Publications

• Identification of leukemia-enriched signature through the development of a comprehensive pediatric single-cell atlas.
  Nat Commun Volume: 16 Page(s): 4114
  05/02/2025 Authors: Mumme HL; Huang C; Ohlstrom D; Bakhtiari M; Raikar SS; DeRyckere D; Qayed M; Castellino SM; Wechsler DS; Porter CC
• Update on Recommendations for Cancer Screening and Surveillance in Children with Genomic Instability Disorders.
  Clin Cancer Res Volume: 30 Page(s): 5009 - 5020
  11/15/2024 Authors: Nakano Y; Kuiper RP; Nichols KE; Porter CC; Lesmana H; Meade J; Kratz CP; Godley LA; Maese LD; Achatz MI
• Pediatric Cancer Screening in Hereditary Gastrointestinal Cancer Risk Syndromes: An Update from the AACR Childhood Cancer Predisposition Working Group.
  Clin Cancer Res Volume: 30 Page(s): 4566 - 4571
  10/15/2024 Authors: MacFarland SP; Becktell K; Schneider KW; Kuiper RP; Lesmana H; Meade J; Nichols KE; Porter CC; Savage SA; Schultz KA
• Update on Recommendations for Surveillance for Children with Predisposition to Hematopoietic Malignancy.
  Clin Cancer Res Volume: 30 Page(s): 4286 - 4295
  10/01/2024 Authors: Maese LD; Wlodarski MW; Kim SY; Bertuch AA; Bougeard G; Chang VY; Godley LA; Khincha PP; Kuiper RP; Lesmana H
• Clinical Updates and Surveillance Recommendations for DNA Replication Repair Deficiency Syndromes in Children and Young Adults.
  Clin Cancer Res Volume: 30 Page(s): 3378 - 3387
  08/15/2024 Authors: Das A; MacFarland SP; Meade J; Hansford JR; Schneider KW; Kuiper RP; Jongmans MCJ; Lesmana H; Schultz KAP; Nichols KE
• Prototypical innate immune mechanism hijacked by leukemia-initiating mutant stem cells for selective advantage and immune evasion in Ptpn11-associated juvenile myelomonocytic leukemia.
  Res Sq
  08/02/2024 Authors: Zheng H; Zhao P; Tan Z; Yu W-M; Werner J; Stieglitz E; Porter C; Chandrakasan S; Wechsler D; Mendez-Ferrer S
• Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study.
  Lancet Oncol Volume: 25 Page(s): 668 - 682
  05/01/2024 Authors: Ercan AB; Aronson M; Fernandez NR; Chang Y; Levine A; Liu ZA; Negm L; Edwards M; Bianchi V; Stengs L
• Donor-Derived Malignancy and Transplantation Morbidity: Risks of Patient and Donor Genetics in Allogeneic Hematopoietic Stem Cell Transplantation.
  Transplant Cell Ther Volume: 30 Page(s): 255 - 267
  03/01/2024 Authors: Williams LS; Williams KM; Gillis N; Bolton K; Damm F; Deuitch NT; Farhadfar N; Gergis U; Keel SB; Michelis FV
• The T-cell niche tunes immune function through modulation of the cytoskeleton and TCR-antigen forces.
  
  02/02/2024 Authors: Kellner AV; Hunter R; Do P; Eggert J; Jaffe M; Geitgey DK; Lee M; Hamilton JAG; Ross AJ; Ank RS
• Single-cell RNA sequencing distinctly characterizes the wide heterogeneity in pediatric mixed phenotype acute leukemia.
  Genome Med Volume: 15 Page(s): 83
  10/16/2023 Authors: Mumme HL; Raikar SS; Bhasin SS; Thomas BE; Lawrence T; Weinzierl EP; Pang Y; DeRyckere D; Gawad C; Wechsler DS
• Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia.
  Nat Commun Volume: 14 Page(s): 6209
  10/05/2023 Authors: Mumme H; Thomas BE; Bhasin SS; Krishnan U; Dwivedi B; Perumalla P; Sarkar D; Ulukaya GB; Sabnis HS; Park SI
• A novel mobile health application to support cancer surveillance needs of patients and families with cancer predisposition syndromes.
  Pediatr Blood Cancer Volume: 70 Page(s): e30537
  10/01/2023 Authors: Alvarez SJA; Pencheva B; Westfall E; Mwalija C; Parsell M; Greenleaf M; Porter CC; Lam WA; Mannino RG; Mitchell SG
• Siglec-15 Promotes Evasion of Adaptive Immunity in B-cell Acute Lymphoblastic Leukemia.
  Cancer Res Commun Volume: 3 Page(s): 1248 - 1259
  07/01/2023 Authors: Pillsbury CE; Dougan J; Rabe JL; Fonseca JA; Zhou C; Evans AN; Abukharma H; Ichoku O; Gonzalez-Flamenco G; Park SI
• Author Correction: YB1 modulates the DNA damage response in medulloblastoma.
  Sci Rep Volume: 13 Page(s): 9717
  06/15/2023 Authors: McSwain LF; Pillsbury CE; Haji-Seyed-Javadi R; Rath SK; Chen V; Huang T; Shahab SW; Kunhiraman H; Ross J; Price GA
• YB1 modulates the DNA damage response in medulloblastoma.
  Sci Rep Volume: 13 Page(s): 8087
  05/19/2023 Authors: McSwain LF; Pillsbury CE; Haji-Seyed-Javadi R; Rath SK; Chen V; Huang T; Shahab SW; Kunhiraman H; Ross J; Price GA
• Multicolor Light-Induced Immune Activation via Polymer Photocaged Cytokines.
  Biomacromolecules Volume: 24 Page(s): 1164 - 1172
  03/13/2023 Authors: Birnbaum LA; Sullivan EC; Do P; Uricoli B; Raikar SS; Porter CC; Henry CJ; Dreaden EC
• Collaboration to Promote Research and Improve Clinical Care in the Evolving Field of Childhood Cancer Predisposition.
  Cancer Prev Res (Phila) Volume: 15 Page(s): 645 - 652
  10/04/2022 Authors: MacFarland SP; Maese L; Rednam SP; Kamihara J; Perrino MR; Nichols KE; Brodeur GM; Schiffman JD; Plon SE; Diller LR
• Acute myeloid leukemia and dilated cardiomyopathy in a pediatric patient with D-2-hydroxyglutaric aciduria type I.
  Am J Med Genet A Volume: 188 Page(s): 2707 - 2711
  09/01/2022 Authors: Murphey K; George PE; Pencheva B; Porter CC; Wechsler SB; Gambello MJ; Li H
• Revision of RUNX1 variant curation rules.
  Blood Adv Volume: 6 Page(s): 4726 - 4730
  08/23/2022 Authors: Feurstein S; Luo X; Shah M; Walker T; Mehta N; Wu D; Godley LA
• B-cell acute lymphoblastic leukemia promotes an immune suppressive microenvironment that can be overcome by IL-12.
  Sci Rep Volume: 12 Page(s): 11870
  07/13/2022 Authors: Hunter R; Imbach KJ; Zhou C; Dougan J; Hamilton JAG; Chen KZ; Do P; Townsel A; Gibson G; Dreaden EC
• A ROLE FOR SIGLEC 15 IN IMMUNE DSYREGULATION IN LYMPHOMAS
  Volume: 69
  06/01/2022 Authors: Francis D; Dougan J; Pillsbury C; Park S; Liu L; Porter C
• Thrombopoietin-based CAR-T cells demonstrate in vitro and in vivo cytotoxicity to MPL positive acute myelogenous leukemia and hematopoietic stem cells.
  Gene Ther Volume: 29 Page(s): 1 - 12
  05/01/2022 Authors: Zoine JT; Prince C; Story JY; Branella GM; Lytle AM; Fedanov A; Alexander JS; Porter CC; Doering CB; Spencer HT
• Comprehensive Genomic Profiling of High-Risk Pediatric Cancer Patients Has a Measurable Impact on Clinical Care.
  JCO Precis Oncol Volume: 6 Page(s): e2100451
  04/01/2022 Authors: Summers RJ; Castellino SM; Porter CC; MacDonald TJ; Basu GD; Szelinger S; Bhasin MK; Cash T; Carter AB; Castellino RC
• Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.
  Nat Commun Volume: 13 Page(s): 1157
  03/03/2022 Authors: Lee M; Hamilton JAG; Talekar GR; Ross AJ; Michael L; Rupji M; Dwivedi B; Raikar SS; Boss J; Scharer CD
• Germline ETV6 mutation promotes inflammation and disrupts lymphoid development of early hematopoietic progenitors.
  Exp Hematol Volume: 112-113 Page(s): 24 - 34
  01/01/2022 Authors: Zhou C; Uluisik R; Rowley JW; David C; Jones CL; Scharer CD; Noetzli L; Fisher MH; Kirkpatrick GD; Bark K
• Engineered Cytokines for Cancer and Autoimmune Disease Immunotherapy.
  Adv Healthc Mater Volume: 10 Page(s): e2002214
  08/01/2021 Authors: Uricoli B; Birnbaum LA; Do P; Kelvin JM; Jain J; Costanza E; Chyong A; Porter CC; Rafiq S; Dreaden EC
• OBESITY ATTENUTATES T-CELL FUNCTION WHICH IMPACTS T-CELL IMMUNOTHERAPIES IN LYMPHOBLASTIC LEUKEMIA
  Volume: 68 Page(s): S5 - S5
  06/01/2021 Authors: Ross A; Ank R; Lee M; Hamilton J; Story J; Raikar S; Do P; Porter C; Henry C
• Cancer genetic counseling for childhood cancer predisposition is associated with improved levels of knowledge and high satisfaction in parents.
  J Genet Couns Volume: 30 Page(s): 710 - 719
  06/01/2021 Authors: Juarez OA; Pencheva BB; Bellcross C; Schneider KW; Turner J; Porter CC
• IL-412 abrogates mechanisms of immune suppression by B-ALL
  Volume: 206
  05/01/2021 Authors: Hunter R; Henry CJ; Porter C
• The RADx Tech Test Verification Core and the ACME POCT in the Evaluation of COVID-19 Testing Devices: A Model for Progress and Change.
  IEEE Open J Eng Med Biol Volume: 2 Page(s): 142 - 151
  04/28/2021 Authors: Nehl E; Heilman S; Ku D; Gottfried D; Farmer S; Mannino R; Tyburski E; Sullivan J; Suessmith A; Bassit L
• Case report of acutemyeloid leukemia and dilated cardiomyopathy in a pediatric patient with D-2-hydroxyglutaric aciduria type I
  Volume: 132 Page(s): S18 - S19
  04/01/2021 Authors: Ferriero K; George P; Pencheva B; Porter C; Gambello M; Li H
• Cancer Predisposition in Neonates and Infants: Recognition, Tumor Types, and Surveillance.
  Clin Perinatol Volume: 48 Page(s): 1 - 14
  03/01/2021 Authors: Mitchell SG; Pencheva B; Westfall E; Porter CC
• Interleukin-37 improves T-cell-mediated immunity and chimeric antigen receptor T-cell therapy in aged backgrounds.
  Aging Cell Volume: 20 Page(s): e13309
  02/01/2021 Authors: Hamilton JAG; Lee MY; Hunter R; Ank RS; Story JY; Talekar G; Sisroe T; Ballak DB; Fedanov A; Porter CC
• Obesity Attenuates T-Cell Function Which Impacts the Efficacy of T-Cell Based Immunotherapies in Acute Lymphoblastic Leukemia
  Volume: 136
  11/05/2020 Authors: Ross A; Lee M; Hamilton J; Ank R; Do P; Story J; Raikar SS; Dreaden E; Porter CC; Henry CJ
• Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML
  Volume: 136
  11/05/2020 Authors: Thomas BE; Perumalla P; Bhasin SS; Sarkar D; Dwivedi B; Park SI; DeRyckere D; Henry CJ; Raikar SS; Porter CC
• Rapid Assembly and Screening of Multivalent Immune Cell-Redirecting Therapies for Leukemia.
  ACS Comb Sci Volume: 22 Page(s): 533 - 541
  10/12/2020 Authors: Do P; Perdue LA; Chyong A; Hunter R; Dougan J; Henry CJ; Porter CC; Dreaden EC
• ETV6 germline mutations cause HDAC3/NCOR2 mislocalization and upregulation of interferon response genes.
  JCI Insight Volume: 5
  09/17/2020 Authors: Fisher MH; Kirkpatrick GD; Stevens B; Jones C; Callaghan M; Rajpurkar M; Fulbright J; Cooper MA; Rowley J; Porter CC
• Optical Control of Cytokine Signaling via Bioinspired, Polymer-Induced Latency.
  Biomacromolecules Volume: 21 Page(s): 2635 - 2644
  07/13/2020 Authors: Perdue LA; Do P; David C; Chyong A; Kellner AV; Ruggieri A; Kim HR; Salaita K; Lesinski GB; Porter CC
• Germline mutations: many roles in leukemogenesis.
  Curr Opin Hematol Volume: 27 Page(s): 288 - 293
  07/01/2020 Authors: Chen KZ; Kazi R; Porter CC; Qu C-K
• NEXT-GENERATION SEQUENCING REVEALS INCREASED PREVALENCE OF PICALM-MLLT10 FUSIONS IN T-ALL AND T-LLY
  Volume: 67 Page(s): S167 - S167
  06/01/2020 Authors: Summers R; Aumann W; Pauly M; Goldsmith K; Porter C; Worsley R; Graham D; Castellino S; Wechsler D
• Photo-regulated control of cytokine signaling via bioinspired, polymer-induced latency
  Volume: 204
  05/01/2020 Authors: Dreaden EC; Perdue LA; Do P; Chyong A; Salaita K; Lesinski G; Porter CC
• Innate immune populations contribute to effective immune responses against B lymphoblastic leukemia cells
  Volume: 204
  05/01/2020 Authors: Hunter R; Henry CJ; Porter CC
• Promoting anti-tumor immunity via bispecific T cell engaging cytokine (biteokine) therapy
  Volume: 204
  05/01/2020 Authors: Do P; Perdue LA; Chyong A; Henry CJ; Porter CC; Dreaden EC
• Chemical modification strategies for photo-induced control of immune cell signaling
  Volume: 204
  05/01/2020 Authors: Perdue LA; Do P; Chyong A; Costanza E; Kim HR; David C; Kellner A; Salaita K; Lesinski G; Porter CC
• Increased HDAC Activity and c-MYC Expression Mediate Acquired Resistance to WEE1 Inhibition in Acute Leukemia.
  Front Oncol Volume: 10 Page(s): 296
  01/01/2020 Authors: Garcia TB; Uluisik RC; van Linden AA; Jones KL; Venkataraman S; Vibhakar R; Porter CC
• Germline Mutations in ETV6 are Associated with In Vivo cytoplasmic Localization of ETV6 and Cause Transcriptional Dysregulation of Interferon Response Genes
  Volume: 134
  11/13/2019 Authors: Fisher MH; Kirkpatrick G; Jones CL; Stevens BM; Callaghan M; Pietras E; Jones KL; Porter CC; Di Paola J
• Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome.
  Cell Rep Volume: 29 Page(s): 1893 - 1908.e4
  11/12/2019 Authors: Waugh KA; Araya P; Pandey A; Jordan KR; Smith KP; Granrath RE; Khanal S; Butcher ET; Estrada BE; Rachubinski AL
• ClinGen Myeloid Malignancy Variant Curation Expert Panel recommendations for germline RUNX1 variants.
  Blood Adv Volume: 3 Page(s): 2962 - 2979
  10/22/2019 Authors: Luo X; Feurstein S; Mohan S; Porter CC; Jackson SA; Keel S; Chicka M; Brown AL; Kesserwan C; Agarwal A
• ETV6-related thrombocytopenia and leukemia predisposition.
  Blood Volume: 134 Page(s): 663 - 667
  08/22/2019 Authors: Di Paola J; Porter CC
• Stopping Leukemia in Its Tracks: Should Preemptive Hematopoietic Stem-Cell Transplantation be Offered to Patients at Increased Genetic Risk for Acute Myeloid Leukemia?
  Volume: 37 Page(s): 2098 - 2104
  08/20/2019 Authors: Hamilton KV; Maese L; Marron JM; Pulsipher MA; Porter CC; Nichols KE
• Germline Genetics and Childhood Cancer: Emerging Cancer Predisposition Syndromes and Psychosocial Impacts.
  Curr Oncol Rep Volume: 21 Page(s): 85
  08/15/2019 Authors: Mitchell SG; Pencheva B; Porter CC
• IL12 Abrogates Calcineurin-Dependent Immune Evasion during Leukemia Progression.
  Cancer Res Volume: 79 Page(s): 3702 - 3713
  07/15/2019 Authors: Rabe JL; Gardner L; Hunter R; Fonseca JA; Dougan J; Gearheart CM; Leibowitz MS; Lee-Miller C; Baturin D; Fosmire SP
• Siglec-15 is a novel immunomodulatory effector of adaptive immune evasion in acute lymphoblastic leukemia
  Volume: 79
  07/01/2019 Authors: Pillsbury C; Fonseca JA; Dougan J; Gardner L; Rabe J; Gearheart C; Porter CC
• Calcineurin represses IL-12 secretion in acute lymphoblastic leukemia
  Volume: 79
  07/01/2019 Authors: Hunter R; Fonseca J; Dougan J; Gardner LA; Rabe J; Rupji M; Dwivedi B; Henry CJ; Porter CC
• Macrocytic anemia in Lesch-Nyhan disease and its variants.
  Genet Med Volume: 21 Page(s): 353 - 360
  02/01/2019 Authors: Cakmakli HF; Torres RJ; Menendez A; Yalcin-Cakmakli G; Porter CC; Puig JG; Jinnah HA
• Activating PAX gene family paralogs to complement PAX5 leukemia driver mutations.
  PLoS Genet Volume: 14 Page(s): e1007642
  09/01/2018 Authors: Hart MR; Anderson DJ; Porter CC; Neff T; Levin M; Horwitz MS
• The genetic risk of second cancers: should the therapy for acute lymphoblastic leukemia be individualized according to germline genetic makeup?
  Expert Rev Precis Med Drug Dev Volume: 3 Page(s): 339 - 341
  01/01/2018 Authors: Felton KEA; Porter CC; Yang JJ
• Increased activity of both CDK1 and CDK2 is necessary for the combinatorial activity of WEE1 inhibition and cytarabine.
  Leuk Res Volume: 64 Page(s): 30 - 33
  01/01/2018 Authors: Garcia TB; Fosmire SP; Porter CC
• A CRISPR-Cas9 Generated Etv6 mutant Mouse Exhibits Decreased Platelet Counts and Functional Platelet Defects
  Volume: 130
  12/07/2017 Authors: Noetzli L; Rowley JW; Davizon-Castillo P; Kirkpatrick G; Ashworth KJ; Aguila S; Porter CC; Pietras EM; Weyrich AS; Di Paola J
• A Small-Molecule Inhibitor of WEE1, AZD1775, Synergizes with Olaparib by Impairing Homologous Recombination and Enhancing DNA Damage and Apoptosis in Acute Leukemia.
  Mol Cancer Ther Volume: 16 Page(s): 2058 - 2068
  10/01/2017 Authors: Garcia TB; Snedeker JC; Baturin D; Gardner L; Fosmire SP; Zhou C; Jordan CT; Venkataraman S; Vibhakar R; Porter CC
• Surveillance Recommendations for Children with Overgrowth Syndromes and Predisposition to Wilms Tumors and Hepatoblastoma.
  Clin Cancer Res Volume: 23 Page(s): e115 - e122
  07/01/2017 Authors: Kalish JM; Doros L; Helman LJ; Hennekam RC; Kuiper RP; Maas SM; Maher ER; Nichols KE; Plon SE; Porter CC
• Cancer Screening Recommendations and Clinical Management of Inherited Gastrointestinal Cancer Syndromes in Childhood.
  Clin Cancer Res Volume: 23 Page(s): e107 - e114
  07/01/2017 Authors: Achatz MI; Porter CC; Brugires L; Druker H; Frebourg T; Foulkes WD; Kratz CP; Kuiper RP; Hansford JR; Hernandez HS
• Recommendations for Surveillance for Children with Leukemia-Predisposing Conditions.
  Clin Cancer Res Volume: 23 Page(s): e14 - e22
  06/01/2017 Authors: Porter CC; Druley TE; Erez A; Kuiper RP; Onel K; Schiffman JD; Wolfe Schneider K; Scollon SR; Scott HS; Strong LC
• Recommendations for Childhood Cancer Screening and Surveillance in DNA Repair Disorders.
  Clin Cancer Res Volume: 23 Page(s): e23 - e31
  06/01/2017 Authors: Walsh MF; Chang VY; Kohlmann WK; Scott HS; Cunniff C; Bourdeaut F; Molenaar JJ; Porter CC; Sandlund JT; Plon SE
• A Genome-Wide Loss-of-Function Screen Identifies SLC26A2 as a Novel Mediator of TRAIL Resistance.
  Mol Cancer Res Volume: 15 Page(s): 382 - 394
  04/01/2017 Authors: Dimberg LY; Towers CG; Behbakht K; Hotz TJ; Kim J; Fosmire S; Porter CC; Tan A-C; Thorburn A; Ford HL
• IFN- alters the expression of diverse immunity related genes in a cell culture model designed to represent maturing neutrophils.
  PLoS One Volume: 12 Page(s): e0185956
  01/01/2017 Authors: Ellison MA; Gearheart CM; Porter CC; Ambruso DR
• IFN-gamma Alters the Expression of Diverse Immunity Related Genes in a Cell Culture Model of Maturing Neutrophils
  Volume: 128
  12/02/2016 Authors: Ellison MA; Gearheart CM; Porter CC; Ambruso DR
• ETV6 Regulates Pax5 Expression in Early B Cell Development
  Volume: 128
  12/02/2016 Authors: Jones CL; Kirkpatrick G; Fleenor C; Seth W; Noetzli LJ; Fosmire S; Baturin D; Liang X; Hernandez G; Pietras EM
• Germ line mutations associated with leukemias.
  Hematology Am Soc Hematol Educ Program Volume: 2016 Page(s): 302 - 308
  12/02/2016 Authors: Porter CC
• Combined inhibition of Wee1 and Poly(ADP Ribose)Polymerase 1/2 synergistically inhibits acute leukemia cells by enhancing DNA damage and inducing apoptosis in vitro and in vivo
  Volume: 76
  07/01/2016 Authors: Garcia TB; Snedeker JC; Porter CC
• ETV6 represses Pax5 in early B-cell development
  Volume: 76
  07/01/2016 Authors: Jones CL; Fleenor CJ; Welsh S; Noetzli L; Fosmire S; Baturin D; Di Paola J; Hagman JR; Porter CC
• BCR-ABL DRIVES IMMUNE EVASION VIA ACTIVATION OF CALCINEURIN
  Volume: 63 Page(s): S25 - S25
  06/01/2016 Authors: Lee-Miller C; Gardner L; Rabe J; Zelasko S; Jones C; Porter C
• Intraoperative salvage does not affect expression of markers for erythrophagocytosis.
  Transfus Med Volume: 26 Page(s): 147 - 149
  04/01/2016 Authors: Chakravarty PD; Porter C; Cao H; Cairns L; Moss M; Duthie R; Ashcroft P; Jeffrey R; Gibson G; Buchan K
• Genome-wide functional genetic screen with the anticancer agent AMPI-109 identifies PRL-3 as an oncogenic driver in triple-negative breast cancers.
  Oncotarget Volume: 7 Page(s): 15757 - 15771
  03/29/2016 Authors: Gari HH; Gearheart CM; Fosmire S; DeGala GD; Fan Z; Torkko KC; Edgerton SM; Lucia MS; Ray R; Thor AD
• A Dominant Negative Mutation (p.P214L) in ETV6 is Associated with Megakaryocyte and Erythroid Transcript Misregulation
  Volume: 126
  12/03/2015 Authors: Noetzli L; Rowley JW; Callaghan MU; Rajpurkar M; Lee-Sherick AB; Porter CC; Weyrich AS; Di Paola JA
• MAPK signaling cascades mediate distinct glucocorticoid resistance mechanisms in pediatric leukemia.
  Blood Volume: 126 Page(s): 2202 - 2212
  11/05/2015 Authors: Jones CL; Gearheart CM; Fosmire S; Delgado-Martin C; Evensen NA; Bride K; Waanders AJ; Pais F; Wang J; Bhatla T
• AZD1775 sensitizes T cell acute lymphoblastic leukemia cells to cytarabine by promoting apoptosis over DNA repair.
  Oncotarget Volume: 6 Page(s): 28001 - 28010
  09/29/2015 Authors: Ford JB; Baturin D; Burleson TM; Van Linden AA; Kim Y-M; Porter CC
• ETV6 mutations define a new cancer predisposition syndrome.
  Oncotarget Volume: 6 Page(s): 16830 - 16831
  07/10/2015 Authors: Kirkpatrick G; Noetzli L; Di Paola J; Porter CC
• Germline mutations in ETV6 are associated with thrombocytopenia, red cell macrocytosis and predisposition to lymphoblastic leukemia.
  Nat Genet Volume: 47 Page(s): 535 - 538
  05/01/2015 Authors: Noetzli L; Lo RW; Lee-Sherick AB; Callaghan M; Noris P; Savoia A; Rajpurkar M; Jones K; Gowan K; Balduini C
• INF- Enhances Nox2 Activity by Upregulating phox Proteins When Applied to Differentiating PLB-985 Cells but Does Not Induce Nox2 Activity by Itself.
  PLoS One Volume: 10 Page(s): e0136766
  01/01/2015 Authors: Ellison MA; Thurman G; Gearheart CM; Seewald RH; Porter CC; Ambruso DR
• MAPK Signaling Cascades Mediate Distinct Glucocorticoid Resistance Mechanisms in Pediatric B-Precursor ALL
  Volume: 124
  12/06/2014 Authors: Jones CL; Gearheart CM; Fosmire S; Delgado-Martin C; Pais F; Wang J; Bhatla T; Bitterman DS; de Rijk SR; Bourgeois W
• Combined Inhibition of Wee1 and Poly(ADP Ribose) Polymerase1/2 Synergistically Inhibits Acute Myeloid Leukemia Cells By Enhancing DNA Damage and the Induction of Apoptosis
  Volume: 124
  12/06/2014 Authors: Snedeker JC; Burleson TM; Tibes R; Porter CC
• PTP4A3 is oncogenic and modulates triple negative breast cancer growth
  Volume: 74
  10/01/2014 Authors: Gari HH; Ray R; Lucia S; Porter CC; Gearheart CM; Fosmire S; DeGala GD; Fan Z; Ru Y; Thor AD
• Inhibition of calcineurin combined with dasatinib has direct and indirect anti-leukemia effects against BCR-ABL1(+) leukemia.
  Am J Hematol Volume: 89 Page(s): 896 - 903
  09/01/2014 Authors: Gardner LA; Klawitter J; Gregory MA; Zaberezhnyy V; Baturin D; Pollyea DA; Takebe N; Christians U; Gore L; DeGregori J
• STAT3-mediated autophagy dependence identifies subtypes of breast cancer where autophagy inhibition can be efficacious.
  Cancer Res Volume: 74 Page(s): 2579 - 2590
  05/01/2014 Authors: Maycotte P; Gearheart CM; Barnard R; Aryal S; Mulcahy Levy JM; Fosmire SP; Hansen RJ; Morgan MJ; Porter CC; Gustafson DL
• Inhibition of Wee1 sensitizes cancer cells to antimetabolite chemotherapeutics in vitro and in vivo, independent of p53 functionality.
  Mol Cancer Ther Volume: 12 Page(s): 2675 - 2684
  12/01/2013 Authors: Van Linden AA; Baturin D; Ford JB; Fosmire SP; Gardner L; Korch C; Reigan P; Porter CC
• Inhibition Of Wee1 Enhances The Anti-Leukemic Effects Of Antimetabolites In Vitro and In Vivo
  Volume: 122
  11/15/2013 Authors: Ford JB; Fosmire S; van Linden A; Baturin D; Porter CC
• Genome-Wide shRNA Screen Implicates Mitogen Activated Protein Kinase (MAPK) Pathway In Glucocorticoid Resistance In Acute Lymphoblastic Leukemia
  Volume: 122
  11/15/2013 Authors: Courtney JL; Gearheart CM; Susan F; Wang J; Bitterman DS; Bhatla T; Bourgeois W; Porter CC; Carroll WL
• WEE1 AS A THERAPEUTIC TARGET IN ACUTE LEUKEMIA
  PEDIATRIC BLOOD & CANCER Volume: 60 Page(s): S39 - S40
  06/01/2013 Authors: Ford J; Baturin D; Van Linden A; Fosmire S; Porter C
• Targeting developmental pathways in children with cancer: what price success?
  Lancet Oncol Volume: 14 Page(s): e70 - e78
  02/01/2013 Authors: Gore L; DeGregori J; Porter CC
• Knockdown of HPRT for selection of genetically modified human hematopoietic progenitor cells.
  PLoS One Volume: 8 Page(s): e59594
  01/01/2013 Authors: Choudhary R; Baturin D; Fosmire S; Freed B; Porter CC
• Tankyrase and the canonical Wnt pathway protect lung cancer cells from EGFR inhibition.
  Cancer Res Volume: 72 Page(s): 4154 - 4164
  08/15/2012 Authors: Cass-Selves M; Kim J; Zhang Z; Helfrich BA; Gao D; Porter CC; Scarborough HA; Bunn PA; Chan DC; Tan AC
• ATM and MET kinases are synthetic lethal with nongenotoxic activation of p53.
  Nat Chem Biol Volume: 8 Page(s): 646 - 654
  07/01/2012 Authors: Sullivan KD; Padilla-Just N; Henry RE; Porter CC; Kim J; Tentler JJ; Eckhardt SG; Tan AC; DeGregori J; Espinosa JM
• Integrated genomic analyses identify WEE1 as a critical mediator of cell fate and a novel therapeutic target in acute myeloid leukemia.
  Leukemia Volume: 26 Page(s): 1266 - 1276
  06/01/2012 Authors: Porter CC; Kim J; Fosmire S; Gearheart CM; van Linden A; Baturin D; Zaberezhnyy V; Patel PR; Gao D; Tan AC
• A genome-wide shRNA screen identified the WNT pathway as a potential target for combination treatments with BRAF inhibitors in melanoma
  Volume: 132 Page(s): S128 - S128
  05/01/2012 Authors: Almeida AR; Partyka KA; Tan A; Kim J; Porter C; Casas M; Gregory M; Smith S; Fujita M; DeGregori J
• SYNTHETIC LETHALITY SCREENING FOR THE DEVELOPMENT OF RATIONAL COMBINATION THERAPY FOR LEUKEMIA
  Volume: 23 Page(s): 21 - 21
  03/01/2012 Authors: Porter C; Fosmire P; Tan AC; Gregory M; Degregori V
• Genome-Wide shRNA Screen Identifies WEE1 As a Critical Mediator of Cell Fate and Novel Therapeutic Target in AML
  Volume: 118 Page(s): 1494 - 1494
  11/18/2011 Authors: Porter CC; Kim J; Fosmire S; Gearheart CM; van Linden A; Zaberezhnyy V; Gao D; Tan AC; DeGregori J
• Relative fitness of hematopoietic progenitors influences leukemia progression.
  Leukemia Volume: 25 Page(s): 891 - 895
  05/01/2011 Authors: Porter CC; Baturin D; Choudhary R; DeGregori J
• Using a RNAi-based screen to identify targets lobe combined with BRAF inhibitors for treating melanomas
  Volume: 131 Page(s): S85 - S85
  04/01/2011 Authors: Shellman YG; Partyka KA; Porter C; Casas M; Tan A; Kim J; Gregory M; Smith S; Fujita M; DeGregori J
• Knockdown of HPRT Enables Selection of Genetically Modified Human Hematopoietic Progenitor Cells
  Volume: 116 Page(s): 1544 - 1545
  11/19/2010 Authors: Choudhary R; Freed B; DeGregori J; Porter CC
• Irradiation selects for p53-deficient hematopoietic progenitors.
  PLoS Biol Volume: 8 Page(s): e1000324
  03/02/2010 Authors: Marusyk A; Porter CC; Zaberezhnyy V; DeGregori J
• Solution characterization of the extracellular region of CD147 and its interaction with its enzyme ligand cyclophilin A.
  J Mol Biol Volume: 391 Page(s): 518 - 535
  08/21/2009 Authors: Schlegel J; Redzic JS; Porter CC; Yurchenko V; Bukrinsky M; Labeikovsky W; Armstrong GS; Zhang F; Isern NG; DeGregori J
• Evaluation of the Safety and Efficacy of Inhibitory RNA Mediated Purine Analog Resistance Plus 6-Thioguanine for Hematopoietic Cell Selection
  Volume: 17 Page(s): S118 - S118
  05/01/2009 Authors: Porter CC; Zaberezhnyy V; Baturin D; DeGregori J
• Vincristine induced peripheral neuropathy potentiated by voriconazole in a patient with previously undiagnosed CMT1X.
  Pediatr Blood Cancer Volume: 52 Page(s): 298 - 300
  02/01/2009 Authors: Porter CC; Carver AE; Albano EA
• Interfering RNA-mediated purine analog resistance for in vitro and in vivo cell selection.
  Blood Volume: 112 Page(s): 4466 - 4474
  12/01/2008 Authors: Porter CC; DeGregori J
• BCL6 expression correlates with monomorphic histology in children with posttransplantation lymphoproliferative disease.
  J Pediatr Hematol Oncol Volume: 30 Page(s): 684 - 688
  09/01/2008 Authors: Porter CC; Liang X; Gralla J; McGavran L; Albano EA
• Ectopic expression and oncogenesis of Mer tyrosine kinase in E2A-PBX1 expressing B-cell acute lymphoblastic leukemia
  Volume: 25
  06/20/2007 Authors: Sawczyn KK; Porter CC; DeGregori J; Graham DK
• Posttransplant Hodgkin lymphoma preceded by polymorphic posttransplant lymphoproliferative disorder: report of a pediatric case and review of the literature.
  J Pediatr Hematol Oncol Volume: 29 Page(s): 112 - 116
  02/01/2007 Authors: Gheorghe G; Albano EA; Porter CC; McGavran L; Wei Q; Meltesen L; Danielson SM; Liang X
• Impaired DNA replication within progenitor cell pools promotes leukemogenesis.
  PLoS Biol Volume: 3 Page(s): e401
  12/01/2005 Authors: Bilousova G; Marusyk A; Porter CC; Cardiff RD; DeGregori J
• The leukemia oncogene E2a-Hlf impairs checkpoint activation
  Volume: 106 Page(s): 801A - 801A
  11/16/2005 Authors: Porter CC; DeGregori JV
• BCL-6 overexpression predicts poor response to reduced immune suppression therapy in children with post-transplantation lymphoproliferative disease (PTLD).
  Volume: 104 Page(s): 170B - 170B
  11/16/2004 Authors: Porter CC; Liang XY; Albano EA
• Immune responses to influenza immunization in children receiving maintenance chemotherapy for acute lymphoblastic leukemia.
  Pediatr Blood Cancer Volume: 42 Page(s): 36 - 40
  01/01/2004 Authors: Porter CC; Edwards KM; Zhu Y; Frangoul H
• Influenza immunization practices among pediatric oncologists.
  J Pediatr Hematol Oncol Volume: 25 Page(s): 134 - 138
  02/01/2003 Authors: Porter CC; Poehling KA; Hamilton R; Frangoul H; Cooper WO
• Influenza vaccination practices of pediatric oncologists
  PEDIATRIC RESEARCH Volume: 51 Page(s): 258A - 258A
  04/01/2002 Authors: Porter CC; Hamilton RM; Poehling KA; Frangoul H; Cooper WO
• A NOVEL MOBILE APP TO FACILITATE SURVEILLANCE PROTOCOL ADHERENCE IN CANCER PREDISPOSITION PATIENTS
  
  Authors: Mitchell S; Alvarez SA; Pencheva B; Mwalija C; Parsell M; Greenleaf M; Porter C; Lam W; Mannino R