Sinefungin, a natural nucleoside analog of S-adenosyl methionine, impairs the pathogenicity of Candida albicans.
npj Antimicrobials and Resistance. Volume: 2(1):23. doi: 10.1038/s44259-024-00040-9.
09/01/2024 Authors: Nayak A, Khedri A, Chavarria A, Sanders K, Ghalei H, Khoshnevis S.
A biallelic variant of the RNA exosome gene, EXOSC4, associated with neurodevelopmental defects impairs RNA exosome function and translation.
J Biol Chem. Aug;300(8):107571. doi: 10.1016/j.jbc.2024.107571. Epub 2024 Jul 14. PubMed PMID: 39009343.
07/14/2024 Authors: Fasken MB, Leung SW, Cureton LA, Al-Awadi M, Al-Kindy A, van Hoof A, Khoshnevis S, Ghalei H, Al-Maawali A, Corbett AH.
The putative RNA helicase DDX1 associates with the nuclear RNA exosome and modulates RNA/DNA hybrids (R-loops).
J Biol Chem. Volume: 300(2):105646. doi: 10.1016/j.jbc.2024.105646. Epub 2024 Jan 12. PubMed PMID: 38219817.
02/01/2024 Authors: de Amorim JL, Leung SW, Haji-Seyed-Javadi R, Hou Y, Yu DS, Ghalei H, Khoshnevis S, Yao B, Corbett AH.
Comparative analyses of disease-linked missense mutations in the RNA exosome modeled in budding yeast reveal distinct functional consequences in translation.
bioRxiv. doi: 10.1101/2023.10.18.562946. PubMed PMID: 37904946.
10/19/2023 Authors: Sterrett MC, Cureton LA, Cohen LN, van Hoof A, Khoshnevis S, Fasken MB, Corbett AH, Ghalei H.
RNA structural probing of guanine and uracil nucleotides in yeast.
PLoS One;18(7):e0288070.
07/7/2023 Authors: Xiao K, Ghalei H#, Khoshnevis S#.
Studies of mutations of assembly factor Hit1 in budding yeast suggest translation defects as the molecular basis for PEHO syndrome.
J Biol Chem Volume: 298 Page(s): 102261
09/01/2022 Authors: Dreggors-Walker RE; Cohen LN; Khoshnevis S; Marchand V; Motorin Y; Ghalei H.
Ribosomal RNA 2'-O-methylations regulate translation by impacting ribosome dynamics.
Proc Natl Acad Sci U S A Volume: 119 Page(s): e2117334119
03/22/2022 Authors: Khoshnevis S#; Dreggors-Walker RE; Marchand V; Motorin Y; Ghalei H#.
Phosphorylation regulates arginine-rich RNA-binding protein solubility and oligomerization.
J Biol Chem Volume: 297 Page(s): 101306
11/01/2021 Authors: Kundinger SR; Dammer EB; Yin L; Hurst C; Shapley S; Ping L; Khoshnevis S; Ghalei H; Duong DM; Seyfried NT.
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