Publications

• Diverse priming outcomes under conditions of very rare precursor B cells.
  Immunity Volume: 58 Page(s): 997 - 1014.e11
  04/08/2025 Authors: Madden PJ; Marina-Zrate E; Rodrigues KA; Steichen JM; Shil M; Ni K; Michaels KK; Maiorino L; Upadhyay AA; Saha S
• Safety, pharmacokinetics, and biological activity of CD4-mimetic BNM-III-170 in SHIV-infected rhesus macaques.
  J Virol Page(s): e0006225
  04/07/2025 Authors: Viox EG; Richard J; Grandea AG; Nguyen K; Harper J; Auger J; Ding S; Gasser R; Prvost J; Marchitto L
• TGF- mediates epigenetic control of innate antiviral responses and SIV reservoir size.
  Res Sq
  03/19/2025 Authors: Ghneim K; Ten-Caten F; Santana AC; Latif MB; Dinamarca DAD; Garca-Salum T; Estrada PMDR; Sohal P; Strongin Z; Harper J
• Author Correction: Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption.
  Nat Immunol Volume: 26 Page(s): 524
  03/01/2025 Authors: Pereira Ribeiro S; Strongin Z; Soudeyns H; Ten-Caten F; Ghneim K; Pacheco Sanchez G; Xavier de Medeiros G; Del Rio Estrada PM; Pelletier A-N; Hoang T
• Immune-mediated strategies to solving the HIV reservoir problem.
  Nat Rev Immunol
  02/13/2025 Authors: Kulpa DA; Paiardini M; Silvestri G
• SIV infection induces alterations in gene expression and loss of interneurons in Rhesus Macaque frontal cortex during early systemic infection.
  Transl Psychiatry Volume: 15 Page(s): 38
  01/31/2025 Authors: Crist RC; Chehimi SN; Divakaran SS; Montague MJ; Tremblay S; Snyder-Mackler N; Bohlen MO; Chiou KL; Zintel TM; Cayo Biobank Research Unit
• Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques.
  bioRxiv
  11/29/2024 Authors: Pratap PP; Cottrell CA; Quinn J; Carnathan DG; Bader DLV; Tran AS; Enemuo CA; Ngo JT; Richey ST; Gao H
• SIV infection in sooty mangabeys does not impact survival but changes the relative frequency of the main cause of death.
  mBio Volume: 15 Page(s): e0163924
  10/16/2024 Authors: Ceriani C; Beisner B; Crane M; Cohen J; Moore IN; Kulpa DA; Hahn BH; Silvestri G
• Dual blockade of IL-10 and PD-1 leads to control of SIV viral rebound following analytical treatment interruption.
  Nat Immunol Volume: 25 Page(s): 1900 - 1912
  10/01/2024 Authors: Pereira Ribeiro S; Strongin Z; Soudeyns H; Ten-Caten F; Ghneim K; Pacheco Sanchez G; Xavier de Medeiros G; Del Rio Estrada PM; Pelletier A-N; Hoang T
• Assessing the impact of autologous virus neutralizing antibodies on viral rebound time in postnatally SHIV-infected ART-treated infant rhesus macaques.
  Epidemics Volume: 48 Page(s): 100780
  09/01/2024 Authors: Mainou E; Berendam SJ; Obregon-Perko V; Uffman EA; Phan CT; Shaw GM; Bar KJ; Kumar MR; Fray EJ; Siliciano JM
• Priming antibody responses to the fusion peptide in rhesus macaques.
  NPJ Vaccines Volume: 9 Page(s): 126
  07/12/2024 Authors: Cottrell CA; Pratap PP; Cirelli KM; Carnathan DG; Enemuo CA; Antanasijevic A; Ozorowski G; Sewall LM; Gao H; Allen JD
• Distinct SIV-specific CD8+ T cells in the lymph node exhibit simultaneous effector and stem-like profiles and are associated with limited SIV persistence.
  Nat Immunol Volume: 25 Page(s): 1245 - 1256
  07/01/2024 Authors: Strongin Z; Raymond Marchand L; Deleage C; Pampena MB; Cardenas MA; Beusch CM; Hoang TN; Urban EA; Gourves M; Nguyen K
• Author Correction: Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
  Nat Immunol Volume: 25 Page(s): 1307
  07/01/2024 Authors: Schiffner T; Phung I; Ray R; Irimia A; Tian M; Swanson O; Lee JH; Lee C-CD; Marina-Zrate E; Cho SY
• Assessing the impact of autologous neutralizing antibodies on rebound dynamics in postnatally SHIV-infected ART-treated infant rhesus macaques.
  bioRxiv
  06/03/2024 Authors: Mainou E; Berendam SJ; Obregon-Perko V; Uffman EA; Phan CT; Shaw GM; Bar KJ; Kumar MR; Fray EJ; Siliciano JM
• Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
  Nat Immunol Volume: 25 Page(s): 1073 - 1082
  06/01/2024 Authors: Schiffner T; Phung I; Ray R; Irimia A; Tian M; Swanson O; Lee JH; Lee C-CD; Marina-Zrate E; Cho SY
• Comparative analysis of within-host dynamics of acute infection and viral rebound dynamics in postnatally SHIV-infected ART-treated infant rhesus macaques.
  bioRxiv
  05/23/2024 Authors: Mainou E; Berendam SJ; Obregon-Perko V; Uffman EA; Phan CT; Shaw GM; Bar KJ; Kumar MR; Fray EJ; Siliciano JM
• B cell immunofocusing and repriming in two HIV-1 Env immunization regimens.
  Res Sq
  04/08/2024 Authors: DeLuca JM; Blasi M; Jha S; Shen X; Pollara J; Kerkau M; Purwar M; Carnathan DG; Negri D; Cara A
• Efficacy of Alum-Adjuvanted Peptide and Carbohydrate Conjugate Vaccine Candidates against Group A Streptococcus Pharyngeal Infection in a Non-Human Primate Model.
  Vaccines (Basel) Volume: 12
  04/04/2024 Authors: Rivera-Hernandez T; Carnathan DG; Richter J; Marchant P; Cork AJ; Elangovan G; Henningham A; Cole JN; Choudhury B; Moyle PM
• The CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression.
  Cell Volume: 187 Page(s): 1223 - 1237.e16
  02/29/2024 Authors: Wang Q; Clark KM; Tiwari R; Raju N; Tharp GK; Rogers J; Harris RA; Raveendran M; Bosinger SE; Burdo TH
• A novel HIV triple broadly neutralizing antibody (bNAb) combination-based passive immunization of infant rhesus macaques achieves durable protective plasma neutralization levels and mediates anti-viral effector functions.
  PLoS One Volume: 19 Page(s): e0312411
  01/01/2024 Authors: Dankwa S; Kosman C; Dennis M; Giorgi EE; Vuong K; Pahountis I; Garza A; Binuya C; McCarthy J; Mayer BT
• Vpr attenuates antiviral immune responses and is critical for full pathogenicity of SIVmac239 in rhesus macaques.
  iScience Volume: 26 Page(s): 108351
  12/15/2023 Authors: Lalibert A; Prelli Bozzo C; Stahl-Hennig C; Hunszinger V; Joas S; Sauermann U; Roshani B; Klippert A; Daskalaki M; Mtz-Rensing K
• Transient CD4+ T cell depletion during suppressive ART reduces the HIV reservoir in humanized mice.
  PLoS Pathog Volume: 19 Page(s): e1011824
  12/01/2023 Authors: Ling L; De C; Spagnuolo RA; Begum N; Falcinelli SD; Archin NM; Kovarova M; Silvestri G; Wahl A; Margolis DM
• A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates.
  Nat Commun Volume: 14 Page(s): 7107
  11/04/2023 Authors: Phung I; Rodrigues KA; Marina-Zrate E; Maiorino L; Pahar B; Lee W-H; Melo M; Kaur A; Allers C; Fahlberg M
• AZD5582 plus SIV-specific antibodies reduce lymph node viral reservoirs in antiretroviral therapy-suppressed macaques.
  Nat Med Volume: 29 Page(s): 2535 - 2546
  10/01/2023 Authors: Dashti A; Sukkestad S; Horner AM; Neja M; Siddiqi Z; Waller C; Goldy J; Monroe D; Lin A; Schoof N
• Impact of the IL-15 superagonist N-803 on latency reversal induced by AZD5582 and on immune cells in ART-suppressed rhesus macaques
  Volume: 52 Page(s): 308 - 309
  10/01/2023 Authors: Dashti A; Sukkestad S; Horner AM; Neja M; Lin A; Schoof N; Singh V; Mavigner M; King H; Mason RD
• Assessing the impact of autologous neutralizing antibodies on viral rebound in postnatally SHIV-infected ART-treated infant rhesus macaques.
  bioRxiv
  09/14/2023 Authors: Mainou E; Berendam SJ; Obregon-Perko V; Uffman EA; Phan CT; Shaw GM; Bar KJ; Kumar MR; Fray EJ; Siliciano JM
• Anti-SIV Env RhmAbs +/-CD8a depletion and N-803 in ART-suppressed rhesus macaques leads to post-treatment control of viremia in a subset of animals
  Volume: 26
  08/01/2023 Authors: Singh V; Burgess D; Dashti A; McBrien J; King H; Mason R; Safrit J; Lifson J; Tuyishime M; Ferrari G
• Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.
  Sci Immunol Volume: 8 Page(s): eadg0033
  07/28/2023 Authors: Viox EG; Hoang TN; Upadhyay AA; Nchioua R; Hirschenberger M; Strongin Z; Tharp GK; Pino M; Nguyen K; Harper JL
• Lymph-Node-Based CD3+ CD20+ Cells Emerge from Membrane Exchange between T Follicular Helper Cells and B Cells and Increase Their Frequency following Simian Immunodeficiency Virus Infection.
  J Virol Volume: 97 Page(s): e0176022
  06/29/2023 Authors: Samer S; Chowdhury A; Wiche Salinas TR; Estrada PMDR; Reuter M; Tharp G; Bosinger S; Cervasi B; Auger J; Gill K
• Focusing antibody responses to the fusion peptide in rhesus macaques.
  bioRxiv
  06/27/2023 Authors: Cottrell CA; Pratap PP; Cirelli KM; Carnathan DG; Enemuo CA; Antanasijevic A; Ozorowski G; Sewall LM; Gao H; Greene KM
• Immune resilience despite inflammatory stress promotes longevity and favorable health outcomes including resistance to infection.
  Nat Commun Volume: 14 Page(s): 3286
  06/13/2023 Authors: Ahuja SK; Manoharan MS; Lee GC; McKinnon LR; Meunier JA; Steri M; Harper N; Fiorillo E; Smith AM; Restrepo MI
• Human T cells efficiently control RSV infection.
  JCI Insight Volume: 8
  06/08/2023 Authors: De C; Pickles RJ; Yao W; Liao B; Boone A; Choi M; Battaglia DM; Askin FB; Whitmire JK; Silvestri G
• CD8+ Tcells promote HIV latency by remodeling CD4+ Tcell metabolism to enhance their survival, quiescence, and stemness.
  Immunity Volume: 56 Page(s): 1132 - 1147.e6
  05/09/2023 Authors: Mutascio S; Mota T; Franchitti L; Sharma AA; Willemse A; Bergstresser SN; Wang H; Statzu M; Tharp GK; Weiler J
• Virology under the Microscope-a Call for Rational Discourse.
  mSphere Volume: 8 Page(s): e0003423
  04/01/2023 Authors: Goodrum F; Lowen AC; Lakdawala S; Alwine J; Casadevall A; Imperiale MJ; Atwood W; Avgousti D; Baines J; Banfield B
• Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19.
  Nat Commun Volume: 14 Page(s): 1638
  04/04/2023 Authors: Druzak S; Iffrig E; Roberts BR; Zhang T; Fibben KS; Sakurai Y; Verkerke HP; Rostad CA; Chahroudi A; Schneider F
• Virology under the Microscope-a Call for Rational Discourse.
  mBio Volume: 14 Page(s): e0018823
  02/28/2023 Authors: Goodrum F; Lowen AC; Lakdawala S; Alwine J; Casadevall A; Imperiale MJ; Atwood W; Avgousti D; Baines J; Banfield B
• Virology under the Microscope-a Call for Rational Discourse.
  J Virol Volume: 97 Page(s): e0008923
  02/28/2023 Authors: Goodrum F; Lowen AC; Lakdawala S; Alwine J; Casadevall A; Imperiale MJ; Atwood W; Avgousti D; Baines J; Banfield B
• CD8+ lymphocytes do not impact SIV reservoir establishment under ART.
  Nat Microbiol Volume: 8 Page(s): 299 - 308
  02/01/2023 Authors: Statzu M; Jin W; Fray EJ; Wong AKH; Kumar MR; Ferrer E; Docken SS; Pinkevych M; McBrien JB; Fennessey CM
• Author Correction: Long-primed germinal centres with enduring affinity maturation and clonal migration.
  Nature Volume: 614 Page(s): E43
  02/01/2023 Authors: Lee JH; Sutton HJ; Cottrell CA; Phung I; Ozorowski G; Sewall LM; Nedellec R; Nakao C; Silva M; Richey ST
• Modulation of type I interferon responses potently inhibits SARS-CoV-2 replication and inflammation in rhesus macaques.
  bioRxiv
  10/24/2022 Authors: Hoang TN; Viox EG; Upadhyay AA; Strongin Z; Tharp GK; Pino M; Nchioua R; Hirschenberger M; Gagne M; Nguyen K
• CD8(+) T cell depletion does not affect viral reservoir size, but influences the rebound after ART interruption in SIV-infected rhesus macaques
  Volume: 51 Page(s): 323 - 324
  10/01/2022 Authors: Statzu M; Wong A; McBrien J; Choe Y; Enemuo C; Ngo J; Jimenez L; Wang J; Pinkevych M; Docken S
• Genetic variations in the envelope of SHIV-infected ART-treated infant macaques rebound viruses that escape neutralization by autologous antibodies
  Volume: 51 Page(s): 301 - 301
  10/01/2022 Authors: Berendam S; Uffman E; Kumar A; Obregon-Perko V; Styles T; Bar K; Shaw G; Silvestri G; Amara R; Chahroudi A
• Long-primed germinal centres with enduring affinity maturation and clonal migration.
  Nature Volume: 609 Page(s): 998 - 1004
  09/01/2022 Authors: Lee JH; Sutton HJ; Cottrell CA; Phung I; Ozorowski G; Sewall LM; Nedellec R; Nakao C; Silva M; Richey ST
• CD8 depletion and N-803 plus anti-SIV Env RhmAbs in ART-suppressed rhesus macaques
  Volume: 25 Page(s): 237 - 237
  08/01/2022 Authors: Singh V; Burgess D; Dashti A; McBrien J; King H; Mason R; Safrit J; Lifson J; Tuyishime M; Ferrari G
• AZD5582 and SIV Env-targeting rhesus monoclonal antibodies (RhmAbs) +/- N-803 in SIV-infected ART-suppressed rhesus macaques
  Volume: 25 Page(s): 7 - 7
  08/01/2022 Authors: Dashti A; Sukkestad S; Horner AM; Neja M; Lin A; Schoof N; Mavigner M; Lifson JD; Falcinelli SD; Sacha J
• The role of CD101-expressing CD4 T cells in HIV/SIV pathogenesis and persistence.
  PLoS Pathog Volume: 18 Page(s): e1010723
  07/01/2022 Authors: Strongin Z; Hoang TN; Tharp GK; Rahmberg AR; Harper JL; Nguyen K; Franchitti L; Cervasi B; Lee M; Zhang Z
• Interleukin-10 contributes to reservoir establishment and persistence in SIV-infected macaques treated with antiretroviral therapy.
  J Clin Invest Volume: 132
  04/15/2022 Authors: Harper J; Ribeiro SP; Chan CN; Aid M; Deleage C; Micci L; Pino M; Cervasi B; Raghunathan G; Rimmer E
• Limited induction of SARS-CoV-2-specific T cell responses in children with multisystem inflammatory syndrome compared with COVID-19.
  JCI Insight Volume: 7
  02/22/2022 Authors: Singh V; Obregon-Perko V; Lapp SA; Horner AM; Brooks A; Macoy L; Hussaini L; Lu A; Gibson T; Silvestri G
• From structure to sequence: Antibody discovery using cryoEM.
  Sci Adv Volume: 8 Page(s): eabk2039
  01/21/2022 Authors: Antanasijevic A; Bowman CA; Kirchdoerfer RN; Cottrell CA; Ozorowski G; Upadhyay AA; Cirelli KM; Carnathan DG; Enemuo CA; Sewall LM
• A flow-cytometry-based protocol using diverse cell types for detecting autoantibodies from human plasma and serum samples.
  STAR Protoc Volume: 2 Page(s): 100924
  12/17/2021 Authors: Wong AKH; Kulpa DA; Silvestri G; Maier CL
• Phosphate-mediated coanchoring of RBD immunogens and molecular adjuvants to alum potentiates humoral immunity against SARS-CoV-2.
  Sci Adv Volume: 7 Page(s): eabj6538
  12/10/2021 Authors: Rodrigues KA; Rodriguez-Aponte SA; Dalvie NC; Lee JH; Abraham W; Carnathan DG; Jimenez LE; Ngo JT; Chang JYH; Zhang Z
• Dynamics and origin of rebound viremia in SHIV-infected infant macaques following interruption of long-term ART.
  JCI Insight Volume: 6
  12/08/2021 Authors: Obregon-Perko V; Bricker KM; Mensah G; Uddin F; Rotolo L; Vanover D; Desai Y; Santangelo PJ; Jean S; Wood JS
• A particulate saponin/TLR agonist vaccine adjuvant alters lymph flow and modulates adaptive immunity.
  Sci Immunol Volume: 6 Page(s): eabf1152
  12/03/2021 Authors: Silva M; Kato Y; Melo MB; Phung I; Freeman BL; Li Z; Roh K; Van Wijnbergen JW; Watkins H; Enemuo CA
• Beyond vascular surgery: a general overview from the web.
  J Cardiovasc Surg (Torino) Volume: 62 Page(s): 571 - 572
  12/01/2021 Authors: Spada P; Silvestri G
• The Longest Persistence of Viable SARS-CoV-2 With Recurrence of Viremia and Relapsing Symptomatic COVID-19 in an Immunocompromised Patient-A Case Study.
  Open Forum Infect Dis Volume: 8 Page(s): ofab217
  11/01/2021 Authors: Sepulcri C; Dentone C; Mikulska M; Bruzzone B; Lai A; Fenoglio D; Bozzano F; Bergna A; Parodi A; Altosole T
• Histopathological findings and clinicopathologic correlation in COVID-19: a systematic review.
  Mod Pathol Volume: 34 Page(s): 1614 - 1633
  09/01/2021 Authors: Caramaschi S; Kapp ME; Miller SE; Eisenberg R; Johnson J; Epperly G; Maiorana A; Silvestri G; Giannico GA
• Polyclonal antibody responses to HIV Env immunogens resolved using cryoEM.
  Nat Commun Volume: 12 Page(s): 4817
  08/10/2021 Authors: Antanasijevic A; Sewall LM; Cottrell CA; Carnathan DG; Jimenez LE; Ngo JT; Silverman JB; Groschel B; Georgeson E; Bhiman J
• CD8+lymphocyte mediated suppression of HIV expression in CD4(+) T cells
  Volume: 51 Page(s): 104 - 104
  08/01/2021 Authors: Franchitti L; Sharma AA; Yoon J; White E; Zhang Z; Wang H; Statzu M; Willemse AE; Bateganya L; Silvestri G
• Combined PET and whole-tissue imaging of lymphatic-targeting vaccines in non-human primates.
  Biomaterials Volume: 275 Page(s): 120868
  08/01/2021 Authors: Martin JT; Hartwell BL; Kumarapperuma SC; Melo MB; Carnathan DG; Cossette BJ; Adams J; Gong S; Zhang W; Tokatlian T
• Broad auto-reactive IgM responses are common in critically ill patients, including those with COVID-19.
  Cell Rep Med Volume: 2 Page(s): 100321
  06/01/2021 Authors: Wong AKH; Woodhouse I; Schneider F; Kulpa DA; Silvestri G; Maier CL
• Tissue-specific transcriptional profiling of plasmacytoid dendritic cells reveals a hyperactivated state in chronic SIV infection.
  PLoS Pathog Volume: 17 Page(s): e1009674
  06/01/2021 Authors: Lee MY-H; Upadhyay AA; Walum H; Chan CN; Dawoud RA; Grech C; Harper JL; Karunakaran KA; Nelson SA; Mahar EA
• IL-21 and IFN therapy rescues terminallydifferentiated NK cells and limits SIV reservoir in ART-treated macaques.
  Nat Commun Volume: 12 Page(s): 2866
  05/17/2021 Authors: Harper J; Huot N; Micci L; Tharp G; King C; Rascle P; Shenvi N; Wang H; Galardi C; Upadhyay AA
• CD8 lymphocyte depletion enhances the latency reversal activity of the SMAC mimetic AZD5582 in ART-suppressed SIV-infected rhesus macaques.
  J Virol Volume: 95
  03/25/2021 Authors: Mavigner M; Liao LE; Brooks AD; Ke R; Mattingly C; Schoof N; McBrien J; Carnathan D; Liang S; Vanderford TH
• Unprimed CD8+lymphocytes promote the maintenance of HIV latency in CD4+T cells
  Volume: 24
  02/01/2021 Authors: Franchitti L; Zhang Z; Statzu M; Wang H; Paiardini M; Silvestri G; Kulpa D
• Baricitinib treatment resolves lower-airway macrophage inflammation and neutrophil recruitment in SARS-CoV-2-infected rhesus macaques.
  Cell Volume: 184 Page(s): 460 - 475.e21
  01/21/2021 Authors: Hoang TN; Pino M; Boddapati AK; Viox EG; Starke CE; Upadhyay AA; Gumber S; Nekorchuk M; Busman-Sahay K; Strongin Z
• Elimination of SHIV Infected Cells by Combinations of Bispecific HIVxCD3 DART Molecules.
  Front Immunol Volume: 12 Page(s): 710273
  01/01/2021 Authors: Tuyishime M; Dashti A; Faircloth K; Jha S; Nordstrom JL; Haynes BF; Silvestri G; Chahroudi A; Margolis DM; Ferrari G
• Introduction to the Special Issue: Immunology of HIV and SIV infection.
  Semin Immunol Volume: 51 Page(s): 101484
  01/01/2021 Authors: Kulpa DA; Silvestri G
• Is France Once Again Looking for a Scapegoat?
  Pathog Immun Volume: 6 Page(s): 149 - 152
  01/01/2021 Authors: Lederman MM; Flier JS; Hale P; Haase AT; Powderly W; Reiss P; Silvestri G; Sekaly RP; Paiardini M; Weissman D
• Broad Auto-Reactive IgM Responses Are Common In Critically Ill COVID-19 Patients.
  Res Sq
  12/31/2020 Authors: Maier C; Wong A; Woodhouse I; Schneider F; Kulpa D; Silvestri G
• Simian-Human Immunodeficiency Virus SHIV.C.CH505 Persistence in ART-Suppressed Infant Macaques Is Characterized by Elevated SHIV RNA in the Gut and a High Abundance of Intact SHIV DNA in Naive CD4+ T Cells.
  J Virol Volume: 95
  12/22/2020 Authors: Obregon-Perko V; Bricker KM; Mensah G; Uddin F; Kumar MR; Fray EJ; Siliciano RF; Schoof N; Horner A; Mavigner M
• Erratum for Rivera-Hernandez et al., "An Experimental Group A Streptococcus Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model".
  mBio Volume: 11
  12/01/2020 Authors: Rivera-Hernandez T; Carnathan DG; Jones S; Cork AJ; Davies MR; Moyle PM; Toth I; Batzloff MR; McCarthy J; Nizet V
• SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques.
  Volume: 94
  10/14/2020 Authors: Dashti A; Waller C; Mavigner M; Schoof N; Bar KJ; Shaw GM; Vanderford TH; Liang S; Lifson JD; Dunham RM
• Lymph node-based CD3(+)CD20(+)"double-positive" cells results from trogocytosis between follicular helper T cells and B cells and expands following SIV infection in rhesus macaques
  Volume: 49 Page(s): 263 - 263
  10/01/2020 Authors: Samer S; Chowdhury A; Estrada PDR; Reuter M; Reyes-Teran G; Bosinger S; Estes JD; Betts MR; Silvestri G; Paiardini M
• Viral & immune dynamics in an NHP model of pediatric HIV infection: studies to inform cure strategies
  Volume: 49 Page(s): 236 - 236
  10/01/2020 Authors: Obregon-Perko V; Bricker K; Uddin F; Berendam S; Fouda G; Bar K; Shaw G; Silvestri G; Permar S; Chahroudi A
• Combination of CD8 Depletion and Interleukin-15 Superagonist N-803 Induces Virus Reactivation in Simian-Human Immunodeficiency Virus-Infected, Long-Term ART-Treated Rhesus Macaques.
  J Virol Volume: 94
  09/15/2020 Authors: McBrien JB; Wong AKH; White E; Carnathan DG; Lee JH; Safrit JT; Vanderford TH; Paiardini M; Chahroudi A; Silvestri G
• Regional Brain Recovery from Acute Synaptic Injury in Simian Immunodeficiency Virus-Infected Rhesus Macaques Associates with Heme Oxygenase Isoform Expression.
  J Virol Volume: 94
  09/15/2020 Authors: Garcia-Mesa Y; Garza R; Diaz Ortiz ME; Gruenewald AL; Bastien BL; Lobrovich R; Irwin DJ; Betts MR; Silvestri G; Kolson DL
• Innate, non-cytolytic CD8+ T cell-mediated suppression of HIV replication by MHC-independent inhibition of virus transcription.
  PLoS Pathog Volume: 16 Page(s): e1008821
  09/01/2020 Authors: Zanoni M; Palesch D; Pinacchio C; Statzu M; Tharp GK; Paiardini M; Chahroudi A; Bosinger SE; Yoon J; Cox B
• Lower nasopharyngeal viral load during the latest phase of COVID-19 pandemic in a Northern Italy University Hospital.
  Clin Chem Lab Med Volume: 58 Page(s): 1573 - 1577
  08/27/2020 Authors: Clementi N; Ferrarese R; Tonelli M; Amato V; Racca S; Locatelli M; Lippi G; Silvestri G; Clementi M; Mancini N
• Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations.
  NPJ Vaccines Volume: 5 Page(s): 72
  08/05/2020 Authors: Martin JT; Cottrell CA; Antanasijevic A; Carnathan DG; Cossette BJ; Enemuo CA; Gebru EH; Choe Y; Viviano F; Fischinger S
• Mapping the immunogenic landscape of near-native HIV-1 envelope trimers in non-human primates.
  PLoS Pathog Volume: 16 Page(s): e1008753
  08/01/2020 Authors: Cottrell CA; van Schooten J; Bowman CA; Yuan M; Oyen D; Shin M; Morpurgo R; van der Woude P; van Breemen M; Torres JL
• Virologic and Immunologic Features of Simian Immunodeficiency Virus Control Post-ART Interruption in Rhesus Macaques.
  J Virol Volume: 94
  07/01/2020 Authors: Strongin Z; Micci L; Fromentin R; Harper J; McBrien J; Ryan E; Shenvi N; Easley K; Chomont N; Silvestri G
• Contribution of monocytes and CD4 T-cell subsets in maintaining viral reservoirs in SIV-infected macaques treated early after infection with antiretroviral drugs
  Volume: 23 Page(s): 7 - 8
  07/01/2020 Authors: Rabezanahary H; Clain J; Racine G; Andreani G; Benmadid-Laktout G; Zghidi-Abouzid O; Silvestri G; Estaquier J
• Alterations of redox and iron metabolism accompany the development of HIV latency.
  EMBO J Volume: 39 Page(s): e102209
  05/04/2020 Authors: Shytaj IL; Lucic B; Forcato M; Penzo C; Billingsley J; Laketa V; Bosinger S; Stanic M; Gregoretti F; Antonelli L
• CTLA-4 and PD-1 dual blockade induces SIV reactivation without control of rebound after antiretroviral therapy interruption.
  Nat Med Volume: 26 Page(s): 519 - 528
  04/01/2020 Authors: Harper J; Gordon S; Chan CN; Wang H; Lindemuth E; Galardi C; Falcinelli SD; Raines SLM; Read JL; Nguyen K
• Correction for Mavigner et al., "Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques".
  J Virol Volume: 94
  03/31/2020 Authors: Mavigner M; Habib J; Deleage C; Rosen E; Mattingly C; Bricker K; Kashuba A; Amblard F; Schinazi RF; Lawson B
• Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion.
  Cell Rep Volume: 30 Page(s): 2261 - 2274.e7
  02/18/2020 Authors: Joas S; Sauermann U; Roshani B; Klippert A; Daskalaki M; Mtz-Rensing K; Stolte-Leeb N; Heigele A; Tharp GK; Gupta PM
• Author Correction: Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells.
  Nature Volume: 578 Page(s): E21
  02/01/2020 Authors: McBrien JB; Mavigner M; Franchitti L; Smith SA; White E; Tharp GK; Walum H; Busman-Sahay K; Aguilera-Sandoval CR; Thayer WO
• Systemic HIV and SIV latency reversal via non-canonical NF-B signalling in vivo.
  Nature Volume: 578 Page(s): 160 - 165
  02/01/2020 Authors: Nixon CC; Mavigner M; Sampey GC; Brooks AD; Spagnuolo RA; Irlbeck DM; Mattingly C; Ho PT; Schoof N; Cammon CG
• Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells.
  Nature Volume: 578 Page(s): 154 - 159
  02/01/2020 Authors: McBrien JB; Mavigner M; Franchitti L; Smith SA; White E; Tharp GK; Walum H; Busman-Sahay K; Aguilera-Sandoval CR; Thayer WO
• Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance.
  Cell Volume: 180 Page(s): 206
  01/09/2020 Authors: Cirelli KM; Carnathan DG; Nogal B; Martin JT; Rodriguez OL; Upadhyay AA; Enemuo CA; Gebru EH; Choe Y; Viviano F
• Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers.
  Front Immunol Volume: 11 Page(s): 1213
  01/01/2020 Authors: Carnathan DG; Kaushik K; Ellebedy AH; Enemuo CA; Gebru EH; Dhadvai P; Rasheed MAU; Pauthner MG; Ozorowski G; Ahmed R
• Targeting HIV Env immunogens to B cell follicles in nonhuman primates through immune complex or protein nanoparticle formulations.
  NPJ Vaccines Volume: 5 Page(s): 72
  01/01/2020 Authors: Martin JT; Cottrell CA; Antanasijevic A; Carnathan DG; Cossette BJ; Enemuo CA; Gebru EH; Choe Y; Viviano F; Fischinger S
• Despite early antiretroviral therapy effector memory and follicular helper CD4 T cells are major reservoirs in visceral lymphoid tissues of SIV-infected macaques.
  Mucosal Immunol Volume: 13 Page(s): 149 - 160
  01/01/2020 Authors: Rabezanahary H; Moukambi F; Palesch D; Clain J; Racine G; Andreani G; Benmadid-Laktout G; Zghidi-Abouzid O; Soundaramourty C; Tremblay C
• Author Correction: Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control.
  Nat Commun Volume: 10 Page(s): 5768
  12/13/2019 Authors: Barrenas F; Raehtz K; Xu C; Law L; Green RR; Silvestri G; Bosinger SE; Nishida A; Li Q; Lu W
• Strong TH1-biased CD4 T cell responses are associated with diminished SIV vaccine efficacy.
  Sci Transl Med Volume: 11
  11/20/2019 Authors: Chamcha V; Reddy PBJ; Kannanganat S; Wilkins C; Gangadhara S; Velu V; Green R; Law GL; Chang J; Bowen JR
• Rapid Germinal Center and Antibody Responses in Non-human Primates after a Single Nanoparticle Vaccine Immunization.
  Cell Rep Volume: 29 Page(s): 1756 - 1766.e8
  11/12/2019 Authors: Havenar-Daughton C; Carnathan DG; Boopathy AV; Upadhyay AA; Murrell B; Reiss SM; Enemuo CA; Gebru EH; Choe Y; Dhadvai P
• Macrophage-associated wound healing contributes to African green monkey SIV pathogenesis control.
  Nat Commun Volume: 10 Page(s): 5101
  11/08/2019 Authors: Barrenas F; Raehtz K; Xu C; Law L; Green RR; Silvestri G; Bosinger SE; Nishida A; Li Q; Lu W
• An NHP model of pediatric oral HIV infection and ART treatment
  Volume: 48 Page(s): 285 - 285
  10/01/2019 Authors: Obregon-Perko V; Bricker K; Fouda G; Bar K; Shaw G; Silvestri G; Permar S; Chahroudi A
• Immunological effects of the IL-15 superagonist N-803 in SIV-infected ART-treated rhesus macaques
  Volume: 48 Page(s): 307 - 308
  10/01/2019 Authors: McBrien J; White E; Tharp G; Jeng E; Wong H; Safrit J; Paiardini M; Vanderford T; Lifson J; Bosinger S
• Fingolimod retains cytolytic T cells and limits T follicular helper cell infection in lymphoid sites of SIV persistence.
  PLoS Pathog Volume: 15 Page(s): e1008081
  10/01/2019 Authors: Pino M; Paganini S; Deleage C; Padhan K; Harper JL; King CT; Micci L; Cervasi B; Mudd JC; Gill KP
• Sting agonist as a kick and kill agent to target the HIV reservoir
  Volume: 22 Page(s): 42 - 42
  07/01/2019 Authors: Mavigner M; Brooks AD; Koblansky A; Galardi C; Madsen H; Margolis DM; Silvestri G; Chahroudi A
• CD8+lymphocyte mediated suppression of HIV expression in CD4+T cells
  Volume: 22 Page(s): 105 - 105
  07/01/2019 Authors: Franchitti L; Willemse A; Yoon J; White E; Cox B; Silvestri G; Kulpa D
• Longitudinal dynamics of follicular CD4+T cells in acute SIV infection
  Volume: 22 Page(s): 40 - 41
  07/01/2019 Authors: Kuri-Cervantes L; Deleage C; Roberts E; Nguyen S; Wu V; Gunzelman H; Carnathan D; Vanderford T; Silvestri G; Betts M
• Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance.
  Cell Volume: 177 Page(s): 1153 - 1171.e28
  05/16/2019 Authors: Cirelli KM; Carnathan DG; Nogal B; Martin JT; Rodriguez OL; Upadhyay AA; Enemuo CA; Gebru EH; Choe Y; Viviano F
• An Experimental Group A Streptococcus Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model.
  mBio Volume: 10
  04/30/2019 Authors: Rivera-Hernandez T; Carnathan DG; Jones S; Cork AJ; Davies MR; Moyle PM; Toth I; Batzloff MR; McCarthy J; Nizet V
• Regional Brain Injury in the SIV Macaque Model of HIV is Linked to the Host Antioxidant Response
  Volume: 92
  04/09/2019 Authors: Garcia-Mesa Y; Bastien B; Garza R; Gruenewald A; Betts MR; Silvestri G; Kolson D
• Correction for Mavigner et al., "Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques".
  J Virol Volume: 93
  02/01/2019 Authors: Mavigner M; Habib J; Deleage C; Rosen E; Mattingly C; Bricker K; Kashuba A; Amblard F; Schinazi RF; Lawson B
• Susceptibility to SIV Infection After Adenoviral Vaccination in a Low Dose Rhesus Macaque Challenge Model.
  Pathog Immun Volume: 4 Page(s): 1 - 20
  01/01/2019 Authors: Brody IB; Calcedo R; Connell MJ; Carnathan DG; Nason M; Lawson BO; Nega MT; Boyd S; Qin Q; Vanderford TH
• Bone Marrow-Derived CD4+ T Cells Are Depleted in Simian Immunodeficiency Virus-Infected Macaques and Contribute to the Size of the Replication-Competent Reservoir.
  J Virol Volume: 93
  01/01/2019 Authors: Hoang TN; Harper JL; Pino M; Wang H; Micci L; King CT; McGary CS; McBrien JB; Cervasi B; Silvestri G
• Antibody-Mediated CD4 Depletion Induces Homeostatic CD4+ T Cell Proliferation without Detectable Virus Reactivation in Antiretroviral Therapy-Treated Simian Immunodeficiency Virus-Infected Macaques.
  J Virol Volume: 92
  11/15/2018 Authors: Kumar NA; McBrien JB; Carnathan DG; Mavigner M; Mattingly C; White ER; Viviano F; Bosinger SE; Chahroudi A; Silvestri G
• Liver Bacterial Dysbiosis Persists During Antiretroviral Therapy of SIV plus Macaques
  Volume: 34 Page(s): 308 - 308
  10/01/2018 Authors: Fisher B; Fisher C; Wood M; Driscoll C; Hensley-McBain T; Smith E; Green R; Gale M; Silvestri G; Chahroudi A
• CD8+ lymphocyte control of SIV infection during antiretroviral therapy.
  PLoS Pathog Volume: 14 Page(s): e1007350
  10/01/2018 Authors: Cao Y; Cartwright EK; Silvestri G; Perelson AS
• Simian Immunodeficiency Virus Persistence in Cellular and Anatomic Reservoirs in Antiretroviral Therapy-Suppressed Infant Rhesus Macaques.
  J Virol Volume: 92
  09/15/2018 Authors: Mavigner M; Habib J; Deleage C; Rosen E; Mattingly C; Bricker K; Kashuba A; Amblard F; Schinazi RF; Lawson B
• Short-Term Pegylated Interferon 2a Treatment Does Not Significantly Reduce the Viral Reservoir of Simian Immunodeficiency Virus-Infected, Antiretroviral Therapy-Treated Rhesus Macaques.
  J Virol Volume: 92
  07/15/2018 Authors: Palesch D; Bosinger SE; Mavigner M; Billingsley JM; Mattingly C; Carnathan DG; Paiardini M; Chahroudi A; Vanderford TH; Silvestri G
• Identification and characterization of HIV-specific resident memory CD8+ T cells in human lymphoid tissue.
  Sci Immunol Volume: 3
  06/01/2018 Authors: Buggert M; Nguyen S; Salgado-Montes de Oca G; Bengsch B; Darko S; Ransier A; Roberts ER; Del Alcazar D; Brody IB; Vella LA
• Longing for HIV protection.
  Nat Microbiol Volume: 3 Page(s): 648 - 649
  06/01/2018 Authors: Zanoni M; Palesch D; Silvestri G
• Mechanisms of CD8+ Tcell-mediated suppression of HIV/SIV replication.
  Eur J Immunol Volume: 48 Page(s): 898 - 914
  06/01/2018 Authors: McBrien JB; Kumar NA; Silvestri G
• Intragastric Administration of Lactobacillus plantarum and 2,2'-Dithiodipyridine-Inactivated Simian Immunodeficiency Virus (SIV) Does Not Protect Indian Rhesus Macaques from Intrarectal SIV Challenge or Reduce Virus Replication after Transmission.
  J Virol Volume: 92
  05/15/2018 Authors: Carnathan DG; Mackel JJ; Sweat SL; Enemuo CA; Gebru EH; Dhadvai P; Gangadhara S; Hicks S; Vanderford TH; Amara RR
• Correlates of Protection Against SIVmac251 Infection in Rhesus Macaques Immunized With Chimpanzee-Derived Adenovirus Vectors.
  EBioMedicine Volume: 31 Page(s): 25 - 35
  05/01/2018 Authors: Tuyishime S; Haut LH; Kurupati RK; Billingsley JM; Carnathan D; Gangahara S; Styles TM; Xiang Z; Li Y; Zopfs M
• Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques.
  J Virol Volume: 92
  05/01/2018 Authors: Carnathan D; Lawson B; Yu J; Patel K; Billingsley JM; Tharp GK; Delmas OM; Dawoud R; Wilkinson P; Nicolette C
• Species-specific host factors rather than virus-intrinsic virulence determine primate lentiviral pathogenicity.
  Nat Commun Volume: 9 Page(s): 1371
  04/10/2018 Authors: Joas S; Parrish EH; Gnanadurai CW; Lump E; Strzel CM; Parrish NF; Learn GH; Sauermann U; Neumann B; Rensing KM
• Postnatal Zika virus infection is associated with persistent abnormalities in brain structure, function, and behavior in infant macaques.
  Sci Transl Med Volume: 10
  04/04/2018 Authors: Mavigner M; Raper J; Kovacs-Balint Z; Gumber S; O'Neal JT; Bhaumik SK; Zhang X; Habib J; Mattingly C; McDonald CE
• The anti-caspase inhibitor Q-VD-OPH prevents AIDS disease progression in SIV-infected rhesus macaques.
  J Clin Invest Volume: 128 Page(s): 1627 - 1640
  04/02/2018 Authors: Laforge M; Silvestre R; Rodrigues V; Garibal J; Campillo-Gimenez L; Mouhamad S; Monceaux V; Cumont M-C; Rabezanahary H; Pruvost A
• Immune-based interventions for HIV cure: lessons from NHP models
  Volume: 77 Page(s): 39 - 39
  04/01/2018 Authors: Silvestri G
• Loss of CXCR6 coreceptor usage characterizes pathogenic lentiviruses.
  PLoS Pathog Volume: 14 Page(s): e1007003
  04/01/2018 Authors: Wetzel KS; Yi Y; Yadav A; Bauer AM; Bello EA; Romero DC; Bibollet-Ruche F; Hahn BH; Paiardini M; Silvestri G
• Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART.
  PLoS Pathog Volume: 14 Page(s): e1006871
  02/01/2018 Authors: Fisher BS; Green RR; Brown RR; Wood MP; Hensley-McBain T; Fisher C; Chang J; Miller AD; Bosche WJ; Lifson JD
• Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques.
  PLoS Pathog Volume: 14 Page(s): e1006913
  02/01/2018 Authors: Klasse PJ; Ketas TJ; Cottrell CA; Ozorowski G; Debnath G; Camara D; Francomano E; Pugach P; Ringe RP; LaBranche CC
• Sooty mangabey genome sequence provides insight into AIDS resistance in a natural SIV host.
  Nature Volume: 553 Page(s): 77 - 81
  01/03/2018 Authors: Palesch D; Bosinger SE; Tharp GK; Vanderford TH; Paiardini M; Chahroudi A; Johnson ZP; Kirchhoff F; Hahn BH; Norgren RB
• CTLA-4+PD-1- Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques.
  Immunity Volume: 47 Page(s): 776 - 788.e5
  10/17/2017 Authors: McGary CS; Deleage C; Harper J; Micci L; Ribeiro SP; Paganini S; Kuri-Cervantes L; Benne C; Ryan ES; Balderas R
• Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques.
  Sci Transl Med Volume: 9
  10/04/2017 Authors: Magnani DM; Rogers TF; Beutler N; Ricciardi MJ; Bailey VK; Gonzalez-Nieto L; Briney B; Sok D; Le K; Strubel A
• Liver associated inflammation and macrophage infiltration during SIV infection is partly reversed during cART
  Volume: 46 Page(s): 163 - 163
  08/01/2017 Authors: Fisher B; Brown R; Silvestri G; Chahroudi A; Klatt N; Sodora D
• FTY720 administration during ART-treatment targets cytolytic CD8+T cells to lymphoid sites of HIV persistence
  Volume: 46 Page(s): 167 - 167
  08/01/2017 Authors: Paganini S; Micci L; Harper J; Padhan K; Jean S; Silvestri G; Petrovas C; Lederman M; Paiardini M
• Direct probing of germinal center responses reveals immunological correlates for nAb responses to an engineered HIV trimer
  Volume: 46 Page(s): 174 - 174
  08/01/2017 Authors: Havenar-Daughton C; Carnathan D; de la Pena AT; Pauthner M; Briney B; Reiss S; Wood J; Kaushik K; Rosales S; Locci M
• The loss of CCR6+ and CD161+ CD4+ T-cell homeostasis contributes to disease progression in SIV-infected rhesus macaques.
  Mucosal Immunol Volume: 10 Page(s): 1082 - 1096
  07/01/2017 Authors: McGary CS; Alvarez X; Harrington S; Cervasi B; Ryan ES; Iriele RI; Paganini S; Harper JL; Easley K; Silvestri G
• Germinal centres monitored by lymph node fine-needle aspirates correlate with and predict HIV Tier 2 neutralizing antibody responses after HIV trimer immunization
  Volume: 20 Page(s): 4 - 4
  07/01/2017 Authors: Havenar-Daughton C; Carnathan D; Pauthner M; Liu J; Nkolola J; de la Pena AT; Briney B; Reiss S; Wood J; Kaushik K
• Optimized Env trimer immunization parameters amplify onset, magnitude and consistency of autologous Tier 2 neutralizing antibody development in nonhuman primates
  Volume: 20 Page(s): 3 - 4
  07/01/2017 Authors: Pauthner M; Havenar-Daughton C; Sok D; Nkolola J; Bastidas R; Boopathy A; Carnathan D; Chandrashekar A; Cirelli K; Cottrell C
• Inhibiting memory CD4+T cell self-renewal to reduce HIV persistence
  Volume: 20 Page(s): 51 - 51
  07/01/2017 Authors: Mavigner M; Zanoni M; Habib J; Mattingly C; Demarest J; Kouji H; Lawson B; Vanderford T; Tharp G; Bosinger S
• Elicitation of Robust Tier 2 Neutralizing Antibody Responses in Nonhuman Primates by HIV Envelope Trimer Immunization Using Optimized Approaches.
  Immunity Volume: 46 Page(s): 1073 - 1088.e6
  06/20/2017 Authors: Pauthner M; Havenar-Daughton C; Sok D; Nkolola JP; Bastidas R; Boopathy AV; Carnathan DG; Chandrashekar A; Cirelli KM; Cottrell CA
• New Connections: Cell-to-Cell HIV-1 Transmission, Resistance to Broadly Neutralizing Antibodies, and an Envelope Sorting Motif.
  J Virol Volume: 91
  05/01/2017 Authors: Smith SA; Derdeyn CA
• In Vivo Models of Human Immunodeficiency Virus Persistence and Cure Strategies.
  J Infect Dis Volume: 215 Page(s): S142 - S151
  03/15/2017 Authors: Nixon CC; Mavigner M; Silvestri G; Garcia JV
• Comparative analysis of activation induced marker (AIM) assays for sensitive identification of antigen-specific CD4 T cells.
  PLoS One Volume: 12 Page(s): e0186998
  01/01/2017 Authors: Reiss S; Baxter AE; Cirelli KM; Dan JM; Morou A; Daigneault A; Brassard N; Silvestri G; Routy J-P; Havenar-Daughton C
• Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques.
  PLoS Pathog Volume: 12 Page(s): e1006135
  12/01/2016 Authors: Roberts ER; Carnathan DG; Li H; Shaw GM; Silvestri G; Betts MR
• Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer.
  Cell Rep Volume: 17 Page(s): 2195 - 2209
  11/22/2016 Authors: Havenar-Daughton C; Carnathan DG; Torrents de la Pea A; Pauthner M; Briney B; Reiss SM; Wood JS; Kaushik K; van Gils MJ; Rosales SL
• Quantifying integrated SIV-DNA by repetitive-sampling Alu-gag PCR.
  J Virus Erad Volume: 2 Page(s): 219 - 226
  10/05/2016 Authors: Mavigner M; Lee ST; Habib J; Robinson C; Silvestri G; O'Doherty U; Chahroudi A
• Response to Comment on "A Cytokine-Independent Approach To Identify Antigen-Specific Human Germinal Center T Follicular Helper Cells and Rare Antigen-Specific CD4+ T Cells in Blood".
  J Immunol Volume: 197 Page(s): 2558
  10/01/2016 Authors: Dan JM; Havenar-Daughton C; Silvestri G; Sette A; Crotty S
• What pediatric nonprogressors and natural SIV hosts teach us about HIV.
  Sci Transl Med Volume: 8 Page(s): 358fs16
  09/28/2016 Authors: Chahroudi A; Silvestri G
• Efficient replication of a vpu containing SIVagm construct in African Green Monkeys requires an HIV-1 nef gene
  Volume: 13
  09/26/2016 Authors: Joas S; Parrish E; Gnanadurai CW; Lump E; Struezel CM; Parrish NF; Sauermann U; Toepfer K; Schultheiss T; Bosinger S
• CD8(+) Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy.
  Immunity Volume: 45 Page(s): 656 - 668
  09/20/2016 Authors: Cartwright EK; Spicer L; Smith SA; Lee D; Fast R; Paganini S; Lawson BO; Nega M; Easley K; Schmitz JE
• Antiretroviral Therapy in Simian Immunodeficiency Virus-Infected Sooty Mangabeys: Implications for AIDS Pathogenesis.
  J Virol Volume: 90 Page(s): 7541 - 7551
  08/15/2016 Authors: Calascibetta F; Micci L; Carnathan D; Lawson B; Vanderford TH; Bosinger SE; Easley K; Chahroudi A; Mackel J; Keele BF
• Initiation of Antiretroviral Therapy Restores CD4+ T Memory Stem Cell Homeostasis in Simian Immunodeficiency Virus-Infected Macaques.
  J Virol Volume: 90 Page(s): 6699 - 6708
  08/01/2016 Authors: Cartwright EK; Palesch D; Mavigner M; Paiardini M; Chahroudi A; Silvestri G
• International AIDS Society global scientific strategy: towards an HIV cure 2016.
  Nat Med Volume: 22 Page(s): 839 - 850
  08/01/2016 Authors: Deeks SG; Lewin SR; Ross AL; Ananworanich J; Benkirane M; Cannon P; Chomont N; Douek D; Lifson JD; Lo Y-R
• Cytokine-Independent Detection of Antigen-Specific Germinal Center T Follicular Helper Cells in Immunized Nonhuman Primates Using a Live Cell Activation-Induced Marker Technique.
  J Immunol Volume: 197 Page(s): 994 - 1002
  08/01/2016 Authors: Havenar-Daughton C; Reiss SM; Carnathan DG; Wu JE; Kendric K; Torrents de la Pea A; Kasturi SP; Dan JM; Bothwell M; Sanders RW
• Animal models to achieve an HIV cure.
  Curr Opin HIV AIDS Volume: 11 Page(s): 432 - 441
  07/01/2016 Authors: Kumar N; Chahroudi A; Silvestri G
• The Effect of Chloroquine on Immune Activation and Interferon Signatures Associated with HIV-1.
  AIDS Res Hum Retroviruses Volume: 32 Page(s): 636 - 647
  07/01/2016 Authors: Jacobson JM; Bosinger SE; Kang M; Belaunzaran-Zamudio P; Matining RM; Wilson CC; Flexner C; Clagett B; Plants J; Read S
• Neutralizing antibody affords comparable protection against vaginal and rectal simian/human immunodeficiency virus challenge in macaques.
  AIDS Volume: 30 Page(s): 1543 - 1551
  06/19/2016 Authors: Moldt B; Le KM; Carnathan DG; Whitney JB; Schultz N; Lewis MG; Borducchi EN; Smith KM; Mackel JJ; Sweat SL
• Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full-Length M Protein in Cutaneous and Invasive Disease Models.
  mBio Volume: 7
  06/14/2016 Authors: Rivera-Hernandez T; Pandey M; Henningham A; Cole J; Choudhury B; Cork AJ; Gillen CM; Ghaffar KA; West NP; Silvestri G
• Immune activation in HIV infection: what can the natural hosts of simian immunodeficiency virus teach us?
  Curr Opin HIV AIDS Volume: 11 Page(s): 201 - 208
  03/01/2016 Authors: Ploquin MJ; Silvestri G; Mller-Trutwin M
• HIV and Tfh Cells: Circulating New Ideas to Identify and Protect.
  Immunity Volume: 44 Page(s): 16 - 18
  01/19/2016 Authors: Chahroudi A; Silvestri G
• CD19xCD3 DART protein mediates human B-cell depletion in vivo in humanized BLT mice.
  Mol Ther Oncolytics Volume: 3 Page(s): 15024
  01/01/2016 Authors: Tsai P; Thayer WO; Liu L; Silvestri G; Nordstrom JL; Garcia JV
• Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys.
  PLoS One Volume: 11 Page(s): e0156352
  01/01/2016 Authors: Ortiz AM; Carnathan DG; Yu J; Sheehan KM; Kim P; Reynaldi A; Vanderford TH; Klatt NR; Brenchley JM; Davenport MP
• Coexpression Network Analysis of Benign and Malignant Phenotypes of SIV-Infected Sooty Mangabey and Rhesus Macaque.
  PLoS One Volume: 11 Page(s): e0156170
  01/01/2016 Authors: Yang Z-W; Jiang Y-H; Ma C; Silvestri G; Bosinger SE; Li B-L; Jong A; Zhou Y-H; Huang S-H
• Correction: Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (T(FH)) in Simian Immunodeficiency Virus-Infected Rhesus Macaques May Contribute to Accumulation of T(FH) in Chronic Infection.
  J Immunol Volume: 195 Page(s): 5843
  12/15/2015 Authors: Chowdhury A; Del Rio Estrada PM; Tharp GK; Trible RP; Amara RR; Chahroudi A; Reyes-Teran G; Bosinger SE; Silvestri G
• Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques.
  J Clin Invest Volume: 125 Page(s): 4497 - 4513
  12/01/2015 Authors: Micci L; Ryan ES; Fromentin R; Bosinger SE; Harper JL; He T; Paganini S; Easley KA; Chahroudi A; Benne C
• Social Stress Impacts the Pathogenesis of SIV Infection and Treatment Response
  Volume: 40 Page(s): S154 - S154
  12/01/2015 Authors: Neigh G; Ethun K; Cartwright E; McGary C; Micci L; Paiardini M; Silvestri G; Chahroudi A
• Reduced Simian Immunodeficiency Virus Replication in Macrophages of Sooty Mangabeys Is Associated with Increased Expression of Host Restriction Factors.
  J Virol Volume: 89 Page(s): 10136 - 10144
  10/01/2015 Authors: Mir KD; Mavigner M; Wang C; Paiardini M; Sodora DL; Chahroudi AM; Bosinger SE; Silvestri G
• Decreased T Follicular Regulatory Cell/T Follicular Helper Cell (TFH) in Simian Immunodeficiency Virus-Infected Rhesus Macaques May Contribute to Accumulation of TFH in Chronic Infection.
  J Immunol Volume: 195 Page(s): 3237 - 3247
  10/01/2015 Authors: Chowdhury A; Del Rio Estrada PM; Tharp GK; Trible RP; Amara RR; Chahroudi A; Reyes-Teran G; Bosinger SE; Silvestri G
• INTERLEUKIN-21 REDUCES RESIDUAL INFLAMMATION AND VIRUS PERSISTENCE IN ART-TREATED SIV-INFECTED RHESUS MACAQUES
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 44 Page(s): 306 - 307
  10/01/2015 Authors: Micci L; Ryan E; McGary C; Paganini S; Silvestri G; Lifson J; Villinger F; Brenchley J; Paiardini M
• AN "HIV-1"-LIKE SIVAGM CONSTRUCT REPLICATES EFFICIENTLY IN AFRICAN GREEN MONKEYS WITHOUT CAUSING RAPID DISEASE PROGRESSION
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 44 Page(s): 317 - 317
  10/01/2015 Authors: Parrish E; Gnanadurai CW; Parrish N; Sauermann U; Toepfer K; Schultheiss T; Bosinger S; Silvestri G; Hahn B; Stahl-Hennig C
• Editorial overview: Host pathogens: New paradigms and tools to decipher and deconstruct the host-pathogen interaction.
  Curr Opin Immunol Volume: 36 Page(s): v - viii
  10/01/2015 Authors: Silvestri G; Barry PA
• ANTI-APOPTOSIS AGENT PRESERVES CD4 T CELLS AND PREVENTS DISEASE PROGRESSION IN SIV-INFECTED RHESUS MACAQUES
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 44 Page(s): 316 - 316
  10/01/2015 Authors: Laforge M; Silvestre R; Rodrigues V; Silvestri G; Senik A; Estaquier J
• EXPANDING THE NON-HUMAN PRIMATE REFERENCE TRANSCRIPTOME RESOURCE (NHPRTR): TISSUE-SPECIFIC AND IMMUNE CELL-SPECIFIC TRANSCRIPTOMES
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 44 Page(s): 346 - 346
  10/01/2015 Authors: Peng X; Xiong H; Pipes L; Kelly S; Thomas M; Law L; Luo S; Langevin S; Bosinger S; Silvestri G
• Differential Impact of In Vivo CD8+ T Lymphocyte Depletion in Controller versus Progressor Simian Immunodeficiency Virus-Infected Macaques.
  J Virol Volume: 89 Page(s): 8677 - 8686
  09/01/2015 Authors: Chowdhury A; Hayes TL; Bosinger SE; Lawson BO; Vanderford T; Schmitz JE; Paiardini M; Betts M; Chahroudi A; Estes JD
• Dualtropic CXCR6/CCR5 Simian Immunodeficiency Virus (SIV) Infection of Sooty Mangabey Primary Lymphocytes: Distinct Coreceptor Use in Natural versus Pathogenic Hosts of SIV.
  J Virol Volume: 89 Page(s): 9252 - 9261
  09/01/2015 Authors: Elliott STC; Wetzel KS; Francella N; Bryan S; Romero DC; Riddick NE; Shaheen F; Vanderford T; Derdeyn CA; Silvestri G
• Breakthrough of SIV strain smE660 challenge in SIV strain mac239-vaccinated rhesus macaques despite potent autologous neutralizing antibody responses.
  Proc Natl Acad Sci U S A Volume: 112 Page(s): 10780 - 10785
  08/25/2015 Authors: Burton SL; Kilgore KM; Smith SA; Reddy S; Hunter E; Robinson HL; Silvestri G; Amara RR; Derdeyn CA
• HIV therapeutic vaccines: moving towards a functional cure.
  Curr Opin Immunol Volume: 35 Page(s): 1 - 8
  08/01/2015 Authors: Mylvaganam GH; Silvestri G; Amara RR
• Characterization and Implementation of a Diverse Simian Immunodeficiency Virus SIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope.
  J Virol Volume: 89 Page(s): 8130 - 8151
  08/01/2015 Authors: Kilgore KM; Murphy MK; Burton SL; Wetzel KS; Smith SA; Xiao P; Reddy S; Francella N; Sodora DL; Silvestri G
• Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection.
  J Virol Volume: 89 Page(s): 6918 - 6927
  07/01/2015 Authors: Jochems SP; Jacquelin B; Chauveau L; Huot N; Petitjean G; Lepelley A; Liovat A-S; Ploquin MJ; Cartwright EK; Bosinger SE
• Second European Round Table on the Future Management of HIV: 10-11 October 2014, Barcelona, Spain.
  J Virus Erad Volume: 1 Page(s): 211 - 220
  07/01/2015 Authors: Rokx C; Richman DD; Mller-Trutwin M; Silvestri G; Lunzen J; Khoo S; Lichterfeld M; Altfeld M; Perno CF; Hunt PW
• Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas.
  mBio Volume: 6
  04/21/2015 Authors: Barbian HJ; Decker JM; Bibollet-Ruche F; Galimidi RP; West AP; Learn GH; Parrish NF; Iyer SS; Li Y; Pace CS
• Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression.
  Proc Natl Acad Sci U S A Volume: 112 Page(s): E1480 - E1489
  03/24/2015 Authors: Claiborne DT; Prince JL; Scully E; Macharia G; Micci L; Lawson B; Kopycinski J; Deymier MJ; Vanderford TH; Nganou-Makamdop K
• T memory stem cells and HIV: a long-term relationship.
  Curr HIV/AIDS Rep Volume: 12 Page(s): 33 - 40
  03/01/2015 Authors: Chahroudi A; Silvestri G; Lichterfeld M
• Lentiviral Nef proteins manipulate T cells in a subset-specific manner.
  J Virol Volume: 89 Page(s): 1986 - 2001
  02/01/2015 Authors: Yu H; Khalid M; Heigele A; Schmkel J; Usmani SM; van der Merwe J; Mnch J; Silvestri G; Kirchhoff F
• Activated CD4+CCR5+ T cells in the rectum predict increased SIV acquisition in SIVGag/Tat-vaccinated rhesus macaques.
  Proc Natl Acad Sci U S A Volume: 112 Page(s): 518 - 523
  01/13/2015 Authors: Carnathan DG; Wetzel KS; Yu J; Lee ST; Johnson BA; Paiardini M; Yan J; Morrow MP; Sardesai NY; Weiner DB
• Glucocorticoid treatment at moderate doses of SIVmac251-infected rhesus macaques decreases the frequency of circulating CD14+CD16++ monocytes but does not alter the tissue virus reservoir.
  AIDS Res Hum Retroviruses Volume: 31 Page(s): 115 - 126
  01/01/2015 Authors: Moniuszko M; Liyanage NPM; Doster MN; Parks RW; Grubczak K; Lipinska D; McKinnon K; Brown C; Hirsch V; Vaccari M
• The contribution of non-human primate models to the development of human vaccines.
  Discov Med Volume: 18 Page(s): 313 - 322
  12/01/2014 Authors: Rivera-Hernandez T; Carnathan DG; Moyle PM; Toth I; West NP; Young PR; Silvestri G; Walker MJ
• Non-human primate models for immunological studies of HIV eradication
  Volume: 67 Page(s): 64 - 64
  11/01/2014 Authors: Silvestri G
• ELEVATED LEVELS OF ACTIVATED, TARGET CD4+T CELLS IN THE RECTAL MUCOSA INCREASE THE RISK OF SIV ACQUISITION AND CORRELATE WITH HIGHER EARLY VIRUS REPLICATION IN MACAQUES VACCINATED WITH VECTORS EXPRESSING SIV GAG AND TAT
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 398 - 399
  10/01/2014 Authors: Carnathan D; Sheehan K; Yu J; Lee T; Johnson B; Weiner D; Ertl H; Silvestri G
• ADMINISTRATION OF AAV-BASED ANTI-HIV IMMUNOADHESINS IN SHIV-INFECTED RHESUS MACAQUES
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 400 - 400
  10/01/2014 Authors: Trible R; Palesch D; Gravemann S; Buening H; Kirchhoff F; Silvestri G
• DIVERGENT CD4+T MEMORY STEM CELL DYNAMICS IN PATHOGENIC AND NONPATHOGENIC SIV INFECTIONS
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 384 - 384
  10/01/2014 Authors: Cartwright E; McGary C; Cervasi B; Lawson B; Bosinger SE; Paiardini M; Vanderford TH; Chahroudi A; Silvestri G
• TARGETING SIV RESERVOIRS THROUGH AUTOLOGOUS HEMATOPOIETIC STEM CELL TRANSPLANT IN RHESUS MACAQUES
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 380 - 380
  10/01/2014 Authors: Mavigner M; Watkins B; Lawson B; Chahroudi A; Kean L; Silvestri G
• DIVERGENT PATTERNS OF ALTERNATIVE CORECEPTOR VERSUS CCR5-MEDIATED ENTRY IN NATURAL AND NON-NATURAL HOSTS OF SIV
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 383 - 384
  10/01/2014 Authors: Elliott STC; Wetzel KS; Romero DC; Francella N; Paiardini M; Derdeyn CA; Silvestri G; Apetrei C; Collman RG
• CCR6+AND CD161+MEMORY CD4+T-CELLS ARE DIFFERENTLY REGULATED DURING PATHOGENIC SIV INFECTION OF RHESUS MACAQUES AND NONPATHOGENIC SIV INFECTION OF SOOTY MANGABEYS
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 407 - 407
  10/01/2014 Authors: McGary CS; Micci L; Ryan ES; Silvestri G; Ansari AA; Paiardini M
• HIV Replicative Capacity of Transmitted Viruses Is Associated with Early Immune Activation, Exhaustion and Establishment of the Viral Reservoir.
  AIDS Res Hum Retroviruses Volume: 30 Suppl 1 Page(s): A56 - A57
  10/01/2014 Authors: Prince JL; Claiborne DT; Macharia G; Micci L; Lawson B; Scully E; Kopycinski J; Vanderford T; Tang J; Yu T
• MECHANISMS OF SIV SUPPRESSION BY CD8+LYMPHOCYTES
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 404 - 404
  10/01/2014 Authors: Hayes T; Bosinger S; Chowdhury A; Lawson B; Cervasi B; Gill K; Paiardini M; Estes J; Silvestri G
• TROGOCYTOSIS BETWEEN TFH AND GERMINAL CENTER B CELLS DURING PRIMARY IMMUNE RESPONSE IN PRIMATES
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 395 - 395
  10/01/2014 Authors: Chowdhury A; Estrada PMDR; Reuter M; Hayes T; Bosinger SE; Paiardini M; Estes JD; Betts M; Silvestri G
• CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells.
  PLoS Pathog Volume: 10 Page(s): e1004467
  10/01/2014 Authors: Micci L; Alvarez X; Iriele RI; Ortiz AM; Ryan ES; McGary CS; Deleage C; McAtee BB; He T; Apetrei C
• EXPERIMENTAL CD4 DEPLETION PRIOR TO SIV INFECTION IN MACAQUES RESULTS IN ENCEPHALITIS, MASSIVE MACROPHAGES AND MICROGLIA INFECTION, AND RAPID TURNOVER OF INFECTED CELLS
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 380 - 380
  10/01/2014 Authors: Micci L; Iriele R; Alvarez X; Ortiz A; Midkiff C; McGary C; Davenport M; Estes J; Lackner A; Silvestri G
• COMPREHENSIVE TRANSCRIPTOME ANALYSIS OF THE T CELL COMPARTMENT IN PRIMATE HOSTS OF HIV AND SIV
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 386 - 386
  10/01/2014 Authors: Bosinger S; Ortiz A; Folkner K; Patel N; Cervasi B; Gill K; Johnson Z; Silvestri G
• ANTIRETROVIRAL RESTRICTION FACTORS ARE ELEVATED IN SOOTY MANGABEY MACROPHAGES
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 408 - 408
  10/01/2014 Authors: Mir KD; Wang C; Bosinger SE; Silvestri G
• A NOVEL SYNTHETIC GM-CSF AND IL-7 FUSION CYTOKINE (GIFT7) INDUCES SUSTAINED T CELL PROLIFERATION AND UPREGULATES IL-17 FAMILY CYTOKINES IN RHESUS MACAQUE PBMCS
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 407 - 408
  10/01/2014 Authors: McGary CS; Hsieh J; Micci L; Tharp G; Bosinger SE; Silvestri G; Galipeau J; Paiardini M
• DNA/MVA and Protein-based SIV Vaccine Regimens Delivered to Rhesus Macaques with Novel Adjuvants Fail to Elicit Neutralizing Antibodies with Breadth.
  AIDS Res Hum Retroviruses Volume: 30 Suppl 1 Page(s): A84
  10/01/2014 Authors: Murphy MK; Wetzel KS; Kilgore KM; Smith SA; Burton SL; Reddy S; Francella N; Sodora DL; Silvestri G; Cole KS
• TARGET CELL AVAILABILITY, RATHER THAN BREAST MILK SPECIFIC FACTORS, DICTATES MOTHER-TO-INFANT TRANSMISSION OF SIV
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 385 - 385
  10/01/2014 Authors: Chahroudi A; Cartwright E; Carnathan DG; Lee ST; Lawson B; Carnathan PM; Hashempoor T; Murphy MK; Meeker T; Ehnert S
• INTERFERON-ALPHA BLOCKADE DURING SIV INFECTION OF RHESUS MACAQUES REDUCES LYMPHOCYTE ACTIVATION
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 389 - 389
  10/01/2014 Authors: Vanderford TH; Steel C; Zeidan J; Yu J; Zhang Y; Ahlers J; Nicolette C; Tcherepanova I; Cameron M; Sekaly RP
• DIFFERENTIAL EXPRESSION OF MUCOSAL HOMING RECEPTORS ON PLASMACYTOID DENDRITIC CELLS AND MUCOSAL CHEMOKINES IN SOOTY MANGABEYS DURING SIMIAN IMMUNODEFICIENCY VIRUS INFECTION
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 417 - 417
  10/01/2014 Authors: Folkner K; Silvestri G; Bosinger S
• DIFFERENCES IN MICRORNA EXPRESSION BETWEEN SIMIAN IMMUNODEFICIENCY VIRUS-INFECTED AND NAIVE SOOTY MANGABEYS (CERCOCEBUS ATYS) AND RHESUS MACAQUES (MACACA MULATTA)
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 411 - 412
  10/01/2014 Authors: Bosinger SE; Patel NB; Folkner KA; Tharp GK; Silvestri G; Johnson ZP
• VACCINE-INDUCED PROTECTION AGAINST SIMIAN IMMUNODEFICIENCY VIRUS
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 396 - 396
  10/01/2014 Authors: Tuyishime S; Kurupati RK; Bosinger S; Carnathan D; Haut LA; Liu Q; Silvestri G; Ertl HCJ
• Immune activation alters cellular and humoral responses to yellow fever 17D vaccine (vol 124, pg 3147, 2014)
  JOURNAL OF CLINICAL INVESTIGATION Volume: 124 Page(s): 4669 - 4669
  10/01/2014 Authors: Muyanja E; Ssemaganda A; Ngauv P; Cubas R; Perrin H; Srinivasan D; Canderan G; Lawson B; Kopycinski J; Graham AS
• Taming HIV-related inflammation with physical activity: a matter of timing.
  AIDS Res Hum Retroviruses Volume: 30 Page(s): 936 - 944
  10/01/2014 Authors: d'Ettorre G; Ceccarelli G; Giustini N; Mastroianni CM; Silvestri G; Vullo V
• LOW SOCIAL RANK PRIOR TO SIV OR SHIV INFECTION ASSOCIATES WITH HIGHER VIRAL LOAD IN CHRONIC INFECTION OF INDIVIDUALLY HOUSED RHESUS MACAQUES
  Volume: 76 Page(s): 69 - 69
  09/01/2014 Authors: Neigh GN; Hayes T; Trible R; Vanderford TH; Carnathan DG; Easley K; Paiardini M; Silvestri G
• Animal models for viral infection and cell exhaustion.
  Curr Opin HIV AIDS Volume: 9 Page(s): 492 - 499
  09/01/2014 Authors: McGary CS; Silvestri G; Paiardini M
• Persistence of virus reservoirs in ART-treated SHIV-infected rhesus macaques after autologous hematopoietic stem cell transplant.
  PLoS Pathog Volume: 10 Page(s): e1004406
  09/01/2014 Authors: Mavigner M; Watkins B; Lawson B; Lee ST; Chahroudi A; Kean L; Silvestri G
• TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.
  Dev Cell Volume: 30 Page(s): 394 - 409
  08/25/2014 Authors: Mandell MA; Jain A; Arko-Mensah J; Chauhan S; Kimura T; Dinkins C; Silvestri G; Mnch J; Kirchhoff F; Simonsen A
• Limited HIV infection of central memory and stem cell memory CD4+ T cells is associated with lack of progression in viremic individuals.
  PLoS Pathog Volume: 10 Page(s): e1004345
  08/01/2014 Authors: Klatt NR; Bosinger SE; Peck M; Richert-Spuhler LE; Heigele A; Gile JP; Patel N; Taaffe J; Julg B; Camerini D
• Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression.
  Nature Volume: 511 Page(s): 601 - 605
  07/31/2014 Authors: Sandler NG; Bosinger SE; Estes JD; Zhu RTR; Tharp GK; Boritz E; Levin D; Wijeyesinghe S; Makamdop KN; del Prete GQ
• Immune activation alters cellular and humoral responses to yellow fever 17D vaccine.
  J Clin Invest Volume: 124 Page(s): 3147 - 3158
  07/01/2014 Authors: Muyanja E; Ssemaganda A; Ngauv P; Cubas R; Perrin H; Srinivasan D; Canderan G; Lawson B; Kopycinski J; Graham AS
• Divergent CD4+ T memory stem cell dynamics in pathogenic and nonpathogenic simian immunodeficiency virus infections.
  J Immunol Volume: 192 Page(s): 4666 - 4673
  05/15/2014 Authors: Cartwright EK; McGary CS; Cervasi B; Micci L; Lawson B; Elliott STC; Collman RG; Bosinger SE; Paiardini M; Vanderford TH
• Increased stability and limited proliferation of CD4+ central memory T cells differentiate nonprogressive simian immunodeficiency virus (SIV) infection of sooty mangabeys from progressive SIV infection of rhesus macaques.
  J Virol Volume: 88 Page(s): 4533 - 4542
  04/01/2014 Authors: McGary CS; Cervasi B; Chahroudi A; Micci L; Taaffe J; Meeker T; Silvestri G; Davenport MP; Paiardini M
• Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques.
  PLoS Pathog Volume: 10 Page(s): e1003958
  03/01/2014 Authors: Chahroudi A; Cartwright E; Lee ST; Mavigner M; Carnathan DG; Lawson B; Carnathan PM; Hashempoor T; Murphy MK; Meeker T
• Reconstitution of intestinal CD4 and Th17 T cells in antiretroviral therapy suppressed HIV-infected subjects: implication for residual immune activation from the results of a clinical trial.
  PLoS One Volume: 9 Page(s): e109791
  01/01/2014 Authors: d'Ettorre G; Baroncelli S; Micci L; Ceccarelli G; Andreotti M; Sharma P; Fanello G; Fiocca F; Cavallari EN; Giustini N
• Link between primate lentiviral coreceptor usage and Nef function.
  Cell Rep Volume: 5 Page(s): 997 - 1009
  11/27/2013 Authors: Schmkel J; Li H; Shabir A; Yu H; Geyer M; Silvestri G; Sodora DL; Hahn BH; Kirchhoff F
• Decreased plasticity of coreceptor use by CD4-independent SIV Envs that emerge in vivo.
  Retrovirology Volume: 10 Page(s): 133
  11/12/2013 Authors: Francella N; Elliott STC; Yi Y; Gwyn SE; Ortiz AM; Li B; Silvestri G; Paiardini M; Derdeyn CA; Collman RG
• Limited HIV Infection of Central Memory CD4+T Cells Is Associated with Lack of Progression in Viremic Individuals
  Volume: 29 Page(s): A128 - A128
  11/01/2013 Authors: Klatt N; Bosinger S; Heigele A; Lederman M; Juelg B; Camerini D; Torti C; Martin J; Deeks S; Sinclari E
• Vif proteins from diverse primate lentiviral lineages use the same binding site in APOBEC3G.
  J Virol Volume: 87 Page(s): 11861 - 11871
  11/01/2013 Authors: Letko M; Silvestri G; Hahn BH; Bibollet-Ruche F; Gokcumen O; Simon V; Ooms M
• Estimating the contribution of the gut to plasma viral load in early SIV infection.
  Retrovirology Volume: 10 Page(s): 105
  10/14/2013 Authors: Petravic J; Vanderford TH; Silvestri G; Davenport M
• TRANSCRIPTOME ANALYSIS OF DOUBLE-NEGATIVE T CELLS IN SOOTY MANGABEYS DEMONSTRATES TH1-TH2-TH17 MULTI-FUNCTIONALITY
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 42 Page(s): 258 - 258
  10/01/2013 Authors: Sundaravaradan V; Saleem R; Gasper MA; Ortiz AM; Else J; Silvestri G; Aitchision JD; Sodora DL
• DIFFERENTIAL INFECTION PATTERNS OF CD4+T CELLS AND LYMPHOID TISSUE VIRAL BURDEN DISTINGUISH PROGRESSIVE AND NONPROGRESSIVE LENTIVIRAL INFECTIONS
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 42 Page(s): 258 - 258
  10/01/2013 Authors: Estes JD; Brenchley JM; Vinton C; Tabb B; Hao XP; Connick E; Pairidini M; Lifson JD; Silvestri G
• Immunological and virological analyses of rhesus macaques immunized with chimpanzee adenoviruses expressing the simian immunodeficiency virus Gag/Tat fusion protein and challenged intrarectally with repeated low doses of SIVmac.
  J Virol Volume: 87 Page(s): 9420 - 9430
  09/01/2013 Authors: Cervasi B; Carnathan DG; Sheehan KM; Micci L; Paiardini M; Kurupati R; Tuyishime S; Zhou XY; Else JG; Ratcliffe SJ
• CD4+ T cells support production of simian immunodeficiency virus Env antibodies that enforce CD4-dependent entry and shape tropism in vivo.
  J Virol Volume: 87 Page(s): 9719 - 9732
  09/01/2013 Authors: Francella N; Gwyn SE; Yi Y; Li B; Xiao P; Elliott STC; Ortiz AM; Hoxie JA; Paiardini M; Silvestri G
• Host-pathogen interaction in HIV infection.
  Curr Opin Immunol Volume: 25 Page(s): 463 - 469
  08/01/2013 Authors: Chowdhury A; Silvestri G
• Embracing the complexity of HIV immunology.
  Immunol Rev Volume: 254 Page(s): 5 - 9
  07/01/2013 Authors: Silvestri G
• Nonhuman primate models in AIDS research.
  Curr Opin HIV AIDS Volume: 8 Page(s): 255 - 261
  07/01/2013 Authors: Evans DT; Silvestri G
• Reduced inflammation and lymphoid tissue immunopathology in rhesus macaques receiving anti-tumor necrosis factor treatment during primary simian immunodeficiency virus infection.
  J Infect Dis Volume: 207 Page(s): 880 - 892
  03/15/2013 Authors: Tabb B; Morcock DR; Trubey CM; Quiones OA; Hao XP; Smedley J; Macallister R; Piatak M; Harris LD; Paiardini M
• Correlates of relative resistance against low-dose rectal simian immunodeficiency virus challenges in peripheral blood mononuclear cells of vaccinated rhesus macaques.
  J Leukoc Biol Volume: 93 Page(s): 437 - 448
  03/01/2013 Authors: Kurupati R; Tuyishime S; Kossenkov AV; Sazanovich M; Haut LH; Lasaro MO; Ratcliffe SJ; Bosinger SE; Carnathan DG; Lewis M
• Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure.
  J Virol Volume: 87 Page(s): 3538 - 3548
  03/01/2013 Authors: Vaccari M; Keele BF; Bosinger SE; Doster MN; Ma Z-M; Pollara J; Hryniewicz A; Ferrari G; Guan Y; Forthal DN
• Transcriptional profiling of experimental CD8(+) lymphocyte depletion in rhesus macaques infected with simian immunodeficiency virus SIVmac239.
  J Virol Volume: 87 Page(s): 433 - 443
  01/01/2013 Authors: Bosinger SE; Jochems SP; Folkner KA; Hayes TL; Klatt NR; Silvestri G
• Intact type I Interferon production and IRF7 function in sooty mangabeys.
  PLoS Pathog Volume: 9 Page(s): e1003597
  01/01/2013 Authors: Bosinger SE; Johnson ZP; Folkner KA; Patel N; Hashempour T; Jochems SP; Del Rio Estrada PM; Paiardini M; Lin R; Vanderford TH
• Microbial translocation in the pathogenesis of HIV infection and AIDS.
  Clin Microbiol Rev Volume: 26 Page(s): 2 - 18
  01/01/2013 Authors: Marchetti G; Tincati C; Silvestri G
• Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21.
  PLoS Pathog Volume: 9 Page(s): e1003471
  01/01/2013 Authors: Pallikkuth S; Micci L; Ende ZS; Iriele RI; Cervasi B; Lawson B; McGary CS; Rogers KA; Else JG; Silvestri G
• Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection.
  PLoS Pathog Volume: 9 Page(s): e1003441
  01/01/2013 Authors: Sundaravaradan V; Saleem R; Micci L; Gasper MA; Ortiz AM; Else J; Silvestri G; Paiardini M; Aitchison JD; Sodora DL
• Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections.
  Blood Volume: 120 Page(s): 4172 - 4181
  11/15/2012 Authors: Brenchley JM; Vinton C; Tabb B; Hao XP; Connick E; Paiardini M; Lifson JD; Silvestri G; Estes JD
• Paucity of IL-21-producing CD4(+) T cells is associated with Th17 cell depletion in SIV infection of rhesus macaques.
  Blood Volume: 120 Page(s): 3925 - 3935
  11/08/2012 Authors: Micci L; Cervasi B; Ende ZS; Iriele RI; Reyes-Aviles E; Vinton C; Else J; Silvestri G; Ansari AA; Villinger F
• Loss of mucosal CD103+ DCs and IL-17+ and IL-22+ lymphocytes is associated with mucosal damage in SIV infection.
  Mucosal Immunol Volume: 5 Page(s): 646 - 657
  11/01/2012 Authors: Klatt NR; Estes JD; Sun X; Ortiz AM; Barber JS; Harris LD; Cervasi B; Yokomizo LK; Pan L; Vinton CL
• A Blueprint for HIV Vaccine Discovery.
  Cell Host Microbe Volume: 12 Page(s): 396 - 407
  10/18/2012 Authors: Burton DR; Ahmed R; Barouch DH; Butera ST; Crotty S; Godzik A; Kaufmann DE; McElrath MJ; Nussenzweig MC; Pulendran B
• Differential SIV infection patterns of lymph node-resident CD4 T cells distinguishes progressive from nonprogressive SIV infection
  JOURNAL OF THE INTERNATIONAL AIDS SOCIETY Volume: 15 Page(s): 11 - 11
  10/01/2012 Authors: Vinton C; Brenchley J; Tabb B; Hao XP; Hirsch VM; Paiardini M; Lifson J; Silvestri G; Estes JD
• Improved intestinal immunity and cytotoxic potential of T cells in interleukin (IL)-21 treated SIV-infected rhesus macaques
  JOURNAL OF THE INTERNATIONAL AIDS SOCIETY Volume: 15 Page(s): 8 - 8
  10/01/2012 Authors: Pallikkuth S; Micci L; Ende Z; Iriele R; Cervasi B; Else J; Silvestri G; Villinger F; Pahwa S; Paiardini M
• Target cell restriction may limit mother-to-child transmission of SIV in sooty mangabeys
  JOURNAL OF THE INTERNATIONAL AIDS SOCIETY Volume: 15 Page(s): 26 - 26
  10/01/2012 Authors: Chahroudi A; Carnathan D; Carnathan P; Silvestri G
• Heterologous neutralization breadth persists despite B-lymphocyte dysfunction in chronic HIV-1 infection
  RETROVIROLOGY Volume: 9
  09/13/2012 Authors: Murphy MK; Boliar S; Tran TC; Carnathan DG; Armstrong WS; Silvestri G; Derdeyn CA
• Recombinant IL-21 induces perforin and granzyme B in total and virus specific CD8 Tcells in acute and early stages of SIV infection in rhesus macaques
  RETROVIROLOGY Volume: 9
  09/13/2012 Authors: Pallikkuth S; Micci L; Ende Z; Rogers K; Silvestry G; Villinger F; Paiardini M; Pahwa S
• Implementation of a biotechnological process for vat dyeing with woad.
  J Ind Microbiol Biotechnol Volume: 39 Page(s): 1309 - 1319
  09/01/2012 Authors: Osimani A; Aquilanti L; Baldini G; Silvestri G; Butta A; Clementi F
• Critical role of CD4 T cells in maintaining lymphoid tissue structure for immune cell homeostasis and reconstitution.
  Blood Volume: 120 Page(s): 1856 - 1867
  08/30/2012 Authors: Zeng M; Paiardini M; Engram JC; Beilman GJ; Chipman JG; Schacker TW; Silvestri G; Haase AT
• Selection of sourdough lactobacilli with antifungal activity for use as biopreservatives in bakery products.
  J Agric Food Chem Volume: 60 Page(s): 7719 - 7728
  08/08/2012 Authors: Garofalo C; Zannini E; Aquilanti L; Silvestri G; Fierro O; Picariello G; Clementi F
• B-lymphocyte dysfunction in chronic HIV-1 infection does not prevent cross-clade neutralization breadth.
  J Virol Volume: 86 Page(s): 8031 - 8040
  08/01/2012 Authors: Boliar S; Murphy MK; Tran TC; Carnathan DG; Armstrong WS; Silvestri G; Derdeyn CA
• Towards an HIV cure: a global scientific strategy.
  Nat Rev Immunol Volume: 12 Page(s): 607 - 614
  07/20/2012 Authors: International AIDS Society Scientific Working Group on HIV Cure; Deeks SG; Autran B; Berkhout B; Benkirane M; Cairns S; Chomont N; Chun T-W; Churchill M; Di Mascio M
• Simian immunodeficiency virus-induced alterations in monocyte production of tumor necrosis factor alpha contribute to reduced immune activation in sooty mangabeys.
  J Virol Volume: 86 Page(s): 7605 - 7615
  07/01/2012 Authors: Mir KD; Bosinger SE; Gasper M; Ho O; Else JG; Brenchley JM; Kelvin DJ; Silvestri G; Hu S-L; Sodora DL
• Treatment of SIV-infected sooty mangabeys with a type-I IFN agonist results in decreased virus replication without inducing hyperimmune activation.
  Blood Volume: 119 Page(s): 5750 - 5757
  06/14/2012 Authors: Vanderford TH; Slichter C; Rogers KA; Lawson BO; Obaede R; Else J; Villinger F; Bosinger SE; Silvestri G
• Animal models of functional HIV cure
  RETROVIROLOGY Volume: 9
  05/25/2012 Authors: Silvestri G
• A novel synthetic GMCSF and IL7 fusion cytokine (GIFT7) overcomes T cell exhaustion leading to central memory T cell formation and promoting peripheral T cell expansion in a PD1-low state
  Volume: 188
  05/01/2012 Authors: Hsieh J; Micci L; Silvestri G; Paiardini M; Galipeau J
• PD-1 blockade during chronic SIV infection reduces hyperimmune activation and microbial translocation in rhesus macaques.
  J Clin Invest Volume: 122 Page(s): 1712 - 1716
  05/01/2012 Authors: Dyavar Shetty R; Velu V; Titanji K; Bosinger SE; Freeman GJ; Silvestri G; Amara RR
• Antiviral Immune Responses, Chronic Immune Activation, and Pattern of Infected Cells in AIDS Pathogenesis: A Lesson from Non-Human Primate Models
  JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES Volume: 59 Page(s): 58 - 58
  04/01/2012 Authors: Silvestri G
• IRIS: the unfortunate rainbow of HIV.
  Blood Volume: 119 Page(s): 2971 - 2972
  03/29/2012 Authors: Chahroudi A; Silvestri G
• Natural SIV hosts: showing AIDS the door.
  Science Volume: 335 Page(s): 1188 - 1193
  03/09/2012 Authors: Chahroudi A; Bosinger SE; Vanderford TH; Paiardini M; Silvestri G
• CD4+ T cells and HIV: A paradoxical Pas de Deux.
  Sci Transl Med Volume: 4 Page(s): 123ps4
  02/29/2012 Authors: Klatt NR; Silvestri G
• Reply to "Control of Simian Immunodeficiency Virus SIVmnd-1 RNA Plasma Viremia after Coinfection or Superinfection with SIVmnd-1 in SIVmnd-2-Infected Mandrills and Vice Versa".
  J Virol Volume: 86 Page(s): 2387 - 2388
  02/01/2012 Authors: Souquiere S; Apetrei C; Chahroudi A; Pandrea I; Silvestri G; Roques P
• CCR5 blockade is well tolerated and induces changes in the tissue distribution of CCR5+ and CD25+ T cells in healthy, SIV-uninfected rhesus macaques.
  J Med Primatol Volume: 41 Page(s): 24 - 42
  02/01/2012 Authors: Taaffe JE; Bosinger SE; Del Prete GQ; Else JG; Ratcliffe S; Ward CD; Migone T; Paiardini M; Silvestri G
• Nonpathogenic simian immunodeficiency virus infections.
  Cold Spring Harb Perspect Med Volume: 2 Page(s): a007153
  01/01/2012 Authors: Klatt NR; Silvestri G; Hirsch V
• Dynamics of simian immunodeficiency virus SIVmac239 infection in pigtail macaques.
  J Virol Volume: 86 Page(s): 1203 - 1213
  01/01/2012 Authors: Klatt NR; Canary LA; Vanderford TH; Vinton CL; Engram JC; Dunham RM; Cronise HE; Swerczek JM; Lafont BAP; Picker LJ
• Systems biology of natural simian immunodeficiency virus infections.
  Curr Opin HIV AIDS Volume: 7 Page(s): 71 - 78
  01/01/2012 Authors: Bosinger SE; Jacquelin B; Benecke A; Silvestri G; Mller-Trutwin M
• Cloning and analysis of sooty mangabey alternative coreceptors that support simian immunodeficiency virus SIVsmm entry independently of CCR5.
  J Virol Volume: 86 Page(s): 898 - 908
  01/01/2012 Authors: Elliott STC; Riddick NE; Francella N; Paiardini M; Vanderford TH; Li B; Apetrei C; Sodora DL; Derdeyn CA; Silvestri G
• Models of Protection Against HIV/SIV Avoiding AIDS in humans and monkeys Conclusions
  Page(s): 335 - 337
  01/01/2012 Authors: Pancino G; Silvestri G; Fowke KR
• The myeloid cytokine network in AIDS pathogenesis.
  Cytokine Growth Factor Rev Volume: 23 Page(s): 223 - 231
  01/01/2012 Authors: Mir KD; Mavigner M; Silvestri G
• B cell-helper neutrophils stimulate the diversification and production of immunoglobulin in the marginal zone of the spleen.
  Nat Immunol Volume: 13 Page(s): 170 - 180
  12/25/2011 Authors: Puga I; Cols M; Barra CM; He B; Cassis L; Gentile M; Comerma L; Chorny A; Shan M; Xu W
• Immunovirological analyses of chronically simian immunodeficiency virus SIVmnd-1- and SIVmnd-2-infected mandrills (Mandrillus sphinx).
  J Virol Volume: 85 Page(s): 13077 - 13087
  12/01/2011 Authors: Apetrei C; Sumpter B; Souquiere S; Chahroudi A; Makuwa M; Reed P; Ribeiro RM; Pandrea I; Roques P; Silvestri G
• Primate genomes for biomedicine.
  Nat Biotechnol Volume: 29 Page(s): 983 - 984
  11/08/2011 Authors: Bosinger SE; Johnson ZP; Silvestri G
• Depletion of CD4 T cells abrogates post-peak decline of viremia in SIV-infected rhesus macaques.
  J Clin Invest Volume: 121 Page(s): 4433 - 4445
  11/01/2011 Authors: Ortiz AM; Klatt NR; Li B; Yi Y; Tabb B; Hao XP; Sternberg L; Lawson B; Carnathan PM; Cramer EM
• Evidence for CD4 T-Cell Mediated Immune Control of Macrophage Infection in Rhesus Macaques Undergoing CD4+Lymphocyte Depletion Prior to SIV Infection
  Volume: 27 Page(s): A17 - A18
  10/01/2011 Authors: Ortiz A; Li B; Klatt NR; Lawson B; Ryzhova E; Carnathan P; Paiardini M; Else J; Gonzalez-Scarano F; Ratcliffe SJ
• No acquisition: a new ambition for HIV vaccine development?
  Curr Opin Virol Volume: 1 Page(s): 246 - 253
  10/01/2011 Authors: Lakhashe SK; Silvestri G; Ruprecht RM
• Plasmacytoid dendritic cells are recruited to the colorectum and contribute to immune activation during pathogenic SIV infection in rhesus macaques.
  Blood Volume: 118 Page(s): 2763 - 2773
  09/08/2011 Authors: Kwa S; Kannanganat S; Nigam P; Siddiqui M; Shetty RD; Armstrong W; Ansari A; Bosinger SE; Silvestri G; Amara RR
• CD4-like immunological function by CD4- T cells in multiple natural hosts of simian immunodeficiency virus.
  J Virol Volume: 85 Page(s): 8702 - 8708
  09/01/2011 Authors: Vinton C; Klatt NR; Harris LD; Briant JA; Sanders-Beer BE; Herbert R; Woodward R; Silvestri G; Pandrea I; Apetrei C
• Why don't CD8+ T cells reduce the lifespan of SIV-infected cells in vivo?
  PLoS Comput Biol Volume: 7 Page(s): e1002200
  09/01/2011 Authors: Elemans M; Seich Al Basatena N-K; Klatt NR; Gkekas C; Silvestri G; Asquith B
• Generalized immune activation and innate immune responses in simian immunodeficiency virus infection.
  Curr Opin HIV AIDS Volume: 6 Page(s): 411 - 418
  09/01/2011 Authors: Bosinger SE; Sodora DL; Silvestri G
• A NOVEL CCR5 MUTATION COMMON IN SOOTY MANGABEYS REVEALS SIVSMM INFECTION OF CCR5-NULL NATURAL HOSTS AND EFFICIENT ALTERNATIVE CORECEPTOR USE IN VIVO
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 40 Page(s): 253 - 253
  08/01/2011 Authors: Riddick NE; Elliott STC; Wey WC; Paiardini M; Silvestri G; Collman RG
• CCR5 EXPRESSION ON CD4+T CELLS AND NOT CD4 DOWNREGULATION IMPACTS THE EFFICACY OF SIVAGM MUCOSAL TRANSMISSION IN AFRICAN GREEN MONKEYS (AGMS)
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 40 Page(s): 256 - 256
  08/01/2011 Authors: Kuhrt D; Nusbaum R; Garlena R; Thanh N; Jorgensen MJ; Silvestri G; Kaplan J; Apetrei C; Pandrea I
• The evolution of infectious agents in relation to sex in animals and humans: brief discussions of some individual organisms.
  Volume: 1230 Page(s): 74 - 107
  08/01/2011 Authors: Reed DL; Currier RW; Walton SF; Conrad M; Sullivan SA; Carlton JM; Read TD; Severini A; Tyler S; Eberle R
• IL-21 PRODUCING CD4+T-CELLS ARE PREFERENTIALLY DEPLETED IN SIV-INFECTED RHESUS MACAQUES BUT PRESERVED IN SIV-INFECTED SOOTY MANGABEYS
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 40 Page(s): 252 - 253
  08/01/2011 Authors: Reyes-Aville E; Cervasi B; Else J; Silvestri G; Paiardini M
• Differential innate immune responses to low or high dose oral SIV challenge in Rhesus macaques.
  Curr HIV Res Volume: 9 Page(s): 276 - 288
  07/01/2011 Authors: Durudas A; Chen H-L; Gasper MA; Sundaravaradan V; Milush JM; Silvestri G; Johnson W; Giavedoni LD; Sodora DL
• Low levels of SIV infection in sooty mangabey central memory CD T cells are associated with limited CCR5 expression.
  Nat Med Volume: 17 Page(s): 830 - 836
  06/26/2011 Authors: Paiardini M; Cervasi B; Reyes-Aviles E; Micci L; Ortiz AM; Chahroudi A; Vinton C; Gordon SN; Bosinger SE; Francella N
• Mother-to-infant transmission of simian immunodeficiency virus is rare in sooty mangabeys and is associated with low viremia.
  J Virol Volume: 85 Page(s): 5757 - 5763
  06/01/2011 Authors: Chahroudi A; Meeker T; Lawson B; Ratcliffe S; Else J; Silvestri G
• Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque.
  J Clin Invest Volume: 121 Page(s): 2391 - 2400
  06/01/2011 Authors: Rotger M; Dalmau J; Rauch A; McLaren P; Bosinger SE; Martinez R; Sandler NG; Roque A; Liebner J; Battegay M
• Viral CTL escape mutants are generated in lymph nodes and subsequently become fixed in plasma and rectal mucosa during acute SIV infection of macaques.
  PLoS Pathog Volume: 7 Page(s): e1002048
  05/01/2011 Authors: Vanderford TH; Bleckwehl C; Engram JC; Dunham RM; Klatt NR; Feinberg MB; Garber DA; Betts MR; Silvestri G
• HIV persistence in the gut mucosa of HIV-infected subjects undergoing antiretroviral therapy correlates with immune activation and increased levels of LPS.
  Curr HIV Res Volume: 9 Page(s): 148 - 153
  04/01/2011 Authors: d'Ettorre G; Paiardini M; Zaffiri L; Andreotti M; Ceccarelli G; Rizza C; Indinnimeo M; Vella S; Mastroianni CM; Silvestri G
• HIV-associated immune activation: from bench to bedside.
  AIDS Res Hum Retroviruses Volume: 27 Page(s): 355 - 364
  04/01/2011 Authors: d'Ettorre G; Paiardini M; Ceccarelli G; Silvestri G; Vullo V
• Cumulative mechanisms of lymphoid tissue fibrosis and T cell depletion in HIV-1 and SIV infections.
  J Clin Invest Volume: 121 Page(s): 998 - 1008
  03/01/2011 Authors: Zeng M; Smith AJ; Wietgrefe SW; Southern PJ; Schacker TW; Reilly CS; Estes JD; Burton GF; Silvestri G; Lifson JD
• Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells.
  J Clin Invest Volume: 121 Page(s): 1102 - 1110
  03/01/2011 Authors: Milush JM; Mir KD; Sundaravaradan V; Gordon SN; Engram J; Cano CA; Reeves JD; Anton E; O'Neill E; Butler E
• Vaccine-induced T cells provide partial protection against high-dose rectal SIVmac239 challenge of rhesus macaques.
  Mol Ther Volume: 19 Page(s): 417 - 426
  02/01/2011 Authors: Lasaro MO; Haut LH; Zhou X; Xiang Z; Zhou D; Li Y; Giles-Davis W; Li H; Engram JC; Dimenna LJ
• Limited CD4+ T cell proliferation leads to preservation of CD4+ T cell counts in SIV-infected sooty mangabeys.
  Proc Biol Sci Volume: 277 Page(s): 3773 - 3781
  12/22/2010 Authors: Chan ML; Petravic J; Ortiz AM; Engram J; Paiardini M; Cromer D; Silvestri G; Davenport MP
• Disruption of intestinal CD4+ T cell homeostasis is a key marker of systemic CD4+ T cell activation in HIV-infected individuals.
  J Immunol Volume: 185 Page(s): 5169 - 5179
  11/01/2010 Authors: Gordon SN; Cervasi B; Odorizzi P; Silverman R; Aberra F; Ginsberg G; Estes JD; Paiardini M; Frank I; Silvestri G
• Systems biology analysis of CD8-lymphocyte depletion in SIV-infected rhesus macaques
  Volume: 26 Page(s): A114 - A115
  10/01/2010 Authors: Bosinger SE; Klatt NR; Silvestri G
• Nonpathogenic SIV infection of Sooty Mangabeys is not associated with high levels of autologous neutralizing antibodies
  Volume: 26 Page(s): A23 - A24
  10/01/2010 Authors: Li B; Stefano-Cole K; Kuhrt DM; Gordon SN; Else JG; Mulenga J; Allen S; Sodora DL; Silvestri G; Derdeyn CA
• Characterisation of Lactobacillus helveticus strains producing antihypertensive peptides by RAPD and inverse-PCR of IS elements.
  Benef Microbes Volume: 1 Page(s): 229 - 242
  09/01/2010 Authors: Aquilanti L; Carbini A; Strappati R; Santarelli S; Silvestri G; Garofalo C; Clementi F
• Interleukin-7 inHIV pathogenesis andtherapy.
  Eur Cytokine Netw Volume: 21 Page(s): 202 - 207
  09/01/2010 Authors: Chahroudi A; Silvestri G
• Similar impact of CD8+ T cell responses on early virus dynamics during SIV infections of rhesus macaques and sooty mangabeys.
  PLoS Comput Biol Volume: 6
  08/26/2010 Authors: Kouyos RD; Gordon SN; Staprans SI; Silvestri G; Regoes RR
• A novel CCR5 mutation common in sooty mangabeys reveals SIVsmm infection of CCR5-null natural hosts and efficient alternative coreceptor use in vivo.
  PLoS Pathog Volume: 6 Page(s): e1001064
  08/26/2010 Authors: Riddick NE; Hermann EA; Loftin LM; Elliott ST; Wey WC; Cervasi B; Taaffe J; Engram JC; Li B; Else JG
• Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections.
  PLoS Pathog Volume: 6 Page(s): e1001052
  08/19/2010 Authors: Estes JD; Harris LD; Klatt NR; Tabb B; Pittaluga S; Paiardini M; Barclay GR; Smedley J; Pung R; Oliveira KM
• Lineage-specific T-cell reconstitution following in vivo CD4+ and CD8+ lymphocyte depletion in nonhuman primates.
  Blood Volume: 116 Page(s): 748 - 758
  08/05/2010 Authors: Engram JC; Cervasi B; Borghans JAM; Klatt NR; Gordon SN; Chahroudi A; Else JG; Mittler RS; Sodora DL; de Boer RJ
• Downregulation of robust acute type I interferon responses distinguishes nonpathogenic simian immunodeficiency virus (SIV) infection of natural hosts from pathogenic SIV infection of rhesus macaques.
  J Virol Volume: 84 Page(s): 7886 - 7891
  08/01/2010 Authors: Harris LD; Tabb B; Sodora DL; Paiardini M; Klatt NR; Douek DC; Silvestri G; Mller-Trutwin M; Vasile-Pandrea I; Apetrei C
• DAMAGED INTESTINAL EPITHELIAL INTEGRITY AND MICROBIAL TRANSLOCATION IN SIMIAN IMMUNODEFICIENCY VIRUS INFECTIONS
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 39 Page(s): 275 - 275
  08/01/2010 Authors: Harris LD; Pitaluga S; Silvestri G; Douek DC; Miller CJ; Haase AT; Lifson J; Brenchley JM; Estes JD
• Nonprogressive and progressive primate immunodeficiency lentivirus infections.
  Immunity Volume: 32 Page(s): 737 - 742
  06/25/2010 Authors: Brenchley JM; Silvestri G; Douek DC
• Nonpathogenic simian immunodeficiency virus infection of sooty mangabeys is not associated with high levels of autologous neutralizing antibodies.
  J Virol Volume: 84 Page(s): 6248 - 6253
  06/01/2010 Authors: Li B; Stefano-Cole K; Kuhrt DM; Gordon SN; Else JG; Mulenga J; Allen S; Sodora DL; Silvestri G; Derdeyn CA
• HIV-induced abnormalities in myelopoiesis and their recovery following antiretroviral therapy.
  Curr HIV Res Volume: 8 Page(s): 336 - 339
  06/01/2010 Authors: Costantini A; Giuliodoro S; Butini L; Silvestri G; Leoni P; Montroni M
• A five-year longitudinal analysis of sooty mangabeys naturally infected with simian immunodeficiency virus reveals a slow but progressive decline in CD4+ T-cell count whose magnitude is not predicted by viral load or immune activation.
  J Virol Volume: 84 Page(s): 5476 - 5484
  06/01/2010 Authors: Taaffe J; Chahroudi A; Engram J; Sumpter B; Meeker T; Ratcliffe S; Paiardini M; Else J; Silvestri G
• HIV, mucosal tissues, and T helper 17 cells: where we come from, where we are, and where we go from here.
  Curr Opin HIV AIDS Volume: 5 Page(s): 111 - 113
  03/01/2010 Authors: Sodora DL; Silvestri G
• CD8+ lymphocytes control viral replication in SIVmac239-infected rhesus macaques without decreasing the lifespan of productively infected cells.
  PLoS Pathog Volume: 6 Page(s): e1000747
  01/29/2010 Authors: Klatt NR; Shudo E; Ortiz AM; Engram JC; Paiardini M; Lawson B; Miller MD; Else J; Pandrea I; Estes JD
• Elevated levels of innate immune modulators in lymph nodes and blood are associated with more-rapid disease progression in simian immunodeficiency virus-infected monkeys.
  J Virol Volume: 83 Page(s): 12229 - 12240
  12/01/2009 Authors: Durudas A; Milush JM; Chen H-L; Engram JC; Silvestri G; Sodora DL
• Nonpathogenic SIV infection of African green monkeys induces a strong but rapidly controlled type I IFN response.
  J Clin Invest Volume: 119 Page(s): 3544 - 3555
  12/01/2009 Authors: Jacquelin B; Mayau V; Targat B; Liovat A-S; Kunkel D; Petitjean G; Dillies M-A; Roques P; Butor C; Silvestri G
• Global genomic analysis reveals rapid control of a robust innate response in SIV-infected sooty mangabeys.
  J Clin Invest Volume: 119 Page(s): 3556 - 3572
  12/01/2009 Authors: Bosinger SE; Li Q; Gordon SN; Klatt NR; Duan L; Xu L; Francella N; Sidahmed A; Smith AJ; Cramer EM
• Monkeying around with HIV vaccines: using rhesus macaques to define 'gatekeepers' for clinical trials.
  Nat Rev Immunol Volume: 9 Page(s): 717 - 728
  10/01/2009 Authors: Shedlock DJ; Silvestri G; Weiner DB
• Microbiological and technological characterization of sourdoughs destined for bread-making with barley flour.
  Food Microbiol Volume: 26 Page(s): 744 - 753
  10/01/2009 Authors: Zannini E; Garofalo C; Aquilanti L; Santarelli S; Silvestri G; Clementi F
• Abnormalities of erythropoiesis during HIV-1 disease: a longitudinal analysis.
  J Acquir Immune Defic Syndr Volume: 52 Page(s): 70 - 74
  09/01/2009 Authors: Costantini A; Giuliodoro S; Butini L; Silvestri G; Leoni P; Montroni M
• Is the gut the major source of virus in early simian immunodeficiency virus infection?
  J Virol Volume: 83 Page(s): 7517 - 7523
  08/01/2009 Authors: Lay MDH; Petravic J; Gordon SN; Engram J; Silvestri G; Davenport MP
• Toward an AIDS vaccine: lessons from natural simian immunodeficiency virus infections of African nonhuman primate hosts.
  Nat Med Volume: 15 Page(s): 861 - 865
  08/01/2009 Authors: Sodora DL; Allan JS; Apetrei C; Brenchley JM; Douek DC; Else JG; Estes JD; Hahn BH; Hirsch VM; Kaur A
• Increased mortality and AIDS-like immunopathology in wild chimpanzees infected with SIVcpz.
  Nature Volume: 460 Page(s): 515 - 519
  07/23/2009 Authors: Keele BF; Jones JH; Terio KA; Estes JD; Rudicell RS; Wilson ML; Li Y; Learn GH; Beasley TM; Schumacher-Stankey J
• Vaccine-induced, simian immunodeficiency virus-specific CD8+ T cells reduce virus replication but do not protect from simian immunodeficiency virus disease progression.
  J Immunol Volume: 183 Page(s): 706 - 717
  07/01/2009 Authors: Engram JC; Dunham RM; Makedonas G; Vanderford TH; Sumpter B; Klatt NR; Ratcliffe SJ; Garg S; Paiardini M; McQuoid M
• IL-7 administration drives T cell-cycle entry and expansion in HIV-1 infection.
  Blood Volume: 113 Page(s): 6304 - 6314
  06/18/2009 Authors: Sereti I; Dunham RM; Spritzler J; Aga E; Proschan MA; Medvik K; Battaglia CA; Landay AL; Pahwa S; Fischl MA
• Adenovirus vector-induced immune responses in nonhuman primates: responses to prime boost regimens.
  J Immunol Volume: 182 Page(s): 6587 - 6599
  05/15/2009 Authors: Tatsis N; Lasaro MO; Lin S-W; Haut LH; Xiang ZQ; Zhou D; Dimenna L; Li H; Bian A; Abdulla S
• Immunopathogenesis of AIDS.
  Curr Infect Dis Rep Volume: 11 Page(s): 239 - 245
  05/01/2009 Authors: Ortiz AM; Silvestri G
• Conservation of Nef function across highly diverse lineages of SIVsmm.
  Retrovirology Volume: 6 Page(s): 36
  04/09/2009 Authors: Schmkel J; Li H; Bailes E; Schindler M; Silvestri G; Hahn BH; Apetrei C; Kirchhoff F
• Circulating monocytes in HIV-1-infected viremic subjects exhibit an antiapoptosis gene signature and virus- and host-mediated apoptosis resistance.
  J Immunol Volume: 182 Page(s): 4459 - 4470
  04/01/2009 Authors: Giri MS; Nebozyhn M; Raymond A; Gekonge B; Hancock A; Creer S; Nicols C; Yousef M; Foulkes AS; Mounzer K
• Enhancing SIV-specific immunity in vivo by PD-1 blockade.
  Nature Volume: 458 Page(s): 206 - 210
  03/12/2009 Authors: Velu V; Titanji K; Zhu B; Husain S; Pladevega A; Lai L; Vanderford TH; Chennareddi L; Silvestri G; Freeman GJ
• T-cell phenotypic and functional changes associated with social subordination and gene polymorphisms in the serotonin reuptake transporter in female rhesus monkeys.
  Brain Behav Immun Volume: 23 Page(s): 286 - 293
  02/01/2009 Authors: Paiardini M; Hoffman J; Cervasi B; Ortiz AM; Stroud F; Silvestri G; Wilson ME
• Bone marrow-based homeostatic proliferation of mature T cells in nonhuman primates: implications for AIDS pathogenesis.
  Blood Volume: 113 Page(s): 612 - 621
  01/15/2009 Authors: Paiardini M; Cervasi B; Engram JC; Gordon SN; Klatt NR; Muthukumar A; Else J; Mittler RS; Staprans SI; Sodora DL
• Preserved adaptive immune responses and limited immune activation in CD4-low SIV-positive sooty mangabeys
  RETROVIROLOGY Volume: 6
  01/01/2009 Authors: Mir KD; Milush JM; Brenchley JM; Reeves JD; Gordon SN; Else JG; O'Neill E; Silvestri G; Sodora DL
• CCL3L Copy number variation and the co-evolution of primate and viral genomes.
  PLoS Genet Volume: 5 Page(s): e1000359
  01/01/2009 Authors: Gornalusse G; Mummidi S; He W; Silvestri G; Bamshad M; Ahuja SK
• AIDS in african nonhuman primate hosts of SIVs: a new paradigm of SIV infection.
  Curr HIV Res Volume: 7 Page(s): 57 - 72
  01/01/2009 Authors: Pandrea I; Silvestri G; Apetrei C
• Immunity in natural SIV infections.
  J Intern Med Volume: 265 Page(s): 97 - 109
  01/01/2009 Authors: Silvestri G
• Extensive intestinal damage underlies microbial translocation in the GI tract of chronically SIV-infected Rhesus macaques
  RETROVIROLOGY Volume: 6
  01/01/2009 Authors: Harris LD; Estes JD; Klatt NR; Taft B; Barclay R; Douek DC; Silvestri G; Liffson J; Brenchley J
• Lessons learned from the natural hosts of HIV-related viruses.
  Annu Rev Med Volume: 60 Page(s): 485 - 495
  01/01/2009 Authors: Paiardini M; Pandrea I; Apetrei C; Silvestri G
• Rapid loss of dendritic cell and monocyte responses to TLR ligands following venipuncture.
  J Immunol Methods Volume: 339 Page(s): 132 - 140
  12/31/2008 Authors: Meier A; Fisher A; Sidhu HK; Chang JJ; Wen TF; Streeck H; Alter G; Silvestri G; Altfeld M
• Human immunodeficiency virus type 1 Nef induces programmed death 1 expression through a p38 mitogen-activated protein kinase-dependent mechanism.
  J Virol Volume: 82 Page(s): 11536 - 11544
  12/01/2008 Authors: Muthumani K; Choo AY; Shedlock DJ; Laddy DJ; Sundaram SG; Hirao L; Wu L; Thieu KP; Chung CW; Lankaraman KM
• AIDS pathogenesis: a tale of two monkeys.
  J Med Primatol Volume: 37 Suppl 2 Page(s): 6 - 12
  12/01/2008 Authors: Silvestri G
• Mode of transmission affects the sensitivity of human immunodeficiency virus type 1 to restriction by rhesus TRIM5alpha.
  J Virol Volume: 82 Page(s): 11117 - 11128
  11/01/2008 Authors: Richardson MW; Carroll RG; Stremlau M; Korokhov N; Humeau LM; Silvestri G; Sodroski J; Riley JL
• Transcriptional Profiling of the Host Response to SIV Infection in Sooty Mangabeys and Rhesus Macaques
  Volume: 24 Page(s): 28 - 28
  10/01/2008 Authors: Bosinger SE; Gordon SN; Danesh A; Sidahmed A; Ran L; Xu L; Klucking S; Strobert E; Staprans SI; Silvestri G
• Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections.
  Blood Volume: 112 Page(s): 2826 - 2835
  10/01/2008 Authors: Brenchley JM; Paiardini M; Knox KS; Asher AI; Cervasi B; Asher TE; Scheinberg P; Price DA; Hage CA; Kholi LM
• Into the wild: simian immunodeficiency virus (SIV) infection in natural hosts.
  Trends Immunol Volume: 29 Page(s): 419 - 428
  09/01/2008 Authors: Pandrea I; Sodora DL; Silvestri G; Apetrei C
• Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infection.
  PLoS Pathog Volume: 4 Page(s): e1000107
  07/18/2008 Authors: Schindler M; Schmkel J; Specht A; Li H; Mnch J; Khalid M; Sodora DL; Hahn BH; Silvestri G; Kirchhoff F
• PCR-DGGE analysis of lactic acid bacteria and yeast dynamics during the production processes of three varieties of Panettone.
  J Appl Microbiol Volume: 105 Page(s): 243 - 254
  07/01/2008 Authors: Garofalo C; Silvestri G; Aquilanti L; Clementi F
• Paucity of CD4+ CCR5+ T cells may prevent transmission of simian immunodeficiency virus in natural nonhuman primate hosts by breast-feeding.
  J Virol Volume: 82 Page(s): 5501 - 5509
  06/01/2008 Authors: Pandrea I; Onanga R; Souquiere S; Mouinga-Ondme A; Bourry O; Makuwa M; Rouquet P; Silvestri G; Simon F; Roques P
• Availability of activated CD4+ T cells dictates the level of viremia in naturally SIV-infected sooty mangabeys.
  J Clin Invest Volume: 118 Page(s): 2039 - 2049
  06/01/2008 Authors: Klatt NR; Villinger F; Bostik P; Gordon SN; Pereira L; Engram JC; Mayne A; Dunham RM; Lawson B; Ratcliffe SJ
• Early resolution of acute immune activation and induction of PD-1 in SIV-infected sooty mangabeys distinguishes nonpathogenic from pathogenic infection in rhesus macaques.
  J Immunol Volume: 180 Page(s): 6798 - 6807
  05/15/2008 Authors: Estes JD; Gordon SN; Zeng M; Chahroudi AM; Dunham RM; Staprans SI; Reilly CS; Silvestri G; Haase AT
• Is Nef the elusive cause of HIV-associated hematopoietic dysfunction?
  J Clin Invest Volume: 118 Page(s): 1622 - 1625
  05/01/2008 Authors: Kirchhoff F; Silvestri G
• CD127 and CD25 expression defines CD4+ T cell subsets that are differentially depleted during HIV infection.
  J Immunol Volume: 180 Page(s): 5582 - 5592
  04/15/2008 Authors: Dunham RM; Cervasi B; Brenchley JM; Albrecht H; Weintrob A; Sumpter B; Engram J; Gordon S; Klatt NR; Frank I
• Short-lived infected cells support virus replication in sooty mangabeys naturally infected with simian immunodeficiency virus: implications for AIDS pathogenesis.
  J Virol Volume: 82 Page(s): 3725 - 3735
  04/01/2008 Authors: Gordon SN; Dunham RM; Engram JC; Estes J; Wang Z; Klatt NR; Paiardini M; Pandrea IV; Apetrei C; Sodora DL
• Simian immunodeficiency virus SIVagm dynamics in African green monkeys.
  J Virol Volume: 82 Page(s): 3713 - 3724
  04/01/2008 Authors: Pandrea I; Ribeiro RM; Gautam R; Gaufin T; Pattison M; Barnes M; Monjure C; Stoulig C; Dufour J; Cyprian W
• Immune activation and AIDS pathogenesis.
  AIDS Volume: 22 Page(s): 439 - 446
  02/19/2008 Authors: Sodora DL; Silvestri G
• Gamma/Delta T-cell functional responses differ after pathogenic human immunodeficiency virus and nonpathogenic simian immunodeficiency virus infections.
  J Virol Volume: 82 Page(s): 1155 - 1165
  02/01/2008 Authors: Kosub DA; Lehrman G; Milush JM; Zhou D; Chacko E; Leone A; Gordon S; Silvestri G; Else JG; Keiser P
• Early divergence in lymphoid tissue apoptosis between pathogenic and nonpathogenic simian immunodeficiency virus infections of nonhuman primates.
  J Virol Volume: 82 Page(s): 1175 - 1184
  02/01/2008 Authors: Cumont M-C; Diop O; Vaslin B; Elbim C; Viollet L; Monceaux V; Lay S; Silvestri G; Le Grand R; Mller-Trutwin M
• Mucosal immune dysfunction in AIDS pathogenesis.
  AIDS Rev Volume: 10 Page(s): 36 - 46
  01/01/2008 Authors: Paiardini M; Frank I; Pandrea I; Apetrei C; Silvestri G
• CD4+ CCR5+ T-cell dynamics during simian immunodeficiency virus infection of Chinese rhesus macaques.
  J Virol Volume: 81 Page(s): 13865 - 13875
  12/01/2007 Authors: Monceaux V; Viollet L; Petit F; Cumont MC; Kaufmann GR; Aubertin AM; Hurtrel B; Silvestri G; Estaquier J
• The microbial ecology of a typical Italian salami during its natural fermentation.
  Int J Food Microbiol Volume: 120 Page(s): 136 - 145
  11/30/2007 Authors: Aquilanti L; Santarelli S; Silvestri G; Osimani A; Petruzzelli A; Clementi F
• Investigation of the microbial ecology of Ciauscolo, a traditional Italian salami, by culture-dependent techniques and PCR-DGGE.
  Meat Sci Volume: 77 Page(s): 413 - 423
  11/01/2007 Authors: Silvestri G; Santarelli S; Aquilanti L; Beccaceci A; Osimani A; Tonucci F; Clementi F
• Understanding the benign nature of SIV infection in natural hosts.
  J Clin Invest Volume: 117 Page(s): 3148 - 3154
  11/01/2007 Authors: Silvestri G; Paiardini M; Pandrea I; Lederman MM; Sodora DL
• Phenotypic, genotypic and technological characterization of predominant lactic acid bacteria in Pecorino cheese from central Italy.
  J Appl Microbiol Volume: 103 Page(s): 948 - 960
  10/01/2007 Authors: Aquilanti L; Silvestri G; Zannini E; Osimani A; Santarelli S; Clementi F
• Severe depletion of mucosal CD4+ T cells in AIDS-free simian immunodeficiency virus-infected sooty mangabeys.
  J Immunol Volume: 179 Page(s): 3026 - 3034
  09/01/2007 Authors: Gordon SN; Klatt NR; Bosinger SE; Brenchley JM; Milush JM; Engram JC; Dunham RM; Paiardini M; Klucking S; Danesh A
• Acute loss of intestinal CD4+ T cells is not predictive of simian immunodeficiency virus virulence.
  J Immunol Volume: 179 Page(s): 3035 - 3046
  09/01/2007 Authors: Pandrea IV; Gautam R; Ribeiro RM; Brenchley JM; Butler IF; Pattison M; Rasmussen T; Marx PA; Silvestri G; Lackner AA
• Virally induced CD4+ T cell depletion is not sufficient to induce AIDS in a natural host.
  J Immunol Volume: 179 Page(s): 3047 - 3056
  09/01/2007 Authors: Milush JM; Reeves JD; Gordon SN; Zhou D; Muthukumar A; Kosub DA; Chacko E; Giavedoni LD; Ibegbu CC; Cole KS
• Virus subtype-specific features of natural simian immunodeficiency virus SIVsmm infection in sooty mangabeys.
  J Virol Volume: 81 Page(s): 7913 - 7923
  08/01/2007 Authors: Apetrei C; Gautam R; Sumpter B; Carter AC; Gaufin T; Staprans SI; Else J; Barnes M; Cao R; Garg S
• Depletion of CD8+ cells in sooty mangabey monkeys naturally infected with simian immunodeficiency virus reveals limited role for immune control of virus replication in a natural host species.
  J Immunol Volume: 178 Page(s): 8002 - 8012
  06/15/2007 Authors: Barry AP; Silvestri G; Safrit JT; Sumpter B; Kozyr N; McClure HM; Staprans SI; Feinberg MB
• In vitro characterization of primary SIVsmm isolates belonging to different lineages. In vitro growth on rhesus macaque cells is not predictive for in vivo replication in rhesus macaques.
  Virology Volume: 362 Page(s): 257 - 270
  06/05/2007 Authors: Gautam R; Carter AC; Katz N; Butler IF; Barnes M; Hasegawa A; Ratterree M; Silvestri G; Marx PA; Hirsch VM
• Isolation and molecular characterization of antibiotic-resistant lactic acid bacteria from poultry and swine meat products.
  J Food Prot Volume: 70 Page(s): 557 - 565
  03/01/2007 Authors: Aquilanti L; Garofalo C; Osimani A; Silvestri G; Vignaroli C; Clementi F
• Correlates of preserved CD4(+) T cell homeostasis during natural, nonpathogenic simian immunodeficiency virus infection of sooty mangabeys: implications for AIDS pathogenesis.
  J Immunol Volume: 178 Page(s): 1680 - 1691
  02/01/2007 Authors: Sumpter B; Dunham R; Gordon S; Engram J; Hennessy M; Kinter A; Paiardini M; Cervasi B; Klatt N; McClure H
• Paucity of CD4+CCR5+ T cells is a typical feature of natural SIV hosts.
  Blood Volume: 109 Page(s): 1069 - 1076
  02/01/2007 Authors: Pandrea I; Apetrei C; Gordon S; Barbercheck J; Dufour J; Bohm R; Sumpter B; Roques P; Marx PA; Hirsch VM
• Microbial translocation is a cause of systemic immune activation in chronic HIV infection.
  Nat Med Volume: 12 Page(s): 1365 - 1371
  12/01/2006 Authors: Brenchley JM; Price DA; Schacker TW; Asher TE; Silvestri G; Rao S; Kazzaz Z; Bornstein E; Lambotte O; Altmann D
• Fludarabine delivery by autologous red blood cells induces macrophage depletion in chronically SIV-infected Sooty Mangabeys.
  J Control Release Volume: 116 Page(s): e45 - e47
  11/28/2006 Authors: Magnani M; Paiardini M; Cervasi B; Serafini S; Fraternale A; Silvestri G
• Administration of fludarabine-loaded autologous red blood cells in simian immunodeficiency virus-infected sooty mangabeys depletes pSTAT-1-expressing macrophages and delays the rebound of viremia after suspension of antiretroviral therapy.
  J Virol Volume: 80 Page(s): 10335 - 10345
  11/01/2006 Authors: Cervasi B; Paiardini M; Serafini S; Fraternale A; Menotta M; Engram J; Lawson B; Staprans SI; Piedimonte G; Perno CF
• Impaired in-vitro growth of megakaryocytic colonies derived from CD34 cells of HIV-1-infected patients with active viral replication.
  AIDS Volume: 20 Page(s): 1713 - 1720
  08/22/2006 Authors: Costantini A; Giuliodoro S; Mancini S; Butini L; Regnery CM; Silvestri G; Greco F; Leoni P; Montroni M
• Non-pathogenic SIV-infection of mandrillus sphinx is characterized by high viral load, moderate CD4+ T cell depletion, and low levels of T cell activation and apoptosis
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 35 Page(s): 294 - 295
  08/01/2006 Authors: Sumpter B; Souquiere S; Makuwa M; Reed T; Roques P; Silvestri G
• Simian immunodeficiency viruses replication dynamics in African non-human primate hosts: common patterns and species-specific differences.
  J Med Primatol Volume: 35 Page(s): 194 - 201
  08/01/2006 Authors: Pandrea I; Silvestri G; Onanga R; Veazey RS; Marx PA; Hirsch V; Apetrei C
• Relative depletion of CD4+ T cells from the mucosal associated lymphoid tissue (MALT) during non-pathogenic SIV infection of Sooty Mangabeys
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 35 Page(s): 275 - 276
  08/01/2006 Authors: Gordon SN; Engram JC; Dunham RM; Strobert EA; Pandrea IV; Staprans SI; Silvestri G
• Expanded coreceptor usage (r5/x4) correlates with AIDS defining CD4 T cell levels during nonpathogenic SIVsm infection of sooty mangabeys
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 35 Page(s): 275 - 275
  08/01/2006 Authors: Milush JM; Reeves J; Zhou D; Muthukumar A; Chacko E; Paiardini M; Cole KAS; Barry AP; Staprans S; Silvestri G
• Securing the future of free-ranging sooty mangabeys through biomedical research
  AMERICAN JOURNAL OF PRIMATOLOGY Volume: 68 Page(s): 38 - 38
  08/01/2006 Authors: Else JG; Staprans SI; Silvestri G; Apetrei C; McGraw WS
• The AIDS resistance of naturally SIV-infected sooty mangabeys is independent of cellular immunity to the virus.
  Blood Volume: 108 Page(s): 209 - 217
  07/01/2006 Authors: Dunham R; Pagliardini P; Gordon S; Sumpter B; Engram J; Moanna A; Paiardini M; Mandl JN; Lawson B; Garg S
• Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.
  Cell Volume: 125 Page(s): 1055 - 1067
  06/16/2006 Authors: Schindler M; Mnch J; Kutsch O; Li H; Santiago ML; Bibollet-Ruche F; Mller-Trutwin MC; Novembre FJ; Peeters M; Courgnaud V
• Kuru experiments triggered the emergence of pathogenic SIVmac.
  AIDS Volume: 20 Page(s): 317 - 321
  02/14/2006 Authors: Apetrei C; Lerche NW; Pandrea I; Gormus B; Silvestri G; Kaur A; Robertson DL; Hardcastle J; Lackner AA; Marx PA
• Why are pathogenic SIV and HIV infections characterized by high level immune activation when other chronic virus infection are not? Lessons from nonpathogenic SIV infection in natural host species
  RETROVIROLOGY Volume: 3
  01/01/2006 Authors: Staprans S; Klucking S; Silvestri G; Chavan R; Barry A; Feinberg M
• Perturbations of cell cycle control in T cells contribute to the different outcomes of simian immunodeficiency virus infection in rhesus macaques and sooty mangabeys.
  J Virol Volume: 80 Page(s): 634 - 642
  01/01/2006 Authors: Paiardini M; Cervasi B; Sumpter B; McClure HM; Sodora DL; Magnani M; Staprans SI; Piedimonte G; Silvestri G
• Nef-mediated TCR-CD3 and MHC-I down-modulation prevents CD4+T cell depletion in natural SIV infection
  RETROVIROLOGY Volume: 3
  01/01/2006 Authors: Schindler M; Muench J; Kutsch O; Li H; Santiago ML; Bibollet-Ruche F; Mueller-Trutwin MC; Novembre FJ; Peeters M; Courgnaud V
• Timely triggering of homeostatic mechanisms involved in the regulation of T-cell levels in SIVsm-infected sooty mangabeys.
  Blood Volume: 106 Page(s): 3839 - 3845
  12/01/2005 Authors: Muthukumar A; Zhou D; Paiardini M; Barry AP; Cole KS; McClure HM; Staprans SI; Silvestri G; Sodora DL
• Naturally SIV-infected sooty mangabeys: are we closer to understanding why they do not develop AIDS?
  J Med Primatol Volume: 34 Page(s): 243 - 252
  10/01/2005 Authors: Silvestri G
• Vaccinia virus tropism for primary hematolymphoid cells is determined by restricted expression of a unique virus receptor.
  J Virol Volume: 79 Page(s): 10397 - 10407
  08/01/2005 Authors: Chahroudi A; Chavan R; Kozyr N; Waller EK; Silvestri G; Feinberg MB
• Viral and host factors in the pathogenesis of HIV infection.
  Curr Opin Immunol Volume: 17 Page(s): 366 - 373
  08/01/2005 Authors: Derdeyn CA; Silvestri G
• Apoptosis in SIV infection.
  Cell Death Differ Volume: 12 Suppl 1 Page(s): 979 - 990
  08/01/2005 Authors: Hurtrel B; Petit F; Arnoult D; Mller-Trutwin M; Silvestri G; Estaquier J
• Differentiation of CD8 T cells in response to acute and chronic viral infections: implications for HIV vaccine development.
  Curr Drug Targets Infect Disord Volume: 5 Page(s): 121 - 129
  06/01/2005 Authors: Miller JD; Masopust D; Wherry EJ; Kaech S; Silvestri G; Ahmed R
• Divergent host responses during primary simian immunodeficiency virus SIVsm infection of natural sooty mangabey and nonnatural rhesus macaque hosts.
  J Virol Volume: 79 Page(s): 4043 - 4054
  04/01/2005 Authors: Silvestri G; Fedanov A; Germon S; Kozyr N; Kaiser WJ; Garber DA; McClure H; Feinberg MB; Staprans SI
• Loss of CD127 expression defines an expansion of effector CD8+ T cells in HIV-infected individuals.
  J Immunol Volume: 174 Page(s): 2900 - 2909
  03/01/2005 Authors: Paiardini M; Cervasi B; Albrecht H; Muthukumar A; Dunham R; Gordon S; Radziewicz H; Piedimonte G; Magnani M; Montroni M
• CD4+ T-cell depletion in HIV infection: killed by friendly fire?
  Curr HIV/AIDS Rep Volume: 2 Page(s): 16 - 23
  02/01/2005 Authors: Moanna A; Dunham R; Paiardini M; Silvestri G
• Enhanced SIV replication and accelerated progression to AIDS in macaques primed to mount a CD4 T cell response to the SIV envelope protein.
  Proc Natl Acad Sci U S A Volume: 101 Page(s): 13026 - 13031
  08/31/2004 Authors: Staprans SI; Barry AP; Silvestri G; Safrit JT; Kozyr N; Sumpter B; Nguyen H; McClure H; Montefiori D; Cohen JI
• Prospects for an AIDS vaccine: three big questions, no easy answers.
  Lancet Infect Dis Volume: 4 Page(s): 397 - 413
  07/01/2004 Authors: Garber DA; Silvestri G; Feinberg MB
• Roles of target cells and virus-specific cellular immunity in primary simian immunodeficiency virus infection.
  J Virol Volume: 78 Page(s): 4866 - 4875
  05/01/2004 Authors: Regoes RR; Antia R; Garber DA; Silvestri G; Feinberg MB; Staprans SI
• Blockade of T cell costimulation reveals interrelated actions of CD4+ and CD8+ T cells in control of SIV replication.
  J Clin Invest Volume: 113 Page(s): 836 - 845
  03/01/2004 Authors: Garber DA; Silvestri G; Barry AP; Fedanov A; Kozyr N; McClure H; Montefiori DC; Larsen CP; Altman JD; Staprans SI
• Early correction of cell cycle perturbations predicts the immunological response to therapy in HIV-infected patients.
  AIDS Volume: 18 Page(s): 393 - 402
  02/20/2004 Authors: Paiardini M; Cervasi B; Galati D; Dominici S; Albrecht H; Sfacteria A; Magnani M; Silvestri G; Piedimonte G
• Elevated interleukin-7 levels not sufficient to maintain T-cell homeostasis during simian immunodeficiency virus-induced disease progression.
  Blood Volume: 103 Page(s): 973 - 979
  02/01/2004 Authors: Muthukumar A; Wozniakowski A; Gauduin M-C; Paiardini M; McClure HM; Johnson RP; Silvestri G; Sodora DL
• Cell-cycle dysregulation in the immunopathogenesis of AIDS.
  Immunol Res Volume: 29 Page(s): 253 - 268
  01/01/2004 Authors: Paiardini M; Cervasi B; Dunham R; Sumpter B; Radziewicz H; Silvestri G
• Correlation between T-cell reconstitution and serum IL-7 levels post-hematopoietic progenitor stem cell transplant (HPSCT).
  Volume: 102 Page(s): 941A - 942A
  11/16/2003 Authors: Radziewicz HT; Sumpter B; Poindexter G; Paiardini M; Cervasi B; Muthukumar A; Sodora DL; Waller EK; Silvestri GG; Somani J
• Specific changes in the posttranslational regulation of nucleolin in lymphocytes from patients infected with human immunodeficiency virus.
  J Infect Dis Volume: 188 Page(s): 1483 - 1491
  11/15/2003 Authors: Galati D; Paiardini M; Cervasi B; Albrecht H; Bocchino M; Costantini A; Montroni M; Magnani M; Piedimonte G; Silvestri G
• Measuring T cell-mediated cytotoxicity using fluorogenic caspase substrates.
  Methods Volume: 31 Page(s): 120 - 126
  10/01/2003 Authors: Chahroudi A; Silvestri G; Feinberg MB
• Turnover of lymphocytes and conceptual paradigms in HIV infection.
  J Clin Invest Volume: 112 Page(s): 821 - 824
  09/01/2003 Authors: Silvestri G; Feinberg MB
• Effects of cryopreservation on lymphocyte immunophenotype and function.
  J Immunol Methods Volume: 278 Page(s): 145 - 155
  07/01/2003 Authors: Costantini A; Mancini S; Giuliodoro S; Butini L; Regnery CM; Silvestri G; Montroni M
• Nonpathogenic SIV infection of sooty mangabeys is characterized by limited bystander immunopathology despite chronic high-level viremia.
  Immunity Volume: 18 Page(s): 441 - 452
  03/01/2003 Authors: Silvestri G; Sodora DL; Koup RA; Paiardini M; O'Neil SP; McClure HM; Staprans SI; Feinberg MB
• Repeated cycles of alternate administration of fludarabine and Zidovudine plus Didanosine inhibits murine AIDS and reduces proviral DNA content in lymph nodes to undetectable levels.
  Virology Volume: 302 Page(s): 354 - 362
  10/25/2002 Authors: Fraternale A; Casabianca A; Orlandi C; Chiarantini L; Brandi G; Silvestri G; Magnani M
• Cell cycle dysregulation during HIV infection: perspectives of a target based therapy.
  Curr Drug Targets Immune Endocr Metabol Disord Volume: 2 Page(s): 53 - 61
  04/01/2002 Authors: Galati D; Bocchino M; Paiardini M; Cervasi B; Silvestri G; Piedimonte G
• T(S) cells and immune tolerance induction: a regulatory renaissance?
  Nat Immunol Volume: 3 Page(s): 215 - 217
  03/01/2002 Authors: Feinberg MB; Silvestri G
• Visualization and quantification of T cell-mediated cytotoxicity using cell-permeable fluorogenic caspase substrates.
  Nat Med Volume: 8 Page(s): 185 - 189
  02/01/2002 Authors: Liu L; Chahroudi A; Silvestri G; Wernett ME; Kaiser WJ; Safrit JT; Komoriya A; Altman JD; Packard BZ; Feinberg MB
• Exogenous interleukin-2 administration corrects the cell cycle perturbation of lymphocytes from human immunodeficiency virus-infected individuals.
  J Virol Volume: 75 Page(s): 10843 - 10855
  11/01/2001 Authors: Paiardini M; Galati D; Cervasi B; Cannavo G; Galluzzi L; Montroni M; Guetard D; Magnani M; Piedimonte G; Silvestri G
• Highly active antiretroviral therapy induces specific changes in effector and central memory T cell sub-populations.
  AIDS Volume: 15 Page(s): 1887 - 1890
  09/28/2001 Authors: Muoz-Calleja C; Costantini A; Silvestri G; Butini L; Regnery CM; Mancini S; Montroni M
• Abnormal intracellular kinetics of cell-cycle-dependent proteins in lymphocytes from patients infected with human immunodeficiency virus: a novel biologic link between immune activation, accelerated T-cell turnover, and high levels of apoptosis.
  Blood Volume: 97 Page(s): 1756 - 1764
  03/15/2001 Authors: Cannavo' G; Paiardini M; Galati D; Cervasi B; Montroni M; De Vico G; Guetard D; Bocchino ML; Picerno I; Magnani M
• The role of target cell availability and immune control in primary SIV replication
  FASEB JOURNAL Volume: 14 Page(s): A938 - A938
  04/20/2000 Authors: Perry L; Antia R; Silvestri G; Feinberg M; Staprans S
• Quantification of thymic function by measuring T cell receptor excision circles within peripheral blood and lymphoid tissues in monkeys.
  Eur J Immunol Volume: 30 Page(s): 1145 - 1153
  04/01/2000 Authors: Sodora DL; Douek DC; Silvestri G; Montgomery L; Rosenzweig M; Igarashi T; Bernacky B; Johnson RP; Feinberg MB; Martin MA
• Transient T cell receptor beta-chain variable region-specific expansions of CD4+ and CD8+ T cells during the early phase of pediatric human immunodeficiency virus infection: characterization of expanded cell populations by T cell receptor phenotyping.
  J Infect Dis Volume: 181 Page(s): 107 - 120
  01/01/2000 Authors: Soudeyns H; Champagne P; Holloway CL; Silvestri GU; Ringuette N; Samson J; Lapointe N; Skaly RP
• Unscheduled cyclin B expression and p34 cdc2 activation in T lymphocytes from HIV-infected patients.
  AIDS Volume: 13 Page(s): 1159 - 1164
  07/09/1999 Authors: Piedimonte G; Corsi D; Paiardini M; Cannav G; Ientile R; Picerno I; Montroni M; Silvestri G; Magnani M
• Early increase of CD4+ CD45RA+ and CD4+ CD95- cells with conserved repertoire induced by anti-retroviral therapy in HIV-infected patients.
  Clin Exp Immunol Volume: 111 Page(s): 3 - 11
  01/01/1998 Authors: Silvestri G; Munoz-Calleja C; Bagnarelli P; Piedimonte G; Clementi M; Montroni M
• CD8 plus CD16-CD56-CD95/Fas plus monoclonal (V beta 17) T-LGL leukemia associated with primary CNS involvement and poor response to therapy. A case report.
  BLOOD Volume: 90 Page(s): 3951 - 3951
  11/15/1997 Authors: Rupoli S; Silvestri G; Scortechini AR; DiBella P; Logullo F; Montroni M; Leoni P
• Oxidative protein damage and degradation in lymphocytes from patients infected with human immunodeficiency virus.
  Volume: 176 Page(s): 655 - 664
  09/01/1997 Authors: Piedimonte G; Guetard D; Magnani M; Corsi D; Picerno I; Spataro P; Kramer L; Montroni M; Silvestri G; Torres Roca JF
• Changes in CD8 cell subpopulations induced by antiretroviral therapy in human immunodeficiency virus infected patients.
  Viral Immunol Volume: 10 Page(s): 207 - 212
  01/01/1997 Authors: Silvestri G; Munoz C; Butini L; Bagnarelli P; Montroni M
• T-cell receptor V beta-specific expansions in children from HIV-infected mothers.
  AIDS Volume: 10 Page(s): 549 - 551
  05/01/1996 Authors: Silvestri G; Soudeyns H; Samson J; Denis F; Lapointe N; Skaly RP
• p24 antigenaemia and clinical response to zidovudine therapy.
  AIDS Volume: 7 Page(s): 434 - 435
  03/01/1993 Authors: Montroni M; Silvestri G; Butini L; Regnery C; Bartocci C; Buffarini F; Danieli G
• Phagocytosis reduces HIV-1 production in human monocytes/macrophages infected in vitro.
  Arch Virol Volume: 130 Page(s): 463 - 469
  01/01/1993 Authors: Piedimonte G; Montroni M; Silvestri G; Silvotti L; Donatini A; Rossi L; Borghetti AF; Magnani M
• p24 antigenaemia as a predictor of good immunological responsiveness to zidovudine therapy in asymptomatic HIV infection.
  AIDS Volume: 6 Page(s): 338 - 339
  03/01/1992 Authors: Montroni M; Silvestri G; Butini L; Bartocci C; Regnery C; Danieli G