Currently, the set of available reference data and downloadable image sets consists of thoracic 4DCT images and CT image pairs from COPDgene study archive. We will update the library as more cases are added, and will inform all of our registered users as they become available.
Download information
Included with each case are 2 text files containing coordinate information for the reference landmarks on the inhalation (iBH-CT) and exhalation (eBH-CT) breath-hold CT images:
- "caseID_300_iBH_xyz_r1.txt", and
- "caseID_300_eBH_xyz_r1.txt"
To access the download of image sets below from the reference data provided, investigators are encouraged to complete our request form. Once completed, a password to access the available file(s) in Dropbox will be provided.
Reference Publications
All of the datasets for case numbers COPD1-COPD10 have previously been reported as part of original peer-reviewed publications describing the data acquisition and analysis process.
Castillo R, Castillo E, Fuentes D, Ahmad M, Wood AM, Ludwig MS, Guerrero T. 2013. A reference dataset for deformable image registration spatial accuracy evaluation using the COPDgene study archive. Phys Med Biol 58 2861-2877.
Visit Publications for comprehensive list.
Image Sets and Reference Data
For the COPD images, the full point set is identified between the maximum inhalation and exhalation component phase images. Additionally, a subset of 75 features has been propagated onto each of the expiratory phase images (i.e., T00, T10, T20, T30, T40, and T50).
Each case is identified according to the given label.
- The image dimensions are given in voxel units, and the voxel dimensions are given in millimeters.
- The "# Features" designates the total quantity of unique landmark features identified for each case.
- The "Displacement" shows the mean (and standard deviation) displacement of the complete primary feature set.
- The entries under "# Repeats" are formatted as (Nm< / Nobs), where Nm is the number of repeat registration measurements performed by each of Nobs independent observers.
- The "Observers" column shows the combined mean (and standard deviation) repeat registration error for the set of Nobs data sets.
Surface renderings of the inhale lung volume are shown, overlain with displacement vectors (iBH-CT --> eBH-CT) for each of the validation landmarks. All surface renderings were generated in the MATLAB (Mathworks, Sunnyvale, CA) environment.