Publications

Display 15 publications in PubMed

1. SARS-CoV-2 infection induces a pro-inflammatory cytokine response through cGAS-STING and NF-κB.
Neufeldt CJ, Cerikan B, Cortese M, Frankish J, Lee JY, Plociennikowska A, Heigwer F, Prasad V, Joecks S, Burkart SS, Zander DY, Subramanian B, Gimi R, Padmanabhan S, Iyer R, Gendarme M, El Debs B, Halama N, Merle U, Boutros M, Binder M, Bartenschlager R.
Commun Biol. 2022 Jan 12;5(1):45. doi: 10.1038/s42003-021-02983-5.
PMID: 35022513

2. Convergent use of phosphatidic acid for hepatitis C virus and SARS-CoV-2 replication organelle formation.
Tabata K, Prasad V, Paul D, Lee JY, Pham MT, Twu WI, Neufeldt CJ, Cortese M, Cerikan B, Stahl Y, Joecks S, Tran CS, Lüchtenborg C, V'kovski P, Hörmann K, Müller AC, Zitzmann C, Haselmann U, Beneke J, Kaderali L, Erfle H, Thiel V, Lohmann V, Superti-Furga G, Brügger B, Bartenschlager R.
Nat Commun. 2021 Dec 14;12(1):7276. doi: 10.1038/s41467-021-27511-1.
PMID: 34907161 Free PMC article.

3. Determinants in Nonstructural Protein 4A of Dengue Virus Required for RNA Replication and Replication Organelle Biogenesis.
Cortese M, Mulder K, Chatel-Chaix L, Scaturro P, Cerikan B, Plaszczyca A, Haselmann U, Bartenschlager M, Neufeldt CJ, Bartenschlager R.
J Virol. 2021 Oct 13;95(21):e0131021. doi: 10.1128/JVI.01310-21. Epub 2021 Aug 11.
PMID: 34379504

4. Global analysis of protein-RNA interactions in SARS-CoV-2-infected cells reveals key regulators of infection.
Kamel W, Noerenberg M, Cerikan B, Chen H, Järvelin AI, Kammoun M, Lee JY, Shuai N, Garcia-Moreno M, Andrejeva A, Deery MJ, Johnson N, Neufeldt CJ, Cortese M, Knight ML, Lilley KS, Martinez J, Davis I, Bartenschlager R, Mohammed S, Castello A.
Mol Cell. 2021 Jul 1;81(13):2851-2867.e7. doi: 10.1016/j.molcel.2021.05.023. Epub 2021 May 24.
PMID: 34118193 Free PMC article.

5. A Versatile Reporter System To Monitor Virus-Infected Cells and Its Application to Dengue Virus and SARS-CoV-2.
Pahmeier F, Neufeldt CJ, Cerikan B, Prasad V, Pape C, Laketa V, Ruggieri A, Bartenschlager R, Cortese M.
J Virol. 2021 Jan 28;95(4):e01715-20. doi: 10.1128/JVI.01715-20. Print 2021 Jan 28.
PMID: 33257477 Free PMC article.

6. Integrative Imaging Reveals SARS-CoV-2-Induced Reshaping of Subcellular Morphologies.
Cortese M, Lee JY, Cerikan B, Neufeldt CJ, Oorschot VMJ, Köhrer S, Hennies J, Schieber NL, Ronchi P, Mizzon G, Romero-Brey I, Santarella-Mellwig R, Schorb M, Boermel M, Mocaer K, Beckwith MS, Templin RM, Gross V, Pape C, Tischer C, Frankish J, Horvat NK, Laketa V, Stanifer M, Boulant S, Ruggieri A, Chatel-Chaix L, Schwab Y, Bartenschlager R.
Cell Host Microbe. 2020 Dec 9;28(6):853-866.e5. doi: 10.1016/j.chom.2020.11.003. Epub 2020 Nov 17.
PMID: 33245857 Free PMC article.

7. SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography.
Klein S, Cortese M, Winter SL, Wachsmuth-Melm M, Neufeldt CJ, Cerikan B, Stanifer ML, Boulant S, Bartenschlager R, Chlanda P.
Nat Commun. 2020 Nov 18;11(1):5885. doi: 10.1038/s41467-020-19619-7.
PMID: 33208793 Free PMC article.

8. Structures and distributions of SARS-CoV-2 spike proteins on intact virions.
Ke Z, Oton J, Qu K, Cortese M, Zila V, McKeane L, Nakane T, Zivanov J, Neufeldt CJ, Cerikan B, Lu JM, Peukes J, Xiong X, Kräusslich HG, Scheres SHW, Bartenschlager R, Briggs JAG.
Nature. 2020 Dec;588(7838):498-502. doi: 10.1038/s41586-020-2665-2. Epub 2020 Aug 17.
PMID: 32805734 Free PMC article.

9. A Non-Replicative Role of the 3' Terminal Sequence of the Dengue Virus Genome in Membranous Replication Organelle Formation.
Cerikan B, Goellner S, Neufeldt CJ, Haselmann U, Mulder K, Chatel-Chaix L, Cortese M, Bartenschlager R.
Cell Rep. 2020 Jul 7;32(1):107859. doi: 10.1016/j.celrep.2020.107859.
PMID: 32640225 Free PMC article.

10. ER-shaping atlastin proteins act as central hubs to promote flavivirus replication and virion assembly.
Neufeldt CJ, Cortese M, Scaturro P, Cerikan B, Wideman JG, Tabata K, Moraes T, Oleksiuk O, Pichlmair A, Bartenschlager R.
Nat Microbiol. 2019 Dec;4(12):2416-2429. doi: 10.1038/s41564-019-0586-3. Epub 2019 Oct 21.
PMID: 31636417 Free PMC article.

11. Rewiring cellular networks by members of the Flaviviridae family.
Neufeldt CJ, Cortese M, Acosta EG, Bartenschlager R.
Nat Rev Microbiol. 2018 Feb 12;16(3):125-142. doi: 10.1038/nrmicro.2017.170.
PMID: 29430005 Free PMC article. Review.

12. Ultrastructural Characterization of Zika Virus Replication Factories.
Cortese M, Goellner S, Acosta EG, Neufeldt CJ, Oleksiuk O, Lampe M, Haselmann U, Funaya C, Schieber N, Ronchi P, Schorb M, Pruunsild P, Schwab Y, Chatel-Chaix L, Ruggieri A, Bartenschlager R.
Cell Rep. 2017 Feb 28;18(9):2113-2123. doi: 10.1016/j.celrep.2017.02.014.
PMID: 28249158 Free PMC article.

13. Dengue Virus Perturbs Mitochondrial Morphodynamics to Dampen Innate Immune Responses.
Chatel-Chaix L, Cortese M, Romero-Brey I, Bender S, Neufeldt CJ, Fischl W, Scaturro P, Schieber N, Schwab Y, Fischer B, Ruggieri A, Bartenschlager R.
Cell Host Microbe. 2016 Sep 14;20(3):342-356. doi: 10.1016/j.chom.2016.07.008. Epub 2016 Aug 18.
PMID: 27545046 Free PMC article.

14. The Hepatitis C Virus-Induced Membranous Web and Associated Nuclear Transport Machinery Limit Access of Pattern Recognition Receptors to Viral Replication Sites.
Neufeldt CJ, Joyce MA, Van Buuren N, Levin A, Kirkegaard K, Gale M Jr, Tyrrell DL, Wozniak RW.
PLoS Pathog. 2016 Feb 10;12(2):e1005428. doi: 10.1371/journal.ppat.1005428. eCollection 2016 Feb.
PMID: 26863439 Free PMC article.

15. Hepatitis C virus-induced cytoplasmic organelles use the nuclear transport machinery to establish an environment conducive to virus replication.
Neufeldt CJ, Joyce MA, Levin A, Steenbergen RH, Pang D, Shields J, Tyrrell DL, Wozniak RW.
PLoS Pathog. 2013 Oct;9(10):e1003744. doi: 10.1371/journal.ppat.1003744. Epub 2013 Oct 31.
PMID: 24204278 Free PMC article.