Mohamed Abdel-Hakeem
- Department of Pathology and Laboratory Medicine
Assistant Professor
-
Emory University School of Medicine
Department of Pathology and Laboratory Medicine
1462 Clifton Rd, Room 440B
Education
Degrees
- PhD from Université de Montréal
- MSc from Université de Montréal
- BPharm from Cairo University
Research
Publications
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CD8+ T cell-derived Fgl2 regulates immunity in a cell-autonomous manner via ligation of FcRIIB.
Nat Commun Volume: 15 Page(s): 5280
06/20/2024 Authors: Bennion KB; Liu D; Dawood AS; Wyatt MM; Alexander KL; Abdel-Hakeem MS; Paulos CM; Ford ML -
Coordinated expansion of memory T follicular helper and B cells mediates spontaneous clearance of HCV reinfection.
Front Immunol Volume: 15 Page(s): 1403769
01/01/2024 Authors: Eisa M; Gomez-Escobar E; Bdard N; Abdeltawab NF; Flores N; Mazouz S; Fieff-Bdard A; Sakayan P; Gridley J; Abdel-Hakeem MS -
Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ Tcells toward durable effector-like states during chronic antigen exposure.
Immunity Volume: 56 Page(s): 2699 - 2718.e11
12/12/2023 Authors: Beltra J-C; Abdel-Hakeem MS; Manne S; Zhang Z; Huang H; Kurachi M; Su L; Picton L; Ngiow SF; Muroyama Y -
Differential immune transcriptomic profiles between vaccinated and resolved HCV reinfected subjects.
PLoS Pathog Volume: 18 Page(s): e1010968
11/01/2022 Authors: Mazouz S; Salinas E; Bdard N; Filali A; Khedr O; Swadling L; Abdel-Hakeem MS; Siddique A; Barnes E; Bruneau J -
Shared and distinct biological circuits in effector, memory and exhausted CD8+ T cells revealed by temporal single-cell transcriptomics and epigenetics.
Nat Immunol Volume: 23 Page(s): 1600 - 1613
11/01/2022 Authors: Giles JR; Ngiow SF; Manne S; Baxter AE; Khan O; Wang P; Staupe R; Abdel-Hakeem MS; Huang H; Mathew D -
Identification of a Multi-Messenger RNA Signature as Type 2 Diabetes Mellitus Candidate Genes Involved in Crosstalk between Inflammation and Insulin Resistance.
Biomolecules Volume: 12
09/02/2022 Authors: Ali HS; Boshra MS; Agwa SHA; Hakeem MSA; Meteini MSE; Matboli M -
MicroRNA-29a attenuates CD8 T cell exhaustion and induces memory-like CD8 T cells during chronic infection.
Proc Natl Acad Sci U S A Volume: 119 Page(s): e2106083119
04/26/2022 Authors: Stelekati E; Cai Z; Manne S; Chen Z; Beltra J-C; Buchness LA; Leng X; Ristin S; Nzingha K; Ekshyyan V -
Editorial: T cell exhaustion; mechanisms of induction, modulation, and recovery.
Front Immunol Volume: 13 Page(s): 1122530
01/01/2022 Authors: Abdel-Hakeem MS -
Signaling Through FcRIIA and the C5a-C5aR Pathway Mediate Platelet Hyperactivation in COVID-19.
Front Immunol Volume: 13 Page(s): 834988
01/01/2022 Authors: Apostolidis SA; Sarkar A; Giannini HM; Goel RR; Mathew D; Suzuki A; Baxter AE; Greenplate AR; Alanio C; Abdel-Hakeem M -
Author Correction: Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation.
Nat Immunol Volume: 22 Page(s): 1465
11/01/2021 Authors: Abdel-Hakeem MS; Manne S; Beltra J-C; Stelekati E; Chen Z; Nzingha K; Ali M-A; Johnson JL; Giles JR; Mathew D