2023
CSF ferritin in the clinicopathological progression of Alzheimer's disease and associations with APOE and inflammation biomarkers.
J Neurol Neurosurg Psychiatry Volume: 94 Page(s): 211 - 219
03/01/2023 Authors: Ayton S; Janelidze S; Kalinowski P; Palmqvist S; Belaidi AA; Stomrud E; Roberts A; Roberts B; Hansson O; Bush AI
Quantitative proteomics of tau and A in detergent fractions from Alzheimer's disease brains.
J Neurochem Volume: 164 Page(s): 529 - 552
02/01/2023 Authors: Mukherjee S; Dubois C; Perez K; Varghese S; Birchall IE; Leckey M; Davydova N; McLean C; Nisbet RM; Roberts BR
2022
Enhanced ion mobility resolution of Abeta isomers from human brain using high-resolution demultiplexing software.
Anal Bioanal Chem Volume: 414 Page(s): 5683 - 5693
07/01/2022 Authors: Mukherjee S; Fjeldsted JC; Masters CL; Roberts BR
Sulfur- and phosphorus-standardized metal quantification of biological specimens using inductively coupled plasma mass spectrometry.
STAR Protoc Volume: 3 Page(s): 101334
06/17/2022 Authors: Lane A; Gokhale A; Werner E; Roberts A; Freeman A; Roberts B; Faundez V
The Neuroinflammatory Acute Phase Response in Parkinsonian-Related Disorders.
Mov Disord Volume: 37 Page(s): 993 - 1003
05/01/2022 Authors: Ayton S; Hall S; Janelidze S; Kalinowski P; Palmqvist S; Belaidi AA; Roberts B; Roberts A; Stomrud E; Bush AI
Quantitative Phosphoproteomics Reveals Extensive Protein Phosphorylation Dysregulation in the Cerebral Cortex of Huntington's Disease Mice Prior to Onset of Symptoms.
Mol Neurobiol Volume: 59 Page(s): 2456 - 2471
04/01/2022 Authors: Mees I; Tran H; Roberts A; Lago L; Li S; Roberts BR; Hannan AJ; Renoir T
Author Correction: Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer's disease.
Nat Commun Volume: 13 Page(s): 834
02/07/2022 Authors: Roe JM; Vidal-Pieiro D; Srensen ; Brandmaier AM; Dzel S; Gonzalez HA; Kievit RA; Knights E; Khn S; Lindenberger U
Proteome Sci Volume: 20 Page(s): 2
01/26/2022 Authors: Laffoon SB; Doecke JD; Roberts AM; Vance JA; Reeves BD; Pertile KK; Rumble RL; Fowler CJ; Trounson B; Ames D
2021
Differential protein expression due to Se deficiency and Se toxicity in rat liver.
J Nutr Biochem Volume: 98 Page(s): 108831
12/01/2021 Authors: Cardoso BR; Lago L; Dordevic AL; Kapp EA; Raines AM; Sunde RA; Roberts BR
Antisense oligonucleotide therapy reduces seizures and extends life span in an SCN2A gain-of-function epilepsy model.
J Clin Invest Volume: 131
12/01/2021 Authors: Li M; Jancovski N; Jafar-Nejad P; Burbano LE; Rollo B; Richards K; Drew L; Sedo A; Heighway J; Pachernegg S
A six-metabolite panel as potential blood-based biomarkers for Parkinson's disease.
NPJ Parkinsons Dis Volume: 7 Page(s): 94
10/14/2021 Authors: Klatt S; Doecke JD; Roberts A; Boughton BA; Masters CL; Horne M; Roberts BR
Citrullination of Amyloid- Peptides in Alzheimer's Disease.
ACS Chem Neurosci Volume: 12 Page(s): 3719 - 3732
10/06/2021 Authors: Mukherjee S; Perez KA; Dubois C; Nisbet RM; Li Q-X; Varghese S; Jin L; Birchall I; Streltsov VA; Vella LJ
Quantification of metallothionein-III in brain tissues using liquid chromatography tandem mass spectrometry.
Anal Biochem Volume: 630 Page(s): 114326
10/01/2021 Authors: Gunn AP; McLean CA; Crouch PJ; Roberts BR
Erratum to: "Acute phase markers in CSF reveal inflammatory changes in Alzheimer's disease that intersect with pathology, APOE 4, sex and age" [Prog. Neurobiol. 198 (2021) 101904].
Prog Neurobiol Volume: 204 Page(s): 102071
09/01/2021 Authors: Ayton S; Janelidze S; Roberts B; Palmqvist S; Kalinowski P; Diouf I; Belaidi AA; Stomrud E; Bush AI; Hansson
GH18 endo--N-acetylglucosaminidases use distinct mechanisms to process hybrid-type N-linked glycans.
J Biol Chem Volume: 297 Page(s): 101011
08/01/2021 Authors: Trastoy B; Du JJ; Li C; Garca-Alija M; Klontz EH; Roberts BR; Donahue TC; Wang L-X; Sundberg EJ; Guerin ME
Thioesterase superfamily member 1 undergoes stimulus-coupled conformational reorganization to regulate metabolism in mice.
Nat Commun Volume: 12 Page(s): 3493
06/09/2021 Authors: Li Y; Imai N; Nicholls HT; Roberts BR; Goyal S; Krisko TI; Ang L-H; Tillman MC; Roberts AM; Baqai M
Increased glutaminyl cyclase activity in brains of Alzheimer's disease individuals.
J Neurochem Volume: 156 Page(s): 979 - 987
03/01/2021 Authors: Gunn AP; Wong BX; McLean C; Fowler C; Barnard PJ; Duce JA; Roberts BR; AIBL Research Group
Acute phase markers in CSF reveal inflammatory changes in Alzheimer's disease that intersect with pathology, APOE 4, sex and age.
Prog Neurobiol Volume: 198 Page(s): 101904
03/01/2021 Authors: Ayton S; Janelidze S; Roberts B; Palmqvist S; Kalinowski P; Diouf I; Belaidi AA; Stomrud E; Bush AI; Hansson O
Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer's disease.
Nat Commun Volume: 12 Page(s): 721
02/01/2021 Authors: Roe JM; Vidal-Pieiro D; Srensen ; Brandmaier AM; Dzel S; Gonzalez HA; Kievit RA; Knights E; Khn S; Lindenberger U
Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content.
J Neurosci Volume: 41 Page(s): 215 - 233
01/13/2021 Authors: Hartwig C; Mndez GM; Bhattacharjee S; Vrailas-Mortimer AD; Zlatic SA; Freeman AAH; Gokhale A; Concilli M; Werner E; Sapp Savas C
Utilizing Ion Mobility-Mass Spectrometry to Investigate the Unfolding Pathway of Cu/Zn Superoxide Dismutase.
Front Chem Volume: 9 Page(s): 614595
01/01/2021 Authors: Butler KE; Takinami Y; Rainczuk A; Baker ES; Roberts BR
Quantification of N-terminal amyloid- isoforms reveals isomers are the most abundant form of the amyloid- peptide in sporadic Alzheimer's disease.
Brain Commun Volume: 3 Page(s): fcab028
01/01/2021 Authors: Mukherjee S; Perez KA; Lago LC; Klatt S; McLean CA; Birchall IE; Barnham KJ; Masters CL; Roberts BR
2020
Cadmium stress dictates central carbon flux and alters membrane composition in Streptococcus pneumoniae.
Commun Biol Volume: 3 Page(s): 694
11/19/2020 Authors: Neville SL; Eijkelkamp BA; Lothian A; Paton JC; Roberts BR; Rosch JW; McDevitt CA
Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture.
Nat Commun Volume: 11 Page(s): 4799
09/23/2020 Authors: Zhang Q; Sidorenko J; Couvy-Duchesne B; Marioni RE; Wright MJ; Goate AM; Marcora E; Huang K-L; Porter T; Laws SM
PrPSc Oligomerization Appears Dynamic, Quickly Engendering Inherent M1000 Acute Synaptotoxicity.
Biophys J Volume: 119 Page(s): 128 - 141
07/07/2020 Authors: Foliaki ST; Lewis V; Islam AMT; Senesi M; Finkelstein DI; Ellett LJ; Lawson VA; Adlard PA; Roberts BR; Collins SJ
Choice of mobile phase: Implications for size exclusion chromatography-inductively coupled plasma-mass spectrometry analyses of copper, zinc and iron metalloproteins.
J Chromatogr A Volume: 1616 Page(s): 460806
04/12/2020 Authors: Lago L; Thomas ORB; Roberts BR
Human glutaredoxin-1 can transfer copper to isolated metal binding domains of the P1B-type ATPase, ATP7B.
Sci Rep Volume: 10 Page(s): 4157
03/05/2020 Authors: Maghool S; Fontaine SL; Roberts BR; Kwan AH; Maher MJ
In situ 3D visualization of biomineralization matrix proteins.
J Struct Biol Volume: 209 Page(s): 107448
03/01/2020 Authors: Thomas ORB; Richards KL; Petrou S; Roberts BR; Swearer SE
Optimizing red blood cell protein extraction for biomarker quantitation with mass spectrometry.
Anal Bioanal Chem Volume: 412 Page(s): 1879 - 1892
03/01/2020 Authors: Klatt S; Roberts A; Lothian A; Masters CL; Cappai R; Fowler C; Roberts BR
Regional iron distribution and soluble ferroprotein profiles in the healthy human brain.
Prog Neurobiol Volume: 186 Page(s): 101744
03/01/2020 Authors: McAllum EJ; Hare DJ; Volitakis I; McLean CA; Bush AI; Finkelstein DI; Roberts BR
Characterising the brain metalloproteome in Down syndrome patients with concomitant Alzheimer's pathology.
Metallomics Volume: 12 Page(s): 114 - 132
01/29/2020 Authors: Malakooti N; Roberts B; Pritchard MA; Volitakis I; Kim RC; Lott IT; McLean CA; Finkelstein DI; Adlard PA
Zinc Transporter-3 Knockout Mice Demonstrate Age-Dependent Alterations in the Metalloproteome.
Int J Mol Sci Volume: 21
01/28/2020 Authors: Hancock SM; Portbury SD; Gunn AP; Roberts BR; Bush AI; Adlard PA
2019
Expanding beyond ICP-MS to better understand selenium biochemistry.
Metallomics Volume: 11 Page(s): 1974 - 1983
12/11/2019 Authors: Cardoso BR; Ganio K; Roberts BR
Greater Circulating Copper Concentrations and Copper/Zinc Ratios are Associated with Lower Psychological Distress, But Not Cognitive Performance, in a Sample of Australian Older Adults.
Nutrients Volume: 11
10/17/2019 Authors: Mravunac M; Szymlek-Gay EA; Daly RM; Roberts BR; Formica M; Gianoudis J; O'Connell SL; Nowson CA; Cardoso BR
Establishing Signature Fragments for Identification and Sequencing of Dityrosine Cross-Linked Peptides Using Ultraviolet Photodissociation Mass Spectrometry.
Anal Chem Volume: 91 Page(s): 12129 - 12133
10/01/2019 Authors: Mukherjee S; Fang M; Kok WM; Kapp EA; Thombare VJ; Huguet R; Hutton CA; Reid GE; Roberts BR
Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc.
PLoS Pathog Volume: 15 Page(s): e1007712
04/01/2019 Authors: Foliaki ST; Lewis V; Islam AMT; Ellett LJ; Senesi M; Finkelstein DI; Roberts B; Lawson VA; Adlard PA; Collins SJ
Characterization of the metal status of natively purified alpha-synuclein from human blood, brain tissue, or recombinant sources using size exclusion ICP-MS reveals no significant binding of Cu, Fe or Zn.
Metallomics Volume: 11 Page(s): 128 - 140
01/23/2019 Authors: Lothian A; Lago L; Mukherjee S; Connor AR; Fowler C; McLean CA; Horne M; Masters CL; Cappai R; Roberts BR
The inner ear proteome of fish.
FEBS J Volume: 286 Page(s): 66 - 81
01/01/2019 Authors: Thomas ORB; Swearer SE; Kapp EA; Peng P; Tonkin-Hill GQ; Papenfuss A; Roberts A; Bernard P; Roberts BR
Supranutritional Sodium Selenate Supplementation Delivers Selenium to the Central Nervous System: Results from a Randomized Controlled Pilot Trial in Alzheimer's Disease.
Neurotherapeutics Volume: 16 Page(s): 192 - 202
01/01/2019 Authors: Cardoso BR; Roberts BR; Malpas CB; Vivash L; Genc S; Saling MM; Desmond P; Steward C; Hicks RJ; Callahan J
Copper isotope compositions of superoxide dismutase and metallothionein from post-mortem human frontal cortex
Inorganics Volume: 7
01/01/2019 Authors: Larner F; McLean CA; Halliday AN; Roberts BR
2018
Selenium Status Is Not Associated with Cognitive Performance: A Cross-Sectional Study in 154 Older Australian Adults.
Nutrients Volume: 10
12/01/2018 Authors: Cardoso BR; Szymlek-Gay EA; Roberts BR; Formica M; Gianoudis J; O'Connell S; Nowson CA; Daly RM
Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice.
Neurotherapeutics Volume: 15 Page(s): 1055 - 1062
10/01/2018 Authors: Belaidi AA; Gunn AP; Wong BX; Ayton S; Appukuttan AT; Roberts BR; Duce JA; Bush AI
Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species.
PLoS Pathog Volume: 14 Page(s): e1007214
08/01/2018 Authors: Foliaki ST; Lewis V; Finkelstein DI; Lawson V; Coleman HA; Senesi M; Islam AMT; Chen F; Sarros S; Roberts B
DELINEATING THE NEUROPROTECTIVE ROLE OF THE AMYLOID PRECURSOR PROTEIN FAMILY IN TRAUMATIC BRAIN INJURY
Volume: 35 Page(s): A57 - A57
08/01/2018 Authors: Cappai R; Inampudi C; Corrigan F; Lam L; Roberts B; Thornton E; Vink R; Ciccotosto G; Crack P; Van den Heuvel C
Alzheimer’s Disease: Toward a Quantitative Biological Approach in Describing its Natural History and Underlying Mechanisms
The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms Page(s): 57 - 79
01/01/2018 Authors: Masters CL; Gu B; Laws S; Lim YY; Roberts B; Villemagne VL; Beyreuther K
2017
The influence of the ethane-1,2-diamine ligand on the activity of a monofunctional platinum complex.
J Inorg Biochem Volume: 177 Page(s): 328 - 334
12/01/2017 Authors: Graziotto ME; Akerfeldt MC; Gunn AP; Yang K; Somerville MV; Coleman NV; Roberts BR; Hambley TW; New EJ
A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of -amyloid load in an AD cohort.
Sci Rep Volume: 7 Page(s): 14057
10/25/2017 Authors: Pedrini S; Gupta VB; Hone E; Doecke J; O'Bryant S; James I; Bush AI; Rowe CC; Villemagne VL; Ames D
Subcellular compartmentalisation of copper, iron, manganese, and zinc in the Parkinson's disease brain.
Metallomics Volume: 9 Page(s): 1447 - 1455
10/18/2017 Authors: Genoud S; Roberts BR; Gunn AP; Halliday GM; Lewis SJG; Ball HJ; Hare DJ; Double KL
The APOE 4 Allele Is Associated with Lower Selenium Levels in the Brain: Implications for Alzheimer's Disease.
ACS Chem Neurosci Volume: 8 Page(s): 1459 - 1464
07/19/2017 Authors: R Cardoso B; Hare DJ; Lind M; McLean CA; Volitakis I; Laws SM; Masters CL; Bush AI; Roberts BR
Characterization and Identification of Dityrosine Cross-Linked Peptides Using Tandem Mass Spectrometry.
Anal Chem Volume: 89 Page(s): 6136 - 6145
06/06/2017 Authors: Mukherjee S; Kapp EA; Lothian A; Roberts AM; Vasil'ev YV; Boughton BA; Barnham KJ; Kok WM; Hutton CA; Masters CL
Molecular Aspects of a Robust Assay for Ferroxidase Function of Ceruloplasmin.
Inorg Chem Volume: 56 Page(s): 5275 - 5284
05/01/2017 Authors: Cortes L; Roberts BR; Wedd AG; Xiao Z
Biochemically-defined pools of amyloid- in sporadic Alzheimer's disease: correlation with amyloid PET.
Brain Volume: 140 Page(s): 1486 - 1498
05/01/2017 Authors: Roberts BR; Lind M; Wagen AZ; Rembach A; Frugier T; Li Q-X; Ryan TM; McLean CA; Doecke JD; Rowe CC
Direct determination of zinc in plasma by graphite furnace atomic absorption spectrometry using palladium/magnesium and EDTA matrix modification with high temperature pyrolysis
Journal of Analytical Atomic Spectrometry Volume: 32 Page(s): 843 - 847
04/01/2017 Authors: Stevens BJ; Hare DJ; Volitakis I; Cherny RA; Roberts BR
Trace element-protein interactions in endolymph from the inner ear of fish: implications for environmental reconstructions using fish otolith chemistry.
Metallomics Volume: 9 Page(s): 239 - 249
03/22/2017 Authors: Thomas ORB; Ganio K; Roberts BR; Swearer SE
Glutathione peroxidase 4: a new player in neurodegeneration?
Mol Psychiatry Volume: 22 Page(s): 328 - 335
03/01/2017 Authors: Cardoso BR; Hare DJ; Bush AI; Roberts BR
CuII(atsm) improves the neurological phenotype and survival of SOD1G93A mice and selectively increases enzymatically active SOD1 in the spinal cord.
Sci Rep Volume: 7 Page(s): 42292
02/13/2017 Authors: Hilton JB; Mercer SW; Lim NKH; Faux NG; Buncic G; Beckman JS; Roberts BR; Donnelly PS; White AR; Crouch PJ
Selenium Levels in Serum, Red Blood Cells, and Cerebrospinal Fluid of Alzheimer's Disease Patients: A Report from the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL).
J Alzheimers Dis Volume: 57 Page(s): 183 - 193
01/01/2017 Authors: Cardoso BR; Hare DJ; Bush AI; Li Q-X; Fowler CJ; Masters CL; Martins RN; Ganio K; Lothian A; Mukherjee S
Analysis of trace elements and metalloproteins in fractionated human brain samples using size exclusion inductively coupled mass spectrometry
Neuromethods Volume: 124 Page(s): 119 - 125
01/01/2017 Authors: Gunn AP; Roberts BR