Research

Faculty and fellows in the Medical Toxicology section have multiple active research projects, with a particular focus on Addiction Medicine, Global Health, and the human health effects of radiation. Faculty have received external research funding from multiple NIH institutes, as well as internal grant funding from the Emory Medical Care Foundation. In addition to fellows, trainees of all levels, including medical students, residents, and pharmacists also commonly participate in our research projects.

Recently, we were selected as a site for the ED-INNOVATION study, a multisite NIH-funded randomized clinical trial assessing the efficacy of extended-release buprenorphine in emergency department patients.

Current and former fellows have presented their work at national conferences including:

• North American Congress of Clinical Toxicology
• American College of Medical Toxicology Annual Scientific Meeting
• American Society of Addiction Medicine
• American College of Emergency Physicians

Our work has been published in Medical Toxicology journals including Clinical Toxicology and Journal of Medical Toxicology, as well as more widely circulated journals such as American Journal of Public Health, Chest, and Morbidity and Mortality Weekly Report (MMWR).   

Selected recent publications: 

Addiction Medicine

Global Health

EVALI Outbreak

Epidemiology and Public Health

NACCT 2020 – Poster (research)

1. Calls to Toxicology Back-up at a Regional Poison Center, 2012-2019. Therriault C, Hon S, Moran TP, Carpenter J.
2. Characteristics and Trends in Lacrimator Exposures Reported to the National Poison Data System, United States, January 1,2000-December 31, 2019. Therriault C, Law R, Svendsen E, Chang A.

ACMT ASM 2021 – Poster (case report)

1. Cocaine Cardiac Arrest – Hassan, Andres, Kazzi
2. Resolution of Severe Sodium Nitrite-Induced Methemoglobinemia with Single Dose Methylene Blue. Filkins B, Debruyn B, Gittinger M.

ACMT ASM 2021 – Poster (research)

1. Circumferential Measurements: Hisssss-torically Discussed, Painfully Underreported. Eisenstat M, Carpenter J, Guzman-Soto A, Kiernan E.
2. Logistical Holes In Whole Bowel Irrigation. Suen K, Guzman-Soto A, Nogee D, Filkins P, Walsh C, Moran TP, Carpenter J.
3. Clinical Characteristics of Kratom Exposures Reported to Georgia Poison Center: A Retrospective Review. Palungwachira P,…Kazzi Z. (MODERATED POSTER)

3. Suen K, Guzman Soto A, Nogee D, Filkins P, Walsh C, Carpenter J. Compliance to whole bowel irrigation recommendations: a single poison center study Toxicology Communications 7(1):1-7 31 Dec 2023
4. Nwanaji-Enwerem JC, Rivera Blanco LE, Kiernan EA, Morgan BW, Gittinger MH, Steck AR. Revisiting emergency department use of buprenorphine as a primary analgesic in nonopioid use disorder patients post-X-waiver. Acad Emerg Med 30(12):1272-1274 Dec 2023 
5. Razavi SA, Stewart CM, Nogee DP, Geller RJ, Seiler JG. Upper Extremity Crotalid Envenomation: A Review of Incidence and Recent Trends in Management of Snakebites. J Hand Surg Am 48(12):1277.e1-1277.e6 Dec 2023
6. Illg Z, Carpenter J, Moran TP, Kiernan E, Murray BP. Hydrofluoric acid ingestions: Retrospective evaluations from cases reported to the National Poison Data System 2007-2017. J Am Coll Emerg Physicians Open 4(5):e13059 Oct 2023
7. Carpenter JE, Catalanotti J, Notis M, Brokus C, Moran TP, Akselrod H, Burkholder G, Eaton EF, Kuo I, Mai W, et al. Use of nonstigmatizing language is associated with improved outcomes in hospitalized people who inject drugs. J Hosp Med 18(8):670-676 Aug 2023
8. Heiman E, Lanh S, Moran TP, Steck A, Carpenter J. Electronic Advisories Increase Naloxone Prescribing Across Health Care Settings Journal of General Internal Medicine 38(6):1402-1409 May 2023
9. Ruff JC, Zhang Y, Bui DP, Therriault C, Nogee D, Guthery SL, Daniel J. Notes from the Field: Acute Nonviral Hepatitis Linked to a Brand of Alkaline Bottled Water - Clark County, Nevada and California, 2020. Morb Mortal Wkly Rep. 2021 Nov 19;70(46):1617-1619.

1. ALfaifi MS, Barada KA, Kazzi ZN, Mneimneh ZS, Hitti EA, Malaeb MA, Mustapha SA, Gittinger MH. N-Acetyl Cysteine to Treat Polygonum multiflorum Hepatotoxicity: A Case Report. Case Reports in Clinical Medicine. 2021 Jan 18;10(1):1-7
2. Kiernan E, Carpenter JE, Dunkley CA, Koch D, Morgan BW, Steck AR, Murray BP. Elevated Methemoglobin Levels in a Patient Treated with Hydroxocobalamin After Suspected Cyanide Exposure. The Journal of Emergency Medicine. 2020 Nov 1;59(5):e157-62
3. El Zahran T, Mostafa H, Hamade H, Mneimneh Z, Kazzi Z, El Sayed MJ. Riot-related injuries managed at a hospital in Beirut, Lebanon. The American Journal of Emergency Medicine. 2021 Apr 1;42:55-9
4. Murray BP, Carpenter JE, Sayers J, Yeh M, Beau J, Kiernan EA, Wolf MJ, Bolton TA, Kazzi Z. Two Cases of Serotonin Syndrome After Bupropion Overdose Treated With Cyproheptadine. The Journal of Emergency Medicine. 2020 Dec 8
5. Hamade H, Sahin A, Sukhn C, El Tawil C, Rizk J, Kazzi Z, El Zahran T. Human Zinc Phosphide Exposure in Lebanon: A Case Report and Review of the Literature. Clinical Practice and Cases in Emergency Medicine. 2021 Feb;5(1):50
6. Sahin A, Layer M, Kleiman R, Punja M, Lopez G, Alotiabi S, Kazzi Z. Loperamide-induced Torsade de Pointes: a case report. Journal of Emergency Medicine. 2020 May 1;58(5):845.
7. Sahin A, Atti SK, Kiernan EA, Alotiabi S, Kazzi Z. The possibility of acute betel nut toxicity: a case report. Journal of Emergency Medicine. 2020 May 1;58(5):845

1. Kiernan E, Therriault C, Eisenstat M, Nogee D, de Olano J. Articles You Might Have Missed. Journal of Medical Toxicology. 2021 Feb 23:1-5

Active

Retained lead (Smith, Kazzi)

ED-INNOVATION (Carpenter, De Olano, Morgan, Steck)

SCOUT-ED (Carpenter, Steck, Sarker, Rupp)

CHOICE (Del Rio, Carpenter, Steck)

Applied for

Toxicosurveillance (Sarker, Carpenter)