Publications

• Serotonergic-dependent effects of exercise and elevated stress hormone on small non-coding RNA transcriptomics and proteomics in a mouse model of affective disorders.
  Neuropharmacology Volume: 265 Page(s): 110240
  03/01/2025 Authors: Kuznetsova M; Wilson C; Cheng L; Pang T; Li S; Roberts BR; Lago LC; Tran H; Hill AF; Hannan AJ
• Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration.
  Mol Biol Cell Volume: 36 Page(s): ar33
  03/01/2025 Authors: Lane AR; Scher NE; Bhattacharjee S; Zlatic SA; Roberts AM; Gokhale A; Singleton KS; Duong DM; McKenna M; Liu WL
• Mitochondrially Transcribed dsRNA Mediates Manganese-induced Neuroinflammation.
  bioRxiv
  02/20/2025 Authors: Gokhale A; Mendez-Vazquez H; Sampson MM; Moctezuma FGR; Harbuzariu A; Sing A; Zlatic SA; Roberts AM; Prajapati M; Roberts BR
• Stratifying risk of Alzheimer's disease in healthy middle-aged individuals with machine learning.
  Brain Commun Volume: 7 Page(s): fcaf121
  01/01/2025 Authors: Tandon R; Zhao L; Watson CM; Sarkar N; Elmor M; Heilman C; Sanders K; Hales CM; Yang H; Loring DW
• Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration.
  
  11/18/2024 Authors: Lane AR; Scher NE; Bhattacharjee S; Zlatic SA; Roberts AM; Gokhale A; Singleton KS; Duong DM; McKenna M; Liu WL
• Heparin-enriched plasma proteome is significantly altered in Alzheimer's disease.
  Mol Neurodegener Volume: 19 Page(s): 67
  10/08/2024 Authors: Guo Q; Ping L; Dammer EB; Duong DM; Yin L; Xu K; Shantaraman A; Fox EJ; Golde TE; Johnson ECB
• Integrated elemental analysis supports targeting copper perturbations as a therapeutic strategy in multiple sclerosis.
  Neurotherapeutics Volume: 21 Page(s): e00432
  09/01/2024 Authors: Hilton JBW; Kysenius K; Liddell JR; Mercer SW; Rautengarten C; Hare DJ; Buncic G; Paul B; Murray SS; McLean CA
• Deciphering ApoE Genotype-Driven Proteomic and Lipidomic Alterations in Alzheimer's Disease Across Distinct Brain Regions.
  J Proteome Res Volume: 23 Page(s): 2970 - 2985
  08/02/2024 Authors: Odenkirk MT; Zheng X; Kyle JE; Stratton KG; Nicora CD; Bloodsworth KJ; Mclean CA; Masters CL; Monroe ME; Doecke JD
• Evidence for disrupted copper availability in human spinal cord supports CuII(atsm) as a treatment option for sporadic cases of ALS.
  Sci Rep Volume: 14 Page(s): 5929
  03/11/2024 Authors: Hilton JBW; Kysenius K; Liddell JR; Mercer SW; Paul B; Beckman JS; McLean CA; White AR; Donnelly PS; Bush AI
• Heparin-enriched plasma proteome is significantly altered in Alzheimer's Disease.
  Res Sq
  02/23/2024 Authors: Guo Q; Ping L; Dammer EB; Yin L; Xu K; Shantaraman A; Fox EJ; Golde TE; Johnson ECB; Roberts BR
• Microglial ferroptotic stress causes non-cell autonomous neuronal death.
  Mol Neurodegener Volume: 19 Page(s): 14
  02/05/2024 Authors: Liddell JR; Hilton JBW; Kysenius K; Billings JL; Nikseresht S; McInnes LE; Hare DJ; Paul B; Mercer SW; Belaidi AA
• The Association of Alzheimer's Disease-Related Blood-Based Biomarkers with Cognitive Screening Test Performance in the Congolese Population in Kinshasa.
  J Alzheimers Dis Volume: 97 Page(s): 1353 - 1363
  01/01/2024 Authors: Schwinne M; Alonso A; Roberts BR; Hickle S; Verberk IMW; Epenge E; Gikelekele G; Tsengele N; Kavugho I; Mampunza S
• The Association of Alzheimer's Disease-related Blood-based Biomarkers with Cognitive Screening Test Performance in the Congolese Population in Kinshasa.
  medRxiv
  10/31/2023 Authors: Schwinne M; Alonso A; Roberts BR; Hickle S; Verberk IM; Epenge E; Gikelekele G; Tsengele N; Kavugho I; Mampunza S
• A protein panel in cerebrospinal fluid for diagnostic and predictive assessment of Alzheimer's disease.
  Sci Transl Med Volume: 15 Page(s): eadg4122
  09/06/2023 Authors: Haque R; Watson CM; Liu J; Carter EK; Duong DM; Lah JJ; Wingo AP; Roberts BR; Johnson ECB; Saykin AJ
• Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease.
  Nat Med Volume: 29 Page(s): 1979 - 1988
  08/01/2023 Authors: Johnson ECB; Bian S; Haque RU; Carter EK; Watson CM; Gordon BA; Ping L; Duong DM; Epstein MP; McDade E
• Quantitative proteomics of cerebrospinal fluid from African Americans and Caucasians reveals shared and divergent changes in Alzheimer's disease.
  Mol Neurodegener Volume: 18 Page(s): 48
  07/19/2023 Authors: Modeste ES; Ping L; Watson CM; Duong DM; Dammer EB; Johnson ECB; Roberts BR; Lah JJ; Levey AI; Seyfried NT
• APOE expression and secretion are modulated by mitochondrial dysfunction.
  Elife Volume: 12
  05/12/2023 Authors: Wynne ME; Ogunbona O; Lane AR; Gokhale A; Zlatic SA; Xu C; Wen Z; Duong DM; Rayaprolu S; Ivanova A
• Quantitative Mass Spectrometry Analysis of Cerebrospinal Fluid Protein Biomarkers in Alzheimer's Disease.
  Sci Data Volume: 10 Page(s): 261
  05/09/2023 Authors: Watson CM; Dammer EB; Ping L; Duong DM; Modeste E; Carter EK; Johnson ECB; Levey AI; Lah JJ; Roberts BR
• Multiplatform analyses reveal distinct drivers of systemic pathogenesis in adult versus pediatric severe acute COVID-19.
  Nat Commun Volume: 14 Page(s): 1638
  04/04/2023 Authors: Druzak S; Iffrig E; Roberts BR; Zhang T; Fibben KS; Sakurai Y; Verkerke HP; Rostad CA; Chahroudi A; Schneider F
• CSF ferritin in the clinicopathological progression of Alzheimer's disease and associations with APOE and inflammation biomarkers.
  J Neurol Neurosurg Psychiatry Volume: 94 Page(s): 211 - 219
  03/01/2023 Authors: Ayton S; Janelidze S; Kalinowski P; Palmqvist S; Belaidi AA; Stomrud E; Roberts A; Roberts B; Hansson O; Bush AI
• Predictors of Cognitive Decline in Healthy Middle-Aged Individuals with Asymptomatic Alzheimer's Disease.
  Res Sq
  02/28/2023 Authors: Tandon R; Zhao L; Watson CM; Elmor M; Heilman C; Sanders K; Hales CM; Yang H; Loring DW; Goldstein FC
• Quantitative proteomics of tau and A in detergent fractions from Alzheimer's disease brains.
  J Neurochem Volume: 164 Page(s): 529 - 552
  02/01/2023 Authors: Mukherjee S; Dubois C; Perez K; Varghese S; Birchall IE; Leckey M; Davydova N; McLean C; Nisbet RM; Roberts BR
• Discovery of a Missense Mutation (Q222K) of the APOE Gene from the Australian Imaging, Biomarker and Lifestyle Study.
  J Alzheimers Dis Rep Volume: 7 Page(s): 165 - 172
  01/01/2023 Authors: Roberts BR; Laffoon SB; Roberts AM; Porter T; Fowler C; Masters CL; Dratz EA; Laws SM
• Mass Spectrometry-Based Methods to Determine the Substrate Specificities and Kinetics of N-Linked Glycan Hydrolysis by Endo--N-Acetylglucosaminidases.
  Methods Mol Biol Volume: 2674 Page(s): 147 - 167
  01/01/2023 Authors: Du JJ; Sastre D; Trastoy B; Roberts B; Deredge D; Klontz EH; Flowers MW; Sultana N; Guerin ME; Sundberg EJ
• Association of plasma biomarkers with cognitive function in persons with dementia and cognitively healthy in the Democratic Republic of Congo.
  Alzheimers Dement (Amst) Volume: 15 Page(s): e12496
  01/01/2023 Authors: Ikanga J; Patel SS; Roberts BR; Schwinne M; Hickle S; Verberk IMW; Epenge E; Gikelekele G; Tshengele N; Kavugho I
• From Blue to Gray: Inflammation, Aging and Neurodegeneration in Depression
  Volume: 47 Page(s): 246 - 247
  12/01/2022 Authors: Haroon E; Beltran D; Chen X; Wommack E; Roberts B; Qiu D; Goldstein F; Treadway M; Felger J; Miller A
• The mitochondrial RNA granule modulates manganese-dependent cell toxicity.
  Mol Biol Cell Volume: 33 Page(s): ar108
  10/01/2022 Authors: Werner E; Gokhale A; Ackert M; Xu C; Wen Z; Roberts AM; Roberts BR; Vrailas-Mortimer A; Crocker A; Faundez V
• Enhanced ion mobility resolution of Abeta isomers from human brain using high-resolution demultiplexing software.
  Anal Bioanal Chem Volume: 414 Page(s): 5683 - 5693
  07/01/2022 Authors: Mukherjee S; Fjeldsted JC; Masters CL; Roberts BR
• Sulfur- and phosphorus-standardized metal quantification of biological specimens using inductively coupled plasma mass spectrometry.
  STAR Protoc Volume: 3 Page(s): 101334
  06/17/2022 Authors: Lane A; Gokhale A; Werner E; Roberts A; Freeman A; Roberts B; Faundez V
• The Neuroinflammatory Acute Phase Response in Parkinsonian-Related Disorders.
  Mov Disord Volume: 37 Page(s): 993 - 1003
  05/01/2022 Authors: Ayton S; Hall S; Janelidze S; Kalinowski P; Palmqvist S; Belaidi AA; Roberts B; Roberts A; Stomrud E; Bush AI
• Quantitative Phosphoproteomics Reveals Extensive Protein Phosphorylation Dysregulation in the Cerebral Cortex of Huntington's Disease Mice Prior to Onset of Symptoms.
  Mol Neurobiol Volume: 59 Page(s): 2456 - 2471
  04/01/2022 Authors: Mees I; Tran H; Roberts A; Lago L; Li S; Roberts BR; Hannan AJ; Renoir T
• Author Correction: Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer's disease.
  Nat Commun Volume: 13 Page(s): 834
  02/07/2022 Authors: Roe JM; Vidal-Pieiro D; Srensen ; Brandmaier AM; Dzel S; Gonzalez HA; Kievit RA; Knights E; Khn S; Lindenberger U
• Analysis of plasma proteins using 2D gels and novel fluorescent probes: in search of blood based biomarkers for Alzheimer's disease.
  Proteome Sci Volume: 20 Page(s): 2
  01/26/2022 Authors: Laffoon SB; Doecke JD; Roberts AM; Vance JA; Reeves BD; Pertile KK; Rumble RL; Fowler CJ; Trounson B; Ames D
• Semi-quantitative methods for multi-site deglycosylation events
  Volume: 31 Page(s): 1733 - 1734
  12/01/2021 Authors: Du J; Roberts B; Sundberg E; Deredge D
• Antisense oligonucleotide therapy reduces seizures and extends life span in an SCN2A gain-of-function epilepsy model.
  J Clin Invest Volume: 131
  12/01/2021 Authors: Li M; Jancovski N; Jafar-Nejad P; Burbano LE; Rollo B; Richards K; Drew L; Sedo A; Heighway J; Pachernegg S
• Differential protein expression due to Se deficiency and Se toxicity in rat liver.
  J Nutr Biochem Volume: 98 Page(s): 108831
  12/01/2021 Authors: Cardoso BR; Lago L; Dordevic AL; Kapp EA; Raines AM; Sunde RA; Roberts BR
• A six-metabolite panel as potential blood-based biomarkers for Parkinson's disease.
  NPJ Parkinsons Dis Volume: 7 Page(s): 94
  10/14/2021 Authors: Klatt S; Doecke JD; Roberts A; Boughton BA; Masters CL; Horne M; Roberts BR
• Citrullination of Amyloid- Peptides in Alzheimer's Disease.
  ACS Chem Neurosci Volume: 12 Page(s): 3719 - 3732
  10/06/2021 Authors: Mukherjee S; Perez KA; Dubois C; Nisbet RM; Li Q-X; Varghese S; Jin L; Birchall I; Streltsov VA; Vella LJ
• Quantification of metallothionein-III in brain tissues using liquid chromatography tandem mass spectrometry.
  Anal Biochem Volume: 630 Page(s): 114326
  10/01/2021 Authors: Gunn AP; McLean CA; Crouch PJ; Roberts BR
• Erratum to: "Acute phase markers in CSF reveal inflammatory changes in Alzheimer's disease that intersect with pathology, APOE 4, sex and age" [Prog. Neurobiol. 198 (2021) 101904].
  Prog Neurobiol Volume: 204 Page(s): 102071
  09/01/2021 Authors: Ayton S; Janelidze S; Roberts B; Palmqvist S; Kalinowski P; Diouf I; Belaidi AA; Stomrud E; Bush AI; Hansson O
• GH18 endo--N-acetylglucosaminidases use distinct mechanisms to process hybrid-type N-linked glycans.
  J Biol Chem Volume: 297 Page(s): 101011
  08/01/2021 Authors: Trastoy B; Du JJ; Li C; Garca-Alija M; Klontz EH; Roberts BR; Donahue TC; Wang L-X; Sundberg EJ; Guerin ME
• Thioesterase superfamily member 1 undergoes stimulus-coupled conformational reorganization to regulate metabolism in mice.
  Nat Commun Volume: 12 Page(s): 3493
  06/09/2021 Authors: Li Y; Imai N; Nicholls HT; Roberts BR; Goyal S; Krisko TI; Ang L-H; Tillman MC; Roberts AM; Baqai M
• Acute phase markers in CSF reveal inflammatory changes in Alzheimer's disease that intersect with pathology, APOE 4, sex and age.
  Prog Neurobiol Volume: 198 Page(s): 101904
  03/01/2021 Authors: Ayton S; Janelidze S; Roberts B; Palmqvist S; Kalinowski P; Diouf I; Belaidi AA; Stomrud E; Bush AI; Hansson O
• Increased glutaminyl cyclase activity in brains of Alzheimer's disease individuals.
  J Neurochem Volume: 156 Page(s): 979 - 987
  03/01/2021 Authors: Gunn AP; Wong BX; McLean C; Fowler C; Barnard PJ; Duce JA; Roberts BR; AIBL Research Group
• Asymmetric thinning of the cerebral cortex across the adult lifespan is accelerated in Alzheimer's disease.
  Nat Commun Volume: 12 Page(s): 721
  02/01/2021 Authors: Roe JM; Vidal-Pieiro D; Srensen ; Brandmaier AM; Dzel S; Gonzalez HA; Kievit RA; Knights E; Khn S; Lindenberger U
• Golgi-Dependent Copper Homeostasis Sustains Synaptic Development and Mitochondrial Content.
  J Neurosci Volume: 41 Page(s): 215 - 233
  01/13/2021 Authors: Hartwig C; Mndez GM; Bhattacharjee S; Vrailas-Mortimer AD; Zlatic SA; Freeman AAH; Gokhale A; Concilli M; Werner E; Sapp Savas C
• Utilizing Ion Mobility-Mass Spectrometry to Investigate the Unfolding Pathway of Cu/Zn Superoxide Dismutase.
  Front Chem Volume: 9 Page(s): 614595
  01/01/2021 Authors: Butler KE; Takinami Y; Rainczuk A; Baker ES; Roberts BR
• Quantification of N-terminal amyloid- isoforms reveals isomers are the most abundant form of the amyloid- peptide in sporadic Alzheimer's disease.
  Brain Commun Volume: 3 Page(s): fcab028
  01/01/2021 Authors: Mukherjee S; Perez KA; Lago LC; Klatt S; McLean CA; Birchall IE; Barnham KJ; Masters CL; Roberts BR
• Cadmium stress dictates central carbon flux and alters membrane composition in Streptococcus pneumoniae.
  Commun Biol Volume: 3 Page(s): 694
  11/19/2020 Authors: Neville SL; Eijkelkamp BA; Lothian A; Paton JC; Roberts BR; Rosch JW; McDevitt CA
• Risk prediction of late-onset Alzheimer's disease implies an oligogenic architecture.
  Nat Commun Volume: 11 Page(s): 4799
  09/23/2020 Authors: Zhang Q; Sidorenko J; Couvy-Duchesne B; Marioni RE; Wright MJ; Goate AM; Marcora E; Huang K-L; Porter T; Laws SM
• PrPSc Oligomerization Appears Dynamic, Quickly Engendering Inherent M1000 Acute Synaptotoxicity.
  Biophys J Volume: 119 Page(s): 128 - 141
  07/07/2020 Authors: Foliaki ST; Lewis V; Islam AMT; Senesi M; Finkelstein DI; Ellett LJ; Lawson VA; Adlard PA; Roberts BR; Collins SJ
• Choice of mobile phase: Implications for size exclusion chromatography-inductively coupled plasma-mass spectrometry analyses of copper, zinc and iron metalloproteins.
  J Chromatogr A Volume: 1616 Page(s): 460806
  04/12/2020 Authors: Lago L; Thomas ORB; Roberts BR
• Human glutaredoxin-1 can transfer copper to isolated metal binding domains of the P1B-type ATPase, ATP7B.
  Sci Rep Volume: 10 Page(s): 4157
  03/05/2020 Authors: Maghool S; Fontaine SL; Roberts BR; Kwan AH; Maher MJ
• In situ 3D visualization of biomineralization matrix proteins.
  J Struct Biol Volume: 209 Page(s): 107448
  03/01/2020 Authors: Thomas ORB; Richards KL; Petrou S; Roberts BR; Swearer SE
• Optimizing red blood cell protein extraction for biomarker quantitation with mass spectrometry.
  Anal Bioanal Chem Volume: 412 Page(s): 1879 - 1892
  03/01/2020 Authors: Klatt S; Roberts A; Lothian A; Masters CL; Cappai R; Fowler C; Roberts BR
• Regional iron distribution and soluble ferroprotein profiles in the healthy human brain.
  Prog Neurobiol Volume: 186 Page(s): 101744
  03/01/2020 Authors: McAllum EJ; Hare DJ; Volitakis I; McLean CA; Bush AI; Finkelstein DI; Roberts BR
• Characterising the brain metalloproteome in Down syndrome patients with concomitant Alzheimer's pathology.
  Metallomics Volume: 12 Page(s): 114 - 132
  01/29/2020 Authors: Malakooti N; Roberts B; Pritchard MA; Volitakis I; Kim RC; Lott IT; McLean CA; Finkelstein DI; Adlard PA
• Zinc Transporter-3 Knockout Mice Demonstrate Age-Dependent Alterations in the Metalloproteome.
  Int J Mol Sci Volume: 21
  01/28/2020 Authors: Hancock SM; Portbury SD; Gunn AP; Roberts BR; Bush AI; Adlard PA
• Expanding beyond ICP-MS to better understand selenium biochemistry.
  Metallomics Volume: 11 Page(s): 1974 - 1983
  12/11/2019 Authors: Cardoso BR; Ganio K; Roberts BR
• Greater Circulating Copper Concentrations and Copper/Zinc Ratios are Associated with Lower Psychological Distress, But Not Cognitive Performance, in a Sample of Australian Older Adults.
  Nutrients Volume: 11
  10/17/2019 Authors: Mravunac M; Szymlek-Gay EA; Daly RM; Roberts BR; Formica M; Gianoudis J; O'Connell SL; Nowson CA; Cardoso BR
• Establishing Signature Fragments for Identification and Sequencing of Dityrosine Cross-Linked Peptides Using Ultraviolet Photodissociation Mass Spectrometry.
  Anal Chem Volume: 91 Page(s): 12129 - 12133
  10/01/2019 Authors: Mukherjee S; Fang M; Kok WM; Kapp EA; Thombare VJ; Huguet R; Hutton CA; Reid GE; Roberts BR
• Early existence and biochemical evolution characterise acutely synaptotoxic PrPSc.
  PLoS Pathog Volume: 15 Page(s): e1007712
  04/01/2019 Authors: Foliaki ST; Lewis V; Islam AMT; Ellett LJ; Senesi M; Finkelstein DI; Roberts B; Lawson VA; Adlard PA; Collins SJ
• Characterization of the metal status of natively purified alpha-synuclein from human blood, brain tissue, or recombinant sources using size exclusion ICP-MS reveals no significant binding of Cu, Fe or Zn.
  Metallomics Volume: 11 Page(s): 128 - 140
  01/23/2019 Authors: Lothian A; Lago L; Mukherjee S; Connor AR; Fowler C; McLean CA; Horne M; Masters CL; Cappai R; Roberts BR
• The inner ear proteome of fish.
  FEBS J Volume: 286 Page(s): 66 - 81
  01/01/2019 Authors: Thomas ORB; Swearer SE; Kapp EA; Peng P; Tonkin-Hill GQ; Papenfuss A; Roberts A; Bernard P; Roberts BR
• Supranutritional Sodium Selenate Supplementation Delivers Selenium to the Central Nervous System: Results from a Randomized Controlled Pilot Trial in Alzheimer's Disease.
  Neurotherapeutics Volume: 16 Page(s): 192 - 202
  01/01/2019 Authors: Cardoso BR; Roberts BR; Malpas CB; Vivash L; Genc S; Saling MM; Desmond P; Steward C; Hicks RJ; Callahan J
• Selenium Status Is Not Associated with Cognitive Performance: A Cross-Sectional Study in 154 Older Australian Adults.
  Nutrients Volume: 10
  12/01/2018 Authors: Cardoso BR; Szymlek-Gay EA; Roberts BR; Formica M; Gianoudis J; O'Connell S; Nowson CA; Daly RM
• Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice.
  Neurotherapeutics Volume: 15 Page(s): 1055 - 1062
  10/01/2018 Authors: Belaidi AA; Gunn AP; Wong BX; Ayton S; Appukuttan AT; Roberts BR; Duce JA; Bush AI
• Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species.
  PLoS Pathog Volume: 14 Page(s): e1007214
  08/01/2018 Authors: Foliaki ST; Lewis V; Finkelstein DI; Lawson V; Coleman HA; Senesi M; Islam AMT; Chen F; Sarros S; Roberts B
• DELINEATING THE NEUROPROTECTIVE ROLE OF THE AMYLOID PRECURSOR PROTEIN FAMILY IN TRAUMATIC BRAIN INJURY
  Volume: 35 Page(s): A57 - A57
  08/01/2018 Authors: Cappai R; Inampudi C; Corrigan F; Lam L; Roberts B; Thornton E; Vink R; Ciccotosto G; Crack P; Van den Heuvel C
• The influence of the ethane-1,2-diamine ligand on the activity of a monofunctional platinum complex.
  J Inorg Biochem Volume: 177 Page(s): 328 - 334
  12/01/2017 Authors: Graziotto ME; Akerfeldt MC; Gunn AP; Yang K; Somerville MV; Coleman NV; Roberts BR; Hambley TW; New EJ
• A blood-based biomarker panel indicates IL-10 and IL-12/23p40 are jointly associated as predictors of -amyloid load in an AD cohort.
  Sci Rep Volume: 7 Page(s): 14057
  10/25/2017 Authors: Pedrini S; Gupta VB; Hone E; Doecke J; O'Bryant S; James I; Bush AI; Rowe CC; Villemagne VL; Ames D
• Subcellular compartmentalisation of copper, iron, manganese, and zinc in the Parkinson's disease brain.
  Metallomics Volume: 9 Page(s): 1447 - 1455
  10/18/2017 Authors: Genoud S; Roberts BR; Gunn AP; Halliday GM; Lewis SJG; Ball HJ; Hare DJ; Double KL
• The APOE 4 Allele Is Associated with Lower Selenium Levels in the Brain: Implications for Alzheimer's Disease.
  ACS Chem Neurosci Volume: 8 Page(s): 1459 - 1464
  07/19/2017 Authors: R Cardoso B; Hare DJ; Lind M; McLean CA; Volitakis I; Laws SM; Masters CL; Bush AI; Roberts BR
• Characterization and Identification of Dityrosine Cross-Linked Peptides Using Tandem Mass Spectrometry.
  Anal Chem Volume: 89 Page(s): 6136 - 6145
  06/06/2017 Authors: Mukherjee S; Kapp EA; Lothian A; Roberts AM; Vasil'ev YV; Boughton BA; Barnham KJ; Kok WM; Hutton CA; Masters CL
• Molecular Aspects of a Robust Assay for Ferroxidase Function of Ceruloplasmin.
  Inorg Chem Volume: 56 Page(s): 5275 - 5284
  05/01/2017 Authors: Cortes L; Roberts BR; Wedd AG; Xiao Z
• Biochemically-defined pools of amyloid- in sporadic Alzheimer's disease: correlation with amyloid PET.
  Brain Volume: 140 Page(s): 1486 - 1498
  05/01/2017 Authors: Roberts BR; Lind M; Wagen AZ; Rembach A; Frugier T; Li Q-X; Ryan TM; McLean CA; Doecke JD; Rowe CC
• Trace element-protein interactions in endolymph from the inner ear of fish: implications for environmental reconstructions using fish otolith chemistry.
  Metallomics Volume: 9 Page(s): 239 - 249
  03/22/2017 Authors: Thomas ORB; Ganio K; Roberts BR; Swearer SE
• Glutathione peroxidase 4: a new player in neurodegeneration?
  Mol Psychiatry Volume: 22 Page(s): 328 - 335
  03/01/2017 Authors: Cardoso BR; Hare DJ; Bush AI; Roberts BR
• CuII(atsm) improves the neurological phenotype and survival of SOD1G93A mice and selectively increases enzymatically active SOD1 in the spinal cord.
  Sci Rep Volume: 7 Page(s): 42292
  02/13/2017 Authors: Hilton JB; Mercer SW; Lim NKH; Faux NG; Buncic G; Beckman JS; Roberts BR; Donnelly PS; White AR; Crouch PJ
• Selenium Levels in Serum, Red Blood Cells, and Cerebrospinal Fluid of Alzheimer's Disease Patients: A Report from the Australian Imaging, Biomarker & Lifestyle Flagship Study of Ageing (AIBL).
  J Alzheimers Dis Volume: 57 Page(s): 183 - 193
  01/01/2017 Authors: Cardoso BR; Hare DJ; Bush AI; Li Q-X; Fowler CJ; Masters CL; Martins RN; Ganio K; Lothian A; Mukherjee S
• Rubidium and potassium levels are altered in Alzheimer's disease brain and blood but not in cerebrospinal fluid.
  Acta Neuropathol Commun Volume: 4 Page(s): 119
  11/14/2016 Authors: Roberts BR; Doecke JD; Rembach A; Yvenes LF; Fowler CJ; McLean CA; Lind M; Volitakis I; Masters CL; Bush AI
• The Neurobiology and Age-Related Prevalence of the 4 Allele of Apolipoprotein E in Alzheimer's Disease Cohorts.
  J Mol Neurosci Volume: 60 Page(s): 316 - 324
  11/01/2016 Authors: Heffernan AL; Chidgey C; Peng P; Masters CL; Roberts BR
• Correction: Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging.
  Chem Sci Volume: 7 Page(s): 6576
  10/01/2016 Authors: Paul B; Hare DJ; Bishop DP; Paton C; Nguyen VT; Cole N; Niedwiecki MM; Andreozzi E; Vais A; Billings JL
• Laser ablation-inductively coupled plasma-mass spectrometry imaging of white and gray matter iron distribution in Alzheimer's disease frontal cortex.
  Neuroimage Volume: 137 Page(s): 124 - 131
  08/15/2016 Authors: Hare DJ; Raven EP; Roberts BR; Bogeski M; Portbury SD; McLean CA; Masters CL; Connor JR; Bush AI; Crouch PJ
• Lead and manganese levels in serum and erythrocytes in Alzheimer's disease and mild cognitive impairment: results from the Australian Imaging, Biomarkers and Lifestyle Flagship Study of Ageing.
  Metallomics Volume: 8 Page(s): 628 - 632
  06/01/2016 Authors: Hare DJ; Faux NG; Roberts BR; Volitakis I; Martins RN; Bush AI
• Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the Copper-Chaperone-for-SOD.
  Neurobiol Dis Volume: 89 Page(s): 1 - 9
  05/01/2016 Authors: Williams JR; Trias E; Beilby PR; Lopez NI; Labut EM; Bradford CS; Roberts BR; McAllum EJ; Crouch PJ; Rhoads TW
• Standards for Quantitative Metalloproteomic Analysis Using Size Exclusion ICP-MS.
  J Vis Exp
  04/13/2016 Authors: Lothian A; Roberts BR
• Accurate biometal quantification per individual Caenorhabditis elegans.
  Analyst Volume: 141 Page(s): 1434 - 1439
  02/21/2016 Authors: Ganio K; James SA; Hare DJ; Roberts BR; McColl G
• Matrix metalloprotease processing of the prion protein
  Volume: 10 Page(s): S41 - S42
  01/01/2016 Authors: Lewis V; Johanssen VA; Roberts BR; Collins SJ
• Profiling changes to natively-bound metals during Caenorhabditis elegans development.
  RSC Adv Volume: 6 Page(s): 113689 - 113693
  01/01/2016 Authors: Hare DJ; Roberts BR; McColl G
• The Emerging Role of Metalloproteomics in Alzheimer's Disease Research.
  Methods Mol Biol Volume: 1303 Page(s): 379 - 389
  01/01/2016 Authors: Hare DJ; Rembach A; Roberts BR
• High Content, Multi-Parameter Analyses in Buccal Cells to Identify Alzheimer's Disease.
  Curr Alzheimer Res Volume: 13 Page(s): 787 - 799
  01/01/2016 Authors: Franois M; Fenech MF; Thomas P; Hor M; Rembach A; Martins RN; Rainey-Smith SR; Masters CL; Ames D; Rowe CC
• Correction: Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging.
  Chem Sci Volume: 6 Page(s): 6677
  11/01/2015 Authors: Paul B; Hare DJ; Bishop DP; Paton C; Nguyen VT; Cole N; Niedzwiecki MM; Andreozzi E; Vais A; Billings JL
• Visualising mouse neuroanatomy and function by metal distribution using laser ablation-inductively coupled plasma-mass spectrometry imaging.
  Chem Sci Volume: 6 Page(s): 5383 - 5393
  10/01/2015 Authors: Paul B; Hare DJ; Bishop DP; Paton C; Nguyen VT; Cole N; Niedwiecki MM; Andreozzi E; Vais A; Billings JL
• Zn II(atsm) is protective in amyotrophic lateral sclerosis model mice via a copper delivery mechanism.
  Neurobiol Dis Volume: 81 Page(s): 20 - 24
  09/01/2015 Authors: McAllum EJ; Roberts BR; Hickey JL; Dang TN; Grubman A; Donnelly PS; Liddell JR; White AR; Crouch PJ
• Cu+ is a cofactor for ubiquitin conjugation and cellular protein degradation
  Volume: 134 Page(s): 343 - 343
  08/01/2015 Authors: Opazo C; Greenough M; Lim C; Lothian A; Roberts B; Luza S; Monahan B; Camakaris J; Bush A
• Amyloid-beta remains a membrane peptide after cleavage. implications for secretion and kinetics of abeta turnover in human brain
  Volume: 134 Page(s): 344 - 344
  08/01/2015 Authors: Roberts B; Lind M; Rembach A; Ryan T; Wagen A; Mclean C; Barnham K; Li Q-X; Villemagne V; Masters C
• Selenium as a potential biomarker for Alzheimer's disease
  Volume: 134 Page(s): 348 - 349
  08/01/2015 Authors: Cardoso B; Roberts B; Bush A; Hare D
• Selenium, selenoproteins and neurodegenerative diseases.
  Metallomics Volume: 7 Page(s): 1213 - 1228
  08/01/2015 Authors: Cardoso BR; Roberts BR; Bush AI; Hare DJ
• Defining how dopamine modulates alpha-synuclein oligomerisation
  Volume: 134 Page(s): 128 - 129
  08/01/2015 Authors: Connor A; Lothian A; Roberts B; Cappai R
• Throwing light on neurodegeneration; small angle X-ray scattering studies on protein misfolding at the australian synchrotron
  Volume: 134 Page(s): 129 - 129
  08/01/2015 Authors: Curtain C; Kirby N; Roberts B; Ryan T
• Identification of proteins interacting with amyloid precursor protein for neurotoxicity and neuroprotection
  Volume: 134 Page(s): 199 - 199
  08/01/2015 Authors: Inampudi C; Jana M; Ciccotosto G; Plummer S; Roberts B; van den Heuvel C; Cappai R
• FluphenazineHCl and Epigallocatechin Gallate Modulate the Rate of Formation and Structural Properties of Apolipoprotein C-II Amyloid Fibrils.
  Biochemistry Volume: 54 Page(s): 3831 - 3838
  06/23/2015 Authors: Zlatic CO; Mao Y; Ryan TM; Mok Y-F; Roberts BR; Howlett GJ; Griffin MDW
• Direct in vivo imaging of ferrous iron dyshomeostasis in ageing Caenorhabditis elegans.
  Chem Sci Volume: 6 Page(s): 2952 - 2962
  05/01/2015 Authors: James SA; Roberts BR; Hare DJ; de Jonge MD; Birchall IE; Jenkins NL; Cherny RA; Bush AI; McColl G
• Elucidating the role of matrix metalloproteases in prion protein proteolysis
  Volume: 9 Page(s): S79 - S79
  04/24/2015 Authors: Lewis V; Johanssen V; Lothian A; Roberts B; Crouch P; Collins S
• The prion protein regulates beta-amyloid-mediated self-renewal of neural stem cells in vitro.
  Stem Cell Res Ther Volume: 6 Page(s): 60
  04/11/2015 Authors: Collins SJ; Tumpach C; Li Q-X; Lewis V; Ryan TM; Roberts B; Drew SC; Lawson VA; Haigh CL
• Decreased plasma iron in Alzheimer's disease is due to transferrin desaturation.
  ACS Chem Neurosci Volume: 6 Page(s): 398 - 402
  03/18/2015 Authors: Hare DJ; Doecke JD; Faux NG; Rembach A; Volitakis I; Fowler CJ; Grimm R; Doble PA; Cherny RA; Masters CL
• Small angle X-ray scattering analysis of Cu(2+)-induced oligomers of the Alzheimer's amyloid peptide.
  Metallomics Volume: 7 Page(s): 536 - 543
  03/01/2015 Authors: Ryan TM; Kirby N; Mertens HDT; Roberts B; Barnham KJ; Cappai R; Pham CLL; Masters CL; Curtain CC
• Stabilization of nontoxic A-oligomers: insights into the mechanism of action of hydroxyquinolines in Alzheimer's disease.
  J Neurosci Volume: 35 Page(s): 2871 - 2884
  02/18/2015 Authors: Ryan TM; Roberts BR; McColl G; Hare DJ; Doble PA; Li Q-X; Lind M; Roberts AM; Mertens HDT; Kirby N
• Neonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease.
  Redox Biol Volume: 4 Page(s): 363 - 374
  01/01/2015 Authors: Berggren KL; Chen J; Fox J; Miller J; Dodds L; Dugas B; Vargas L; Lothian A; McAllum E; Volitakis I
• Traumatic brain injury induces elevation of Co in the human brain.
  Metallomics Volume: 7 Page(s): 66 - 70
  01/01/2015 Authors: Roberts BR; Hare DJ; McLean CA; Conquest A; Lind M; Li Q-X; Bush AI; Masters CL; Morganti-Kossmann M-C; Frugier T
• Improved locomotor function and survival of mice with increased levels of mutant superoxide dismutase 1
  Volume: 130 Page(s): 44 - 44
  08/01/2014 Authors: Roberts BR; Lim NKH; McAllum EJ; Donnelly PS; Hare DJ; Doble PA; Turner BJ; Price KA; Lim SC; Paterson BM
• Traumatic brain injury induces immediate cleavage of amyloid precursor protein in the human brain
  Volume: 130 Page(s): 44 - 45
  08/01/2014 Authors: Frugier T; McLean CA; Crack PJ; Roberts BR
• Decreased serum zinc is an effect of ageing and not Alzheimer's disease.
  Metallomics Volume: 6 Page(s): 1216 - 1219
  07/01/2014 Authors: Rembach A; Hare DJ; Doecke JD; Burnham SC; Volitakis I; Fowler CJ; Cherny RA; McLean C; Grimm R; Martins R
• Oral treatment with Cu(II)(atsm) increases mutant SOD1 in vivo but protects motor neurons and improves the phenotype of a transgenic mouse model of amyotrophic lateral sclerosis.
  J Neurosci Volume: 34 Page(s): 8021 - 8031
  06/04/2014 Authors: Roberts BR; Lim NKH; McAllum EJ; Donnelly PS; Hare DJ; Doble PA; Turner BJ; Price KA; Lim SC; Paterson BM
• Ceruloplasmin and -amyloid precursor protein confer neuroprotection in traumatic brain injury and lower neuronal iron.
  Free Radic Biol Med Volume: 69 Page(s): 331 - 337
  04/01/2014 Authors: Ayton S; Zhang M; Roberts BR; Lam LQ; Lind M; McLean C; Bush AI; Frugier T; Crack PJ; Duce JA
• Improving the metal content of mutant SOD1 as a therapeutic strategy for Amyotrophic Lateral Sclerosis
  Volume: 19 Page(s): S694 - S694
  03/01/2014 Authors: Mcallum E; Lim N; White A; Crouch PJ; Roberts BR; Hickey J; Paterson BM; Donnely P; Barhnam KJ; Williams J
• Guanidine hydrochloride denaturation of dopamine-induced -synuclein oligomers: a small-angle X-ray scattering study.
  Proteins Volume: 82 Page(s): 10 - 21
  01/01/2014 Authors: Pham CLL; Kirby N; Wood K; Ryan T; Roberts B; Sokolova A; Barnham KJ; Masters CL; Knott RB; Cappai R
• Changes in plasma amyloid beta in a longitudinal study of aging and Alzheimer's disease.
  Alzheimers Dement Volume: 10 Page(s): 53 - 61
  01/01/2014 Authors: Rembach A; Faux NG; Watt AD; Pertile KK; Rumble RL; Trounson BO; Fowler CJ; Roberts BR; Perez KA; Li Q-X
• Profiling the iron, copper and zinc content in primary neuron and astrocyte cultures by rapid online quantitative size exclusion chromatography-inductively coupled plasma-mass spectrometry.
  Metallomics Volume: 5 Page(s): 1656 - 1662
  12/01/2013 Authors: Hare DJ; Grubman A; Ryan TM; Lothian A; Liddell JR; Grimm R; Matsuda T; Doble PA; Cherny RA; Bush AI
• Progress towards a consensus on biomarkers for Alzheimer's disease: a review of peripheral analytes.
  Biomark Med Volume: 7 Page(s): 641 - 662
  08/01/2013 Authors: Rembach A; Ryan TM; Roberts BR; Doecke JD; Wilson WJ; Watt AD; Barnham KJ; Masters CL
• Longitudinal analysis of serum copper and ceruloplasmin in Alzheimer's disease.
  J Alzheimers Dis Volume: 34 Page(s): 171 - 182
  01/01/2013 Authors: Rembach A; Doecke JD; Roberts BR; Watt AD; Faux NG; Volitakis I; Pertile KK; Rumble RL; Trounson BO; Fowler CJ
• Metalloproteomics: principles, challenges and applications to neurodegeneration.
  Front Aging Neurosci Volume: 5 Page(s): 35
  01/01/2013 Authors: Lothian A; Hare DJ; Grimm R; Ryan TM; Masters CL; Roberts BR
• Ammonium hydroxide treatment of A produces an aggregate free solution suitable for biophysical and cell culture characterization.
  PeerJ Volume: 1 Page(s): e73
  01/01/2013 Authors: Ryan TM; Caine J; Mertens HDT; Kirby N; Nigro J; Breheney K; Waddington LJ; Streltsov VA; Curtain C; Masters CL
• Decreased copper in Alzheimer's disease brain is predominantly in the soluble extractable fraction.
  Int J Alzheimers Dis Volume: 2013 Page(s): 623241
  01/01/2013 Authors: Rembach A; Hare DJ; Lind M; Fowler CJ; Cherny RA; McLean C; Bush AI; Masters CL; Roberts BR
• Utility of an improved model of amyloid-beta (A) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease.
  Mol Neurodegener Volume: 7 Page(s): 57
  11/21/2012 Authors: McColl G; Roberts BR; Pukala TL; Kenche VB; Roberts CM; Link CD; Ryan TM; Masters CL; Barnham KJ; Bush AI
• Therapeutically increasing mutant SOD1 metallation status attenuates disease symptoms in an ALS mouse model
  Volume: 123 Page(s): 16 - 16
  10/01/2012 Authors: Lim N; Roberts BR; Donnelly PS; Lim S; Beckman JS; Barnham KJ; Li Q; White AR; Crouch PJ
• Small amphipathic molecules modulate secondary structure and amyloid fibril-forming kinetics of Alzheimer disease peptide A(1-42).
  J Biol Chem Volume: 287 Page(s): 16947 - 16954
  05/11/2012 Authors: Ryan TM; Friedhuber A; Lind M; Howlett GJ; Masters C; Roberts BR
• The hypoxia imaging agent CuII(atsm) is neuroprotective and improves motor and cognitive functions in multiple animal models of Parkinson's disease.
  J Exp Med Volume: 209 Page(s): 837 - 854
  04/09/2012 Authors: Hung LW; Villemagne VL; Cheng L; Sherratt NA; Ayton S; White AR; Crouch PJ; Lim S; Leong SL; Wilkins S
• Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export.
  Nat Med Volume: 18 Page(s): 291 - 295
  01/29/2012 Authors: Lei P; Ayton S; Finkelstein DI; Spoerri L; Ciccotosto GD; Wright DK; Wong BXW; Adlard PA; Cherny RA; Lam LQ
• Rapid generation of dityrosine cross-linked A oligomers via Cu-redox cycling.
  Methods Mol Biol Volume: 849 Page(s): 3 - 10
  01/01/2012 Authors: Gunn AP; Roberts BR; Bush AI
• The role of metallobiology and amyloid- peptides in Alzheimer's disease.
  J Neurochem Volume: 120 Suppl 1 Page(s): 149 - 166
  01/01/2012 Authors: Roberts BR; Ryan TM; Bush AI; Masters CL; Duce JA
• Copper promotes the trafficking of the amyloid precursor protein.
  J Biol Chem Volume: 286 Page(s): 8252 - 8262
  03/11/2011 Authors: Acevedo KM; Hung YH; Dalziel AH; Li Q-X; Laughton K; Wikhe K; Rembach A; Roberts B; Masters CL; Bush AI
• Near-infrared fluorescence imaging of apoptotic neuronal cell death in a live animal model of prion disease.
  ACS Chem Neurosci Volume: 1 Page(s): 720 - 727
  11/17/2010 Authors: Lawson VA; Haigh CL; Roberts B; Kenche VB; Klemm HMJ; Masters CL; Collins SJ; Barnham KJ; Drew SC
• Cu,Zn-superoxide dismutase increases toxicity of mutant and zinc-deficient superoxide dismutase by enhancing protein stability.
  J Biol Chem Volume: 285 Page(s): 33885 - 33897
  10/29/2010 Authors: Garner MA; Ricart KC; Roberts BR; Bomben VC; Basso M; Ye Y; Sahawneh J; Franco MC; Beckman JS; Estvez AG
• The Caenorhabditis elegans A beta 1-42 model of Alzheimer disease predominantly expresses A beta 3-42.
  J Biol Chem Volume: 284 Page(s): 22697 - 22702
  08/21/2009 Authors: McColl G; Roberts BR; Gunn AP; Perez KA; Tew DJ; Masters CL; Barnham KJ; Cherny RA; Bush AI
• Structural characterization of zinc-deficient human superoxide dismutase and implications for ALS.
  J Mol Biol Volume: 373 Page(s): 877 - 890
  11/02/2007 Authors: Roberts BR; Tainer JA; Getzoff ED; Malencik DA; Anderson SR; Bomben VC; Meyers KR; Karplus PA; Beckman JS
• Why are ALS mutations to SOD dominate? Cu, ZnSOD stabilization of zinc-deficient SOD as a heterodimer
  Volume: 41 Page(s): S167 - S168
  01/01/2006 Authors: Roberts BR; Malencik D; Beckman JS
• Oxidized and synchrotron cleaved structures of the disulfide redox center in the N-terminal domain of Salmonella typhimurium AhpF.
  Protein Sci Volume: 14 Page(s): 2414 - 2420
  09/01/2005 Authors: Roberts BR; Wood ZA; Jnsson TJ; Poole LB; Karplus PA
• It takes two to tango - Structural insight into the motor neuron toxicity of zinc deficient superoxide dismutase
  Volume: 39 Page(s): S63 - S64
  01/01/2005 Authors: Roberts B; Tainer J; Estevez A; Karplus A; Beckman J
• Peroxynitrite and nitration of green fluorescent protein
  Volume: 35 Page(s): S109 - S110
  01/01/2003 Authors: Roberts BR; Beckman JS