We are interested in how RNA-binding proteins and non-coding RNAs govern normal brain development and function, and how posttranscriptional dysregulation at the steps of mRNA biogenesis, stability, and translation may lead to malfunction of neurons and glia in mental and neurological diseases. Taking a multidisciplinary strategy and a combination of molecular, cellular, genetics and pharmacological approaches, our current research focuses on the following directions:
- Regulation and function of the human neuronal and glial non-coding transcriptome in neurological and psychiatric diseases
- Molecular mechanisms underlying myelination ad repair
- Translational control in neuronal development, synaptic plasticity and brain disorders