by HLA-DR1 transfected human fibroblasts.
  Hum Immunol Volume: 21 Page(s): 173 - 181
  03/01/1988 Authors: Eckels DD; Sell TW; Long EO; Sekaly RP
• Structural model of HLA-DR1 restricted T cell antigen recognition.
  Cell Volume: 52 Page(s): 515 - 523
  02/26/1988 Authors: Rothbard JB; Lechler RI; Howland K; Bal V; Eckels DD; Sekaly R; Long EO; Taylor WR; Lamb JR
• Antigen presentation to HLA class II-restricted measles virus-specific T-cell clones can occur in the absence of the invariant chain.
  Proc Natl Acad Sci U S A Volume: 85 Page(s): 1209 - 1212
  02/01/1988 Authors: Sekaly RP; Jacobson S; Richert JR; Tonnelle C; McFarland HF; Long EO
• Recognition of intracellular measles virus antigens by HLA class II restricted measles virus-specific cytotoxic T lymphocytes.
  Ann N Y Acad Sci Volume: 540 Page(s): 352 - 353
  01/01/1988 Authors: Jacobson S; Sekaly RP; Bellini WJ; Johnson CL; McFarland HF; Long EO
• RECOGNITION OF INTRACELLULAR MEASLES-VIRUS ANTIGENS BY HLA CLASS-II-RESTRICTED MEASLES VIRUS-SPECIFIC CYTOTOXIC LYMPHOCYTES-T
  Volume: 16 Page(s): 83 - 83
  09/01/1987 Authors: JACOBSON S; SEKALY RP; BELLINI WJ; JOHNSON CL; MCFARLAND HF; LONG EO
• Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen.
  Nature Volume: 328 Page(s): 626 - 629
  08/13/1987 Authors: Gay D; Maddon P; Sekaly R; Talle MA; Godfrey M; Long E; Goldstein G; Chess L; Axel R; Kappler J
• Characterization of CD3+, CD4-, CD8- clones expressing the putative T cell receptor gamma gene product. Analysis of the activation pathways leading to interleukin 2 production and triggering of the lytic machinery.
  J Exp Med Volume: 166 Page(s): 277 - 282
  07/01/1987 Authors: Ferrini S; Bottino C; Biassoni R; Poggi A; Sekaly RP; Moretta L; Moretta A
• FURTHER DIVERSITY IN HUMAN CLASS-II ANTIGENS MAY BE GENERATED BY ISOTYPICALLY-MIXED ALPHA-BETA PAIRS
  Volume: 46 Page(s): 1197 - 1197
  03/05/1987 Authors: SEKALY RP; LONG EO
• FUNCTIONAL INTERACTION BETWEEN HLA CLASS II ANTIGENS AND THE T4 MOLECULE
  Volume: 46 Page(s): 1051 - 1051
  03/01/1987 Authors: LEE C; SEKALY RP; GAY D; MADDON P; AXEL R; MARRACK P; LONG EO
• PRESENTATION OF MEASLES-VIRUS TO DR1-RESTRICTED CTL CAN OCCUR IN ABSENCE OF THE INVARIANT CHAIN
  Page(s): 290 - 290
  01/01/1987 Authors: SEKALY RP; JACOBSON S; LONG EO
• Cell surface expression of class II histocompatibility antigens occurs in the absence of the invariant chain.
  J Exp Med Volume: 164 Page(s): 1490 - 1504
  11/01/1986 Authors: Sekaly RP; Tonnelle C; Strubin M; Mach B; Long EO
• THE TRANSACTIVATOR (TAT) GENE OF THE HUMAN T-LYMPHOTROPIC VIRUS-TYPE-II (HTLV-II) INDUCES INTERLEUKIN-2 RECEPTOR, INTERLEUKIN-2, AND IA CELLULAR GENE-EXPRESSION
  Volume: 34 Page(s): A669 - A669
  04/01/1986 Authors: GREENE WC; LEONARD WJ; WANO Y; SEKALY RP; LONG EO; SODROSKI JG; ROSEN CA; HASELTINE WA
• TRANSIENT AND STABLE EXPRESSION OF HUMAN CLASS-II HISTOCOMPATIBILITY ANTIGENS IN CELLS TRANSFECTED WITH CDNA CLONES
  Page(s): 145 - 145
  01/01/1986 Authors: LONG EO; SEKALY R
• Early hemopoietic progenitor cells: direct measurement of cell cycle status.
  Ann N Y Acad Sci Volume: 459 Page(s): 150 - 161
  01/01/1985 Authors: Cillo C; Sekaly RP; Magli MC; Odartchenko N
• Regulation of the rate of cell cycle progression in quiescent cytolytic T cells by T cell growth factor: analysis by flow microfluorometry.
  J Cell Physiol Volume: 121 Page(s): 159 - 166
  10/01/1984 Authors: Sekaly RP; MacDonald HR; Nabholz M; Smith KA; Cerottini JC
• Monoclonal antibody against a "Pan-T-cell" antigen expressed by thymocytes, peripheral T-lymphocytes and T-cell leukemias.
  Mol Immunol Volume: 21 Page(s): 831 - 840
  10/01/1984 Authors: Carrel S; Gross N; Heumann D; Sekaly RP; Girardet C; Schmidt-Kessen A; Mach JP
• Target cell susceptibility to immune lysis and expression of MHC antigens are independent of position in the cell cycle.
  J Immunol Volume: 133 Page(s): 40 - 44
  07/01/1984 Authors: Harris DT; Sekaly RP
• Generation of thymocyte subpopulations in organ culture: correlated analysis of Lyt-2 phenotype and cell cycle status by flow microfluorometry.
  J Immunol Volume: 131 Page(s): 1085 - 1089
  09/01/1983 Authors: Skaly RP; Ceredig R; MacDonald HR
• Differentiation in vitro of Lyt 2+ thymocytes from embryonic Lyt 2- precursors.
  Nature Volume: 303 Page(s): 248 - 250
  05/19/1983 Authors: Ceredig R; Sekaly RP; MacDonald HR
• Characterization of a monoclonal antibody (A12) that defines a human acute lymphoblastic leukemia-associated differentiation antigen.
  Hybridoma Volume: 2 Page(s): 149 - 160
  01/01/1983 Authors: Carrel S; Heumann D; Sekaly RP; Zaech P; Buchegger F; Girardet C
• Correlated expression of T cell growth factor dependence, sensitivity to Vicia villosa lectin, and cytolytic activity in hybrids between cytolytic T cells and T lymphomas.
  J Exp Med Volume: 156 Page(s): 1335 - 1351
  11/01/1982 Authors: Conzelmann A; Silva A; Cianfriglia M; Tougne C; Sekaly RP; Nabholz M
• Cell cycle regulation of cloned cytolytic T cells by T cell growth factor: analysis by flow microfluorometry.
  J Immunol Volume: 129 Page(s): 1407 - 1414
  10/01/1982 Authors: Sekaly RP; MacDonald HR; Zaech P; Nabholz M
• High percentage of proliferating cells in a splenectomized patient with a B-prolymphocytic leukaemia.
  Br J Haematol Volume: 51 Page(s): 178 - 180
  05/01/1982 Authors: Schneider P; Delacrtaz F; Sekaly R; Cech P; Libanska C
• Cytolytic T lymphocyte clones.
  Immunobiology Volume: 161 Page(s): 84 - 106
  03/01/1982 Authors: MacDonald HR; Sekaly RP; Kanagawa O; Thiernesse N; Taswell C; Cerottini JC; Weiss A; Glasebrook AL; Engers HD; Kelso A
• Demonstration at the single-cell level of the existence of distinct clusters of epitopes in two predefined human Ia molecular subsets.
  Eur J Immunol Volume: 12 Page(s): 166 - 169
  02/01/1982 Authors: Accolla RS; Sekaly RP; McDonald AP; Corte G; Gross N; Carrel S
• PRECURSOR CELL-CYCLE IN MOUSE MARROW
  Volume: 38 Page(s): 738 - 738
  01/01/1982 Authors: CILLO C; SEKALY RP; ODARTCHENKO N
• Cytolytic T lymphocyte function is independent of growth phase and position in the mitotic cycle.
  J Exp Med Volume: 154 Page(s): 575 - 580
  08/01/1981 Authors: Sekaly RP; MacDonald HR; Zaech P; Glasebrook AL; Cerottini JC
• Phenotypic characterization of human cytolytic T lymphocytes in mixed lymphocyte culture.
  J Exp Med Volume: 153 Page(s): 213 - 218
  01/01/1981 Authors: Moretta A; Mingari MC; Haynes BF; Sekaly RP; Moretta L; Fauci AS
• CELL-CYCLE ANALYSIS OF T-CELL GROWTH-FACTOR DEPENDENT CYTOLYTIC CLONES
  Volume: 159 Page(s): 81 - 82
  01/01/1981 Authors: SEKALY RP; MACDONALD HR; NABHOLZ M; GLASEBROOK A; CEROTTINI JC