Kukar lab discovers granulins made in lysosome, revealing potential therapeutic targets for neurodegenerative diseases
The Kukar Lab published a paper titled, "Intracellular Proteolysis of Progranulin Generates Stable, Lysosomal Granulins that Are Haploinsufficient in Patients with Frontotemporal Dementia Caused by GRNMutations," in eNeuro.
The paper received a review in ALZFORUM and the Emory News Center.