MACS/WIHS Combined Cohort Study (MWCCS)

Multicenter AIDS Cohort Study/Women’s Interagency HIV Study Combined Cohort Study

What is the goal of MACS/WIHS Combined Cohort Study?

The Multicenter AIDS Cohort Study (MACS) / Women’s Interagency HIV Study (WIHS) Combined Cohort Study (MWCCS) is a collaborative research effort that aims to understand and reduce the impact of chronic health conditions—including heart, lung, blood, and sleep (HLBS) disorders—that affect people living with HIV.

“The MACS/WIHS CCS is an exciting, trans-NIH study of chronic conditions related to HIV infection in this era of effective antiretroviral therapy,” - Dr. Sean Altekruse, the Project Officer at NIH-NHLBI.

Atlanta MWCCS Summer Newsletter

Check out the latest participant newsletter!

2019 MACS/WIHS Combined Cohort Study

The NIH combined the Multicenter AIDS Cohort Study (MACS) and the Women’s Interagency HIV Study (WIHS) into the current MWCCS. It is a prospective observational cohort study designed to study the impact of chronic health conditions – including heart, lung, blood, and sleep disorders – that affect men and women living with HIV.

1994 WIHS Begins Enrollment

WIHS Enrollment WAVE I of women living with or affected by HIV were enrolled.

1993 Women’s Interagency HIV Study (WIHS) was established

The NIH established the Women’s Interagency HIV Study (WIHS) to study the impact and progression of HIV infection among women in response to the rising number of AIDS cases and the relative lack of clinical, behavioral, and epidemiological data in this population.

1983 Multicenter AIDS Cohort Study (MACS) was established

The Multicenter AIDS Cohort Study (MACS) was a longitudinal study of HIV-1 infection among gay and bisexual men in the United States. The MACS began in 1984 and has enrolled more than 7,300 study participants who were evaluated every six months.

2013 Atlanta added as new WIHS Site

In conjunction with enrollment wave WIHS V, the Atlanta GA site was added as one of four new Southern sites