Biochemistry
| Principal Investigator | Award | Sponsor Name | Proposal Type | Award Period |
| Avci, Fikri Y | Pn3Pase as an Effective Enzyme Therapeutic for Streptococcus Pneumoniae type 3 Infection | PNEUMOTACTIX | New | 17-NOV-23 - 30-JUN-24 |
| Conn, Graeme Leslie | Mechanisms and biological functions of SPOUT methyltransferases | OHIO STATE UNIVERSITY | New | 01-SEP-23 - 31-JUL-24 |
| Draganova, Elizabeth Bennett | Mechanisms of Conformational Dynamics and Inhibition of the HSV-1 Nuclear Egress Complex | NIH NATL INST OF ALLERGY AND INFECTIOUS | Supplemental | 20-MAR-23 - 28-FEB-25 |
| Draganova, Elizabeth Bennett | Under Pressure: Biophysical Mapping of Herpesvirus Capsid Assembly and Genome Packaging | NIH NATL INST OF GENERAL MEDICAL SCIENCE | New | 18-SEP-23 - 31-AUG-26 |
| Ghalei, Homa | Biogenesis of macromolecular machines for post-transcriptional regulation of translation | NIH NATL INST OF GENERAL MEDICAL SCIENCE | Supplemental | 17-AUG-20 - 31-JUL-25 |
| Liang, Bo | Functions and structures of the Nipah virus polymerase | UNIVERSITY OF TEXAS MEDICAL BRANCH | New | 01-MAY-23 - 30-APR-24 |
| Liang, Bo | SARS-CoV-2 Viral and Receptor Protein Production and Cryogenic Electron Microscopy | CENTERS FOR DISEASE CONTROL | New | 31-AUG-23 - 30-AUG-24 |
| Liang, Bo | Production of Highly Purified Proteins and Structure Determination of Antigen-ant | CENTERS FOR DISEASE CONTROL | New | 25-AUG-23 - 24-AUG-24 |
| Liu, Xu | Molecular mechanisms of Vamorolone action on X-linked dilated cardiomyopathy | NATL AMERICAN HEART ASSOCIATION | New | 01-JUL-21 - 30-JUN-24 |
| Ortlund, Eric A. | Them1 Inhibitors for the Management of Non-Alcoholic Fatty Liver Disease | BRIGHAM AND WOMENS HOSPITAL | New | 01-JUL-23 - 30-APR-28 |
| Ortlund, Eric A. | Targeting the orphan nuclear receptor LRH-1 with small molecules | NIH NATL INST OF DIABETES DIGESTIVE AND | New | 01-SEP-23 - 31-JUL-27 |
| Ortlund, Eric A. | Them1-Mediated Metabolic Regulation and Pathogenic Role in NAFLD | BRIGHAM AND WOMENS HOSPITAL | Continuation | 01-JUL-23 - 30-JUN-24 |
| Seyfried, Nicholas T. | Investigating the role of TMEM106b genetics and pathology in Alzheimer's disease | MAYO CLINIC | New | 22-SEP-23 - 31-AUG-28 |
| Seyfried, Nicholas T. | Risk Factors, Pathology, and Clinical Expressions of AD | RUSH UNIVERSITY MEDICAL CENTER | Continuation | 15-JUL-19 - 30-APR-24 |
| Seyfried,Nicholas T. | Generation, Characterization, and Validation of Marmoset Models of Alzheimer's Dis | UNIVERSITY OF PITTSBURGH | Continuation | 01-SEP-22 - 31-AUG-27 |
| Seyfried, Nicholas T. | The IU/JAX Alzheimer's Disease Precision Models Center | INDIANA UNIVERSITY | Continuation | 30-SEP-22 - 31-AUG-27 |
| Song, Xuezheng | Next Generation Glycan Microarray using DNA-coded glycans and Next Generation Sequencing (NGS) | NIH NATL INST OF GENERAL MEDICAL SCIENCE | Continuation | 15-SEP-20 - 31-JUL-24 |
| Sundberg, Eric John | Deciphering the IgG glycosylation code of Alzheimer's Disease | NIH NATL INSTITUTE ON AGING | New | 01-FEB-24 - 31-JAN-29 |
| Sundberg, Eric John | Engineering mono-fucosylated IgGs to fine-tune antibody-mediated effector functions | NIH NATL INST OF ALLERGY AND INFECTIOUS | Continuation | 03-FEB-23 - 31-JAN-25 |
Cell Biology
| Principal Investigator | Award | Sponsor Name | Proposal Type | Award Period |
| Bassell, Gary J | Single-Molecule Imaging of Ubiquitination Dynamics in Neurons | NIH NATL INST OF NEUROLOGICAL DISORDERS | New | 15-SEP-23 - 31-AUG-25 |
| Bassell, Gary J | Fragile X messenger ribonucleoprotein-1 mediated regulation of the Clathrin-Associated Adaptor Complex Protein-2 (AP2) | NIH NATL INSTITUTE OF MENTAL HEALTH | New | 01-JAN-24 - 31-DEC-24 |
| Emanuel, Alan J | Contextual Representation of Tactile Information in Mouse Primary Somatosensory Cortex | NIH NATL INST OF NEUROLOGICAL DISORDERS | Continuation | 01-JAN-23 - 31-DEC-25 |
| English, Arthur W | Role of Stress Granule Protein Aggregation in Axon Regeneration | UNIVERSITY OF SOUTH CAROLINA | Continuation | 01-JUL-20 - 30-JUN-24 |
| Faundez, Victor | Systems Biology of Rett Syndrome Gene Therapy Outcomes | RETT SYNDROME RESEARCH FOUNDATION | Supplemental | 01-NOV-21 - 31-OCT-24 |
| Faundez, Victor | Mitochondrial Alzheimer's Risk Factors Control APOE Expression and Secretion | CURE ALZHEIMERS FUND | New | 01-MAR-24 - 28-FEB-25 |
| Faundez, Victor | Systemic Molecular Phenotypes in Koolen-de Vries Syndrome | KOOLEN-DE VRIES SYNDROME FOUNDATION | New | 01-JAN-24 - 31-DEC-24 |
| Hailstock, Taylor Simone | Characterization of orb2-dependent microcephaly in Drosophila | HOWARD HUGHES MEDICAL INSTITUTE | New | 01-SEP-23 - 31-AUG-26 |
| Kosti, Adam George | Mechanisms of microRNA dysregulation in Fragile X Syndrome | NIH NATL INSTITUTE OF MENTAL HEALTH | New | 13-SEP-23 - 31-AUG-26 |
| Lane, Alicia R | Metabolic Mechanisms of Copper-Dependent Neurodegeneration and Excitability in Menkes Disease | NIH NATL INST OF NEUROLOGICAL DISORDERS | New | 06-APR-22 - 05-APR-25 |
| Li, Yaqing | Role of SCI-induced spontaneous afferents activity in sympathetic function and col | CRAIG H NEILSEN FOUNDATION | New | 01-JUL-23 - 30-JUL-25 |
| Myers, Kenneth R | Coordinating synaptic actin and translational control | WHITEHALL FOUNDATION | New | 01-SEP-23 - 31-AUG-26 |
| Noble, Donald James | Respiratory rate conditioning for pain control after spinal cord injury | CRAIG H NEILSEN FOUNDATION | New | 31-JUL-23 - 30-JUL-25 |
| Pant, Devesh Chandra | Investigation of ALS caused by mutant KIF5A | MUSCULAR DYSTROPHY ASSOCIATION | New | 01-SEP-23 - 31-AUG-26 |
| Pant, Devesh Chandra | Role of altered sphingolipids in the pathophysiology of ALS | LIVE LIKE LOU FOUNDATON | New | 15-JAN-24 - 14-JAN-25 |
| Perreault, Marie-Claude | Communication, Coordination, and Control of Neuromechanical Systems (C3NS) | CASE WESTERN RESERVE UNIVERSITY | Continuation | 01-SEP-20 - 31-AUG-25 |
| Sampson, Timothy Robert | Interaction of Pyrethroid Exposure and the Microbiome on Parkinson's Disease related Pathologies | NIH NATL INST OF ENVIRONMENTAL HLTH SCIE | Continuation | 09-FEB-22 - 30-NOV-26 |
| Singleton, Kaela Shanice | Integrity and localization of Mitochondria in Menkes Disease Pathogenesis | NIH NATL INST OF NEUROLOGICAL DISORDERS | Continuation | 15-JUL-20 - 31-JUL-23 |
| Ward, Patricia J | Sympathetic Function in Neural Injuries | NIH NATL INST OF NEUROLOGICAL DISORDERS | Continuation | 23-SEP-21 - 31-AUG-24 |
| Zhang, Shirley | Circadian rhythm regulation of blood-brain barrier transport and inflammation | NIH NATL INST OF NEUROLOGICAL DISORDERS | New | 01-DEC-23 - 30-NOV-25 |
| Zhang, Shirley | Determining the importance of temporal regulation of the blood-brain barrier | NIH NATL HEART LUNG AND BLOOD INSTITUE | Continuation | 01-SEP-21 - 31-AUG-24 |
Microbiology and Immunology
| Principal Investigator | Award | Sponsor Name | Proposal Type | Award Period |
| Ahmed, Rafi | Cell mediated immunity assays for B and T cell responses to influenza vaccination | CENTERS FOR DISEASE CONTROL | New | 11-SEP-23 - 10-SEP-24 |
| Ahmed, Rafi | Rapid identification of human antibodies recognizing influenza hemagglutinin | CENTERS FOR DISEASE CONTROL | New | 11-SEP-23 - 10-SEP-25 |
| Ahmed, Rafi | Biond Biologics Collaboration - sCD28 | BIOND BIOLOGICS | New | 14-SEP-23 - 13-AUG-24 |
| Ahmed, Rafi | Therapeutic use of CUE-100 series IST (immuno-STATTM) platform to enhance CD8 | CUE BIOPHARMA | New | 01-OCT-23 - 30-SEP-25 |
| Ahmed, Rafi | Emory CESDEP: Cellular assays for quantitating CD4 and CD8 T cell responses | LEIDOS BIOMEDICAL RESEARCH | New | 30-NOV-23 - 30-NOV-24 |
| Ahmed, Rafi | Isolation and Characterization of Human Monoclonal Antibodies Against Anthrax | USA MED RESEARCH ACQ ACTIVITY | New | 25-SEP-23 - 24-SEP-24 |
| Ahmed, Rafi | Vaccine Induced Immunity in the Young and Aged | NIH NATL INST OF ALLERGY AND INFECTIOUS | Supplemental | 01-MAY-19 - 30-APR-24 |
| Ahmed,Rafi | Consortium for HIV/AIDS Vaccine Development | SCRIPPS RESEARCH INSTITUTE | Continuation | 01-JUL-19 - 30-JUN-24 |
| Ahmed, Rafi | Costimulation and regulation of anti-viral immunity | HARVARD UNIVERSITY | Continuation | 01-SEP-19 - 31-AUG-24 |
| Ahmed, Rafi | Mt. Sinai - Emory Multi-institutional CIVIC | MOUNT SINAI SCHOOL OF MEDICINE | Continuation | 10-SEP-19 - 09-SEP-24 |
| Basu Thakur,Poulami | CDC IPA: POULAMI BASU THAKUR | CENTERS FOR DISEASE CONTROL | Continuation | 30-JUN-21 - 29-JUN-24 |
| Boss, Jeremy M | TLR7 and TLR9-directed plasma cell formation: Dissecting the molecular basis for their differential dependence on IFN-induced signals | UNIVERSITY OF ALABAMA BIRMINGHAM | Continuation | 10-JUL-20 - 30-JUN-24 |
| Davis, Carl W | Consortium for Immunotherapeutics against Emerging Viral Threats. | LA JOLLA INSTITUTE FOR IMMUNOLOGY | Continuation | 01-MAY-19 - 30-APR-24 |
| Lakdawala, Seema | NIAID Centers of Excellence for Influenza Research and Response | UNIVERSITY OF PENNSYLVANIA | Continuation | 01-AUG-22 - 31-MAR-24 |
| Lakdawala, Seema | Role of preexisting immunity on airborne transmission of influenza viruses | NIH NATL INST OF ALLERGY AND INFECTIOUS | Continuation | 01-FEB-23 - 31-JAN-27 |
| Lakdawala, Seema | Assessment of the role of pre-existing immunity in the emergence of H5N1 and H9N2 | UNIVERSITY OF PITTSBURGH | New | 18-SEP-23 - 17-SEP-25 |
| LaRock, Christopher N | Proteolytic regulation of the Streptococcus pyogenes cell surface | NIH NATL INST OF ALLERGY AND INFECTIOUS | Continuation | 15-JAN-21 - 31-DEC-25 |
| Lowen, Anice Carmen | Impact of intra-host population structure on influenza virus antigenic evolution | NIH NATL INST OF ALLERGY AND INFECTIOUS | Continuation | 09-DEC-21 - 30-NOV-26 |
| Lowen, Anice Carmen | Development of Oncolytic Reovirus for Triple-Negative Breast Cancer | NIH NATL INST OF ALLERGY AND INFECTIOUS | Continuation | 10-JAN-20 - 31-DEC-25 |
| Lowen, Anice Carmen | CEIRR: SARS-CoV-2 Research Activities | NIH NATL INST OF ALLERGY AND INFECTIOUS | Continuation | 01-APR-21 - 17-SEP-26 |
| Mattingly, Cameron LaRue Robinson | Duration and Function of Lung Tissue Resident CD8+ Memory T cells | NIH NATL HEART LUNG AND BLOOD INSTITUE | Continuation | 01-FEB-23 - 31-JAN-25 |
| Medina, Christopher Bernardo | Defining the unique classes of inhibitory receptor molecules during CD8+ T cell | HOWARD HUGHES MEDICAL INSTITUTE | Continuation | 01-OCT-22 - 30-SEP-24 |
| McBride, Shonna M | Genetic Mechanisms of Sporulation Induction in C. difficile | NIH NATL INST OF ALLERGY AND INFECTIOUS | Continuation | 01-FEB-21 - 31-JAN-26 |
| Raghunathan, Vedhika | Within and between host dynamics in influenza A virus antigenic evolution | NIH NATL INST OF ALLERGY AND INFECTIOUS | New F31 | 01-MAY-24 - 30-APR-27 |
| Scharer, Christopher David | Epigenetic instruction of memory B cell function and reactivation | NIH NATL INST OF ALLERGY AND INFECTIOUS | Continuation | 12-DEC-19 - 30-NOV-24 |
| Scharer, Christopher David | Mechanisms driving extrafollicular polyreactive B cell lineages in partial RAG | UNIVERSITY OF SOUTH FLORIDA | Continuation | 22-SEP-21 - 31-AUG-24 |
| Shafer, William M | FY21 CDC IPA Renewal Agreement | CENTERS FOR DISEASE CONTROL | Continuation | 15-SEP-21 - 14-SEP-24 |
Pharmacology and Chemical Biology
| Principal Investigator | Award | Sponsor Name | Proposal Type | Award Period |
| Dingledine, Raymond |
Probing the Protective Role of EZH2 in Epilepsy |
UNIVERSITY OF WISCONSIN-MADISON | Continuation | 01-AUG-19 - 31-MAY-24 |
| Golde, Todd Eliot | A consortium effort to translate therapies for neurological diseases | UNIVERSITY OF NORTH CAROLINA CHAPEL HILL | Continuation | 01-AUG-22 - 30-APR-25 |
| Hall, Randy A. | Disease-Associated Mutations and Ligand Activation of the Adhesion G Protein-Coupled Receptor ADGRB2 | NIH NATL INST OF NEUROLOGICAL DISORDERS | New | 15-SEP-23 - 31-AUG-25 |
| Hess, Ellen J | Neuronal Mechanisms underlying sex differences in dystonia | NIH NATL INST OF NEUROLOGICAL DISORDERS | Supplemental | 15-SEP-22 - 31-JUL-26 |
| Ivanov, Andrey Andreyevich | Predicting actionable cancer vulnerabilities enabled by mutant-directed protein-protein interactions | NIH NATL CANCER INSTITUTE | Continuation | 01-SEP-22 - 31-AUG-24 |
| Levites, Yona | Innervation of the knee and TMJ | UNIVERSITY OF FLORIDA | Continuation | 23-SEP-22 - 31-AUG-25 |
| Read, Renee D | Verteporfin as a YAP/TAZ inhibitor for treatment of glioblastoma | NIH NATL INST OF NEUROLOGICAL DISORDERS | New | 21-SEP-23 - 31-MAY-28 |
| Read, Renee D | Identifying and Testing Molecular Therapies for Schwannoma | US DEPARTMENT OF DEFENSE | New | 01-JUL-23 - 30-JUN-26 |
| Read, Renee D | Human Organoid Models for Pediatric High-Grade Gliomas | NIH NATL INST OF NEUROLOGICAL DISORDERS | New | 11-SEP-23 - 31-AUG-25 |
| Varvel, Nicholas H | Brain-invading monocytes promote the deleterious consequences of status epilepticus | NIH NATL INST OF NEUROLOGICAL DISORDERS | Continuation | 01-DEC-19 - 30-NOV-25 |