Publications

• Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells.
  Blood
  05/13/2025 Authors: Kasap C; Izgutdina A; Patio-Escobar B; Kang AS; Chilakapati N; Akagi N; Manoj AM; Johnson H; Rashid T; Werner J
• Heme promotes venetoclax resistance in multiple myeloma through MEK-ERK signaling and purine biosynthesis.
  Blood Volume: 145 Page(s): 732 - 747
  02/13/2025 Authors: Nair R; Vu AH; Freer AK; Bhatia KS; Wang D; Savani MR; Matulis SM; Lonial S; Jaye DL; Boise LH
• KDM6A regulates immune response genes in multiple myeloma.
  Blood Volume: 144 Page(s): 1508 - 1520
  10/03/2024 Authors: Dupr-Richer D; Riva A; Barwick BG; Maji S; Casellas Romn H; Li J; De U; Sobh A; Quickstad G; Piper C
• The epigenetic spectrum of IgM gammopathies.
  Blood Volume: 144 Page(s): 1240 - 1241
  09/19/2024 Authors: Barwick BG
• NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome.
  Blood Volume: 144 Page(s): 283 - 295
  07/18/2024 Authors: Sobh A; Encinas E; Patel A; Surapaneni G; Bonilla E; Kaestner C; Poullard J; Clerio M; Vasan K; Freeman T
• Interruption of KLF5 acetylation promotes PTEN-deficient prostate cancer progression by reprogramming cancer-associated fibroblasts.
  J Clin Invest Volume: 134
  05/23/2024 Authors: Zhang B; Liu M; Mai F; Li X; Wang W; Huang Q; Du X; Ding W; Li Y; Barwick BG
• Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells.
  bioRxiv
  02/28/2024 Authors: Kasap C; Izgutdina A; Patio-Escobar B; Kang A; Chilakapati N; Akagi N; Johnson H; Rashid T; Werner J; Barpanda A
• KDM6A Regulates Immune Response Genes in Multiple Myeloma.
  bioRxiv
  02/12/2024 Authors: Dupr-Richer D; Riva A; Maji S; Barwick BG; Romn HC; Sobh A; Quickstad G; Li J; De U; Piper C
• Transcriptional Heterogeneity Overcomes Super-Enhancer Disrupting Drug Combinations in Multiple Myeloma.
  Blood Cancer Discov Volume: 5 Page(s): 34 - 55
  01/08/2024 Authors: Welsh SJ; Barwick BG; Meermeier EW; Riggs DL; Shi C-X; Zhu YX; Sharik ME; Du MT; Abrego Rocha LD; Garbitt VM
• ETV4-Dependent Transcriptional Plasticity Maintains MYC Expression and Results in IMiD Resistance in Multiple Myeloma.
  Blood Cancer Discov Volume: 5 Page(s): 56 - 73
  01/08/2024 Authors: Neri P; Barwick BG; Jung D; Patton JC; Maity R; Tagoug I; Stein CK; Tilmont R; Leblay N; Ahn S
• Integrated epigenetic and transcriptional single-cell analysis of t(11;14) multiple myeloma and its BCL2 dependency.
  Blood Volume: 143 Page(s): 42 - 56
  01/04/2024 Authors: Leblay N; Ahn S; Tilmont R; Poorebrahim M; Maity R; Lee H; Barakat E; Alberge J-B; Sinha S; Jaffer A
• Integrated Genomic Analysis of Primary Prostate Tumor Foci and Corresponding Lymph Node Metastases Identifies Mutations and Pathways Associated with Metastasis.
  Cancers (Basel) Volume: 15
  11/30/2023 Authors: Moreno CS; Winham CL; Alemozaffar M; Klein ER; Lawal IO; Abiodun-Ojo OA; Patil D; Barwick BG; Huang Y; Schuster DM
• Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias.
  Nat Cancer Volume: 4 Page(s): 754 - 773
  05/01/2023 Authors: de Matos Simoes R; Shirasaki R; Downey-Kopyscinski SL; Matthews GM; Barwick BG; Gupta VA; Dupr-Richer D; Yamano S; Hu Y; Sheffer M
• CD8+ Tcell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor.
  Immunity Volume: 56 Page(s): 107 - 124.e5
  01/10/2023 Authors: Prokhnevska N; Cardenas MA; Valanparambil RM; Sobierajska E; Barwick BG; Jansen C; Reyes Moon A; Gregorova P; delBalzo L; Greenwald R
• Inhibition of NADPH Oxidase-ROS Signal using Hyaluronic Acid Nanoparticles for Overcoming Radioresistance in Cancer Therapy.
  ACS Nano Volume: 16 Page(s): 18708 - 18728
  11/22/2022 Authors: Zhu L; Zhao Y; Liu T; Chen M; Qian WP; Jiang B; Barwick BG; Zhang L; Styblo TM; Li X
• Therapeutic implications of mitochondrial stress-induced proteasome inhibitor resistance in multiple myeloma.
  Sci Adv Volume: 8 Page(s): eabq5575
  09/30/2022 Authors: Sharma A; Nair R; Achreja A; Mittal A; Gupta P; Balakrishnan K; Edgar CL; Animasahun O; Dwivedi B; Barwick BG
• adrenergic signaling regulates hematopoietic stem and progenitor cell commitment and therapy sensitivity in multiple myeloma.
  Haematologica Volume: 107 Page(s): 2226 - 2231
  09/01/2022 Authors: Nair R; Subramaniam V; Barwick BG; Gupta VA; Matulis SM; Lonial S; Boise LH; Nooka AK; Muthumalaiappan K; Shanmugam M
• Venetoclax ex vivo functional profiling predicts improved progression-free survival.
  Blood Cancer J Volume: 12 Page(s): 115
  08/04/2022 Authors: Gupta VA; Matulis SM; Barwick BG; Bog RD; Shebelut CW; Shanmugam M; Neri P; Bahlis NJ; Dhodapkar MV; Heffner LT
• PDZ Proteins SCRIB and DLG1 Regulate Myeloma Cell Surface CD86 Expression, Growth, and Survival.
  Mol Cancer Res Volume: 20 Page(s): 1122 - 1136
  07/06/2022 Authors: Moser-Katz T; Gavile CM; Barwick BG; Lee KP; Boise LH
• Multivariant Transcriptome Analysis Identifies Modules and Hub Genes Associated with Poor Outcomes in Newly Diagnosed Multiple Myeloma Patients.
  Cancers (Basel) Volume: 14
  04/29/2022 Authors: Adebayo OO; Dammer EB; Dill CD; Adebayo AO; Oseni SO; Griffen TL; Ohandjo AQ; Yan F; Jain S; Barwick BG
• Aberrant Extrafollicular B Cells, Immune Dysfunction, Myeloid Inflammation, and MyD88-Mutant Progenitors Precede Waldenstrom Macroglobulinemia.
  Blood Cancer Discov Volume: 2 Page(s): 600 - 615
  11/01/2021 Authors: Kaushal A; Nooka AK; Carr AR; Pendleton KE; Barwick BG; Manalo J; McCachren SS; Gupta VA; Joseph NS; Hofmeister CC
• Urolithiasis/Endourology.
  J Urol Volume: 206 Page(s): 1321 - 1324
  11/01/2021 Authors: Assimos DG
• PDZ proteins, SCRIB and DLG1, regulate CD86 surface expression, myeloma growth, and survival
  Volume: 21 Page(s): S79 - S79
  10/01/2021 Authors: Moser-Katz T; Gavile C; Barwick B; Lee K; Boise L
• Whole-genome analysis of TET dioxygenase function in regulatory T cells.
  EMBO Rep Volume: 22 Page(s): e52716
  08/04/2021 Authors: Yue X; Samaniego-Castruita D; Gonzlez-Avalos E; Li X; Barwick BG; Rao A
• Venetoclax sensitivity in multiple myeloma is associated with B-cell gene expression.
  Blood Volume: 137 Page(s): 3604 - 3615
  07/01/2021 Authors: Gupta VA; Barwick BG; Matulis SM; Shirasaki R; Jaye DL; Keats JJ; Oberlton B; Joseph NS; Hofmeister CC; Heffner LT
• Chromatin Accessibility Identifies Regulatory Elements Predictive of Gene Expression and Disease Outcome in Multiple Myeloma.
  Clin Cancer Res Volume: 27 Page(s): 3178 - 3189
  06/01/2021 Authors: Barwick BG; Gupta VA; Matulis SM; Patton JC; Powell DR; Gu Y; Jaye DL; Conneely KN; Lin YC; Hofmeister CC
• The Murine MHC Class II Super Enhancer IA/IE-SE Contains a Functionally Redundant CTCF-Binding Component and a Novel Element Critical for Maximal Expression.
  J Immunol Volume: 206 Page(s): 2221 - 2232
  05/01/2021 Authors: Majumder P; Lee JT; Barwick BG; Patterson DG; Bally APR; Scharer CD; Boss JM
• Ten-eleven translocation protein 1 modulates medulloblastoma progression.
  Genome Biol Volume: 22 Page(s): 125
  04/29/2021 Authors: Kim H; Kang Y; Li Y; Chen L; Lin L; Johnson ND; Zhu D; Robinson MH; McSwain L; Barwick BG
• Oncolytic herpes simplex virus infects myeloma cells invitro and invivo.
  Mol Ther Oncolytics Volume: 20 Page(s): 519 - 531
  03/26/2021 Authors: Ghose J; Dona A; Murtadha M; Gunes EG; Caserta E; Yoo JY; Russell L; Jaime-Ramirez AC; Barwick BG; Gupta VA
• Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer.
  Nat Commun Volume: 12 Page(s): 1714
  03/17/2021 Authors: Zhang B; Li Y; Wu Q; Xie L; Barwick B; Fu C; Li X; Wu D; Xia S; Chen J
• YAP1 Expression in SCLC Defines a Distinct Subtype With T-cell-Inflamed Phenotype.
  J Thorac Oncol Volume: 16 Page(s): 464 - 476
  03/01/2021 Authors: Owonikoko TK; Dwivedi B; Chen Z; Zhang C; Barwick B; Ernani V; Zhang G; Gilbert-Ross M; Carlisle J; Khuri FR
• Downregulation of PA28 induces proteasome remodeling and results in resistance to proteasome inhibitors in multiple myeloma.
  Blood Cancer J Volume: 10 Page(s): 125
  12/14/2020 Authors: Gu Y; Barwick BG; Shanmugam M; Hofmeister CC; Kaufman J; Nooka A; Gupta V; Dhodapkar M; Boise LH; Lonial S
• We need CD38 STAT-JAK.
  Blood Volume: 136 Page(s): 2246 - 2248
  11/12/2020 Authors: Barwick BG; Lonial S
• Chromatin Accessibility Identifies Regulatory Elements Predictive of Oncogene Expression in Multiple Myeloma
  Volume: 136
  11/05/2020 Authors: Barwick BG; Gupta VA; Matulis SM; Patton JC; Powell DR; Gu Y; Jaye DL; Conneely KN; Lin YC; Hofmeister CC
• Increased DNA Repair Gene Expression Correlates with MYC Expression and Inferior Progression-Free Survival in Multiple Myeloma Patients
  Volume: 136
  11/05/2020 Authors: Sweiss K; Barwick BG; Calip GS; Rondelli D; Hofmeister CC; Patel P
• Epigenetically heterogeneous tumor cells direct collective invasion through filopodia-driven fibronectin micropatterning.
  Sci Adv Volume: 6 Page(s): eaaz6197
  07/01/2020 Authors: Summerbell ER; Mouw JK; Bell JSK; Knippler CM; Pedro B; Arnst JL; Khatib TO; Commander R; Barwick BG; Konen J
• CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival.
  Cell Rep Volume: 31 Page(s): 107815
  06/23/2020 Authors: Utley A; Chavel C; Lightman S; Holling GA; Cooper J; Peng P; Liu W; Barwick BG; Gavile CM; Maguire O
• Electron transport chain activity is a predictor and target for venetoclax sensitivity in multiple myeloma.
  Nat Commun Volume: 11 Page(s): 1228
  03/06/2020 Authors: Bajpai R; Sharma A; Achreja A; Edgar CL; Wei C; Siddiqa AA; Gupta VA; Matulis SM; McBrayer SK; Mittal A
• PD-1 Expression during Acute Infection Is Repressed through an LSD1-Blimp-1 Axis.
  J Immunol Volume: 204 Page(s): 449 - 458
  01/15/2020 Authors: Bally APR; Neeld DK; Lu P; Majumder P; Tang Y; Barwick BG; Wang Q; Boss JM
• Gain of Chromosome 1q is associated with early progression in multiple myeloma patients treated with lenalidomide, bortezomib, and dexamethasone.
  Blood Cancer J Volume: 9 Page(s): 94
  11/25/2019 Authors: Schmidt TM; Barwick BG; Joseph N; Heffner LT; Hofmeister CC; Bernal L; Dhodapkar MV; Gupta VA; Jaye DL; Wu J
• Multiple Myeloma Epigenetic Programming Prognostic of Outcome Converges with Loci Reprogrammed in Relapsed/Refractory Disease
  Volume: 134
  11/13/2019 Authors: Barwick BG; Skerget S; Keats JJ; Auclair D; Lonial S; Boise LH; Vertino PM; Powell DR
• The Role of Proteasome Activator PA28 alpha in Multiple Myeloma
  Volume: 134
  11/13/2019 Authors: Gu Y; Barwick BG; Shanmugam M; Hofmeister CC; Kaufman JL; Nooka AK; Gupta VA; Dhodapkar MV; Boise LH; Lonial S
• Integrated phosphoproteomics and transcriptional classifiers reveal hidden RAS signaling dynamics in multiple myeloma.
  Blood Adv Volume: 3 Page(s): 3214 - 3227
  11/12/2019 Authors: Lin Y-HT; Way GP; Barwick BG; Mariano MC; Marcoulis M; Ferguson ID; Driessen C; Boise LH; Greene CS; Wiita AP
• Genetic heterogeneity within collective invasion packs drives leader and follower cell phenotypes.
  J Cell Sci Volume: 132
  10/09/2019 Authors: Zoeller EL; Pedro B; Konen J; Dwivedi B; Rupji M; Sundararaman N; Wang L; Horton JR; Zhong C; Barwick BG
• Antibody secreting cells require EZH2 for maximal metabolism, antibody production, and repression of the B cell transcriptional program
  Volume: 49 Page(s): 320 - 320
  10/01/2019 Authors: Guo M; Price MJ; Patterson DG; Barwick BG; Haines RR; Kania AK; Randall T; Boss JM; Scharer CD
• DNA methylation reprogramming in relapsed/refractory myeloma converges with loci prognostic of survival in newly diagnosed patients
  Volume: 19 Page(s): E57 - E57
  10/01/2019 Authors: Barwick B; Skerget S; Keats J; Auclair D; Lonial S; Boise L; Vertino P
• Integrating Phosphoproteomics and Transcriptional Classifiers Reveals "Hidden Signaling" in Multiple Myeloma Including Differential KRAS and NRAS Mutant Effects
  Volume: 18 Page(s): S44 - S44
  08/13/2019 Authors: Lin Y-HT; Way GP; Barwick BG; Mariano MC; Marcoulis M; Ferguson ID; Driessen C; Boise LH; Greene CS; Wiita AP
• Epigenetic programming underpins B cell dysfunction in human SLE.
  Nat Immunol Volume: 20 Page(s): 1071 - 1082
  08/01/2019 Authors: Scharer CD; Blalock EL; Mi T; Barwick BG; Jenks SA; Deguchi T; Cashman KS; Neary BE; Patterson DG; Hicks SL
• Whole genome DNA methylation analysis of multiple myeloma identifies pervasive hypomethylation and biomarkers of survival
  Volume: 79
  07/01/2019 Authors: Barwick BG; Powell DR; Penaherrera D; Skerget S; Keats JJ; Auclair D; Lonial S; Boise LH; Vertino PM
• Epigenetic programming underpins B cell dysfunction in human SLE
  Volume: 202
  05/01/2019 Authors: Scharer C; Blalock E; Mi T; Barwick B; Jenks S; Neary B; Patterson D; Deguchi T; Lee E-H; Wei C
• PD-1 is negatively regulated by LSD1 through interactions with Blimp-1 during acute viral infection
  Volume: 202
  05/01/2019 Authors: Neeld DK; Bally A; Lu P; Majumder P; Barwick B; Boss JM
• Multiple myeloma immunoglobulin lambda translocations portend poor prognosis.
  Nat Commun Volume: 10 Page(s): 1911
  04/23/2019 Authors: Barwick BG; Neri P; Bahlis NJ; Nooka AK; Dhodapkar MV; Jaye DL; Hofmeister CC; Kaufman JL; Gupta VA; Auclair D
• Cell of Origin and Genetic Alterations in the Pathogenesis of Multiple Myeloma.
  Front Immunol Volume: 10 Page(s): 1121
  01/01/2019 Authors: Barwick BG; Gupta VA; Vertino PM; Boise LH
• Immunoglobulin Lambda Translocations Identify Poor Outcome and IMiD Resistance in Multiple Myeloma and Co-Occur with Hyperdiploidy
  Volume: 132
  11/29/2018 Authors: Barwick BG; Neri P; Bahlis N; Nooka AK; Kaufman JL; Gupta VA; Auclair D; Keats JJ; Lonial S; Vertino PM
• A Role for Syntenin-1 in Multiple Myeloma Cell Survival
  Volume: 132
  11/29/2018 Authors: Moser-Katz T; Gavile CM; Barwick BG; Lonial S; Boise LH
• The Histone Demethylase LSD1 Regulates B Cell Proliferation and Plasmablast Differentiation.
  J Immunol Volume: 201 Page(s): 2799 - 2811
  11/01/2018 Authors: Haines RR; Barwick BG; Scharer CD; Majumder P; Randall TD; Boss JM
• Syntenin regulates multiple myeloma cell survival
  Volume: 78
  07/01/2018 Authors: Moser-Katz T; Gavile CM; Barwick BG; Lonial S; Boise LH
• B cell activation and plasma cell differentiation are inhibited by de novo DNA methylation.
  Nat Commun Volume: 9 Page(s): 1900
  05/15/2018 Authors: Barwick BG; Scharer CD; Martinez RJ; Price MJ; Wein AN; Haines RR; Bally APR; Kohlmeier JE; Boss JM
• The histone demethylase LSD1 regulates B cell proliferation and plasmablast differentiation
  Volume: 200
  05/01/2018 Authors: Haines RR; Barwick BG; Majumder P; Scharer CD; Boss JM
• LSD1 regulates PD-1 expression through interactions with Blimp-1 during acute viral infection
  Volume: 200
  05/01/2018 Authors: Neeld DK; Bally A; Majumder P; Barwick B; Boss JM
• Galactic Cosmic Radiation Induces Persistent Epigenome Alterations Relevant to Human Lung Cancer.
  Sci Rep Volume: 8 Page(s): 6709
  04/30/2018 Authors: Kennedy EM; Powell DR; Li Z; Bell JSK; Barwick BG; Feng H; McCrary MR; Dwivedi B; Kowalski J; Dynan WS
• Plasma cell differentiation is controlled by multiple cell division-coupled epigenetic programs.
  Nat Commun Volume: 9 Page(s): 1698
  04/27/2018 Authors: Scharer CD; Barwick BG; Guo M; Bally APR; Boss JM
• 14-3-3 binds the proteasome, limits proteolytic function and enhances sensitivity to proteasome inhibitors.
  Leukemia Volume: 32 Page(s): 744 - 751
  03/01/2018 Authors: Gu Y; Xu K; Torre C; Samur M; Barwick BG; Rupji M; Arora J; Neri P; Kaufman J; Nooka A
• EZH2 Represses the B Cell Transcriptional Program and Regulates Antibody-Secreting Cell Metabolism and Antibody Production.
  J Immunol Volume: 200 Page(s): 1039 - 1052
  02/01/2018 Authors: Guo M; Price MJ; Patterson DG; Barwick BG; Haines RR; Kania AK; Bradley JE; Randall TD; Boss JM; Scharer CD
• High-Risk Myeloma Is Demarcated By Immunoglobulin Lambda Light Chain Translocations
  Volume: 130
  12/07/2017 Authors: Barwick B; Gupta VA; Auclair D; Keats JJ; Lonial S; Vertino PM; Boise LH
• A B-Cell like Phenotype Is Associated with Sensitivity to Venetoclax in Multiple Myeloma
  Volume: 130
  12/07/2017 Authors: Gupta VA; Barwick B; Newman S; Keats JJ; Auclair D; Matulis S; Rossi MR; Nooka AK; Kaufman JL; Lonial S
• CD86 regulates myeloma cell survival.
  Blood Adv Volume: 1 Page(s): 2307 - 2319
  11/28/2017 Authors: Gavile CM; Barwick BG; Newman S; Neri P; Nooka AK; Lonial S; Lee KP; Boise LH
• LSD1 protects against hippocampal and cortical neurodegeneration.
  Nat Commun Volume: 8 Page(s): 805
  10/09/2017 Authors: Christopher MA; Myrick DA; Barwick BG; Engstrom AK; Porter-Stransky KA; Boss JM; Weinshenker D; Levey AI; Katz DJ
• Pathogenic epigenetic programming of expanded B cell subsets in systemic lupus erythematosus
  Volume: 198
  05/01/2017 Authors: Scharer C; Blalock E; Barwick BG; Gandham B; Neary B; Sanz I; Boss JM
• Oxidative phosphorylation is progressively programmed during plasma cell differentiation
  Volume: 198
  05/01/2017 Authors: Price MJ; Barwick BG; Scharer CD; Boss JM
• MAX is an epigenetic sensor of 5-carboxylcytosine and is altered in multiple myeloma.
  Nucleic Acids Res Volume: 45 Page(s): 2396 - 2407
  03/17/2017 Authors: Wang D; Hashimoto H; Zhang X; Barwick BG; Lonial S; Boise LH; Vertino PM; Cheng X
• Conserved Region C Functions To Regulate PD-1 Expression and Subsequent CD8 T Cell Memory.
  J Immunol Volume: 198 Page(s): 205 - 217
  01/01/2017 Authors: Bally APR; Tang Y; Lee JT; Barwick BG; Martinez R; Evavold BD; Boss JM
• Plasma cell differentiation is coupled to division-dependent DNA hypomethylation and gene regulation.
  Nat Immunol Volume: 17 Page(s): 1216 - 1225
  10/01/2016 Authors: Barwick BG; Scharer CD; Bally APR; Boss JM
• ATAC-seq on biobanked specimens defines a unique chromatin accessibility structure in nave SLE B cells.
  Sci Rep Volume: 6 Page(s): 27030
  06/01/2016 Authors: Scharer CD; Blalock EL; Barwick BG; Haines RR; Wei C; Sanz I; Boss JM
• Epigenetic regulation of histone H3 lysine 27 (H3K27) controls the division-specific timing of gene expression during B cell differentiation
  Volume: 196
  05/01/2016 Authors: Scharer C; Barwick B; Bally A; Boss JM
• Tissue-specific antigens induce dual complementary T cell tolerance mechanisms
  Volume: 196
  05/01/2016 Authors: Martinez RJ; Blanchfield L; Barwick B; Martinez H; Reid H; Evayold BD
• Factors affecting the persistence of drug-induced reprogramming of the cancer methylome.
  Epigenetics Volume: 11 Page(s): 273 - 287
  04/02/2016 Authors: Bell JSK; Kagey JD; Barwick BG; Dwivedi B; McCabe MT; Kowalski J; Vertino PM
• Genome-wide CIITA-binding profile identifies sequence preferences that dictate function versus recruitment.
  Nucleic Acids Res Volume: 43 Page(s): 3128 - 3142
  03/31/2015 Authors: Scharer CD; Choi NM; Barwick BG; Majumder P; Lohsen S; Boss JM
• LSD1 continuously protects the differentiated state of neurons
  Volume: 26
  01/01/2015 Authors: Katz D; Christopher M; Myrick D; Engstrom A; Moudgal R; Barwick B; Levey A
• Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types.
  Genes Immun Volume: 15 Page(s): 543 - 555
  12/01/2014 Authors: Lohsen S; Majumder P; Scharer CD; Barwick BG; Austin JW; Zinzow-Kramer WM; Boss JM
• Wnt signaling in triple negative breast cancer is associated with metastasis.
  BMC Cancer Volume: 13 Page(s): 537
  11/10/2013 Authors: Dey N; Barwick BG; Moreno CS; Ordanic-Kodani M; Chen Z; Oprea-Ilies G; Tang W; Catzavelos C; Kerstann KF; Sledge GW
• Global DNA methylation remodeling accompanies CD8 T cell effector function.
  J Immunol Volume: 191 Page(s): 3419 - 3429
  09/15/2013 Authors: Scharer CD; Barwick BG; Youngblood BA; Ahmed R; Boss JM
• Differential activation of Wnt--catenin pathway in triple negative breast cancer increases MMP7 in a PTEN dependent manner.
  PLoS One Volume: 8 Page(s): e77425
  01/01/2013 Authors: Dey N; Young B; Abramovitz M; Bouzyk M; Barwick B; De P; Leyland-Jones B
• A heterozygous IDH1R132H/WT mutation induces genome-wide alterations in DNA methylation.
  Genome Res Volume: 22 Page(s): 2339 - 2355
  12/01/2012 Authors: Duncan CG; Barwick BG; Jin G; Rago C; Kapoor-Vazirani P; Powell DR; Chi J-T; Bigner DD; Vertino PM; Yan H
• Age-associated DNA methylation in pediatric populations.
  Genome Res Volume: 22 Page(s): 623 - 632
  04/01/2012 Authors: Alisch RS; Barwick BG; Chopra P; Myrick LK; Satten GA; Conneely KN; Warren ST
• Molecular characterisation of formalin-fixed paraffin-embedded (FFPE) breast tumour specimens using a custom 512-gene breast cancer bead array-based platform.
  Br J Cancer Volume: 105 Page(s): 1574 - 1581
  11/08/2011 Authors: Abramovitz M; Barwick BG; Willis S; Young B; Catzavelos C; Li Z; Kodani M; Tang W; Bouzyk M; Moreno CS
• Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma.
  PLoS One Volume: 5 Page(s): e10849
  05/26/2010 Authors: Castellino RC; Barwick BG; Schniederjan M; Buss MC; Becher O; Hambardzumyan D; Macdonald TJ; Brat DJ; Durden DL
• Prostate cancer genes associated with TMPRSS2-ERG gene fusion and prognostic of biochemical recurrence in multiple cohorts.
  Br J Cancer Volume: 102 Page(s): 570 - 576
  02/02/2010 Authors: Barwick BG; Abramovitz M; Kodani M; Moreno CS; Nam R; Tang W; Bouzyk M; Seth A; Leyland-Jones B
• Wnt Signaling Prognosticates Outcome in Breast Cancer Cohorts.
  Volume: 69 Page(s): 509S - 509S
  12/15/2009 Authors: Barwick BG; Kerstann KF; Abramovitz M; Leyland-Jones BR
• Cell line based model to study Wnt-beta catenin pathway in the control of tumor phenotypes in triple negative subset of breast cancer
  CANCER RESEARCH Volume: 69
  05/01/2009 Authors: Dey N; Kerstann K; De P; Barwick B; Marcus A; Moreno C; Abramovitz M; Bouzyk M; Leyland-Jones B
• Identification of matrix metalloproteinase 7 (MMP7) as a selective biomarker of the triple-negative breast cancer subtype
  CANCER RESEARCH Volume: 69
  05/01/2009 Authors: Abramovitz M; Catzavelos C; Li Z; Kodani M; Barwick B; Tang W; Dey N; Moreno C; Bouzyk M; Leyland-Jones B
• Protein-coding and MicroRNA Biomarker Gene Panels Predictive of Clinical Recurrence in Prostate Cancer
  FASEB JOURNAL Volume: 23
  04/01/2009 Authors: Moreno CS; Lai Y-H; Seth A; Osunkoya AO; Zhou W; Petros JA; Johnson BA; Nam RK; Barwick BG; Abramovitz M
• SF1126, A Novel PI3K Inhibitor Results in Downstream Inhibition of the PI3K Axis and Displays Sequen
  CLINICAL LYMPHOMA & MYELOMA Volume: 9 Page(s): S127 - S127
  02/01/2009 Authors: David E; Lonial S; Barwick B; Peng X; Kaufman J; Garlich J
• DNA extraction from formalin-fixed, paraffin-embedded tissue.
  Cold Spring Harb Protoc Volume: 2009 Page(s): pdb.prot5138
  02/01/2009 Authors: Tang W; David FB; Wilson MM; Barwick BG; Leyland-Jones BR; Bouzyk MM
• Differential Wnt pathway activation in triple negative breast cancers comparative to HER2 and hormone positive breast cancers identified from formalin-fixed, paraffin-em bedded tissues
  Volume: 69 Page(s): 73S - 74S
  01/15/2009 Authors: Barwick BG; Abramovitz M; Tang W; Kodani M; Oprea GM; De PK; Catzavelos C; Bouzyk M; Moreno CS; Leyland-Jones B
• Validation of a custom 512-gene breast cancer panel on the illumina-based DASL mRNA expression platform: focus on triple negative breast tumors using RNA from stored formalin-fixed, paraffin blocks.
  Volume: 69 Page(s): 164S - 164S
  01/15/2009 Authors: Abramovitz M; Calzavelos C; Li Z; Kodani M; Barwick B; Tang W; Moreno CS; Bouzyk M; Leyland-Jones B
• Molecular differences in triple negative breast cancer between race/ethnicities.
  Volume: 69 Page(s): 183S - 183S
  01/15/2009 Authors: Bouzyk M; Barwick BG; Abramovitz M; Kodani M; Oprea G; Catzavelos C; Tang W; Moreno CS; Leyland-Jones B
• Discovery of a novel set of prostate cancer-related genes associated with the prognostically important TMPRSS2:ERG fusion gene
  JOURNAL OF CLINICAL ONCOLOGY Volume: 26
  05/20/2008 Authors: Abramovitz M; Nam R; Kodani M; Barwick BG; Moreno C; Tang W; Bouzyk M; Seth A; Leyland-Jones B