MACS/WIHS Combined Cohort Study (MWCCS)
Multicenter AIDS Cohort Study/Women’s Interagency HIV Study Combined Cohort Study

2019
MACS/WIHS Combined Cohort Study
The NIH combined the Multicenter AIDS Cohort Study (MACS) and the Women’s Interagency HIV Study (WIHS) into the current MWCCS. It is a prospective observational cohort study designed to study the impact of chronic health conditions – including heart, lung, blood, and sleep disorders – that affect men and women living with HIV.
2013
Atlanta added as new WIHS Site
In conjunction with enrollment wave WIHS V, the Atlanta GA site was added as one of four new Southern sites
1994
WIHS Begins Enrollment
WIHS Enrollment WAVE I of women living with or affected by HIV were enrolled.
1993
Women’s Interagency HIV Study (WIHS) was established
The NIH established the Women’s Interagency HIV Study (WIHS) to study the impact and progression of HIV infection among women in response to the rising number of AIDS cases and the relative lack of clinical, behavioral, and epidemiological data in this population.
1983
Multicenter AIDS Cohort Study (MACS), was established
The Multicenter AIDS Cohort Study (MACS) was a longitudinal study of HIV-1 infection among gay and bisexual men in the United States. The MACS began in 1984 and has enrolled more than 7,300 study participants who were evaluated every six months.