Jack Arbiser MD/PhD
Academic Appointment
Education
Degrees
- BS, MS from Emory University
- PhD from Harvard Medical School
- MD from Harvard Medical School
Research
Focus
- Dr. Arbiser has studied the mechanisms of how oncogenes and tumor suppressor genes regulate angiogenesis and tumorigenesis. This work has resulted in the discovery of small molecule inhibitors of tumor growth, and a novel method of predicting tumor signaling based upon loss of tumor suppressor genes p53 and p16ink4a.
Publications
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The Carcinogenesis of the Human Scalp: An Immunometabolic-Centered View.
Int J Mol Sci Volume: 25
11/10/2024 Authors: Kaplan B; von Dannecker R; Arbiser JL -
Dibenzolium induces apoptosis and inhibits epithelial-mesenchymal transition (EMT) in bladder cancer cell lines.
Sci Rep Volume: 14 Page(s): 25501
10/26/2024 Authors: Jotatsu Y; Arbiser JL; Moriwaki M; Hirata Y; Takeda S; Takada I; Chen K-C; Sung S-Y; Shigemura K -
The Neolignan Honokiol and Its Synthetic Derivative Honokiol Hexafluoro Reduce Neuroinflammation and Cellular Senescence in Microglia Cells.
Cells Volume: 13
10/04/2024 Authors: Sasia C; Borgonetti V; Mancini C; Lori G; Arbiser JL; Taddei ML; Galeotti N -
Honokiol hexafluoro confers reversal of neuropathological markers of HIV infection in a murine SCID model.
Neurotherapeutics Volume: 21 Page(s): e00329
03/01/2024 Authors: Zhang Z; Scanlan A; Koneru R; Morrell CR; Reece MD; Edwards E; Roa S; Gavegnano C; Bimonte-Nelson H; Arbiser J -
Skin Barrier Function: The Interplay of Physical, Chemical, and Immunologic Properties.
Cells Volume: 12
11/30/2023 Authors: Baker P; Huang C; Radi R; Moll SB; Jules E; Arbiser JL -
Skp2: A new therapeutic target of psoriasis.
Br J Dermatol
11/30/2023 Authors: Wang Y; Arbiser JL -
Flavones provide resistance to DUX4-induced toxicity via an mTor-independent mechanism.
Cell Death Dis Volume: 14 Page(s): 749
11/16/2023 Authors: Cohen J; Huang S; Koczwara KE; Woods KT; Ho V; Woodman KG; Arbiser JL; Daman K; Lek M; Emerson CP -
Targeting histone deacetylase-3 blocked epithelial-mesenchymal plasticity and metastatic dissemination in gastric cancer.
Cell Biol Toxicol Volume: 39 Page(s): 1873 - 1896
10/01/2023 Authors: Wu S-M; Jan Y-J; Tsai S-C; Pan H-C; Shen C-C; Yang C-N; Lee S-H; Liu S-H; Shen L-W; Chiu C-S -
Ant Venom-Based Ceramide Therapy Is Effective Against Atopic Dermatitis In Vivo.
J Drugs Dermatol Volume: 22 Page(s): 1001 - 1006
10/01/2023 Authors: Leyva-Castillo JM; Huang C; Baker P; Bacsa J; Geha RS; Arbiser JL -
Use of TYK2 inhibitor to relieve reactive granulomatous dermatitis due to myelodysplastic syndrome.
JAAD Case Rep Volume: 40 Page(s): 41 - 44
10/01/2023 Authors: Huang C; Berghoff A; Arbiser JL -
MAVS is a double-edged sword.
Mol Ther Nucleic Acids Volume: 33 Page(s): 869 - 870
09/12/2023 Authors: Huang C; Arbiser JL -
Targeting the Vulnerabilities of Oncogene Activation.
Cancers (Basel) Volume: 15
06/27/2023 Authors: Huang C; Arbiser JL -
Honokiol Inhibits SARS-CoV-2 Replication in Cell Culture at a Post-Entry Step.
Microbiol Spectr Volume: 11 Page(s): e0327322
06/15/2023 Authors: Salgado-Benvindo C; Leijs AA; Thaler M; Tas A; Arbiser JL; Snijder EJ; van Hemert MJ -
Early Detection and Prognostic Assessment of Cutaneous Melanoma: Consensus on Optimal Practice and the Role of Gene Expression Profile Testing.
JAMA Dermatol Volume: 159 Page(s): 545 - 553
05/01/2023 Authors: Kashani-Sabet M; Leachman SA; Stein JA; Arbiser JL; Berry EG; Celebi JT; Curiel-Lewandrowski C; Ferris LK; Grant-Kels JM; Grossman D -
R-Propranolol Has Broad-Spectrum Anti-Coronavirus Activity and Suppresses Factors Involved in Pathogenic Angiogenesis.
Int J Mol Sci Volume: 24
02/27/2023 Authors: Thaler M; Salgado-Benvindo C; Leijs A; Tas A; Ninaber DK; Arbiser JL; Snijder EJ; van Hemert MJ -
Flavones provide resistance to DUX4-induced toxicity via an mTor-independent mechanism.
Res Sq
02/02/2023 Authors: Cohen J; Huang S; Koczwara K; Ho V; Woodman K; Lek A; Arbiser J; Lek M; DeSimone A -
Intralesional Chemotherapy for Prostate Cancer: In vivo Proof of Principle.
Oncology Volume: 101 Page(s): 645 - 654
01/01/2023 Authors: Jotatsu Y; Shigemura K; Arbiser JL; Moriwaki M; Hirata Y; Maeda K; Yang Y-M; Fujisawa M -
SIRT3 activation promotes enteric neurons survival and differentiation.
Sci Rep Volume: 12 Page(s): 22076
12/21/2022 Authors: Balasubramaniam A; Li G; Ramanathan A; Mwangi SM; Hart CM; Arbiser JL; Srinivasan S -
Aggravation of pulmonary fibrosis after knocking down the aryl hydrocarbon receptor in the insulin-like growth factor 1 receptor pathway.
Br J Pharmacol Volume: 179 Page(s): 3430 - 3451
07/01/2022 Authors: Wu S-M; Tsai J-J; Pan H-C; Arbiser JL; Elia L; Sheu M-L -
Targeting aberrant replication and DNA repair events for treating breast cancers.
Commun Biol Volume: 5 Page(s): 493
05/24/2022 Authors: Rajamanickam S; Park JH; Subbarayalu P; Timilsina S; Bates K; Yadav P; Nirzhor SSR; Eedunuri V; Mohammad TA; Jung KH -
Indolium 1 Exerts Activity against Vemurafenib-Resistant Melanoma In Vivo.
Antioxidants (Basel) Volume: 11
04/19/2022 Authors: Radi R; Huang C; Elsey J; Jung YH; Corces VG; Arbiser JL -
Introduction of Mutant GNAQ into Endothelial Cells Induces a Vascular Malformation Phenotype with Therapeutic Response to Imatinib.
Cancers (Basel) Volume: 14
01/14/2022 Authors: Sasaki M; Jung Y; North P; Elsey J; Choate K; Toussaint MA; Huang C; Radi R; Perricone AJ; Corces VG -
Editorial: Current challenges in inflammation and pain biology: The role of natural and synthetic compounds.
Front Physiol Volume: 13 Page(s): 1008538
01/01/2022 Authors: Fernandes ES; Ferro ES; Simo G; Alves de Gis G; Arbiser J; Pereira Costa SK -
Honokiol Acts as a Potent Anti-Fibrotic Agent in the Liver through Inhibition of TGF-1/SMAD Signaling and Autophagy in Hepatic Stellate Cells.
Int J Mol Sci Volume: 22
12/12/2021 Authors: Kataoka S; Umemura A; Okuda K; Taketani H; Seko Y; Nishikawa T; Yamaguchi K; Moriguchi M; Kanbara Y; Arbiser JL -
Mitochondrial Metabolism in Melanoma.
Cells Volume: 10
11/16/2021 Authors: Huang C; Radi RH; Arbiser JL -
Successful treatment of palmoplantar psoriasis with chemical peeling and gentian violet.
JAAD Case Rep Volume: 17 Page(s): 28 - 30
11/01/2021 Authors: Bubley JA; Alharthi M; Arbiser JL -
TH2 sensitization in the skin-gut-brain axis: How early-life Th2-mediated inflammation may negatively perpetuate developmental and psychologic abnormalities.
Pediatr Dermatol Volume: 38 Page(s): 1032 - 1039
09/01/2021 Authors: Jackson-Cowan L; Cole EF; Arbiser JL; Silverberg JI; Lawley LP -
Hyperleptinemia in obese state renders luminal breast cancers refractory to tamoxifen by coordinating a crosstalk between Med1, miR205 and ErbB.
NPJ Breast Cancer Volume: 7 Page(s): 105
08/13/2021 Authors: Nagalingam A; Siddharth S; Parida S; Muniraj N; Avtanski D; Kuppusamy P; Elsey J; Arbiser JL; Gyrffy B; Sharma D -
Claisened Hexafluoro Inhibits Metastatic Spreading of Amoeboid Melanoma Cells.
Cancers (Basel) Volume: 13
07/15/2021 Authors: Leo A; Pranzini E; Pietrovito L; Pardella E; Parri M; Cirri P; Bruno G; Calvani M; Peppicelli S; Torre E -
Pimozide and Imipramine Blue Exploit Mitochondrial Vulnerabilities and Reactive Oxygen Species to Cooperatively Target High Risk Acute Myeloid Leukemia.
Antioxidants (Basel) Volume: 10
06/15/2021 Authors: Wang Z; Mi T; Bradley HL; Metts J; Sabnis H; Zhu W; Arbiser J; Bunting KD -
Evaluation of a First-in-Class Proteasome Inhibitor in Patients With Moderate to Severe Rosacea.
J Drugs Dermatol Volume: 20 Page(s): 660 - 664
06/01/2021 Authors: Jackson JM; Coulon R; Arbiser JL -
Correction: da Costa et al. Establishment of a Temperature-Sensitive Model of Oncogene-Induced Senescence in Angiosarcoma Cells. Cancers 2020, 12, 395.
Cancers (Basel) Volume: 13
04/22/2021 Authors: da Costa A; Bonner MY; Rao S; Gilbert L; Sasaki M; Elsey J; MacKelfresh J; Arbiser JL -
Honokiol Prevents Non-Alcoholic Steatohepatitis-Induced Liver Cancer via EGFR Degradation through the Glucocorticoid Receptor-MIG6 Axis.
Cancers (Basel) Volume: 13
03/25/2021 Authors: Okuda K; Umemura A; Umemura S; Kataoka S; Taketani H; Seko Y; Nishikawa T; Yamaguchi K; Moriguchi M; Kanbara Y -
Liposome-Imipramine Blue Inhibits Sonic Hedgehog Medulloblastoma In Vivo.
Cancers (Basel) Volume: 13
03/11/2021 Authors: MacDonald TJ; Liu J; Yu B; Malhotra A; Munson J; Park JC; Wang K; Fei B; Bellamkonda R; Arbiser J -
Honokiol Bis-Dichloroacetate Is a Selective Allosteric Inhibitor of the Mitochondrial Chaperone TRAP1.
Antioxid Redox Signal Volume: 34 Page(s): 505 - 516
03/01/2021 Authors: Sanchez-Martin C; Menon D; Moroni E; Ferraro M; Masgras I; Elsey J; Arbiser JL; Colombo G; Rasola A -
Reuse of Molecules for Glioblastoma Therapy.
Pharmaceuticals (Basel) Volume: 14
01/28/2021 Authors: Koehler A; Karve A; Desai P; Arbiser J; Plas DR; Qi X; Read RD; Sasaki AT; Gawali VS; Toukam DK -
Inhibitors of cytoskeletal dynamics in malignant mesothelioma.
Oncotarget Volume: 11 Page(s): 4637 - 4647
12/15/2020 Authors: Reis K; Arbiser JL; Hjerpe A; Dobra K; Aspenstrm P -
Tris DBA ameliorates IgA nephropathy by blunting the activating signal of NLRP3 inflammasome through SIRT1- and SIRT3-mediated autophagy induction.
J Cell Mol Med Volume: 24 Page(s): 13609 - 13622
12/01/2020 Authors: Wu C-Y; Hua K-F; Yang S-R; Tsai Y-S; Yang S-M; Hsieh C-Y; Wu C-C; Chang J-F; Arbiser JL; Chang C-T -
Angiofibroma stimulation in a transgender person receiving gender-affirming testosterone.
JAAD Case Rep Volume: 6 Page(s): 1101 - 1103
10/01/2020 Authors: Bubley JA; Yeung H; Cole E; Amin M; Parker D; Arbiser JL -
Induction of remission in a patient with end-stage cutaneous T-cell lymphoma by concurrent use of radiation therapy, gentian violet, and mogamulizumab.
JAAD Case Rep Volume: 6 Page(s): 761 - 765
08/01/2020 Authors: Westergaard SA; Lechowicz MJ; Harrington M; Elsey J; Arbiser JL; Khan MK -
Establishment of a model of ras oncogene induced senescence in endothelial cells
Volume: 140 Page(s): S114 - S114
07/01/2020 Authors: Costa A; Teichmann M; Bonner M; Mackelfresh J; Gilbert L; Rao S; Arbiser J -
HONOKIOL, A NOVEL AGENT THAT PROMOTES ENTERIC NEURONAL DIFFERENTIATION AND PREVENTS NEURODEGENERATION
Volume: 158 Page(s): S268 - S268
05/01/2020 Authors: Li G; Ramanathan A; Raju AV; Mwangi SM; Hart CM; Arbiser J; Srinivasan S -
Overcoming acquired resistance of EGFR-mutant NSCLC cells to the third generation EGFR inhibitor, osimertinib, with the natural product honokiol.
Mol Oncol Volume: 14 Page(s): 882 - 895
04/01/2020 Authors: Zang H; Qian G; Arbiser J; Owonikoko TK; Ramalingam SS; Fan S; Sun S-Y -
Tris DBA Ameliorates Accelerated and Severe Lupus Nephritis in Mice by Activating Regulatory T Cells and Autophagy and Inhibiting the NLRP3 Inflammasome.
J Immunol Volume: 204 Page(s): 1448 - 1461
03/15/2020 Authors: Wu C-Y; Hua K-F; Chu C-L; Yang S-R; Arbiser JL; Yang S-S; Lin Y-C; Liu F-C; Yang S-M; Ka S-M -
Establishment of a Temperature-Sensitive Model of Oncogene-Induced Senescence in Angiosarcoma Cells.
Cancers (Basel) Volume: 12
02/08/2020 Authors: Costa AD; Bonner MY; Rao S; Gilbert L; Sasaki M; Elsey J; MacKelfresh J; Arbiser JL -
Induction of STK11-dependent cytoprotective autophagy in breast cancer cells upon honokiol treatment.
Cell Death Discov Volume: 6 Page(s): 81
01/01/2020 Authors: Muniraj N; Siddharth S; Shriver M; Nagalingam A; Parida S; Woo J; Elsey J; Gabrielson K; Gabrielson E; Arbiser JL -
Palladium-based nanoparticles for the treatment of advanced melanoma
Volume: 81 Page(s): AB98 - AB98
10/01/2019 Authors: Bubley J; Elsey J; Zhu L; Rao S; Sasaki M; Pollack B; Yang L; Arbiser JL -
The putative tribbles homolog 3 (TRIB3) activator honokiol suppresses lipogenesis, and exerts anti-proliferative as well as anti-inflammatory effects on human sebocytes
Volume: 139 Page(s): S319 - S319
09/01/2019 Authors: Toth K; Adam D; Arany J; Farago P; Arbiser JL; Zouboulis CC; Biro T; Olah A -
Tris DBA palladium is an orally available inhibitor of GNAQ mutant uveal melanoma in vivo.
Oncotarget Volume: 10 Page(s): 4424 - 4436
07/09/2019 Authors: Musi E; Schwartz GK; Yoo JH; Odelberg SJ; Li DY; Bonner MY; Selvakumar P; Rao S; Gilbert LC; Elsey J -
Topical Application of Cinnamaldehyde Promotes Faster Healing of Skin Wounds Infected with Pseudomonas aeruginosa.
Molecules Volume: 24
04/25/2019 Authors: Ferro TAF; Souza EB; Suarez MAM; Rodrigues JFS; Pereira DMS; Mendes SJF; Gonzaga LF; Machado MCAM; Bomfim MRQ; Calixto JB -
Palladium based nanoparticles for the treatment of advanced melanoma.
Sci Rep Volume: 9 Page(s): 3255
03/01/2019 Authors: Elsey J; Bubley JA; Zhu L; Rao S; Sasaki M; Pollack BP; Yang L; Arbiser JL -
Exploiting Honokiol-induced ER stress CHOP activation inhibits the growth and metastasis of melanoma by suppressing the MITF and -catenin pathways.
Cancer Lett Volume: 442 Page(s): 113 - 125
02/01/2019 Authors: Chiu C-S; Tsai C-H; Hsieh M-S; Tsai S-C; Jan Y-J; Lin W-Y; Lai D-W; Wu S-M; Hsing H-Y; Arbiser JL -
Propranolol exhibits activity against hemangiomas independent of beta blockade.
NPJ Precis Oncol Volume: 3 Page(s): 27
01/01/2019 Authors: Sasaki M; North PE; Elsey J; Bubley J; Rao S; Jung Y; Wu S; Zou M-H; Pollack BP; Kumar J -
Chemoprevention agents for melanoma: A path forward into phase 3 clinical trials.
Cancer Volume: 125 Page(s): 18 - 44
01/01/2019 Authors: Jeter JM; Bowles TL; Curiel-Lewandrowski C; Swetter SM; Filipp FV; Abdel-Malek ZA; Geskin LJ; Brewer JD; Arbiser JL; Gershenwald JE -
Myofibroblast proliferation and heterogeneity are supported by macrophages during skin repair.
Science Volume: 362
11/23/2018 Authors: Shook BA; Wasko RR; Rivera-Gonzalez GC; Salazar-Gatzimas E; Lpez-Girldez F; Dash BC; Muoz-Rojas AR; Aultman KD; Zwick RK; Lei V -
Selenium unmasks protective iron armor: A possible defense against cutaneous inflammation and cancer.
Biochim Biophys Acta Gen Subj Volume: 1862 Page(s): 2518 - 2527
11/01/2018 Authors: Arbiser JL; Bonner MY; Ward N; Elsey J; Rao S -
Antioxidants: Positive or Negative Actors?
Biomolecules Volume: 8
10/25/2018 Authors: Salehi B; Martorell M; Arbiser JL; Sureda A; Martins N; Maurya PK; Sharifi-Rad M; Kumar P; Sharifi-Rad J -
ROS modifiers and NOX4 affect the expression of the survivin-associated radio-adaptive response.
Free Radic Biol Med Volume: 123 Page(s): 39 - 52
08/01/2018 Authors: Murley JS; Arbiser JL; Weichselbaum RR; Grdina DJ -
Honokiol Increases CD4+ T Cell Activation and Decreases TNF but Fails to Improve Survival Following Sepsis.
Shock Volume: 50 Page(s): 178 - 186
08/01/2018 Authors: Klingensmith NJ; Chen C-W; Liang Z; Burd EM; Farris AB; Arbiser JL; Ford ML; Coopersmith CM -
Salivary levels of angiopoietin-2 in infants with infantile haemangiomas treated with and without systemic propranolol.
Exp Dermatol Volume: 27 Page(s): 636 - 640
06/01/2018 Authors: Seamens A; Nieman E; Losavio K; Bradley B; Nelson K; Chen K-H; Chen S; Arbiser J; Lawley LP -
Palladium based nanoparticles for the treatment of advanced melanoma
Volume: 138 Page(s): S206 - S206
05/01/2018 Authors: Rao S; Sasaki M; Elsey J; Zhu L; Yang L; Arbiser J -
Targeting the Plasticity of Psoriasis.
J Invest Dermatol Volume: 138 Page(s): 734 - 736
04/01/2018 Authors: Arbiser JL; Elsey J -
Diablo: A Double-Edged Sword inCancer?
Mol Ther Volume: 26 Page(s): 678 - 679
03/07/2018 Authors: Arbiser JL -
Honokiol Radiosensitizes Squamous Cell Carcinoma of the Head and Neck by Downregulation of Survivin.
Clin Cancer Res Volume: 24 Page(s): 858 - 869
02/15/2018 Authors: Wang X; Beitler JJ; Huang W; Chen G; Qian G; Magliocca K; Patel MR; Chen AY; Zhang J; Nannapaneni S -
Targeting replication stress in triple negative breast cancer treatment regimen: An emerging approach
Volume: 78
02/01/2018 Authors: Rajamanickam S; Park JH; Bates K; Timilsina S; Eedunuri VK; Onyeagucha B; Subbarayalu P; Abdelfattah N; Jung KH; Favours E -
Honokiol is a FOXM1 antagonist.
Cell Death Dis Volume: 9 Page(s): 84
01/24/2018 Authors: Halasi M; Hitchinson B; Shah BN; Vraljai R; Khan I; Benevolenskaya EV; Gaponenko V; Arbiser JL; Gartel AL -
Regression of diffuse B-cell lymphoma of the leg with intralesional gentian violet
EXPERIMENTAL DERMATOLOGY Volume: 27 Page(s): 93 - 95
01/01/2018 Authors: Rao S; Morris R; Rice ZP; Arbiser JL -
Overcoming Resistance to Cetuximab with Honokiol, A Small-Molecule Polyphenol.
Mol Cancer Ther Volume: 17 Page(s): 204 - 214
01/01/2018 Authors: Pearson HE; Iida M; Orbuch RA; McDaniel NK; Nickel KP; Kimple RJ; Arbiser JL; Wheeler DL -
Regression of diffuse B-cell lymphoma of the leg with intralesional gentian violet.
Volume: 27 Page(s): 93 - 95
01/01/2018 Authors: Rao S; Morris R; Rice ZP; Arbiser JL -
Peroxisome proliferator-activated receptor gamma (PPAR) is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic target.
EMBO Mol Med Volume: 9 Page(s): 1763
12/01/2017 Authors: Pleniceanu O; Shukrun R; Omer D; Vax E; Kanter I; Dziedzic K; Pode-Shakked N; Mark-Daniei M; Pri-Chen S; Gnatek Y -
Activation of tumor suppressor LKB1 by honokiol abrogates cancer stem-like phenotype in breast cancer via inhibition of oncogenic Stat3.
Oncogene Volume: 36 Page(s): 5709 - 5721
10/12/2017 Authors: Sengupta S; Nagalingam A; Muniraj N; Bonner MY; Mistriotis P; Afthinos A; Kuppusamy P; Lanoue D; Cho S; Korangath P -
Treatment of Hailey-Hailey Disease With Low-Dose Naltrexone.
JAMA Dermatol Volume: 153 Page(s): 1018 - 1020
10/01/2017 Authors: Albers LN; Arbiser JL; Feldman RJ -
Evidence for biochemical barrier restoration: Topical solenopsin analogs improve inflammation and acanthosis in the KC-Tie2 mouse model of psoriasis.
Sci Rep Volume: 7 Page(s): 11198
09/11/2017 Authors: Arbiser JL; Nowak R; Michaels K; Skabytska Y; Biedermann T; Lewis MJ; Bonner MY; Rao S; Gilbert LC; Yusuf N -
Activation of Protein Kinase C in Merkel Cell Polyomavirus-Induced Merkel Cell Carcinoma.
JAMA Dermatol Volume: 153 Page(s): 931 - 932
09/01/2017 Authors: Costa A; Mackelfresh J; Gilbert L; Bonner MY; Arbiser JL -
Promoting intolerance: learning from warts.
Br J Dermatol Volume: 177 Page(s): 621 - 622
09/01/2017 Authors: Rao S; Arbiser JL -
Comprehensive profiling of H-Ras signalling in angiosarcoma endothelium.
Clin Exp Dermatol Volume: 42 Page(s): 645 - 647
08/01/2017 Authors: da Costa A; Bonner M; Arbiser JL -
Disruption of mitochondrial electron transport chain function potentiates the pro-apoptotic effects of MAPK inhibition.
J Biol Chem Volume: 292 Page(s): 11727 - 11739
07/14/2017 Authors: Trotta AP; Gelles JD; Serasinghe MN; Loi P; Arbiser JL; Chipuk JE -
Honokiol protects skin cells against inflammation, collagenolysis, apoptosis, and senescence caused by cigarette smoke damage.
Int J Dermatol Volume: 56 Page(s): 754 - 761
07/01/2017 Authors: Costa A; Facchini G; Pinheiro ALTA; da Silva MS; Bonner MY; Arbiser J; Eberlin S -
Imipramine blue sensitively and selectively targets FLT3-ITD positive acute myeloid leukemia cells.
Sci Rep Volume: 7 Page(s): 4447
06/30/2017 Authors: Metts J; Bradley HL; Wang Z; Shah NP; Kapur R; Arbiser JL; Bunting KD -
HMG-CoA synthase 1 is a synthetic lethal partner of BRAFV600E in human cancers.
J Biol Chem Volume: 292 Page(s): 10142 - 10152
06/16/2017 Authors: Zhao L; Fan J; Xia S; Pan Y; Liu S; Qian G; Qian Z; Kang H-B; Arbiser JL; Pollack BP -
HONOKIOL TREATMENT INCREASES DENDRITIC CELLS AND ACTIVATED CD4+T CELLS IN MURINE POLYMICROBIAL SEPSIS
Volume: 47 Page(s): 63 - 63
06/01/2017 Authors: Liang Z; Klingensmith N; Chen C-W; Burd E; Farris A; Arbiser J; Ford M; Coopersmith C -
Honokiol, an activator of Sirtuin-3 (SIRT3) preserves mitochondria and protects the heart from doxorubicin-induced cardiomyopathy in mice.
Oncotarget Volume: 8 Page(s): 34082 - 34098
05/23/2017 Authors: Pillai VB; Kanwal A; Fang YH; Sharp WW; Samant S; Arbiser J; Gupta MP -
Treatment of extensive erythema multiforme with topical gentian violet.
Exp Dermatol Volume: 26 Page(s): 431 - 432
05/01/2017 Authors: Murthy RK; Van L; Arbiser JL -
Blockade of hippo pathway effector YAP1 with shRNA attenuates vascular development in Hemangioma Bend3 cells in vivo
Volume: 137 Page(s): S18 - S18
05/01/2017 Authors: Bonner M; Pankove R; Rao S; Costa A; Shetata B; Elsey J; Arbiser JL -
Peroxisome proliferator-activated receptor gamma (PPAR) is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic target.
EMBO Mol Med Volume: 9 Page(s): 508 - 530
04/01/2017 Authors: Pleniceanu O; Shukrun R; Omer D; Vax E; Kanter I; Dziedzic K; Pode-Shakked N; Mark-Daniei M; Pri-Chen S; Gnatek Y -
Erratum to: Honokiol activates AMP-activated protein kinase in breast cancer cells via LKB1-dependent pathway and inhibits breast carcinogenesis.
Breast Cancer Res Volume: 19 Page(s): 39
03/28/2017 Authors: Nagalingam A; Arbiser JL; Bonner MY; Saxena NK; Sharma D -
Prevention of Dietary-Fat-Fueled Ketogenesis Attenuates BRAF V600E Tumor Growth.
Cell Metab Volume: 25 Page(s): 358 - 373
02/07/2017 Authors: Xia S; Lin R; Jin L; Zhao L; Kang H-B; Pan Y; Liu S; Qian G; Qian Z; Konstantakou E -
Double Jeopardy: The Rubber Ball Bounces Twice.
J Invest Dermatol Volume: 137 Page(s): 15 - 17
01/01/2017 Authors: Arbiser JL; Gilbert LC -
Targeting the duality of cancer.
NPJ Precis Oncol Volume: 1
01/01/2017 Authors: Arbiser JL; Bonner MY; Gilbert LC -
Factors Influencing Prescription Drug Costs in the United States.
JAMA Volume: 316 Page(s): 2430 - 2431
12/13/2016 Authors: Arbiser JL -
SIRT3 is attenuated in systemic sclerosis skin and lungs, and its pharmacologic activation mitigates organ fibrosis.
Oncotarget Volume: 7 Page(s): 69321 - 69336
10/25/2016 Authors: Akamata K; Wei J; Bhattacharyya M; Cheresh P; Bonner MY; Arbiser JL; Raparia K; Gupta MP; Kamp DW; Varga J -
Improvement of "En Coup de Sabre" Morphea and Associated Headaches With Botulinum Toxin Injections.
Dermatol Surg Volume: 42 Page(s): 1216 - 1219
10/01/2016 Authors: Rimoin L; Arbiser J -
Tris (dibenzylideneacetone) dipalladium: a small-molecule palladium complex is effective in inducing apoptosis in chronic lymphocytic leukemia B-cells.
Leuk Lymphoma Volume: 57 Page(s): 2409 - 2416
10/01/2016 Authors: Kay NE; Sassoon T; Secreto C; Sinha S; Shanafelt TD; Ghosh AK; Arbiser JL -
Down-Regulation of SOX2 Underlies the Inhibitory Effects of the Triphenylmethane Gentian Violet on Melanoma Cell Self-Renewal and Survival.
J Invest Dermatol Volume: 136 Page(s): 2059 - 2069
10/01/2016 Authors: Pietrobono S; Morandi A; Gagliardi S; Gerlini G; Borgognoni L; Chiarugi P; Arbiser JL; Stecca B -
Cooperation of imipramine blue and tyrosine kinase blockade demonstrates activity against chronic myeloid leukemia.
Oncotarget Volume: 7 Page(s): 51651 - 51664
08/09/2016 Authors: Laidlaw KME; Berhan S; Liu S; Silvestri G; Holyoake TL; Frank DA; Aggarwal B; Bonner MY; Perrotti D; Jrgensen HG -
Tris DBA palladium is highly effective against growth and metastasis of pancreatic cancer in an orthotopic model.
Oncotarget Volume: 7 Page(s): 51569 - 51580
08/09/2016 Authors: Daz B; Ostapoff KT; Toombs JE; Lo J; Bonner MY; Curatolo A; Adsay V; Brekken RA; Arbiser JL -
Use of Polyphenolic Compounds in Dermatologic Oncology.
Am J Clin Dermatol Volume: 17 Page(s): 369 - 385
08/01/2016 Authors: Costa A; Bonner MY; Arbiser JL -
Pro-Apoptotic Activity of New Honokiol/Triphenylmethane Analogues in B-Cell Lymphoid Malignancies.
Molecules Volume: 21
07/30/2016 Authors: Mdra A; Witkowska M; Majchrzak A; Cebula-Obrzut B; Bonner MY; Robak T; Arbiser JL; Smolewski P -
Inhibition of FoxM1-Mediated DNA Repair by Imipramine Blue Suppresses Breast Cancer Growth and Metastasis.
Clin Cancer Res Volume: 22 Page(s): 3524 - 3536
07/15/2016 Authors: Rajamanickam S; Panneerdoss S; Gorthi A; Timilsina S; Onyeagucha B; Kovalskyy D; Ivanov D; Hanes MA; Vadlamudi RK; Chen Y -
Tris DBA palladium overcomes hypoxia-mediated drug resistance in multiple myeloma.
Leuk Lymphoma Volume: 57 Page(s): 1677 - 1686
07/01/2016 Authors: de la Puente P; Azab F; Muz B; Luderer M; Arbiser J; Azab AK -
Enhanced Clearance of Pseudomonas aeruginosa by Peroxisome Proliferator-Activated Receptor Gamma.
Infect Immun Volume: 84 Page(s): 1975 - 1985
07/01/2016 Authors: Bedi B; Yuan Z; Joo M; Zughaier SM; Goldberg JB; Arbiser JL; Hart CM; Sadikot RT -
Effective local anesthesia for onabotulinumtoxin A injections to treat hyperhidrosis associated with traumatic amputation.
Dermatol Online J Volume: 22
06/15/2016 Authors: Shi LL; Sargen MR; Chen SC; Arbiser JL; Pollack BP -
Tuberculosis verrucosa cutis lesions exhibit a greater microvessel count than lupus vulgaris lesions.
Exp Dermatol Volume: 25 Page(s): 479 - 480
06/01/2016 Authors: Bhandarkar SS; Lanka P; Lanka LR; Veledar E; Bonner MY; MacKelfresh J; Arbiser JL -
Imipramine blue halts head and neck cancer invasion through promoting F-box and leucine-rich repeat protein 14-mediated Twist1 degradation.
Oncogene Volume: 35 Page(s): 2287 - 2298
05/05/2016 Authors: Yang W-H; Su Y-H; Hsu W-H; Wang C-C; Arbiser JL; Yang M-H -
Honokiol protects against cigarette smoke-induced collagen downregulation
Volume: 74 Page(s): AB27 - AB27
05/01/2016 Authors: Costa A; Clerici SP; Facchini G; Pinheiro A; Bonner MY; Arbiser J; Eberlin S -
A novel system to study the signaling of oncogene-induced senescence
Volume: 136 Page(s): S19 - S19
05/01/2016 Authors: da Costa A; Govindarajan B; Bonner MY; Rao S; Arbiser J -
Honokiol bis-dichloroacetate (Honokiol DCA) demonstrates activity in vemurafenib-resistant melanoma in vivo.
Volume: 7 Page(s): 12857 - 12868
03/15/2016 Authors: Bonner MY; Karlsson I; Rodolfo M; Arnold RS; Vergani E; Arbiser JL -
Seborrheic Keratoses: The Rodney Dangerfield of Skin lesions, and Why They Should Get Our Respect.
J Invest Dermatol Volume: 136 Page(s): 564 - 566
03/01/2016 Authors: Arbiser JL; Bonner MY -
Imipramine Blue - A safe and potent therapeutic regimen that suppresses breast cancer growth and progression by targeting DNA damage surveillance pathway
Volume: 76
02/15/2016 Authors: Rajamanickam S; Subbarayalu P; Timilsina S; Gorthi A; Drake MT; Chen Y; Vadlamudi R; Bishop AJR; Arbiser JL; Rao MK -
Imipramine Blue - A safe and potent therapeutic regimen that suppresses breast cancer growth and progression by targeting DNA damage surveillance pathway
Volume: 76
02/15/2016 Authors: Rajamanickam S; Subbarayalu P; Timilsina S; Gorthi A; Drake MT; Chen Y; Vadlamudi R; Bishop AJR; Arbiser JL; Rao MK -
Localized delivery of a lipophilic proteasome inhibitor into human skin for treatment of psoriasis.
J Drug Target Volume: 24 Page(s): 503 - 507
01/01/2016 Authors: Gujjar M; Arbiser J; Coulon R; Banga AK -
Gentian Violet: Bench-to-Bedside Research That Lowers Healthcare Costs.
Skinmed Volume: 14 Page(s): 91 - 92
01/01/2016 Authors: Arbiser JL -
Imipramine Blue Sensitively and Selectively Targets FLT3 and c-Kit Mutant Acute Myeloid Leukemia
Volume: 126
12/03/2015 Authors: Metts JL; Bradley HL; Shah NP; Kapur R; Arbiser JL; Bunting KD -
Designing a broad-spectrum integrative approach for cancer prevention and treatment.
Semin Cancer Biol Volume: 35 Suppl Page(s): S276 - S304
12/01/2015 Authors: Block KI; Gyllenhaal C; Lowe L; Amedei A; Amin ARMR; Amin A; Aquilano K; Arbiser J; Arreola A; Arzumanyan A -
Evasion of anti-growth signaling: A key step in tumorigenesis and potential target for treatment and prophylaxis by natural compounds.
Semin Cancer Biol Volume: 35 Suppl Page(s): S55 - S77
12/01/2015 Authors: Amin ARMR; Karpowicz PA; Carey TE; Arbiser J; Nahta R; Chen ZG; Dong J-T; Kucuk O; Khan GN; Huang GS -
Honokiol activates LKB1-miR-34a axis and antagonizes the oncogenic actions of leptin in breast cancer.
Oncotarget Volume: 6 Page(s): 29947 - 29962
10/06/2015 Authors: Avtanski DB; Nagalingam A; Bonner MY; Arbiser JL; Saxena NK; Sharma D -
Metabolic Rewiring by Oncogenic BRAF V600E Links Ketogenesis Pathway to BRAF-MEK1 Signaling.
Mol Cell Volume: 59 Page(s): 345 - 358
08/06/2015 Authors: Kang H-B; Fan J; Lin R; Elf S; Ji Q; Zhao L; Jin L; Seo JH; Shan C; Arbiser JL -
Honokiol radiosensitizes squamous cells carcinoma of head and neck by down-regulation of survivin
Volume: 75
08/01/2015 Authors: Wang X; Beitler JJ; Huang W; Qian G; Magliocca K; Zhang J; Nannapaneni S; Kim S; Chen Z; Nabil SF -
Imipramine blue: a novel NOX inhibitor as potent therapeutic agent to treat triple-negative breast cancers
Volume: 75
08/01/2015 Authors: Rajamanickam S; Subbarayalu P; Timilsina S; Drake MT; Zhao Z; Chen HIH; Chen Y; Arbiser JL; Rao MKK -
Efficacy of Rapamycin in Tuberous Sclerosis-Associated Hypopigmented Macules: Back to the Future.
JAMA Dermatol Volume: 151 Page(s): 703 - 704
07/01/2015 Authors: Arbiser JL -
Honokiol abrogates leptin-induced tumor progression by inhibiting Wnt1-MTA1--catenin signaling axis in a microRNA-34a dependent manner.
Oncotarget Volume: 6 Page(s): 16396 - 16410
06/30/2015 Authors: Avtanski DB; Nagalingam A; Kuppusamy P; Bonner MY; Arbiser JL; Saxena NK; Sharma D -
A tale of two macrophages: to Shb or not to Shb.
Acta Physiol (Oxf) Volume: 214 Page(s): 152 - 153
06/01/2015 Authors: Arbiser JL -
In vitro skin irritation and potential efficacy of a novel compound for localized treatment of psoriasis
Volume: 135 Page(s): S11 - S11
05/01/2015 Authors: Gujjar M; Arbiser JL; Coulon R; Banga AK -
Angiogenesis in lupus vulgaris and tuberculosis verrucosa cutis lesions of cutaneous tuberculosis
Volume: 135 Page(s): S31 - S31
05/01/2015 Authors: Bhandarkar S; Lanka P; Lanka LR; Bonner M; Mackelfresh J; Arbiser JL -
Topical solenopsin analogs improve inflammation and acanthosis in the KC-Tie2 mouse model of psoriasis
Volume: 135 Page(s): S85 - S85
05/01/2015 Authors: Arbiser JL; Michaels KA; Nowak RS; Bonner M; Karlsson I; Fritz Y; Ward NL -
Honokiol blocks and reverses cardiac hypertrophy in mice by activating mitochondrial Sirt3.
Nat Commun Volume: 6 Page(s): 6656
04/14/2015 Authors: Pillai VB; Samant S; Sundaresan NR; Raghuraman H; Kim G; Bonner MY; Arbiser JL; Walker DI; Jones DP; Gius D -
Inactivation of NADPH oxidases NOX4 and NOX5 protects human primary fibroblasts from ionizing radiation-induced DNA damage.
Radiat Res Volume: 183 Page(s): 262 - 270
03/01/2015 Authors: Weyemi U; Redon CE; Aziz T; Choudhuri R; Maeda D; Parekh PR; Bonner MY; Arbiser JL; Bonner WM -
NADPH oxidase 4 is a critical mediator in Ataxia telangiectasia disease.
Proc Natl Acad Sci U S A Volume: 112 Page(s): 2121 - 2126
02/17/2015 Authors: Weyemi U; Redon CE; Aziz T; Choudhuri R; Maeda D; Parekh PR; Bonner MY; Arbiser JL; Bonner WM -
Solenopsin A and analogs exhibit ceramide-like biological activity.
Vasc Cell Volume: 7 Page(s): 5
01/01/2015 Authors: Karlsson I; Zhou X; Thomas R; Smith AT; Bonner MY; Bakshi P; Banga AK; Bowen JP; Qabaja G; Ford SL -
Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells.
Microvasc Res Volume: 97 Page(s): 55 - 64
01/01/2015 Authors: Mochin MT; Underwood KF; Cooper B; McLenithan JC; Pierce AD; Nalvarte C; Arbiser J; Karlsson AI; Moise AR; Moskovitz J -
Novel mechanistic insights into the bioactive compound honokiol-mediated inhibition of epithelial to mesenchymal transition in breast cancer: Therapeutic modulation of miR-34a via tumor suppressor LKB1
Volume: 74
10/01/2014 Authors: Avtanski DB; Bonner MY; Tiutan TP; Arbiser JL; Saxena NK; Sharma D -
Inhibiting "Dedifferentiation" in breast cancer cells using Honokiol - a plant derived polyphenol
Volume: 74
10/01/2014 Authors: Sengupta S; Bonner MY; Arbiser JL; Saxena NK; Sharma D -
The novel Aryl hydrocarbon receptor inhibitor biseugenol inhibits gastric tumor growth and peritoneal dissemination.
Oncotarget Volume: 5 Page(s): 7788 - 7804
09/15/2014 Authors: Lai D-W; Liu S-H; Karlsson AI; Lee W-J; Wang K-B; Chen Y-C; Shen C-C; Wu S-M; Liu C-Y; Tien H-R -
Honokiol inhibits epithelial-mesenchymal transition in breast cancer cells by targeting signal transducer and activator of transcription 3/Zeb1/E-cadherin axis.
Mol Oncol Volume: 8 Page(s): 565 - 580
05/01/2014 Authors: Avtanski DB; Nagalingam A; Bonner MY; Arbiser JL; Saxena NK; Sharma D -
Current approaches to the treatment of metastatic brain tumours.
Nat Rev Clin Oncol Volume: 11 Page(s): 203 - 222
04/01/2014 Authors: Owonikoko TK; Arbiser J; Zelnak A; Shu H-KG; Shim H; Robin AM; Kalkanis SN; Whitsett TG; Salhia B; Tran NL -
Gentian violet induces wtp53 transactivation in cancer cells.
Int J Oncol Volume: 44 Page(s): 1084 - 1090
04/01/2014 Authors: Garufi A; D'Orazi V; Arbiser JL; D'Orazi G -
Honokiol inhibits androgen receptor activity in prostate cancer cells.
Prostate Volume: 74 Page(s): 408 - 420
04/01/2014 Authors: Hahm E-R; Karlsson AI; Bonner MY; Arbiser JL; Singh SV -
PHIPing out: a genetic basis for tumor ulceration.
J Invest Dermatol Volume: 134 Page(s): 600 - 602
03/01/2014 Authors: Arbiser JL -
Honokiol enhances paclitaxel efficacy in multi-drug resistant human cancer model through the induction of apoptosis.
PLoS One Volume: 9 Page(s): e86369
01/01/2014 Authors: Wang X; Beitler JJ; Wang H; Lee MJ; Huang W; Koenig L; Nannapaneni S; Amin ARMR; Bonner M; Shin HJC -
Suppression of NF-B activation by gentian violet promotes osteoblastogenesis and suppresses osteoclastogenesis.
Curr Mol Med Volume: 14 Page(s): 783 - 792
01/01/2014 Authors: Yamaguchi M; Vikulina T; Arbiser JL; Weitzmann MN -
The antioxidant paradox: what are antioxidants and how should they be used in a therapeutic context for cancer.
Future Med Chem Volume: 6 Page(s): 1413 - 1422
01/01/2014 Authors: Bonner MY; Arbiser JL -
Gentian violet: a 19th century drug re-emerges in the 21st century.
Exp Dermatol Volume: 22 Page(s): 775 - 780
12/01/2013 Authors: Maley AM; Arbiser JL -
The natural product honokiol inhibits calcineurin inhibitor-induced and Ras-mediated tumor promoting pathways.
Cancer Lett Volume: 338 Page(s): 292 - 299
09/28/2013 Authors: Banerjee P; Basu A; Arbiser JL; Pal S -
Reductions in funding for medical research.
JAMA Volume: 310 Page(s): 855 - 856
08/28/2013 Authors: Arbiser JL -
In vivo Gram staining of tinea versicolor.
JAMA Dermatol Volume: 149 Page(s): 991 - 992
08/01/2013 Authors: Spence-Shishido A; Carr C; Bonner MY; Arbiser JL -
Inducing apoptosis of cancer cells using small-molecule plant compounds that bind to GRP78.
Br J Cancer Volume: 109 Page(s): 433 - 443
07/23/2013 Authors: Martin S; Lamb HK; Brady C; Lefkove B; Bonner MY; Thompson P; Lovat PE; Arbiser JL; Hawkins AR; Redfern CPF -
Identifying new small molecule anti-invasive compounds for glioma treatment.
Cell Cycle Volume: 12 Page(s): 2200 - 2209
07/15/2013 Authors: Munson J; Bonner M; Fried L; Hofmekler J; Arbiser J; Bellamkonda R -
Novel synthesis and sctivity of solenopsin A and analogs, topical inhibitors of phosphoinositol-3 kinase/akt with ceramide-like properties
Volume: 133 Page(s): S252 - S252
05/01/2013 Authors: Karlsson I; Bonner MY; Zhou X; Zhang J; Watkins EB; Bowen JP; Arbiser JL -
COMBINATION OF ANTIANGIOGENIC AGENTS FOR INHIBITING REGENERATION OF PHOTOCOAGULATED BLOOD VESSELS IN AN IN VIVO MICROVASCULAR MODEL
LASERS IN SURGERY AND MEDICINE Volume: 45 Page(s): 5 - 6
03/01/2013 Authors: Jia W; Sun V; Tan W; Choi B; Mihm MC; Arbiser J; Nelson JS -
DISCOVERY OF NOVEL FETAL HEMOGLOBIN INDUCING DRUGS TO TREAT SICKLE CELL DISEASE
Volume: 61 Page(s): 464 - 465
02/01/2013 Authors: Okonkwo A; Li B; Takezaki M; Arbiser JL; Pace BS -
Selectivity, binding affinity, and ionization state of matrix metalloproteinase inhibitors.
Curr Pharm Des Volume: 19 Page(s): 4701 - 4713
01/01/2013 Authors: Zhong HA; Arbiser J; Bowen JP -
Triphenylmethane derivatives have high in vitro and in vivo activity against the main causative agents of cutaneous leishmaniasis.
PLoS One Volume: 8 Page(s): e51864
01/01/2013 Authors: de Souza Pietra RCC; Rodrigues LF; Teixeira E; Fried L; Lefkove B; Rabello A; Arbiser J; Ferreira LAM; Fernandes AP -
Honokiol Blocks Cardiac Hypertrophic Response via Activation of SIRT3
CIRCULATION Volume: 126
11/20/2012 Authors: Pillai VB; Sundaresan NR; Kim G; Samant S; Arbiser J; Gupta MP -
Targeting Mitochondrial Antioxidant Networks in Mesothelioma
Volume: 53 Page(s): S43 - S44
11/01/2012 Authors: Heintz NH; Newick K; Cunniff B; Held P; Shukla A; Joseph J; Arbiser J; Kalyanaraman B -
Zebrafish lead the way in control of vascular permeability.
Blood Volume: 120 Page(s): 2162 - 2164
09/13/2012 Authors: Arbiser JL -
Targeting the intrinsic inflammatory pathway: honokiol exerts proapoptotic effects through STAT3 inhibition in transformed Barrett's cells.
Am J Physiol Gastrointest Liver Physiol Volume: 303 Page(s): G561 - G569
09/01/2012 Authors: Yu C; Zhang Q; Zhang HY; Zhang X; Huo X; Cheng E; Wang DH; Arbiser JL; Spechler SJ; Souza RF -
Combination therapy of imiquimod and gentian violet for cutaneous melanoma metastases.
J Am Acad Dermatol Volume: 67 Page(s): e81 - e83
08/01/2012 Authors: Arbiser JL; Bips M; Seidler A; Bonner MY; Kovach C -
Cooperative benefit for the combination of rapamycin and imatinib in tuberous sclerosis complex neoplasia.
Vasc Cell Volume: 4 Page(s): 11
07/05/2012 Authors: Govindarajan B; Willoughby L; Band H; Curatolo AS; Veledar E; Chen S; Bonner MY; Abel M-G; Moses MA; Arbiser JL -
Honokiol induces cell cycle arrest and apoptosis via inhibition of survival signals in adult T-cell leukemia.
Biochim Biophys Acta Volume: 1820 Page(s): 879 - 887
07/01/2012 Authors: Ishikawa C; Arbiser JL; Mori N -
Targeting NADPH oxidases for the treatment of cancer and inflammation.
Cell Mol Life Sci Volume: 69 Page(s): 2435 - 2442
07/01/2012 Authors: Bonner MY; Arbiser JL -
THE APPLICATION OF NANOPARTICLE LIPOSOME-IMPRAMINE BLUE IN THE TREATMENT OF MEDULLOBLASTOMA IN THE SmoA1 TRANSGENIC MICE
Volume: 14 Page(s): 83 - 83
06/01/2012 Authors: MacDonald T; Liu J; Munson J; Park J; Wang K; Fei B; Bellamkonda R; Arbiser J -
NHERF-2 silences the silencers.
Blood Volume: 119 Page(s): 4582 - 4584
05/17/2012 Authors: Arbiser JL -
Evidence for a napdh oxidase-stat5 pathway in human melanoma
Volume: 132 Page(s): S26 - S26
05/01/2012 Authors: Arbiser JL; Bonner MY; Cerulli R; Liu S; Frank DA -
Antimetastatic activity of honokiol in osteosarcoma.
Cancer Volume: 118 Page(s): 2117 - 2127
04/15/2012 Authors: Steinmann P; Walters DK; Arlt MJE; Banke IJ; Ziegler U; Langsam B; Arbiser J; Muff R; Born W; Fuchs B -
Honokiol reduces drug resistance by down-regulation of survivin expression in multidrug resistant squamous cell carcinoma of the head and neck
CANCER RESEARCH Volume: 72
04/15/2012 Authors: Wang X; Beitler JJ; Hong HW; Lee MJ; Chen Z; Koenig L; Amin ARR; Chen ZG; Arbiser JL; Shin DM -
Anti-invasive adjuvant therapy with imipramine blue enhances chemotherapeutic efficacy against glioma.
Sci Transl Med Volume: 4 Page(s): 127ra36
03/28/2012 Authors: Munson JM; Fried L; Rowson SA; Bonner MY; Karumbaiah L; Diaz B; Courtneidge SA; Knaus UG; Brat DJ; Arbiser JL -
Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the RG mouse model of tuberous sclerosis complex.
Neurobiol Dis Volume: 45 Page(s): 1101 - 1110
03/01/2012 Authors: Chvere-Torres I; Kaphzan H; Bhattacharya A; Kang A; Maki JM; Gambello MJ; Arbiser JL; Santini E; Klann E -
Honokiol activates AMP-activated protein kinase in breast cancer cells via an LKB1-dependent pathway and inhibits breast carcinogenesis.
Breast Cancer Res Volume: 14 Page(s): R35
02/21/2012 Authors: Nagalingam A; Arbiser JL; Bonner MY; Saxena NK; Sharma D -
Peroxiredoxin 3 is a redox-dependent target of thiostrepton in malignant mesothelioma cells.
PLoS One Volume: 7 Page(s): e39404
01/01/2012 Authors: Newick K; Cunniff B; Preston K; Held P; Arbiser J; Pass H; Mossman B; Shukla A; Heintz N -
Transgrediens pachyonychia congenita (PC): case series of a nonclassical PC presentation.
Br J Dermatol Volume: 166 Page(s): 124 - 128
01/01/2012 Authors: Harris K; Hull PR; Hansen CD; Smith FJD; McLean WHI; Arbiser JL; Leachman SA -
Forty-year journey of angiogenesis translational research.
Sci Transl Med Volume: 3 Page(s): 114rv3
12/21/2011 Authors: Cao Y; Arbiser J; D'Amato RJ; D'Amore PA; Ingber DE; Kerbel R; Klagsbrun M; Lim S; Moses MA; Zetter B -
Honokiol stimulates osteoblastogenesis by suppressing NF-B activation.
Int J Mol Med Volume: 28 Page(s): 1049 - 1053
12/01/2011 Authors: Yamaguchi M; Arbiser JL; Weitzmann MN -
Pro-Apoptotic Activity of Honokiol Analogues in B-Cell Lymphoid Malignancies
Volume: 118 Page(s): 723 - 723
11/18/2011 Authors: Smolewski P; Jeske A; Majchrzak A; Cebula B; Bonner MY; Arbiser JL; Robak T -
TRIS (DIBENZYLIDENEACETONE) Dipalladium a Small-Molecule Palladium Complex Is Effective in the Induction of Apoptosis for B-Chronic Lymphocytic Leukemia B-Cells
Volume: 118 Page(s): 1229 - 1230
11/18/2011 Authors: Kay N; Sassoon T; Secreto C; Ghosh AK; Arbiser JL -
Targeting Redox Homeostasis in Malignant Mesothelioma
Volume: 51 Page(s): S127 - S127
11/01/2011 Authors: Newick K; Cunniff B; Held P; Shukla A; Pass H; Butnor K; Kundu K; Murthy N; Mossman B; Arbiser J -
Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity.
Nat Med Volume: 17 Page(s): 1121 - 1127
08/28/2011 Authors: Diano S; Liu Z-W; Jeong JK; Dietrich MO; Ruan H-B; Kim E; Suyama S; Kelly K; Gyengesi E; Arbiser JL -
Beating the rap in angiogenesis.
Blood Volume: 118 Page(s): 1719 - 1720
08/18/2011 Authors: Arbiser JL -
A key role for NOX4 in epithelial cell death during development of lung fibrosis.
Antioxid Redox Signal Volume: 15 Page(s): 607 - 619
08/01/2011 Authors: Carnesecchi S; Deffert C; Donati Y; Basset O; Hinz B; Preynat-Seauve O; Guichard C; Arbiser JL; Banfi B; Pache J-C -
The impact of ionization States of matrix metalloproteinase inhibitors on docking-based inhibitor design.
ACS Med Chem Lett Volume: 2 Page(s): 455 - 460
06/09/2011 Authors: Zhong H; Wees MA; Faure TD; Carrillo C; Arbiser J; Bowen JP -
Fisetin: a natural fist against melanoma?
J Invest Dermatol Volume: 131 Page(s): 1187 - 1189
06/01/2011 Authors: Arbiser JL; Fisher DE -
Fumarate esters as angiogenesis inhibitors: key to action in psoriasis?
J Invest Dermatol Volume: 131 Page(s): 1189 - 1191
06/01/2011 Authors: Arbiser JL -
Novel antiangiogenic agents in dermatology.
Arch Biochem Biophys Volume: 508 Page(s): 222 - 226
04/15/2011 Authors: Berrios RL; Arbiser JL -
Targeting cell survival pathways with the combination of honokiol and resveratrol for prevention of head and neck cancer
CANCER RESEARCH Volume: 71
04/15/2011 Authors: Amin ARMR; Jung K-H; Wang D; Arbiser JL; Chen ZG; Shin DM -
Voriconazole treatment plus UVB irradiation causes malignant transformation of human HaCaT keratinocyes
Volume: 131 Page(s): S16 - S16
04/01/2011 Authors: Berrios RL; Martin-Garrido A; Bonner MY; Pollack BP; Arbiser JL -
Disruption of the mitochondrial thioredoxin system as a cell death mechanism of cationic triphenylmethanes.
Free Radic Biol Med Volume: 50 Page(s): 811 - 820
04/01/2011 Authors: Zhang X; Zheng Y; Fried LE; Du Y; Montano SJ; Sohn A; Lefkove B; Holmgren L; Arbiser JL; Holmgren A -
Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPAR mediated mechanism.
PLoS One Volume: 6 Page(s): e14665
02/07/2011 Authors: Garrido-Urbani S; Jemelin S; Deffert C; Carnesecchi S; Basset O; Szyndralewiez C; Heitz F; Page P; Montet X; Michalik L -
Transgrediens lesions in patients with pachyonychia congenita
Volume: 64 Page(s): AB84 - AB84
02/01/2011 Authors: Harris K; Hansen CD; Leachman S; McLean FSI; Arbiser J; Hull P -
High level expression of angiopoietin-2 in human abscesses.
J Am Acad Dermatol Volume: 64 Page(s): 200 - 201
01/01/2011 Authors: Bartus C; Brown LF; Bonner MY; Arbiser JL -
Effectiveness of gentian violet and similar products commonly used to treat pyodermas.
Dermatol Clin Volume: 29 Page(s): 69 - 73
01/01/2011 Authors: Berrios RL; Arbiser JL -
Molecular patterns in melanoma and therapeutic targets.
G Ital Dermatol Venereol Volume: 145 Page(s): 597 - 602
10/01/2010 Authors: Chua RA; Arbiser JL -
A nonsteroidal alternative to impetiginized eczema in the emergency room.
J Am Acad Dermatol Volume: 63 Page(s): 537 - 539
09/01/2010 Authors: Stoff B; MacKelfresh J; Fried L; Cohen C; Arbiser JL -
Enhanced MCP-1 release by keloid CD14+ cells augments fibroblast proliferation: role of MCP-1 and Akt pathway in keloids.
Exp Dermatol Volume: 19 Page(s): e142 - e150
08/01/2010 Authors: Liao W-T; Yu H-S; Arbiser JL; Hong C-H; Govindarajan B; Chai C-Y; Shan W-J; Lin Y-F; Chen G-S; Lee C-H -
EC-specific chemotaxis receptor: a double-edged sword.
Blood Volume: 115 Page(s): 4328 - 4329
06/03/2010 Authors: Arbiser JL -
Honokiol inhibits epidermal growth factor receptor signaling and enhances the antitumor effects of epidermal growth factor receptor inhibitors.
Clin Cancer Res Volume: 16 Page(s): 2571 - 2579
05/01/2010 Authors: Leeman-Neill RJ; Cai Q; Joyce SC; Thomas SM; Bhola NE; Neill DB; Arbiser JL; Grandis JR -
Novel nanoparticle-delivered compound, Imipramine Blue, halts glioma invasion by affecting actin dynamics
CANCER RESEARCH Volume: 70
04/01/2010 Authors: Munson JM; Bonner M; Karumbaiah L; Arbiser J; Bellamkonda R -
Rapid improvement of nephrogenic systemic fibrosis with rapamycin therapy: possible role of phospho-70-ribosomal-S6 kinase.
J Am Acad Dermatol Volume: 62 Page(s): 343 - 345
02/01/2010 Authors: Swaminathan S; Arbiser JL; Hiatt KM; High W; Abul-Ezz S; Horn TD; Shah SV -
Ulcerative granulomatous mycosis fungoides.
Skinmed Volume: 8 Page(s): 188 - 190
01/01/2010 Authors: Parker SRS; Traywick C; Arbiser JL -
Translating cyclooxygenase signaling in patch heterozygote mice into a randomized clinical trial in basal cell carcinoma.
Cancer Prev Res (Phila) Volume: 3 Page(s): 4 - 7
01/01/2010 Authors: Arbiser JL -
The role of angiogenesis in the pathogenesis of psoriasis.
Autoimmunity Volume: 42 Page(s): 574 - 579
11/01/2009 Authors: Chua RA; Arbiser JL -
Hemangiomas, angiosarcomas, and vascular malformations represent the signaling abnormalities of pathogenic angiogenesis.
Curr Mol Med Volume: 9 Page(s): 929 - 934
11/01/2009 Authors: Arbiser JL; Bonner MY; Berrios RL -
Disseminated pyoderma gangrenosum: role for vascular endothelial growth factor and hypoxia inducible factor-2.
J Am Acad Dermatol Volume: 61 Page(s): 730 - 732
10/01/2009 Authors: Chua RA; Mackelfresh J; Cohen C; Varma V; Fried L; Arbiser JL -
Tuberous sclerosis complex suppression in cerebellar development and medulloblastoma: separate regulation of mammalian target of rapamycin activity and p27 Kip1 localization.
Cancer Res Volume: 69 Page(s): 7224 - 7234
09/15/2009 Authors: Bhatia B; Northcott PA; Hambardzumyan D; Govindarajan B; Brat DJ; Arbiser JL; Holland EC; Taylor MD; Kenney AM -
Honokiol, a natural plant product from magnolia tree, inhibits the bone metastatic growth of human prostate cancer cells
Volume: 7 Page(s): 418 - 418
09/01/2009 Authors: Shigemura K; Chung LWK; Arbiser JL; Gotoh A; Yamashita M; Fujisawa M -
Gentian violet is safe.
J Am Acad Dermatol Volume: 61 Page(s): 359
08/01/2009 Authors: Arbiser JL -
Fulvene-5 potently inhibits NADPH oxidase 4 and blocks the growth of endothelial tumors in mice.
J Clin Invest Volume: 119 Page(s): 2359 - 2365
08/01/2009 Authors: Bhandarkar SS; Jaconi M; Fried LE; Bonner MY; Lefkove B; Govindarajan B; Perry BN; Parhar R; Mackelfresh J; Sohn A -
Secreted frizzle-related protein 2 stimulates angiogenesis via a calcineurin/NFAT signaling pathway.
Cancer Res Volume: 69 Page(s): 4621 - 4628
06/01/2009 Authors: Courtwright A; Siamakpour-Reihani S; Arbiser JL; Banet N; Hilliard E; Fried L; Livasy C; Ketelsen D; Nepal DB; Perou CM -
Melanomas reveal their nakedness: uncovered by interferon alfa.
Arch Dermatol Volume: 145 Page(s): 587 - 588
05/01/2009 Authors: Arbiser JL; Bonner MY -
Maspin expression, angiogenesis, prognostic parameters, and outcome in malignant melanoma.
J Am Acad Dermatol Volume: 60 Page(s): 758 - 766
05/01/2009 Authors: Chua R; Setzer S; Govindarajan B; Sexton D; Cohen C; Arbiser JL -
Honokiol, a multifunctional antiangiogenic and antitumor agent.
Antioxid Redox Signal Volume: 11 Page(s): 1139 - 1148
05/01/2009 Authors: Fried LE; Arbiser JL -
Carbazole modulates chemokine production by the transformed human microvascular endothelial cell line HMEC-1 and antigen presentation by murine epidermal cells
Volume: 129 Page(s): S16 - S16
04/01/2009 Authors: Culjis C; Huang J; Arbiser J; Ding W; Granstein R -
Unexpected autocrine role of vascular endothelial growth factor in squamous cell carcinoma.
J Invest Dermatol Volume: 129 Page(s): 538 - 540
03/01/2009 Authors: Arbiser JL -
Efficacy of topical application of eosin for ulcerated hemangiomas.
J Am Acad Dermatol Volume: 60 Page(s): 350 - 351
02/01/2009 Authors: Lapidoth M; Ben-Amitai D; Bhandarkar S; Fried L; Arbiser JL -
Tacrolimus Inhibits the Growth of Angiosarcoma in Mice
ANNALS OF SURGICAL ONCOLOGY Volume: 16 Page(s): 19 - 19
02/01/2009 Authors: Klauber-DeMore N; Arbiser JL; Livasy C; Ketelsen D; Hilliard E; Fried L; Siamakpour-Reihani S; Perou C; Patterson C -
Imipramine Blue, a Tricyclic Compound and an Inhibitor of NADPH Oxidase Induces G(2)/M Cell-Cycle Arrest
CLINICAL LYMPHOMA & MYELOMA Volume: 9 Page(s): S126 - S126
02/01/2009 Authors: David E; Lonial S; Kaufman JL; Arbiser J -
The hunting of the Snrk.
Blood Volume: 113 Page(s): 983 - 984
01/29/2009 Authors: Arbiser JL; Fried L -
Honokiol-mediated inhibition of PI3K/mTOR pathway: a potential strategy to overcome immunoresistance in glioma, breast, and prostate carcinoma without impacting T cell function.
J Immunother Volume: 32 Page(s): 585 - 592
01/01/2009 Authors: Crane C; Panner A; Pieper RO; Arbiser J; Parsa AT -
Redox Regulation of FoxM1 in Malignant Mesothelioma cells
Volume: 47 Page(s): S173 - S173
01/01/2009 Authors: Heintz NH; Newick K; Mossman BT; Hillegass J; Beuschel S; Shukla A; Arbiser J; Pass H -
Immunosuppression may be present within condyloma acuminata.
J Am Acad Dermatol Volume: 59 Page(s): 967 - 974
12/01/2008 Authors: Le Poole C; Denman CJ; Arbiser JL -
Prox-1 promotes invasion of kaposiform hemangioendotheliomas.
J Invest Dermatol Volume: 128 Page(s): 2798 - 2806
12/01/2008 Authors: Dadras SS; Skrzypek A; Nguyen L; Shin JW; Schulz MMP; Arbiser J; Mihm MC; Detmar M -
Solenopsin A, a venom alkaloid from the fire ant Solenopsis invicta, inhibits quorum-sensing signaling in Pseudomonas aeruginosa.
J Infect Dis Volume: 198 Page(s): 1198 - 1201
10/15/2008 Authors: Park J; Kaufmann GF; Bowen JP; Arbiser JL; Janda KD -
T CELL EFFECTOR FUNCTIONS FOLLOWING TREATMENT WITH PI(3) KINASE INHIBITORS
Volume: 10 Page(s): 815 - 815
10/01/2008 Authors: Crane C; Panner A; Murray J; Cachola K; Pieper R; Arbiser J; Parsa A -
EFFECTS OF TSC2 INACTIVATION ON CEREBELLAR DEVELOPMENT AND MEDULLOBLASTOMA
Volume: 10 Page(s): 869 - 869
10/01/2008 Authors: Bhatia B; Thiruvenkatam R; Arbiser J; Gilbertson R; Kenney A -
Tris (dibenzylideneacetone) dipalladium, a N-myristoyltransferase-1 inhibitor, is effective against melanoma growth in vitro and in vivo.
Clin Cancer Res Volume: 14 Page(s): 5743 - 5748
09/15/2008 Authors: Bhandarkar SS; Bromberg J; Carrillo C; Selvakumar P; Sharma RK; Perry BN; Govindarajan B; Fried L; Sohn A; Reddy K -
Honokiol is a potent scavenger of superoxide and peroxyl radicals.
Biochem Pharmacol Volume: 76 Page(s): 589 - 596
09/01/2008 Authors: Dikalov S; Losik T; Arbiser JL -
Epidermal vascular endothelial growth factor production is required for permeability barrier homeostasis, dermal angiogenesis, and the development of epidermal hyperplasia: implications for the pathogenesis of psoriasis.
Am J Pathol Volume: 173 Page(s): 689 - 699
09/01/2008 Authors: Elias PM; Arbiser J; Brown BE; Rossiter H; Man M-Q; Cerimele F; Crumrine D; Gunathilake R; Choi EH; Uchida Y -
The antidepressant sertraline downregulates Akt and has activity against melanoma cells.
Pigment Cell Melanoma Res Volume: 21 Page(s): 451 - 456
08/01/2008 Authors: Reddy KK; Lefkove B; Chen LB; Govindarajan B; Carracedo A; Velasco G; Carrillo CO; Bhandarkar SS; Owens MJ; Mechta-Grigoriou F -
A modified cysteinyl-labeling assay reveals reversible oxidation of protein tyrosine phosphatases in angiomyolipoma cells.
Proc Natl Acad Sci U S A Volume: 105 Page(s): 9959 - 9964
07/22/2008 Authors: Boivin B; Zhang S; Arbiser JL; Zhang Z-Y; Tonks NK -
The natural product honokiol preferentially inhibits cellular FLICE-inhibitory protein and augments death receptor-induced apoptosis.
Mol Cancer Ther Volume: 7 Page(s): 2212 - 2223
07/01/2008 Authors: Raja SM; Chen S; Yue P; Acker TM; Lefkove B; Arbiser JL; Khuri FR; Sun S-Y -
Honokiol suppresses survival signals mediated by Ras-dependent phospholipase D activity in human cancer cells.
Clin Cancer Res Volume: 14 Page(s): 4267 - 4274
07/01/2008 Authors: Garcia A; Zheng Y; Zhao C; Toschi A; Fan J; Shraibman N; Brown HA; Bar-Sagi D; Foster DA; Arbiser JL -
The reactive oxygen-driven tumor: relevance to melanoma.
Pigment Cell Melanoma Res Volume: 21 Page(s): 117 - 122
04/01/2008 Authors: Fried L; Arbiser JL -
Epidermal VEGF is required for permeability barrier homeostasis, dermal angiogenesis and development of epidermal hyperplasia: implications for the provocation of psoriasis
Volume: 128 Page(s): S1 - S1
04/01/2008 Authors: Elias PM; Arbiser J; Brown BE; Rossiter H; Man M; Cerimele F; Crumrine D; Gunathilake R; Choi E; Feingold KR -
Targeted therapy of oral hairy leukoplakia with gentian violet.
J Am Acad Dermatol Volume: 58 Page(s): 711 - 712
04/01/2008 Authors: Bhandarkar SS; MacKelfresh J; Fried L; Arbiser JL -
Shb gene knockdown increases the susceptibility of SVR endothelial tumor cells to apoptotic stimuli in vitro and in vivo.
J Invest Dermatol Volume: 128 Page(s): 710 - 716
03/01/2008 Authors: Funa NS; Reddy K; Bhandarkar S; Kurenova EV; Yang L; Cance WG; Welsh M; Arbiser JL -
Efficacy of rapamycin in scleroderma: a case study.
Lymphat Res Biol Volume: 6 Page(s): 217 - 219
01/01/2008 Authors: Fried L; Kirsner RS; Bhandarkar S; Arbiser JL -
Application of angiogenesis to clinical dermatology.
Adv Dermatol Volume: 24 Page(s): 89 - 103
01/01/2008 Authors: Fried LE; Arbiser JL -
PRL-3 protein expression in sinonasal and cutaneous melanoma
Volume: 21 Page(s): 97A - 97A
01/01/2008 Authors: Lim MG; Arbiser JB; Lamson D; Shou C; Chong XJ; Stein IM; Muller S; Cohen C -
PRL-3 protein expression in sinonasal and cutaneous melanoma
Volume: 88 Page(s): 97A - 97A
01/01/2008 Authors: Lim MG; Arbiser JB; Lawson D; Shou C; Chang XJ; Stein IM; Muller S; Cohen C -
OXIDANTS AND ANTIOXIDANTS IN CONTROL OF CELL CYCLE PROGRESSION
Volume: 45 Page(s): S4 - S4
01/01/2008 Authors: Phalen TJ; Newick K; Pass HI; Mossman BT; Shukla A; Arbiser JL; Heintz NH -
Protein Tyrosine Phosphatase Superfamily Redox Sensing Using Active-Site-Directed Probes
Volume: 45 Page(s): S68 - S68
01/01/2008 Authors: Boivin B; Zhang S; Arbiser JL; Zhang Z-Y; Tonks NK -
Angiogenesis in cutaneous lesions of leprosy: implications for treatment.
Arch Dermatol Volume: 143 Page(s): 1527 - 1529
12/01/2007 Authors: Bhandarkar SS; Cohen C; Kuruvila M; Rea TH; Mackelfresh JB; Lee DJ; Modlin RL; Arbiser JL -
Why targeted therapy hasn't worked in advanced cancer.
J Clin Invest Volume: 117 Page(s): 2762 - 2765
10/01/2007 Authors: Arbiser JL -
Synthesis, cytotoxicity, and antiviral activities of new neolignans related to honokiol and magnolol.
Bioorg Med Chem Lett Volume: 17 Page(s): 4428 - 4431
08/15/2007 Authors: Amblard F; Govindarajan B; Lefkove B; Rapp KL; Detorio M; Arbiser JL; Schinazi RF -
Fumagillin: an anti-infective as a parent molecule for novel angiogenesis inhibitors.
Expert Rev Anti Infect Ther Volume: 5 Page(s): 573 - 579
08/01/2007 Authors: Lefkove B; Govindarajan B; Arbiser JL -
Honokiol, a natural plant product, inhibits inflammatory signals and alleviates inflammatory arthritis.
J Immunol Volume: 179 Page(s): 753 - 763
07/15/2007 Authors: Munroe ME; Arbiser JL; Bishop GA -
Honokiol, a natural biphenyl, inhibits in vitro and in vivo growth of breast cancer through induction of apoptosis and cell cycle arrest.
Int J Oncol Volume: 30 Page(s): 1529 - 1537
06/01/2007 Authors: Wolf I; O'Kelly J; Wakimoto N; Nguyen A; Amblard F; Karlan BY; Arbiser JL; Koeffler HP -
Honokiol, a natural plant product, inhibits the bone metastatic growth of human prostate cancer cells.
Cancer Volume: 109 Page(s): 1279 - 1289
04/01/2007 Authors: Shigemura K; Arbiser JL; Sun S-Y; Zayzafoon M; Johnstone PAS; Fujisawa M; Gotoh A; Weksler B; Zhau HE; Chung LWK -
Grp78 (Glucose related protein 78) is a target of Honokiol
Volume: 127 Page(s): S2 - S2
04/01/2007 Authors: Govindarajan B; Lefkove B; Foster D; Aggarwal B; Arbiser J -
AKT1 overexpression in endothelial cells leads to the development of cutaneous vascular malformations in vivo.
Arch Dermatol Volume: 143 Page(s): 504 - 506
04/01/2007 Authors: Perry B; Banyard J; McLaughlin ER; Watnick R; Sohn A; Brindley DN; Obata T; Cantley LC; Cohen C; Arbiser JL -
NADPH oxidase 4 is a key regulator of hemangioma growth in vivo
Volume: 127 Page(s): S2 - S2
04/01/2007 Authors: Bhandarkar SS; Jaconi M; Perry BN; Sohn A; Augustin H; Arbiser J -
Impaired immune effector functions in condylomata
Volume: 127 Page(s): S132 - S132
04/01/2007 Authors: Le Poole I; Denman CJ; Arbiser JL -
Overexpression of Akt converts radial growth melanoma to vertical growth melanoma.
J Clin Invest Volume: 117 Page(s): 719 - 729
03/01/2007 Authors: Govindarajan B; Sligh JE; Vincent BJ; Li M; Canter JA; Nickoloff BJ; Rodenburg RJ; Smeitink JA; Oberley L; Zhang Y -
Lack of extracellular signal-regulated kinase mitogen-activated protein kinase signaling shows a new type of melanoma.
Cancer Res Volume: 67 Page(s): 1502 - 1512
02/15/2007 Authors: Shields JM; Thomas NE; Cregger M; Berger AJ; Leslie M; Torrice C; Hao H; Penland S; Arbiser J; Scott G -
Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphatidylinositol-3-kinase signaling and angiogenesis.
Blood Volume: 109 Page(s): 560 - 565
01/15/2007 Authors: Arbiser JL; Kau T; Konar M; Narra K; Ramchandran R; Summers SA; Vlahos CJ; Ye K; Perry BN; Matter W -
Expression of the neural stem cell markers NG2 and L1 in human angiomyolipoma: are angiomyolipomas neoplasms of stem cells?
Mol Med Volume: 13 Page(s): 160 - 165
01/01/2007 Authors: Lim SD; Stallcup W; Lefkove B; Govindarajan B; Au KS; Northrup H; Lang D; Fisher DE; Patel A; Amin MB -
Mammalian target of rapamycin (mTOR) is activated in cutaneous vascular malformations in vivo.
Lymphat Res Biol Volume: 5 Page(s): 233 - 236
01/01/2007 Authors: Shirazi F; Cohen C; Fried L; Arbiser JL -
Curcumin as an inhibitor of angiogenesis.
Adv Exp Med Biol Volume: 595 Page(s): 185 - 195
01/01/2007 Authors: Bhandarkar SS; Arbiser JL -
Presence of p16 hypermethylation and Epstein-Barr virus infection in transplant-associated hematolymphoid neoplasm of the skin.
J Am Acad Dermatol Volume: 55 Page(s): 794 - 798
11/01/2006 Authors: Arbiser JL; Mann KP; Losken EM; Cohen C; Reddy K; Kokko K; Pollack B; Fan C-Y; O'Reilly F -
The duality of angiogenesis: implications for therapy of human disease.
J Invest Dermatol Volume: 126 Page(s): 2160 - 2166
10/01/2006 Authors: Perry BN; Arbiser JL -
Pharmacologic blockade of angiopoietin-2 is efficacious against model hemangiomas in mice.
J Invest Dermatol Volume: 126 Page(s): 2316 - 2322
10/01/2006 Authors: Perry BN; Govindarajan B; Bhandarkar SS; Knaus UG; Valo M; Sturk C; Carrillo CO; Sohn A; Cerimele F; Dumont D -
Honokiol potentiates apoptosis, suppresses osteoclastogenesis, and inhibits invasion through modulation of nuclear factor-kappaB activation pathway.
Mol Cancer Res Volume: 4 Page(s): 621 - 633
09/01/2006 Authors: Ahn KS; Sethi G; Shishodia S; Sung B; Arbiser JL; Aggarwal BB -
Wilms tumor 1 expression present in most melanomas but nearly absent in nevi.
Arch Dermatol Volume: 142 Page(s): 1031 - 1034
08/01/2006 Authors: Perry BN; Cohen C; Govindarajan B; Cotsonis G; Arbiser JL -
Carbazole is a naturally occurring inhibitor of angiogenesis and inflammation isolated from antipsoriatic coal tar.
J Invest Dermatol Volume: 126 Page(s): 1396 - 1402
06/01/2006 Authors: Arbiser JL; Govindarajan B; Battle TE; Lynch R; Frank DA; Ushio-Fukai M; Perry BN; Stern DF; Bowden GT; Liu A -
Facile purification of honokiol and its antiviral and cytotoxic properties.
J Med Chem Volume: 49 Page(s): 3426 - 3427
06/01/2006 Authors: Amblard F; Delinsky D; Arbiser JL; Schinazi RF -
Sertraline exhibits anti-proliferative activity against B16 mouse and A375 human melanoma cell lines in-vitro
Volume: 126 Page(s): 148 - 148
04/01/2006 Authors: Reddy K; Lefkove B; Arbiser JL -
Collaboration between dominant negative tuberin and p16 deficiency results in development of T cell lymphoma in transgenic mice
Volume: 126 Page(s): 75 - 75
04/01/2006 Authors: Govindarajan B; Arbiser JL; Cohen C; Martin DW -
Wilms tumor 1 (WT1) expression distinguishes nevi from melanoma
Volume: 126 Page(s): 153 - 153
04/01/2006 Authors: Perry B; Cohen C; Govindarajan B; Cotsonis G; Arbiser JL -
Honokiol and Magnolol: New potent antitumor compounds
Volume: 231
03/26/2006 Authors: Amblard F; Delinsky D; Arbiser JL; Schinazi RF -
The natural product honokiol potentiates radiation sensitization induced by siRNA ADAM9 knockdown in prostate cancer cells
Volume: 78 Page(s): S76 - S77
03/01/2006 Authors: Johnstone P; Sung SY; Anderson C; Arbiser J; Chung L -
ACE expression in primary melanoma: Correlation with prognostic parameters and outcome
Volume: 19 Page(s): 81A - 81A
01/01/2006 Authors: Hornsby CD; Bernstein K; Arbiser JL; Cotsonis G; Perry B; Cohen C -
ACE expression in primary melanoma: Correlation with prognostic parameters and outcome
Volume: 86 Page(s): 81A - 81A
01/01/2006 Authors: Hornsby CD; Bernstein K; Arbiser JL; Cotsonis G; Perry B; Cohen C -
Keloids are not angiogenic lesions - Reply
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY Volume: 53 Page(s): 1097 - 1098
12/01/2005 Authors: Arbiser JL -
Keloids are not angiogenic lesions.
J Am Acad Dermatol Volume: 53 Page(s): 1097
12/01/2005 Authors: Beer TW -
Combination therapy of doxycycline and topical tacrolimus for venous ulcers.
Arch Dermatol Volume: 141 Page(s): 1476 - 1477
11/01/2005 Authors: Mackelfresh J; Soon S; Arbiser JL -
Expression of Wilms tumor 1 gene distinguishes vascular malformations from proliferative endothelial lesions.
Arch Dermatol Volume: 141 Page(s): 1297 - 1300
10/01/2005 Authors: Lawley LP; Cerimele F; Weiss SW; North P; Cohen C; Kozakewich HPW; Mulliken JB; Arbiser JL -
Honokiol overcomes conventional drug resistance in human multiple myeloma by induction of caspase-dependent and -independent apoptosis.
Blood Volume: 106 Page(s): 1794 - 1800
09/01/2005 Authors: Ishitsuka K; Hideshima T; Hamasaki M; Raje N; Kumar S; Hideshima H; Shiraishi N; Yasui H; Roccaro AM; Richardson P -
Apolipoprotein D is down-regulated during malignant transformation of neurofibromas.
Hum Pathol Volume: 36 Page(s): 987 - 993
09/01/2005 Authors: Hunter S; Weiss S; Ou C-Y; Jaye D; Young A; Wilcox J; Arbiser JL; Monson D; Goldblum J; Nolen JD -
Naturally occurring proteasome inhibitors from mate tea (Ilex paraguayensis) serve as models for topical proteasome inhibitors.
J Invest Dermatol Volume: 125 Page(s): 207 - 212
08/01/2005 Authors: Arbiser JL; Li X-C; Hossain CF; Nagle DG; Smith DM; Miller P; Govindarajan B; DiCarlo J; Landis-Piwowar KR; Dou QP -
The natural product honokiol induces caspase-dependent apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells.
Blood Volume: 106 Page(s): 690 - 697
07/15/2005 Authors: Battle TE; Arbiser J; Frank DA -
Synthesis and biological evaluation of aromatic enones related to curcumin.
Bioorg Med Chem Volume: 13 Page(s): 4007 - 4013
06/02/2005 Authors: Robinson TP; Hubbard RB; Ehlers TJ; Arbiser JL; Goldsmith DJ; Bowen JP -
Implications of Epstein-Barr Virus (EBV)-induced carcinogenesis on cutaneous inflammation and carcinogenesis: evidence of recurring patterns of angiogenesis and signal transduction.
J Invest Dermatol Volume: 124 Page(s): xi - xii
05/01/2005 Authors: Arbiser JL -
Malignant transformation of human cells by constitutive expression of platelet-derived growth factor-BB.
J Biol Chem Volume: 280 Page(s): 13936 - 13943
04/08/2005 Authors: Govindarajan B; Shah A; Cohen C; Arnold RS; Schechner J; Chung J; Mercurio AM; Alani R; Ryu B; Fan C-Y -
Solenopsin, the alkaloidal component of the fire ant (Solenopsis invicta), is a naturally occurring inhibitor of phosphoinositol-3 kinase
Volume: 124 Page(s): A1 - A1
04/01/2005 Authors: Arbiser JL; Kau T; Konar M; Ramachandran R; Silver PA; Bain J; Cohen P; Gray A; Whitmire D; Tseng P -
Dominant negative tuberin collaborates with Patched (PTCH) deficiency in the development of neoplasia in transgenic mice
Volume: 124 Page(s): A76 - A76
04/01/2005 Authors: Govindarajan B; Arbiser JL; Brat DJ; Andrzej D -
A cyclosporine-sensitive psoriasis-like disease produced in Tie2 transgenic mice.
Am J Pathol Volume: 166 Page(s): 843 - 855
03/01/2005 Authors: Voskas D; Jones N; Van Slyke P; Sturk C; Chang W; Haninec A; Babichev YO; Tran J; Master Z; Chen S -
Transgenic expression of dominant negative tuberin through a strong constitutive promoter results in a tissue-specific tuberous sclerosis phenotype in the skin and brain.
J Biol Chem Volume: 280 Page(s): 5870 - 5874
02/18/2005 Authors: Govindarajan B; Brat DJ; Csete M; Martin WD; Murad E; Litani K; Cohen C; Cerimele F; Nunnelley M; Lefkove B -
PSK and Trx80 inhibit B-cell growth in EBV-infected cord blood mononuclear cells through T cells activated by the monocyte products IL-15 and IL-12.
Blood Volume: 105 Page(s): 1606 - 1613
02/15/2005 Authors: Liu A; Arbiser JL; Holmgren A; Klein G; Klein E -
gli-1 Oncogene is highly expressed in granulomatous skin disorders, including sarcoidosis, granuloma annulare, and necrobiosis lipoidica diabeticorum.
Arch Dermatol Volume: 141 Page(s): 259 - 262
02/01/2005 Authors: Macaron NC; Cohen C; Chen SC; Arbiser JL -
Rapamycin (sirolimus) as a steroid-sparing agent in dermatomyositis.
J Am Acad Dermatol Volume: 52 Page(s): 17 - 19
02/01/2005 Authors: Nadiminti U; Arbiser JL -
Reactive oxygen signaling and MAPK activation distinguish Epstein-Barr Virus (EBV)-positive versus EBV-negative Burkitt's lymphoma.
Proc Natl Acad Sci U S A Volume: 102 Page(s): 175 - 179
01/04/2005 Authors: Cerimele F; Battle T; Lynch R; Frank DA; Murad E; Cohen C; Macaron N; Sixbey J; Smith K; Watnick RS -
Vascular endothelial growth factor (VEGF) and pigment epithelium derived factor (PEDF) in micrometastatic ocular melanoma in a murine model
Volume: 46
01/01/2005 Authors: Yang H; Xu Z; Iuvone PM; Arbiser JL; Crawford SE; Stellmach VM; Grossniklaus HE -
Antiangiogenic agents: studies on fumagillin and curcumin analogs.
Curr Pharm Des Volume: 11 Page(s): 357 - 373
01/01/2005 Authors: Furness MS; Robinson TP; Ehlers T; Hubbard RB; Arbiser JL; Goldsmith DJ; Bowen JP -
Honokiol overcomes conventional drug resistance in human multiple myeloma.
Volume: 104 Page(s): 416A - 416A
11/16/2004 Authors: Ishitsuka K; Hideshima T; Hamasaki M; Noopur R; Shaji K; Hideshima H; Shiraishi N; Richardson P; Munshi NC; Chauhan D -
The natural product honokiol induces caspase-dependent apoptosis in chronic lymphocytic leukmemia (CLL) cells.
Volume: 104 Page(s): 277B - 277B
11/16/2004 Authors: Battle TE; Arbiser J; Frank DA -
Tumor necrosis factor-related apoptosis-inducing ligand can induce apoptosis in subsets of premalignant cells.
Am J Pathol Volume: 165 Page(s): 1613 - 1620
11/01/2004 Authors: Lu X; Arbiser JL; West J; Hoedt-Miller M; Sheridan A; Govindarajan B; Harral JW; Rodman DM; Fouty B -
Involvement of p53 and p16 tumor suppressor genes in recessive dystrophic epidermolysis bullosa-associated squamous cell carcinoma.
J Invest Dermatol Volume: 123 Page(s): 788 - 790
10/01/2004 Authors: Arbiser JL; Fan C-Y; Su X; Van Emburgh BO; Cerimele F; Miller MS; Harvell J; Marinkovich MP -
Keloids demonstrate high-level epidermal expression of vascular endothelial growth factor.
J Am Acad Dermatol Volume: 50 Page(s): 850 - 853
06/01/2004 Authors: Gira AK; Brown LF; Washington CV; Cohen C; Arbiser JL -
Molecular regulation of angiogenesis and tumorigenesis by signal transduction pathways: evidence of predictable and reproducible patterns of synergy in diverse neoplasms.
Semin Cancer Biol Volume: 14 Page(s): 81 - 91
04/01/2004 Authors: Arbiser JL -
Malignant transformation of human cells through an autocrine loop between platelet derived growth factor-BB (PDGF-BB) and PDGFR beta
Volume: 122 Page(s): A17 - A17
03/01/2004 Authors: Govindarajan B; Shah A; Arbiser JL; Cohen C; Schechner J; Chung J; Mercurio A; Alani R -
Overexpression of akt converts radial growth melanoma to vertical growth melanoma
Volume: 122 Page(s): A17 - A17
03/01/2004 Authors: Arbiser JL; Govindarajan B; Slingerland J; Arnold RS; Lambeth DJ -
Angiomotin expression promotes hemangioendothelioma invasion.
Oncogene Volume: 23 Page(s): 1469 - 1473
02/19/2004 Authors: Levchenko T; Bratt A; Arbiser JL; Holmgren L -
Weight loss-induced calciphylaxis: potential role of matrix metalloproteinases.
J Dermatol Volume: 30 Page(s): 915 - 919
12/01/2003 Authors: Munavalli G; Reisenauer A; Moses M; Kilroy S; Arbiser JL -
Regulation of endothelial cell differentiation and transformation by H-Ras.
Exp Cell Res Volume: 291 Page(s): 189 - 200
11/15/2003 Authors: Rennel E; Cross MJ; Klint P; Bai X; Arbiser JL; Gerwins P -
Activation of B-raf in non-malignant nevi predicts a novel tumor suppressor gene in melanoma (MAP kinase phosphatase).
J Invest Dermatol Volume: 121 Page(s): xiv
11/01/2003 Authors: Arbiser JL -
Tuberous sclerosis-associated neoplasms express activated p42/44 mitogen-activated protein (MAP) kinase, and inhibition of MAP kinase signaling results in decreased in vivo tumor growth (vol 9, pg 3469, 2003)
CLINICAL CANCER RESEARCH Volume: 9 Page(s): 5053 - 5053
10/15/2003 Authors: Govindarajan B; Mizesko MC; Miller MS; Onda H; Nunnelley M; Casper K; Brat D; Cohen C; Arbiser JL -
Infectious angiogenesis: Bartonella bacilliformis infection results in endothelial production of angiopoetin-2 and epidermal production of vascular endothelial growth factor.
Am J Pathol Volume: 163 Page(s): 1321 - 1327
10/01/2003 Authors: Cerimele F; Brown LF; Bravo F; Ihler GM; Kouadio P; Arbiser JL -
Honokiol, a small molecular weight natural product, inhibits angiogenesis in vitro and tumor growth in vivo.
J Biol Chem Volume: 278 Page(s): 35501 - 35507
09/12/2003 Authors: Bai X; Cerimele F; Ushio-Fukai M; Waqas M; Campbell PM; Govindarajan B; Der CJ; Battle T; Frank DA; Ye K -
Reversing the angiogenic switch with photodynamic therapy.
J Invest Dermatol Volume: 121 Page(s): xi - xii
09/01/2003 Authors: Arbiser JL -
Role of manganese superoxide dismutase in cancer.
Nat Med Volume: 9 Page(s): 1103
09/01/2003 Authors: Arbiser JL -
Tuberous sclerosis-associated neoplasms express activated p42/44 mitogen-activated protein (MAP) kinase, and inhibition of MAP kinase signaling results in decreased in vivo tumor growth.
Clin Cancer Res Volume: 9 Page(s): 3469 - 3475
08/15/2003 Authors: Govindarajan B; Mizesko MC; Miller MS; Onda H; Nunnelley M; Casper K; Brat D; Cohen C; Arbiser JL -
Cutaneous lesions of secondary syphilis are highly angiogenic.
J Am Acad Dermatol Volume: 48 Page(s): 878 - 881
06/01/2003 Authors: Macaron NC; Cohen C; Chen SC; Arbiser JL -
Malignant transformation of melanocytes to melanoma by constitutive activation of mitogen-activated protein kinase kinase (MAPKK) signaling.
J Biol Chem Volume: 278 Page(s): 9790 - 9795
03/14/2003 Authors: Govindarajan B; Bai X; Cohen C; Zhong H; Kilroy S; Louis G; Moses M; Arbiser JL -
Design, synthesis, and biological evaluation of antiangiogenic compounds: studies of aromatic dienone analogs of curcumin.
Volume: 225 Page(s): U759 - U759
03/01/2003 Authors: Hubbard R; Robinson TP; Ehlers T; Bai XH; Arbiser JL; Goldsmith D; Bowen JP -
Design, synthesis, and biological evaluation of angiogenesis inhibitors: aromatic enone and dienone analogues of curcumin.
Bioorg Med Chem Lett Volume: 13 Page(s): 115 - 117
01/06/2003 Authors: Robinson TP; Ehlers T; Hubbard IV RB; Bai X; Arbiser JL; Goldsmith DJ; Bowen JP -
Molecular pathogenesis of vascular anomalies: classification into three categories based upon clinical and biochemical characteristics.
Lymphat Res Biol Volume: 1 Page(s): 267 - 281
01/01/2003 Authors: Chiller KG; Frieden IJ; Arbiser JL -
High-level expression of vascular endothelial growth factor and its receptors in an aphthous ulcer.
J Cutan Med Surg Volume: 7 Page(s): 225 - 228
01/01/2003 Authors: Arbiser JL; Johnson D; Cohen C; Brown LF -
Mitogen-actived protein kinase activation is an early event in melanoma progression.
Clin Cancer Res Volume: 8 Page(s): 3728 - 3733
12/01/2002 Authors: Cohen C; Zavala-Pompa A; Sequeira JH; Shoji M; Sexton DG; Cotsonis G; Cerimele F; Govindarajan B; Macaron N; Arbiser JL -
SVR angiosarcomas can be rejected by CD4 costimulation dependent and CD8 costimulation independent pathways.
Mol Med Volume: 8 Page(s): 551 - 558
09/01/2002 Authors: Arbiser JL; Bingaman A; Durham M; Cowan S; Cohen C; Zarnegar E; Varma V; Larsen CP -
Functional tyrosine kinase inhibitor profiling: a generally applicable method points to a novel role of platelet-derived growth factor receptor-beta in tuberous sclerosis.
Am J Pathol Volume: 161 Page(s): 781 - 786
09/01/2002 Authors: Arbiser JL; Govindarajan B; Bai X; Onda H; Kazlauskas A; Lim SD; Amin MB; Claesson-Welsh L -
The use of semiempirical methods for conformational studies of novel angiogensis inhibitors.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Volume: 224 Page(s): U507 - U507
08/18/2002 Authors: Bowen JP; Furness S; Robinson TP; Ehlers T; Hubbard R; Fowler C; Arbiser JL; Goldsmith D -
Tyrosine kinase inhibitor profiling: Analysis and therapeutic implications of platelet-derived growth factor signal transduction in tuberous sclerosis-related lesions
JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 119 Page(s): 208 - 208
07/01/2002 Authors: Arbiser JL; Govindarajan B; Bai X; Onda H; Kazlauskas A; Lim SD; Amin MB; Clasesson-Welsh L -
Constitutive activation of MAP kinase kinase signaling results in malignant transformation of melanocytes to melanoma
JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 119 Page(s): 208 - 208
07/01/2002 Authors: Govindarajan B; Bai X; Cohen C; Moses M; Arbiser JL -
Phosphorylation by mitogen-activated protein kinase mediates the hypoxia-induced turnover of the TAL1/SCL transcription factor in endothelial cells.
J Biol Chem Volume: 277 Page(s): 18365 - 18372
05/24/2002 Authors: Tang T; Arbiser JL; Brandt SJ -
Design, synthesis, and biological evaluation of novel angiogenesis inhibitors.
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY Volume: 223 Page(s): U465 - U465
04/07/2002 Authors: Bowen JP; Furness S; Robinson TP; Ehlers T; Arbiser JL; Goldsmith D -
Tuberous sclerosis-associated lesions of the kidney, brain, and skin are angiogenic neoplasms.
J Am Acad Dermatol Volume: 46 Page(s): 376 - 380
03/01/2002 Authors: Arbiser JL; Brat D; Hunter S; D'Armiento J; Henske EP; Arbiser ZK; Bai X; Goldberg G; Cohen C; Weiss SW -
Reactive oxygen generated by Nox1 triggers the angiogenic switch.
Proc Natl Acad Sci U S A Volume: 99 Page(s): 715 - 720
01/22/2002 Authors: Arbiser JL; Petros J; Klafter R; Govindajaran B; McLaughlin ER; Brown LF; Cohen C; Moses M; Kilroy S; Arnold RS -
Cardiovascular disease in neurofibromatosis 1: report of the NF1 Cardiovascular Task Force.
Genet Med Volume: 4 Page(s): 105 - 111
01/01/2002 Authors: Friedman JM; Arbiser J; Epstein JA; Gutmann DH; Huot SJ; Lin AE; McManus B; Korf BR -
Angiogenesis in cutaneous lesions of secondary syphilis
MODERN PATHOLOGY Volume: 15 Page(s): 101A - 101A
01/01/2002 Authors: Macaron NC; Arbiser JL; Cohen C -
Reactive oxygen-induced carcinogenesis causes hypermethylation of p16(Ink4a) and activation of MAP kinase.
Mol Med Volume: 8 Page(s): 1 - 8
01/01/2002 Authors: Govindarajan B; Klafter R; Miller MS; Mansur C; Mizesko M; Bai X; LaMontagne K; Arbiser JL -
Angiosarcoma - One disease or many? A comparison of clinical subtypes
LABORATORY INVESTIGATION Volume: 82 Page(s): 18A - 18A
01/01/2002 Authors: McKenney JK; Paulino AFG; Arbiser J; Folpe AL; Weiss SW -
Angiosarcoma - One disease or many? A comparison of clinical subtypes
MODERN PATHOLOGY Volume: 15 Page(s): 18A - 18A
01/01/2002 Authors: McKenney JK; Paulino AFG; Arbiser J; Folpe AL; Weiss SW -
Angiogenesis in cutaneous lesions of secondary syphilis
LABORATORY INVESTIGATION Volume: 82 Page(s): 101A - 101A
01/01/2002 Authors: Macaron NC; Arbiser JL; Cohen C -
Neuroendocrine lung tumors: grade correlates with proliferation but not angiogenesis.
Mod Pathol Volume: 14 Page(s): 1195 - 1199
12/01/2001 Authors: Arbiser ZK; Arbiser JL; Cohen C; Gal AA -
Molecular signaling pathways critical for tumor cell vasculogenic mimicry
MOLECULAR BIOLOGY OF THE CELL Volume: 12 Page(s): 18A - 19A
11/01/2001 Authors: Hess AR; Seftor EA; Kirschmann DA; Gruman LM; Schneider GB; Arbiser JL; Seftor REB; Hendrix MJC -
Are keloids really "gli-loids"?: High-level expression of gli-1 oncogene in keloids.
J Am Acad Dermatol Volume: 45 Page(s): 707 - 711
11/01/2001 Authors: Kim A; DiCarlo J; Cohen C; McCall C; Johnson D; McAlpine B; Quinn AG; McLaughlin ER; Arbiser JL -
Diffuse dermal angiomatosis of the breast: response to isotretinoin.
J Am Acad Dermatol Volume: 45 Page(s): 462 - 465
09/01/2001 Authors: McLaughlin ER; Morris R; Weiss SW; Arbiser JL -
Microphthalmia transcription factor immunohistochemistry: a useful diagnostic marker in the diagnosis and detection of cutaneous melanoma, sentinel lymph node metastases, and extracutaneous melanocytic neoplasms.
J Am Acad Dermatol Volume: 45 Page(s): 414 - 419
09/01/2001 Authors: O'Reilly FM; Brat DJ; McAlpine BE; Grossniklaus HE; Folpe AL; Arbiser JL -
Overexpression of Bcl-2 in an in vivo model of low grade angiosarcoma
JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 117 Page(s): 492 - 492
08/01/2001 Authors: Schechner J; Pober J; Bothwell A; Wang F; Arbiser J -
The generation and characterization of a cell line derived from a sporadic renal angiomyolipoma: use of telomerase to obtain stable populations of cells from benign neoplasms.
Am J Pathol Volume: 159 Page(s): 483 - 491
08/01/2001 Authors: Arbiser JL; Yeung R; Weiss SW; Arbiser ZK; Amin MB; Cohen C; Frank D; Mahajan S; Herron GS; Yang J -
Collaboration between MAP kinase activation and p16 deletion in a tuberous sclerosis-related sarcoma
JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 117 Page(s): 491 - 491
08/01/2001 Authors: Govindarajan B; Miller M; Kwiatkowski D; Onda H; Nunnelly I; Brown L; Arbiser J -
Akt overexpression confers a tissue invasive phenotype in endothelial cells, but is not required for in vivo growth of angiosarcoma
JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 117 Page(s): 390 - 390
08/01/2001 Authors: McLaughlin E; Cohen C; Obata T; Cantley L; Arbiser J -
Microphthalmia protein: New diagnostic tool in the diagnosis and classification of cutaneous, uveal and central nervous system melanocytic neoplasms.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE Volume: 42 Page(s): S217 - S217
03/15/2001 Authors: Sharara NA; Sippy BD; O'Reilly FM; Brat DJ; McAlpine BE; Grossniklaus HE; Arbiser JL -
Differential expression of active mitogen-activated protein kinase in cutaneous endothelial neoplasms: implications for biologic behavior and response to therapy.
J Am Acad Dermatol Volume: 44 Page(s): 193 - 197
02/01/2001 Authors: Arbiser JL; Weiss SW; Arbiser ZK; Bravo F; Govindajaran B; Caceres-Rios H; Cotsonis G; Recavarren S; Swerlick RA; Cohen C -
Regulation of angiogenesis and tumorigenesis by signal transduction cascades: lessons from benign and malignant endothelial tumors.
J Investig Dermatol Symp Proc Volume: 5 Page(s): 79 - 82
12/01/2000 Authors: Klafter R; Arbiser JL -
Inhibition of MAP kinase kinase causes morphological reversion and dissociation between soft agar growth and in vivo tumorigenesis in angiosarcoma cells.
Am J Pathol Volume: 157 Page(s): 1937 - 1945
12/01/2000 Authors: LaMontagne KR; Moses MA; Wiederschain D; Mahajan S; Holden J; Ghazizadeh H; Frank DA; Arbiser JL -
Immortalized human adult articular chondrocytes maintain cartilage-specific phenotype and responses to interleukin-1beta.
Arthritis Rheum Volume: 43 Page(s): 2189 - 2201
10/01/2000 Authors: Robbins JR; Thomas B; Tan L; Choy B; Arbiser JL; Berenbaum F; Goldring MB -
Altered basic fibroblast growth factor expression in common epidermal neoplasms: examination with in situ hybridization and immunohistochemistry.
J Am Acad Dermatol Volume: 42 Page(s): 973 - 977
06/01/2000 Authors: Arbiser JL; Byers HR; Cohen C; Arbeit J -
VEGF and its receptors are expressed in a pediatric angiosarcoma in a patient with Aicardi's syndrome.
J Invest Dermatol Volume: 114 Page(s): 1209 - 1210
06/01/2000 Authors: McLaughlin ER; Brown LF; Weiss SW; Mulliken JB; Perez-Atayde A; Arbiser JL -
Valproic acid induces human herpesvirus 8 lytic gene expression in BCBL-1 cells.
AIDS Volume: 14 Page(s): 899 - 902
05/05/2000 Authors: Shaw RN; Arbiser JL; Offermann MK -
Overexpression of VEGF 121 in immortalized endothelial cells causes conversion to slowly growing angiosarcoma and high level expression of the VEGF receptors VEGFR-1 and VEGFR-2 in vivo.
Am J Pathol Volume: 156 Page(s): 1469 - 1476
04/01/2000 Authors: Arbiser JL; Larsson H; Claesson-Welsh L; Bai X; LaMontagne K; Weiss SW; Soker S; Flynn E; Brown LF -
The generation of endostatin is mediated by elastase.
Cancer Res Volume: 59 Page(s): 6052 - 6056
12/15/1999 Authors: Wen W; Moses MA; Wiederschain D; Arbiser JL; Folkman J -
Corticotropin-releasing hormone stimulates angiogenesis and epithelial tumor growth in the skin.
J Invest Dermatol Volume: 113 Page(s): 838 - 842
11/01/1999 Authors: Arbiser JL; Karalis K; Viswanathan A; Koike C; Anand-Apte B; Flynn E; Zetter B; Majzoub JA -
Isolation of mouse stromal cells associated with a human tumor using differential diphtheria toxin sensitivity.
Am J Pathol Volume: 155 Page(s): 723 - 729
09/01/1999 Authors: Arbiser JL; Raab G; Rohan RM; Paul S; Hirschi K; Flynn E; Price ER; Fisher DE; Cohen C; Klagsbrun M -
The antiangiogenic agents TNP-470 and 2-methoxyestradiol inhibit the growth of angiosarcoma in mice.
J Am Acad Dermatol Volume: 40 Page(s): 925 - 929
06/01/1999 Authors: Arbiser JL; Panigrathy D; Klauber N; Rupnick M; Flynn E; Udagawa T; D'Amato RJ -
Early detection of melanoma by tumor cell labeling with green fluorescent protein
JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 112 Page(s): 557 - 557
04/01/1999 Authors: Yang H; Galloway T; Chang J; Arbiser J; Ansel JC; Armstron CA -
Thallium inhibits proliferation, modulates signal transduction and alters terminal differentiation in cultured keratinocytes
JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 112 Page(s): 574 - 574
04/01/1999 Authors: Krautmacher C; Peus D; Squillace K; Schilling D; Arbiser J; Pittelkow M -
Clioquinol-zinc chelate: a candidate causative agent of subacute myelo-optic neuropathy.
Mol Med Volume: 4 Page(s): 665 - 670
10/01/1998 Authors: Arbiser JL; Kraeft SK; van Leeuwen R; Hurwitz SJ; Selig M; Dickersin GR; Flint A; Byers HR; Chen LB -
p53 induces angiogenesis-restricted dormancy in a mouse fibrosarcoma.
Oncogene Volume: 17 Page(s): 819 - 824
08/20/1998 Authors: Holmgren L; Jackson G; Arbiser J -
Melanoma. Lessons from metastases.
Arch Dermatol Volume: 134 Page(s): 1027 - 1028
08/01/1998 Authors: Arbiser JL -
Analysis of vascularity of human neurofibromas.
J Am Acad Dermatol Volume: 38 Page(s): 950 - 954
06/01/1998 Authors: Arbiser JL; Flynn E; Barnhill RL -
Curcumin is an in vivo inhibitor of angiogenesis.
Mol Med Volume: 4 Page(s): 376 - 383
06/01/1998 Authors: Arbiser JL; Klauber N; Rohan R; van Leeuwen R; Huang MT; Fisher C; Flynn E; Byers HR -
Basic fibroblast growth factor: a missing link between collagen VII, increased collagenase, and squamous cell carcinoma in recessive dystrophic epidermolysis bullosa.
Mol Med Volume: 4 Page(s): 191 - 195
03/01/1998 Authors: Arbiser JL; Fine JD; Murrell D; Paller A; Connors S; Keough K; Marsh E; Folkman J -
American Academy of Dermatology 1997 Awards for Young Investigators in Dermatology. Signal transduction and regulation of angiogenesis.
J Am Acad Dermatol Volume: 37 Page(s): 772 - 777
11/01/1997 Authors: Arbiser JL -
Signal transduction and regulation of angiogenesis
Volume: 37 Page(s): 772 - 773
11/01/1997 Authors: Arbiser JL -
Reduced expression of ICAM-1 and reactivity to TNF-alpha by endothelial cells transfected with Ha-Ras: A possible mechanism for decreased immune surveillance in a murine model of angiosarcoma.
JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 108 Page(s): 307 - 307
04/01/1997 Authors: Gordon KB; Arbiser JL; Miller SD -
Effects of thallium ion on cellular components of the skin.
J Dermatol Volume: 24 Page(s): 147 - 155
03/01/1997 Authors: Arbiser JL; Alani R; Flynn E; Wooten V; Byers HR -
Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways.
Proc Natl Acad Sci U S A Volume: 94 Page(s): 861 - 866
02/04/1997 Authors: Arbiser JL; Moses MA; Fernandez CA; Ghiso N; Cao Y; Klauber N; Frank D; Brownlee M; Flynn E; Parangi S -
Response of surface markers and resistance to apoptosis in Ha-ras transfected endothelial cells: A possible mechanism for decreased immune surveillance in a mouse model of angiosarcoma.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY Volume: 99 Page(s): 1819 - 1819
01/01/1997 Authors: Gordon KB; Arbiser J; Miller SD -
Black tattoo reaction: the peacock's tale.
J Am Acad Dermatol Volume: 35 Page(s): 477 - 479
09/01/1996 Authors: Tope WD; Arbiser JL; Duncan LM -
Gene gun therapy to introduce genes into endothelial cell tumors in vitro and in vivo.
JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 106 Page(s): 580 - 580
04/01/1996 Authors: Lannutti B; Jandeska S; Sun W; Arbiser J; Paller AS -
Angiogenesis and the skin: a primer.
J Am Acad Dermatol Volume: 34 Page(s): 486 - 497
03/01/1996 Authors: Arbiser JL -
Genetic immunodeficiencies: cutaneous manifestations and recent progress.
J Am Acad Dermatol Volume: 33 Page(s): 82 - 89
07/01/1995 Authors: Arbiser JL -
Leukocytoclastic vasculitis following staphylococcal protein A column immunoadsorption therapy. Two cases and a review of the literature.
Arch Dermatol Volume: 131 Page(s): 707 - 709
06/01/1995 Authors: Arbiser JL; Dzieczkowski JS; Harmon JV; Duncan LM -
THALLIUM ACETATE IS AN INHIBITOR OF ENDOTHELIAL-CELL AND MELANOMA GROWTH
JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 104 Page(s): 630 - 630
04/01/1995 Authors: ARBISER JL; FLYNN E; BYERS HR -
Hemophilus influenzae bacteremia in elderly men with Kaposi's sarcoma: two case reports and a review of the literature.
Cutis Volume: 55 Page(s): 101 - 103
02/01/1995 Authors: Arbiser JL; Katz J -
HAEMOPHILUS-INFLUENZAE BACTEREMIA IN ELDERLY MEN WITH KAPOSIS-SARCOMA - 2 CASE-REPORTS AND A REVIEW OF THE LITERATURE
CUTIS Volume: 55 Page(s): 101 - 103
02/01/1995 Authors: ARBISER JL; KATZ J -
Clofazimine: a review of its medical uses and mechanisms of action.
J Am Acad Dermatol Volume: 32 Page(s): 241 - 247
02/01/1995 Authors: Arbiser JL; Moschella SL -
Occlusion of potent topical steroids.
Arch Dermatol Volume: 131 Page(s): 227
02/01/1995 Authors: Yen A; Raimer SS -
Interleukin-1 beta-modulated gene expression in immortalized human chondrocytes.
J Clin Invest Volume: 94 Page(s): 2307 - 2316
12/01/1994 Authors: Goldring MB; Birkhead JR; Suen LF; Yamin R; Mizuno S; Glowacki J; Arbiser JL; Apperley JF -
Phorbol ester induced rapid attachment and spreading of melanoma cells and the role of extracellular matrix proteins.
Int J Cancer Volume: 57 Page(s): 894 - 900
06/15/1994 Authors: van Leeuwen RL; Dekker SK; Arbiser JL; Vermeer BJ; Bruijn JA; Byers HR -
Use of short-course class 1 topical glucocorticoid under occlusion for the rapid control of erythrodermic psoriasis.
Arch Dermatol Volume: 130 Page(s): 704 - 706
06/01/1994 Authors: Arbiser JL; Grossman K; Kaye E; Arndt KA -
CYTOTOXICITY OF CLIOQUINOL TOWARDS HUMAN-MELANOMA CELLS
JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 102 Page(s): 598 - 598
04/01/1994 Authors: ARBISER JL; VANLEEUWEN RL; FLINT A; BYERS HR -
CURCUMIN BLOCKS PHORBOL ESTER-INDUCED SPREADING OF HUMAN-MELANOMA CELLS IN-VITRO
JOURNAL OF INVESTIGATIVE DERMATOLOGY Volume: 102 Page(s): 598 - 598
04/01/1994 Authors: VANLEEUWEN RL; ARBISER JL; VERMEER BJ; BRUIJN JA; BYERS HR -
Regulation of the ectopically expressed human glycoprotein alpha-subunit gene in the human hepatoma cell line NPLC.
Endocrinology Volume: 134 Page(s): 582 - 587
02/01/1994 Authors: Arbiser JL; Martinez C; Arbiser ZK; Adler GK; Rosen LB; Majzoub JA -
Effects of hydroxyurea and cyclic adenosine monophosphate/protein kinase A inhibitors on the expression of the human chorionic gonadotropin alpha subunit and c-myc genes in choriocarcinoma.
J Endocrinol Invest Volume: 16 Page(s): 849 - 856
12/01/1993 Authors: Arbiser JL; Arbiser ZK; Majzoub JA -
Thrombocytopenia following administration of phenytoin, dexamethasone and cimetidine: a case report and a potential mechanism.
J Intern Med Volume: 234 Page(s): 91 - 94
07/01/1993 Authors: Arbiser JL; Goldstein AM; Gordon D -
Differential regulation of choriocarcinoma gene expression by DNA synthesis inhibitors.
Endocr J Volume: 40 Page(s): 263 - 268
04/01/1993 Authors: Arbiser JL; Arbiser ZK; Majzoub JA -
Regulation of gene expression in choriocarcinoma by methotrexate and hydroxyurea.
Endocrinology Volume: 128 Page(s): 972 - 978
02/01/1991 Authors: Arbiser JL; Arbiser ZK; Majzoub JA -
Species-specific placental corticotropin releasing hormone messenger RNA and peptide expression.
Mol Cell Endocrinol Volume: 62 Page(s): 337 - 341
04/01/1989 Authors: Robinson BG; Arbiser JL; Emanuel RL; Majzoub JA -
Human corticotropin releasing hormone gene is located on the long arm of chromosome 8.
Cytogenet Cell Genet Volume: 47 Page(s): 113 - 116
01/01/1988 Authors: Arbiser JL; Morton CC; Bruns GA; Majzoub JA -
Synthesis and biological activity of 5-phenylselenenyl-substituted pyrimidine nucleosides.
J Med Chem Volume: 29 Page(s): 1293 - 1295
07/01/1986 Authors: Schinazi RF; Arbiser J; Lee JJ; Kalman TI; Prusoff WH