Publications

• An early precursor CD8+ T cell that adapts to acute or chronic viral infection.
  Nature Volume: 640 Page(s): 772 - 781
  04/01/2025 Authors: McManus DT; Valanparambil RM; Medina CB; Scharer CD; McGuire DJ; Sobierajska E; Hu Y; Chang DY; Wieland A; Lee J
• Anti-Ebola virus mAb 3A6 protects highly viremic animals from fatal outcome via binding GP(1,2) in a position elevated from the virion membrane.
  Nat Commun Volume: 16 Page(s): 1293
  02/03/2025 Authors: Hastie KM; Salie ZL; Ke Z; Halfmann PJ; DeWald LE; McArdle S; Griny A; Davidson E; Schendel SL; Hariharan C
• Meeting report: Considerations for trial design and endpoints in licensing therapeutic HPV16/18 vaccines to prevent cervical cancer.
  Vaccine Volume: 42 Page(s): 126100
  11/14/2024 Authors: Dull PM; Achilles SL; Ahmed R; Barnabas RV; Campos NG; Chirgwin K; Cohen JA; de Sanjos S; Doorbar J; Einstein MH
• Characteristics of Lung Cancer Patients With Asymptomatic or Undiagnosed SARS-CoV-2 Infections.
  Clin Lung Cancer Volume: 25 Page(s): 612 - 618
  11/01/2024 Authors: Somisetty M; Mack PC; Hsu C-Y; Huang Y; Gomez JE; Rodilla AM; Cagan J; Tavolacci SC; Carreo JM; Brody R
• Mechanical force regulates ligand binding and function of PD-1.
  Nat Commun Volume: 15 Page(s): 8339
  09/27/2024 Authors: Li K; Cardenas-Lizana P; Lyu J; Kellner AV; Li M; Cong P; Watson VE; Yuan Z; Ahn E; Doudy L
• Chronic viral infection alters PD-1 locus subnuclear localization in cytotoxic CD8+ Tcells.
  Cell Rep Volume: 43 Page(s): 114547
  08/27/2024 Authors: Sacristn C; Youngblood BA; Lu P; Bally APR; Xu JX; McGary K; Hewitt SL; Boss JM; Skok JA; Ahmed R
• Intensity-Modulated Reirradiation Therapy With Nivolumab in Recurrent or Second Primary Head and Neck Squamous Cell Carcinoma: A Nonrandomized Controlled Trial.
  JAMA Oncol Volume: 10 Page(s): 896 - 904
  07/01/2024 Authors: Saba NF; Wong SJ; Nasti T; McCook-Veal AA; McDonald MW; Stokes WA; Anderson AM; Ekpenyong A; Rupji M; Abousaud M
• Pembrolizumab and low-dose, single-fraction radiotherapy for patients with relapsed or refractory multiple myeloma: a prospective, single-centre, single-group, open-label, phase 2 pilot trial in the USA.
  Lancet Haematol Volume: 11 Page(s): e510 - e520
  07/01/2024 Authors: Khan MK; Nasti TH; Qian JY; Kleber TJ; Switchenko JM; Kaufman JL; Nooka AJ; Dhodapkar MV; Buchwald ZS; Obiekwe D
• Time-Dependent Effects of Clinical Interventions on SARS-CoV-2 Immunity in Patients with Lung Cancer.
  Vaccines (Basel) Volume: 12
  06/26/2024 Authors: Mack PC; Hsu C-Y; Rodilla AM; Gomez JE; Cagan J; Huang Y; Tavolacci S; Valanparambil RM; Rohs N; Brody R
• Platinum-Based Chemotherapy Attenuates the Effector Response of CD8 T Cells to Concomitant PD-1 Blockade.
  Clin Cancer Res Volume: 30 Page(s): 1833 - 1845
  05/01/2024 Authors: Mariniello A; Nasti TH; Chang DY; Hashimoto M; Malik S; McManus DT; Lee J; McGuire DJ; Cardenas MA; Umana P
• Michael Oldstone (1932-2023): Pioneer in viral pathogenesis, historian and author.
  Proc Natl Acad Sci U S A Volume: 121 Page(s): e2322335121
  04/09/2024 Authors: Ahmed R
• Harnessing CD8 T cell responses using PD-1-IL-2 combination therapy.
  Trends Cancer Volume: 10 Page(s): 332 - 346
  04/01/2024 Authors: Hashimoto M; Ramalingam SS; Ahmed R
• Severe disease during both primary and secondary dengue virus infections in pediatric populations.
  Nat Med Volume: 30 Page(s): 670 - 674
  03/01/2024 Authors: Aggarwal C; Ahmed H; Sharma P; Reddy ES; Nayak K; Singla M; Maheshwari D; Chawla YM; Panda H; Rai RC
• Reversible, tunable epigenetic silencing of TCF1 generates flexibility in the Tcell memory decision.
  Immunity Volume: 57 Page(s): 271 - 286.e13
  02/13/2024 Authors: Abadie K; Clark EC; Valanparambil RM; Ukogu O; Yang W; Daza RM; Ng KKH; Fathima J; Wang AL; Lee J
• Early generation of a precursor CD8 T cell that can adapt to acute or chronic viral infection.
  
  02/12/2024 Authors: McManus DT; Valanparambil RM; Medina CB; Hu Y; Scharer CD; Sobierajska E; Chang DY; Wieland A; Lee J; Nasti TH
• Functional impairment of "helpless" CD8 + memory T cells is transient and driven by prolonged but finite cognate antigen presentation.
  bioRxiv
  01/26/2024 Authors: van der Heide V; Davenport B; Cubitt B; Roudko V; Choo D; Humblin E; Jhun K; Angeliadis K; Dawson T; Furtado G
• Characterisation of clinical response and transcriptional profiling of proliferating CD8 T cells in the blood of cancer patients after PD-1 monotherapy or combination therapy.
  BMJ Oncol Volume: 3 Page(s): e000328
  01/01/2024 Authors: Obeng RC; Nasti TH; Martens K; Li P; Mariniello A; Chang DY; Eberhardt CS; McGuire D; Kissick H; Daugherty C
• Case Reports: Chemokine and Cytokine Profiling in Patients with Herpetic Uveitis.
  Int Med Case Rep J Volume: 17 Page(s): 1055 - 1061
  01/01/2024 Authors: Nguyen NV; Linderman SL; Fashina T; Devine M; Conrady CD; Shantha JG; Ahmed R; Yeh S
• Anti-Ebola virus mAb 3A6 with unprecedented potency protects highly viremic animals from fatal outcome and physically lifts its glycoprotein target from the virion membrane.
  Res Sq
  12/22/2023 Authors: Saphire E; Salie ZL; Ke Z; Halfmann P; DeWald LE; McArdle S; Grinyo A; Davidson E; Schendel S; Hariharan C
• Mitochondrial metabolic flexibility is critical for CD8+ T cell antitumor immunity.
  Sci Adv Volume: 9 Page(s): eadf9522
  12/08/2023 Authors: Chen C; Zheng H; Horwitz EM; Ando S; Araki K; Zhao P; Li Z; Ford ML; Ahmed R; Qu C-K
• Antibody responses to recombinant vesicular stomatitis virus-Zaire Ebolavirus vaccination for Ebola virus disease across doses and continents: 5-year durability.
  Clin Microbiol Infect Volume: 29 Page(s): 1587 - 1594
  12/01/2023 Authors: Huttner A; Agnandji ST; Engler O; Hooper JW; Kwilas S; Ricks K; Clements TL; Jonsdottir HR; Nakka SS; Rothenberger S
• The evolution and determinants of neutralization of potent head-binding antibodies against Ebola virus.
  Cell Rep Volume: 42 Page(s): 113366
  11/28/2023 Authors: Yu X; Hastie KM; Davis CW; Avalos RD; Williams D; Parekh D; Hui S; Mann C; Hariharan C; Takada A
• BA.5 bivalent booster vaccination enhances neutralization of XBB.1.5, XBB.1.16 and XBB.1.9 variants in patients with lung cancer.
  NPJ Vaccines Volume: 8 Page(s): 179
  11/21/2023 Authors: Valanparambil RM; Lai L; Johns MA; Davis-Gardner M; Linderman SL; McPherson TO; Chang A; Akhtar A; Gamarra ELB; Matia H
• Longitudinal nucleocapsid antibody testing reveals undocumented SARS-CoV-2 infections in patients with lung cancer.
  Cancer Cell Volume: 41 Page(s): 1838 - 1840
  11/13/2023 Authors: Rodilla AM; Valanparambil RM; Mack PC; Hsu C-Y; Cagan J; Tavolacci SC; Carreo JM; Brody R; Moore A; King JC
• Reciprocal transmission of activating and inhibitory signals and cell fate in regenerating Tcells.
  Cell Rep Volume: 42 Page(s): 113155
  10/31/2023 Authors: Wang PH; Washburn RS; Mariuzza DL; Lin W-HW; Gill AL; Ahmed R; Reiner SL
• Efficacy of mRNA-1273 and Novavax ancestral or BA.1 spike booster vaccines against SARS-CoV-2 BA.5 infection in nonhuman primates.
  Sci Immunol Volume: 8 Page(s): eadg7015
  10/27/2023 Authors: Routhu NK; Stampfer SD; Lai L; Akhtar A; Tong X; Yuan D; Chicz TM; McNamara RP; Jakkala K; Davis-Gardner ME
• Infants and young children generate more durable antibody responses to SARS-CoV-2 infection than adults.
  iScience Volume: 26 Page(s): 107967
  10/20/2023 Authors: Joshi D; Nyhoff LE; Zarnitsyna VI; Moreno A; Manning K; Linderman S; Burrell AR; Stephens K; Norwood C; Mantus G
• Characteristics and anatomic location of PD-1+TCF1+ stem-like CD8 T cells in chronic viral infection and cancer.
  Proc Natl Acad Sci U S A Volume: 120 Page(s): e2221985120
  10/10/2023 Authors: Im SJ; Obeng RC; Nasti TH; McManus D; Kamphorst AO; Gunisetty S; Prokhnevska N; Carlisle JW; Yu K; Sica GL
• Combination of PD-1 blockade and AZD5582 therapy in SIV plus monkeys
  Volume: 52 Page(s): 308 - 308
  10/01/2023 Authors: Yagnik B; Rahman SA; Freeman GJ; Ahmed R; Amara RR
• Light chain of a public SARS-CoV-2 class-3 antibody modulates neutralization against Omicron.
  Cell Rep Volume: 42 Page(s): 113150
  09/26/2023 Authors: Patel A; Kumar S; Lai L; Keen M; Valanparambil R; Chakravarthy C; Laughlin Z; Frank F; Cheedarla N; Verkerke HP
• mRNA vaccination boosts S-specific Tcell memory and promotes expansion of CD45RAint TEMRA-like CD8+ Tcells in COVID-19 recovered individuals.
  Cell Rep Med Volume: 4 Page(s): 101149
  08/15/2023 Authors: Mayer-Blackwell K; Ryu H; Codd AS; Parks KR; MacMillan HR; Cohen KW; Stewart TL; Seese A; Lemos MP; De Rosa SC
• Mechanical force regulates ligand binding and function of PD-1.
  bioRxiv
  08/15/2023 Authors: Li K; Cardenas-Lizana P; Kellner AV; Yuan Z; Ahn E; Lyu J; Li Z; Salaita K; Ahmed R; Zhu C
• PD-1 blockade increases the self-renewal of stem-like CD8 T cells to compensate for their accelerated differentiation into effectors.
  Sci Immunol Volume: 8 Page(s): eadg0539
  08/04/2023 Authors: Gill AL; Wang PH; Lee J; Hudson WH; Ando S; Araki K; Hu Y; Wieland A; Im S; Gavora A
• Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
  Structure Volume: 31 Page(s): 801 - 811.e5
  07/06/2023 Authors: Patel A; Kumar S; Lai L; Chakravarthy C; Valanparambil R; Reddy ES; Gottimukkala K; Bajpai P; Raju DR; Edara VV
• Low neutralizing activity of AZD7442 against current SARS-CoV-2 Omicron variants in patients with B-cell malignancies.
  Blood Adv Volume: 7 Page(s): 2459 - 2462
  06/13/2023 Authors: Chang A; Koff JL; Lai L; Orellana-Noia VM; Surati M; Leal AMK; Ellis ML; Wali B; Moreno A; Linderman SL
• Infants and young children generate more durable antibody responses to SARS-CoV-2 infection than adults.
  medRxiv
  04/11/2023 Authors: Joshi D; Nyhoff LE; Zarnitsyna VI; Moreno A; Manning K; Linderman S; Burrell AR; Stephens K; Norwood C; Mantus G
• Impaired SARS-CoV-2 Variant Neutralization and CD8+ T-cell Responses Following 3 Doses of mRNA Vaccines in Myeloma: Correlation with Breakthrough Infections.
  Blood Cancer Discov Volume: 4 Page(s): 106 - 117
  03/01/2023 Authors: Azeem MI; Nooka AK; Shanmugasundaram U; Cheedarla N; Potdar S; Manalo RJ; Moreno A; Switchenko JM; Cheedarla S; Doxie DB
• Risk Factors for Ebola Virus Persistence in Semen of Survivors in Liberia.
  Clin Infect Dis Volume: 76 Page(s): e849 - e856
  02/08/2023 Authors: Dyal J; Kofman A; Kollie JZ; Fankhauser J; Orone R; Soka MJ; Glaybo U; Kiawu A; Freeman E; Giah G
• Longitudinal Analysis of the Phenotype, Transcriptional Profile, and Anatomic Location of Memory CD8 T Cell Subsets after Acute Viral Infection.
  J Virol Volume: 97 Page(s): e0155622
  01/31/2023 Authors: Gill AL; Hudson WH; Valanparambil RM; Ahn E; McGuire DJ; Wieland A; McManus DT; Kissick HT; Akondy RS; Ahmed R
• mTOR regulates T cell exhaustion and PD-1-targeted immunotherapy response during chronic viral infection.
  J Clin Invest Volume: 133
  01/17/2023 Authors: Ando S; Perkins CM; Sajiki Y; Chastain C; Valanparambil RM; Wieland A; Hudson WH; Hashimoto M; Ramalingam SS; Freeman GJ
• Route of self-amplifying mRNA vaccination modulates the establishment of pulmonary resident memory CD8 and CD4 T cells.
  Sci Immunol Volume: 7 Page(s): eadd3075
  12/09/2022 Authors: Knzli M; O'Flanagan SD; LaRue M; Talukder P; Dileepan T; Stolley JM; Soerens AG; Quarnstrom CF; Wijeyesinghe S; Ye Y
• Antibody binding and neutralization of live SARS-CoV-2 variants including BA.4/5 following booster vaccination of patients with B-cell malignancies.
  Cancer Res Commun Volume: 2 Page(s): 1684 - 1692
  12/01/2022 Authors: Chang A; Akhtar A; Lai L; Orellana-Noia VM; Linderman SL; McCook-Veal AA; Switchenko JM; Saini M; Valanparambil RM; Blum KA
• Neutralizing antibody responses in patients hospitalized with SARS-CoV-2 Delta or Omicron infection.
  J Clin Invest Volume: 132
  12/01/2022 Authors: Linderman SL; Lai L; Bocangel Gamarra EL; Lau MS; Edupuganti S; Surie D; Tenforde MW; Chappell JD; Mohr NM; Gibbs KW
• Antibody Response to COVID-19 mRNA Vaccine in Patients With Lung Cancer After Primary Immunization and Booster: Reactivity to the SARS-CoV-2 WT Virus and Omicron Variant.
  J Clin Oncol Volume: 40 Page(s): 3808 - 3816
  11/20/2022 Authors: Valanparambil RM; Carlisle J; Linderman SL; Akthar A; Millett RL; Lai L; Chang A; McCook-Veal AA; Switchenko J; Nasti TH
• Persistent intraocular Ebola virus RNA is associated with severe uveitis in a convalescent rhesus monkey.
  Commun Biol Volume: 5 Page(s): 1204
  11/09/2022 Authors: Worwa G; Cooper TK; Yeh S; Shantha JG; Hischak AMW; Klim SE; Byrum R; Kurtz JR; Anthony SM; Aiosa NM
• Molecular basis of SARS-CoV-2 Omicron variant evasion from shared neutralizing antibody response.
  bioRxiv
  10/24/2022 Authors: Patel A; Kumar S; Lai L; Chakravarthy C; Valanparambil R; Reddy ES; Gottimukkala K; Bajpai P; Raju DR; Edara VV
• Structural insights for neutralization of Omicron variants BA.1, BA.2, BA.4, and BA.5 by a broadly neutralizing SARS-CoV-2 antibody.
  Sci Adv Volume: 8 Page(s): eadd2032
  10/07/2022 Authors: Kumar S; Patel A; Lai L; Chakravarthy C; Valanparambil R; Reddy ES; Gottimukkala K; Davis-Gardner ME; Edara VV; Linderman S
• The Quest to Eradicate HPV-Related Oropharyngeal Carcinoma: An Opportunity Not to Miss.
  J Natl Cancer Inst Volume: 114 Page(s): 1333 - 1337
  10/06/2022 Authors: Lalonde CS; Teng Y; Burtness BA; Ferris RL; Ahmed R; Saba NF
• TGF- regulates the stem-like state of PD-1+ TCF-1+ virus-specific CD8 T cells during chronic infection.
  J Exp Med Volume: 219
  10/03/2022 Authors: Hu Y; Hudson WH; Kissick HT; Medina CB; Baptista AP; Ma C; Liao W; Germain RN; Turley SJ; Zhang N
• Antibody Responses Against SARS-CoV-2 Variants after Booster Vaccination in Patients With B Cell Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia
  Volume: 22 Page(s): S281 - S282
  10/01/2022 Authors: Chang A; Lai L; Akhtar A; Linderman S; Orellana-Noia V; Saini M; Valanparambil R; Blum K; Allen P; Lechowicz M
• CLL-515 Antibody Responses Against SARS-CoV-2 Variants after Booster Vaccination in Patients With B Cell Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia.
  Clin Lymphoma Myeloma Leuk Volume: 22 Suppl 2 Page(s): S281 - S282
  10/01/2022 Authors: Chang A; Lai L; Akhtar A; Linderman S; Orellana-Noia V; Saini M; Valanparambil R; Blum K; Allen P; Lechowicz M
• PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program.
  Nature Volume: 610 Page(s): 173 - 181
  10/01/2022 Authors: Hashimoto M; Araki K; Cardenas MA; Li P; Jadhav RR; Kissick HT; Hudson WH; McGuire DJ; Obeng RC; Wieland A
• PD-1-cis IL-2R agonism yields better effectors from stem-like CD8+ T cells.
  Nature Volume: 610 Page(s): 161 - 172
  10/01/2022 Authors: Codarri Deak L; Nicolini V; Hashimoto M; Karagianni M; Schwalie PC; Lauener L; Varypataki EM; Richard M; Bommer E; Sam J
• Herpes simplex virus lymphadenitis is associated with tumor reduction in a patient with chronic lymphocytic leukemia.
  J Clin Invest Volume: 132
  09/15/2022 Authors: Chang A; Sholukh AM; Wieland A; Jaye DL; Carrington M; Huang M-L; Xie H; Jerome KR; Roychoudhury P; Greninger AL
• Humoral Responses Against SARS-CoV-2 and Variants of Concern After mRNA Vaccines in Patients With Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia.
  J Clin Oncol Volume: 40 Page(s): 3020 - 3031
  09/10/2022 Authors: Chang A; Akhtar A; Linderman SL; Lai L; Orellana-Noia VM; Valanparambil R; Ahmed H; Zarnitsyna VI; McCook-Veal AA; Switchenko JM
• Determinants of Neutralizing Antibody Response After SARS CoV-2 Vaccination in Patients With Myeloma.
  J Clin Oncol Volume: 40 Page(s): 3057 - 3064
  09/10/2022 Authors: Nooka AK; Shanmugasundaram U; Cheedarla N; Verkerke H; Edara VV; Valanparambil R; Kaufman JL; Hofmeister CC; Joseph NS; Lonial S
• PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques.
  Proc Natl Acad Sci U S A Volume: 119 Page(s): e2202148119
  08/16/2022 Authors: Velu V; Titanji K; Ahmed H; Shetty RD; Chennareddi LS; Freeman GJ; Ahmed R; Amara RR
• New epigenetic regulators of Tcell exhaustion.
  Cancer Cell Volume: 40 Page(s): 708 - 710
  07/11/2022 Authors: Kissick H; Ahmed R
• The Impact of Diabetes and Prediabetes on Prevalence of Mycobacterium tuberculosis Infection Among Household Contacts of Active Tuberculosis Cases in Ethiopia.
  Open Forum Infect Dis Volume: 9 Page(s): ofac323
  07/01/2022 Authors: Smith AGC; Kempker RR; Wassie L; Bobosha K; Nizam A; Gandhi NR; Auld SC; Magee MJ; Blumberg HM; Tuberculosis Research Unit: Role of Antigen Specific Responses in the Control of TB (TBRU-ASTRa) Study Group
• Contrasting behavior between the three human monocyte subsets in dengue pathophysiology.
  iScience Volume: 25 Page(s): 104384
  06/17/2022 Authors: Maheshwari D; Saini K; Singh P; Singla M; Nayak K; Aggarwal C; Chawla YM; Bajpai P; Kaur M; Gunisetty S
• Systemic and Laboratory Risk Factors for Retinopathy and Detection of Tear Film SARS-CoV-2 RNA
  Volume: 63
  06/01/2022 Authors: Shantha J; Fashina T; Simmons V; Randleman C; Ward L; Regueiro M; Linderman S; Drews-Botsch C; Ahmed R; Waggoner J
• Mission, Organization, and Future Direction of the Serological Sciences Network for COVID-19 (SeroNet) Epidemiologic Cohort Studies.
  Open Forum Infect Dis Volume: 9 Page(s): ofac171
  06/01/2022 Authors: Figueiredo JC; Hirsch FR; Kushi LH; Nembhard WN; Crawford JM; Mantis N; Finster L; Merin NM; Merchant A; Reckamp KL
• Distinct phenotypic states and spatial distribution of CD8+ Tcell clonotypes in human brain metastases.
  Cell Rep Med Volume: 3 Page(s): 100620
  05/17/2022 Authors: Sudmeier LJ; Hoang KB; Nduom EK; Wieland A; Neill SG; Schniederjan MJ; Ramalingam SS; Olson JJ; Ahmed R; Hudson WH
• Persistence of Virus-Specific Antibody after Depletion of Memory B Cells.
  J Virol Volume: 96 Page(s): e0002622
  05/11/2022 Authors: Langley WA; Wieland A; Ahmed H; Rasheed MAU; Davis CW; Sewatanon J; Mueller SN; Shlomchik MJ; Zarnitsyna VI; Antia R
• Pre-existing SARS-CoV-2 immunity influences potency, breadth, and durability of the humoral response to SARS-CoV-2 vaccination.
  Cell Rep Med Volume: 3 Page(s): 100603
  04/19/2022 Authors: Mantus G; Nyhoff LE; Edara V-V; Zarnitsyna VI; Ciric CR; Flowers MW; Norwood C; Ellis M; Hussaini L; Manning KE
• Asymmetric and non-stoichiometric glycoprotein recognition by two distinct antibodies results in broad protection against ebolaviruses.
  Cell Volume: 185 Page(s): 995 - 1007.e18
  03/17/2022 Authors: Milligan JC; Davis CW; Yu X; Ilinykh PA; Huang K; Halfmann PJ; Cross RW; Borisevich V; Agans KN; Geisbert JB
• In vivo mRNA delivery to virus-specific T cells by light-induced ligand exchange of MHC class I antigen-presenting nanoparticles.
  Sci Adv Volume: 8 Page(s): eabm7950
  02/25/2022 Authors: Su F-Y; Zhao QH; Dahotre SN; Gamboa L; Bawage SS; Silva Trenkle AD; Zamat A; Phuengkham H; Ahmed R; Santangelo PJ
• Transcriptomic signatures induced by the Ebola virus vaccine rVSVG-ZEBOV-GP in adult cohorts in Europe, Africa, and North America: a molecular biomarker study.
  Lancet Microbe Volume: 3 Page(s): e113 - e123
  02/01/2022 Authors: Vianello E; Gonzalez-Dias P; van Veen S; Engele CG; Quinten E; Monath TP; Medaglini D; VSV-EBOVAC Consortium; VSV-EBOPLUS Consortium; Santoro F
• Induction of thymic atrophy and loss of thymic output by type-I interferons during chronic viral infection.
  Virology Volume: 567 Page(s): 77 - 86
  02/01/2022 Authors: Dmoulins T; Baron M-L; Gauchat D; Kettaf N; Reed SJ; Charpentier T; Kalinke U; Lamarre A; Ahmed R; Skaly R-P
• Antibody response to SARS-CoV-2 mRNA vaccine in lung cancer patients: Reactivity to vaccine antigen and variants of concern.
  medRxiv
  01/23/2022 Authors: Valanparambil R; Carlisle J; Linderman S; Akthar A; Millett RL; Lai L; Chang A; McCook A; Switchenko J; Nasti T
• Evolving Views of Long Noncoding RNAs and Epigenomic Control of Lymphocyte State and Memory.
  Cold Spring Harb Perspect Biol Volume: 14
  01/04/2022 Authors: Morrison TA; Hudson WH; Chisolm DA; Kanno Y; Shih H-Y; Ahmed R; Henao-Mejia J; Hafner M; O'Shea JJ
• COVID-19 and the eye: Systemic and laboratory risk factors for retinopathy and detection of tear film SARS-CoV-2 RNA with a triplex RT-PCR assay.
  PLoS One Volume: 17 Page(s): e0277301
  01/01/2022 Authors: Shantha JG; Fashina T; Stittleburg V; Randleman C; Ward L; Regueiro M; Krakow D; Linderman SL; Drews-Botsch C; Ahmed R
• Characteristics of Ebola Virus Disease Survivor Blood and Semen in Liberia: Serology and Reverse Transcription Polymerase Chain Reaction (RT-PCR).
  Clin Infect Dis Volume: 73 Page(s): e3641 - e3646
  12/06/2021 Authors: Kofman A; Linderman S; Su K; Purpura LJ; Ervin E; Brown S; Morales-Betoulle M; Graziano J; Cannon DL; Klena JD
• Whole-lung low-dose radiation therapy (LD-RT) for non-intubated oxygen-dependent patients with COVID-19-related pneumonia receiving dexamethasone and/or remdesevir.
  Radiother Oncol Volume: 165 Page(s): 20 - 31
  12/01/2021 Authors: Hess CB; Eng TY; Nasti TH; Dhere VR; Kleber TJ; Switchenko JM; Weinberg BD; Rouphael N; Tian S; Rudra S
• Immunophenotyping and Transcriptional Profiling of Human Plasmablasts in Dengue.
  J Virol Volume: 95 Page(s): e0061021
  11/09/2021 Authors: Aggarwal C; Saini K; Reddy ES; Singla M; Nayak K; Chawla YM; Maheshwari D; Singh P; Sharma P; Bhatnagar P
• Influenza Immunization in the Context of Preexisting Immunity.
  Cold Spring Harb Perspect Med Volume: 11
  11/01/2021 Authors: Linderman SL; Ellebedy AH; Davis C; Eberhardt CS; Antia R; Ahmed R; Zarnitsyna VI
• Defining the Immune Cell Infiltrate of Brain Metastases Before and After Stereotactic Radiosurgery.
  Int J Radiat Oncol Biol Phys Volume: 111 Page(s): e233 - e234
  11/01/2021 Authors: Sudmeier LJ; Hudson W; Hoang KB; Nduom E; Shu HKG; Higgins KA; Olson JJ; Ahmed R
• CA209-9KY: Phase II Study of IMRT Re-Irradiation and Concurrent/Adjuvant Nivolumab (Nivo) in Patients With Loco Regionally Recurrent or Second Primary Head and Neck Squamous Cell Carcinoma (HNSCC) - Toxicity and Quality of Life (QoL) Results.
  Int J Radiat Oncol Biol Phys Volume: 111 Page(s): e361
  11/01/2021 Authors: Saba NF; Wong S; Stokes WA; Rupji M; Liu Y; Rudra S; Bates JE; Steuer C; Remick JS; Cummings K
• Reduced Intubation Rates Following Whole-Lung Low-Dose Radiation Therapy (LD-RT) in Patients With COVID-19-Related Pneumonia.
  Int J Radiat Oncol Biol Phys Volume: 111 Page(s): e41 - e42
  11/01/2021 Authors: Hess CB; Eng TY; Nasti T; Dhere VR; Kleber T; Switchenko J; Weinberg BD; Rouphael N; Tian S; Rudra S
• CA209-9KY: Phase II Study of IMRT Re-Irradiation and Concurrent/Adjuvant Nivolumab (Nivo) in Patients With Loco Regionally Recurrent or Second Primary Head and Neck Squamous Cell Carcinoma (HNSCC) - Toxicity and Quality of Life (QoL) Results
  Volume: 111 Page(s): E361 - E361
  11/01/2021 Authors: Saba NF; Wong S; Stokes WA; Rupji M; Liu Y; Rudra S; Bates JE; Steuer C; Remick JS; Cummings K
• Reduced Intubation Rates Following Whole-Lung Low-Dose Radiation Therapy (LD-RT) in Patients With COVID-19-Related Pneumonia
  Volume: 111 Page(s): E41 - E42
  11/01/2021 Authors: Hess CB; Eng TY; Nasti T; Dhere VR; Kleber T; Switchenko J; Weinberg BD; Rouphael N; Tian S; Rudra S
• Defining the Immune Cell Infiltrate of Brain Metastases Before and After Stereotactic Radiosurgery
  Volume: 111 Page(s): E233 - E234
  11/01/2021 Authors: Sudmeier LJ; Hudson W; Hoang KB; Nduom E; Shu HKG; Higgins KA; Olson JJ; Ahmed R
• CHARACTERIZATION OF TUMOR-INFILTRATING CD8+T CELLS IN BRAIN METASTASES
  Volume: 23 Page(s): 91 - 92
  11/01/2021 Authors: Sudmeier L; Hudson W; Hoang K; Nduom E; Neill S; Schniederjan M; Olson J; Ahmed R
• CORRELATIVE ANALYSIS OF BLOOD AND BIOPSY SAMPLES FROM A CLINICAL TRIAL OF HSP90 INHIBITION IN COMBINATION WITH PEMBROLIZUMAB REVEALS INCREASED INTRATUMORAL MYELOID CELL ACCUMULATION AFTER TREATMENT
  Volume: 9 Page(s): A434 - A434
  11/01/2021 Authors: Herting C; Zhang Y; Doxie D; Ware M; Alese O; Wu C; Akce M; Zaidi M; Ruggieri A; Dhodapkar M
• B cells and cancer.
  Cancer Cell Volume: 39 Page(s): 1293 - 1296
  10/11/2021 Authors: Engelhard V; Conejo-Garcia JR; Ahmed R; Nelson BH; Willard-Gallo K; Bruno TC; Fridman WH
• Dynamics and turnover of memory CD8 T cell responses following yellow fever vaccination.
  PLoS Comput Biol Volume: 17 Page(s): e1009468
  10/01/2021 Authors: Zarnitsyna VI; Akondy RS; Ahmed H; McGuire DJ; Zarnitsyn VG; Moore M; Johnson PLF; Ahmed R; Li KW; Hellerstein MK
• Response to Whole-Lung Low-Dose Radiation Therapy (LD-RT) Predicts Freedom from Intubation in Patients Receiving Dexamethasone And/or Remdesevir for COVID-19-Related Pneumonia
  Volume: 44 Page(s): S27 - S28
  10/01/2021 Authors: Hess C; Eng T; Nasti T; Dhere V; Kleber T; Switchenko J; Weinberg B; Rouphael N; Tian S; Rudra S
• Mature tertiary lymphoid structures in lung adenocarcinoma are associated with better progression free survival
  Volume: 156 Page(s): S149 - S149
  10/01/2021 Authors: Obeng R; Parihar V; Alexis D; Behera M; Owonikoko T; Pillai R; Ramalingam S; Sica G; Ahmed R
• PD-1 blockade and vaccination provide therapeutic benefit against SIV by inducing broad and functional CD8+ T cells in lymphoid tissue.
  Sci Immunol Volume: 6 Page(s): eabh3034
  09/10/2021 Authors: Rahman SA; Yagnik B; Bally AP; Morrow KN; Wang S; Vanderford TH; Freeman GJ; Ahmed R; Amara RR
• Functional HPV-specific PD-1+ stem-like CD8 T cells in head and neck cancer.
  Nature Volume: 597 Page(s): 279 - 284
  09/01/2021 Authors: Eberhardt CS; Kissick HT; Patel MR; Cardenas MA; Prokhnevska N; Obeng RC; Nasti TH; Griffith CC; Im SJ; Wang X
• Defining HPV-specific B cell responses in patients with head and neck cancer.
  Nature Volume: 597 Page(s): 274 - 278
  09/01/2021 Authors: Wieland A; Patel MR; Cardenas MA; Eberhardt CS; Hudson WH; Obeng RC; Griffith CC; Wang X; Chen ZG; Kissick HT
• Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and Tcells.
  Cell Rep Med Volume: 2 Page(s): 100354
  07/20/2021 Authors: Cohen KW; Linderman SL; Moodie Z; Czartoski J; Lai L; Mantus G; Norwood C; Nyhoff LE; Edara VV; Floyd K
• Immunological lessons from CD28 deficiency in humans.
  Cell Volume: 184 Page(s): 3595 - 3597
  07/08/2021 Authors: Wieland A; Ahmed R
• Longitudinal analysis shows durable and broad immune memory after SARS-CoV-2 infection with persisting antibody responses and memory B and T cells.
  medRxiv
  06/18/2021 Authors: Cohen KW; Linderman SL; Moodie Z; Czartoski J; Lai L; Mantus G; Norwood C; Nyhoff LE; Edara VV; Floyd K
• Evaluation of Cellular and Serological Responses to Acute SARS-CoV-2 Infection Demonstrates the Functional Importance of the Receptor-Binding Domain.
  J Immunol Volume: 206 Page(s): 2605 - 2613
  06/01/2021 Authors: Mantus G; Nyhoff LE; Kauffman RC; Edara VV; Lai L; Floyd K; Shi P-Y; Menachery VD; Edupuganti S; Scherer EM
• Characterization of neutralizing versus binding antibodies and memory B cells in COVID-19 recovered individuals from India.
  Virology Volume: 558 Page(s): 13 - 21
  06/01/2021 Authors: Nayak K; Gottimukkala K; Kumar S; Reddy ES; Edara VV; Kauffman R; Floyd K; Mantus G; Savargaonkar D; Goel PK
• Retinopathy and Systemic Disease Morbidity in Severe COVID-19.
  Ocul Immunol Inflamm Volume: 29 Page(s): 743 - 750
  05/19/2021 Authors: Shantha JG; Auld SC; Anthony C; Ward L; Adelman MW; Maier CL; Price KW; Jacob JT; Fashina T; Randleman C
• Mechanical plasticity of collagen directs branch elongation in human mammary gland organoids
  NATURE COMMUNICATIONS Volume: 12
  05/12/2021 Authors: Li K; Yuan Z; Lyu J; Ahn E; Davis SJ; Ahmed R; Zhu C
• PD-1 suppresses TCR-CD8 cooperativity during T-cell antigen recognition.
  Nat Commun Volume: 12 Page(s): 2746
  05/12/2021 Authors: Li K; Yuan Z; Lyu J; Ahn E; Davis SJ; Ahmed R; Zhu C
• Neutralizing Antibodies Against SARS-CoV-2 Variants After Infection and Vaccination.
  JAMA Volume: 325 Page(s): 1896 - 1898
  05/11/2021 Authors: Edara VV; Hudson WH; Xie X; Ahmed R; Suthar MS
• Diminished monocyte response in severe COVID-19 patients
  Volume: 206
  05/01/2021 Authors: Davis-Gardner ME; Edara V; Lai L; Jin F; Floyd K; Nyhoff L; Mantus G; Adelman M; Pellegrini K; Chirkova T
• Infection- and vaccine-induced antibody binding and neutralization of the B.1.351 SARS-CoV-2 variant.
  Cell Host Microbe Volume: 29 Page(s): 516 - 521.e3
  04/14/2021 Authors: Edara VV; Norwood C; Floyd K; Lai L; Davis-Gardner ME; Hudson WH; Mantus G; Nyhoff LE; Adelman MW; Fineman R
• Auto-antibodies to type I IFNs can underlie adverse reactions to yellow fever live attenuated vaccine.
  J Exp Med Volume: 218
  04/05/2021 Authors: Bastard P; Michailidis E; Hoffmann H-H; Chbihi M; Le Voyer T; Rosain J; Philippot Q; Seeleuthner Y; Gervais A; Materna M
• Immunomodulatory Low-Dose Whole-Lung Radiation for Patients with Coronavirus Disease 2019-Related Pneumonia.
  Int J Radiat Oncol Biol Phys Volume: 109 Page(s): 867 - 879
  03/15/2021 Authors: Hess CB; Nasti TH; Dhere VR; Kleber TJ; Switchenko JM; Buchwald ZS; Stokes WA; Weinberg BD; Rouphael N; Steinberg JP
• Reduced binding and neutralization of infection- and vaccine-induced antibodies to the B.1.351 (South African) SARS-CoV-2 variant.
  bioRxiv
  02/22/2021 Authors: Edara VV; Norwood C; Floyd K; Lai L; Davis-Gardner ME; Hudson WH; Mantus G; Nyhoff LE; Adelman MW; Fineman R
• Infection and mRNA-1273 vaccine antibodies neutralize SARS-CoV-2 UK variant.
  medRxiv
  02/05/2021 Authors: Edara VV; Floyd K; Lai L; Gardner M; Hudson W; Piantadosi A; Waggoner JJ; Babiker A; Ahmed R; Xie X
• Viral Immunity and Vaccines in Hematologic Malignancies: Implications for COVID-19.
  Blood Cancer Discov Volume: 2 Page(s): 9 - 12
  01/01/2021 Authors: Dhodapkar MV; Dhodapkar KM; Ahmed R
• Heat Shock Protein-90 Inhibition Alters Activation of Pancreatic Stellate Cells and Enhances the Efficacy of PD-1 Blockade in Pancreatic Cancer.
  Mol Cancer Ther Volume: 20 Page(s): 150 - 160
  01/01/2021 Authors: Zhang Y; Ware MB; Zaidi MY; Ruggieri AN; Olson BM; Komar H; Farren MR; Nagaraju GP; Zhang C; Chen Z
• Low-dose whole-lung radiation for COVID-19 pneumonia: Planned day 7 interim analysis of a registered clinical trial.
  Cancer Volume: 126 Page(s): 5109 - 5113
  12/01/2020 Authors: Hess CB; Buchwald ZS; Stokes W; Nasti TH; Switchenko JM; Weinberg BD; Steinberg JP; Godette KD; Murphy D; Ahmed R
• Immunomodulatory Low-Dose Whole-Lung Radiation for Patients with COVID-19-Related Pneumonia.
  Int J Radiat Oncol Biol Phys Volume: 108 Page(s): 1401
  12/01/2020 Authors: Hess CB; Buchwald ZS; Stokes WA; Nasti T; Switchenko J; Weinberg BD; Rouphael N; Steinberg JP; Godette KD; Murphy DJ
• INVESTIGATING THE CLINICAL SAFETY, EFFICACY, AND IMMUNE MODULATION OF COMBINED XL888 AND PEMBROLIZUMAB IN METASTATIC GASTROINTESTINAL MALIGNANCIES
  Volume: 8 Page(s): A202 - A203
  11/01/2020 Authors: Herting C; Zhang Y; Doxie D; Farren M; Ware M; Alese O; Wu C; Shaib W; Akce M; Zaidi M
• Influenza vaccine-induced human bone marrow plasma cells decline within a year after vaccination.
  Science Volume: 370 Page(s): 237 - 241
  10/09/2020 Authors: Davis CW; Jackson KJL; McCausland MM; Darce J; Chang C; Linderman SL; Chennareddy C; Gerkin R; Brown SJ; Wrammert J
• Tumor-draining lymph node is important for a robust abscopal effect stimulated by radiotherapy.
  J Immunother Cancer Volume: 8
  10/01/2020 Authors: Buchwald ZS; Nasti TH; Lee J; Eberhardt CS; Wieland A; Im SJ; Lawson D; Curran W; Ahmed R; Khan MK
• DNA/MVA Therapeutic Vaccination Induces Robust Polyfunctional SIV-Specific T-Cell Response and Antigen Recognition Breadth in Chronically SIVmac239-Infected Rhesus Macaques Under ART
  Volume: 49 Page(s): 261 - 261
  10/01/2020 Authors: Rahman SA; Yagnik B; Bally AP; Morrow K; Freeman GJ; Ahmed R; Amara RR
• T Cell Receptor Diversity and Lineage Relationship between Virus-Specific CD8 T Cell Subsets during Chronic Lymphocytic Choriomeningitis Virus Infection.
  J Virol Volume: 94
  09/29/2020 Authors: Chang YM; Wieland A; Li Z-R; Im SJ; McGuire DJ; Kissick HT; Antia R; Ahmed R
• Low-dose whole-lung radiation for COVID-19 pneumonia: Planned day-7 interim analysis of a registered clinical trial.
  Volume: 26
  09/01/2020 Authors: Hess CB; Buchwald ZS; Stokes W; Nasti TH; Switchenko JM; Weinberg BD; Steinberg JP; Godette KD; Murphy D; Ahmed R
• Exosome-Containing Preparations From Postirradiated Mouse Melanoma Cells Delay Melanoma Growth InVivo by a Natural Killer Cell-Dependent Mechanism.
  Int J Radiat Oncol Biol Phys Volume: 108 Page(s): 104 - 114
  09/01/2020 Authors: Jella KK; Nasti TH; Li Z; Lawson DH; Switchenko JM; Ahmed R; Dynan WS; Khan MK
• Adjuvanted H5N1 influenza vaccine enhances both cross-reactive memory B cell and strain-specific naive B cell responses in humans.
  Proc Natl Acad Sci U S A Volume: 117 Page(s): 17957 - 17964
  07/28/2020 Authors: Ellebedy AH; Nachbagauer R; Jackson KJL; Dai Y-N; Han J; Alsoussi WB; Davis CW; Stadlbauer D; Rouphael N; Chromikova V
• Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients.
  Cell Rep Med Volume: 1 Page(s): 100040
  06/23/2020 Authors: Suthar MS; Zimmerman MG; Kauffman RC; Mantus G; Linderman SL; Hudson WH; Vanderheiden A; Nyhoff L; Davis CW; Adekunle O
• 3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope-specific plasma cells and humoral immunity in nonhuman primates.
  Sci Immunol Volume: 5
  06/19/2020 Authors: Kasturi SP; Rasheed MAU; Havenar-Daughton C; Pham M; Legere T; Sher ZJ; Kovalenkov Y; Gumber S; Huang JY; Gottardo R
• Persistence of Varicella-Zoster Virus-Specific Plasma Cells in Adult Human Bone Marrow following Childhood Vaccination.
  J Virol Volume: 94
  06/16/2020 Authors: Eberhardt CS; Wieland A; Nasti TH; Grifoni A; Wilson E; Schmid DS; Pulendran B; Sette A; Waller EK; Rouphael N
• Interim results of prospective pilot phase II trial of concurrent anti-PD-1 and stereotactic radiosurgery (SRS) for melanoma and NSCLC patients with brain metastases (NCT02858869).
  Volume: 38
  05/20/2020 Authors: Khan MK; Nasti T; Yushak ML; Lawson DH; Switchenko JM; Wallington D; Kleber T; Kirmani K; Owonikoko TK; Ramalingam SS
• Rapid generation of neutralizing antibody responses in COVID-19 patients.
  medRxiv
  05/08/2020 Authors: Suthar MS; Zimmerman M; Kauffman R; Mantus G; Linderman S; Vanderheiden A; Nyhoff L; Davis C; Adekunle S; Affer M
• PD-1 blockade later but not at post-transplant attenuates chronic graft-versus-host diseases
  Volume: 204
  05/01/2020 Authors: Rhee S; Aguilar EG; Paz K; Flynn R; Kuchroo J; Sage P; Sharpe AH; Freeman GJ; Ahmed R; Blazar BR
• Dissecting human, ferret, and murine antibody and B cell responses to generate a broadly protective synthetic influenza virus hemagglutinin
  Volume: 204
  05/01/2020 Authors: Kim H; DeBeauchamp J; Stigger E; Ellebedy A; Rubrum A; El-Shesheny R; Crumpton J; Kackos C; Thomas PG; Caniza M
• Mechanism of T cell mediated hemorrhagic disease during LCMV infection
  Volume: 204
  05/01/2020 Authors: Luna E; McAfee M; Carmen J; Canter H; Ahmed R; Greenberg PD; Blattman JN
• PD-1+ stemlike CD8 T cells are resident in lymphoid tissues during persistent LCMV infection.
  Proc Natl Acad Sci U S A Volume: 117 Page(s): 4292 - 4299
  02/25/2020 Authors: Im SJ; Konieczny BT; Hudson WH; Masopust D; Ahmed R
• Minimal immune response to booster vaccination against Yellow Fever associated with pre-existing antibodies.
  Vaccine Volume: 38 Page(s): 2172 - 2182
  02/24/2020 Authors: Bovay A; Nassiri S; Maby-El Hajjami H; Marcos Mondjar P; Akondy RS; Ahmed R; Lawson B; Speiser DE; Fuertes Marraco SA
• Immune checkpoint modulation enhances HIV-1 antibody induction.
  Nat Commun Volume: 11 Page(s): 948
  02/19/2020 Authors: Bradley T; Kuraoka M; Yeh C-H; Tian M; Chen H; Cain DW; Chen X; Cheng C; Ellebedy AH; Parks R
• Harnessing Activin A Adjuvanticity to Promote Antibody Responses to BG505 HIV Envelope Trimers.
  Front Immunol Volume: 11 Page(s): 1213
  01/01/2020 Authors: Carnathan DG; Kaushik K; Ellebedy AH; Enemuo CA; Gebru EH; Dhadvai P; Rasheed MAU; Pauthner MG; Ozorowski G; Ahmed R
• Editorial: HIV and Cancer Immunotherapy: Similar Challenges and Converging Approaches.
  Front Immunol Volume: 11 Page(s): 519
  01/01/2020 Authors: Paiardini M; Dhodapkar K; Harper J; Deeks SG; Ahmed R
• Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection.
  Immunity Volume: 51 Page(s): 1043 - 1058.e4
  12/17/2019 Authors: Hudson WH; Gensheimer J; Hashimoto M; Wieland A; Valanparambil RM; Li P; Lin J-X; Konieczny BT; Im SJ; Freeman GJ
• Regulation of T and B cell responses to chronic antigenic stimulation during Infection, autoimmunity and transplantation.
  Immunol Rev Volume: 292 Page(s): 5 - 8
  11/01/2019 Authors: Ahmed R; Ford ML; Sanz I
• The Presence of Secondary Follicles in Early Stage Lung Adenocarcinoma Reflects Disease Burden
  Volume: 14 Page(s): S1146 - S1146
  11/01/2019 Authors: Obeng R; Behera M; Owonikoko T; Pillai R; Ahmed R; Ramalingam S; Sica G
• The Magnitude of IFN- Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1.
  Mol Cell Volume: 75 Page(s): 1229 - 1242.e5
  09/19/2019 Authors: Petermann F; Pkowska A; Johnson CA; Jankovic D; Shih H-Y; Jiang K; Hudson WH; Brooks SR; Sun H-W; Villarino AV
• Decreased humoral immunity to mumps in young adults immunized with MMR vaccine in childhood.
  Proc Natl Acad Sci U S A Volume: 116 Page(s): 19071 - 19076
  09/17/2019 Authors: Rasheed MAU; Hickman CJ; McGrew M; Sowers SB; Mercader S; Hopkins A; Grimes V; Yu T; Wrammert J; Mulligan MJ
• Interleukin-6/STAT3 Signaling is Prominent and Associated with Reduced Overall Survival in p16 Negative Oropharyngeal Squamous Cell Carcinoma.
  Head Neck Pathol Volume: 13 Page(s): 304 - 312
  09/01/2019 Authors: Lesinski GB; Nannapaneni S; Griffith CC; Patel M; Chen W; Chen Z; Ahmed R; Wieland A; Shin DM; Chen ZG
• The Effect of Dexamethasone on the Apd-1/L1 and Radiotherapy Stimulated Anti-Tumor Response
  Volume: 105 Page(s): S122 - S123
  09/01/2019 Authors: Buchwald ZS; Nasti T; Wieland A; Hudson W; Valanparambil R; Eberhardt C; Lawson D; Lin JY; Curran WJ; Ahmed R
• Understanding the immunology of the Zostavax shingles vaccine.
  Curr Opin Immunol Volume: 59 Page(s): 25 - 30
  08/01/2019 Authors: Sullivan NL; Eberhardt CS; Wieland A; Vora KA; Pulendran B; Ahmed R
• Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade.
  Proc Natl Acad Sci U S A Volume: 116 Page(s): 14113 - 14118
  07/09/2019 Authors: Jadhav RR; Im SJ; Hu B; Hashimoto M; Li P; Lin J-X; Leonard WJ; Greenleaf WJ; Ahmed R; Goronzy JJ
• Characterization of Virus-specific Immune Response During Varicella Zoster Virus Encephalitis in a Young Adult.
  Clin Infect Dis Volume: 69 Page(s): 348 - 351
  07/02/2019 Authors: Sullivan NL; Eberhardt CS; Wieland A; Akondy RS; Yi J; McElroy AK; Ahmed R
• Tumor-draining lymph node irradiation reduces tumor-infiltrating stem-like CD8(+)T-cells and abrogates the abscopal effect
  Volume: 79
  07/01/2019 Authors: Buchwald ZS; Nasti TH; Eberhardt CS; Wieland A; Lawson D; Curran W; Ahmed R; Khan MK
• Analysis of dengue specific memory B cells, neutralizing antibodies and binding antibodies in healthy adults from India.
  Int J Infect Dis Volume: 84S Page(s): S57 - S63
  07/01/2019 Authors: Gunisetty S; Nayak K; Chandra Rai R; Chawla Y; Reddy ES; Aggarwal C; Maheshwari D; Panda H; Ansari NA; Singh P
• Dependence of CD8 T Cell Response upon Antigen Load During Primary Infection : Analysis of Data from Yellow Fever Vaccination.
  Bull Math Biol Volume: 81 Page(s): 2553 - 2568
  07/01/2019 Authors: Moore JR; Ahmed H; McGuire D; Akondy R; Ahmed R; Antia R
• Longitudinal Analysis of the Human B Cell Response to Ebola Virus Infection.
  Cell Volume: 177 Page(s): 1566 - 1582.e17
  05/30/2019 Authors: Davis CW; Jackson KJL; McElroy AK; Halfmann P; Huang J; Chennareddy C; Piper AE; Leung Y; Albario CG; Crozier I
• Broad Hemagglutinin-Specific Memory B Cell Expansion by Seasonal Influenza Virus Infection Reflects Early-Life Imprinting and Adaptation to the Infecting Virus.
  J Virol Volume: 93
  04/15/2019 Authors: Tesini BL; Kanagaiah P; Wang J; Hahn M; Halliley JL; Chaves FA; Nguyen PQT; Nogales A; DeDiego ML; Anderson CS
• Antigenic Drift of the Influenza A(H1N1)pdm09 Virus Neuraminidase Results in Reduced Effectiveness of A/California/7/2009 (H1N1pdm09)-Specific Antibodies.
  mBio Volume: 10
  04/09/2019 Authors: Gao J; Couzens L; Burke DF; Wan H; Wilson P; Memoli MJ; Xu X; Harvey R; Wrammert J; Ahmed R
• Influenza Vaccination Documentation Rates During the First Year After Diagnosis of Diffuse Large B Cell Lymphoma.
  Clin Lymphoma Myeloma Leuk Volume: 19 Page(s): 239 - 243
  04/01/2019 Authors: Chang A; Payne JB; Allen PB; Koff JL; Ahmed R; Flowers CR; Bednarczyk RA
• Kinetics of antibody response to influenza vaccination in renal transplant recipients.
  Transpl Immunol Volume: 53 Page(s): 51 - 60
  04/01/2019 Authors: Gangappa S; Wrammert J; Wang D; Li Z-N; Liepkalns JS; Cao W; Chen J; Levine MZ; Stevens J; Sambhara S
• Influenza Virus Vaccination Elicits Poorly Adapted B Cell Responses in Elderly Individuals.
  Cell Host Microbe Volume: 25 Page(s): 357 - 366.e6
  03/13/2019 Authors: Henry C; Zheng N-Y; Huang M; Cabanov A; Rojas KT; Kaur K; Andrews SF; Palm A-KE; Chen Y-Q; Li Y
• Systematic identification of markers and drug targets on exhausted CD8+T-cells
  Volume: 7
  02/01/2019 Authors: Hudson WH; Gensheimer JL; Kissick HT; Ahmed R
• Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells.
  Nat Commun Volume: 10 Page(s): 196
  01/14/2019 Authors: Hudson WH; Prokhnevska N; Gensheimer J; Akondy R; McGuire DJ; Ahmed R; Kissick HT
• Cytokine-Mediated Regulation of CD8 T-Cell Responses During Acute and Chronic Viral Infection.
  Cold Spring Harb Perspect Biol Volume: 11
  01/02/2019 Authors: Hashimoto M; Im SJ; Araki K; Ahmed R
• Fc Receptors in Antimicrobial Protection.
  Curr Top Microbiol Immunol Volume: 423 Page(s): 119 - 150
  01/01/2019 Authors: Wieland A; Ahmed R
• Repurposing Food and Drug Administration-Approved Drugs to Promote Antitumor Immunity.
  Cancer J Volume: 25 Page(s): 88 - 99
  01/01/2019 Authors: Sukhatme VV; Ramalingam SS; Ahmed R; Sukhatme VP
• Targeting Sec23b in COPII Vesicles Regulates T Cell Immunity
  Volume: 132
  11/29/2018 Authors: Kim S; Khoriaty R; Valanparambil R; Wu J; Taylor A; Fujiwara H; Peltier D; Sun Y; Henig I; Zajac C
• Activation of miR-21-Regulated Pathways in Immune Aging Selects against Signatures Characteristic of Memory T Cells.
  Cell Rep Volume: 25 Page(s): 2148 - 2162.e5
  11/20/2018 Authors: Kim C; Hu B; Jadhav RR; Jin J; Zhang H; Cavanagh MM; Akondy RS; Ahmed R; Weyand CM; Goronzy JJ
• InVivo Delivery of Synthetic Human DNA-Encoded Monoclonal Antibodies Protect against Ebolavirus Infection in a Mouse Model.
  Cell Rep Volume: 25 Page(s): 1982 - 1993.e4
  11/13/2018 Authors: Patel A; Park DH; Davis CW; Smith TRF; Leung A; Tierney K; Bryan A; Davidson E; Yu X; Racine T
• T cell receptor sequencing of activated CD8 T cells in the blood identifies tumor-infiltrating clones that expand after PD-1 therapy and radiation in a melanoma patient.
  Cancer Immunol Immunother Volume: 67 Page(s): 1767 - 1776
  11/01/2018 Authors: Wieland A; Kamphorst AO; Adsay NV; Masor JJ; Sarmiento J; Nasti TH; Darko S; Douek DC; Xue Y; Curran WJ
• Enhancing FcR-mediated antibody effector function during persistent viral infection.
  Sci Immunol Volume: 3
  09/21/2018 Authors: Wieland A; Kamphorst AO; Valanparambil RM; Han J-H; Xu X; Choudhury BP; Ahmed R
• Combination anti-PD-1 and antiretroviral therapy provides therapeutic benefit against SIV.
  JCI Insight Volume: 3
  09/20/2018 Authors: Mylvaganam GH; Chea LS; Tharp GK; Hicks S; Velu V; Iyer SS; Deleage C; Estes JD; Bosinger SE; Freeman GJ
• Myocarditis With Radiotherapy and Immunotherapy in Multiple Myeloma.
  J Oncol Pract Volume: 14 Page(s): 561 - 564
  09/01/2018 Authors: Chang A; Nasti TH; Khan MK; Parashar S; Kaufman JL; Boise LH; Lonial S; Ahmed R; Nooka AK
• Broadly Reactive Human Monoclonal Antibodies Elicited following Pandemic H1N1 Influenza Virus Exposure Protect Mice against Highly Pathogenic H5N1 Challenge.
  J Virol Volume: 92
  08/15/2018 Authors: Nachbagauer R; Shore D; Yang H; Johnson SK; Gabbard JD; Tompkins SM; Wrammert J; Wilson PC; Stevens J; Ahmed R
• Systematic Analysis of Monoclonal Antibodies against Ebola Virus GP Defines Features that Contribute to Protection.
  Cell Volume: 174 Page(s): 938 - 952.e13
  08/09/2018 Authors: Saphire EO; Schendel SL; Fusco ML; Gangavarapu K; Gunn BM; Wec AZ; Halfmann PJ; Brannan JM; Herbert AS; Qiu X
• Breadth and Functionality of Varicella-Zoster Virus Glycoprotein-Specific Antibodies Identified after Zostavax Vaccination in Humans.
  J Virol Volume: 92
  07/15/2018 Authors: Sullivan NL; Reuter-Monslow MA; Sei J; Durr E; Davis CW; Chang C; McCausland M; Wieland A; Krah D; Rouphael N
• Lymphoid tissue fibrosis is associated with impaired vaccine responses.
  J Clin Invest Volume: 128 Page(s): 2763 - 2773
  07/02/2018 Authors: Kityo C; Makamdop KN; Rothenberger M; Chipman JG; Hoskuldsson T; Beilman GJ; Grzywacz B; Mugyenyi P; Ssali F; Akondy RS
• Determinants of antibody persistence across doses and continents after single-dose rVSV-ZEBOV vaccination for Ebola virus disease: an observational cohort study.
  Lancet Infect Dis Volume: 18 Page(s): 738 - 748
  07/01/2018 Authors: Huttner A; Agnandji ST; Combescure C; Fernandes JF; Bache EB; Kabwende L; Ndungu FM; Brosnahan J; Monath TP; Lematre B
• Identification of radiation induced exosomes as a potential in situ vaccine for melanoma growth delay.
  Volume: 36
  05/20/2018 Authors: Khan MK; Jella KK; Nasti T; Li Z; Lawson DH; Ahmed R; Dynan W
• Anti-PD1 (muDX 400) therapy given after radiation has greatest impact on (CD8+Tim3-CD73+) stem cell like cells: Implications for improved clinical trial design incorporating radiation and anti-PD1
  Volume: 36
  05/20/2018 Authors: Nasti T; Im S; Kissick H; Daugherty C; Lawson DH; Ahmed R; Khan MK
• Safety and efficacy of combining pembrolizmumab and dose escalation/fraction de-escalation SRS for melanoma and NSCLC brain metastasis: Preliminary results from arm a of a prospective pilot trial.
  Volume: 36
  05/20/2018 Authors: Khan MK; Nasti T; Masoumy L; Kamphorst AO; Yushak MI; Owonikoko TK; Kudchadkar RR; Ramalingam SS; Lawson DH; Ahmed R
• Rapid Protection against Zaire Ebolavirus (EBOV) Infection in Mice by Fully Human DNA Expression Cassette-Delivered Monoclonal Antibodies (DMAbs) Engineered from Clones Isolated from Ebola Virus Disease Survivors
  Volume: 26 Page(s): 241 - 241
  05/01/2018 Authors: Patel A; Park DH; Davis CW; Leung A; Tierney K; Reed C; Smith TRF; Gorman M; Wise MC; Yan J
• Role of PD-1 during effector CD8 T cell differentiation.
  Proc Natl Acad Sci U S A Volume: 115 Page(s): 4749 - 4754
  05/01/2018 Authors: Ahn E; Araki K; Hashimoto M; Li W; Riley JL; Cheung J; Sharpe AH; Freeman GJ; Irving BA; Ahmed R
• A High Throughput Whole Blood Assay for Analysis of Multiple Antigen-Specific T Cell Responses in Human Mycobacterium tuberculosis Infection.
  J Immunol Volume: 200 Page(s): 3008 - 3019
  04/15/2018 Authors: Whatney WE; Gandhi NR; Lindestam Arlehamn CS; Nizam A; Wu H; Quezada MJ; Campbell A; Allana S; Kabongo MM; Khayumbi J
• Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies.
  Cell Volume: 173 Page(s): 417 - 429.e10
  04/05/2018 Authors: Chen Y-Q; Wohlbold TJ; Zheng N-Y; Huang M; Huang Y; Neu KE; Lee J; Wan H; Rojas KT; Kirkpatrick E
• A Direct Comparison of in Vitro and in Vivo Nucleic Acid Delivery Mediated by Hundreds of Nanoparticles Reveals a Weak Correlation.
  Nano Lett Volume: 18 Page(s): 2148 - 2157
  03/14/2018 Authors: Paunovska K; Sago CD; Monaco CM; Hudson WH; Castro MG; Rudoltz TG; Kalathoor S; Vanover DA; Santangelo PJ; Ahmed R
• CD8 T Cell Exhaustion in Chronic Infection and Cancer: Opportunities for Interventions.
  Annu Rev Med Volume: 69 Page(s): 301 - 318
  01/29/2018 Authors: Hashimoto M; Kamphorst AO; Im SJ; Kissick HT; Pillai RN; Ramalingam SS; Araki K; Ahmed R
• Comparison of the toxicity profile of PD-1 versus PD-L1 inhibitors in non-small cell lung cancer: A systematic analysis of the literature.
  Cancer Volume: 124 Page(s): 271 - 277
  01/15/2018 Authors: Pillai RN; Behera M; Owonikoko TK; Kamphorst AO; Pakkala S; Belani CP; Khuri FR; Ahmed R; Ramalingam SS
• What Controls the Acute Viral Infection Following Yellow Fever Vaccination?
  Bull Math Biol Volume: 80 Page(s): 46 - 63
  01/01/2018 Authors: Moore J; Ahmed H; Jia J; Akondy R; Ahmed R; Antia R
• A tetravalent virus-like particle vaccine designed to display domain III of dengue envelope proteins induces multi-serotype neutralizing antibodies in mice and macaques which confer protection against antibody dependent enhancement in AG129 mice.
  PLoS Negl Trop Dis Volume: 12 Page(s): e0006191
  01/01/2018 Authors: Ramasamy V; Arora U; Shukla R; Poddar A; Shanmugam RK; White LJ; Mattocks MM; Raut R; Perween A; Tyagi P
• Effector CD8 T cells dedifferentiate into long-lived memory cells.
  Nature Volume: 552 Page(s): 404 - 409
  12/21/2017 Authors: Youngblood B; Hale JS; Kissick HT; Ahn E; Xu X; Wieland A; Araki K; West EE; Ghoneim HE; Fan Y
• Origin and differentiation of human memory CD8 T cells after vaccination.
  Nature Volume: 552 Page(s): 362 - 367
  12/21/2017 Authors: Akondy RS; Fitch M; Edupuganti S; Yang S; Kissick HT; Li KW; Youngblood BA; Abdelsamed HA; McGuire DJ; Cohen KW
• Humoral Immune Responses Against Zika Virus Infection and the Importance of Preexisting Flavivirus Immunity.
  J Infect Dis Volume: 216 Page(s): S906 - S911
  12/16/2017 Authors: Priyamvada L; Suthar MS; Ahmed R; Wrammert J
• Strategies for efficient Fc gamma R-mediated antibody effector functions during persistent viral infection
  Volume: 47 Page(s): 105 - 105
  12/01/2017 Authors: Wieland A; Kamphorst A; Han JH; Xu X; Choudhury B; Ahmed R
• Advancing dengue vaccine development.
  Science Volume: 358 Page(s): 865 - 866
  11/17/2017 Authors: Feinberg MB; Ahmed R
• A CLOSER LOOK AT ADE AND OAS IN THE SECONDARY DENGUE PLASMABLAST RESPONSE
  Volume: 95 Page(s): 230 - 230
  11/01/2017 Authors: Priyamvada L; Cho A; Onlamoon NO; Chokephaibulkit K; Pattanapanyasat K; Ahmed R; Wilson P; Wrammert J
• Translation is actively regulated during the differentiation of CD8+ effector T cells.
  Nat Immunol Volume: 18 Page(s): 1046 - 1057
  09/01/2017 Authors: Araki K; Morita M; Bederman AG; Konieczny BT; Kissick HT; Sonenberg N; Ahmed R
• Direct probing of germinal center responses reveals immunological correlates for nAb responses to an engineered HIV trimer
  Volume: 46 Page(s): 174 - 174
  08/01/2017 Authors: Havenar-Daughton C; Carnathan D; de la Pena AT; Pauthner M; Briney B; Reiss S; Wood J; Kaushik K; Rosales S; Locci M
• In Vivo Imaging of Influenza Virus Infection in Immunized Mice.
  mBio Volume: 8
  05/30/2017 Authors: Czak R; Vogel L; Lamirande EW; Bock KW; Moore IN; Ellebedy AH; Ahmed R; Mehle A; Subbarao K
• Early proliferation of PD-1+CD8 T cells in peripheral blood as predictive of response to PD-1 inhibition for patients with advanced NSCLC
  Volume: 35
  05/20/2017 Authors: Pillai RN; Kamphorst A; Yang S; Owonikoko TK; Sica G; Nasti T; Akondy R; Wieland A; Wu H; Patel N
• Metabolic Phenotypes of Response to Vaccination in Humans.
  Cell Volume: 169 Page(s): 862 - 877.e17
  05/18/2017 Authors: Li S; Sullivan NL; Rouphael N; Yu T; Banton S; Maddur MS; McCausland M; Chiu C; Canniff J; Dubey S
• Humoral cross-reactivity between Zika and dengue viruses: implications for protection and pathology.
  Emerg Microbes Infect Volume: 6 Page(s): e33
  05/10/2017 Authors: Priyamvada L; Hudson W; Ahmed R; Wrammert J
• Proliferation of PD-1+ CD8 T cells in peripheral blood after PD-1-targeted therapy in lung cancer patients.
  Proc Natl Acad Sci U S A Volume: 114 Page(s): 4993 - 4998
  05/09/2017 Authors: Kamphorst AO; Pillai RN; Yang S; Nasti TH; Akondy RS; Wieland A; Sica GL; Yu K; Koenig L; Patel NT
• Characterization of varicella zoster virus-specific monoclonal antibodies
  Volume: 198
  05/01/2017 Authors: Sullivan NL; Monslow M; Sei J; Durr E; Chang C; Mccausland M; Rouphael N; Pulendran B; Ahmed R; Vora KA
• DNA-Monoclonal Antibody (DMAb) Gene Delivery Against Ebola Virus Disease (EVD), an In Vivo DNA Vectored Approach for Achieving Sustained, Transient Serum Levels of Protective IgG
  Volume: 25 Page(s): 181 - 182
  05/01/2017 Authors: Patel A; Davis C; Park DH; Smith TRF; Leung A; Tierney K; Racine T; Gorman M; Guibinga G; Wise MC
• Correction for Mylvaganam et al., Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection.
  Proc Natl Acad Sci U S A Volume: 114 Page(s): E3366
  04/18/2017
• Simply put: Vaccination saves lives.
  Proc Natl Acad Sci U S A Volume: 114 Page(s): 4031 - 4033
  04/18/2017 Authors: Orenstein WA; Ahmed R
• Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent.
  Volume: 355 Page(s): 1423 - 1427
  03/31/2017 Authors: Kamphorst AO; Wieland A; Nasti T; Yang S; Zhang R; Barber DL; Konieczny BT; Daugherty CZ; Koenig L; Yu K
• Viral Infection Prevents Hemolytic Transfusion Reactions Following Incompatible Red Blood Cell Transfusion
  Volume: 147 Page(s): S168 - +
  03/01/2017 Authors: Sullivan H; Arthur C; Wieland A; Ahmed R; Stowell S
• Adenovirus Serotype 5 Vaccination Results in Suboptimal CD4 T Helper 1 Responses in Mice.
  J Virol Volume: 91
  03/01/2017 Authors: Lee J; Hashimoto M; Im SJ; Araki K; Jin H-T; Davis CW; Konieczny BT; Spies GA; McElrath MJ; Ahmed R
• Viral Infection Prevents Hemolytic Transfusion Reactions Following Incompatible Red Blood Cell Transfusion.
  Am J Clin Pathol Volume: 147 Page(s): S171
  03/01/2017 Authors: Sullivan H; Arthur C; Wieland A; Ahmed R; Stowell S
• Systems analysis of protective immune responses to RTS,S malaria vaccination in humans.
  Proc Natl Acad Sci U S A Volume: 114 Page(s): 2425 - 2430
  02/28/2017 Authors: Kazmin D; Nakaya HI; Lee EK; Johnson MJ; van der Most R; van den Berg RA; Ballou WR; Jongert E; Wille-Reece U; Ockenhouse C
• Dynamics of SIV-specific CXCR5+ CD8 T cells during chronic SIV infection.
  Proc Natl Acad Sci U S A Volume: 114 Page(s): 1976 - 1981
  02/21/2017 Authors: Mylvaganam GH; Rios D; Abdelaal HM; Iyer S; Tharp G; Mavigner M; Hicks S; Chahroudi A; Ahmed R; Bosinger SE
• mTOR Promotes Antiviral Humoral Immunity by Differentially Regulating CD4 Helper T Cell and B Cell Responses.
  J Virol Volume: 91
  02/15/2017 Authors: Ye L; Lee J; Xu L; Mohammed A-U-R; Li W; Hale JS; Tan WG; Wu T; Davis CW; Ahmed R
• IgG antibodies to dengue enhanced for FcRIIIA binding determine disease severity.
  Science Volume: 355 Page(s): 395 - 398
  01/27/2017 Authors: Wang TT; Sewatanon J; Memoli MJ; Wrammert J; Bournazos S; Bhaumik SK; Pinsky BA; Chokephaibulkit K; Onlamoon N; Pattanapanyasat K
• Cardiac allograft rejection as a complication of PD-1 checkpoint blockade for cancer immunotherapy: a case report.
  Cancer Immunol Immunother Volume: 66 Page(s): 45 - 50
  01/01/2017 Authors: Owonikoko TK; Kumar M; Yang S; Kamphorst AO; Pillai RN; Akondy R; Nautiyal V; Chatwal MS; Book WM; Sahu A
• Evaluation of Toxicity Profile of PD-1 versus PD-L1 Inhibitors in Non-Small Cell Lung Cancer (NSCLC)
  Volume: 12 Page(s): S253 - S254
  01/01/2017 Authors: Pillai R; Behera M; Owonikoko T; Kamphorst A; Pakkala S; Belani C; Khuri F; Ahmed R; Ramalingam S
• Characterization of Human CD8 T Cell Responses in Dengue Virus-Infected Patients from India.
  J Virol Volume: 90 Page(s): 11259 - 11278
  12/15/2016 Authors: Chandele A; Sewatanon J; Gunisetty S; Singla M; Onlamoon N; Akondy RS; Kissick HT; Nayak K; Reddy ES; Kalam H
• Direct Probing of Germinal Center Responses Reveals Immunological Features and Bottlenecks for Neutralizing Antibody Responses to HIV Env Trimer.
  Cell Rep Volume: 17 Page(s): 2195 - 2209
  11/22/2016 Authors: Havenar-Daughton C; Carnathan DG; Torrents de la Pea A; Pauthner M; Briney B; Reiss SM; Wood JS; Kaushik K; van Gils MJ; Rosales SL
• Long non-coding RNA expression during CD8(+) T cell differentiation and exhaustion
  Volume: 4
  11/01/2016 Authors: Hudson W; Kissick H; Hashimoto M; Ahmed R
• Demethylation of the PD-1 Promoter Is Imprinted during the Effector Phase of CD8 T Cell Exhaustion.
  J Virol Volume: 90 Page(s): 8934 - 8946
  10/01/2016 Authors: Ahn E; Youngblood B; Lee J; Lee J; Sarkar S; Ahmed R
• Remembrance of Professor Steven Wechsler (1948-2016).
  J Neurovirol Volume: 22 Page(s): 553 - 554
  10/01/2016 Authors: Ahmed R; Fraser NW; Ghiasi H; Jones C
• Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination.
  Nat Immunol Volume: 17 Page(s): 1226 - 1234
  10/01/2016 Authors: Ellebedy AH; Jackson KJL; Kissick HT; Nakaya HI; Davis CW; Roskin KM; McElroy AK; Oshansky CM; Elbein R; Thomas S
• Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.
  Nature Volume: 537 Page(s): 417 - 421
  09/15/2016 Authors: Im SJ; Hashimoto M; Gerner MY; Lee J; Kissick HT; Burger MC; Shan Q; Hale JS; Lee J; Nasti TH
• Kinetic Analysis of Biomarkers in a Cohort of US Patients With Ebola Virus Disease.
  Clin Infect Dis Volume: 63 Page(s): 460 - 467
  08/15/2016 Authors: McElroy AK; Harmon JR; Flietstra TD; Campbell S; Mehta AK; Kraft CS; Lyon MG; Varkey JB; Ribner BS; Kratochvil CJ
• Natural H3N2 influenza A infection in humans expands memory B cells specific for the hemagglutinin stalk domain
  Volume: 46 Page(s): 96 - 96
  08/01/2016 Authors: Tesini B; Halliley J; Ellebedy A; Kanagaiah P; Anderson C; Dediego M; Chaves F; Wang J; Krammer F; Yang H
• T cell exhaustion is reinforced by progressive de novo DNA methylation programming
  Volume: 46 Page(s): 78 - 78
  08/01/2016 Authors: Youngblood B; Ghoniem H; Abdelsamed H; Carter R; Hale S; Ahn E; Im S; Ahmed R
• Defining antigen specific plasmablast and memory B cell subsets in blood following viral infection and vaccination of humans
  Volume: 46 Page(s): 300 - 300
  08/01/2016 Authors: Ellebedy A; Jackson K; Boyd S; Ahmed R
• PD-1 dependent exhaustion of CD8(+) T cells drives chronic malaria
  Volume: 46 Page(s): 655 - 655
  08/01/2016 Authors: Karunarathne DS; Horne-Debets JM; Faleiro R; Liu QX; Lineburg EK; Poh MC; Grotenbreg GM; Hill GR; MacDonald KPA; Good MF
• The programmed death-1-PD-L1 axis mediates lethality of malaria
  Volume: 46 Page(s): 660 - 660
  08/01/2016 Authors: Horne-Debets J; Karunarathne D; Faleiro R; Renia L; Ahmed R; Sharpe A; Wykes M
• Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus.
  Proc Natl Acad Sci U S A Volume: 113 Page(s): 7852 - 7857
  07/12/2016 Authors: Priyamvada L; Quicke KM; Hudson WH; Onlamoon N; Sewatanon J; Edupuganti S; Pattanapanyasat K; Chokephaibulkit K; Mulligan MJ; Wilson PC
• PD-1 blockade synergizes with ART for restoring anti-viral CD8 T cell function and possibly destabilizing the viral reservoir in SIV infected macaques
  Volume: 19
  07/01/2016 Authors: Mylvaganam G; Hicks S; Lawson B; Nega M; Velu V; Ahmed R; Freeman G; Amara RR
• B Cell Responses during Secondary Dengue Virus Infection Are Dominated by Highly Cross-Reactive, Memory-Derived Plasmablasts.
  J Virol Volume: 90 Page(s): 5574 - 5585
  06/15/2016 Authors: Priyamvada L; Cho A; Onlamoon N; Zheng N-Y; Huang M; Kovalenkov Y; Chokephaibulkit K; Angkasekwinai N; Pattanapanyasat K; Ahmed R
• Multi-epitope Models Explain How Pre-existing Antibodies Affect the Generation of Broadly Protective Responses to Influenza.
  PLoS Pathog Volume: 12 Page(s): e1005692
  06/01/2016 Authors: Zarnitsyna VI; Lavine J; Ellebedy A; Ahmed R; Antia R
• Evaluation of toxicity profile of PD-1 versus PD-L1 inhibitors in non-small cell lung cancer (NSCLC).
  Volume: 34
  05/20/2016 Authors: Pillai RN; Behera M; Owonikoko TK; Kamphorst AO; Pakkala S; Belani CP; Khuri FR; Ahmed R; Ramalingam SS
• Tbet suppresses TH17 differentiation during viral infection
  Volume: 196
  05/01/2016 Authors: Hale JS; Mohammed AUR; Ahmed R
• Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza
  Volume: 196
  05/01/2016 Authors: Zarnitsyna VI; Ellebedy AH; Davis C; Jacob J; Ahmed R; Antia R
• Understanding heterogeneous CTL responses to the yellow fever vaccine using mathematical models.
  Volume: 196
  05/01/2016 Authors: Moore JR; Antia R; Akondy R; Jia J; Ahmed R
• Humoral and Cell-Mediated Immune Responses to Alternate Booster Schedules of Anthrax Vaccine Adsorbed in Humans.
  Clin Vaccine Immunol Volume: 23 Page(s): 326 - 338
  04/01/2016 Authors: Quinn CP; Sabourin CL; Schiffer JM; Niemuth NA; Semenova VA; Li H; Rudge TL; Brys AM; Mittler RS; Ibegbu CC
• CXCL13 is a plasma biomarker of germinal center activity.
  Proc Natl Acad Sci U S A Volume: 113 Page(s): 2702 - 2707
  03/08/2016 Authors: Havenar-Daughton C; Lindqvist M; Heit A; Wu JE; Reiss SM; Kendric K; Blanger S; Kasturi SP; Landais E; Akondy RS
• Saracatinib as a metastasis inhibitor in metastatic castration-resistant prostate cancer: A University of Chicago Phase 2 Consortium and DOD/PCF Prostate Cancer Clinical Trials Consortium Study.
  Prostate Volume: 76 Page(s): 286 - 293
  02/15/2016 Authors: Posadas EM; Ahmed RS; Karrison T; Szmulewitz RZ; O'Donnell PH; Wade JL; Shen J; Gururajan M; Sievert M; Stadler WM
• T cell memory and exhaustion
  CANCER IMMUNOLOGY RESEARCH Volume: 4
  01/01/2016 Authors: Ahmed R
• Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures.
  Immunity Volume: 43 Page(s): 1186 - 1198
  12/15/2015 Authors: Nakaya HI; Hagan T; Duraisingham SS; Lee EK; Kwissa M; Rouphael N; Frasca D; Gersten M; Mehta AK; Gaujoux R
• Role of PD-1/PD-L1 in Acute and Chronic Graft Versus Host Disease
  Volume: 126
  12/03/2015 Authors: Blazar BR; O'Connor RS; Milone MC; Dustin ML; Riley JL; Vincent BC; Serody JS; Flynn RP; Paz K; Du J
• Clearance of Incompatible RBC Is Compromised during Persistent Viral Infection
  Volume: 126
  12/03/2015 Authors: Arthur CM; Weiland A; Sullivan HC; Ahmed R; Stowell SR
• Immune history profoundly affects broadly protective B cell responses to influenza.
  Sci Transl Med Volume: 7 Page(s): 316ra192
  12/02/2015 Authors: Andrews SF; Huang Y; Kaur K; Popova LI; Ho IY; Pauli NT; Henry Dunand CJ; Taylor WM; Lim S; Huang M
• The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.
  Immunity Volume: 43 Page(s): 690 - 702
  10/20/2015 Authors: Ray JP; Staron MM; Shyer JA; Ho P-C; Marshall HD; Gray SM; Laidlaw BJ; Araki K; Ahmed R; Kaech SM
• Two heads better than one? Ipilimumab immunotherapy and radiation therapy for melanoma brain metastases.
  Neuro Oncol Volume: 17 Page(s): 1312 - 1321
  10/01/2015 Authors: Patel KR; Lawson DH; Kudchadkar RR; Carthon BC; Oliver DE; Okwan-Duodu D; Ahmed R; Khan MK
• HUMAN PLASMABLAST RESPONSES TO SECONDARY DENGUE INFECTION
  Volume: 93 Page(s): 51 - 52
  10/01/2015 Authors: Priyamvada L; Cho A; Onlamoon N; Chokephaibulkit K; Pattanapanyasat K; Ahmed R; Wilson PC; Wrammert J
• Cutting Edge: miR-17-92 Is Required for Both CD4 Th1 and T Follicular Helper Cell Responses during Viral Infection.
  J Immunol Volume: 195 Page(s): 2515 - 2519
  09/15/2015 Authors: Wu T; Wieland A; Lee J; Hale JS; Han J-H; Xu X; Ahmed R
• Masking of antigenic epitopes by antibodies shapes the humoral immune response to influenza.
  Philos Trans R Soc Lond B Biol Sci Volume: 370
  09/05/2015 Authors: Zarnitsyna VI; Ellebedy AH; Davis C; Jacob J; Ahmed R; Antia R
• Biomarker evaluation for PD-1 targeted therapies in non-small cell lung cancer (NSCLC) patients
  Volume: 75
  08/01/2015 Authors: Kamphorst AO; Pillai RN; Yang S; Akondy R; Koenig L; Yu K; McCausland M; Sica G; Khuri FR; Owonikoko TK
• Editorial overview: Vaccines: Vaccines for cancer and infectious diseases.
  Curr Opin Immunol Volume: 35 Page(s): v - vii
  08/01/2015 Authors: Mascola JR; Ahmed R
• Corrigendum: An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction.
  Nat Commun Volume: 6 Page(s): 7657
  07/08/2015 Authors: Zhu C; Sakuishi K; Xiao S; Sun Z; Zaghouani S; Gu G; Wang C; Tan DJ; Wu C; Rangachari M
• Anti-HA Glycoforms Drive B Cell Affinity Selection and Determine Influenza Vaccine Efficacy.
  Cell Volume: 162 Page(s): 160 - 169
  07/02/2015 Authors: Wang TT; Maamary J; Tan GS; Bournazos S; Davis CW; Krammer F; Schlesinger SJ; Palese P; Ahmed R; Ravetch JV
• Beyond adjuvants: immunomodulation strategies to enhance T cell immunity.
  Vaccine Volume: 33 Suppl 2 Page(s): B21 - B28
  06/08/2015 Authors: Kamphorst AO; Araki K; Ahmed R
• Characterization of long-lived human memory CD8 T cells specific to yellow fever virus
  Volume: 194
  05/01/2015 Authors: Yang S; Akondy R; Youngblood B; Edupuganti S; Mulligan M; Ahmed R
• Differential role of B7 co-stimulation on B cells and dendritic cells for Th1 and Tfh differentiation
  Volume: 194
  05/01/2015 Authors: Kamphorst A; Watanabe M; Araki K; Rasheed MAU; Davis C; Yang S; Konieczny B; Hodes R; Ahmed R
• Dnmt3a mediated de novo DNA methylation programming enforces T cell exhaustion
  Volume: 194
  05/01/2015 Authors: Youngblood B; Hale S; Ahn E; Im S; Ghoneim H; Abdelsamed H; Ahmed R
• NF-B regulates PD-1 expression in macrophages.
  J Immunol Volume: 194 Page(s): 4545 - 4554
  05/01/2015 Authors: Bally APR; Lu P; Tang Y; Austin JW; Scharer CD; Ahmed R; Boss JM
• LCMV-specific CD4 T cells induce immunopathology and impair immune protection following chronic LCMV infection
  Volume: 194
  05/01/2015 Authors: Penaloza-MacMaster P; Barber D; Wherry E; Provine N; Teigler JE; Parenteau L; Blackmore S; Borducchi E; Larocca R; Yates K
• Characterization of activated B cells, a novel antigen-specific B cell population that emerges in blood after infection and vaccination in humans
  Volume: 194
  05/01/2015 Authors: Ellebedy A; Ahmed R
• Human Ebola virus infection results in substantial immune activation.
  Proc Natl Acad Sci U S A Volume: 112 Page(s): 4719 - 4724
  04/14/2015 Authors: McElroy AK; Akondy RS; Davis CW; Ellebedy AH; Mehta AK; Kraft CS; Lyon GM; Ribner BS; Varkey J; Sidney J
• Initial viral load determines the magnitude of the human CD8 T cell response to yellow fever vaccination.
  Proc Natl Acad Sci U S A Volume: 112 Page(s): 3050 - 3055
  03/10/2015 Authors: Akondy RS; Johnson PLF; Nakaya HI; Edupuganti S; Mulligan MJ; Lawson B; Miller JD; Pulendran B; Antia R; Ahmed R
• Preexisting human antibodies neutralize recently emerged H7N9 influenza strains.
  J Clin Invest Volume: 125 Page(s): 1255 - 1268
  03/02/2015 Authors: Henry Dunand CJ; Leon PE; Kaur K; Tan GS; Zheng N-Y; Andrews S; Huang M; Qu X; Huang Y; Salgado-Ferrer M
• Antibody effector functions mediated by Fc-receptors are compromised during persistent viral infection.
  Immunity Volume: 42 Page(s): 367 - 378
  02/17/2015 Authors: Wieland A; Shashidharamurthy R; Kamphorst AO; Han J-H; Aubert RD; Choudhury BP; Stowell SR; Lee J; Punkosdy GA; Shlomchik MJ
• An IL-27/NFIL3 signalling axis drives Tim-3 and IL-10 expression and T-cell dysfunction.
  Nat Commun Volume: 6 Page(s): 6072
  01/23/2015 Authors: Zhu C; Sakuishi K; Xiao S; Sun Z; Zaghouani S; Gu G; Wang C; Tan DJ; Wu C; Rangachari M
• Malaria induces anemia through CD8+ T cell-dependent parasite clearance and erythrocyte removal in the spleen.
  mBio Volume: 6
  01/20/2015 Authors: Safeukui I; Gomez ND; Adelani AA; Burte F; Afolabi NK; Akondy R; Velazquez P; Holder A; Tewari R; Buffet P
• Vaccine-elicited CD4 T cells induce immunopathology after chronic LCMV infection.
  Science Volume: 347 Page(s): 278 - 282
  01/16/2015 Authors: Penaloza-MacMaster P; Barber DL; Wherry EJ; Provine NM; Teigler JE; Parenteau L; Blackmore S; Borducchi EN; Larocca RA; Yates KB
• Inducible RNAi in vivo reveals that the transcription factor BATF is required to initiate but not maintain CD8+ T-cell effector differentiation.
  Proc Natl Acad Sci U S A Volume: 112 Page(s): 512 - 517
  01/13/2015 Authors: Godec J; Cowley GS; Barnitz RA; Alkan O; Root DE; Sharpe AH; Haining WN
• Reinvigorating Exhausted T Cells by Blockade of the PD-1 Pathway.
  For Immunopathol Dis Therap Volume: 6 Page(s): 7 - 17
  01/01/2015 Authors: Lee J; Ahn E; Kissick HT; Ahmed R
• B cell responses to influenza infection and vaccination.
  Curr Top Microbiol Immunol Volume: 386 Page(s): 381 - 398
  01/01/2015 Authors: Chiu C; Ellebedy AH; Wrammert J; Ahmed R
• Memory T follicular helper CD4 T cells.
  Front Immunol Volume: 6 Page(s): 16
  01/01/2015 Authors: Hale JS; Ahmed R
• High Affinity Antibodies against Influenza Characterize the Plasmablast Response in SLE Patients After Vaccination.
  PLoS One Volume: 10 Page(s): e0125618
  01/01/2015 Authors: Kaur K; Zheng N-Y; Smith K; Huang M; Li L; Pauli NT; Henry Dunand CJ; Lee J-H; Morrissey M; Wu Y
• Memory CD8 T cell transcriptional plasticity.
  F1000Prime Rep Volume: 7 Page(s): 38
  01/01/2015 Authors: Youngblood B; Hale JS; Ahmed R
• Autophagy is essential for effector CD8(+) T cell survival and memory formation.
  Nat Immunol Volume: 15 Page(s): 1152 - 1161
  12/01/2014 Authors: Xu X; Araki K; Li S; Han J-H; Ye L; Tan WG; Konieczny BT; Bruinsma MW; Martinez J; Pearce EL
• Corrigendum: Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen.
  Nat Protoc Volume: 9 Page(s): 2903
  11/20/2014 Authors: Smith K; Garman L; Wrammert J; Zheng N-Y; Capra JD; Ahmed R; Wilson PC
• Potential antigenic explanation for atypical H1N1 infections among middle-aged adults during the 2013-2014 influenza season.
  Proc Natl Acad Sci U S A Volume: 111 Page(s): 15798 - 15803
  11/04/2014 Authors: Linderman SL; Chambers BS; Zost SJ; Parkhouse K; Li Y; Herrmann C; Ellebedy AH; Carter DM; Andrews SF; Zheng N-Y
• PD-1 BLOCKADE AS AN ADJUNCT THERAPY FOR ART: IMPROVES ANTI-SIV IMMUNITY, VIROLOGIC RESPONSE TO ART AND GUT CD4 T-CELL RESTORATION
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 393 - 393
  10/01/2014 Authors: Velu V; Mylvaganam G; Freeman G; Ahmed R; Amara R
• DETERMINING THE MAGNITUDE, QUALITY, PERSISTENCE, AND BREADTH OF HIV ENV-SPECIFIC HUMORAL IMMUNE RESPONSE IN RHESUS MACAQUES AFTER GP140 IMMUNIZATION WITH NANOPARTICLES FORMULATED TLR LIGANDS
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 43 Page(s): 414 - 415
  10/01/2014 Authors: Mohammed AUR; Kovalenkov Y; Silveira ELV; Kasturi SP; Legere TH; Jinnah ZS; Villinger F; Pulendran B; Ahmed R; Wrammert J
• Induction of broadly cross-reactive antibody responses to the influenza HA stem region following H5N1 vaccination in humans.
  Proc Natl Acad Sci U S A Volume: 111 Page(s): 13133 - 13138
  09/09/2014 Authors: Ellebedy AH; Krammer F; Li G-M; Miller MS; Chiu C; Wrammert J; Chang CY; Davis CW; McCausland M; Elbein R
• Interplay between regulatory T cells and PD-1 in modulating T cell exhaustion and viral control during chronic LCMV infection.
  J Exp Med Volume: 211 Page(s): 1905 - 1918
  08/25/2014 Authors: Penaloza-MacMaster P; Kamphorst AO; Wieland A; Araki K; Iyer SS; West EE; O'Mara L; Yang S; Konieczny BT; Sharpe AH
• Dengue virus infection induces expansion of a CD14(+)CD16(+) monocyte population that stimulates plasmablast differentiation.
  Cell Host Microbe Volume: 16 Page(s): 115 - 127
  07/09/2014 Authors: Kwissa M; Nakaya HI; Onlamoon N; Wrammert J; Villinger F; Perng GC; Yoksan S; Pattanapanyasat K; Chokephaibulkit K; Ahmed R
• Biogenesis of influenza a virus hemagglutinin cross-protective stem epitopes.
  PLoS Pathog Volume: 10 Page(s): e1004204
  06/01/2014 Authors: Magadn JG; Altman MO; Ince WL; Hickman HD; Stevens J; Chevalier A; Baker D; Wilson PC; Ahmed R; Bennink JR
• STAT3, STAT4, NFATc1, and CTCF regulate PD-1 through multiple novel regulatory regions in murine T cells.
  J Immunol Volume: 192 Page(s): 4876 - 4886
  05/15/2014 Authors: Austin JW; Lu P; Majumder P; Ahmed R; Boss JM
• Translational control of memory CD8 T cell differentiation
  JOURNAL OF IMMUNOLOGY Volume: 192
  05/01/2014 Authors: Araki K; Konieczny B; Morita M; Sonenberg N; Ahmed R
• Blimp-1 represses CD8 T cell expression of PD-1 using a feed-forward transcriptional circuit during acute viral infection.
  J Exp Med Volume: 211 Page(s): 515 - 527
  03/10/2014 Authors: Lu P; Youngblood BA; Austin JW; Mohammed AUR; Butler R; Ahmed R; Boss JM
• Programmed Cell Death 1-Directed Immunotherapy for Enhancing T-Cell Function.
  Cold Spring Harb Symp Quant Biol
  03/03/2014 Authors: Araki K; Youngblood B; Ahmed R
• Broadly reactive human CD8 T cells that recognize an epitope conserved between VZV, HSV and EBV.
  PLoS Pathog Volume: 10 Page(s): e1004008
  03/01/2014 Authors: Chiu C; McCausland M; Sidney J; Duh F-M; Rouphael N; Mehta A; Mulligan M; Carrington M; Wieland A; Sullivan NL
• Differential impact of PD-1 and/or interleukin-10 blockade on HIV-1-specific CD4 T cell and antigen-presenting cell functions.
  J Virol Volume: 88 Page(s): 2508 - 2518
  03/01/2014 Authors: Porichis F; Hart MG; Zupkosky J; Barblu L; Kwon DS; McMullen A; Brennan T; Ahmed R; Freeman GJ; Kavanagh DG
• Introduction.
  Semin Cutan Med Surg Volume: 33 Page(s): 1
  03/01/2014 Authors: Fox L; Shinkai K
• Vaccines at what price?
  Vaccine Volume: 32 Page(s): 1029 - 1030
  02/19/2014 Authors: Stephens DS; Ahmed R; Orenstein WA
• Molecular signatures of antibody responses derived from a systems biology study of five human vaccines.
  Nat Immunol Volume: 15 Page(s): 195 - 204
  02/01/2014 Authors: Li S; Rouphael N; Duraisingham S; Romero-Steiner S; Presnell S; Davis C; Schmidt DS; Johnson SE; Milton A; Rajam G
• PD-1 dependent exhaustion of CD8+ T cells drives chronic malaria.
  Cell Rep Volume: 5 Page(s): 1204 - 1213
  12/12/2013 Authors: Horne-Debets JM; Faleiro R; Karunarathne DS; Liu XQ; Lineburg KE; Poh CM; Grotenbreg GM; Hill GR; MacDonald KPA; Good MF
• Identification of novel markers for mouse CD4(+) T follicular helper cells.
  Eur J Immunol Volume: 43 Page(s): 3219 - 3232
  12/01/2013 Authors: Iyer SS; Latner DR; Zilliox MJ; McCausland M; Akondy RS; Penaloza-Macmaster P; Hale JS; Ye L; Mohammed A-U-R; Yamaguchi T
• Expression Of PD-L1 Is Required To Control Acute GvHD In Allo-HSCT Recipients
  Volume: 122
  11/15/2013 Authors: Hossain MS; El-Najjar VF; Jaye DL; Ahmed R; Waller EK
• Co-administration of Rapamycin with a DNA/MVA SIV Vaccine Improves Memory CD8 T Cell Response and Enhances Control of SIV251 Infection
  Volume: 29 Page(s): A11 - A11
  11/01/2013 Authors: Sadagopal S; Kwa S; Basu R; Gangadhara S; Araki K; Ahmed R; Amara R
• Host programmed death ligand 1 is dominant over programmed death ligand 2 expression in regulating graft-versus-host disease lethality.
  Blood Volume: 122 Page(s): 3062 - 3073
  10/24/2013 Authors: Saha A; Aoyama K; Taylor PA; Koehn BH; Veenstra RG; Panoskaltsis-Mortari A; Munn DH; Murphy WJ; Azuma M; Yagita H
• Global DNA methylation remodeling accompanies CD8 T cell effector function.
  J Immunol Volume: 191 Page(s): 3419 - 3429
  09/15/2013 Authors: Scharer CD; Barwick BG; Youngblood BA; Ahmed R; Boss JM
• Immunotherapy of chronic hepatitis C virus infection with antibodies against programmed cell death-1 (PD-1).
  Proc Natl Acad Sci U S A Volume: 110 Page(s): 15001 - 15006
  09/10/2013 Authors: Fuller MJ; Callendret B; Zhu B; Freeman GJ; Hasselschwert DL; Satterfield W; Sharpe AH; Dustin LB; Rice CM; Grakoui A
• CD4 T-cell immunotherapy for chronic viral infections and cancer.
  Immunotherapy Volume: 5 Page(s): 975 - 987
  09/01/2013 Authors: Kamphorst AO; Ahmed R
• In vitro assessment of the immunological significance of a human monoclonal antibody directed to the influenza a virus nucleoprotein.
  Clin Vaccine Immunol Volume: 20 Page(s): 1333 - 1337
  08/01/2013 Authors: Bodewes R; Geelhoed-Mieras MM; Wrammert J; Ahmed R; Wilson PC; Fouchier RAM; Osterhaus ADME; Rimmelzwaan GF
• Immune history shapes specificity of pandemic H1N1 influenza antibody responses.
  J Exp Med Volume: 210 Page(s): 1493 - 1500
  07/29/2013 Authors: Li Y; Myers JL; Bostick DL; Sullivan CB; Madara J; Linderman SL; Liu Q; Carter DM; Wrammert J; Esposito S
• Cutting edge: Prolonged exposure to HIV reinforces a poised epigenetic program for PD-1 expression in virus-specific CD8 T cells.
  J Immunol Volume: 191 Page(s): 540 - 544
  07/15/2013 Authors: Youngblood B; Noto A; Porichis F; Akondy RS; Ndhlovu ZM; Austin JW; Bordi R; Procopio FA; Miura T; Allen TM
• Strength of PD-1 signaling differentially affects T-cell effector functions.
  Proc Natl Acad Sci U S A Volume: 110 Page(s): E2480 - E2489
  07/02/2013 Authors: Wei F; Zhong S; Ma Z; Kong H; Medvec A; Ahmed R; Freeman GJ; Krogsgaard M; Riley JL
• T-cell memory differentiation: insights from transcriptional signatures and epigenetics.
  Immunology Volume: 139 Page(s): 277 - 284
  07/01/2013 Authors: Youngblood B; Hale JS; Ahmed R
• Interleukin-21 is a critical cytokine for the generation of virus-specific long-lived plasma cells.
  J Virol Volume: 87 Page(s): 7737 - 7746
  07/01/2013 Authors: Rasheed MAU; Latner DR; Aubert RD; Gourley T; Spolski R; Davis CW; Langley WA; Ha S-J; Ye L; Sarkar S
• PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells.
  J Clin Invest Volume: 123 Page(s): 2604 - 2615
  06/01/2013 Authors: West EE; Jin H-T; Rasheed A-U; Penaloza-Macmaster P; Ha S-J; Tan WG; Youngblood B; Freeman GJ; Smith KA; Ahmed R
• Manipulating the PD-1 pathway to improve immunity.
  Curr Opin Immunol Volume: 25 Page(s): 381 - 388
  06/01/2013 Authors: Kamphorst AO; Ahmed R
• Viral vaccines: past successes and future challenges.
  Curr Opin Virol Volume: 3 Page(s): 307 - 308
  06/01/2013 Authors: Ahmed R; Burton DR
• Accelerating next-generation vaccine development for global disease prevention.
  Science Volume: 340 Page(s): 1232910
  05/31/2013 Authors: Koff WC; Burton DR; Johnson PR; Walker BD; King CR; Nabel GJ; Ahmed R; Bhan MK; Plotkin SA
• Viral infection alters subnuclear localization of PD-1 and CD62L loci in LCMV-specific CD8 T-cells (P6369)
  Volume: 190
  05/01/2013 Authors: Sacristan C; Youngblood B; Xu J; Lu P; McGary K; Hewitt S; Skok J; Boss J; Ahmed R; Dustin M
• Antigen-specific T cell and B cell responses to the herpes zoster vaccine Zostavax (R) in the young and elderly
  Volume: 190
  05/01/2013 Authors: Sullivan N; McCausland M; Chiu C; Sidney J; Rouphael N; Mehta A; Mulligan M; Peters B; Sette A; Pulendran B
• Pillars Article: Cytotoxic T-cell Memory without Antigen. Nature. 1994. 369: 648-652.
  J Immunol Volume: 190 Page(s): 4445 - 4449
  05/01/2013 Authors: Lau LL; Jamieson BD; Somasundaram T; Ahmed R
• Distinct memory CD4+ T cells with commitment to T follicular helper- and T helper 1-cell lineages are generated after acute viral infection.
  Immunity Volume: 38 Page(s): 805 - 817
  04/18/2013 Authors: Hale JS; Youngblood B; Latner DR; Mohammed AUR; Ye L; Akondy RS; Wu T; Iyer SS; Ahmed R
• AMPK: a metabolic switch for CD8+ T-cell memory.
  Eur J Immunol Volume: 43 Page(s): 878 - 881
  04/01/2013 Authors: Araki K; Ahmed R
• Cross-reactive humoral responses to influenza and their implications for a universal vaccine.
  Ann N Y Acad Sci Volume: 1283 Page(s): 13 - 21
  04/01/2013 Authors: Chiu C; Wrammert J; Li G-M; McCausland M; Wilson PC; Ahmed R
• Most influenza a virions fail to express at least one essential viral protein.
  J Virol Volume: 87 Page(s): 3155 - 3162
  03/01/2013 Authors: Brooke CB; Ince WL; Wrammert J; Ahmed R; Wilson PC; Bennink JR; Yewdell JW
• Comparative analysis of simian immunodeficiency virus gag-specific effector and memory CD8+ T cells induced by different adenovirus vectors.
  J Virol Volume: 87 Page(s): 1359 - 1372
  02/01/2013 Authors: Tan WG; Jin H-T; West EE; Penaloza-MacMaster P; Wieland A; Zilliox MJ; McElrath MJ; Barouch DH; Ahmed R
• Programmed cell death 1-directed immunotherapy for enhancing T-cell function.
  Cold Spring Harb Symp Quant Biol Volume: 78 Page(s): 239 - 247
  01/01/2013 Authors: Araki K; Youngblood B; Ahmed R
• A randomized, double-blind, controlled trial of the 17D yellow fever virus vaccine given in combination with immune globulin or placebo: comparative viremia and immunogenicity.
  Am J Trop Med Hyg Volume: 88 Page(s): 172 - 177
  01/01/2013 Authors: Edupuganti S; Eidex RB; Keyserling H; Akondy RS; Lanciotti R; Orenstein W; del Rio C; Pan Y; Querec T; Lipman H
• mTOR, linking metabolism and immunity.
  Semin Immunol Volume: 24 Page(s): 429 - 435
  12/01/2012 Authors: Xu X; Ye L; Araki K; Ahmed R
• A three-dose intramuscular injection schedule of anthrax vaccine adsorbed generates sustained humoral and cellular immune responses to protective antigen and provides long-term protection against inhalation anthrax in rhesus macaques.
  Clin Vaccine Immunol Volume: 19 Page(s): 1730 - 1745
  11/01/2012 Authors: Quinn CP; Sabourin CL; Niemuth NA; Li H; Semenova VA; Rudge TL; Mayfield HJ; Schiffer J; Mittler RS; Ibegbu CC
• Progressive vaccinia: case description and laboratory-guided therapy with vaccinia immune globulin, ST-246, and CMX001.
  J Infect Dis Volume: 206 Page(s): 1372 - 1385
  11/01/2012 Authors: Lederman ER; Davidson W; Groff HL; Smith SK; Warkentien T; Li Y; Wilkins KA; Karem KL; Akondy RS; Ahmed R
• A Blueprint for HIV Vaccine Discovery.
  Cell Host Microbe Volume: 12 Page(s): 396 - 407
  10/18/2012 Authors: Burton DR; Ahmed R; Barouch DH; Butera ST; Crotty S; Godzik A; Kaufmann DE; McElrath MJ; Nussenzweig MC; Pulendran B
• Different memory T cell phenotypes are elicited by Ad5 and rare adenoviruses
  RETROVIROLOGY Volume: 9
  09/13/2012 Authors: Penaloza P; Borducchi E; McNally A; Simmons N; Teigler J; Provine N; Tan W; Ahmed R; Barouch DH
• ZBTB32 is an early repressor of the CIITA and MHC class II gene expression during B cell differentiation to plasma cells.
  J Immunol Volume: 189 Page(s): 2393 - 2403
  09/01/2012 Authors: Yoon HS; Scharer CD; Majumder P; Davis CW; Butler R; Zinzow-Kramer W; Skountzou I; Koutsonanos DG; Ahmed R; Boss JM
• How do antigenically varying pathogens avoid cross-reactive responses to invariant antigens?
  Proc Biol Sci Volume: 279 Page(s): 2777 - 2785
  07/22/2012 Authors: Johnson PLF; Kochin BF; Ahmed R; Antia R
• Born this way? Understanding the immunological basis of effective HIV control.
  Nat Immunol Volume: 13 Page(s): 632 - 634
  06/19/2012 Authors: Feinberg MB; Ahmed R
• Temporal expression of microRNA cluster miR-17-92 regulates effector and memory CD8+ T-cell differentiation.
  Proc Natl Acad Sci U S A Volume: 109 Page(s): 9965 - 9970
  06/19/2012 Authors: Wu T; Wieland A; Araki K; Davis CW; Ye L; Hale JS; Ahmed R
• Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells.
  Proc Natl Acad Sci U S A Volume: 109 Page(s): 9047 - 9052
  06/05/2012 Authors: Li G-M; Chiu C; Wrammert J; McCausland M; Andrews SF; Zheng N-Y; Lee J-H; Huang M; Qu X; Edupuganti S
• CIITA promoter I CARD-deficient mice express functional MHC class II genes in myeloid and lymphoid compartments.
  Genes Immun Volume: 13 Page(s): 299 - 310
  06/01/2012 Authors: Zinzow-Kramer WM; Long AB; Youngblood BA; Rosenthal KM; Butler R; Mohammed A-U-R; Skountzou I; Ahmed R; Evavold BD; Boss JM
• A Prospective Comparative Study of Immune Responses to Influenza Vaccination in Transplant Recipients and Healthy Volunteers
  Volume: 12 Page(s): 281 - 281
  05/01/2012 Authors: Wrammert J; Mehta AK; McCausland M; Kokko K; Ahmed R; Larsen CP
• Different memory T cell phenotypes are elicited by Ad5 and rare adenoviruses
  Volume: 188
  05/01/2012 Authors: Penaloza-MacMaster P; Borducci E; McNally A; Simmons N; Iampietro J; Provine N; Teigler J; Tan W; Ahmed R; Barouch D
• Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function.
  Immunity Volume: 36 Page(s): 586 - 599
  04/20/2012 Authors: Lin J-X; Li P; Liu D; Jin HT; He J; Ata Ur Rasheed M; Rochman Y; Wang L; Cui K; Liu C
• Rapid and massive virus-specific plasmablast responses during acute dengue virus infection in humans.
  J Virol Volume: 86 Page(s): 2911 - 2918
  03/01/2012 Authors: Wrammert J; Onlamoon N; Akondy RS; Perng GC; Polsrila K; Chandele A; Kwissa M; Pulendran B; Wilson PC; Wittawatmongkol O
• Acquired transcriptional programming in functional and exhausted virus-specific CD8 T cells.
  Curr Opin HIV AIDS Volume: 7 Page(s): 50 - 57
  01/01/2012 Authors: Youngblood B; Wherry EJ; Ahmed R
• Re-engaging cross-reactive memory B cells: the influenza puzzle.
  Front Immunol Volume: 3 Page(s): 53
  01/01/2012 Authors: Ellebedy AH; Ahmed R
• Protein energy malnutrition impairs homeostatic proliferation of memory CD8 T cells.
  J Immunol Volume: 188 Page(s): 77 - 84
  01/01/2012 Authors: Iyer SS; Chatraw JH; Tan WG; Wherry EJ; Becker TC; Ahmed R; Kapasi ZF
• Antibody pressure by a human monoclonal antibody targeting the 2009 pandemic H1N1 virus hemagglutinin drives the emergence of a virus with increased virulence in mice.
  mBio Volume: 3
  01/01/2012 Authors: O'Donnell CD; Vogel L; Wright A; Das SR; Wrammert J; Li G-M; McCausland M; Zheng N-Y; Yewdell JW; Ahmed R
• Antigen-specific CD4 T-cell help rescues exhausted CD8 T cells during chronic viral infection.
  Proc Natl Acad Sci U S A Volume: 108 Page(s): 21182 - 21187
  12/27/2011 Authors: Aubert RD; Kamphorst AO; Sarkar S; Vezys V; Ha S-J; Barber DL; Ye L; Sharpe AH; Freeman GJ; Ahmed R
• TOR in the immune system.
  Curr Opin Cell Biol Volume: 23 Page(s): 707 - 715
  12/01/2011 Authors: Araki K; Ellebedy AH; Ahmed R
• Learning vaccinology from viral infections.
  J Exp Med Volume: 208 Page(s): 2347 - 2349
  11/21/2011 Authors: Ahmed R; Pulendran B
• Human CD8 and CD4 T cell memory to lymphocytic choriomeningitis virus infection.
  J Virol Volume: 85 Page(s): 11770 - 11780
  11/01/2011 Authors: Kotturi MF; Swann JA; Peters B; Arlehamn CL; Sidney J; Kolla RV; James EA; Akondy RS; Ahmed R; Kwok WW
• Moving ahead an HIV vaccine: use both arms to beat HIV.
  Nat Med Volume: 17 Page(s): 1194 - 1195
  10/11/2011 Authors: Walker BD; Ahmed R; Plotkin S
• Chronic virus infection enforces demethylation of the locus that encodes PD-1 in antigen-specific CD8(+) T cells.
  Immunity Volume: 35 Page(s): 400 - 412
  09/23/2011 Authors: Youngblood B; Oestreich KJ; Ha S-J; Duraiswamy J; Akondy RS; West EE; Wei Z; Lu P; Austin JW; Riley JL
• HIV-DNA priming alters T cell responses to HIV-adenovirus vaccine even when responses to DNA are undetectable.
  J Immunol Volume: 187 Page(s): 3391 - 3401
  09/15/2011 Authors: De Rosa SC; Thomas EP; Bui J; Huang Y; deCamp A; Morgan C; Kalams SA; Tomaras GD; Akondy R; Ahmed R
• Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load.
  Immunity Volume: 35 Page(s): 285 - 298
  08/26/2011 Authors: West EE; Youngblood B; Tan WG; Jin H-T; Araki K; Alexe G; Konieczny BT; Calpe S; Freeman GJ; Terhorst C
• 4-1BB signaling synergizes with programmed death ligand 1 blockade to augment CD8 T cell responses during chronic viral infection.
  J Immunol Volume: 187 Page(s): 1634 - 1642
  08/15/2011 Authors: Vezys V; Penaloza-MacMaster P; Barber DL; Ha S-J; Konieczny B; Freeman GJ; Mittler RS; Ahmed R
• Systems biology of vaccination for seasonal influenza in humans.
  Nat Immunol Volume: 12 Page(s): 786 - 795
  07/10/2011 Authors: Nakaya HI; Wrammert J; Lee EK; Racioppi L; Marie-Kunze S; Haining WN; Means AR; Kasturi SP; Khan N; Li G-M
• Opposing effects of CD70 costimulation during acute and chronic lymphocytic choriomeningitis virus infection of mice.
  J Virol Volume: 85 Page(s): 6168 - 6174
  07/01/2011 Authors: Penaloza-MacMaster P; Ur Rasheed A; Iyer SS; Yagita H; Blazar BR; Ahmed R
• Vaccination alters the balance between protective immunity, exhaustion, escape, and death in chronic infections.
  J Virol Volume: 85 Page(s): 5565 - 5570
  06/01/2011 Authors: Johnson PLF; Kochin BF; McAfee MS; Stromnes IM; Regoes RR; Ahmed R; Blattman JN; Antia R
• Immunological mechanisms of vaccination.
  Nat Immunol Volume: 12 Page(s): 509 - 517
  06/01/2011 Authors: Pulendran B; Ahmed R
• Distinctive TLR7 signaling, type I IFN production, and attenuated innate and adaptive immune responses to yellow fever virus in a primate reservoir host.
  J Immunol Volume: 186 Page(s): 6406 - 6416
  06/01/2011 Authors: Mandl JN; Akondy R; Lawson B; Kozyr N; Staprans SI; Ahmed R; Feinberg MB
• The role of LAT in increased CD8+ T cell exhaustion in trigeminal ganglia of mice latently infected with herpes simplex virus 1.
  J Virol Volume: 85 Page(s): 4184 - 4197
  05/01/2011 Authors: Allen SJ; Hamrah P; Gate D; Mott KR; Mantopoulos D; Zheng L; Town T; Jones C; von Andrian UH; Freeman GJ
• Phenotype, function, and gene expression profiles of programmed death-1(hi) CD8 T cells in healthy human adults.
  J Immunol Volume: 186 Page(s): 4200 - 4212
  04/01/2011 Authors: Duraiswamy J; Ibegbu CC; Masopust D; Miller JD; Araki K; Doho GH; Tata P; Gupta S; Zilliox MJ; Nakaya HI
• Viral infection duration mediates locus specific de novo DNA methylation in antigen-specific CD8 T cells
  JOURNAL OF IMMUNOLOGY Volume: 186
  04/01/2011 Authors: Youngblood B; Oestreich K; Ha S-J; Duraiswamy J; Akondy R; Wei Z; Austin J; Riley J; Boss J; Ahmed R
• Immunologic Ramifications of Depletion Induction Therapy and CMV Viremia in a Renal Transplant Cohort.
  Volume: 11 Page(s): 389 - 389
  04/01/2011 Authors: Mehta AK; McCausland M; Joseph J; Cheeseman J; Duraiswamy J; Mulupuri P; Gourley T; Miller J; Kokko K; Kirk AD
• Chronic Kidney Disease and CMV Drive Patient Specific Pre-Transplant Immune Deviations Toward Terminal Differentiation and Exhaustion.
  Volume: 11 Page(s): 388 - 388
  04/01/2011 Authors: Mehta AK; McCausland M; Lo DJ; Joseph J; Cheeseman J; Elbein R; Gourley T; Mulupuri P; Miller J; Kirk AD
• Coordinated regulation of PD-1 gene expression and nuclear localization during virus-specific memory CD8+T cell differentiation
  JOURNAL OF IMMUNOLOGY Volume: 186
  04/01/2011 Authors: Sacristan C; Youngblood B; Xu J; Shipper K; Skok J; Boss J; Ahmed R; Dustin M
• FoxP3+CD4+cells promote CD8 T cell exhaustion during chronic infection
  JOURNAL OF IMMUNOLOGY Volume: 186
  04/01/2011 Authors: Penaloza-MacMaster P; Araki K; Kamphorst A; Iyer S; West E; Konieczny B; Freeman G; Rudenski A; Ahmed R
• Regulatory T-cell expansion during chronic viral infection is dependent on endogenous retroviral superantigens.
  Proc Natl Acad Sci U S A Volume: 108 Page(s): 3677 - 3682
  03/01/2011 Authors: Punkosdy GA; Blain M; Glass DD; Lozano MM; O'Mara L; Dudley JP; Ahmed R; Shevach EM
• Insights into human CD8(+) T-cell memory using the yellow fever and smallpox vaccines.
  Immunol Cell Biol Volume: 89 Page(s): 340 - 345
  03/01/2011 Authors: Ahmed R; Akondy RS
• Sirolimus enhances the magnitude and quality of viral-specific CD8+ T-cell responses to vaccinia virus vaccination in rhesus macaques.
  Am J Transplant Volume: 11 Page(s): 613 - 618
  03/01/2011 Authors: Turner AP; Shaffer VO; Araki K; Martens C; Turner PL; Gangappa S; Ford ML; Ahmed R; Kirk AD; Larsen CP
• Phenotypic and functional profiling of malaria-induced CD8 and CD4 T cells during blood-stage infection with Plasmodium yoelii.
  Immunology Volume: 132 Page(s): 273 - 286
  02/01/2011 Authors: Chandele A; Mukerjee P; Das G; Ahmed R; Chauhan VS
• Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection.
  J Exp Med Volume: 208 Page(s): 181 - 193
  01/17/2011 Authors: Wrammert J; Koutsonanos D; Li G-M; Edupuganti S; Sui J; Morrissey M; McCausland M; Skountzou I; Hornig M; Lipkin WI
• Role of PD-1 in regulating T-cell immunity.
  Curr Top Microbiol Immunol Volume: 350 Page(s): 17 - 37
  01/01/2011 Authors: Jin H-T; Ahmed R; Okazaki T
• From vaccines to memory and back.
  Immunity Volume: 33 Page(s): 451 - 463
  10/29/2010 Authors: Sallusto F; Lanzavecchia A; Araki K; Ahmed R
• Pathogenic virus-specific T cells cause disease during treatment with the calcineurin inhibitor FK506: implications for transplantation.
  J Exp Med Volume: 207 Page(s): 2355 - 2367
  10/25/2010 Authors: Araki K; Gangappa S; Dillehay DL; Rouse BT; Larsen CP; Ahmed R
• Making memories that last a lifetime: heritable functions of self-renewing memory CD8 T cells.
  Int Immunol Volume: 22 Page(s): 797 - 803
  10/01/2010 Authors: Youngblood B; Davis CW; Ahmed R
• Homeostatic turnover of virus-specific memory CD8 T cells occurs stochastically and is independent of CD4 T cell help.
  J Immunol Volume: 185 Page(s): 3436 - 3444
  09/15/2010 Authors: Choo DK; Murali-Krishna K; Anita R; Ahmed R
• The 2010 scientific strategic plan of the Global HIV Vaccine Enterprise.
  Nat Med Volume: 16 Page(s): 981 - 989
  09/01/2010 Authors: Council of the Global HIV Vaccine Enterprise
• Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection.
  Proc Natl Acad Sci U S A Volume: 107 Page(s): 14733 - 14738
  08/17/2010 Authors: Jin H-T; Anderson AC; Tan WG; West EE; Ha S-J; Araki K; Freeman GJ; Kuchroo VK; Ahmed R
• Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses.
  J Immunol Volume: 185 Page(s): 2004 - 2008
  08/15/2010 Authors: Ferrer IR; Wagener ME; Robertson JM; Turner AP; Araki K; Ahmed R; Kirk AD; Larsen CP; Ford ML
• Qualitatively different memory CD8+ T cells are generated after lymphocytic choriomeningitis virus and influenza virus infections.
  J Immunol Volume: 185 Page(s): 2182 - 2190
  08/15/2010 Authors: Mueller SN; Langley WA; Li G; Garca-Sastre A; Webby RJ; Ahmed R
• PD-L1 has distinct functions in hematopoietic and nonhematopoietic cells in regulating T cell responses during chronic infection in mice.
  J Clin Invest Volume: 120 Page(s): 2508 - 2515
  07/01/2010 Authors: Mueller SN; Vanguri VK; Ha S-J; West EE; Keir ME; Glickman JN; Sharpe AH; Ahmed R
• The role of mTOR in memory CD8 T-cell differentiation.
  Immunol Rev Volume: 235 Page(s): 234 - 243
  05/01/2010 Authors: Araki K; Youngblood B; Ahmed R
• Signatures of Cytomegalovirus Protective Immunity in the Setting of Immunosuppression
  Volume: 10 Page(s): 480 - 480
  04/01/2010 Authors: Mehta AK; McClausland M; Mulupuri P; Cheeseman J; Martens C; Ahmed R; Larsen CP
• Features of responding T cells in cancer and chronic infection.
  Curr Opin Immunol Volume: 22 Page(s): 223 - 230
  04/01/2010 Authors: Kim PS; Ahmed R
• IL-2 therapy synergizes with PD-L1 blockade to rescue exhausted CD8+T cells during chronic viral infection
  JOURNAL OF IMMUNOLOGY Volume: 184
  04/01/2010 Authors: West E; Ha S-J; Tan W; Jin H-T; Freeman G; Smith K; Ahmed R
• Improved T cell restoration by depletion of T regulatory (Treg) cells followed by PD-1 blockade during chronic infection
  JOURNAL OF IMMUNOLOGY Volume: 184
  04/01/2010 Authors: Penaloza-MacMaster P; Araki K; Ahmed R; West E; Freeman G; Rudenski A; Tan W; Jin H; Aubert R; Omara L
• Dynamic T cell migration program provides resident memory within intestinal epithelium.
  J Exp Med Volume: 207 Page(s): 553 - 564
  03/15/2010 Authors: Masopust D; Choo D; Vezys V; Wherry EJ; Duraiswamy J; Akondy R; Wang J; Casey KA; Barber DL; Kawamura KS
• Immunization with live attenuated influenza viruses that express altered NS1 proteins results in potent and protective memory CD8+ T-cell responses.
  J Virol Volume: 84 Page(s): 1847 - 1855
  02/01/2010 Authors: Mueller SN; Langley WA; Carnero E; Garca-Sastre A; Ahmed R
• Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo.
  Immunity Volume: 32 Page(s): 91 - 103
  01/29/2010 Authors: Kalia V; Sarkar S; Subramaniam S; Haining WN; Smith KA; Ahmed R
• Signatures of Cytomegalovirus Protective Immunity in the Setting of Immunosuppression
  Volume: 10 Page(s): 36 - 36
  01/01/2010 Authors: Mehta AK; McCausland M; Mulupuri P; Cheeseman J; Martens C; Ahmed R; Larsen CP
• CD8 T-cell memory differentiation during acute and chronic viral infections.
  Adv Exp Med Biol Volume: 684 Page(s): 79 - 95
  01/01/2010 Authors: Kalia V; Sarkar S; Ahmed R
• The yellow fever virus vaccine induces a broad and polyfunctional human memory CD8+ T cell response.
  J Immunol Volume: 183 Page(s): 7919 - 7930
  12/15/2009 Authors: Akondy RS; Monson ND; Miller JD; Edupuganti S; Teuwen D; Wu H; Quyyumi F; Garg S; Altman JD; Del Rio C
• Clinical applications of intravenous immunoglobulins (IVIg)--beyond immunodeficiencies and neurology.
  Volume: 158 Suppl 1 Page(s): 23 - 33
  12/01/2009 Authors: Hartung H-P; Mouthon L; Ahmed R; Jordan S; Laupland KB; Jolles S
• T-cell reconstitution without T-cell immunopathology in two models of T-cell-mediated tissue destruction.
  Immunology Volume: 128 Page(s): 164 - 171
  10/01/2009 Authors: Penaloza-MacMaster P; Masopust D; Ahmed R
• The precursors of memory: models and controversies.
  Nat Rev Immunol Volume: 9 Page(s): 662 - 668
  09/01/2009 Authors: Ahmed R; Bevan MJ; Reiner SL; Fearon DT
• Viral hemorrhagic fevers are often cited by the emerging infections and bioterrorism scientific communities. Introduction.
  Ann N Y Acad Sci Volume: 1171 Suppl 1 Page(s): E1 - E4
  09/01/2009 Authors: Rollin PE
• Redefining chronic viral infection.
  Cell Volume: 138 Page(s): 30 - 50
  07/10/2009 Authors: Virgin HW; Wherry EJ; Ahmed R
• mTOR regulates memory CD8 T-cell differentiation.
  Nature Volume: 460 Page(s): 108 - 112
  07/02/2009 Authors: Araki K; Turner AP; Shaffer VO; Gangappa S; Keller SA; Bachmann MF; Larsen CP; Ahmed R
• High antigen levels are the cause of T cell exhaustion during chronic viral infection.
  Proc Natl Acad Sci U S A Volume: 106 Page(s): 8623 - 8628
  05/26/2009 Authors: Mueller SN; Ahmed R
• Impact of epitope escape on PD-1 expression and CD8 T-cell exhaustion during chronic infection.
  J Virol Volume: 83 Page(s): 4386 - 4394
  05/01/2009 Authors: Blattman JN; Wherry EJ; Ha S-J; van der Most RG; Ahmed R
• Memory B cells are required to maintain long-lived plasma cells in mice following viral infections
  JOURNAL OF IMMUNOLOGY Volume: 182
  04/01/2009 Authors: Langley WA; Mueller SN; Ahmed R
• PD-1 localization in the immunological synapse is different in exhausted as compared to effector LCMV specific CD8 T cells
  JOURNAL OF IMMUNOLOGY Volume: 182
  04/01/2009 Authors: Duraiswamy J; Pryshchep S; Ha S-J; Goronzy JJ; Ahmed R
• Combining PDL-1 blockade with agonistic antibodies against 4-1BB enhances T cell restoration after chronic LCMV infection
  JOURNAL OF IMMUNOLOGY Volume: 182
  04/01/2009 Authors: MacMaster PP; Vezys V; Ha S-J; Konieczny B; Barber D; Mittler R; Ahmed R
• Aberrant DNA demethylation of PD-1 during chronic viral infection
  JOURNAL OF IMMUNOLOGY Volume: 182
  04/01/2009 Authors: Ben Y; Oestreich KJ; Ha S-JJ; Duraiswamy J; Akondy R; Boss JM; Ahmed R
• Molecular signature of human virus specific effector CD8+T cells
  JOURNAL OF IMMUNOLOGY Volume: 182
  04/01/2009 Authors: Akondy RS; Miller JD; Doho G; Wu H; Zilliox M; de Rio C; Mulligan MJ; Edupuganti S; Haining WN; Ahmed R
• Visualizing antigen-specific and infected cells in situ predicts outcomes in early viral infection.
  Science Volume: 323 Page(s): 1726 - 1729
  03/27/2009 Authors: Li Q; Skinner PJ; Ha S-J; Duan L; Mattila TL; Hage A; White C; Barber DL; O'Mara L; Southern PJ
• Enhancing SIV-specific immunity in vivo by PD-1 blockade.
  Nature Volume: 458 Page(s): 206 - 210
  03/12/2009 Authors: Velu V; Titanji K; Zhu B; Husain S; Pladevega A; Lai L; Vanderford TH; Chennareddi L; Silvestri G; Freeman GJ
• Human immune memory to yellow fever and smallpox vaccination.
  J Clin Immunol Volume: 29 Page(s): 151 - 157
  03/01/2009 Authors: Wrammert J; Miller J; Akondy R; Ahmed R
• Requirement of B cells for generating CD4+ T cell memory.
  J Immunol Volume: 182 Page(s): 1868 - 1876
  02/15/2009 Authors: Whitmire JK; Asano MS; Kaech SM; Sarkar S; Hannum LG; Shlomchik MJ; Ahmed R
• Memory CD8 T-cell compartment grows in size with immunological experience.
  Nature Volume: 457 Page(s): 196 - 199
  01/08/2009 Authors: Vezys V; Yates A; Casey KA; Lanier G; Ahmed R; Antia R; Masopust D
• Comments from the Organizing Committee
  Volume: 1171 Page(s): E4 - E5
  01/01/2009 Authors: Ansari A; Jabbar A; Parslow TG; Ahmed R
• Frequency and phenotype of human immunodeficiency virus envelope-specific B cells from patients with broadly cross-neutralizing antibodies.
  J Virol Volume: 83 Page(s): 188 - 199
  01/01/2009 Authors: Doria-Rose NA; Klein RM; Manion MM; O'Dell S; Phogat A; Chakrabarti B; Hallahan CW; Migueles SA; Wrammert J; Ahmed R
• Rapid generation of fully human monoclonal antibodies specific to a vaccinating antigen.
  Nat Protoc Volume: 4 Page(s): 372 - 384
  01/01/2009 Authors: Smith K; Garman L; Wrammert J; Zheng N-Y; Capra JD; Ahmed R; Wilson PC
• Systems biology approach predicts immunogenicity of the yellow fever vaccine in humans.
  Nat Immunol Volume: 10 Page(s): 116 - 125
  01/01/2009 Authors: Querec TD; Akondy RS; Lee EK; Cao W; Nakaya HI; Teuwen D; Pirani A; Gernert K; Deng J; Marzolf B
• Immunological Memory: Remembering Our Pathogens
  Volume: 112 Page(s): 1348 - 1348
  11/16/2008 Authors: Ahmed R
• NFATc1 regulates PD-1 expression upon T cell activation.
  J Immunol Volume: 181 Page(s): 4832 - 4839
  10/01/2008 Authors: Oestreich KJ; Yoon H; Ahmed R; Boss JM
• Cholera toxin-specific memory B cell responses are induced in patients with dehydrating diarrhea caused by Vibrio cholerae O1.
  J Infect Dis Volume: 198 Page(s): 1055 - 1061
  10/01/2008 Authors: Jayasekera CR; Harris JB; Bhuiyan S; Chowdhury F; Khan AI; Faruque ASG; Larocque RC; Ryan ET; Ahmed R; Qadri F
• Case of yellow fever vaccine--associated viscerotropic disease with prolonged viremia, robust adaptive immune responses, and polymorphisms in CCR5 and RANTES genes.
  J Infect Dis Volume: 198 Page(s): 500 - 507
  08/15/2008 Authors: Pulendran B; Miller J; Querec TD; Akondy R; Moseley N; Laur O; Glidewell J; Monson N; Zhu T; Zhu H
• Lymphoid stroma in the initiation and control of immune responses.
  Immunol Rev Volume: 224 Page(s): 284 - 294
  08/01/2008 Authors: Mueller SN; Ahmed R
• Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells.
  J Immunol Volume: 181 Page(s): 1859 - 1868
  08/01/2008 Authors: Haining WN; Ebert BL; Subrmanian A; Wherry EJ; Eichbaum Q; Evans JW; Mak R; Rivoli S; Pretz J; Angelosanto J
• Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections.
  Immunol Rev Volume: 223 Page(s): 317 - 333
  06/01/2008 Authors: Ha S-J; West EE; Araki K; Smith KA; Ahmed R
• Unraveling the role of PD-1/PD-L interactions in persistent hepatotropic infections: potential for therapeutic application?
  Gastroenterology Volume: 134 Page(s): 2168 - 2171
  06/01/2008 Authors: Radziewicz H; Hanson HL; Ahmed R; Grakoui A
• Rapid cloning of high-affinity human monoclonal antibodies against influenza virus.
  Nature Volume: 453 Page(s): 667 - 671
  05/29/2008 Authors: Wrammert J; Smith K; Miller J; Langley WA; Kokko K; Larsen C; Zheng N-Y; Mays I; Garman L; Helms C
• Human effector and memory CD8+ T cell responses to smallpox and yellow fever vaccines.
  Immunity Volume: 28 Page(s): 710 - 722
  05/01/2008 Authors: Miller JD; van der Most RG; Akondy RS; Glidewell JT; Albott S; Masopust D; Murali-Krishna K; Mahar PL; Edupuganti S; Lalor S
• Incidence and prognosis of Pneumocystis jiroveci pneumonia following kidney transplantation in the modern era
  Volume: 8 Page(s): 526 - 526
  05/01/2008 Authors: Kim HJ; Wrammert J; Larsen CP; Ahmed R; Kokko KE
• Influenza vaccination in renal transplant patients: A defect in peripheral antibody secreting cells (ASC)
  Volume: 8 Page(s): 526 - 526
  05/01/2008 Authors: Kim HJ; Wrammer J; Larsen CP; Ahmed R; Kokko KE
• Maintenance of serological memory.
  Biol Chem Volume: 389 Page(s): 537 - 539
  05/01/2008 Authors: Wrammert J; Ahmed R
• Marked Expansion of Foxp3+, Vbeta5+Regulatory T cells during Chronic Lymphocytic Choriomeningitis Virus (LCMV) Infection
  FASEB JOURNAL Volume: 22
  04/01/2008 Authors: Punkosdy G; Ahmed R; Shevach E
• Immune responsiveness and protective immunity after transplantation.
  Transpl Int Volume: 21 Page(s): 293 - 303
  04/01/2008 Authors: Gangappa S; Kokko KE; Carlson LM; Gourley T; Newell KA; Pearson TC; Ahmed R; Larsen CP
• The role of CD4 T cell help in restoring function of exhausted CD8 T cells during chronic infection
  FASEB JOURNAL Volume: 22
  04/01/2008 Authors: Aubert RD; Sarkar S; Ahmed R
• Early CD8 T cell proliferative heterogeneity entails diverse memory differentiation programs
  FASEB JOURNAL Volume: 22
  04/01/2008 Authors: Kalia V; Sarkar S; Kaech S; Ahmed R
• ST6Gal-I gene expression is required for optimal Ag-specific CD8 T cell expansion in vivo
  FASEB JOURNAL Volume: 22
  04/01/2008 Authors: Onami TM; Patel JR; Zeng J; Baum LG; Ahmed R
• CD8 T cell responses to live, viral Yellow fever vaccine in humans
  FASEB JOURNAL Volume: 22
  04/01/2008 Authors: Akondy R; Miller J; Monson N; Wu H; Quyyumi F; Mulligan M; Teuwen D; Altman J; Ahmed R
• Defective influenza-specific B cell responses in mice lacking expression of ST6Gal-I
  FASEB JOURNAL Volume: 22
  04/01/2008 Authors: Onami TM; Zeng J; Joo H-M; Wrammert JP; Ahmed R; Sangster MY
• Protective Immunity in Transplant Recipients
  Volume: 22
  04/01/2008 Authors: Mulupuri P; Gourley T; Popkowski A; Mehta A; Begley B; Breeden C; Larsen C; Ahmed R
• Diminished primary CD8 T cell response to viral infection during protein energy malnutrition in mice is due to changes in microenvironment and low numbers of viral-specific CD8 T cell precursors.
  J Nutr Volume: 138 Page(s): 806 - 812
  04/01/2008 Authors: Chatraw JH; Wherry EJ; Ahmed R; Kapasi ZF
• T cell migration and memory differentiation within the mouse intestinal mucosa in response to infection
  FASEB JOURNAL Volume: 22
  04/01/2008 Authors: Masopust D; Vezys V; Wherry EJ; Ahmed R
• PD-1 negatively regulates CD8 T cell-mediated mucosal autoimmunity
  FASEB JOURNAL Volume: 22
  04/01/2008 Authors: Vezys V; Masopust D; Sharpe A; Freeman G; Newell K; Ahmed R
• Enhancing therapeutic vaccination by blocking PD-1-mediated inhibitory signals during chronic infection.
  J Exp Med Volume: 205 Page(s): 543 - 555
  03/17/2008 Authors: Ha S-J; Mueller SN; Wherry EJ; Barber DL; Aubert RD; Sharpe AH; Freeman GJ; Ahmed R
• Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates.
  J Exp Med Volume: 205 Page(s): 625 - 640
  03/17/2008 Authors: Sarkar S; Kalia V; Haining WN; Konieczny BT; Subramaniam S; Ahmed R
• Localization of CD8+ cells specific for hepatitis B virus surface protein in the liver of immunized mice.
  J Med Virol Volume: 80 Page(s): 225 - 232
  02/01/2008 Authors: Qu D; Lanier G; Yuan ZH; Wen YM; Howard CR; Ahmed R
• Fine-tuning CD4+ central memory T cell heterogeneity by strength of stimulation.
  Eur J Immunol Volume: 38 Page(s): 15 - 19
  01/01/2008 Authors: Kalia V; Sarkar S; Ahmed R
• Revisiting estimates of CTL killing rates in vivo.
  PLoS One Volume: 2 Page(s): e1301
  12/12/2007 Authors: Yates A; Graw F; Barber DL; Ahmed R; Regoes RR; Antia R
• Strength of stimulus and clonal competition impact the rate of memory CD8 T cell differentiation.
  J Immunol Volume: 179 Page(s): 6704 - 6714
  11/15/2007 Authors: Sarkar S; Teichgrber V; Kalia V; Polley A; Masopust D; Harrington LE; Ahmed R; Wherry EJ
• A brief history of CD8 T cells.
  Eur J Immunol Volume: 37 Suppl 1 Page(s): S103 - S110
  11/01/2007 Authors: Masopust D; Vezys V; Wherry EJ; Ahmed R
• Nonimmunosuppressive chemotherapy: EM011-treated mice mount normal T-cell responses to an acute lymphocytic choriomeningitis virus infection.
  Mol Cancer Ther Volume: 6 Page(s): 2891 - 2899
  11/01/2007 Authors: Aneja R; Kalia V; Ahmed R; Joshi HC
• Protective immunity and susceptibility to infectious diseases: lessons from the 1918 influenza pandemic.
  Nat Immunol Volume: 8 Page(s): 1188 - 1193
  11/01/2007 Authors: Ahmed R; Oldstone MBA; Palese P
• Monkeypox-induced immunity and failure of childhood smallpox vaccination to provide complete protection.
  Clin Vaccine Immunol Volume: 14 Page(s): 1318 - 1327
  10/01/2007 Authors: Karem KL; Reynolds M; Hughes C; Braden Z; Nigam P; Crotty S; Glidewell J; Ahmed R; Amara R; Damon IK
• Normal establishment of virus-specific memory CD8 T cell pool following primary infection during pregnancy.
  J Immunol Volume: 179 Page(s): 4383 - 4389
  10/01/2007 Authors: Constantin CM; Masopust D; Gourley T; Grayson J; Strickland OL; Ahmed R; Bonney EA
• Molecular signature of CD8+ T cell exhaustion during chronic viral infection.
  Immunity Volume: 27 Page(s): 670 - 684
  10/01/2007 Authors: Wherry EJ; Ha S-J; Kaech SM; Haining WN; Sarkar S; Kalia V; Subramaniam S; Blattman JN; Barber DL; Ahmed R
• Immune suppression or enhancement by CD137 T cell costimulation during acute viral infection is time dependent.
  J Clin Invest Volume: 117 Page(s): 3029 - 3041
  10/01/2007 Authors: Zhang B; Maris CH; Foell J; Whitmire J; Niu L; Song J; Kwon BS; Vella AT; Ahmed R; Jacob J
• Viral targeting of fibroblastic reticular cells contributes to immunosuppression and persistence during chronic infection.
  Proc Natl Acad Sci U S A Volume: 104 Page(s): 15430 - 15435
  09/25/2007 Authors: Mueller SN; Matloubian M; Clemens DM; Sharpe AH; Freeman GJ; Gangappa S; Larsen CP; Ahmed R
• Fully MHC-disparate mixed hemopoietic chimeras show specific defects in the control of chronic viral infections.
  J Immunol Volume: 179 Page(s): 2616 - 2626
  08/15/2007 Authors: Koehn BH; Williams MA; Borom K; Gangappa S; Pearson TC; Ahmed R; Larsen CP
• Regulation of homeostatic chemokine expression and cell trafficking during immune responses.
  Science Volume: 317 Page(s): 670 - 674
  08/03/2007 Authors: Mueller SN; Hosiawa-Meagher KA; Konieczny BT; Sullivan BM; Bachmann MF; Locksley RM; Ahmed R; Matloubian M
• Duration of antigenic stimulation dictates commitment to central and effector memory lineages early during immune expansion
  JOURNAL OF MEDICAL PRIMATOLOGY Volume: 36 Page(s): 297 - 297
  08/01/2007 Authors: Sarkar S; Kalia V; Konieczny BT; Subramaniam S; Ahmed R
• Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination.
  J Virol Volume: 81 Page(s): 5819 - 5828
  06/01/2007 Authors: Velu V; Kannanganat S; Ibegbu C; Chennareddi L; Villinger F; Freeman GJ; Ahmed R; Amara RR
• Proteome-wide analysis of the serological response to vaccinia and smallpox.
  Proteomics Volume: 7 Page(s): 1678 - 1686
  05/01/2007 Authors: Davies DH; Molina DM; Wrammert J; Miller J; Hirst S; Mu Y; Pablo J; Unal B; Nakajima-Sasaki R; Liang X
• PD-1 expression on memory CD8 and CD4 T-cell subsets in healthy humans
  JOURNAL OF IMMUNOLOGY Volume: 178
  04/01/2007 Authors: Duraiswamy J; Miller JD; Masopust D; Ibegbu CC; Wu H; Freeman GJ; Ahmed R
• Length of Antigenic Stimulation During Expansion Dictates Commitment to CD8 T Cell Memory Subsets
  JOURNAL OF IMMUNOLOGY Volume: 178
  04/01/2007 Authors: Sarkar S; Kalia V; Haining WN; Konieczny BT; Subramaniam S; Ahmed R
• Early CD8 T cell proliferative heterogeneity entails diverse memory differentiation programs
  JOURNAL OF IMMUNOLOGY Volume: 178
  04/01/2007 Authors: Kalia V; Sarkar S; Kaech SM; Ahmed R
• Functionally impaired T cell-dependent immunopathology in FK506-treated mice with LCMV infection
  JOURNAL OF IMMUNOLOGY Volume: 178
  04/01/2007 Authors: Araki K; Gangappa S; Rouse BT; Larsen CP; Ahmed R
• Antigen-specific CD4+ T cells recognize epitopes of protective antigen following vaccination with an anthrax vaccine.
  Infect Immun Volume: 75 Page(s): 1852 - 1860
  04/01/2007 Authors: Laughlin EM; Miller JD; James E; Fillos D; Ibegbu CC; Mittler RS; Akondy R; Kwok W; Ahmed R; Nepom G
• The function of programmed cell death 1 and its ligands in regulating autoimmunity and infection.
  Nat Immunol Volume: 8 Page(s): 239 - 245
  03/01/2007 Authors: Sharpe AH; Wherry EJ; Ahmed R; Freeman GJ
• Liver-infiltrating lymphocytes in chronic human hepatitis C virus infection display an exhausted phenotype with high levels of PD-1 and low levels of CD127 expression.
  J Virol Volume: 81 Page(s): 2545 - 2553
  03/01/2007 Authors: Radziewicz H; Ibegbu CC; Fernandez ML; Workowski KA; Obideen K; Wehbi M; Hanson HL; Steinberg JP; Masopust D; Wherry EJ
• Quantitating the magnitude of the lymphocytic choriomeningitis virus-specific CD8 T-cell response: it is even bigger than we thought.
  J Virol Volume: 81 Page(s): 2002 - 2011
  02/01/2007 Authors: Masopust D; Murali-Krishna K; Ahmed R
• Estimation of the rate of killing by cytotoxic T lymphocytes in vivo.
  Proc Natl Acad Sci U S A Volume: 104 Page(s): 1599 - 1603
  01/30/2007 Authors: Regoes RR; Barber DL; Ahmed R; Antia R
• All memory lymphocytes share a common differentiation program.
  Volume: 108 Page(s): 259A - 259A
  11/16/2006 Authors: Haining WN; Ebert B; Subramanian A; Wherry EJ; Evans J; Mak R; Rivoli S; Angelosanto J; Pretz J; Kaech S
• Hypogammaglobulinemia and exacerbated CD8 T-cell-mediated immunopathology in SAP-deficient mice with chronic LCMV infection mimics human XLP disease.
  Blood Volume: 108 Page(s): 3085 - 3093
  11/01/2006 Authors: Crotty S; McCausland MM; Aubert RD; Wherry EJ; Ahmed R
• Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection.
  J Exp Med Volume: 203 Page(s): 2263 - 2269
  10/02/2006 Authors: Vezys V; Masopust D; Kemball CC; Barber DL; O'Mara LA; Larsen CP; Pearson TC; Ahmed R; Lukacher AE
• Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade.
  J Exp Med Volume: 203 Page(s): 2223 - 2227
  10/02/2006 Authors: Freeman GJ; Wherry EJ; Ahmed R; Sharpe AH
• Turning on the off switch: regulation of anti-viral T cell responses in the liver by the PD-1/PD-L1 pathway.
  J Hepatol Volume: 45 Page(s): 468 - 472
  10/01/2006 Authors: Grakoui A; John Wherry E; Hanson HL; Walker C; Ahmed R
• HIV-specific CD8 T cells express low levels of IL-7Ralpha: implications for HIV-specific T cell memory.
  Virology Volume: 353 Page(s): 366 - 373
  09/30/2006 Authors: Wherry EJ; Day CL; Draenert R; Miller JD; Kiepiela P; Woodberry T; Brander C; Addo M; Klenerman P; Ahmed R
• PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.
  Nature Volume: 443 Page(s): 350 - 354
  09/21/2006 Authors: Day CL; Kaufmann DE; Kiepiela P; Brown JA; Moodley ES; Reddy S; Mackey EW; Miller JD; Leslie AJ; DePierres C
• Stimulation history dictates memory CD8 T cell phenotype: implications for prime-boost vaccination.
  J Immunol Volume: 177 Page(s): 831 - 839
  07/15/2006 Authors: Masopust D; Ha S-J; Vezys V; Ahmed R
• How does cross-reactive stimulation affect the longevity of CD8+ T cell memory?
  PLoS Comput Biol Volume: 2 Page(s): e55
  06/09/2006 Authors: Ganusov VV; Pilyugin SS; Ahmed R; Antia R
• Differentiation of memory B and T cells.
  Curr Opin Immunol Volume: 18 Page(s): 255 - 264
  06/01/2006 Authors: Kalia V; Sarkar S; Gourley TS; Rouse BT; Ahmed R
• Memory T cells in mice and humans share a common molecular program of differentiation regardless of phenotype, lineage or species
  Volume: 176 Page(s): S303 - S303
  04/01/2006 Authors: Haining WN; Ebert B; Subramanian A; Kaech S; Ahmed R; Nadler L; Wherry EJ; Golub T
• Impaired memory CD8 T cell development in the absence of MBD2
  Volume: 176 Page(s): S303 - S304
  04/01/2006 Authors: Kersh EN; Ahmed R
• Preferential accumulation of effector memory CD8 T cells following secondary and tertiary infections: implications for prime-boost vaccination and memory differentiation
  Volume: 176 Page(s): S118 - S118
  04/01/2006 Authors: Masopust D; Ha S-J; Vezys V; Ahmed R
• Serological profiling after vaccination against smallpox reveals heterogeneity and redundancy within the antibody response.
  Volume: 176 Page(s): S73 - S73
  04/01/2006 Authors: Davies DH; Wrammert J; Molina D; Miller J; Hirst S; Ahmed R; Villarreal LP; Felgner P
• Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells.
  J Immunol Volume: 176 Page(s): 4083 - 4093
  04/01/2006 Authors: Kersh EN; Fitzpatrick DR; Murali-Krishna K; Shires J; Speck SH; Boss JM; Ahmed R
• Understanding CD8 T cell memory lineage decisions
  Volume: 176 Page(s): S123 - S123
  04/01/2006 Authors: Sarkar S; Kalia V; Ahmed R
• Properties of antigen-specific CD4 T cells during chronic viral infection
  Volume: 176 Page(s): S125 - S125
  04/01/2006 Authors: Vezys V; Barber DL; Latner DR; Ahmed R
• Mechanisms regulating CD8 T cell memory differentiation
  Volume: 176 Page(s): S117 - S117
  04/01/2006 Authors: Kalia V; Sarkar S; Kaech SM; Harrington LE; Ahmed R
• Patients, pathogens, and protective immunity: the relevance of virus-induced alloreactivity in transplantation.
  J Immunol Volume: 176 Page(s): 2691 - 2696
  03/01/2006 Authors: Koehn B; Gangappa S; Miller JD; Ahmed R; Larsen CP
• Translating innate immunity into immunological memory: implications for vaccine development.
  Cell Volume: 124 Page(s): 849 - 863
  02/24/2006 Authors: Pulendran B; Ahmed R
• Yellow fever vaccine YF-17D activates multiple dendritic cell subsets via TLR2, 7, 8, and 9 to stimulate polyvalent immunity.
  J Exp Med Volume: 203 Page(s): 413 - 424
  02/20/2006 Authors: Querec T; Bennouna S; Alkan S; Laouar Y; Gorden K; Flavell R; Akira S; Ahmed R; Pulendran B
• Cutting edge: gut microenvironment promotes differentiation of a unique memory CD8 T cell population.
  J Immunol Volume: 176 Page(s): 2079 - 2083
  02/15/2006 Authors: Masopust D; Vezys V; Wherry EJ; Barber DL; Ahmed R
• Restoring function in exhausted CD8 T cells during chronic viral infection.
  Nature Volume: 439 Page(s): 682 - 687
  02/09/2006 Authors: Barber DL; Wherry EJ; Masopust D; Zhu B; Allison JP; Sharpe AH; Freeman GJ; Ahmed R
• Memory T-cells in mice and humans share a common molecular program of differentiation regardless of phenotype, lineage or species.
  Volume: 119 Page(s): S182 - S183
  01/01/2006 Authors: Haining WN; Ebert B; Subramanian A; Kaech S; Ahmed R; Nadler L; Wherry EJ; Golub T
• Noscapine inhibits tumor progression by selectively inducing apoptosis in vitro and in vivo without compromising immune surveillance: Implications for combining chemotherapy and immunotherapy.
  Volume: 11 Page(s): 9088S - 9089S
  12/15/2005 Authors: Aneja R; Kaalia V; Ahmed R; Joshi HC
• Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin.
  Nat Immunol Volume: 6 Page(s): 1236 - 1244
  12/01/2005 Authors: Intlekofer AM; Takemoto N; Wherry EJ; Longworth SA; Northrup JT; Palanivel VR; Mullen AC; Gasink CR; Kaech SM; Miller JD
• Chimeric influenza virus hemagglutinin proteins containing large domains of the Bacillus anthracis protective antigen: protein characterization, incorporation into infectious influenza viruses, and antigenicity.
  J Virol Volume: 79 Page(s): 10003 - 10012
  08/01/2005 Authors: Li Z-N; Mueller SN; Ye L; Bu Z; Yang C; Ahmed R; Steinhauer DA
• Identification and characterization of Shigella boydii 20 serovar nov., a new and emerging Shigella serotype.
  J Med Microbiol Volume: 54 Page(s): 741 - 748
  08/01/2005 Authors: Woodward DL; Clark CG; Caldeira RA; Ahmed R; Soule G; Bryden L; Tabor H; Melito P; Foster R; Walsh J
• Low CD8 T-cell proliferative potential and high viral load limit the effectiveness of therapeutic vaccination.
  J Virol Volume: 79 Page(s): 8960 - 8968
  07/01/2005 Authors: Wherry EJ; Blattman JN; Ahmed R
• Differentiation of CD8 T cells in response to acute and chronic viral infections: implications for HIV vaccine development.
  Curr Drug Targets Infect Disord Volume: 5 Page(s): 121 - 129
  06/01/2005 Authors: Miller JD; Masopust D; Wherry EJ; Kaech S; Silvestri G; Ahmed R
• BCL6b mediates the enhanced magnitude of the secondary response of memory CD8+ T lymphocytes.
  Proc Natl Acad Sci U S A Volume: 102 Page(s): 7418 - 7425
  05/24/2005 Authors: Manders PM; Hunter PJ; Telaranta AI; Carr JM; Marshall JL; Carrasco M; Murakami Y; Palmowski MJ; Cerundolo V; Kaech SM
• CD8-mediated protection against Ebola virus infection is perforin dependent.
  J Immunol Volume: 174 Page(s): 4198 - 4202
  04/01/2005 Authors: Gupta M; Greer P; Mahanty S; Shieh W-J; Zaki SR; Ahmed R; Rollin PE
• The CD4 molecule on CD8+ T lymphocytes directly enhances the immune response to viral and cellular antigens.
  Proc Natl Acad Sci U S A Volume: 102 Page(s): 3794 - 3799
  03/08/2005 Authors: Kitchen SG; Whitmire JK; Jones NR; Galic Z; Kitchen CMR; Ahmed R; Zack JA
• Failure to maintain homeostatic proliferation of viral-specific memory CD8 T cells during protein calorie malnutrition (PCM)
  Volume: 19 Page(s): A1466 - A1466
  03/07/2005 Authors: Chatraw JH; Becker TC; Wherry EJ; Ahmed R; Kapasi Z
• Inability to control a chronic viral infection and exacerbated immunopathology are associated with defective T and B cell responses in SAP-deficient mice
  Volume: 19 Page(s): A399 - A399
  03/04/2005 Authors: Crotty S; McCausland MM; Wherry EJ; Ahmed R
• Antigen-independent memory CD8 T cells do not develop during chronic viral infection
  Volume: 19 Page(s): A394 - A394
  03/04/2005 Authors: Wherry EJ; Barber DL; Kaech SM; Blattman JN; Ahmed R
• PD-L1 blockade restores function to CD8 T cells during chronic viral infection
  Volume: 19 Page(s): A893 - A893
  03/04/2005 Authors: Barber DL; Wherry EJ; Masopust D; Greenwald RJ; Sharpe AH; Freeman GJ; Ahmed R
• LCMV clone-13 infects fibroblastic reticular cells of the conduit system in the spleen
  Volume: 19 Page(s): A966 - A966
  03/04/2005 Authors: Mueller S; Clemens D; Ahmed R
• Intestinal mucosa modulates memory CD8 T cell differentiation program
  Volume: 19 Page(s): A406 - A406
  03/04/2005 Authors: Masopust D; Vezys V; Barber DL; Ahmed R
• Ongoing virus-specific naive CD8 T cell development, priming and expansion during the chronic stage of persistent viral infections
  Volume: 19 Page(s): A395 - A395
  03/04/2005 Authors: Vezys V; Kemball CC; Masopust D; Barber DL; Lee E; Larson C; Ahmed R; Lukacher AE
• Quantifying cell turnover using CFSE data.
  J Immunol Methods Volume: 298 Page(s): 183 - 200
  03/01/2005 Authors: Ganusov VV; Pilyugin SS; de Boer RJ; Murali-Krishna K; Ahmed R; Antia R
• The role of models in understanding CD8+ T-cell memory.
  Nat Rev Immunol Volume: 5 Page(s): 101 - 111
  02/01/2005 Authors: Antia R; Ganusov VV; Ahmed R
• Bone marrow is a preferred site for homeostatic proliferation of memory CD8 T cells.
  J Immunol Volume: 174 Page(s): 1269 - 1273
  02/01/2005 Authors: Becker TC; Coley SM; Wherry EJ; Ahmed R
• Antigen-independent memory CD8 T cells do not develop during chronic viral infection.
  Proc Natl Acad Sci U S A Volume: 101 Page(s): 16004 - 16009
  11/09/2004 Authors: Wherry EJ; Barber DL; Kaech SM; Blattman JN; Ahmed R
• The selective increase in caspase-3 expression in effector but not memory T cells allows susceptibility to apoptosis.
  J Immunol Volume: 173 Page(s): 5425 - 5433
  11/01/2004 Authors: Sabbagh L; Kaech SM; Bourbonnire M; Woo M; Cohen LY; Haddad EK; Labrecque N; Ahmed R; Skaly R-P
• Generation and maintenance of immunological memory.
  Semin Immunol Volume: 16 Page(s): 323 - 333
  10/01/2004 Authors: Gourley TS; Wherry EJ; Masopust D; Ahmed R
• Enhanced expression of cell cycle regulatory genes in virus-specific memory CD8+ T cells.
  J Virol Volume: 78 Page(s): 10953 - 10959
  10/01/2004 Authors: Latner DR; Kaech SM; Ahmed R
• Immune responses to Bacillus anthracis protective antigen in patients with bioterrorism-related cutaneous or inhalation anthrax.
  Volume: 190 Page(s): 1228 - 1236
  10/01/2004 Authors: Quinn CP; Dull PM; Semenova V; Li H; Crotty S; Taylor TH; Steward-Clark E; Stamey KL; Schmidt DS; Stinson KW
• Immunological memory in humans.
  Semin Immunol Volume: 16 Page(s): 197 - 203
  06/01/2004 Authors: Crotty S; Ahmed R
• Memory CD8 T-cell differentiation during viral infection.
  J Virol Volume: 78 Page(s): 5535 - 5545
  06/01/2004 Authors: Wherry EJ; Ahmed R
• Viral FLIP impairs survival of activated T cells and generation of CD8+ T cell memory.
  J Immunol Volume: 172 Page(s): 6313 - 6323
  05/15/2004 Authors: Wu Z; Roberts M; Porter M; Walker F; Wherry EJ; Kelly J; Gadina M; Silva EM; DosReis GA; Lopes MF
• The role of programming in memory T-cell development.
  Curr Opin Immunol Volume: 16 Page(s): 217 - 225
  04/01/2004 Authors: Masopust D; Kaech SM; Wherry EJ; Ahmed R
• Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus.
  Mol Cell Biol Volume: 24 Page(s): 3286 - 3294
  04/01/2004 Authors: Derjuga A; Gourley TS; Holm TM; Heng HHQ; Shivdasani RA; Ahmed R; Andrews NC; Blank V
• Selective expression of the IL-7R identifies effector CD8 T cells that give rise to long-lived memory cells
  Volume: 18 Page(s): A798 - A798
  03/24/2004 Authors: Kaech SM; Tan JT; Wherry EJ; Konieczny BT; Surh CD; Ahmed R
• vFLIP blocks the generation of functional memory CD8 cells
  Volume: 18 Page(s): A437 - A438
  03/23/2004 Authors: Wu ZQ; Roberts M; Porter MA; Wherry J; Ahmed R; Siegel RM
• The role of SAP in T cell-B cell collaboration
  Volume: 18 Page(s): A435 - A435
  03/23/2004 Authors: Yu LJ; Cannons JL; Crotty S; Siminovitch KA; Ahmed R; Schwartzberg PL
• Tracking human antigen-specific memory B cells: a sensitive and generalized ELISPOT system.
  J Immunol Methods Volume: 286 Page(s): 111 - 122
  03/01/2004 Authors: Crotty S; Aubert RD; Glidewell J; Ahmed R
• Cytosolic delivery of viral nucleoprotein by listeriolysin O-liposome induces enhanced specific cytotoxic T lymphocyte response and protective immunity.
  Mol Pharm Volume: 1 Page(s): 2 - 8
  01/12/2004 Authors: Mandal M; Kawamura KS; Wherry EJ; Ahmed R; Lee K-D
• Effects of hematopoietic chimerism on protective immunity.
  Volume: 4 Page(s): 190 - 190
  01/01/2004 Authors: Koehn B; Ahmed R; Larsen C
• Persistent infection with ebola virus under conditions of partial immunity.
  J Virol Volume: 78 Page(s): 958 - 967
  01/01/2004 Authors: Gupta M; Mahanty S; Greer P; Towner JS; Shieh W-J; Zaki SR; Ahmed R; Rollin PE
• Reflections on CD8 T-cell activation and memory.
  Immunol Res Volume: 29 Page(s): 151 - 160
  01/01/2004 Authors: Masopust D; Ahmed R
• CD43 modulates severity and onset of experimental autoimmune encephalomyelitis.
  J Immunol Volume: 171 Page(s): 6527 - 6533
  12/15/2003 Authors: Ford ML; Onami TM; Sperling AI; Ahmed R; Evavold BD
• Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells.
  Nat Immunol Volume: 4 Page(s): 1191 - 1198
  12/01/2003 Authors: Kaech SM; Tan JT; Wherry EJ; Konieczny BT; Surh CD; Ahmed R
• The rescaling method for quantifying the turnover of cell populations.
  J Theor Biol Volume: 225 Page(s): 275 - 283
  11/21/2003 Authors: Pilyugin SS; Ganusov VV; Murali-Krishna K; Ahmed R; Antia R
• Cutting edge: long-term B cell memory in humans after smallpox vaccination.
  J Immunol Volume: 171 Page(s): 4969 - 4973
  11/15/2003 Authors: Crotty S; Felgner P; Davies H; Glidewell J; Villarreal L; Ahmed R
• Changes in glycosylation-specific gene expression during memory T cell differentiation
  Volume: 13 Page(s): 882 - 883
  11/01/2003 Authors: Onami TM; Hernandez JD; Kaech SM; Baum LG; Ahmed R
• Changing immunodominance patterns in antiviral CD8 T-cell responses after loss of epitope presentation or chronic antigenic stimulation.
  Virology Volume: 315 Page(s): 93 - 102
  10/10/2003 Authors: van der Most RG; Murali-Krishna K; Lanier JG; Wherry EJ; Puglielli MT; Blattman JN; Sette A; Ahmed R
• Similarities and differences in CD4+ and CD8+ effector and memory T cell generation.
  Nat Immunol Volume: 4 Page(s): 835 - 842
  09/01/2003 Authors: Seder RA; Ahmed R
• The Bcl-2 family pro-apoptotic molecule, BNIP3 regulates activation-induced cell death of effector cytotoxic T lymphocytes.
  Immunology Volume: 110 Page(s): 10 - 17
  09/01/2003 Authors: Wan J; Martinvalet D; Ji X; Lois C; Kaech SM; Von Andrian UH; Lieberman J; Ahmed R; Manjunath N
• Protection from lethal infection is determined by innate immune responses in a mouse model of Ebola virus infection.
  Virology Volume: 312 Page(s): 415 - 424
  08/01/2003 Authors: Mahanty S; Gupta M; Paragas J; Bray M; Ahmed R; Rollin PE
• Cutting edge: rapid in vivo killing by memory CD8 T cells.
  J Immunol Volume: 171 Page(s): 27 - 31
  07/01/2003 Authors: Barber DL; Wherry EJ; Ahmed R
• TCR signal transduction in antigen-specific memory CD8 T cells.
  J Immunol Volume: 170 Page(s): 5455 - 5463
  06/01/2003 Authors: Kersh EN; Kaech SM; Onami TM; Moran M; Wherry EJ; Miceli MC; Ahmed R
• Heterologous immunity provides a potent barrier to transplantation tolerance.
  J Clin Invest Volume: 111 Page(s): 1887 - 1895
  06/01/2003 Authors: Adams AB; Williams MA; Jones TR; Shirasugi N; Durham MM; Kaech SM; Wherry EJ; Onami T; Lanier JG; Kokko KE
• Therapeutic use of IL-2 to enhance antiviral T-cell responses in vivo.
  Nat Med Volume: 9 Page(s): 540 - 547
  05/01/2003 Authors: Blattman JN; Grayson JM; Wherry EJ; Kaech SM; Smith KA; Ahmed R
• Mitochondrial potential and reactive oxygen intermediates in antigen-specific CD8+ T cells during viral infection.
  J Immunol Volume: 170 Page(s): 4745 - 4751
  05/01/2003 Authors: Grayson JM; Laniewski NG; Lanier JG; Ahmed R
• Models of CD8+ responses: 1. What is the antigen-independent proliferation program.
  J Theor Biol Volume: 221 Page(s): 585 - 598
  04/21/2003 Authors: Antia R; Bergstrom CT; Pilyugin SS; Kaech SM; Ahmed R
• Anti-CD137 treatment during the priming phase of an antiviral immune response results in CD8 T cell anergy and chronic infection
  Volume: 17 Page(s): C212 - C212
  04/14/2003 Authors: Maris CH; Foell J; McCausland M; Whitmire J; Ahmed R; Jacob J; Mittler RS
• Immunology. CD8 T cells remember with a little help.
  Science Volume: 300 Page(s): 263 - 265
  04/11/2003 Authors: Kaech SM; Ahmed R
• Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment.
  J Virol Volume: 77 Page(s): 4911 - 4927
  04/01/2003 Authors: Wherry EJ; Blattman JN; Murali-Krishna K; van der Most R; Ahmed R
• Lineage relationship and protective immunity of memory CD8 T cell subsets.
  Nat Immunol Volume: 4 Page(s): 225 - 234
  03/01/2003 Authors: Wherry EJ; Teichgrber V; Becker TC; Masopust D; Kaech SM; Antia R; von Andrian UH; Ahmed R
• Primary and secondary immunocompetence in mixed allogeneic chimeras.
  J Immunol Volume: 170 Page(s): 2382 - 2389
  03/01/2003 Authors: Williams MA; Adams AB; Walsh MB; Shirasugi N; Onami TM; Pearson TC; Ahmed R; Larsen CP
• Role of CD4 T cell help and costimulation in CD8 T cell responses during Listeria monocytogenes infection.
  J Immunol Volume: 170 Page(s): 2053 - 2063
  02/15/2003 Authors: Shedlock DJ; Whitmire JK; Tan J; MacDonald AS; Ahmed R; Shen H
• A specific role for B cells in the generation of CD8 T cell memory by recombinant Listeria monocytogenes.
  J Immunol Volume: 170 Page(s): 1443 - 1451
  02/01/2003 Authors: Shen H; Whitmire JK; Fan X; Shedlock DJ; Kaech SM; Ahmed R
• Preferential escape of subdominant CD8+ T cells during negative selection results in an altered antiviral T cell hierarchy.
  J Immunol Volume: 170 Page(s): 1231 - 1239
  02/01/2003 Authors: Slifka MK; Blattman JN; Sourdive DJD; Liu F; Huffman DL; Wolfe T; Hughes A; Oldstone MBA; Ahmed R; Von Herrath MG
• SAP is required for generating long-term humoral immunity.
  Nature Volume: 421 Page(s): 282 - 287
  01/16/2003 Authors: Crotty S; Kersh EN; Cannons J; Schwartzberg PL; Ahmed R
• Evidence for antibody-mediated enhancement of simian immunodeficiency virus (SIV) Gag antigen processing and cross presentation in SIV-infected rhesus macaques.
  J Virol Volume: 77 Page(s): 10 - 24
  01/01/2003 Authors: Villinger F; Mayne AE; Bostik P; Mori K; Jensen PE; Ahmed R; Ansari AA
• Induction of telomerase activity and maintenance of telomere length in virus-specific effector and memory CD8+ T cells.
  J Immunol Volume: 170 Page(s): 147 - 152
  01/01/2003 Authors: Hathcock KS; Kaech SM; Ahmed R; Hodes RJ
• Prolonged presence of effector-memory CD8 T cells in the central nervous system after dengue virus encephalitis.
  Int Immunol Volume: 15 Page(s): 119 - 125
  01/01/2003 Authors: van der Most RG; Murali-Krishna K; Ahmed R
• Molecular and functional profiling of memory CD8 T cell differentiation.
  Cell Volume: 111 Page(s): 837 - 851
  12/13/2002 Authors: Kaech SM; Hemby S; Kersh E; Ahmed R
• Cutting edge: persistent viral infection prevents tolerance induction and escapes immune control following CD28/CD40 blockade-based regimen.
  J Immunol Volume: 169 Page(s): 5387 - 5391
  11/15/2002 Authors: Williams MA; Onami TM; Adams AB; Durham MM; Pearson TC; Ahmed R; Larsen CP
• Differential sensitivity of naive and memory CD8+ T cells to apoptosis in vivo.
  J Immunol Volume: 169 Page(s): 3760 - 3770
  10/01/2002 Authors: Grayson JM; Harrington LE; Lanier JG; Wherry EJ; Ahmed R
• Viral and bacterial infections induce expression of multiple NK cell receptors in responding CD8(+) T cells.
  J Immunol Volume: 169 Page(s): 1444 - 1452
  08/01/2002 Authors: McMahon CW; Zajac AJ; Jamieson AM; Corral L; Hammer GE; Ahmed R; Raulet DH
• Interleukin 15 is required for proliferative renewal of virus-specific memory CD8 T cells.
  J Exp Med Volume: 195 Page(s): 1541 - 1548
  06/17/2002 Authors: Becker TC; Wherry EJ; Boone D; Murali-Krishna K; Antia R; Ma A; Ahmed R
• Dynamic regulation of T cell immunity by CD43.
  J Immunol Volume: 168 Page(s): 6022 - 6031
  06/15/2002 Authors: Onami TM; Harrington LE; Williams MA; Galvan M; Larsen CP; Pearson TC; Manjunath N; Baum LG; Pearce BD; Ahmed R
• Defective generation but normal maintenance of memory T cells in old mice.
  Eur J Immunol Volume: 32 Page(s): 1567 - 1573
  06/01/2002 Authors: Kapasi ZF; Murali-Krishna K; McRae ML; Ahmed R
• Yellow fever virus 17D envelope and NS3 proteins are major targets of the antiviral T cell response in mice.
  Virology Volume: 296 Page(s): 117 - 124
  04/25/2002 Authors: van der Most RG; Harrington LE; Giuggio V; Mahar PL; Ahmed R
• Effector and memory T-cell differentiation: implications for vaccine development.
  Nat Rev Immunol Volume: 2 Page(s): 251 - 262
  04/01/2002 Authors: Kaech SM; Wherry EJ; Ahmed R
• Role of lymphotoxin alpha in T-cell responses during an acute viral infection.
  J Virol Volume: 76 Page(s): 3943 - 3951
  04/01/2002 Authors: Suresh M; Lanier G; Large MK; Whitmire JK; Altman JD; Ruddle NH; Ahmed R
• Recombinant vaccinia virus-induced T-cell immunity: quantitation of the response to the virus vector and the foreign epitope.
  J Virol Volume: 76 Page(s): 3329 - 3337
  04/01/2002 Authors: Harrington LE; Most Rv RVD; Whitton JL; Ahmed R
• Estimating the precursor frequency of naive antigen-specific CD8 T cells.
  J Exp Med Volume: 195 Page(s): 657 - 664
  03/04/2002 Authors: Blattman JN; Antia R; Sourdive DJD; Wang X; Kaech SM; Murali-Krishna K; Altman JD; Ahmed R
• Homeostatic proliferation but not the generation of virus specific memory CD8 T cells is impaired in the absence of IL-15 or IL-15Ralpha.
  Adv Exp Med Biol Volume: 512 Page(s): 165 - 175
  01/01/2002 Authors: Wherry EJ; Becker TC; Boone D; Kaja M-K; Ma A; Ahmed R
• Role of CD28-B7 interactions in generation and maintenance of CD8 T cell memory.
  J Immunol Volume: 167 Page(s): 5565 - 5573
  11/15/2001 Authors: Suresh M; Whitmire JK; Harrington LE; Larsen CP; Pearson TC; Altman JD; Ahmed R
• Recruitment times, proliferation, and apoptosis rates during the CD8(+) T-cell response to lymphocytic choriomeningitis virus.
  J Virol Volume: 75 Page(s): 10663 - 10669
  11/01/2001 Authors: De Boer RJ; Oprea M; Antia R; Murali-Krishna K; Ahmed R; Perelson AS
• Characterization of virus-mediated inhibition of mixed chimerism and allospecific tolerance.
  J Immunol Volume: 167 Page(s): 4987 - 4995
  11/01/2001 Authors: Williams MA; Tan JT; Adams AB; Durham MM; Shirasugi N; Whitmire JK; Harrington LE; Ahmed R; Pearson TC; Larsen CP
• Distinct CD8 T cell functions mediate susceptibility to histoplasmosis during chronic viral infection.
  J Immunol Volume: 167 Page(s): 4566 - 4573
  10/15/2001 Authors: Wu-Hsieh BA; Whitmire JK; de Fries R; Lin JS; Matloubian M; Ahmed R
• The role of p53 in regulating antiviral T cell responses.
  J Immunol Volume: 167 Page(s): 1333 - 1337
  08/01/2001 Authors: Grayson JM; Lanier JG; Altman JD; Ahmed R
• The economy of T-cell memory: CD4+ recession in times of CD8+ stability?
  Nat Med Volume: 7 Page(s): 892 - 893
  08/01/2001 Authors: Whitmire JK; Ahmed R
• Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP.
  Proc Natl Acad Sci U S A Volume: 98 Page(s): 7449 - 7454
  06/19/2001 Authors: Czar MJ; Kersh EN; Mijares LA; Lanier G; Lewis J; Yap G; Chen A; Sher A; Duckett CS; Ahmed R
• In vivo selection of a lymphocytic choriomeningitis virus variant that affects recognition of the GP33-43 epitope by H-2Db but not H-2Kb.
  J Virol Volume: 75 Page(s): 5099 - 5107
  06/01/2001 Authors: Puglielli MT; Zajac AJ; van der Most RG; Dzuris JL; Sette A; Altman JD; Ahmed R
• Monocyte-derived human macrophages and peripheral blood mononuclear cells infected with ebola virus secrete MIP-1alpha and TNF-alpha and inhibit poly-IC-induced IFN-alpha in vitro.
  Virology Volume: 284 Page(s): 20 - 25
  05/25/2001 Authors: Gupta M; Mahanty S; Ahmed R; Rollin PE
• Passive transfer of antibodies protects immunocompetent and imunodeficient mice against lethal Ebola virus infection without complete inhibition of viral replication.
  J Virol Volume: 75 Page(s): 4649 - 4654
  05/01/2001 Authors: Gupta M; Mahanty S; Bray M; Ahmed R; Rollin PE
• Memory CD8+ T cell differentiation: initial antigen encounter triggers a developmental program in nave cells.
  Nat Immunol Volume: 2 Page(s): 415 - 422
  05/01/2001 Authors: Kaech SM; Ahmed R
• Role of ligands for lymphotoxin-beta receptor and tumor necrosis factor receptor in T cell activation and effector function
  FASEB JOURNAL Volume: 15 Page(s): A1041 - A1041
  03/08/2001 Authors: Suresh M; Puglielli M; Browning J; Altman JD; Ahmed R
• Dynamic regulation of CD43 on T cells during a viral response.
  FASEB JOURNAL Volume: 15 Page(s): A343 - A343
  03/07/2001 Authors: Onami TM; Harrington LE; Manjunath N; Baum L; Ahmed R
• Cellular immune response in acute infection with Ebola virus
  FASEB JOURNAL Volume: 15 Page(s): A308 - A308
  03/07/2001 Authors: Gupta M; Mahanty S; Ahmed R; Rollin PE
• Interleukin-4 acts at the locus of the antigen-presenting dendritic cell to counter-regulate cytotoxic CD8+ T-cell responses.
  Nat Med Volume: 7 Page(s): 206 - 214
  02/01/2001 Authors: King C; Mueller Hoenger R; Malo Cleary M; Murali-Krishna K; Ahmed R; King E; Sarvetnick N
• Gene expression in antigen-specific CD8+ T cells during viral infection.
  J Immunol Volume: 166 Page(s): 795 - 799
  01/15/2001 Authors: Grayson JM; Murali-Krishna K; Altman JD; Ahmed R
• Analysis of Mitochondrial Function in Antigen Specific na ve, Effector and MEmory CD8 + T Cells.
  ScientificWorldJournal Volume: 1 Page(s): 53
  01/01/2001 Authors: Grayson JM; Lanier JG; Harrington LE; Altman JD; Ahmed R
• Genetic dissection of age-related changes of immune function in mice.
  Scand J Immunol Volume: 54 Page(s): 10 - 20
  01/01/2001 Authors: Mountz JD; Van Zant GE; Zhang HG; Grizzle WE; Ahmed R; Williams RW; Hsu HC
• Evolution of the T cell repertoire during primary, memory, and recall responses to viral infection.
  J Immunol Volume: 165 Page(s): 6081 - 6090
  12/01/2000 Authors: Blattman JN; Sourdive DJ; Murali-Krishna K; Ahmed R; Altman JD
• Chimeric yellow fever/dengue virus as a candidate dengue vaccine: quantitation of the dengue virus-specific CD8 T-cell response.
  J Virol Volume: 74 Page(s): 8094 - 8101
  09/01/2000 Authors: van Der Most RG; Murali-Krishna K; Ahmed R; Strauss JH
• Cutting edge: naive T cells masquerading as memory cells.
  J Immunol Volume: 165 Page(s): 1733 - 1737
  08/15/2000 Authors: Murali-Krishna K; Ahmed R
• Costimulation in antiviral immunity: differential requirements for CD4(+) and CD8(+) T cell responses.
  Curr Opin Immunol Volume: 12 Page(s): 448 - 455
  08/01/2000 Authors: Whitmire JK; Ahmed R
• Virus-specific CD8 T cell silencing: The role of viral load and CD4 T cell help.
  FASEB JOURNAL Volume: 14 Page(s): A978 - A978
  04/20/2000 Authors: Zajac AJ; Lau L; Altman JD; Ahmed R
• Cutting edge: increased expression of Bcl-2 in antigen-specific memory CD8+ T cells.
  J Immunol Volume: 164 Page(s): 3950 - 3954
  04/15/2000 Authors: Grayson JM; Zajac AJ; Altman JD; Ahmed R
• Antiviral CD4 and CD8 T-cell memory: differences in the size of the response and activation requirements.
  Philos Trans R Soc Lond B Biol Sci Volume: 355 Page(s): 373 - 379
  03/29/2000 Authors: Whitmire JK; Murali-Krishna K; Altman J; Ahmed R
• 4-1BB costimulation is required for protective anti-viral immunity after peptide vaccination.
  J Immunol Volume: 164 Page(s): 2320 - 2325
  03/01/2000 Authors: Tan JT; Whitmire JK; Murali-Krishna K; Ahmed R; Altman JD; Mittler RS; Sette A; Pearson TC; Larsen CP
• Immune memory and protective immunity
  Volume: 1205 Page(s): 69 - 73
  01/01/2000 Authors: Ahmed R
• Reversal of virus-induced systemic shock and respiratory failure by blockade of the lymphotoxin pathway.
  Nat Med Volume: 5 Page(s): 1370 - 1374
  12/01/1999 Authors: Puglielli MT; Browning JL; Brewer AW; Schreiber RD; Shieh WJ; Altman JD; Oldstone MB; Zaki SR; Ahmed R
• Impaired anti-viral T cell responses due to expression of the Ly49A inhibitory receptor.
  J Immunol Volume: 163 Page(s): 5526 - 5534
  11/15/1999 Authors: Zajac AJ; Vance RE; Held W; Sourdive DJ; Altman JD; Raulet DH; Ahmed R
• Persistence of memory CD8 T cells in MHC class I-deficient mice.
  Science Volume: 286 Page(s): 1377 - 1381
  11/12/1999 Authors: Murali-Krishna K; Lau LL; Sambhara S; Lemonnier F; Altman J; Ahmed R
• Quantitative measurement of birth and death of immune cell populations in terms of a cell-cycle based model
  MOLECULAR BIOLOGY OF THE CELL Volume: 10 Page(s): 320A - 320A
  11/01/1999 Authors: Anita R; Ganusov V; Pilyugin S; Murali K; Krishna M; Ahmed R
• 4-1BB ligand, a member of the TNF family, is important for the generation of antiviral CD8 T cell responses.
  J Immunol Volume: 163 Page(s): 4859 - 4868
  11/01/1999 Authors: Tan JT; Whitmire JK; Ahmed R; Pearson TC; Larsen CP
• Peptide vaccination using nonionic block copolymers induces protective anti-viral CTL responses.
  Vaccine Volume: 18 Page(s): 549 - 557
  10/14/1999 Authors: Lanier JG; Newman MJ; Lee EM; Sette A; Ahmed R
• CD40-CD40 ligand costimulation is required for generating antiviral CD4 T cell responses but is dispensable for CD8 T cell responses.
  J Immunol Volume: 163 Page(s): 3194 - 3201
  09/15/1999 Authors: Whitmire JK; Flavell RA; Grewal IS; Larsen CP; Pearson TC; Ahmed R
• Cytotoxic T-lymphocyte epitopes fused to anthrax toxin induce protective antiviral immunity.
  Infect Immun Volume: 67 Page(s): 3290 - 3296
  07/01/1999 Authors: Doling AM; Ballard JD; Shen H; Krishna KM; Ahmed R; Collier RJ; Starnbach MN
• Two roads diverged: interferon alpha/beta- and interleukin 12-mediated pathways in promoting T cell interferon gamma responses during viral infection.
  J Exp Med Volume: 189 Page(s): 1315 - 1328
  04/19/1999 Authors: Cousens LP; Peterson R; Hsu S; Dorner A; Altman JD; Ahmed R; Biron CA
• B cell memory and the long-lived plasma cell.
  Curr Opin Immunol Volume: 11 Page(s): 172 - 179
  04/01/1999 Authors: McHeyzer-Williams MG; Ahmed R
• A role for perforin in downregulating T-cell responses during chronic viral infection.
  J Virol Volume: 73 Page(s): 2527 - 2536
  03/01/1999 Authors: Matloubian M; Suresh M; Glass A; Galvan M; Chow K; Whitmire JK; Walsh CM; Clark WR; Ahmed R
• T-cell anergy during chronic viral infection
  Page(s): 243 - 253
  01/01/1999 Authors: Blattman JN; Zajac AJ; Murali-Krishna K; Sourdive DJD; Suresh M; Altman JD; Ahmed R
• Viral immune evasion due to persistence of activated T cells without effector function.
  J Exp Med Volume: 188 Page(s): 2205 - 2213
  12/21/1998 Authors: Zajac AJ; Blattman JN; Murali-Krishna K; Sourdive DJ; Suresh M; Altman JD; Ahmed R
• Models of immune memory: on the role of cross-reactive stimulation, competition, and homeostasis in maintaining immune memory.
  Proc Natl Acad Sci U S A Volume: 95 Page(s): 14926 - 14931
  12/08/1998 Authors: Antia R; Pilyugin SS; Ahmed R
• Long-term CD4 Th1 and Th2 memory following acute lymphocytic choriomeningitis virus infection.
  J Virol Volume: 72 Page(s): 8281 - 8288
  10/01/1998 Authors: Whitmire JK; Asano MS; Murali-Krishna K; Suresh M; Ahmed R
• Divergent IFN-alpha/beta- and IL-12-mediated pathways supporting protective T cell responses to lymphocytic choriomeningitis infections.
  EUROPEAN CYTOKINE NETWORK Volume: 9 Page(s): 350 - 350
  09/01/1998 Authors: Cousens LP; Altman JD; Dorner A; Ahmed R; Biron CA
• Therapeutic vaccination against chronic viral infection: the importance of cooperation between CD4+ and CD8+ T cells.
  Curr Opin Immunol Volume: 10 Page(s): 444 - 449
  08/01/1998 Authors: Zajac AJ; Murali-Krishna K; Blattman JN; Ahmed R
• Immunity to infection.
  Curr Opin Immunol Volume: 10 Page(s): 419 - 421
  08/01/1998 Authors: Bloom B; Ahmed R
• Alterations in cell surface carbohydrates on T cells from virally infected mice can distinguish effector/memory CD8+ T cells from naive cells.
  J Immunol Volume: 161 Page(s): 641 - 648
  07/15/1998 Authors: Galvan M; Murali-Krishna K; Ming LL; Baum L; Ahmed R
• Conserved T cell receptor repertoire in primary and memory CD8 T cell responses to an acute viral infection.
  J Exp Med Volume: 188 Page(s): 71 - 82
  07/06/1998 Authors: Sourdive DJ; Murali-Krishna K; Altman JD; Zajac AJ; Whitmire JK; Pannetier C; Kourilsky P; Evavold B; Sette A; Ahmed R
• Long-lived plasma cells: a mechanism for maintaining persistent antibody production.
  Curr Opin Immunol Volume: 10 Page(s): 252 - 258
  06/01/1998 Authors: Slifka MK; Ahmed R
• Virus-specific CD8+ T cells in primary and secondary influenza pneumonia.
  Immunity Volume: 8 Page(s): 683 - 691
  06/01/1998 Authors: Flynn KJ; Belz GT; Altman JD; Ahmed R; Woodland DL; Doherty PC
• CD4+ and CD8+ T cell interactions in IFN-gamma and IL-4 responses to viral infections: requirements for IL-2.
  J Immunol Volume: 160 Page(s): 5007 - 5017
  05/15/1998 Authors: Su HC; Cousens LP; Fast LD; Slifka MK; Bungiro RD; Ahmed R; Biron CA
• Humoral immunity due to long-lived plasma cells.
  Immunity Volume: 8 Page(s): 363 - 372
  03/01/1998 Authors: Slifka MK; Antia R; Whitmire JK; Ahmed R
• Compartmentalization of bacterial antigens: differential effects on priming of CD8 T cells and protective immunity.
  Cell Volume: 92 Page(s): 535 - 545
  02/20/1998 Authors: Shen H; Miller JF; Fan X; Kolwyck D; Ahmed R; Harty JT
• Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection.
  Immunity Volume: 8 Page(s): 177 - 187
  02/01/1998 Authors: Murali-Krishna K; Altman JD; Suresh M; Sourdive DJ; Zajac AJ; Miller JD; Slansky J; Ahmed R
• Identification of Db- and Kb-restricted subdominant cytotoxic T-cell responses in lymphocytic choriomeningitis virus-infected mice.
  Virology Volume: 240 Page(s): 158 - 167
  01/05/1998 Authors: van der Most RG; Murali-Krishna K; Whitton JL; Oseroff C; Alexander J; Southwood S; Sidney J; Chesnut RW; Sette A; Ahmed R
• B cell responses and immune memory.
  Dev Biol Stand Volume: 95 Page(s): 105 - 115
  01/01/1998 Authors: Slifka MK; Ahmed R
• In vivo dynamics of anti-viral CD8 T cell responses to different epitopes. An evaluation of bystander activation in primary and secondary responses to viral infection.
  Adv Exp Med Biol Volume: 452 Page(s): 123 - 142
  01/01/1998 Authors: Murali-Krishna K; Altman JD; Suresh M; Sourdive D; Zajac A; Ahmed R
• Recombinant Listeria monocytogenes vaccination eliminates papillomavirus-induced tumors and prevents papilloma formation from viral DNA.
  J Virol Volume: 71 Page(s): 8467 - 8474
  11/01/1997 Authors: Jensen ER; Selvakumar R; Shen H; Ahmed R; Wettstein FO; Miller JF
• Alterations in cell surface carbohydrates on T cells from virally infected mice can distinguish effector/memory CD8+ T cells from naive cells
  GLYCOBIOLOGY Volume: 7 Page(s): 140 - 140
  10/01/1997 Authors: Galvan M; Ming L; Baum L; Ahmed R
• Bone marrow contains virus-specific cytotoxic T lymphocytes.
  Blood Volume: 90 Page(s): 2103 - 2108
  09/01/1997 Authors: Slifka MK; Whitmire JK; Ahmed R
• Recombinant Listeria monocytogenes as a live vaccine vehicle and a probe for studying cell-mediated immunity.
  Immunol Rev Volume: 158 Page(s): 147 - 157
  08/01/1997 Authors: Jensen ER; Shen H; Wettstein FO; Ahmed R; Miller JF
• Regression of papillomas induced by cottontail rabbit papillomavirus is associated with infiltration of CD8+ cells and persistence of viral DNA after regression.
  J Virol Volume: 71 Page(s): 5540 - 5548
  07/01/1997 Authors: Selvakumar R; Schmitt A; Iftner T; Ahmed R; Wettstein FO
• Uncovering subdominant cytotoxic T-lymphocyte responses in lymphocytic choriomeningitis virus-infected BALB/c mice.
  J Virol Volume: 71 Page(s): 5110 - 5114
  07/01/1997 Authors: van der Most RG; Concepcion RJ; Oseroff C; Alexander J; Southwood S; Sidney J; Chesnut RW; Ahmed R; Sette A
• Experimental measles. I. Pathogenesis in the normal and the immunized host.
  Virology Volume: 233 Page(s): 74 - 84
  06/23/1997 Authors: McChesney MB; Miller CJ; Rota PA; Zhu YD; Antipa L; Lerche NW; Ahmed R; Bellini WJ
• B cell longevity and immunological memory.
  Trends Microbiol Volume: 5 Page(s): 180 - 181
  05/01/1997 Authors: Michie CA; Lampert IA
• B cell longevity and immunological memory - Response
  TRENDS IN MICROBIOLOGY Volume: 5 Page(s): 180 - 181
  05/01/1997 Authors: Slifka MK; Ahmed R
• Analysis of cytotoxic T cell responses to dominant and subdominant epitopes during acute and chronic lymphocytic choriomeningitis virus infection.
  J Immunol Volume: 157 Page(s): 5543 - 5554
  12/15/1996 Authors: van der Most RG; Sette A; Oseroff C; Alexander J; Murali-Krishna K; Lau LL; Southwood S; Sidney J; Chesnut RW; Matloubian M
• CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection.
  J Virol Volume: 70 Page(s): 8375 - 8381
  12/01/1996 Authors: Whitmire JK; Slifka MK; Grewal IS; Flavell RA; Ahmed R
• Limiting dilution analysis of virus-specific memory B cells by an ELISPOT assay.
  J Immunol Methods Volume: 199 Page(s): 37 - 46
  11/29/1996 Authors: Slifka MK; Ahmed R
• Long-term antibody production is sustained by antibody-secreting cells in the bone marrow following acute viral infection.
  Ann N Y Acad Sci Volume: 797 Page(s): 166 - 176
  10/25/1996 Authors: Slifka MK; Ahmed R
• Long-term humoral immunity against viruses: revisiting the issue of plasma cell longevity.
  Trends Microbiol Volume: 4 Page(s): 394 - 400
  10/01/1996 Authors: Slifka MK; Ahmed R
• A common major histocompatibility complex class II allele HLA-DQB1* 0301 is present in clinical variants of pemphigoid.
  Proc Natl Acad Sci U S A Volume: 93 Page(s): 8569 - 8571
  08/06/1996 Authors: Delgado JC; Turbay D; Yunis EJ; Yunis JJ; Morton ED; Bhol K; Norman R; Alper CA; Good RA; Ahmed R
• Tickling memory T cells.
  Science Volume: 272 Page(s): 1904
  06/28/1996 Authors: Ahmed R
• Antiviral cytotoxic T-cell memory by vaccination with recombinant Listeria monocytogenes.
  J Virol Volume: 70 Page(s): 2902 - 2910
  05/01/1996 Authors: Slifka MK; Shen H; Matloubian M; Jensen ER; Miller JF; Ahmed R
• CD8 T cell memory in B cell-deficient mice.
  J Exp Med Volume: 183 Page(s): 2165 - 2174
  05/01/1996 Authors: Asano MS; Ahmed R
• Immunological memory and protective immunity: understanding their relation.
  Science Volume: 272 Page(s): 54 - 60
  04/05/1996 Authors: Ahmed R; Gray D
• Introduction: Immunity to viruses
  SEMINARS IN VIROLOGY Volume: 7 Page(s): 93 - 93
  04/01/1996 Authors: Ahmed R
• Intestinal intraepithelial lymphocytes respond to systemic lymphocytic choriomeningitis virus infection.
  Cell Immunol Volume: 167 Page(s): 161 - 169
  02/01/1996 Authors: Sydora BC; Jamieson BD; Ahmed R; Kronenberg M
• IMPAIRED RESPONSIVENESS TO GAMMA-INTERFERON OF MACROPHAGES INFECTED WITH LYMPHOCYTIC CHORIOMENINGITIS VIRUS CLONE-13 - SUSCEPTIBILITY TO HISTOPLASMOSIS (VOL 63, PG 1468, 1995)
  INFECTION AND IMMUNITY Volume: 63 Page(s): 3748 - 3748
  09/01/1995 Authors: VILLARETE L; DEFRIES R; KOLHEKAR S; HOWARD D; AHMED R; WUHSIEH B
• Molecular pathways of CTL-mediated cytotoxicity.
  Immunol Rev Volume: 146 Page(s): 33 - 44
  08/01/1995 Authors: Clark WR; Walsh CM; Glass AA; Hayashi F; Matloubian M; Ahmed R
• Persistent infection of mice with Pichinde virus associated with failure to thrive.
  Microb Pathog Volume: 19 Page(s): 73 - 82
  08/01/1995 Authors: Wright KE; Ahmed R; Buchmeier MJ
• Recombinant Listeria monocytogenes as a live vaccine vehicle for the induction of protective anti-viral cell-mediated immunity.
  Proc Natl Acad Sci U S A Volume: 92 Page(s): 3987 - 3991
  04/25/1995 Authors: Shen H; Slifka MK; Matloubian M; Jensen ER; Ahmed R; Miller JF
• Tumor regression is associated with a specific immune response to the E2 protein of cottontail rabbit papillomavirus.
  Virology Volume: 208 Page(s): 298 - 302
  04/01/1995 Authors: Selvakumar R; Ahmed R; Wettstein FO
• Impaired responsiveness to gamma interferon of macrophages infected with lymphocytic choriomeningitis virus clone 13: susceptibility to histoplasmosis.
  Infect Immun Volume: 63 Page(s): 1468 - 1472
  04/01/1995 Authors: Villarete L; de Fries R; Kolhekar S; Howard D; Ahmed R; Wu-Hsieh B
• DNA vaccination against persistent viral infection.
  J Virol Volume: 69 Page(s): 2574 - 2582
  04/01/1995 Authors: Martins LP; Lau LL; Asano MS; Ahmed R
• Bone marrow is a major site of long-term antibody production after acute viral infection.
  J Virol Volume: 69 Page(s): 1895 - 1902
  03/01/1995 Authors: Slifka MK; Matloubian M; Ahmed R
• COSTIMULATORY SIGNALS AND VIRAL IMMUNITY
  JOURNAL OF CELLULAR BIOCHEMISTRY Page(s): 271 - 271
  01/05/1995 Authors: BORRIELLO F; TIVOL EA; FREEMAN GJ; MATLOUBIAN M; AHMED R; SHARPE AH
• IMMUNOLOGICAL MEMORY TO VIRUSES
  JOURNAL OF CELLULAR BIOCHEMISTRY Page(s): 275 - 275
  01/05/1995 Authors: AHMED R
• BONE-MARROW IS A MAJOR SITE OF LONG-TERM ANTIBODY-PRODUCTION AFTER ACUTE VIRAL-INFECTION
  JOURNAL OF CELLULAR BIOCHEMISTRY Page(s): 303 - 303
  01/05/1995 Authors: AHMED R; SLIFKA MK; MATLOUBIAN M
• PROTECTIVE ANTIVIRAL CELL-MEDIATED-IMMUNITY USING RECOMBINANT LISTERIA-MONOCYTOGENES AS A LIVE VACCINE VEHICLE
  JOURNAL OF CELLULAR BIOCHEMISTRY Page(s): 314 - 314
  01/05/1995 Authors: SLIFKA MK; SHEN H; MATLOUBIAN M; JENSEN EJ; MILLER JF; AHMED R
• Immune conflicts in lymphocytic choriomeningitis virus.
  Springer Semin Immunopathol Volume: 17 Page(s): 247 - 259
  01/01/1995 Authors: Asano MS; Ahmed R
• Immunization with nonstructural proteins E1 and E2 of cottontail rabbit papillomavirus stimulates regression of virus-induced papillomas.
  J Virol Volume: 69 Page(s): 602 - 605
  01/01/1995 Authors: Selvakumar R; Borenstein LA; Lin YL; Ahmed R; Wettstein FO
• Cell-mediated cytotoxicity in perforin-less mice.
  Int Rev Immunol Volume: 13 Page(s): 1 - 14
  01/01/1995 Authors: Clark WR; Walsh CM; Glass AA; Huang MT; Ahmed R; Matloubian M
• CD4+ T cells are required to sustain CD8+ cytotoxic T-cell responses during chronic viral infection.
  J Virol Volume: 68 Page(s): 8056 - 8063
  12/01/1994 Authors: Matloubian M; Concepcion RJ; Ahmed R
• Immune function in mice lacking the perforin gene.
  Proc Natl Acad Sci U S A Volume: 91 Page(s): 10854 - 10858
  11/08/1994 Authors: Walsh CM; Matloubian M; Liu CC; Ueda R; Kurahara CG; Christensen JL; Huang MT; Young JD; Ahmed R; Clark WR
• Tissue-mediated selection of viral variants: correlation between glycoprotein mutation and growth in neuronal cells.
  J Virol Volume: 68 Page(s): 7490 - 7496
  11/01/1994 Authors: Villarete L; Somasundaram T; Ahmed R
• Cytotoxic T-cell memory without antigen.
  Nature Volume: 369 Page(s): 648 - 652
  06/23/1994 Authors: Lau LL; Jamieson BD; Somasundaram T; Ahmed R
• T-cell response to cottontail rabbit papillomavirus structural proteins in infected rabbits.
  J Virol Volume: 68 Page(s): 4043 - 4048
  06/01/1994 Authors: Selvakumar R; Borenstein LA; Lin YL; Ahmed R; Wettstein FO
• Molecular determinants of macrophage tropism and viral persistence: importance of single amino acid changes in the polymerase and glycoprotein of lymphocytic choriomeningitis virus.
  J Virol Volume: 67 Page(s): 7340 - 7349
  12/01/1993 Authors: Matloubian M; Kolhekar SR; Somasundaram T; Ahmed R
• Cottontail rabbit papillomavirus L1 protein-based vaccines: protection is achieved only with a full-length, nondenatured product.
  J Virol Volume: 67 Page(s): 4154 - 4162
  07/01/1993 Authors: Lin YL; Borenstein LA; Ahmed R; Wettstein FO
• INVIVO SELECTION OF LYMPHOCYTE-TROPIC AND MACROPHAGE-TROPIC VARIANTS OF LYMPHOCYTIC CHORIOMENINGITIS VIRUS
  JOURNAL OF CELLULAR BIOCHEMISTRY Page(s): 57 - 57
  03/13/1993 Authors: KING CC; MATLOUBIAN M; SOMASUNDARAM T; AHMED R
• CD8+ T-CELL MEDIATED HEMATOPOIETIC DYSFUNCTION IN CHRONIC VIRAL-INFECTION
  JOURNAL OF CELLULAR BIOCHEMISTRY Page(s): 58 - 58
  03/13/1993 Authors: MATLOUBIAN M; LAU L; KING CC; WUHSIEH B; AHMED R
• SELECTION OF VIRAL VARIANTS IN SCID MICE
  JOURNAL OF CELLULAR BIOCHEMISTRY Page(s): 63 - 63
  03/13/1993 Authors: ASANO MS; SOMASUNDARAM T; MATLOUBIAN M; PHAM P; AHMED R
• POLYCLONAL ACTIVATION OF T-CELLS, APOPTOSIS, AND MEMORY IN VIRAL-INFECTION
  JOURNAL OF CELLULAR BIOCHEMISTRY Page(s): 58 - 58
  03/13/1993 Authors: LAU L; GALVAN M; CONCEPCION R; SOMASUNDARUM T; MATLOUBIAN M; AHMED R
• EFFECTIVE VACCINATION AGAINST PAPILLOMA DEVELOPMENT BY IMMUNIZATION WITH L1 OR L2 STRUCTURAL PROTEIN OF COTTONTAIL RABBIT PAPILLOMAVIRUS
  JOURNAL OF CELLULAR BIOCHEMISTRY Page(s): 87 - 87
  03/13/1993 Authors: LIU YI; BORENSTEIN LA; SELVAKUMA R; AHMED R; WETTSTEIN FO
• Progression from papilloma to carcinoma is accompanied by changes in antibody response to papillomavirus proteins.
  J Virol Volume: 67 Page(s): 382 - 389
  01/01/1993 Authors: Lin YL; Borenstein LA; Selvakumar R; Ahmed R; Wettstein FO
• Viral infection of the thymus.
  J Virol Volume: 66 Page(s): 3155 - 3160
  05/01/1992 Authors: King CC; Jamieson BD; Reddy K; Bali N; Concepcion RJ; Ahmed R
• Immunological memory against viruses.
  Semin Immunol Volume: 4 Page(s): 105 - 109
  04/01/1992 Authors: Ahmed R
• Effective vaccination against papilloma development by immunization with L1 or L2 structural protein of cottontail rabbit papillomavirus.
  Virology Volume: 187 Page(s): 612 - 619
  04/01/1992 Authors: Lin YL; Borenstein LA; Selvakumar R; Ahmed R; Wettstein FO
• CD8+ T-CELL MEMORY PERSISTS WITHOUT ANTIGEN
  FASEB JOURNAL Volume: 6 Page(s): A1974 - A1974
  02/28/1992 Authors: LAU L; JAMIESON BD; SOMUSUNDARUM T; AHMED R
• IMPAIRED MACROPHAGE ACTIVATION IN VIRAL-INDUCED IMMUNE SUPPRESSION
  FASEB JOURNAL Volume: 6 Page(s): A1999 - A1999
  02/28/1992 Authors: VILLARETE LH; WUHSIEH B; HOWARD DH; AHMED R
• ABROGATION OF TOLERANCE TO A CHRONIC VIRAL-INFECTION
  FASEB JOURNAL Volume: 6 Page(s): A1407 - A1407
  02/26/1992 Authors: JAMIESON BD; SOMASUNDARAM T; AHMED R
• Role of viral strains and host genes in determining levels of immune complexes in a model system: implications for HIV infection.
  AIDS Res Hum Retroviruses Volume: 7 Page(s): 963 - 969
  12/01/1991 Authors: Tishon A; Salmi A; Ahmed R; Oldstone MB
• Abrogation of tolerance to a chronic viral infection.
  J Immunol Volume: 147 Page(s): 3521 - 3529
  11/15/1991 Authors: Jamieson BD; Somasundaram T; Ahmed R
• T-cell tolerance to viruses.
  Curr Opin Immunol Volume: 3 Page(s): 476 - 479
  08/01/1991 Authors: Ahmed R
• Molecular basis of organ-specific selection of viral variants during chronic infection.
  J Virol Volume: 65 Page(s): 4242 - 4247
  08/01/1991 Authors: Ahmed R; Hahn CS; Somasundaram T; Villarete L; Matloubian M; Strauss JH
• CLEARANCE OF MICROBIAL INFECTION
  AIDS RESEARCH AND HUMAN RETROVIRUSES Volume: 6 Page(s): 1350 - 1350
  11/01/1990 Authors: AHMED R
• In vivo selection of lymphocyte-tropic and macrophage-tropic variants of lymphocytic choriomeningitis virus during persistent infection.
  J Virol Volume: 64 Page(s): 5611 - 5616
  11/01/1990 Authors: King CC; de Fries R; Kolhekar SR; Ahmed R
• Genetic basis of viral persistence: single amino acid change in the viral glycoprotein affects ability of lymphocytic choriomeningitis virus to persist in adult mice.
  J Exp Med Volume: 172 Page(s): 1043 - 1048
  10/01/1990 Authors: Matloubian M; Somasundaram T; Kolhekar SR; Selvakumar R; Ahmed R
• Viruses as therapeutic agents. II. Viral reassortants map prevention of insulin-dependent diabetes mellitus to the small RNA of lymphocytic choriomeningitis virus.
  J Exp Med Volume: 171 Page(s): 2091 - 2100
  06/01/1990 Authors: Oldstone MB; Ahmed R; Salvato M
• T cell memory. Long-term persistence of virus-specific cytotoxic T cells.
  J Exp Med Volume: 169 Page(s): 1993 - 2005
  06/01/1989 Authors: Jamieson BD; Ahmed R
• Genetic analysis of in vivo-selected viral variants causing chronic infection: importance of mutation in the L RNA segment of lymphocytic choriomeningitis virus.
  J Virol Volume: 62 Page(s): 3301 - 3308
  09/01/1988 Authors: Ahmed R; Simon RS; Matloubian M; Kolhekar SR; Southern PJ; Freedman DM
• Virus-induced immunosuppression: a murine model of susceptibility to opportunistic infection.
  J Infect Dis Volume: 158 Page(s): 232 - 235
  07/01/1988 Authors: Wu-Hsieh B; Howard DH; Ahmed R
• T4+ T helper cell function in vivo: differential requirement for induction of antiviral cytotoxic T-cell and antibody responses.
  J Virol Volume: 62 Page(s): 2102 - 2106
  06/01/1988 Authors: Ahmed R; Butler LD; Bhatti L
• Organ-specific selection of viral variants during chronic infection.
  J Exp Med Volume: 167 Page(s): 1719 - 1724
  05/01/1988 Authors: Ahmed R; Oldstone MB
• T-cell tolerance: exposure to virus in utero does not cause a permanent deletion of specific T cells.
  Proc Natl Acad Sci U S A Volume: 85 Page(s): 2265 - 2268
  04/01/1988 Authors: Jamieson BD; Ahmed R
• Immune therapy of a persistent and disseminated viral infection.
  J Virol Volume: 61 Page(s): 3920 - 3929
  12/01/1987 Authors: Ahmed R; Jamieson BD; Porter DD
• Effective clearance of a persistent viral infection requires cooperation between virus-specific Lyt2+ T cells and nonspecific bone marrow-derived cells.
  J Virol Volume: 61 Page(s): 3930 - 3937
  12/01/1987 Authors: Jamieson BD; Butler LD; Ahmed R
• Virus-lymphocyte interaction: T cells of the helper subset are infected with lymphocytic choriomeningitis virus during persistent infection in vivo.
  J Virol Volume: 61 Page(s): 1571 - 1576
  05/01/1987 Authors: Ahmed R; King CC; Oldstone MB
• Phage-typing scheme for Escherichia coli O157:H7.
  J Infect Dis Volume: 155 Page(s): 806 - 809
  04/01/1987 Authors: Ahmed R; Bopp C; Borczyk A; Kasatiya S
• Dissecting the molecular anatomy of persistent infection with lymphocytic choriomeningitis virus.
  Med Microbiol Immunol Volume: 175 Page(s): 97 - 99
  01/01/1986 Authors: Valsamakis V; Southern P; Blount P; Ahmed R; Buchmeier MJ; Oldstone MB
• Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus. V. Recognition is restricted to gene products encoded by the viral S RNA segment.
  J Immunol Volume: 136 Page(s): 304 - 307
  01/01/1986 Authors: Riviere Y; Southern PJ; Ahmed R; Oldstone MB
• The use of lymphocytic choriomeningitis virus reassortants to map viral genes causing virulence.
  Med Microbiol Immunol Volume: 175 Page(s): 191 - 192
  01/01/1986 Authors: Riviere Y; Ahmed R; Oldstone MB
• Genetic mapping of lymphocytic choriomeningitis virus pathogenicity: virulence in guinea pigs is associated with the L RNA segment.
  J Virol Volume: 55 Page(s): 704 - 709
  09/01/1985 Authors: Riviere Y; Ahmed R; Southern PJ; Buchmeier MJ; Oldstone MB
• Perturbation of differentiated functions during viral infection in vivo. II. Viral reassortants map growth hormone defect to the S RNA of the lymphocytic choriomeningitis virus genome.
  Virology Volume: 142 Page(s): 175 - 182
  04/15/1985 Authors: Riviere Y; Ahmed R; Southern P; Oldstone MB
• Perturbation of differentiated functions during viral infection in vivo. I. Relationship of lymphocytic choriomeningitis virus and host strains to growth hormone deficiency.
  Virology Volume: 142 Page(s): 158 - 174
  04/15/1985 Authors: Oldstone MB; Ahmed R; Buchmeier MJ; Blount P; Tishon A
• The S RNA segment of lymphocytic choriomeningitis virus codes for the nucleoprotein and glycoproteins 1 and 2.
  J Virol Volume: 53 Page(s): 966 - 968
  03/01/1985 Authors: Riviere Y; Ahmed R; Southern PJ; Buchmeier MJ; Dutko FJ; Oldstone MB
• Virus and immune responses: lymphocytic choriomeningitis virus as a prototype model of viral pathogenesis.
  Br Med Bull Volume: 41 Page(s): 70 - 74
  01/01/1985 Authors: Oldstone MB; Ahmed R; Byrne J; Buchmeier MJ; Riviere Y; Southern P
• Selection of genetic variants of lymphocytic choriomeningitis virus in spleens of persistently infected mice. Role in suppression of cytotoxic T lymphocyte response and viral persistence.
  J Exp Med Volume: 160 Page(s): 521 - 540
  08/01/1984 Authors: Ahmed R; Salmi A; Butler LD; Chiller JM; Oldstone MB
• Biology of cloned cytotoxic T lymphocytes specific for lymphocytic choriomeningitis virus. I. Generation and recognition of virus strains and H-2b mutants.
  J Immunol Volume: 133 Page(s): 433 - 439
  07/01/1984 Authors: Byrne JA; Ahmed R; Oldstone MB
• Virus specificity of cytotoxic T lymphocytes generated during acute lymphocytic choriomeningitis virus infection: role of the H-2 region in determining cross-reactivity for different lymphocytic choriomeningitis virus strains.
  J Virol Volume: 51 Page(s): 34 - 41
  07/01/1984 Authors: Ahmed R; Byrne JA; Oldstone MB
• Genetic variation during persistent reovirus infection: isolation of cold-sensitive and temperature-sensitive mutants from persistently infected L cells.
  Virology Volume: 131 Page(s): 71 - 78
  11/01/1983 Authors: Ahmed R; Kauffman RS; Fields BN
• Selection of a mutant S1 gene during reovirus persistent infection of L cells: role in maintenance of the persistent state.
  Virology Volume: 131 Page(s): 79 - 87
  11/01/1983 Authors: Kauffman RS; Ahmed R; Fields BN
• A genetic map of reovirus: assignment of the newly defined mutant groups H, I, and J to genome segments.
  Virology Volume: 125 Page(s): 299 - 313
  03/01/1983 Authors: Ramig RF; Ahmed R; Fields BN
• CYTO-TOXIC LYMPHOCYTE-T CLONES INDUCED BY LYMPHOCYTIC CHORIOMENINGITIS VIRUS - REACTIVITY FOR LCMV STRAINS AND MHC ANTIGENS
  FEDERATION PROCEEDINGS Volume: 42 Page(s): 1373 - 1373
  01/01/1983 Authors: BYRNE J; AHMED R; CASALI P; OLDSTONE MBA
• Role of the S4 gene in the establishment of persistent reovirus infection in L cells.
  Cell Volume: 28 Page(s): 605 - 612
  03/01/1982 Authors: Ahmed R; Fields BN
• Role of the host cell in persistent viral infection: coevolution of L cells and reovoirus during persistent infection.
  Cell Volume: 25 Page(s): 325 - 332
  08/01/1981 Authors: Ahmed R; Canning WM; Kauffman RS; Sharpe AH; Hallum JV; Fields BN
• Reassortment of genome segments between reovirus defective interfering particles and infectious virus: construction of temperature-sensitive and attenuated viruses by rescue of mutations from DI particles.
  Virology Volume: 111 Page(s): 351 - 363
  06/01/1981 Authors: Ahmed R; Fields BN
• Genetic variation during persistent reovirus infection: presence of extragenically suppressed temperature-sensitive lesions in wild-type virus isolated from persistently infected L cells.
  J Virol Volume: 34 Page(s): 383 - 389
  05/01/1980 Authors: Ahmed R; Chakraborty PR; Graham AF; Ramig RF; Fields BN
• Genetic variation during lytic reovirus infection: high-passage stocks of wild-type reovirus contain temperature-sensitive mutants.
  J Virol Volume: 34 Page(s): 285 - 287
  04/01/1980 Authors: Ahmed R; Chakraborty PR; Fields BN
• Genetics of reovirus: the relationship of interference to complementation and reassortment of temperature-sensitive mutants at nonpermissive temperature.
  Virology Volume: 94 Page(s): 119 - 127
  04/15/1979 Authors: Chakraborty PR; Ahmed R; Fields BN
• CHRONIC GRAFT VERSUS HOST-DISEASE - NEW IMMUNODEFICIENCY SYNDROME
  CLINICAL RESEARCH Volume: 26 Page(s): A376 - A376
  01/01/1978 Authors: GALE RP; GRAZE PR; HO W; GOSSETT T; AHMED R; CLINE MJ
• CD40L adjuvant for DNA/MVA vaccine: enhanced protection from acquisition of neutralization sensitive & neutralization resistant mucosal SIV infections
  
  Authors: Kwa S; Sadagopal S; Hong J; Gangadhara S; Basu R; Lai L; Iyer S; Araki K; Earl PL; Wyatt L