Spangle Laboratory

Led by principal investigator Jennifer Spangle PhD, the Spangle Laboratory is located at Winship Cancer Institute of Emory University in Atlanta, Georgia.

Principal Investigator

Jennifer M. Spangle, PhD is an Assistant Professor of Radiation Oncology at the Winship Cancer Institute of Emory University.

Email | Phone: (404)-778-6173

Meet Dr. Spangle and her lab team

Research

Our laboratory is focused on understanding how signaling pathways such as PI3K rewire the epigenome and exploiting this information to develop durable combination therapies for the treatment of cancers characterized by aberrant PI3K activation.

Publications

Dr. Spangle has been published in numerous peer-reviewed scientific journals including Journal of Molecular Medicine, PNAS, and Cell Reports.

Lab Team

Our lab team consists of talented scientists with expertise in cancer biology, signal transduction and epigenetics.

Lab Team Announcements

More Announcements

March 2023

Sandhya Lohano joins the Spangle lab for undergraduate research as part of Team Oncohistone. Welcome Sandhya!

March 2023

BCDB student Dory Fawwal joins the Spangle and Corbett labs to start a new joint project defining and characterizing novel histone mutations in cancer. Welcome Dory!

March 2023

Richard Lee successfully defends his undergraduate honors thesis. Cheers!

February 2023

Jenn receives the NSF CAREER award for research focused on understanding how histone mutations perturb gene expression. This will lead to further development of Team Histone together with Dr. Anita Corbett and the Corbett lab. Congratulations!