RZHRG Publications | Emory School of Medicine

2020

Motivational interviewing to promote long-acting reversible contraception among Rwandan couples wishing to prevent or delay pregnancy. Mukamuyango J, Ingabire R, Parker R, Nyombayire J, Easter SR, Wall KM, et al.Am J Obstet Gynecol. 2020;222(4S):S919 e1-S e12. http://dx.doi.org/10.1016/j.ajog.2019.11.1280

A couple-focused, integrated unplanned pregnancy and HIV prevention program in urban and rural Zambia.Malama K, Kilembe W, Inambao M, Hoagland A, Sharkey T, Parker R, et al. Am J Obstet Gynecol. 2020;222(4S):S915 e1-S e10. http://dx.doi.org/10.1016/j.ajog.2020.01.007

Fertility intentions and long-acting reversible contraceptive use among HIV-negative single mothers in Zambia. Li JL, Kilembe W, Inambao M, Vwalika B, Parker R, Sharkey T, et al. Am J Obstet Gynecol. 2020;222(4S):S917 e1-S e15. http://dx.doi.org/10.1016/j.ajog.2019.12.269

Sociodemographic factors and STIs associated with Chlamydia trachomatis and Neisseria gonorrhoeae infections in Zambian female sex workers and single mothers. Connolly S, Wall KM, Parker R, Kilembe W, Inambao M, Visoiu AM, et al. Int J STD AIDS. 2020;31(4):364-74. http://dx.doi.org/10.1177/0956462419894453

Factors associated with alcohol use before sex among HIV-negative female sex workers in Zambia. Malama K, Sagaon-Teyssier L, Parker R, Tichacek A, Sharkey T, Kilembe W, et al. Int J STD AIDS. 2020;31(2):119-26. http://dx.doi.org/10.1177/0956462419886159

Differential Vpu-Mediated CD4 and Tetherin Downregulation Functions among Major HIV-1 Group M Subtypes.Umviligihozo G, Cobarrubias KD, Chandrarathna S, Jin SW, Reddy N, Byakwaga H, et al. J Virol. 2020;94(14). http://dx.doi.org/10.1128/JVI.00293-20

Identifying the immune interactions underlying HLA class I disease associations. Debebe BJ, Boelen L, Lee JC, Investigators IPC, Thio CL, Astemborski J, et al. Elife. 2020;9. http://dx.doi.org/10.7554/eLife.54558

Better Viral Control despite Higher CD4(+) T Cell Activation during Acute HIV-1 Infection in Zambian Women Is Linked to the Sex Hormone Estradiol. El-Badry E, Macharia G, Claiborne D, Brooks K, Dilernia DA, Goepfert P, et al. J Virol. 2020;94(16). http://dx.doi.org/10.1128/JVI.00758-20

A Population-Specific Optimized GeneXpert Pooling Algorithm for Chlamydia trachomatis and Neisseria gonorrhoeae To Reduce Cost of Molecular Sexually Transmitted Infection Screening in Resource-Limited Settings. Connolly S, Kilembe W, Inambao M, Visoiu AM, Sharkey T, Parker R, et al. J Clin Microbiol. 2020;58(9):39. http://dx.doi.org/10.1128/JCM.00176-20

HIV-1 variants are archived throughout infection and persist in the reservoir. Brooks K, Jones BR, Dilernia DA, Wilkins DJ, Claiborne DT, McInally S, et al. PLoS Pathog. 2020;16(6):e1008378. http://dx.doi.org/10.1371/journal.ppat.1008378

Cost-effectiveness of couples' voluntary HIV counselling and testing in six African countries: a modelling study guided by an HIV prevention cascade framework. Wall KM, Inambao M, Kilembe W, Karita E, Chomba E, Vwalika B, et al. J Int AIDS Soc. 2020;23 Suppl 3:e25522. http://dx.doi.org/10.1002/jia2.25522

Uptake of long acting reversible contraception following integrated couples HIV and fertility goal-based family planning counselling in Catholic and non-Catholic, urban and rural government health centers in Kigali, Rwanda. Mukamuyango J, Ingabire R, Parker R, Nyombayire J, Abaasa A, Asiki G, et al. Reprod Health. 2020;17(1):126. http://dx.doi.org/10.1186/s12978-020-00981-0

Cost-effectiveness of integrated HIV prevention and family planning services for Zambian couples. Wall KM, Kilembe W, Inambao M, Hoagland A, Sharkey T, Malama K, et al. AIDS. 2020;34(11):1633-42. http://dx.doi.org/10.1097/QAD.0000000000002584

Cohort profile: IAVI's HIV epidemiology and early infection cohort studies in Africa to support vaccine discovery. Price MA, Kilembe W, Ruzagira E, Karita E, Inambao M, Sanders EJ, et al. Int J Epidemiol. 2020;2:39. http://dx.doi.org/10.1093/ije/dyaa100

Postpartum long-acting contraception uptake and service delivery outcomes after a multilevel intervention in Kigali, Rwanda. Espey J, Ingabire R, Nyombayire J, Hoagland A, Da Costa V, Mazzei A, et al. BMJ Sex Reprod Health. 2020. http://dx.doi.org/10.1136/bmjsrh-2020-200741

HIV infection and engagement in HIV care cascade among men who have sex with men and transgender women in Kigali, Rwanda: a cross-sectional study. Twahirwa Rwema JO, Lyons CE, Herbst S, Liestman B, Nyombayire J, Ketende S, et al. J Int AIDS Soc. 2020;23 Suppl 6(Suppl 6):e25604. http://dx.doi.org/10.1002/jia2.25604

Loss to follow-up among female sex workers in Zambia: findings from a five-year HIV-incidence cohort. Malama K, Sagaon-Teyssier L, Gosset A, Parker R, Wall KM, Tichacek A, et al. Afr J AIDS Res. 2020;19(4):296-303. http://dx.doi.org/10.2989/16085906.2020.1836005

2019

Reduced frequency of HIV superinfection in a high-risk cohort in Zambia. Woodson E, Basu D, Olszewski H, Gilmour J, Brill I, Kilembe W, et al. Virology. 2019;535:11-9. DOI

HIV testing and counselling couples together for affordable HIV prevention in Africa. Wall KM, Inambao M, Kilembe W, Karita E, Vwalika B, Mulenga J, et al. Int J Epidemiol. 2019;48(1):217-27. DOI

Control of the HIV-1 Load Varies by Viral Subtype in a Large Cohort of African Adults With Incident HIV-1 Infection. Price MA, Rida W, Kilembe W, Karita E, Inambao M, Ruzagira E, et al. J Infect Dis. 2019;220(3):432-41. DOI

Community health worker promotions increase uptake of long-acting reversible contraception in Rwanda. Mazzei A, Ingabire R, Mukamuyango J, Nyombayire J, Sinabamenye R, Bayingana R, et al. Reprod Health. 2019;16(1):75. DOI

Client-Initiated Violence Against Zambian Female Sex Workers: Prevalence and Associations With Behavior, Environment, and Sexual History. Malama K, Sagaon-Teyssier L, Parker R, Tichacek A, Sharkey T, Kilembe W, et al. J Interpers Violence. 2019:886260519860083. DOI

Single Mothers and Female Sex Workers in Zambia Have Similar Risk Profiles. Kilembe W, Inambao M, Sharkey T, Wall KM, Parker R, Himukumbwa C, et al. AIDS Res Hum Retroviruses. 2019;35(9):814-25. DOI

Female sex workers in Kigali, Rwanda: a key population at risk of HIV, sexually transmitted infections, and unplanned pregnancy. Ingabire R, Parker R, Nyombayire J, Ko JE, Mukamuyango J, Bizimana J, et al. International journal of STD & AIDS. 2019;30(6):557-68. DOI

Development and Uptake of Long-Acting Reversible Contraception Services in Rwanda, 2009-2016. Ingabire R, Mukamuyango J, Nyombayire J, Easter SR, Parker R, Mazzei A, et al. Journal of women's health (2002). 2019;28(12):1640-9. DOI

Hormonal Contraception and Vaginal Infections Among Couples Who Are Human Immunodeficiency Virus Serodiscordant in Lusaka, Zambia. Haddad LB, Wall KM, Tote K, Kilembe W, Vwailika B, Sharkey T, et al. Obstet Gynecol. 2019;134(3):573-80. DOI

An Exploratory Analysis of Factors Associated With Interest in Postpartum Intrauterine Device Uptake Among Pregnant Women and Couples in Kigali, Rwanda. Da Costa V, Ingabire R, Sinabamenye R, Karita E, Umutoni V, Hoagland A, et al. Clin Med Insights Reprod Health. 2019;13:1179558119886843. DOI

Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis. Claiborne DT, Scully EP, Palmer CD, Prince JL, Macharia GN, Kopycinski J, et al. PLoS pathogens. 2019;15(8):e1007981. DOI

Predominance of the heterozygous CCR5 delta-24 deletion in African individuals resistant to HIV infection might be related to a defect in CCR5 addressing at the cell surface. Arendt V, Amand M, Iserentant G, Lemaire M, Masquelier C, Ndayisaba GF, et al. J Int AIDS Soc. 2019;22(9):e25384. DOI

2018

Couples' voluntary HIV counseling and testing provider training evaluation, Zambia. Wu KY, Oppert M, Wall KM, Inambao M, Simpungwe MK, Ahmed N, et al. Health Promot Int. 2018;33(4):580-8. DOI

HIV transmission in discordant couples in Africa in the context of antiretroviral therapy availability. Woodson E, Goldberg A, Michelo C, Basu D, Tao S, Schinazi R, et al. AIDS. 2018;32(12):1613-23. DOI

Immunogenetic factors in early immune control of human immunodeficiency virus type 1 (HIV-1) infection: Evaluation of HLA class I amino acid variants in two African populations. Wiener HW, Shrestha S, Lu H, Karita E, Kilembe W, Allen S, et al. Human immunology. 2018;79(3):166-71. DOI

Schistosomiasis is associated with incident HIV transmission and death in Zambia. Wall KM, Kilembe W, Vwalika B, Dinh C, Livingston P, Lee YM, et al. PLoS Negl Trop Dis. 2018;12(12):e0006902. DOI

Cost per insertion and couple year of protection for post-partum intrauterine devices and implants provided during service scale-up in Kigali, Rwanda. Wall KM, Ingabire R, Allen S, Karita E. Gates Open Research. 2018;2(39). DOI

Rwandan stakeholder perspectives of integrated family planning and HIV services. Wall KM, Bayingana R, Ingabire R, Ahlschlager L, Tichacek A, Allen S, et al. Int J Health Plann Manage. 2018;33(4):e1037-e49. DOI

VH1-69 Utilizing Antibodies Are Capable of Mediating Non-neutralizing Fc-Mediated Effector Functions Against the Transmitted/Founder gp120. Smith SA, Burton SL, Kilembe W, Lakhi S, Karita E, Price M, et al. Front Immunol. 2018;9:3163. DOI

Prediction of extended high viremia among newly HIV-1-infected persons in sub-Saharan Africa. Powers KA, Price MA, Karita E, Kamali A, Kilembe W, Allen S, et al. PLoS One. 2018;13(4):e0192785. DOI

Difficult decisions: Evaluating individual and couple-level fertility intentions and HIV acquisition among HIV serodiscordant couples in Zambia. Joseph Davey DL, Wall KM, Kilembe W, Khu NH, Brill I, Vwalika B, et al. PLoS One. 2018;13(1):e0189869. DOI

Evaluation of a multi-level intervention to improve postpartum intrauterine device services in Rwanda. Ingabire R, Nyombayire J, Hoagland A, Da Costa V, Mazzei A, Haddad L, et al. Gates Open Res. 2018;2(38):38. DOI

Bacterial vaginosis modifies the association between hormonal contraception and HIV acquisition. Haddad LB, Wall KM, Kilembe W, Vwalika B, Khu NH, Brill I, et al. AIDS. 2018;32(5):595-604. DOI

HLA Class I Downregulation by HIV-1 Variants from Subtype C Transmission Pairs. Ende Z, Deymier MJ, Claiborne DT, Prince JL, Monaco DC, Kilembe W, et al. J Virol. 2018;92(7):e01633-17. DOI

Fc-gamma receptor IIA and IIIA variants in two African cohorts: Lack of consistent impact on heterosexual HIV acquisition, viral control, and disease progression. Connolly S, Wall KM, Tang J, Yu T, Kilembe W, Kijak G, et al. Virology. 2018;525:132-42. DOI

2017

Pregnancy and HIV Disease Progression in an Early Infection Cohort from Five African Countries. Wall KM, Rida W, Haddad LB, Kamali A, Karita E, Lakhi S, et al. Epidemiology. 2017;28(2):224-32. DOI

Sustained effect of couples' HIV counseling and testing on risk reduction among Zambian HIV serodiscordant couples. Wall KM, Kilembe W, Vwalika B, Haddad LB, Lakhi S, Onwubiko U, et al. Sex Transm Infect. 2017;93(4):259-66. DOI

Optimizing Prevention of HIV and Unplanned Pregnancy in Discordant African Couples. Wall KM, Kilembe W, Vwalika B, Haddad LB, Khu NH, Brill I, et al. Journal of women's health (2002). 2017;26(8):900-10. DOI

Risk of heterosexual HIV transmission attributable to sexually transmitted infections and non-specific genital inflammation in Zambian discordant couples, 1994-2012. Wall KM, Kilembe W, Vwalika B, Haddad LB, Hunter E, Lakhi S, et al. Int J Epidemiol. 2017;46(5):1593-606. DOI

Incentives to improve couples' HIV testing uptake and cost-effectiveness. Wall K, Allen S. Lancet Glob Health. 2017;5(9):e847-e8. DOI

HIV Incidence and Predictors of HIV Acquisition From an Outside Partner in Serodiscordant Couples in Lusaka, Zambia. Joseph Davey DL, Wall KM, Kilembe W, Naw HK, Brill I, Vwalika B, et al. Journal of acquired immune deficiency syndromes (1999). 2017;76(2):123-31. DOI

Risky Sex and HIV Acquisition Among HIV Serodiscordant Couples in Zambia, 2002-2012: What Does Alcohol Have To Do With It? Joseph Davey D, Kilembe W, Wall KM, Khu NH, Brill I, Vwalika B, et al. AIDS and behavior. 2017;21(7):1892-903. DOI

Transitioning couple's voluntary HIV counseling and testing (CVCT) from stand-alone weekend services into routine antenatal and VCT services in government clinics in Zambia's two largest cities. Inambao M, Kilembe W, Canary LA, Czaicki NL, Kakungu-Simpungwe M, Chavuma R, et al. PLoS One. 2017;12(10):e0185142. DOI

2016

Hormonal Contraceptive Use Among HIV-Positive Women and HIV Transmission Risk to Male Partners, Zambia, 1994-2012. Wall KM, Kilembe W, Vwalika B, Ravindhran P, Khu NH, Brill I, et al. J Infect Dis. 2016;214(7):1063-71. DOI

Hormonal Contraception, Pregnancy, Breastfeeding, and Risk of HIV Disease Progression Among Zambian Women. Wall KM, Kilembe W, Haddad L, Vwalika B, Lakhi S, Khu NH, et al. Journal of acquired immune deficiency syndromes (1999). 2016;71(3):345-52. DOI

Acceptability of Couples' Voluntary HIV Testing Among HIV-infected Patients in Care and Their HIV-negative Partners in the United States. Wall KM, Canary L, Workowski K, Lockard A, Jones J, Sullivan P, et al. The open AIDS journal. 2016;10:1-13. DOI

Diversification in the HIV-1 Envelope Hyper-variable Domains V2, V4, and V5 and Higher Probability of Transmitted/Founder Envelope Glycosylation Favor the Development of Heterologous Neutralization Breadth. Smith SA, Burton SL, Kilembe W, Lakhi S, Karita E, Price M, et al. PLoS pathogens. 2016;12(11):e1005989. DOI

Dynamics and Correlates of CD8 T-Cell Counts in Africans with Primary Human Immunodeficiency Virus Type 1 Infection. Prentice HA, Lu H, Price MA, Kamali A, Karita E, Lakhi S, et al. J Virol. 2016;90(22):10423-30. DOI

Balance between transmitted HLA preadapted and nonassociated polymorphisms is a major determinant of HIV-1 disease progression. Monaco DC, Dilernia DA, Fiore-Gartland A, Yu T, Prince JL, Dennis KK, et al. The Journal of experimental medicine. 2016;213(10):2049-63. DOI

Broadly Neutralizing Antibody Responses in a Large Longitudinal Sub-Saharan HIV Primary Infection Cohort. Landais E, Huang X, Havenar-Daughton C, Murrell B, Price MA, Wickramasinghe L, et al. PLoS pathogens. 2016;12(1):e1005369. DOI

Promotion of couples' voluntary HIV counseling and testing: a comparison of influence networks in Rwanda and Zambia. Kelley AL, Hagaman AK, Wall KM, Karita E, Kilembe W, Bayingana R, et al. BMC public health. 2016;16:744. DOI

Implementation and Operational Research: Evolution of Couples' Voluntary Counseling and Testing for HIV in Rwanda: From Research to Public Health Practice. Karita E, Nsanzimana S, Ndagije F, Wall KM, Mukamuyango J, Mugwaneza P, et al. Journal of acquired immune deficiency syndromes (1999). 2016;73(3):e51-e8. DOI

Impact of pre-adapted HIV transmission. Carlson JM, Du VY, Pfeifer N, Bansal A, Tan VY, Power K, et al. Nature medicine. 2016;22(6):606-13. DOI

2015

Transmitted virus fitness and host T cell responses collectively define divergent infection outcomes in two HIV-1 recipients. Yue L, Pfafferott KJ, Baalwa J, Conrod K, Dong CC, Chui C, et al. PLoS pathogens. 2015;11(1):e1004565. DOI

Hormonal contraception does not increase women's HIV acquisition risk in Zambian discordant couples, 1994-2012. Wall KM, Kilembe W, Vwalika B, Htee Khu N, Brill I, Chomba E, et al. Contraception. 2015;91(6):480-7. DOI

Authors' reply: Hormonal contraceptives and HIV: Hazards of pronouncing "negative" studies with low power. Wall KM, Kilembe W, Vwalika B, Haddad L, Allen S. Contraception. 2015;92(3):277. DOI

Implementation of an electronic fingerprint-linked data collection system: a feasibility and acceptability study among Zambian female sex workers. Wall KM, Kilembe W, Inambao M, Chen YN, McHoongo M, Kimaru L, et al. Globalization and health. 2015;11:27. DOI

CD4:CD8 lymphocyte ratio as a quantitative measure of immunologic health in HIV-1 infection: findings from an African cohort with prospective data. Tang J, Li X, Price MA, Sanders EJ, Anzala O, Karita E, et al. Frontiers in microbiology. 2015;6:670. DOI

Immunogenetic influences on acquisition of HIV-1 infection: consensus findings from two African cohorts point to an enhancer element in IL19 (1q32.2). Li X, Zhang K, Pajewski NM, Brill I, Prentice HA, Shrestha S, et al. Genes and immunity. 2015;16(3):213-20. DOI

Implementation of couples' voluntary HIV counseling and testing services in Durban, South Africa. Kilembe W, Wall KM, Mokgoro M, Mwaanga A, Dissen E, Kamusoko M, et al. BMC public health. 2015;15:601. DOI

Knowledge of HIV serodiscordance, transmission, and prevention among couples in Durban, South Africa. Kilembe W, Wall KM, Mokgoro M, Mwaanga A, Dissen E, Kamusoko M, et al. PLoS One. 2015;10(4):e0124548. DOI

High Transmitter CD4+ T-Cell Count Shortly after the Time of Transmission in a Study of African Serodiscordant Couples. Karita E, Price MA, Lakhi S, Kilembe W, Kamali A, Ruzagira E, et al. PLoS One. 2015;10(8):e0134438. DOI

Creating an African HIV clinical research and prevention trials network: HIV prevalence, incidence and transmission. Kamali A, Price MA, Lakhi S, Karita E, Inambao M, Sanders EJ, et al. PLoS One. 2015;10(1):e0116100. DOI

HLA Class-II Associated HIV Polymorphisms Predict Escape from CD4+ T Cell Responses. Erdmann N, Du VY, Carlson J, Schaefer M, Jureka A, Sterrett S, et al. PLoS pathogens. 2015;11(8):e1005111. DOI

Multiplexed highly-accurate DNA sequencing of closely-related HIV-1 variants using continuous long reads from single molecule, real-time sequencing. Dilernia DA, Chien JT, Monaco DC, Brown MP, Ende Z, Deymier MJ, et al. Nucleic acids research. 2015;43(20):e129. DOI

Heterosexual Transmission of Subtype C HIV-1 Selects Consensus-Like Variants without Increased Replicative Capacity or Interferon-alpha Resistance. Deymier MJ, Ende Z, Fenton-May AE, Dilernia DA, Kilembe W, Allen SA, et al. PLoS pathogens. 2015;11(9):e1005154. DOI

Replicative fitness of transmitted HIV-1 drives acute immune activation, proviral load in memory CD4+ T cells, and disease progression. Claiborne DT, Prince JL, Scully E, Macharia G, Micci L, Lawson B, et al. Proc Natl Acad Sci U S A. 2015;112(12):E1480-9. DOI