Jocelyn Grunwell
Overview
Dr. Jocelyn R. Grunwell, MD, PhD is an Assistant Professor of Pediatrics in the Division of Critical Care Medicine at Emory University and Childrens Healthcare of Atlanta. Dr. Grunwell completed her undergraduate studies in chemistry at Harvard University. She then attended graduate school at the University of California, Berkeley where she received a PhD in Bio-organic Chemistry. After completing a post-doctoral fellowship in biochemistry at the University of California San Francisco, where she was a Damon Runyon post-doctoral fellow, she attended the Stanford University School of Medicine. She completed her Pediatrics Residency at Emory University in 2012. She was the Assistant Program Director (Chief Resident) for the Emory Pediatrics Residency program from 2012 - 2013. She completed her subspecialty fellowship training in pediatric critical care medicine at Emory in 2017 where she was a T32 post-doctoral fellow. From 2018 - 2020, Dr. Grunwell was an Atlanta Pediatric K12 Scholar. In 2020, Dr. Grunwell was awarded Junior Faculty Researcher of the Year. She is currently a NHLBI K23 awardee. Dr. Grunwell completed the postgraduate coursework for the Master of Science in Clinical and Translational Research (MSCR) degree at Emory in 2022.
Dr. Grunwells research focuses on the airway immune response in children who are at risk for developing and who are diagnosed with acute respiratory distress syndrome. She has a research program in immunophenotyping and determining patient-reported outcomes following life-threatening asthma exacerbations. She collaborates with engineers at the Georgia Institute of Technology to develop a lung-on-a-chip model and data scientists and machine learning experts at Emory/Georgia Tech to discover transcriptomic and metabolomic signatures of pediatric ARDS. In addition to her translational research, she participates in the Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) network and collaborates on multi-center observational and clinical trials to improve the care of critically ill children with ARDS (LEOPARDS), influenza (PICFLU2), sepsis (PROMPT-BOLUS), and multiple organ dysfunction (PARADIGM, TROPICS). She is a member of the SCCM Discover Research Network and the Pediatric Acute Lung Injury Consensus Conference (PALICC-2) guideline committee.
In 2022, Dr. Grunwell became the Research Director for the Division of Pediatric Critical Care Medicine.
Focus of practice
Critical care medicine
Areas of interest
Pediatric acute respiratory distress syndrome
Critical and near-fatal asthma
Sepsis
Multiple Organ Dysfunction Syndrome
Social Determinants of Health
Professional affiliations
Society of Critical Care Medicine
American Association of Immunologists
American Thoracic Society
Pediatric Acute Lung Injury and Sepsis Investigators
Shock Society
Research interests
Understanding heterogeneity of complex critical illness syndromes with subphenotyping and endotyping strategies
Using machine learning to develop clinical prediction models and clinical decision support
Developing preclinical models that represent pediatric acute respiratory distress syndrome to identify underlying mechanisms, heterogeneity, and test interventions targeted at causal biological pathways
Research
Publications
-
High-throughput quantitation of human neutrophil recruitment and functional responses in an air-blood barrier array.
APL Bioeng Volume: 9 Page(s): 026110
06/01/2025 Authors: Viola H; Chen L-H; Jo S; Washington K; Selva C; Li A; Feng D; Giacalone V; Stephenson ST; Cottrill K -
Association of the child opportunity index with in-hospital mortality and persistence of organ dysfunction at one week after onset of Phoenix Sepsis among children admitted to the pediatric intensive care unit with suspected infection.
PLOS Digit Health Volume: 4 Page(s): e0000763
04/01/2025 Authors: Moore R; Chanci D; Brown SR; Ripple MJ; Bishop NR; Grunwell J; Kamaleswaran R -
Tackling the small imbalanced horizontal dataset regressions by Stability Selection and SMOGN: a case study of ventilation-free days prediction in the pediatric intensive care unit and the importance of PRISM.
Int J Med Inform Volume: 196 Page(s): 105809
04/01/2025 Authors: Rad M; Rafiei A; Grunwell J; Kamaleswaran R -
Development of a Core Critical Care Data Dictionary With Common Data Elements to Characterize Critical Illness and Injuries Using a Modified Delphi Method.
Crit Care Med
02/21/2025 Authors: Murphy DJ; Anderson W; Heavner SH; Al-Hakim T; Cruz-Cano R; Laudanski K; Kamaleswaran R; Badawi O; Engel H; Grunwell J -
Asthma Phenotypes and Biomarkers.
Respir Care
02/10/2025 Authors: Grunwell JR; Fitzpatrick AM -
PROGNOSTIC ACCURACY OF MACHINE LEARNING MODELS FOR IN-HOSPITAL MORTALITY AMONG CHILDREN WITH PHOENIX SEPSIS ADMITTED TO THE PEDIATRIC INTENSIVE CARE UNIT.
Shock Volume: 63 Page(s): 80 - 87
01/01/2025 Authors: Moore R; Chanci D; Brown S; Ripple MJ; Bishop NR; Grunwell J; Kamaleswaran R -
RNA Sequencing Analysis of Monocytes Exposed to Airway Fluid From Children With Pediatric Acute Respiratory Distress Syndrome.
Crit Care Explor Volume: 6 Page(s): e1125
10/01/2024 Authors: Grunwell JR; Huang M; Stephenson ST; Tidwell M; Ripple MJ; Fitzpatrick AM; Kamaleswaran R -
Clinical and inflammatory features of traffic-related diesel exposure in children with asthma.
Ann Allergy Asthma Immunol Volume: 133 Page(s): 393 - 402.e4
10/01/2024 Authors: Fitzpatrick AM; Mohammad AF; Desher K; Mutic AD; Stephenson ST; Dallalio GA; Grunwell JR -
Assessing Social Determinants of Health During Critical Illness: Implications and Methodologies.
Crit Care Clin Volume: 40 Page(s): 623 - 640
10/01/2024 Authors: Magee PM; Asp RA; Myers CN; Grunwell JR; Paquette E; Akande MY -
Association between comorbidities at ICU admission and post-Sepsis physical impairment: A retrospective cohort study.
J Crit Care Volume: 83 Page(s): 154833
10/01/2024 Authors: Kobara S; Yamamoto R; Rad MG; Grunwell JR; Hikota N; Uzawa Y; Hayashi Y; Coopersmith CM; Kamaleswaran R