Congratulations to Will Hudson and Emily Rye for their paper, "Distal Substitutions Drive Divergent DNA Specificity Among Paralogous Transcription Factors Through Subdivision of Conformational Space," that was recently published in PNAS. Will is a former member of the Ortlund Lab and currently a Postdoc in Rafi Ahmed's lab. Emily is a BCDB graduate student in the Ortlund Lab. The work reveals that a mechanism by which stress hormones inhibit the immune system, which appeared to be relatively new in evolution, may actually be hundreds of millions of years old.
