Publications

• Hydrogen Peroxide-Releasing Hydrogel-Mediated Cellular Senescence Model for Aging Research.
  Biomater Res Volume: 29 Page(s): 0161
  01/01/2025 Authors: Wei S; Le Thi P; Zhang Y; Park M-Y; Do K; Hoang TTT; Morgan N; Dao T; Heo J; Jo Y
• Large-scale smart bioreactor with fully integrated wireless multivariate sensors and electronics for long-term in situ monitoring of stem cell culture.
  Sci Adv Volume: 10 Page(s): eadk6714
  02/16/2024 Authors: Lee J; Kim H; Lim H-R; Kim YS; Hoang TTT; Choi J; Jeong G-J; Kim H; Herbert R; Soltis I
• Soft implantable printed bioelectronic system for wireless continuous monitoring of restenosis.
  Biosens Bioelectron Volume: 241 Page(s): 115650
  12/01/2023 Authors: Rigo B; Bateman A; Lee J; Kim H; Lee Y; Romero L; Jang YC; Herbert R; Yeo W-H
• Stimuli-responsive pressure-strain sensor-based conductive hydrogel for alleviated non-alcoholic fatty liver disease by scavenging reactive oxygen species in adipose tissue.
  Acta Biomater Volume: 171 Page(s): 406 - 416
  11/01/2023 Authors: Shit A; Park S; Lee Y; Ryplida B; Morgan N; Jang YC; Jin E-J; Park SY
• In vivo shear wave elasticity imaging for assessment of diaphragm function in muscular dystrophy.
  Acta Biomater Volume: 168 Page(s): 277 - 285
  09/15/2023 Authors: Lee J; Myrie NO; Jeong G-J; Han WM; Jang YC; Garca AJ; Emelianov S
• Identifying dysregulated immune cell subsets following volumetric muscle loss with pseudo-time trajectories.
  Commun Biol Volume: 6 Page(s): 749
  07/19/2023 Authors: Hymel LA; Anderson SE; Turner TC; York WY; Zhang H; Liversage AR; Lim HS; Qiu P; Mortensen LJ; Jang YC
• Exercise-Induced Antisenescence and Autophagy Restoration Mitigate Metabolic Disorder-Induced Cardiac Disruption in Mice.
  Med Sci Sports Exerc Volume: 55 Page(s): 376 - 388
  03/01/2023 Authors: Ko J; Jang YC; Quindry J; Guttmann R; Cosio-Lima L; Powers SK; Lee Y
• Glial cell derived neurotrophic factor prevents western diet and palmitate-induced hepatocyte oxidative damage and death through SIRT3.
  Sci Rep Volume: 12 Page(s): 15838
  09/23/2022 Authors: Mwangi SM; Li G; Balasubramaniam A; Merlin D; Dawson PA; Jang YC; Hart CM; Czaja MJ; Srinivasan S
• Development of a stem cell spheroid-laden patch with high retention at skin wound site.
  Bioeng Transl Med Volume: 7 Page(s): e10279
  05/01/2022 Authors: Jeong G-J; Im G-B; Lee T-J; Kim S-W; Jeon HR; Lee D-H; Baik S; Pang C; Kim T-H; Kim D-I
• Neutrophil and natural killer cell imbalances prevent muscle stem cell-mediated regeneration following murine volumetric muscle loss.
  Proc Natl Acad Sci U S A Volume: 119 Page(s): e2111445119
  04/12/2022 Authors: Larouche JA; Fraczek PM; Kurpiers SJ; Yang BA; Davis C; Castor-Macias JA; Sabin K; Anderson S; Harrer J; Hall M
• Nanomaterial for Skeletal Muscle Regeneration.
  Tissue Eng Regen Med Volume: 19 Page(s): 253 - 261
  04/01/2022 Authors: Jeong G-J; Castels H; Kang I; Aliya B; Jang YC
• Wireless Soft Scalp Electronics and Virtual Reality System for Motor Imagery-Based Brain-Machine Interfaces.
  Adv Sci (Weinh) Volume: 8 Page(s): e2101129
  10/01/2021 Authors: Mahmood M; Kwon S; Kim H; Kim Y-S; Siriaraya P; Choi J; Otkhmezuri B; Kang K; Yu KJ; Jang YC
• Delivery of a spheroids-incorporated human dermal fibroblast sheet increases angiogenesis and M2 polarization for wound healing.
  Biomaterials Volume: 275 Page(s): 120954
  08/01/2021 Authors: Kim S-W; Im G-B; Jeong G-J; Baik S; Hyun J; Kim Y-J; Pang C; Jang YC; Bhang SH
• Murine muscle stem cell response to perturbations of the neuromuscular junction are attenuated with aging.
  Elife Volume: 10
  07/29/2021 Authors: Larouche JA; Mohiuddin M; Choi JJ; Ulintz PJ; Fraczek P; Sabin K; Pitchiaya S; Kurpiers SJ; Castor-Macias J; Liu W
• Modulating local S1P receptor signaling as a regenerative immunotherapy after volumetric muscle loss injury.
  J Biomed Mater Res A Volume: 109 Page(s): 695 - 712
  05/01/2021 Authors: Hymel LA; Ogle ME; Anderson SE; San Emeterio CL; Turner TC; York WY; Liu AY; Olingy CE; Sridhar S; Lim HS
• Moderate aerobic exercise training ameliorates impairment of mitochondrial function and dynamics in skeletal muscle of high-fat diet-induced obese mice.
  FASEB J Volume: 35 Page(s): e21340
  02/01/2021 Authors: Heo J-W; No M-H; Cho J; Choi Y; Cho E-J; Park D-H; Kim T-W; Kim C-J; Seo DY; Han J
• Nanofiber-Based Delivery of Bioactive Lipids Promotes Pro-regenerative Inflammation and Enhances Muscle Fiber Growth After Volumetric Muscle Loss.
  Front Bioeng Biotechnol Volume: 9 Page(s): 650289
  01/01/2021 Authors: San Emeterio CL; Hymel LA; Turner TC; Ogle ME; Pendleton EG; York WY; Olingy CE; Liu AY; Lim HS; Sulchek TA
• Cu/Zn Superoxide Dismutase (Sod1) regulates the canonical Wnt signaling pathway.
  Biochem Biophys Res Commun Volume: 534 Page(s): 720 - 726
  01/01/2021 Authors: Chandrasekharan B; Montllor-Albalate C; Colin AE; Andersen JL; Jang YC; Reddi AR
• Superoxide-mediated oxidative stress accelerates skeletal muscle atrophy by synchronous activation of proteolytic systems.
  Geroscience Volume: 42 Page(s): 1579 - 1591
  12/01/2020 Authors: Jang YC; Rodriguez K; Lustgarten MS; Muller FL; Bhattacharya A; Pierce A; Choi JJ; Lee NH; Chaudhuri A; Richardson AG
• Engineered Heterochronic Parabiosis in 3D Microphysiological System for Identification of Muscle Rejuvenating Factors.
  Adv Funct Mater Volume: 30
  11/11/2020 Authors: Lee Y; Choi JJ; Ahn SI; Lee NH; Han WM; Mohiuddin M; Shin EJ; Wood L; Park KD; Kim Y
• Regulation of intracellular transition metal ion level with a pH-sensitive inorganic nanocluster to improve therapeutic angiogenesis by enriching conditioned medium retrieved from human adipose derived stem cells.
  Nano Converg Volume: 7 Page(s): 34
  10/16/2020 Authors: Kim YH; Jung E; Im G-B; Kim Y-J; Kim S-W; Jeong G-J; Jang YC; Park KM; Kim D-I; Yu T
• Breathable, large-area epidermal electronic systems for recording electromyographic activity during operant conditioning of H-reflex.
  Biosens Bioelectron Volume: 165 Page(s): 112404
  10/01/2020 Authors: Kwon Y-T; Norton JJS; Cutrone A; Lim H-R; Kwon S; Choi JJ; Kim HS; Jang YC; Wolpaw JR; Yeo W-H
• Dissecting Murine Muscle Stem Cell Aging through Regeneration Using Integrative Genomic Analysis.
  Cell Rep Volume: 32 Page(s): 107964
  07/28/2020 Authors: Shcherbina A; Larouche J; Fraczek P; Yang BA; Brown LA; Markworth JF; Chung CH; Khaliq M; de Silva K; Choi JJ
• All-printed nanomembrane wireless bioelectronics using a biocompatible solderable graphene for multimodal human-machine interfaces.
  Nat Commun Volume: 11 Page(s): 3450
  07/10/2020 Authors: Kwon Y-T; Kim Y-S; Kwon S; Mahmood M; Lim H-R; Park S-W; Kang S-O; Choi JJ; Herbert R; Jang YC
• The Muscle Stem Cell Mediates Remodeling of Skeletal Muscle Mitochondrial Networks
  Volume: 34
  04/01/2020 Authors: Mohiuddin M; Lee N; Choi J; Anderson S; Han W; Aliya B; Jang Y
• Microfluidic 3D Model of Heterochronic Parabiosis to Study Systemic Regulation of Skeletal Muscle Aging
  Volume: 34
  04/01/2020 Authors: Choi J; Lee Y; Lee N; Han W; Mohiuddin M; Shin E; Anderson S; Park K; Jang Y
• Pyrimethamine conjugated histone deacetylase inhibitors: Design, synthesis and evidence for triple negative breast cancer selective cytotoxicity.
  Bioorg Med Chem Volume: 28 Page(s): 115345
  03/15/2020 Authors: Wu B; Fathi S; Mortley S; Mohiuddin M; Jang YC; Oyelere AK
• Co-delivery of Wnt7a and muscle stem cells using synthetic bioadhesive hydrogel enhances murine muscle regeneration and cell migration during engraftment.
  Acta Biomater Volume: 94 Page(s): 243 - 252
  08/01/2019 Authors: Han WM; Mohiuddin M; Anderson SE; Garca AJ; Jang YC
• Critical Limb Ischemia Induces Remodeling of Skeletal Muscle Motor Unit, Myonuclear-, and Mitochondrial-Domains.
  Sci Rep Volume: 9 Page(s): 9551
  07/02/2019 Authors: Mohiuddin M; Lee NH; Moon JY; Han WM; Anderson SE; Choi JJ; Shin E; Nakhai SA; Tran T; Aliya B
• Determination of a Critical Size Threshold for Volumetric Muscle Loss in the Mouse Quadriceps.
  Tissue Eng Part C Methods Volume: 25 Page(s): 59 - 70
  02/01/2019 Authors: Anderson SE; Han WM; Srinivasa V; Mohiuddin M; Ruehle MA; Moon JY; Shin E; San Emeterio CL; Ogle ME; Botchwey EA
• Attenuation of PKC enhances metabolic activity and promotes expansion of blood progenitors.
  EMBO J Volume: 37
  12/14/2018 Authors: Rao TN; Gupta MK; Softic S; Wang LD; Jang YC; Thomou T; Bezy O; Kulkarni RN; Kahn CR; Wagers AJ
• Correction for Sago et al., High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing.
  Proc Natl Acad Sci U S A Volume: 115 Page(s): E11427
  11/27/2018
• The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle.
  JCI Insight Volume: 3
  11/15/2018 Authors: Kwong JQ; Huo J; Bround MJ; Boyer JG; Schwanekamp JA; Ghazal N; Maxwell JT; Jang YC; Khuchua Z; Shi K
• High-throughput in vivo screen of functional mRNA delivery identifies nanoparticles for endothelial cell gene editing.
  Proc Natl Acad Sci U S A Volume: 115 Page(s): E9944 - E9952
  10/16/2018 Authors: Sago CD; Lokugamage MP; Paunovska K; Vanover DA; Monaco CM; Shah NN; Gamboa Castro M; Anderson SE; Rudoltz TG; Lando GN
• Synthetic matrix enhances transplanted satellite cell engraftment in dystrophic and aged skeletal muscle with comorbid trauma.
  Sci Adv Volume: 4 Page(s): eaar4008
  08/01/2018 Authors: Han WM; Anderson SE; Mohiuddin M; Barros D; Nakhai SA; Shin E; Amaral IF; Pgo AP; Garca AJ; Jang YC
• Detecting the functional complexities between high-density lipoprotein mimetics.
  Biomaterials Volume: 170 Page(s): 58 - 69
  07/01/2018 Authors: Sei YJ; Ahn J; Kim T; Shin E; Santiago-Lopez AJ; Jang SS; Jeon NL; Jang YC; Kim Y
• Long-term resistance exercise-induced muscular hypertrophy is associated with autophagy modulation in rats.
  J Physiol Sci Volume: 68 Page(s): 269 - 280
  05/01/2018 Authors: Kwon I; Jang Y; Cho J-Y; Jang YC; Lee Y
• Engineered matrices for skeletal muscle satellite cell engraftment and function.
  Matrix Biol Volume: 60-61 Page(s): 96 - 109
  07/01/2017 Authors: Han WM; Jang YC; Garca AJ
• Implantable Biomimetic Niche for Satellite Cell Transplantation
  Volume: 31
  04/01/2017 Authors: Jang YC; Han W; Shin E; Garcia A
• Transcriptional and Chromatin Dynamics of Muscle Regeneration after Severe Trauma.
  Stem Cell Reports Volume: 7 Page(s): 983 - 997
  11/08/2016 Authors: Aguilar CA; Pop R; Shcherbina A; Watts A; Matheny RW; Cacchiarelli D; Han WM; Shin E; Nakhai SA; Jang YC
• Overexpression of nutrient sensor, AMP activated kinase (AMPK), in skeletal muscle enhances muscle stem cell transplantation efficiency
  Volume: 30
  04/01/2016 Authors: Kang G; Lee D; Liu E; Jang YC
• Rejuvenation of aged neuromuscular junctions (NMJ) by exposure to a young systemic environment
  Volume: 30
  04/01/2016 Authors: Shin EJ; Wagers A; Jang YC
• Liver specific expression of Cu/ZnSOD extends the lifespan of Sod1 null mice.
  Mech Ageing Dev Volume: 154 Page(s): 1 - 8
  03/01/2016 Authors: Zhang Y; Liu Y; Walsh M; Bokov A; Ikeno Y; Jang YC; Perez VI; Van Remmen H; Richardson A
• Poor Repair of Skeletal Muscle in Aging Mice Reflects a Defect in Local, Interleukin-33-Dependent Accumulation of Regulatory T Cells.
  Immunity Volume: 44 Page(s): 355 - 367
  02/16/2016 Authors: Kuswanto W; Burzyn D; Panduro M; Wang KK; Jang YC; Wagers AJ; Benoist C; Mathis D
• High-level Gpr56 expression is dispensable for the maintenance and function of hematopoietic stem and progenitor cells in mice.
  Stem Cell Res Volume: 14 Page(s): 307 - 322
  05/01/2015 Authors: Rao TN; Marks-Bluth J; Sullivan J; Gupta MK; Chandrakanthan V; Fitch SR; Ottersbach K; Jang YC; Piao X; Kulkarni RN
• Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle.
  Science Volume: 344 Page(s): 649 - 652
  05/09/2014 Authors: Sinha M; Jang YC; Oh J; Khong D; Wu EY; Manohar R; Miller C; Regalado SG; Loffredo FS; Pancoast JR
• A special population of regulatory T cells potentiates muscle repair.
  Cell Volume: 155 Page(s): 1282 - 1295
  12/05/2013 Authors: Burzyn D; Kuswanto W; Kolodin D; Shadrach JL; Cerletti M; Jang Y; Sefik E; Tan TG; Wagers AJ; Benoist C
• Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD.
  Aging Cell Volume: 11 Page(s): 770 - 782
  10/01/2012 Authors: Jang YC; Liu Y; Hayworth CR; Bhattacharya A; Lustgarten MS; Muller FL; Chaudhuri A; Qi W; Li Y; Huang J-Y
• Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels.
  Biochem Biophys Res Commun Volume: 422 Page(s): 515 - 521
  06/08/2012 Authors: Lustgarten MS; Bhattacharya A; Muller FL; Jang YC; Shimizu T; Shirasawa T; Richardson A; Van Remmen H
• Short-term calorie restriction enhances skeletal muscle stem cell function.
  Cell Stem Cell Volume: 10 Page(s): 515 - 519
  05/04/2012 Authors: Cerletti M; Jang YC; Finley LWS; Haigis MC; Wagers AJ
• PGC-1 protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model.
  Muscle Nerve Volume: 44 Page(s): 947 - 956
  12/01/2011 Authors: Liang H; Ward WF; Jang YC; Bhattacharya A; Bokov AF; Li Y; Jernigan A; Richardson A; Van Remmen H
• Age-related Changes in Neurotrophic Factors Expression in Skeletal Muscle Undergoing Atrophy
  Volume: 51 Page(s): S79 - S80
  11/01/2011 Authors: Shi Y; Liu Y; Li Y; Hamilton RT; Jernigan AL; Jang YC; Van Remmen H
• MnSOD deficiency results in elevated oxidative stress and decreased mitochondrial function but does not lead to muscle atrophy during aging.
  Aging Cell Volume: 10 Page(s): 493 - 505
  06/01/2011 Authors: Lustgarten MS; Jang YC; Liu Y; Qi W; Qin Y; Dahia PL; Shi Y; Bhattacharya A; Muller FL; Shimizu T
• Increased mitochondrial matrix-directed superoxide production by fatty acid hydroperoxides in skeletal muscle mitochondria.
  Free Radic Biol Med Volume: 50 Page(s): 592 - 601
  03/01/2011 Authors: Bhattacharya A; Lustgarten M; Shi Y; Liu Y; Jang YC; Pulliam D; Jernigan AL; Van Remmen H
• Age-associated alterations of the neuromuscular junction.
  Volume: 46 Page(s): 193 - 198
  01/01/2011 Authors: Jang YC; Van Remmen H
• Skeletal muscle stem cells: effects of aging and metabolism on muscle regenerative function.
  Cold Spring Harb Symp Quant Biol Volume: 76 Page(s): 101 - 111
  01/01/2011 Authors: Jang YC; Sinha M; Cerletti M; Dall'Osso C; Wagers AJ
• Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration.
  FASEB J Volume: 24 Page(s): 1376 - 1390
  05/01/2010 Authors: Jang YC; Lustgarten MS; Liu Y; Muller FL; Bhattacharya A; Liang H; Salmon AB; Brooks SV; Larkin L; Hayworth CR
• Calorie Restriction (CR) Protects against Oxidative Stress-induced Muscle Atrophy by Preserving Mitochondrial Function and Muscle Integrity Even in the Absence of Antioxidant Enzyme CuZnSOD
  Volume: 49 Page(s): S81 - S81
  01/01/2010 Authors: Jang YC; Lustgarten M; Liu Y; Van Remmen H
• Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity.
  Am J Physiol Cell Physiol Volume: 297 Page(s): C1520 - C1532
  12/01/2009 Authors: Lustgarten MS; Jang YC; Liu Y; Muller FL; Qi W; Steinhelper M; Brooks SV; Larkin L; Shimizu T; Shirasawa T
• Overexpression of Mn superoxide dismutase does not increase life span in mice.
  J Gerontol A Biol Sci Med Sci Volume: 64 Page(s): 1114 - 1125
  11/01/2009 Authors: Jang YC; Prez VI; Song W; Lustgarten MS; Salmon AB; Mele J; Qi W; Liu Y; Liang H; Chaudhuri A
• Glutathione peroxidase 4 differentially regulates the release of apoptogenic proteins from mitochondria.
  Free Radic Biol Med Volume: 47 Page(s): 312 - 320
  08/01/2009 Authors: Liang H; Ran Q; Jang YC; Holstein D; Lechleiter J; McDonald-Marsh T; Musatov A; Song W; Van Remmen H; Richardson A
• The mitochondrial theory of aging: insight from transgenic and knockout mouse models.
  Exp Gerontol Volume: 44 Page(s): 256 - 260
  04/01/2009 Authors: Jang YC; Van Remmen H
• Denervation induces cytosolic phospholipase A2-mediated fatty acid hydroperoxide generation by muscle mitochondria.
  J Biol Chem Volume: 284 Page(s): 46 - 55
  01/02/2009 Authors: Bhattacharya A; Muller FL; Liu Y; Sabia M; Liang H; Song W; Jang YC; Ran Q; Van Remmen H
• Superoxide in vivo Accelerates Age-Associated Muscle Atrophy through Mitochondrial Dysfunction and Neuromuscular Junction Degeneration
  Volume: 47 Page(s): S92 - S93
  01/01/2009 Authors: Jang YC; Lustgarten M; Muller F; Liu Y; Richardson A; Van Remmen H
• Fatty acid hydroperoxide increases ROS production and induces cytochrome C release in skeletal muscle mitochondria
  Volume: 22
  04/01/2008 Authors: Bhattacharya A; Liu Y; Muller F; Perez V; Jang YC; Ran Q; Van Remmen H
• Oxidative stress induced mitochondrial dysfunction leads to age related loss of muscle mass via myonuclear apoptosis and proteolysis
  Volume: 22
  04/01/2008 Authors: Jang YC; Muller FL; Hayworth C; Liu Y; Richardson A; Van Remmen H
• High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates.
  Biochem J Volume: 409 Page(s): 491 - 499
  01/15/2008 Authors: Muller FL; Liu Y; Abdul-Ghani MA; Lustgarten MS; Bhattacharya A; Jang YC; Van Remmen H
• Mitochondrial dysfunction leads to age dependent loss of muscle mass via apoptotic myonuclear deletion and proteolysis in mice lacking SOD1 (CuZnSOD)
  Volume: 29 Page(s): 106 - 107
  09/01/2007 Authors: Jang YC; Muller FL; Li Y; Huang TT; Van Remmen H
• Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production.
  Am J Physiol Regul Integr Comp Physiol Volume: 293 Page(s): R1159 - R1168
  09/01/2007 Authors: Muller FL; Song W; Jang YC; Liu Y; Sabia M; Richardson A; Van Remmen H
• Trends in oxidative aging theories.
  Free Radic Biol Med Volume: 43 Page(s): 477 - 503
  08/15/2007 Authors: Muller FL; Lustgarten MS; Jang Y; Richardson A; Van Remmen H
• Exercise by lifelong voluntary wheel running reduces subsarcolemmal and interfibrillar mitochondrial hydrogen peroxide production in the heart.
  Am J Physiol Regul Integr Comp Physiol Volume: 289 Page(s): R1564 - R1572
  12/01/2005 Authors: Judge S; Jang YM; Smith A; Selman C; Phillips T; Speakman JR; Hagen T; Leeuwenburgh C
• Life long calorie restriction attenuates protein oxidation and endoplasmic/sarcoplasmic reticulum stress induced apoptosis in heart with age
  Volume: 19 Page(s): A1667 - A1667
  03/07/2005 Authors: Jang YC; Leeuwenburgh C
• Doxorubicin treatment in vivo activates caspase-12 mediated cardiac apoptosis in both male and female rats.
  FEBS Lett Volume: 577 Page(s): 483 - 490
  11/19/2004 Authors: Jang YM; Kendaiah S; Drew B; Phillips T; Selman C; Julian D; Leeuwenburgh C