Publications

• Access to antibiotics for pneumonia and sepsis in LMICs.
  Lancet Glob Health Volume: 12 Page(s): e1928 - e1929
  12/01/2024 Authors: Ginsburg AS; Duncan K; Klugman KP; Srikantiah P
• Long-term effect of pneumococcal conjugate vaccines on invasive pneumococcal disease incidence among people of all ages from national, active, laboratory-based surveillance in South Africa, 2005-19: a cohort observational study.
  Lancet Glob Health Volume: 12 Page(s): e1470 - e1484
  09/01/2024 Authors: von Gottberg A; Kleynhans J; de Gouveia L; Tempia S; Meiring S; Quan V; du Plessis M; von Mollendorf C; Crowther-Gibson P; Avenant T
• Geographical migration and fitness dynamics of Streptococcus pneumoniae.
  Nature Volume: 631 Page(s): 386 - 392
  07/01/2024 Authors: Belman S; Lefrancq N; Nzenze S; Downs S; du Plessis M; Lo SW; Global Pneumococcal Sequencing Consortium; McGee L; Madhi SA; von Gottberg A
• Association between nasopharyngeal colonization with multiple pneumococcal serotypes and total pneumococcal colonization density in young Peruvian children.
  Int J Infect Dis Volume: 134 Page(s): 248 - 255
  09/01/2023 Authors: Howard LM; Huang X; Chen W; Liu Y; Edwards KM; Griffin MR; Zhu Y; Vidal JE; Klugman KP; Gil AI
• New respiratory syncytial virus immunization products in low- and middle-income countries: potential for cost-effective impact on a high burden of disease in young infants.
  BMC Med Volume: 21 Page(s): 177
  05/15/2023 Authors: Srikantiah P; Klugman KP
• Pneumococcal Carriage and Seroepidemiology Studies to Measure Current and Future Pneumococcal Conjugate Vaccine Effectiveness.
  J Infect Dis Volume: 227 Page(s): 608 - 609
  03/01/2023 Authors: Klugman KP; Rodgers GL
• Respiratory syncytial virus prevention within reach: the vaccine and monoclonal antibody landscape.
  Lancet Infect Dis Volume: 23 Page(s): e2 - e21
  01/01/2023 Authors: Mazur NI; Terstappen J; Baral R; Bardaj A; Beutels P; Buchholz UJ; Cohen C; Crowe JE; Cutland CL; Eckert L
• HLA class I and class II antigens in sarcoidosis.
  S Afr Med J Volume: 112 Page(s): 904 - 910
  12/01/2022 Authors: Morar R; Duarte R; Wadee AA; Feldman C
• Integrated pneumonia surveillance: pandemics and beyond.
  Lancet Glob Health Volume: 10 Page(s): e1709 - e1710
  12/01/2022 Authors: Ginsburg AS; Srikantiah P; Dowell SF; Klugman KP
• Emergence of a multidrug-resistant and virulent Streptococcus pneumoniae lineage mediates serotype replacement after PCV13: an international whole-genome sequencing study.
  Lancet Microbe Volume: 3 Page(s): e735 - e743
  10/01/2022 Authors: Lo SW; Mellor K; Cohen R; Alonso AR; Belman S; Kumar N; Hawkins PA; Gladstone RA; von Gottberg A; Veeraraghavan B
• Key features of pneumococcal isolates recovered in Central and Northwestern Russia in 2011-2018 determined through whole-genome sequencing.
  Microb Genom Volume: 8
  09/01/2022 Authors: Egorova E; Kumar N; Gladstone RA; Urban Y; Voropaeva E; Chaplin AV; Rumiantseva E; Svistunova TS; Hawkins PA; Klugman KP
• Innovative vaccine approaches-a Keystone Symposia report.
  Ann N Y Acad Sci Volume: 1511 Page(s): 59 - 86
  05/01/2022 Authors: Cable J; Rappuoli R; Klemm EJ; Kang G; Mutreja A; Wright GJ; Pizza M; Castro SA; Hoffmann JP; Alter G
• Comparative Genomics of Disease and Carriage Serotype 1 Pneumococci.
  Genome Biol Evol Volume: 14
  04/10/2022 Authors: Chaguza C; Ebruke C; Senghore M; Lo SW; Tientcheu P-E; Gladstone RA; Tonkin-Hill G; Cornick JE; Yang M; Worwui A
• A Streptococcus pneumoniae lineage usually associated with pneumococcal conjugate vaccine (PCV) serotypes is the most common cause of serotype 35B invasive disease in South Africa, following routine use of PCV.
  Microb Genom Volume: 8
  04/01/2022 Authors: Ndlangisa KM; du Plessis M; Lo S; de Gouveia L; Chaguza C; Antonio M; Kwambana-Adams B; Cornick J; Everett DB; Dagan R
• Serotype-specific Cardiac Involvement in Pneumococcal Pneumonia.
  Clin Infect Dis Volume: 74 Page(s): 507 - 508
  02/11/2022 Authors: Klugman KP; Feldman C
• International links between Streptococcus pneumoniae vaccine serotype 4 sequence type (ST) 801 in Northern European shipyard outbreaks of invasive pneumococcal disease.
  Vaccine Volume: 40 Page(s): 1054 - 1060
  02/11/2022 Authors: Gladstone RA; Siira L; Brynildsrud OB; Vestrheim DF; Turner P; Clarke SC; Srifuengfung S; Ford R; Lehmann D; Egorova E
• Widespread sharing of pneumococcal strains in a rural African setting: proximate villages are more likely to share similar strains that are carried at multiple timepoints.
  Microb Genom Volume: 8
  02/01/2022 Authors: Senghore M; Chaguza C; Bojang E; Tientcheu P-E; Bancroft RE; Lo SW; Gladstone RA; McGee L; Worwui A; Foster-Nyarko E
• Impact of Pneumococcal Conjugate Vaccine on Vaccine Serotype-Specific Pneumonia.
  Clin Infect Dis Volume: 73 Page(s): e1434 - e1435
  10/05/2021 Authors: Klugman KP; Rodgers GL
• Genomic surveillance of invasive Streptococcus pneumoniae isolates in the period pre-PCV10 and post-PCV10 introduction in Brazil.
  Microb Genom Volume: 7
  10/01/2021 Authors: Almeida SCG; Lo SW; Hawkins PA; Gladstone RA; Cassiolato AP; Klugman KP; Breiman RF; Bentley SD; McGee L; Brandileone M-CDC
• Triumph of Pneumococcal Conjugate Vaccines: Overcoming a Common Foe.
  J Infect Dis Volume: 224 Page(s): S352 - S359
  09/30/2021 Authors: Rodgers GL; Whitney CG; Klugman KP
• Assessing the Full Burden of Respiratory Syncytial Virus in Young Infants in Low- and Middle-Income Countries: The Importance of Community Mortality Studies.
  Clin Infect Dis Volume: 73 Page(s): S177 - S179
  09/02/2021 Authors: Srikantiah P; Vora P; Klugman KP
• Population genetic structure, serotype distribution and antibiotic resistance of Streptococcus pneumoniae causing invasive disease in children in Argentina.
  Microb Genom Volume: 7
  09/01/2021 Authors: Gagetti P; Lo SW; Hawkins PA; Gladstone RA; Regueira M; Faccone D; Sireva-Argentina Group; Klugman KP; Breiman RF; McGee L
• Streptococcus pneumoniae genomic datasets from an Indian population describing pre-vaccine evolutionary epidemiology using a whole genome sequencing approach.
  Microb Genom Volume: 7
  09/01/2021 Authors: Nagaraj G; Govindan V; Ganaie F; Venkatesha VT; Hawkins PA; Gladstone RA; McGee L; Breiman RF; Bentley SD; Klugman KP
• The role of interspecies recombination in the evolution of antibiotic-resistant pneumococci.
  Elife Volume: 10
  07/14/2021 Authors: D'Aeth JC; van der Linden MP; McGee L; de Lencastre H; Turner P; Song J-H; Lo SW; Gladstone RA; S-Leo R; Ko KS
• Phylogeography and resistome of pneumococcal meningitis in West Africa before and after vaccine introduction.
  Microb Genom Volume: 7
  07/01/2021 Authors: Senghore M; Tientcheu P-E; Worwui AK; Jarju S; Okoi C; Suso SMS; Foster-Nyarko E; Ebruke C; Sonko M; Kourna MH
• Erratum for Geno et al., "Pneumococcal Capsules and Their Types: Past, Present, and Future".
  Clin Microbiol Rev Volume: 34
  03/17/2021 Authors: Geno KA; Gilbert GL; Song JY; Skovsted IC; Klugman KP; Jones C; Konradsen HB; Nahm MH
• Differences in clinical severity of respiratory viral infections in hospitalized children.
  Sci Rep Volume: 11 Page(s): 5163
  03/04/2021 Authors: Althouse BM; Flasche S; Toizumi M; Nguyen H-AT; Vo HM; Le MN; Hashizume M; Ariyoshi K; Anh DD; Rodgers GL
• Direct and indirect effect of 10 valent pneumococcal vaccine on nasopharyngeal carriage in children under 2years of age in Matiari, Pakistan.
  Vaccine Volume: 39 Page(s): 1319 - 1327
  02/22/2021 Authors: Nisar MI; Ahmed S; Jehan F; Shahid S; Shakoor S; Kabir F; Hotwani A; Munir S; Muhammad S; Khalid F
• Pneumococcal Conjugate Vaccine Protection against Coronavirus-Associated Pneumonia Hospitalization in Children Living with and without HIV.
  mBio Volume: 12
  01/08/2021 Authors: Nunes MC; Cutland CL; Klugman KP; Madhi SA
• Time for a third-generation pneumococcal conjugate vaccine.
  Lancet Infect Dis Volume: 21 Page(s): 14 - 16
  01/01/2021 Authors: Klugman KP; Rodgers GL
• COVID-19 pneumonia and the appropriate use of antibiotics.
  Lancet Glob Health Volume: 8 Page(s): e1453 - e1454
  12/01/2020 Authors: Ginsburg AS; Klugman KP
• Leveraging the COVID-19 response to end preventable child deaths from pneumonia.
  Lancet Volume: 396 Page(s): 1709 - 1711
  11/28/2020 Authors: Fore HH; Ghebreyesus TA; Watkins K; Greenslade L; Berkley S; Bassat Q; Duneton P; Klugman K; Golden A
• Bacterial genome-wide association study of hyper-virulent pneumococcal serotype 1 identifies genetic variation associated with neurotropism.
  Commun Biol Volume: 3 Page(s): 559
  10/08/2020 Authors: Chaguza C; Yang M; Cornick JE; du Plessis M; Gladstone RA; Kwambana-Adams BA; Lo SW; Ebruke C; Tonkin-Hill G; Peno C
• Antibiotics for paediatric community-acquired pneumonia in resource-constrained settings.
  Eur Respir J Volume: 56
  09/01/2020 Authors: Ginsburg AS; Klugman KP
• Within-host microevolution of Streptococcus pneumoniae is rapid and adaptive during natural colonisation.
  Nat Commun Volume: 11 Page(s): 3442
  07/10/2020 Authors: Chaguza C; Senghore M; Bojang E; Gladstone RA; Lo SW; Tientcheu P-E; Bancroft RE; Worwui A; Foster-Nyarko E; Ceesay F
• Preparing to introduce new maternal immunizations in low- and lower-middle-income countries: A report from the Bill & Melinda Gates Foundation convening "Allies in Maternal and Newborn Care"; May 3-4, 2018.
  Volume: 38 Page(s): 4355 - 4361
  06/09/2020 Authors: Sobanjo-Ter Meulen A; Liljestrand J; Lawn JE; Hombach J; Smith J; Dickson KE; Munoz FM; Omer SB; Williams BA; Klugman KP
• Efficacy, duration of protection, birth outcomes, and infant growth associated with influenza vaccination in pregnancy: a pooled analysis of three randomised controlled trials.
  Lancet Respir Med Volume: 8 Page(s): 597 - 608
  06/01/2020 Authors: Omer SB; Clark DR; Madhi SA; Tapia MD; Nunes MC; Cutland CL; Simes EAF; Aqil AR; Katz J; Tielsch JM
• Visualizing variation within Global Pneumococcal Sequence Clusters (GPSCs) and country population snapshots to contextualize pneumococcal isolates.
  Microb Genom Volume: 6
  05/01/2020 Authors: Gladstone RA; Lo SW; Goater R; Yeats C; Taylor B; Hadfield J; Lees JA; Croucher NJ; van Tonder AJ; Bentley LJ
• A mosaic tetracycline resistance gene tet(S/M) detected in an MDR pneumococcal CC230 lineage that underwent capsular switching in South Africa.
  J Antimicrob Chemother Volume: 75 Page(s): 512 - 520
  03/01/2020 Authors: Lo SW; Gladstone RA; van Tonder AJ; Du Plessis M; Cornick JE; Hawkins PA; Madhi SA; Nzenze SA; Kandasamy R; Ravikumar KL
• Immunogenicity and safety of different dosing schedules of trivalent inactivated influenza vaccine in pregnant women with HIV: a randomised controlled trial.
  Lancet HIV Volume: 7 Page(s): e91 - e103
  02/01/2020 Authors: Nunes MC; Cutland CL; Moultrie A; Jones S; Ortiz JR; Neuzil KM; Klugman KP; Simes EAF; Weinberg A; Madhi SA
• Epidemiology of invasive bacterial infections in pneumococcal conjugate vaccine-vaccinated and -unvaccinated children under 5 years of age in Soweto, South Africa: a cohort study from a high-HIV burden setting.
  Paediatr Int Child Health Volume: 40 Page(s): 50 - 57
  02/01/2020 Authors: Johnstone SL; Moore DP; Klugman KP; Madhi SA; Groome MJ
• Carriage Dynamics of Pneumococcal Serotypes in Naturally Colonized Infants in a Rural African Setting During the First Year of Life.
  Front Pediatr Volume: 8 Page(s): 587730
  01/01/2020 Authors: Chaguza C; Senghore M; Bojang E; Lo SW; Ebruke C; Gladstone RA; Tientcheu P-E; Bancroft RE; Worwui A; Foster-Nyarko E
• Association of Laboratory Methods, Colonization Density, and Age With Detection of Streptococcus pneumoniae in the Nasopharynx.
  Am J Epidemiol Volume: 188 Page(s): 2110 - 2119
  12/31/2019 Authors: Sutcliffe CG; Grant LR; Cloessner E; Klugman KP; Vidal JE; Reid R; Colelay J; Weatherholtz RC; Chochua S; Jacobs MR
• Nasopharyngeal Pneumococcal Density during Asymptomatic Respiratory Virus Infection and Risk for Subsequent Acute Respiratory Illness.
  Emerg Infect Dis Volume: 25 Page(s): 2040 - 2047
  11/01/2019 Authors: Howard LM; Zhu Y; Griffin MR; Edwards KM; Williams JV; Gil AI; Vidal JE; Klugman KP; Lanata CF; Grijalva CG
• Eliminating Meningococcal Epidemics From the African Meningitis Belt: The Case for Advanced Prevention and Control Using Next-Generation Meningococcal Conjugate Vaccines.
  J Infect Dis Volume: 220 Page(s): S274 - S278
  10/31/2019 Authors: Alderson MR; LaForce FM; Sobanjo-Ter Meulen A; Hwang A; Preziosi M-P; Klugman KP
• Trivalent influenza vaccination randomized control trial of pregnant women and adverse fetal outcomes.
  Vaccine Volume: 37 Page(s): 5397 - 5403
  08/23/2019 Authors: Simes EAF; Nunes MC; Carosone-Link P; Madimabe R; Ortiz JR; Neuzil KM; Klugman KP; Cutland CL; Madhi SA; Matflu Team
• Declining Incidence of Invasive Meningococcal Disease in South Africa: 2003-2016.
  Clin Infect Dis Volume: 69 Page(s): 495 - 504
  07/18/2019 Authors: Meiring S; Cohen C; de Gouveia L; du Plessis M; Kularatne R; Hoosen A; Lekalakala R; Lengana S; Seetharam S; Naicker P
• Pneumococcal lineages associated with serotype replacement and antibiotic resistance in childhood invasive pneumococcal disease in the post-PCV13 era: an international whole-genome sequencing study.
  Lancet Infect Dis Volume: 19 Page(s): 759 - 769
  07/01/2019 Authors: Lo SW; Gladstone RA; van Tonder AJ; Lees JA; du Plessis M; Benisty R; Givon-Lavi N; Hawkins PA; Cornick JE; Kwambana-Adams B
• Putative novel cps loci in a large global collection of pneumococci.
  Microb Genom Volume: 5
  07/01/2019 Authors: van Tonder AJ; Gladstone RA; Lo SW; Nahm MH; du Plessis M; Cornick J; Kwambana-Adams B; Madhi SA; Hawkins PA; Benisty R
• Population versus individual protection by pneumococcal conjugate vaccination.
  Lancet Volume: 393 Page(s): 2102 - 2104
  05/25/2019 Authors: Klugman KP; Rodgers GL
• Maternal interventions vigilance harmonization in low- and middle-income countries: Stakeholder meeting report; Amsterdam, May 1-2, 2018.
  Vaccine Volume: 37 Page(s): 2643 - 2650
  05/06/2019 Authors: Sobanjo-Ter Meulen A; Munoz FM; Kaslow DC; Klugman KP; Omer SB; Vora P; Stergachis A
• International genomic definition of pneumococcal lineages, to contextualise disease, antibiotic resistance and vaccine impact.
  EBioMedicine Volume: 43 Page(s): 338 - 346
  05/01/2019 Authors: Gladstone RA; Lo SW; Lees JA; Croucher NJ; van Tonder AJ; Corander J; Page AJ; Marttinen P; Bentley LJ; Ochoa TJ
• Global Funders Consortium for Universal Influenza Vaccine Development.
  Vaccine Volume: 37 Page(s): 211 - 213
  01/07/2019 Authors: Bresee JS; McKinlay MA; Abramson J; Klugman KP; Wairagkar N; Global Funders Consortium for Universal Influenza Vaccine Development
• Impact of existing vaccines in reducing antibiotic resistance: Primary and secondary effects.
  Proc Natl Acad Sci U S A Volume: 115 Page(s): 12896 - 12901
  12/18/2018 Authors: Klugman KP; Black S
• The role of bacterial vaccines in the prevention of influenza mortality.
  Lancet Glob Health Volume: 6 Page(s): e1268 - e1269
  12/01/2018 Authors: Klugman KP; Madhi SA; Ginsburg AS; Rodgers GL
• Seasonality of respiratory viruses causing hospitalizations for acute respiratory infections in children in Nha Trang, Vietnam.
  Int J Infect Dis Volume: 75 Page(s): 18 - 25
  10/01/2018 Authors: Althouse BM; Flasche S; Minh LN; Thiem VD; Hashizume M; Ariyoshi K; Anh DD; Rodgers GL; Klugman KP; Hu H
• Global Distribution of Invasive Serotype 35D Streptococcus pneumoniae Isolates following Introduction of 13-Valent Pneumococcal Conjugate Vaccine.
  J Clin Microbiol Volume: 56
  07/01/2018 Authors: Lo SW; Gladstone RA; van Tonder AJ; Hawkins PA; Kwambana-Adams B; Cornick JE; Madhi SA; Nzenze SA; du Plessis M; Kandasamy R
• Usefulness of the Serial Measurement of Vi Antibodies.
  Clin Infect Dis Volume: 67 Page(s): 25 - 26
  06/18/2018 Authors: Klugman KP
• Antibiotic prophylaxis-Preventing severe infections and saving lives in poor countries with very high mortality risk.
  PLoS Med Volume: 15 Page(s): e1002594
  06/01/2018 Authors: Klugman KP; Izadnegahdar R
• A Mechanism of Unidirectional Transformation, Leading to Antibiotic Resistance, Occurs within Nasopharyngeal Pneumococcal Biofilm Consortia.
  mBio Volume: 9
  05/15/2018 Authors: Lattar SM; Wu X; Brophy J; Sakai F; Klugman KP; Vidal JE
• Dynamics of Colonization of Streptococcus pneumoniae Strains in Healthy Peruvian Children.
  Open Forum Infect Dis Volume: 5 Page(s): ofy039
  03/01/2018 Authors: Nelson KN; Grijalva CG; Chochua S; Hawkins PA; Gil AI; Lanata CF; Griffin MR; Edwards KM; Klugman KP; Vidal JE
• Invasive Disease Caused Simultaneously by Dual Serotypes of Streptococcus pneumoniae.
  J Clin Microbiol Volume: 56
  01/01/2018 Authors: Ndlangisa K; du Plessis M; Allam M; Wolter N; de Gouveia L; Klugman KP; Cohen C; Gladstone RA; von Gottberg A
• Vaccination to reduce antimicrobial resistance.
  Lancet Glob Health Volume: 5 Page(s): e1176 - e1177
  12/01/2017 Authors: Ginsburg AS; Klugman KP
• ROLE OF NASOPHARYNGEAL PNEUMOCOCCAL DENSITY IN THE EVOLUTION OF ACUTE RESPIRATORY ILLNESSES IN YOUNG PERUVIAN CHILDREN
  Volume: 95 Page(s): 393 - 394
  11/01/2017 Authors: Fan RR; Howard LM; Griffin MR; Edwards KM; Zhu Y; Williams JV; Vidal JE; Klugman KP; Gil AI; Lanata CF
• Efficacy of Maternal Influenza Vaccination Against All-Cause Lower Respiratory Tract Infection Hospitalizations in Young Infants: Results From a Randomized Controlled Trial.
  Clin Infect Dis Volume: 65 Page(s): 1066 - 1071
  10/01/2017 Authors: Nunes MC; Cutland CL; Jones S; Downs S; Weinberg A; Ortiz JR; Neuzil KM; Simes EAF; Klugman KP; Madhi SA
• Identifying transmission routes of Streptococcus pneumoniae and sources of acquisitions in high transmission communities.
  Epidemiol Infect Volume: 145 Page(s): 2750 - 2758
  10/01/2017 Authors: Althouse BM; Hammitt LL; Grant L; Wagner BG; Reid R; Larzelere-Hinton F; Weatherholtz R; Klugman KP; Rodgers GL; O'Brien KL
• Laboratory-acquired infections of Salmonella enterica serotype Typhi in South Africa: phenotypic and genotypic analysis of isolates.
  BMC Infect Dis Volume: 17 Page(s): 656
  09/29/2017 Authors: Smith AM; Smouse SL; Tau NP; Bamford C; Moodley VM; Jacobs C; McCarthy KM; Lourens A; Keddy KH; GERMS-SA Surveillance Network
• Development and characterization of a synthetic DNA, NUversa, to be used as a standard in quantitative polymerase chain reactions for molecular pneumococcal serotyping.
  FEMS Microbiol Lett Volume: 364
  09/15/2017 Authors: Sakai F; Sonaty G; Watson D; Klugman KP; Vidal JE
• Imputing the Direct and Indirect Effectiveness of Childhood Pneumococcal Conjugate Vaccine Against Invasive Pneumococcal Disease by Surveying Temporal Changes in Nasopharyngeal Pneumococcal Colonization.
  Am J Epidemiol Volume: 186 Page(s): 435 - 444
  08/15/2017 Authors: Nzenze SA; Madhi SA; Shiri T; Klugman KP; de Gouveia L; Moore DP; Karstaedt AS; Tempia S; Nunes MC; von Gottberg A
• Competitive Dominance within Biofilm Consortia Regulates the Relative Distribution of Pneumococcal Nasopharyngeal Density.
  Appl Environ Microbiol Volume: 83
  08/15/2017 Authors: Wu X; Jacobs NT; Bozio C; Palm P; Lattar SM; Hanke CR; Watson DM; Sakai F; Levin BR; Klugman KP
• The future of paediatric pneumococcal conjugate vaccines.
  Lancet Respir Med Volume: 5 Page(s): 605 - 606
  08/01/2017 Authors: Klugman KP; Rodgers GL
• A new paradigm in pneumococcal conjugate vaccination: moving from individual to herd protection.
  Int J Infect Dis Volume: 60 Page(s): 96 - 97
  07/01/2017 Authors: Rodgers GL; Klugman KP
• Global perspectives on maternal immunisation.
  Lancet Infect Dis Volume: 17 Page(s): 685 - 686
  07/01/2017 Authors: Meulen AS-T; Bergquist S; Klugman KP
• Contribution of Serologic Assays in the Evaluation of Influenza Virus Infection Rates and Vaccine Efficacy in Pregnant Women: Report From Randomized Controlled Trials.
  Clin Infect Dis Volume: 64 Page(s): 1773 - 1779
  06/15/2017 Authors: Madhi SA; Nunes MC; Weinberg A; Kuwanda L; Hugo A; Jones S; van Niekerk N; Ortiz JR; Neuzil KM; Klugman KP
• PERCH in Perspective: What Can It Teach Us About Pneumonia Etiology in Children?
  Clin Infect Dis Volume: 64 Page(s): S185 - S187
  06/15/2017 Authors: Klugman KP; Rodgers GL
• Clinical and microbiological features of invasive nontyphoidal Salmonella associated with HIV-infected patients, Gauteng Province, South Africa.
  Medicine (Baltimore) Volume: 96 Page(s): e6448
  03/01/2017 Authors: Keddy KH; Musekiwa A; Sooka A; Karstaedt A; Nana T; Seetharam S; Nchabaleng M; Lekalakala R; Angulo FJ; Klugman KP
• Effectiveness of the 13-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in South African children: a case-control study.
  Lancet Glob Health Volume: 5 Page(s): e359 - e369
  03/01/2017 Authors: Cohen C; von Mollendorf C; de Gouveia L; Lengana S; Meiring S; Quan V; Nguweneza A; Moore DP; Reubenson G; Moshe M
• The global distribution and diversity of protein vaccine candidate antigens in the highly virulent Streptococcus pnuemoniae serotype 1.
  Vaccine Volume: 35 Page(s): 972 - 980
  02/07/2017 Authors: Cornick JE; Tastan Bishop ; Yalcin F; Kiran AM; Kumwenda B; Chaguza C; Govindpershad S; Ousmane S; Senghore M; du Plessis M
• An association between decreasing incidence of invasive non-typhoidal salmonellosis and increased use of antiretroviral therapy, Gauteng Province, South Africa, 2003-2013.
  PLoS One Volume: 12 Page(s): e0173091
  01/01/2017 Authors: Keddy KH; Takuva S; Musekiwa A; Puren AJ; Sooka A; Karstaedt A; Klugman KP; Angulo FJ
• Multiplex Urinary Antigen Detection for 13 Streptococcus pneumoniae Serotypes Improves Diagnosis of Pneumococcal Pneumonia in South African HIV-Infected Adults.
  J Clin Microbiol Volume: 55 Page(s): 302 - 312
  01/01/2017 Authors: Albrich WC; Pride MW; Madhi SA; Callahan J; Adrian PV; French R; van Niekerk N; Sebastian S; Souza V; Telles J-N
• Strain Level Streptococcus Colonization Patterns during the First Year of Life.
  Front Microbiol Volume: 8 Page(s): 1661
  01/01/2017 Authors: Wright MS; McCorrison J; Gomez AM; Beck E; Harkins D; Shankar J; Mounaud S; Segubre-Mercado E; Mojica AMR; Bacay B
• Nasopharyngeal Pneumococcal Density Is Associated With Viral Activity but Not With Use of Improved Stoves Among Young Andean Children.
  Open Forum Infect Dis Volume: 4 Page(s): ofx161
  01/01/2017 Authors: Howard LM; Fan R; Zhu Y; Griffin MR; Edwards KM; Hartinger S; Williams JV; Vidal JE; Klugman KP; Gil AI
• Estimated severe pneumococcal disease cases and deaths before and after pneumococcal conjugate vaccine introduction in children younger than 5 years of age in South Africa.
  PLoS One Volume: 12 Page(s): e0179905
  01/01/2017 Authors: von Mollendorf C; Tempia S; von Gottberg A; Meiring S; Quan V; Feldman C; Cloete J; Madhi SA; O'Brien KL; Klugman KP
• World Pneumonia Day 2016: pulse oximetry and oxygen.
  Lancet Glob Health Volume: 4 Page(s): e893 - e894
  12/01/2016 Authors: Ginsburg AS; Izadnegahdar R; Klugman KP
• Assessing the Evidence for Maternal Pertussis Immunization: A Report From the Bill & Melinda Gates Foundation Symposium on Pertussis Infant Disease Burden in Low- and Lower-Middle-Income Countries.
  Clin Infect Dis Volume: 63 Page(s): S123 - S133
  12/01/2016 Authors: Sobanjo-Ter Meulen A; Duclos P; McIntyre P; Lewis KDC; Van Damme P; O'Brien KL; Klugman KP
• Understanding pneumococcal serotype 1 biology through population genomic analysis.
  BMC Infect Dis Volume: 16 Page(s): 649
  11/08/2016 Authors: Chaguza C; Cornick JE; Harris SR; Andam CP; Bricio-Moreno L; Yang M; Yalcin F; Ousmane S; Govindpersad S; Senghore M
• Nasopharyngeal Pneumococcal Density and Evolution of Acute Respiratory Illnesses in Young Children, Peru, 2009-2011.
  Emerg Infect Dis Volume: 22 Page(s): 1996 - 1999
  11/01/2016 Authors: Fan RR; Howard LM; Griffin MR; Edwards KM; Zhu Y; Williams JV; Vidal JE; Klugman KP; Gil AI; Lanata CF
• Prevalence of maternal colonisation with group B streptococcus: a systematic review and meta-analysis.
  Lancet Infect Dis Volume: 16 Page(s): 1076 - 1084
  09/01/2016 Authors: Kwatra G; Cunnington MC; Merrall E; Adrian PV; Ip M; Klugman KP; Tam WH; Madhi SA
• Two cases of serotypeable and non-serotypeable variants of Streptococcus pneumoniae detected simultaneously during invasive disease.
  BMC Microbiol Volume: 16 Page(s): 126
  06/24/2016 Authors: Ndlangisa KM; du Plessis M; Allam M; Wolter N; Mohale T; de Gouveia L; Birkhead M; Klugman KP; von Gottberg A
• Nasopharyngeal Pneumococcal Serotypes Before and After Mass Azithromycin Distributions for Trachoma.
  J Pediatric Infect Dis Soc Volume: 5 Page(s): 222 - 226
  06/01/2016 Authors: Keenan JD; Sahlu I; McGee L; Cevallos V; Vidal JE; Chochua S; Hawkins P; Gebre T; Tadesse Z; Emerson PM
• Phylogenetic Analysis of Invasive Serotype 1 Pneumococcus in South Africa, 1989 to 2013.
  J Clin Microbiol Volume: 54 Page(s): 1326 - 1334
  05/01/2016 Authors: du Plessis M; Allam M; Tempia S; Wolter N; de Gouveia L; von Mollendorf C; Jolley KA; Mbelle N; Wadula J; Cornick JE
• Bacterial Density, Serotype Distribution and Antibiotic Resistance of Pneumococcal Strains from the Nasopharynx of Peruvian Children Before and After Pneumococcal Conjugate Vaccine 7.
  Pediatr Infect Dis J Volume: 35 Page(s): 432 - 439
  04/01/2016 Authors: Hanke CR; Grijalva CG; Chochua S; Pletz MW; Hornberg C; Edwards KM; Griffin MR; Verastegui H; Gil AI; Lanata CF
• Epidemiology of Serotype 1 Invasive Pneumococcal Disease, South Africa, 2003-2013.
  Emerg Infect Dis Volume: 22 Page(s): 261 - 270
  02/01/2016 Authors: von Mollendorf C; Cohen C; Tempia S; Meiring S; de Gouveia L; Quan V; Lengana S; Karstaedt A; Dawood H; Seetharam S
• Access to effective antimicrobials: a worldwide challenge.
  Lancet Volume: 387 Page(s): 168 - 175
  01/09/2016 Authors: Laxminarayan R; Matsoso P; Pant S; Brower C; Rttingen J-A; Klugman K; Davies S
• Increased Nasopharyngeal Density and Concurrent Carriage of Streptococcus pneumoniae, Haemophilus influenzae, and Moraxella catarrhalis Are Associated with Pneumonia in Febrile Children.
  PLoS One Volume: 11 Page(s): e0167725
  01/01/2016 Authors: Chochua S; D'Acremont V; Hanke C; Alfa D; Shak J; Kilowoko M; Kyungu E; Kaiser L; Genton B; Klugman KP
• HIV Infection and the Epidemiology of Invasive Pneumococcal Disease (IPD) in South African Adults and Older Children Prior to the Introduction of a Pneumococcal Conjugate Vaccine (PCV).
  PLoS One Volume: 11 Page(s): e0149104
  01/01/2016 Authors: Meiring S; Cohen C; Quan V; de Gouveia L; Feldman C; Karstaedt A; Klugman KP; Madhi SA; Rabie H; Sriruttan C
• The Relevance of a Novel Quantitative Assay to Detect up to 40 Major Streptococcus pneumoniae Serotypes Directly in Clinical Nasopharyngeal and Blood Specimens.
  PLoS One Volume: 11 Page(s): e0151428
  01/01/2016 Authors: Messaoudi M; Milenkov M; Albrich WC; van der Linden MPG; Bnet T; Chou M; Sylla M; Barreto Costa P; Richard N; Klugman KP
• Typhoid Fever in South Africa in an Endemic HIV Setting.
  PLoS One Volume: 11 Page(s): e0164939
  01/01/2016 Authors: Keddy KH; Sooka A; Smith AM; Musekiwa A; Tau NP; Klugman KP; Angulo FJ; GERMS-SA
• Surveillance of the impact of pneumococcal conjugate vaccines in developing countries.
  Hum Vaccin Immunother Volume: 12 Page(s): 417 - 420
  01/01/2016 Authors: Rodgers GL; Klugman KP
• Putting flu on the agenda: New voices, new partners.
  Vaccine Volume: 33 Page(s): 7041 - 7043
  12/08/2015 Authors: Russell C; Klugman K; Van Ranst M; Jacinto I; Laurinaitis E
• Undernutrition and pneumonia mortality.
  Lancet Glob Health Volume: 3 Page(s): e735 - e736
  12/01/2015 Authors: Ginsburg AS; Izadnegahdar R; Berkley JA; Walson JL; Rollins N; Klugman KP
• Path to impact: A report from the Bill and Melinda Gates Foundation convening on maternal immunization in resource-limited settings; Berlin - January 29-30, 2015.
  Vaccine Volume: 33 Page(s): 6388 - 6395
  11/25/2015 Authors: Sobanjo-Ter Meulen A; Abramson J; Mason E; Rees H; Schwalbe N; Bergquist S; Klugman KP
• Clinical and Microbiological Features of Salmonella Meningitis in a South African Population, 2003-2013.
  Clin Infect Dis Volume: 61 Suppl 4 Page(s): S272 - S282
  11/01/2015 Authors: Keddy KH; Sooka A; Musekiwa A; Smith AM; Ismail H; Tau NP; Crowther-Gibson P; Angulo FJ; Klugman KP; Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa (GERMS-SA)
• The PneuCarriage Project: A Multi-Centre Comparative Study to Identify the Best Serotyping Methods for Examining Pneumococcal Carriage in Vaccine Evaluation Studies.
  PLoS Med Volume: 12 Page(s): e1001903
  11/01/2015 Authors: Satzke C; Dunne EM; Porter BD; Klugman KP; Mulholland EK; PneuCarriage project group
• Disease mapping for informing targeted health interventions: childhood pneumonia in Bohol, Philippines.
  Trop Med Int Health Volume: 20 Page(s): 1525 - 1533
  11/01/2015 Authors: Thomas DSK; Anthamatten P; Root ED; Lucero M; Nohynek H; Tallo V; Williams GM; Simes EAF; ARIVAC Consortium
• IMPACT OF PCV7 ON NASOPHARYNGEAL DENSITY, SEROTYPE DISTRIBUTION AND ANTIBIOTIC RESISTANCE OF PNEUMOCOCCAL STRAINS ISOLATED FROM PERUVIAN CHILDREN
  Volume: 93 Page(s): 542 - 542
  10/01/2015 Authors: Hanke CR; Grijalva CG; Chochua S; Pletz MW; Hornberg C; Edwards KM; Griffin MR; Verastegui HA; Gil AI; Lanata CF
• Region-specific diversification of the highly virulent serotype 1 Streptococcus pneumoniae.
  Microb Genom Volume: 1 Page(s): e000027
  08/01/2015 Authors: Cornick JE; Chaguza C; Harris SR; Yalcin F; Senghore M; Kiran AM; Govindpershad S; Ousmane S; Plessis MD; Pluschke G
• Three randomized trials of maternal influenza immunization in Mali, Nepal, and South Africa: Methods and expectations.
  Vaccine Volume: 33 Page(s): 3801 - 3812
  07/31/2015 Authors: Omer SB; Richards JL; Madhi SA; Tapia MD; Steinhoff MC; Aqil AR; Wairagkar N; BMGF Supported Maternal Influenza Immunization Trials Investigators Group
• Live attenuated influenza virus increases pneumococcal translocation and persistence within the middle ear.
  J Infect Dis Volume: 212 Page(s): 195 - 201
  07/15/2015 Authors: Mina MJ; Klugman KP; Rosch JW; McCullers JA
• Pneumococcal Capsules and Their Types: Past, Present, and Future.
  Clin Microbiol Rev Volume: 28 Page(s): 871 - 899
  07/01/2015 Authors: Geno KA; Gilbert GL; Song JY; Skovsted IC; Klugman KP; Jones C; Konradsen HB; Nahm MH
• Dynamics of Increasing IFN- Exposure on Murine MH-S Cell-Line Alveolar Macrophage Phagocytosis of Streptococcus pneumoniae.
  J Interferon Cytokine Res Volume: 35 Page(s): 474 - 479
  06/01/2015 Authors: Mina MJ; Brown LAS; Klugman KP
• Longitudinal study on Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus nasopharyngeal colonization in HIV-infected and -uninfected infants vaccinated with pneumococcal conjugate vaccine.
  Vaccine Volume: 33 Page(s): 2662 - 2669
  05/28/2015 Authors: Madhi SA; Izu A; Nunes MC; Violari A; Cotton MF; Jean-Philippe P; Klugman KP; von Gottberg A; van Niekerk N; Adrian PV
• Increased risk for and mortality from invasive pneumococcal disease in HIV-exposed but uninfected infants aged <1 year in South Africa, 2009-2013.
  Clin Infect Dis Volume: 60 Page(s): 1346 - 1356
  05/01/2015 Authors: von Mollendorf C; von Gottberg A; Tempia S; Meiring S; de Gouveia L; Quan V; Lengana S; Avenant T; du Plessis N; Eley B
• Evidence for clonal expansion after antibiotic selection pressure: pneumococcal multilocus sequence types before and after mass azithromycin treatments.
  J Infect Dis Volume: 211 Page(s): 988 - 994
  03/15/2015 Authors: Keenan JD; Klugman KP; McGee L; Vidal JE; Chochua S; Hawkins P; Cevallos V; Gebre T; Tadesse Z; Emerson PM
• Association between respiratory syncytial virus activity and pneumococcal disease in infants: a time series analysis of US hospitalization data.
  PLoS Med Volume: 12 Page(s): e1001776
  01/01/2015 Authors: Weinberger DM; Klugman KP; Steiner CA; Simonsen L; Viboud C
• Impact of the Hajj on pneumococcal transmission.
  Clin Microbiol Infect Volume: 21 Page(s): 77.e11 - 77.e18
  01/01/2015 Authors: Memish ZA; Assiri A; Almasri M; Alhakeem RF; Turkestani A; Al Rabeeah AA; Akkad N; Yezli S; Klugman KP; O'Brien KL
• Single-plex quantitative assays for the detection and quantification of most pneumococcal serotypes.
  PLoS One Volume: 10 Page(s): e0121064
  01/01/2015 Authors: Sakai F; Chochua S; Satzke C; Dunne EM; Mulholland K; Klugman KP; Vidal JE
• World alliance against antibiotic resistance: The WAAAR declaration against antibiotic resistance.
  Med Intensiva Volume: 39 Page(s): 34 - 39
  01/01/2015 Authors: Carlet J; members of the WAAAR
• World alliance against antibiotic resistance: The WAAAR declaration against antibiotic resistance.
  Med Intensiva Volume: 39 Page(s): 34 - 39
  01/01/2015 Authors: Carlet J; members of the WAAAR
• Risk factors for invasive pneumococcal disease among children less than 5 years of age in a high HIV prevalence setting, South Africa, 2010 to 2012.
  Pediatr Infect Dis J Volume: 34 Page(s): 27 - 34
  01/01/2015 Authors: von Mollendorf C; Cohen C; de Gouveia L; Naidoo N; Meiring S; Quan V; Lindani S; Moore DP; Reubenson G; Moshe M
• Streptococcus pneumoniae Serotypes and Mortality in Adults and Adolescents in South Africa: Analysis of National Surveillance Data, 2003 - 2008.
  PLoS One Volume: 10 Page(s): e0140185
  01/01/2015 Authors: Cohen C; Naidoo N; Meiring S; de Gouveia L; von Mollendorf C; Walaza S; Naicker P; Madhi SA; Feldman C; Klugman KP
• Influenza Vaccination of Pregnant Women and Protection of Their Infants EDITORIAL COMMENT
  OBSTETRICAL & GYNECOLOGICAL SURVEY Volume: 70
  01/01/2015 Authors: Madhi SA; Cutland CL; Kuwanda L; Weinberg A; Hugo A; Jones S; Adrian PV; van Niekerk N; Treurnicht F; Ortiz JR
• Genomic load from sputum samples and nasopharyngeal swabs for diagnosis of pneumococcal pneumonia in HIV-infected adults.
  J Clin Microbiol Volume: 52 Page(s): 4224 - 4229
  12/01/2014 Authors: Albrich WC; Madhi SA; Adrian PV; Telles J-N; Paranhos-Baccal G; Klugman KP
• Prevention of neonatal pneumonia and sepsis via maternal immunisation.
  Lancet Glob Health Volume: 2 Page(s): e679 - e680
  12/01/2014 Authors: Ginsburg AS; Meulen AS-T; Klugman KP
• Polyomaviruses-associated respiratory infections in HIV-infected and HIV-uninfected children.
  J Clin Virol Volume: 61 Page(s): 571 - 578
  12/01/2014 Authors: Nunes MC; Kuschner Z; Rabede Z; Cutland CL; Madimabe R; Kuwanda L; Klugman KP; Adrian PV; Madhi SA
• High nasopharyngeal pneumococcal density, increased by viral coinfection, is associated with invasive pneumococcal pneumonia.
  J Infect Dis Volume: 210 Page(s): 1649 - 1657
  11/15/2014 Authors: Wolter N; Tempia S; Cohen C; Madhi SA; Venter M; Moyes J; Walaza S; Malope-Kgokong B; Groome M; du Plessis M
• Effects of vaccination on invasive pneumococcal disease in South Africa.
  N Engl J Med Volume: 371 Page(s): 1889 - 1899
  11/13/2014 Authors: von Gottberg A; de Gouveia L; Tempia S; Quan V; Meiring S; von Mollendorf C; Madhi SA; Zell ER; Verani JR; O'Brien KL
• Temporal association of infant immunisation with pneumococcal conjugate vaccine on the ecology of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus nasopharyngeal colonisation in a rural South African community.
  Vaccine Volume: 32 Page(s): 5520 - 5530
  09/22/2014 Authors: Nzenze SA; Shiri T; Nunes MC; Klugman KP; Kahn K; Twine R; de Gouveia L; von Gottberg A; Madhi SA
• Effectiveness of 7-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in HIV-infected and -uninfected children in south africa: a matched case-control study.
  Clin Infect Dis Volume: 59 Page(s): 808 - 818
  09/15/2014 Authors: Cohen C; von Mollendorf C; de Gouveia L; Naidoo N; Meiring S; Quan V; Nokeri V; Fortuin-de Smit M; Malope-Kgokong B; Moore D
• Influenza vaccination of pregnant women and protection of their infants.
  N Engl J Med Volume: 371 Page(s): 918 - 931
  09/04/2014 Authors: Madhi SA; Cutland CL; Kuwanda L; Weinberg A; Hugo A; Jones S; Adrian PV; van Niekerk N; Treurnicht F; Ortiz JR
• The role of influenza in the severity and transmission of respiratory bacterial disease.
  Lancet Respir Med Volume: 2 Page(s): 750 - 763
  09/01/2014 Authors: Mina MJ; Klugman KP
• Estimating the prevalence of coinfection with influenza virus and the atypical bacteria Bordetella pertussis, Chlamydophila pneumoniae, and Mycoplasma pneumoniae.
  Eur J Clin Microbiol Infect Dis Volume: 33 Page(s): 1585 - 1589
  09/01/2014 Authors: Mina MJ; Burke RM; Klugman KP
• Pneumococcal colonisation density: a new marker for disease severity in HIV-infected adults with pneumonia.
  BMJ Open Volume: 4 Page(s): e005953
  08/11/2014 Authors: Albrich WC; Madhi SA; Adrian PV; van Niekerk N; Telles J-N; Ebrahim N; Messaoudi M; Paranhos-Baccal G; Giersdorf S; Vernet G
• Defining the estimated core genome of bacterial populations using a Bayesian decision model.
  PLoS Comput Biol Volume: 10 Page(s): e1003788
  08/01/2014 Authors: van Tonder AJ; Mistry S; Bray JE; Hill DMC; Cody AJ; Farmer CL; Klugman KP; von Gottberg A; Bentley SD; Parkhill J
• Cohort profile: The study of respiratory pathogens in Andean children.
  Int J Epidemiol Volume: 43 Page(s): 1021 - 1030
  08/01/2014 Authors: Grijalva CG; Griffin MR; Edwards KM; Williams JV; Gil AI; Verastegui H; Hartinger SM; Vidal JE; Klugman KP; Lanata CF
• The emergence of bacterial "hopeful monsters".
  mBio Volume: 5 Page(s): e01550 - e01514
  07/29/2014 Authors: Croucher NJ; Klugman KP
• Herd protection induced by pneumococcal conjugate vaccine.
  Lancet Glob Health Volume: 2 Page(s): e365 - e366
  07/01/2014 Authors: Klugman KP
• Variable recombination dynamics during the emergence, transmission and 'disarming' of a multidrug-resistant pneumococcal clone.
  BMC Biol Volume: 12 Page(s): 49
  06/23/2014 Authors: Croucher NJ; Hanage WP; Harris SR; McGee L; van der Linden M; de Lencastre H; S-Leo R; Song J-H; Ko KS; Beall B
• Evidence for soft selective sweeps in the evolution of pneumococcal multidrug resistance and vaccine escape.
  Genome Biol Evol Volume: 6 Page(s): 1589 - 1602
  06/10/2014 Authors: Croucher NJ; Chewapreecha C; Hanage WP; Harris SR; McGee L; van der Linden M; Song J-H; Ko KS; de Lencastre H; Turner C
• Factors associated with ceftriaxone nonsusceptibility of Streptococcus pneumoniae: analysis of South African national surveillance data, 2003 to 2010.
  Antimicrob Agents Chemother Volume: 58 Page(s): 3293 - 3305
  06/01/2014 Authors: von Mollendorf C; Cohen C; de Gouveia L; Quan V; Meiring S; Feldman C; Klugman KP; von Gottberg A
• Reply to "no clinical association of live attenuated influenza vaccine with nasal carriage of bacteria or acute otitis media": specific recommendations for future studies.
  mBio Volume: 5 Page(s): e01173 - e01114
  05/13/2014 Authors: Mina MJ; Klugman KP
• Effect of 13-valent pneumococcal conjugate vaccine on admissions to hospital 2 years after its introduction in the USA: a time series analysis.
  Lancet Respir Med Volume: 2 Page(s): 387 - 394
  05/01/2014 Authors: Simonsen L; Taylor RJ; Schuck-Paim C; Lustig R; Haber M; Klugman KP
• The role of influenza and parainfluenza infections in nasopharyngeal pneumococcal acquisition among young children.
  Clin Infect Dis Volume: 58 Page(s): 1369 - 1376
  05/01/2014 Authors: Grijalva CG; Griffin MR; Edwards KM; Williams JV; Gil AI; Verastegui H; Hartinger SM; Vidal JE; Klugman KP; Lanata CF
• Re-examination of immune response and estimation of anti-Vi IgG protective threshold against typhoid fever-based on the efficacy trial of Vi conjugate in young children.
  Vaccine Volume: 32 Page(s): 2359 - 2363
  04/25/2014 Authors: Szu SC; Klugman KP; Hunt S
• Randomized, placebo-controlled trial on safety and efficacy of inactivated influenza vaccination of pregnant women in preventing illness in their infants
  INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES Volume: 21 Page(s): 32 - 32
  04/01/2014 Authors: Madhi S; Cutland C; Jones S; Hugo A; Treurnicht FK; Kuwanda L; Klugman K; Ortiz J; Neuzil K; Simoes EAF
• Efficacy and immunogenicity of inactivated influenza vaccine in pregnant women: A randomized, double-blind, placebo controlled trial
  INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES Volume: 21 Page(s): 430 - 431
  04/01/2014 Authors: Madhi S; Cutland C; Hugo A; Jones S; Kuwanda L; Dighero B; Treurnicht FK; Klugman K; Venter M; Simoes EAF
• A tale of 2 pneumococcal vaccines.
  Clin Infect Dis Volume: 58 Page(s): 925 - 927
  04/01/2014 Authors: Klugman KP
• Surveillance for antimicrobial drug resistance in under-resourced countries.
  Emerg Infect Dis Volume: 20 Page(s): 434 - 441
  03/01/2014 Authors: Vernet G; Mary C; Altmann DM; Doumbo O; Morpeth S; Bhutta ZA; Klugman KP
• Live attenuated influenza vaccine enhances colonization of Streptococcus pneumoniae and Staphylococcus aureus in mice.
  mBio Volume: 5
  02/18/2014 Authors: Mina MJ; McCullers JA; Klugman KP
• Determinants of invasiveness beneath the capsule of the pneumococcus.
  J Infect Dis Volume: 209 Page(s): 321 - 322
  02/01/2014 Authors: Klugman KP; Bentley SD; McGee L
• HIV and influenza virus infections are associated with increased blood pneumococcal load: a prospective, hospital-based observational study in South Africa, 2009-2011.
  J Infect Dis Volume: 209 Page(s): 56 - 65
  01/01/2014 Authors: Wolter N; Cohen C; Tempia S; Madhi SA; Venter M; Moyes J; Walaza S; Malope Kgokong B; Groome M; du Plessis M
• Clinical epidemiology of bocavirus, rhinovirus, two polyomaviruses and four coronaviruses in HIV-infected and HIV-uninfected South African children.
  PLoS One Volume: 9 Page(s): e86448
  01/01/2014 Authors: Nunes MC; Kuschner Z; Rabede Z; Madimabe R; Van Niekerk N; Moloi J; Kuwanda L; Rossen JW; Klugman KP; Adrian PV
• Global practices of meningococcal vaccine use and impact on invasive disease.
  Pathog Glob Health Volume: 108 Page(s): 11 - 20
  01/01/2014 Authors: Ali A; Jafri RZ; Messonnier N; Tevi-Benissan C; Durrheim D; Eskola J; Fermon F; Klugman KP; Ramsay M; Sow S
• 220D-F2 from Rubus ulmifolius kills Streptococcus pneumoniae planktonic cells and pneumococcal biofilms.
  PLoS One Volume: 9 Page(s): e97314
  01/01/2014 Authors: Talekar SJ; Chochua S; Nelson K; Klugman KP; Quave CL; Vidal JE
• Impact of experimental human pneumococcal carriage on nasopharyngeal bacterial densities in healthy adults.
  PLoS One Volume: 9 Page(s): e98829
  01/01/2014 Authors: Shak JR; Cremers AJH; Gritzfeld JF; de Jonge MI; Hermans PWM; Vidal JE; Klugman KP; Gordon SB
• Mutations within the rplD Gene of Linezolid-Nonsusceptible Streptococcus pneumoniae Strains Isolated in the United States.
  Antimicrob Agents Chemother Volume: 58 Page(s): 2459 - 2462
  01/01/2014 Authors: Dong W; Chochua S; McGee L; Jackson D; Klugman KP; Vidal JE
• The adult nasopharyngeal microbiome as a determinant of pneumococcal acquisition.
  Microbiome Volume: 2 Page(s): 44
  01/01/2014 Authors: Cremers AJ; Zomer AL; Gritzfeld JF; Ferwerda G; van Hijum SA; Ferreira DM; Shak JR; Klugman KP; Boekhorst J; Timmerman HM
• Population snapshot of Streptococcus pneumoniae causing invasive disease in South Africa prior to introduction of pneumococcal conjugate vaccines.
  PLoS One Volume: 9 Page(s): e107666
  01/01/2014 Authors: Ndlangisa KM; du Plessis M; Wolter N; de Gouveia L; Klugman KP; von Gottberg A; GERMS-SA
• Standard method for detecting upper respiratory carriage of Streptococcus pneumoniae: updated recommendations from the World Health Organization Pneumococcal Carriage Working Group.
  Vaccine Volume: 32 Page(s): 165 - 179
  12/17/2013 Authors: Satzke C; Turner P; Virolainen-Julkunen A; Adrian PV; Antonio M; Hare KM; Henao-Restrepo AM; Leach AJ; Klugman KP; Porter BD
• Use of near-real-time medical claims data to generate timely vaccine coverage estimates in the US: the dynamics of PCV13 vaccine uptake.
  Vaccine Volume: 31 Page(s): 5983 - 5988
  12/05/2013 Authors: Schuck-Paim C; Taylor R; Lindley D; Klugman KP; Simonsen L
• Dynamics of pneumococcal transmission in vaccine-naive children and their HIV-infected or HIV-uninfected mothers during the first 2 years of life.
  Am J Epidemiol Volume: 178 Page(s): 1629 - 1637
  12/01/2013 Authors: Shiri T; Auranen K; Nunes MC; Adrian PV; van Niekerk N; de Gouveia L; von Gottberg A; Klugman KP; Madhi SA
• Antibiotic non-susceptibility among Streptococcus pneumoniae and Haemophilus influenzae isolates identified in African cohorts: a meta-analysis of three decades of published studies.
  Int J Antimicrob Agents Volume: 42 Page(s): 482 - 491
  12/01/2013 Authors: Ginsburg AS; Tinkham L; Riley K; Kay NA; Klugman KP; Gill CJ
• Innovations in pneumonia diagnosis and treatment: a call to action on World Pneumonia Day, 2013.
  Lancet Glob Health Volume: 1 Page(s): e326 - e327
  12/01/2013 Authors: Ginsburg AS; Sadruddin S; Klugman KP
• Temporal changes in pneumococcal colonization in a rural African community with high HIV prevalence following routine infant pneumococcal immunization.
  Pediatr Infect Dis J Volume: 32 Page(s): 1270 - 1278
  11/01/2013 Authors: Nzenze SA; Shiri T; Nunes MC; Klugman KP; Kahn K; Twine R; de Gouveia L; von Gottberg A; Madhi SA
• Interrelationship of Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus colonization within and between pneumococcal-vaccine nave mother-child dyads.
  BMC Infect Dis Volume: 13 Page(s): 483
  10/17/2013 Authors: Shiri T; Nunes MC; Adrian PV; Van Niekerk N; Klugman KP; Madhi SA
• Live attenuated influenza vaccine, but not pneumococcal conjugate vaccine, protects against increased density and duration of pneumococcal carriage after influenza infection in pneumococcal colonized mice.
  J Infect Dis Volume: 208 Page(s): 1281 - 1285
  10/15/2013 Authors: Mina MJ; Klugman KP; McCullers JA
• Novel role for the Streptococcus pneumoniae toxin pneumolysin in the assembly of biofilms.
  mBio Volume: 4 Page(s): e00655 - e00613
  09/10/2013 Authors: Shak JR; Ludewick HP; Howery KE; Sakai F; Yi H; Harvey RM; Paton JC; Klugman KP; Vidal JE
• Global epidemiology of invasive meningococcal disease.
  Popul Health Metr Volume: 11 Page(s): 17
  09/10/2013 Authors: Jafri RZ; Ali A; Messonnier NE; Tevi-Benissan C; Durrheim D; Eskola J; Fermon F; Klugman KP; Ramsay M; Sow S
• Childhood pneumonia in developing countries.
  Lancet Respir Med Volume: 1 Page(s): 574 - 584
  09/01/2013 Authors: Izadnegahdar R; Cohen AL; Klugman KP; Qazi SA
• Epidemiology of Group B Streptococcus in developing countries.
  Vaccine Volume: 31 Suppl 4 Page(s): D43 - D45
  08/28/2013 Authors: Johri AK; Lata H; Yadav P; Dua M; Yang Y; Xu X; Homma A; Barocchi MA; Bottomley MJ; Saul A
• Epidemiology of invasive pneumococcal disease in the pre-conjugate vaccine era: South Africa, 2003-2008.
  Vaccine Volume: 31 Page(s): 4200 - 4208
  08/28/2013 Authors: von Gottberg A; Cohen C; de Gouveia L; Meiring S; Quan V; Whitelaw A; Crowther-Gibson P; Madhi SA; Whitney CG; Klugman KP
• Vaccination prevents resistance in pneumococcal infections
  Volume: 42 Page(s): S11 - S12
  06/01/2013 Authors: Klugman KP
• Impact of 13-valent pneumococcal conjugate vaccine (PCV13) in a pandemic similar to the 2009 H1N1 in the United States.
  BMC Infect Dis Volume: 13 Page(s): 229
  05/21/2013 Authors: McGarry LJ; Gilmore KE; Rubin JL; Klugman KP; Strutton DR; Weinstein MC
• Antihypertensives suppress the emergence of fluoroquinolone-resistant mutants in pneumococci: an in vitro study.
  Int J Med Microbiol Volume: 303 Page(s): 176 - 181
  05/01/2013 Authors: Pletz MW; Michaylov N; Schumacher U; van der Linden M; Duesberg CB; Fuehner T; Klugman KP; Welte T; Makarewicz O
• Acquisition of Streptococcus pneumoniae in pneumococcal conjugate vaccine-nave South African children and their mothers.
  Pediatr Infect Dis J Volume: 32 Page(s): e192 - e205
  05/01/2013 Authors: Nunes MC; Shiri T; van Niekerk N; Cutland CL; Groome MJ; Koen A; von Gottberg A; de Gouveia L; Klugman KP; Adrian PV
• Quorum-sensing systems LuxS/autoinducer 2 and Com regulate Streptococcus pneumoniae biofilms in a bioreactor with living cultures of human respiratory cells.
  Infect Immun Volume: 81 Page(s): 1341 - 1353
  04/01/2013 Authors: Vidal JE; Howery KE; Ludewick HP; Nava P; Klugman KP
• Epidemiology of invasive pneumococcal disease among high-risk adults since the introduction of pneumococcal conjugate vaccine for children.
  Clin Infect Dis Volume: 56 Page(s): e59 - e67
  03/01/2013 Authors: Muhammad RD; Oza-Frank R; Zell E; Link-Gelles R; Narayan KMV; Schaffner W; Thomas A; Lexau C; Bennett NM; Farley MM
• Influence of bacterial interactions on pneumococcal colonization of the nasopharynx.
  Trends Microbiol Volume: 21 Page(s): 129 - 135
  03/01/2013 Authors: Shak JR; Vidal JE; Klugman KP
• Pathogen replication, host inflammation, and disease in the upper respiratory tract.
  Infect Immun Volume: 81 Page(s): 625 - 628
  03/01/2013 Authors: Mina MJ; Klugman KP
• Pneumococcal capsular switching: a historical perspective.
  J Infect Dis Volume: 207 Page(s): 439 - 449
  02/01/2013 Authors: Wyres KL; Lambertsen LM; Croucher NJ; McGee L; von Gottberg A; Liares J; Jacobs MR; Kristinsson KG; Beall BW; Klugman KP
• Density interactions among Streptococcus pneumoniae, Haemophilus influenzae and Staphylococcus aureus in the nasopharynx of young Peruvian children.
  Pediatr Infect Dis J Volume: 32 Page(s): 72 - 77
  01/01/2013 Authors: Chien Y-W; Vidal JE; Grijalva CG; Bozio C; Edwards KM; Williams JV; Griffin MR; Verastegui H; Hartinger SM; Gil AI
• Expression of Streptococcus pneumoniae Virulence-Related Genes in the Nasopharynx of Healthy Children.
  PLoS One Volume: 8 Page(s): e67147
  01/01/2013 Authors: Sakai F; Talekar SJ; Lanata CF; Grijalva CG; Klugman KP; Vidal JE; RESPIRA PERU Group; Investigators Group
• Pneumococcal polysaccharide vaccine efficacy and routine use of conjugate vaccines in infants: there is no need for a vaccine program in older adults at present.
  Clin Infect Dis Volume: 55 Page(s): 1577 - 1579
  12/01/2012 Authors: Trck J; Lazarus R; Jonsdottir I; Klugman KP; Pollard AJ
• The multidrug-resistant PMEN1 pneumococcus is a paradigm for genetic success.
  Genome Biol Volume: 13 Page(s): R103
  11/16/2012 Authors: Wyres KL; Lambertsen LM; Croucher NJ; McGee L; von Gottberg A; Liares J; Jacobs MR; Kristinsson KG; Beall BW; Klugman KP
• Clonal analysis of Neisseria meningitidis serogroup B strains in South Africa, 2002 to 2006: emergence of new clone ST-4240/6688.
  J Clin Microbiol Volume: 50 Page(s): 3678 - 3686
  11/01/2012 Authors: Moodley C; du Plessis M; Ndlangisa K; de Gouveia L; Klugman KP; von Gottberg A; Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa
• Risk factors for multidrug-resistant invasive pneumococcal disease in South Africa, a setting with high HIV prevalence, in the prevaccine era from 2003 to 2008.
  Antimicrob Agents Chemother Volume: 56 Page(s): 5088 - 5095
  10/01/2012 Authors: Crowther-Gibson P; Cohen C; Klugman KP; de Gouveia L; von Gottberg A; Group for Enteric, Respiratory, and Meningeal Disease Surveillance in South Africa (GERMS-SA)
• A century of pneumococcal vaccination research in humans.
  Clin Microbiol Infect Volume: 18 Suppl 5 Page(s): 15 - 24
  10/01/2012 Authors: Grabenstein JD; Klugman KP
• Modeling the impact of the 13-valent pneumococcal conjugate vaccine serotype catch-up program using United States claims data.
  BMC Infect Dis Volume: 12 Page(s): 175
  08/03/2012 Authors: Strutton DR; Farkouh RA; Rubin JL; McGarry LJ; Loiacono PM; Klugman KP; Pelton SI; Gilmore KE; Weinstein MC
• Population snapshot of invasive serogroup B meningococci in South Africa from 2005 to 2008.
  J Clin Microbiol Volume: 50 Page(s): 2577 - 2584
  08/01/2012 Authors: du Plessis M; Moodley C; Mothibeli KM; Fali A; Klugman KP; von Gottberg A; Group for Enteric, Respiratory and Meningeal Disease SurveillanceSouth Africa
• Low Prevalence of fluoroquinolone-resistant Pneumococci and Penumococcal with WRDR-First-step mutation despite high Fluoroquinolone Consumption in Patients with community-acquired Pneumonia
  INFECTION Volume: 40 Page(s): 11 - 11
  08/01/2012 Authors: Pletz MW; van der Linden M; v Baum H; Duesberg CB; Klugman KP; Welte T
• Density of carriage - Can it predict pneumonia?
  INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES Volume: 16 Page(s): E31 - E31
  06/01/2012 Authors: Klugman K
• Future challenges in the elimination of bacterial meningitis.
  Vaccine Volume: 30 Suppl 2 Page(s): B78 - B86
  05/30/2012 Authors: Bottomley MJ; Serruto D; Sfadi MAP; Klugman KP
• Systemic shigellosis in South Africa.
  Clin Infect Dis Volume: 54 Page(s): 1448 - 1454
  05/01/2012 Authors: Keddy KH; Sooka A; Crowther-Gibson P; Quan V; Meiring S; Cohen C; Nana T; Sriruttan C; Seetharam S; Hoosen A
• Economic burden of acute lower respiratory tract infection in South African children.
  Paediatr Int Child Health Volume: 32 Page(s): 65 - 73
  05/01/2012 Authors: Sinha A; Kim S; Ginsberg G; Franklin H; Kohberger R; Strutton D; Madhi SA; Griffiths UK; Klugman KP
• The relationship between pneumococcal serotypes and antibiotic resistance.
  Vaccine Volume: 30 Page(s): 2728 - 2737
  04/05/2012 Authors: Song J-H; Dagan R; Klugman KP; Fritzell B
• Trimethoprim-sulfamethoxazole prophylaxis and antibiotic nonsusceptibility in invasive pneumococcal disease.
  Antimicrob Agents Chemother Volume: 56 Page(s): 1602 - 1605
  03/01/2012 Authors: Soeters HM; von Gottberg A; Cohen C; Quan V; Klugman KP
• Use of a rapid test of pneumococcal colonization density to diagnose pneumococcal pneumonia.
  Clin Infect Dis Volume: 54 Page(s): 601 - 609
  03/01/2012 Authors: Albrich WC; Madhi SA; Adrian PV; van Niekerk N; Mareletsi T; Cutland C; Wong M; Khoosal M; Karstaedt A; Zhao P
• Invasive pneumococcal pneumonia and respiratory virus co-infections.
  Emerg Infect Dis Volume: 18 Page(s): 294 - 297
  02/01/2012 Authors: Zhou H; Haber M; Ray S; Farley MM; Panozzo CA; Klugman KP
• Invasive disease due to Haemophilus influenzae serotype b ten years after routine vaccination, South Africa, 2003-2009.
  Vaccine Volume: 30 Page(s): 565 - 571
  01/11/2012 Authors: von Gottberg A; Cohen C; Whitelaw A; Chhagan M; Flannery B; Cohen AL; de Gouveia L; Plessis MD; Madhi SA; Klugman KP
• The anticipated severity of a "1918-like" influenza pandemic in contemporary populations: the contribution of antibacterial interventions.
  PLoS One Volume: 7 Page(s): e29219
  01/01/2012 Authors: Chien Y-W; Levin BR; Klugman KP
• Development of the Respiratory Index of Severity in Children (RISC) score among young children with respiratory infections in South Africa.
  PLoS One Volume: 7 Page(s): e27793
  01/01/2012 Authors: Reed C; Madhi SA; Klugman KP; Kuwanda L; Ortiz JR; Finelli L; Fry AM
• Benefits to mother and child of influenza vaccination during pregnancy.
  Hum Vaccin Immunother Volume: 8 Page(s): 130 - 137
  01/01/2012 Authors: Omer SB; Bednarczyk R; Madhi SA; Klugman KP
• Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis.
  Lancet Volume: 378 Page(s): 1917 - 1930
  12/03/2011 Authors: Nair H; Brooks WA; Katz M; Roca A; Berkley JA; Madhi SA; Simmerman JM; Gordon A; Sato M; Howie S
• Increased risk of death in human immunodeficiency virus-infected children with pneumococcal meningitis in South Africa, 2003-2005.
  Pediatr Infect Dis J Volume: 30 Page(s): 1075 - 1080
  12/01/2011 Authors: Nyasulu P; Cohen C; De Gouveia L; Feldman C; Klugman KP; von Gottberg A; Group for Enteric, Respiratory and Meningeal Diseases Surveillance in South Africa (GERMS-SA)
• Contribution of vaccines to our understanding of pneumococcal disease.
  Philos Trans R Soc Lond B Biol Sci Volume: 366 Page(s): 2790 - 2798
  10/12/2011 Authors: Klugman KP
• The LuxS-dependent quorum-sensing system regulates early biofilm formation by Streptococcus pneumoniae strain D39.
  Infect Immun Volume: 79 Page(s): 4050 - 4060
  10/01/2011 Authors: Vidal JE; Ludewick HP; Kunkel RM; Zhner D; Klugman KP
• Outpatient antibiotic prescribing and nonsusceptible Streptococcus pneumoniae in the United States, 1996-2003.
  Clin Infect Dis Volume: 53 Page(s): 631 - 639
  10/01/2011 Authors: Hicks LA; Chien Y-W; Taylor TH; Haber M; Klugman KP; Active Bacterial Core Surveillance (ABCs) Team
• International pneumococcal clones match or exceed the fitness of other strains despite the accumulation of antibiotic resistance.
  Antimicrob Agents Chemother Volume: 55 Page(s): 4915 - 4917
  10/01/2011 Authors: Rudolf D; Michaylov N; van der Linden M; Hoy L; Klugman KP; Welte T; Pletz MW; CAPNETZ Study Group
• Inferior quantitative and qualitative immune responses to pneumococcal conjugate vaccine in infants with nasopharyngeal colonization by Streptococcus pneumoniae during the primary series of immunization.
  Vaccine Volume: 29 Page(s): 6994 - 7001
  09/16/2011 Authors: Madhi SA; Violari A; Klugman KP; Lin G; McIntyre JA; von Gottberg A; Jean-Philippe P; Cotton MF; Adrian P; CIPRA 4 team
• The future of pneumococcal disease prevention.
  Vaccine Volume: 29 Suppl 3 Page(s): C43 - C48
  09/14/2011 Authors: Rodgers GL; Klugman KP
• Use of 2 pneumococcal common protein real-time polymerase chain reaction assays in healthy children colonized with Streptococcus pneumoniae.
  Diagn Microbiol Infect Dis Volume: 70 Page(s): 452 - 454
  08/01/2011 Authors: Rouphael N; Steyn S; Bangert M; Sampson JS; Adrian P; Madhi SA; Klugman KP; Ades EW
• Part IV. Human infections and antibiotic resistance.
  S Afr Med J Volume: 101 Page(s): 567 - 578
  07/28/2011 Authors: Crowther-Gibson P; Govender N; Lewis DA; Bamford C; Brink A; von Gottberg A; Klugman K; du Plessis M; Fali A; Harris B
• The case for launch of an international DNA-based birth cohort study.
  J Glob Health Volume: 1 Page(s): 39 - 45
  06/01/2011 Authors: Rudan I; Chopra M; Aulchenko Y; Baqui AH; Bhutta ZA; Edmond K; Horta BL; Klugman KP; Lanata CF; Madhi SA
• Laboratory-based diagnosis of pneumococcal pneumonia: state of the art and unmet needs.
  Clin Microbiol Infect Volume: 17 Suppl 3 Page(s): 1 - 13
  05/01/2011 Authors: Vernet G; Saha S; Satzke C; Burgess DH; Alderson M; Maisonneuve J-F; Beall BW; Steinhoff MC; Klugman KP
• Maternal influenza immunization and reduced likelihood of prematurity and small for gestational age births: a retrospective cohort study.
  PLoS Med Volume: 8 Page(s): e1000441
  05/01/2011 Authors: Omer SB; Goodman D; Steinhoff MC; Rochat R; Klugman KP; Stoll BJ; Ramakrishnan U
• Timing of serotype 1 pneumococcal disease suggests the need for evaluation of a booster dose.
  Vaccine Volume: 29 Page(s): 3372 - 3373
  04/18/2011 Authors: Klugman KP; Madhi SA; Adegbola RA; Cutts F; Greenwood B; Hausdorff WP
• A framework for global surveillance of antibiotic resistance.
  Drug Resist Updat Volume: 14 Page(s): 79 - 87
  04/01/2011 Authors: Grundmann H; Klugman KP; Walsh T; Ramon-Pardo P; Sigauque B; Khan W; Laxminarayan R; Heddini A; Stelling J
• Distribution of factor H binding protein beyond serogroup B: variation among five serogroups of invasive Neisseria meningitidis in South Africa.
  Vaccine Volume: 29 Page(s): 2187 - 2192
  03/03/2011 Authors: Mothibeli KM; du Plessis M; von Gottberg A; Murphy E; Hoiseth SK; Zlotnick G; Klugman KP
• The impact of antiretroviral treatment on the burden of invasive pneumococcal disease in South African children: a time series analysis.
  AIDS Volume: 25 Page(s): 453 - 462
  02/20/2011 Authors: Nunes MC; von Gottberg A; de Gouveia L; Cohen C; Moore DP; Klugman KP; Madhi SA
• Rapid pneumococcal evolution in response to clinical interventions.
  Science Volume: 331 Page(s): 430 - 434
  01/28/2011 Authors: Croucher NJ; Harris SR; Fraser C; Quail MA; Burton J; van der Linden M; McGee L; von Gottberg A; Song JH; Ko KS
• Impact of pneumococcal conjugate vaccination of infants on pneumonia and influenza hospitalization and mortality in all age groups in the United States.
  mBio Volume: 2 Page(s): e00309 - e00310
  01/25/2011 Authors: Simonsen L; Taylor RJ; Young-Xu Y; Haber M; May L; Klugman KP
• The remaining challenge of pneumonia: the leading killer of children.
  Pediatr Infect Dis J Volume: 30 Page(s): 1 - 2
  01/01/2011 Authors: Dagan R; Bhutta ZA; de Quadros CA; Garau J; Klugman KP; Khuri-Bulos N; Levine O; Saha SK; Sow S; Were F
• Low prevalence of fluoroquinolone resistant strains and resistance precursor strains in Streptococcus pneumoniae from patients with community-acquired pneumonia despite high fluoroquinolone usage.
  Int J Med Microbiol Volume: 301 Page(s): 53 - 57
  01/01/2011 Authors: Pletz MW; van der Linden M; von Baum H; Duesberg CB; Klugman KP; Welte T; CAPNETZ study group
• Analyses of pediatric isolates of Cryptococcus neoformans from South Africa.
  J Clin Microbiol Volume: 49 Page(s): 307 - 314
  01/01/2011 Authors: Miglia KJ; Govender NP; Rossouw J; Meiring S; Mitchell TG; Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa
• Conserved mutations in the pneumococcal bacteriocin transporter gene, blpA, result in a complex population consisting of producers and cheaters.
  mBio Volume: 2
  01/01/2011 Authors: Son MR; Shchepetov M; Adrian PV; Madhi SA; de Gouveia L; von Gottberg A; Klugman KP; Weiser JN; Dawid S
• Communicating trends in resistance using a drug resistance index.
  BMJ Open Volume: 1 Page(s): e000135
  01/01/2011 Authors: Laxminarayan R; Klugman KP
• Persistent high burden of invasive pneumococcal disease in South African HIV-infected adults in the era of an antiretroviral treatment program.
  PLoS One Volume: 6 Page(s): e27929
  01/01/2011 Authors: Nunes MC; von Gottberg A; de Gouveia L; Cohen C; Kuwanda L; Karstaedt AS; Klugman KP; Madhi SA
• Role of Streptococcus pneumoniae in hospitalization for acute community-acquired pneumonia associated with culture-confirmed Mycobacterium tuberculosis in children: a pneumococcal conjugate vaccine probe study.
  Pediatr Infect Dis J Volume: 29 Page(s): 1099 - 1004
  12/01/2010 Authors: Moore DP; Klugman KP; Madhi SA
• Efficacy of whole-cell killed bacterial vaccines in preventing pneumonia and death during the 1918 influenza pandemic.
  J Infect Dis Volume: 202 Page(s): 1639 - 1648
  12/01/2010 Authors: Chien Y-W; Klugman KP; Morens DM
• Public health and economic impact of the 13-valent pneumococcal conjugate vaccine (PCV13) in the United States.
  Vaccine Volume: 28 Page(s): 7634 - 7643
  11/10/2010 Authors: Rubin JL; McGarry LJ; Strutton DR; Klugman KP; Pelton SI; Gilmore KE; Weinstein MC
• Marking November 12, 2010 - World Pneumonia Day: where are we, where are vaccines?
  Hum Vaccin Volume: 6 Page(s): 922 - 925
  11/01/2010 Authors: Dagan R; de Quadros CA; Garau J; Klugman KP; Khuri-Bulos N; Levine O; Sow S; Yang Y
• Single report of -lactam resistance in an invasive Haemophilus influenzae isolate from South Africa mediated by mutations in penicillin-binding protein 3, 2003-2008.
  Int J Antimicrob Agents Volume: 36 Page(s): 480 - 482
  11/01/2010 Authors: Fali A; du Plessis M; Wolter N; Klugman KP; von Gottberg A
• The paradox in pneumococcal serotypes: highly invasive does not mean highly lethal.
  Eur Respir J Volume: 36 Page(s): 712 - 713
  10/01/2010 Authors: Pletz MW; Welte T; Klugman KP
• Invasive Neisseria meningitidis with decreased susceptibility to fluoroquinolones in South Africa, 2009.
  J Antimicrob Chemother Volume: 65 Page(s): 2258 - 2260
  10/01/2010 Authors: du Plessis M; de Gouveia L; Skosana H; Thomas J; Blumberg L; Klugman KP; von Gottberg A; GERMS-SA
• Association of serotype with risk of death due to pneumococcal pneumonia: a meta-analysis.
  Clin Infect Dis Volume: 51 Page(s): 692 - 699
  09/15/2010 Authors: Weinberger DM; Harboe ZB; Sanders EAM; Ndiritu M; Klugman KP; Rckinger S; Dagan R; Adegbola R; Cutts F; Johnson HL
• Invasive infections and sickle-cell disease.
  Lancet Infect Dis Volume: 10 Page(s): 593
  09/01/2010 Authors: Adamkiewicz T
• Effect of HIV infection status and anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants.
  J Infect Dis Volume: 202 Page(s): 355 - 361
  08/15/2010 Authors: Madhi SA; Adrian P; Cotton MF; McIntyre JA; Jean-Philippe P; Meadows S; Nachman S; Kyhty H; Klugman KP; Violari A
• Antimicrobial susceptibility of pneumococcal isolates causing bacteraemic pneumococcal pneumonia: analysis using current breakpoints and fluoroquinolone pharmacodynamics.
  Int J Antimicrob Agents Volume: 36 Page(s): 95 - 97
  07/01/2010 Authors: Feldman C; Brink AJ; von Gottberg A; Wolter N; de Gouveia L; Perovic O; Klugman KP
• Increased incidence of meningococcal disease in HIV-infected individuals associated with higher case-fatality ratios in South Africa.
  AIDS Volume: 24 Page(s): 1351 - 1360
  06/01/2010 Authors: Cohen C; Singh E; Wu HM; Martin S; de Gouveia L; Klugman KP; Meiring S; Govender N; von Gottberg A; Group for Enteric, Respiratory and Meningeal disease Surveillance in South Africa (GERMS-SA)
• PUBLIC HEALTH AND ECONOMIC IMPACT OF 13-VALENT PNEUMOCOCCAL CONJUGATE VACCINE (PCV13) IN AN INFLUENZA PANDEMIC IN SINGAPORE AND HONG KONG
  VALUE IN HEALTH Volume: 13 Page(s): A9 - A9
  05/01/2010 Authors: Rubin J; McGarry L; Klugman K; Strutton D; Gilmore K; Hwang S; Rinaldi F; Weinstein M
• Increased risk of invasive bacterial infections in African people with sickle-cell disease: a systematic review and meta-analysis.
  Lancet Infect Dis Volume: 10 Page(s): 329 - 337
  05/01/2010 Authors: Ramakrishnan M; Mosi JC; Klugman KP; Iglesias JMF; Grant LR; Mpoudi-Etame M; Levine OS
• Pneumococcal infection and colonization in children and its impact on pneumococcal disease in adults
  INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES Volume: 14 Page(s): E313 - E313
  03/01/2010 Authors: Klugman K
• Lessons from 1918 and the current H1N1 pandemic on the role of bacterial infections during pandemic influenza
  INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES Volume: 14 Page(s): E182 - E183
  03/01/2010 Authors: Klugman K
• Public health and economic impact of vaccination with 7-valent pneumococcal vaccine (PCV7) in the context of the annual influenza epidemic and a severe influenza pandemic.
  BMC Infect Dis Volume: 10 Page(s): 14
  01/21/2010 Authors: Rubin JL; McGarry LJ; Klugman KP; Strutton DR; Gilmore KE; Weinstein MC
• An unusual pneumococcal sequence type is the predominant cause of serotype 3 invasive disease in South Africa.
  J Clin Microbiol Volume: 48 Page(s): 184 - 191
  01/01/2010 Authors: Mothibeli KM; du Plessis M; von Gottberg A; de Gouveia L; Adrian P; Madhi SA; Klugman KP; Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa (GERMS-SA)
• Bacterial pathogens and death during the 1918 influenza pandemic.
  N Engl J Med Volume: 361 Page(s): 2582 - 2583
  12/24/2009 Authors: Chien Y-W; Klugman KP; Morens DM
• Chlorhexidine maternal-vaginal and neonate body wipes in sepsis and vertical transmission of pathogenic bacteria in South Africa: a randomised, controlled trial.
  Lancet Volume: 374 Page(s): 1909 - 1916
  12/05/2009 Authors: Cutland CL; Madhi SA; Zell ER; Kuwanda L; Laque M; Groome M; Gorwitz R; Thigpen MC; Patel R; Velaphi SC
• Cost-effectiveness of pneumococcal conjugate vaccine: an update after 7 years of use in the United States.
  Vaccine Volume: 27 Page(s): 6483 - 6494
  11/05/2009 Authors: Ray GT; Pelton SI; Klugman KP; Strutton DR; Moore MR
• Editorial: Breathing new life into pneumonia epidemiology.
  Am J Epidemiol Volume: 170 Page(s): 1067 - 1068
  11/01/2009 Authors: Levine OS; Klugman KP
• A preventable killer: Pneumonia.
  Clin Microbiol Infect Volume: 15 Page(s): 989 - 990
  11/01/2009 Authors: Klugman KP; PACE (Pneumococcal Advisory Council of Experts); Garau J; ESCMID (European Society of Clinical Microbiology and Infection)
• Pneumonia vaccines for all who need them.
  Hum Vaccin Volume: 5 Page(s): 779 - 780
  11/01/2009 Authors: Klugman KP; Dagan R; Pneumococcal Awareness Council of Experts (PACE)
• Genotypic comparison of invasive Neisseria meningitidis serogroup Y isolates from the United States, South Africa, and Israel, isolated from 1999 through 2002.
  J Clin Microbiol Volume: 47 Page(s): 2787 - 2793
  09/01/2009 Authors: Whitney AM; Coulson GB; von Gottberg A; Block C; Keller N; Mayer LW; Messonnier NE; Klugman KP
• Severity of illness scoring systems in patients with bacteraemic pneumococcal pneumonia: implications for the intensive care unit care.
  Clin Microbiol Infect Volume: 15 Page(s): 850 - 857
  09/01/2009 Authors: Feldman C; Alanee S; Yu VL; Richards GA; Ortqvist A; Rello J; Chiou CCC; Chedid MBF; Wagener MM; Klugman KP
• Pneumococcal pneumonia and influenza: a deadly combination.
  Vaccine Volume: 27 Suppl 3 Page(s): C9 - C14
  08/21/2009 Authors: Klugman KP; Chien Y-W; Madhi SA
• 3-monthly azithromycin administration for trachoma.
  Lancet Volume: 374 Page(s): 449
  08/08/2009 Authors: Malhotra-Kumar S; Coenen S; Klugman KP; Goossens H
• Sequence diversity of the factor H binding protein vaccine candidate in epidemiologically relevant strains of serogroup B Neisseria meningitidis.
  Volume: 200 Page(s): 379 - 389
  08/01/2009 Authors: Murphy E; Andrew L; Lee K-L; Dilts DA; Nunez L; Fink PS; Ambrose K; Borrow R; Findlow J; Taha M-K
• Examination of AUICs for Streptococcus pneumoniae (SP) in patients with CAP failing to respond to outpatient beta-lactams (BL)
  Volume: 34 Page(s): S30 - S30
  07/01/2009 Authors: Schentag J; Klugman K; Wilton G; Paladino J
• Rationale for revised penicillin susceptibility breakpoints versus Streptococcus pneumoniae: coping with antimicrobial susceptibility in an era of resistance.
  Clin Infect Dis Volume: 48 Page(s): 1596 - 1600
  06/01/2009 Authors: Weinstein MP; Klugman KP; Jones RN
• Molecular characterization of emerging non-levofloxacin-susceptible pneumococci isolated from children in South Africa.
  J Clin Microbiol Volume: 47 Page(s): 1319 - 1324
  05/01/2009 Authors: Wolter N; du Plessis M; von Gottberg A; de Gouveia L; Klugman KP
• Quantitative and qualitative anamnestic immune responses to pneumococcal conjugate vaccine in HIV-infected and HIV-uninfected children 5 years after vaccination.
  J Infect Dis Volume: 199 Page(s): 1168 - 1176
  04/15/2009 Authors: Madhi SA; Klugman KP; Kuwanda L; Cutland C; Kyhty H; Adrian P
• Recommendations for treatment of childhood non-severe pneumonia.
  Lancet Infect Dis Volume: 9 Page(s): 185 - 196
  03/01/2009 Authors: Grant GB; Campbell H; Dowell SF; Graham SM; Klugman KP; Mulholland EK; Steinhoff M; Weber MW; Qazi S; World Health Organization Department of Child and Adolescent Health and Development
• Time from illness onset to death, 1918 influenza and pneumococcal pneumonia.
  Emerg Infect Dis Volume: 15 Page(s): 346 - 347
  02/01/2009 Authors: Klugman KP; Astley CM; Lipsitch M
• In vitro evaluation of the antimicrobial activity of ceftaroline against cephalosporin-resistant isolates of Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 53 Page(s): 552 - 556
  02/01/2009 Authors: McGee L; Biek D; Ge Y; Klugman M; du Plessis M; Smith AM; Beall B; Whitney CG; Klugman KP
• Antimicrobial Susceptibility of Pneumococcal Isolates Causing Bacteremic Community-Acquired Pneumonia in Gauteng, South Africa
  AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 179
  01/01/2009 Authors: Feldman C; Brink AJ; von Gottberg A; Wolter N; de Gouveia L; Perovic O; Klugman KP
• Resistance in Streptococcus pneumoniae
  Page(s): 681 - 693
  01/01/2009 Authors: McGee L; Klugman KP
• A disease model descriptive of progression between chronic obstructive pulmonary disease exacerbations and community-acquired pneumonia: roles for underlying lung disease and the pharmacokinetics/pharmacodynamics of the antibiotic.
  Int J Antimicrob Agents Volume: 33 Page(s): 58 - 64
  01/01/2009 Authors: File TM; Monte SV; Schentag JJ; Paladino JA; Klugman KP; Lavin B; Yu VL; Singer ME; Adelman MH
• The significance of serotype replacement for pneumococcal disease and antibiotic resistance.
  Adv Exp Med Biol Volume: 634 Page(s): 121 - 128
  01/01/2009 Authors: Klugman KP
• Increased Risk of Death in HIV-Infected Patients with Pneumococcal Meningitis, South Africa, 2003-2005
  INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES Volume: 12 Page(s): E46 - E47
  12/01/2008 Authors: Nyasulu P; Cohen C; von Gottberg A; de Gouveia L; Quan V; Feldman C; Klugman KP
• Novel approaches to the identification of Streptococcus pneumoniae as the cause of community-acquired pneumonia.
  Clin Infect Dis Volume: 47 Suppl 3 Page(s): S202 - S206
  12/01/2008 Authors: Klugman KP; Madhi SA; Albrich WC
• Impact of conjugate pneumococcal vaccines on antibiotic resistance.
  Lancet Infect Dis Volume: 8 Page(s): 785 - 795
  12/01/2008 Authors: Dagan R; Klugman KP
• Antimicrobial susceptibility and molecular epidemiology of Streptococcus pneumoniae isolated from Shanghai, China.
  Int J Antimicrob Agents Volume: 32 Page(s): 386 - 391
  11/01/2008 Authors: Yang F; Xu X-G; Yang M-J; Zhang Y-Y; Klugman KP; McGee L
• Serotype 6C is associated with penicillin-susceptible meningeal infections in human immunodeficiency virus (HIV)-infected adults among invasive pneumococcal isolates previously identified as serotype 6A in South Africa.
  Int J Antimicrob Agents Volume: 32 Suppl 1 Page(s): S66 - S70
  11/01/2008 Authors: du Plessis M; von Gottberg A; Madhi SA; Hattingh O; de Gouveia L; Klugman KP; Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa (GERMS-SA)
• Interspecies recombination occurs frequently in quinolone resistance-determining regions of clinical isolates of Streptococcus pyogenes.
  Antimicrob Agents Chemother Volume: 52 Page(s): 4191 - 4193
  11/01/2008 Authors: Duesberg CB; Malhotra-Kumar S; Goossens H; McGee L; Klugman KP; Welte T; Pletz MWR
• Neisseria meningitidis intermediately resistant to penicillin and causing invasive disease in South Africa in 2001 to 2005.
  J Clin Microbiol Volume: 46 Page(s): 3208 - 3214
  10/01/2008 Authors: du Plessis M; von Gottberg A; Cohen C; de Gouveia L; Klugman KP; Group for Enteric Respiratory and Meningeal Disease Surveillance in South Africa (GERMS-SA)
• Interaction between influenza virus and Streptococcus pneumoniae in severe pneumonia.
  Expert Rev Respir Med Volume: 2 Page(s): 663 - 672
  10/01/2008 Authors: Madhi SA; Schoub B; Klugman KP
• Molecular basis and clonal nature of increasing pneumococcal macrolide resistance in South Africa, 2000-2005.
  Int J Antimicrob Agents Volume: 32 Page(s): 62 - 67
  07/01/2008 Authors: Wolter N; von Gottberg A; du Plessis M; de Gouveia L; Klugman KP; Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa
• Mortality in penicillin-resistant pneumococcal meningitis.
  Pediatr Infect Dis J Volume: 27 Page(s): 671 - 672
  07/01/2008 Authors: Klugman KP; Walsh AL; Phiri A; Molyneux EM
• Apnea and its possible relationship to immunization in ex-premature infants.
  Vaccine Volume: 26 Page(s): 3410 - 3413
  06/25/2008 Authors: Cooper PA; Madhi SA; Huebner RE; Mbelle N; Karim SSA; Kleinschmidt I; Forrest BD; Klugman KP
• Emergence of levofloxacin-non-susceptible Streptococcus pneumoniae and treatment for multidrug-resistant tuberculosis in children in South Africa: a cohort observational surveillance study.
  Lancet Volume: 371 Page(s): 1108 - 1113
  03/29/2008 Authors: von Gottberg A; Klugman KP; Cohen C; Wolter N; de Gouveia L; du Plessis M; Mpembe R; Quan V; Whitelaw A; Hoffmann R
• Impact of cotrimoxazole on non-susceptibility to antibiotics in Streptococcus pneumoniae carriage isolates among HIV-infected mineworkers in South Africa.
  J Infect Volume: 56 Page(s): 171 - 178
  03/01/2008 Authors: Pemba L; Charalambous S; von Gottberg A; Magadla B; Moloi V; Seabi O; Wasas A; Klugman KP; Chaisson RE; Fielding K
• Influenza guideline for South Africa--update 2008.
  S Afr Med J Volume: 98 Page(s): 224 - 230
  03/01/2008 Authors: Green RJ; Feldman C; Schoub B; Richards GA; Madhi SA; Zar HJ; Lalloo U; Guideline Committee of 1999; Klugman K; Phillips D
• Telithromycin resistance in Streptococcus pneumoniae is conferred by a deletion in the leader sequence of erm(B) that increases rRNA methylation.
  Antimicrob Agents Chemother Volume: 52 Page(s): 435 - 440
  02/01/2008 Authors: Wolter N; Smith AM; Farrell DJ; Northwood JB; Douthwaite S; Klugman KP
• Emergence of endemic serogroup W135 meningococcal disease associated with a high mortality rate in South Africa.
  Clin Infect Dis Volume: 46 Page(s): 377 - 386
  02/01/2008 Authors: von Gottberg A; du Plessis M; Cohen C; Prentice E; Schrag S; de Gouveia L; Coulson G; de Jong G; Klugman K; Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa
• Pneumococcal Vaccines The Impact of Conjugate Vaccine Conclusions
  Page(s): 437 - 439
  01/01/2008 Authors: Siber GR; Klugman KP; Makela PH
• Emergence, Spread, and Extinction of Pathogenic Bacterial Clones
  Page(s): 185 - 195
  01/01/2008 Authors: McGee L; Tenover FC; Beall B; Klugman KP
• Impact of Conjugate Pneumococcal Vaccine on Antibiotic Resistance
  Page(s): 369 - 385
  01/01/2008 Authors: Dagan R; Klugman KP
• Efficacy and Safety of Conjugate Pneumococcal Vaccine in the Prevention of Pneumonia
  Page(s): 327 - 337
  01/01/2008 Authors: Madhi SA; Klugman KP
• Pneumococcal Vaccines The Impact of Conjugate Vaccine Preface
  Page(s): XIX - XIX
  01/01/2008 Authors: Siber GR; Klugman KP; Makela PH
• Public Health and Economic Impact of 7-valent Pneumococcal Conjugate Vaccination in an Influenza Pandemic in the US
  
  01/01/2008 Authors: Rubin JL; McGarry LJ; Klugman K; Strutton D; Ciuryla V; Gilmore K
• Meta-Analysis of the Efficacy of Conjugate Vaccines against Invasive Pneumococcal Disease
  Page(s): 317 - 326
  01/01/2008 Authors: Klugman KP; Cutts F; Adegbola RA; Black S; Madhi SA; O'Brien KL; Santosham M; Shinefield H; Sterne JAC
• Introduction: historical perspective and development of amoxicillin/clavulanate.
  Int J Antimicrob Agents Volume: 30 Suppl 2 Page(s): S109 - S112
  12/01/2007 Authors: Geddes AM; Klugman KP; Rolinson GN
• Long-term effect of pneumococcal conjugate vaccine on nasopharyngeal colonization by Streptococcus pneumoniae--and associated interactions with Staphylococcus aureus and Haemophilus influenzae colonization--in HIV-Infected and HIV-uninfected children.
  J Infect Dis Volume: 196 Page(s): 1662 - 1666
  12/01/2007 Authors: Madhi SA; Adrian P; Kuwanda L; Cutland C; Albrich WC; Klugman KP
• Comparison of the effects of macrolides, amoxicillin, ceftriaxone, doxycycline, tobramycin and fluoroquinolones, on the production of pneumolysin by Streptococcus pneumoniae in vitro.
  J Antimicrob Chemother Volume: 60 Page(s): 1155 - 1158
  11/01/2007 Authors: Anderson R; Steel HC; Cockeran R; von Gottberg A; de Gouveia L; Klugman KP; Mitchell TJ; Feldman C
• Risk factors for antibiotic resistance in Streptococcus pneumoniae
  SAMJ SOUTH AFRICAN MEDICAL JOURNAL Volume: 97 Page(s): 1129 - 1132
  11/01/2007 Authors: Klugman KP
• Risk factors for antibiotic resistance in Streptococcus pneumoniae.
  S Afr Med J Volume: 97 Page(s): 1129 - 1132
  11/01/2007 Authors: Klugman KP
• [Complex choices in respiratory tract infections: the search for simple solutions].
  Med Mal Infect Volume: 37 Spec No 1 Page(s): 1
  11/01/2007 Authors: Klugman K; Lode H
• [Clinical impact of antibiotic resistance in respiratory tract infections].
  Med Mal Infect Volume: 37 Spec No 1 Page(s): 6 - 10
  11/01/2007 Authors: Klugman K
• Streptococcus pneumoniae bacteraemia: pharmacodynamic correlations with outcome and macrolide resistance--a controlled study.
  Int J Antimicrob Agents Volume: 30 Page(s): 264 - 269
  09/01/2007 Authors: Schentag JJ; Klugman KP; Yu VL; Adelman MH; Wilton GJ; Chiou CC; Patel M; Lavin B; Paladino JA
• Bacteraemic pneumococcal pneumonia: impact of HIV on clinical presentation and outcome.
  J Infect Volume: 55 Page(s): 125 - 135
  08/01/2007 Authors: Feldman C; Klugman KP; Yu VL; Ortqvist A; Choiu CCC; Chedid MBF; Rello J; Wagener M; International Pneumococcal Study Group
• Seasonality, incidence, and repeat human metapneumovirus lower respiratory tract infections in an area with a high prevalence of human immunodeficiency virus type-1 infection.
  Pediatr Infect Dis J Volume: 26 Page(s): 693 - 699
  08/01/2007 Authors: Madhi SA; Ludewick H; Kuwanda L; van Niekerk N; Cutland C; Klugman KP
• Herd immunity after pneumococcal conjugate vaccination.
  Lancet Volume: 370 Page(s): 218 - 219
  07/21/2007 Authors: Albrich WC; Madhi SA; Lafond KE; Klugman KP
• Association of serotypes of Streptococcus pneumoniae with disease severity and outcome in adults: an international study.
  Clin Infect Dis Volume: 45 Page(s): 46 - 51
  07/01/2007 Authors: Alanee SRJ; McGee L; Jackson D; Chiou CC; Feldman C; Morris AJ; Ortqvist A; Rello J; Luna CM; Baddour LM
• Virulence characteristics of Klebsiella and clinical manifestations of K. pneumoniae bloodstream infections.
  Emerg Infect Dis Volume: 13 Page(s): 986 - 993
  07/01/2007 Authors: Yu VL; Hansen DS; Ko WC; Sagnimeni A; Klugman KP; von Gottberg A; Goossens H; Wagener MM; Benedi VJ; International Klebseilla Study Group
• Resurgence of the multiresistant pneumococcus in the United States: a commentary.
  Pediatr Infect Dis J Volume: 26 Page(s): 473 - 474
  06/01/2007 Authors: Klugman KP; McGee L
• Resurgence of the multiresistant pneumococcus in the United States: A commentary
  PEDIATRIC INFECTIOUS DISEASE JOURNAL Volume: 26 Page(s): 473 - 474
  06/01/2007 Authors: Klugman KP; McGee L
• Estimating the protective concentration of anti-pneumococcal capsular polysaccharide antibodies.
  Vaccine Volume: 25 Page(s): 3816 - 3826
  05/10/2007 Authors: Siber GR; Chang I; Baker S; Fernsten P; O'Brien KL; Santosham M; Klugman KP; Madhi SA; Paradiso P; Kohberger R
• Usefulness of C-reactive protein to define pneumococcal conjugate vaccine efficacy in the prevention of pneumonia. (vol 25, pg 30, 2006)
  PEDIATRIC INFECTIOUS DISEASE JOURNAL Volume: 26 Page(s): 458 - 458
  05/01/2007 Authors: Madhi SA; Kohler M; Kuwanda L; Cutland C; Klugman KP
• Pneumococcal vaccines and flu preparedness.
  Science Volume: 316 Page(s): 49 - 50
  04/06/2007 Authors: Klugman KP; Madhi SA
• World Health Organisation definition of "radiologically-confirmed pneumonia" may under-estimate the true public health value of conjugate pneumococcal vaccines.
  Vaccine Volume: 25 Page(s): 2413 - 2419
  03/22/2007 Authors: Madhi SA; Klugman KP
• Long-term immunogenicity and efficacy of a 9-valent conjugate pneumococcal vaccine in human immunodeficient virus infected and non-infected children in the absence of a booster dose of vaccine.
  Vaccine Volume: 25 Page(s): 2451 - 2457
  03/22/2007 Authors: Madhi SA; Adrian P; Kuwanda L; Jassat W; Jones S; Little T; Soininen A; Cutland C; Klugman KP
• High-level telithromycin resistance in a clinical isolate of Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 51 Page(s): 1092 - 1095
  03/01/2007 Authors: Wolter N; Smith AM; Low DE; Klugman KP
• Recent discoveries in prevention of pneumococcal disease
  Volume: 29 Page(s): S11 - S12
  03/01/2007 Authors: Klugman K
• Meningococcal disease in South Africa, 1999-2002.
  Emerg Infect Dis Volume: 13 Page(s): 273 - 281
  02/01/2007 Authors: Coulson GB; von Gottberg A; du Plessis M; Smith AM; de Gouveia L; Klugman KP; Group for Enteric, Respiratory and Meningeal Disease Surveillance in South Africa
• Clinical impact of antibiotic resistance in respiratory tract infections.
  Int J Antimicrob Agents Volume: 29 Suppl 1 Page(s): S6 - 10
  02/01/2007 Authors: Klugman KP
• Increased antimicrobial resistance among nonvaccine serotypes of Streptococcus pneumoniae in the pediatric population after the introduction of 7-valent pneumococcal vaccine in the United States.
  Pediatr Infect Dis J Volume: 26 Page(s): 123 - 128
  02/01/2007 Authors: Farrell DJ; Klugman KP; Pichichero M
• Clarithromycin alone and in combination with ceftriaxone inhibits the production of pneumolysin by both macrolide-susceptible and macrolide-resistant strains of Streptococcus pneumoniae.
  J Antimicrob Chemother Volume: 59 Page(s): 224 - 229
  02/01/2007 Authors: Anderson R; Steel HC; Cockeran R; Smith AM; von Gottberg A; de Gouveia L; Brink A; Klugman KP; Mitchell TJ; Feldman C
• HIV and pneumococcal disease.
  Curr Opin Infect Dis Volume: 20 Page(s): 11 - 15
  02/01/2007 Authors: Klugman KP; Madhi SA; Feldman C
• Fitness costs of fluoroquinolone resistance in Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 51 Page(s): 412 - 416
  02/01/2007 Authors: Rozen DE; McGee L; Levin BR; Klugman KP
• Conjugate vaccines as probes to define the burden of pneumococcal and Haemophilus influenzae Type b pneumonia as well as the role of viruses in the pathogenesis of pneumonia
  Volume: 7 Page(s): 215 - +
  01/01/2007 Authors: Klugman KP; Madhi SA
• Nasopharyngeal colonization: a target for pneumococcal vaccination.
  Expert Rev Vaccines Volume: 5 Page(s): 651 - 667
  10/01/2006 Authors: Kyhty H; Auranen K; Nohynek H; Dagan R; Mkel H
• Nosocomial invasive pneumococcal disease (IPD)
  Volume: 130 Page(s): 274S - 275S
  10/01/2006 Authors: Feldman C; von Gottberg A; Sturm W; Karstaedt A; Govender N; Whitelaw A; de Gouveia L; Klugman K
• Impact of conjugate Haemophilus influenzae type b (Hib) vaccine introduction in South Africa.
  Bull World Health Organ Volume: 84 Page(s): 811 - 818
  10/01/2006 Authors: von Gottberg A; de Gouveia L; Madhi SA; du Plessis M; Quan V; Soma K; Huebner R; Flannery B; Schuchat A; Klugman K
• Fluoroquinolone-resistant Streptococcus pneumoniae.
  Emerg Infect Dis Volume: 12 Page(s): 1462 - 1463
  09/01/2006 Authors: Pletz MWR; Fugit RV; McGee L; Glasheen JJ; Keller DL; Welte T; Klugman KP
• No impact of penicillin resistance on mortality.
  Clin Infect Dis Volume: 43 Page(s): 261
  07/15/2006 Authors: Klugman KP; Yu VL
• Five-year cohort study of hospitalization for respiratory syncytial virus associated lower respiratory tract infection in African children.
  J Clin Virol Volume: 36 Page(s): 215 - 221
  07/01/2006 Authors: Madhi SA; Kuwanda L; Cutland C; Klugman KP
• Pneumococcal vaccination in developing countries.
  Lancet Volume: 367 Page(s): 1880 - 1882
  06/10/2006 Authors: Levine OS; O'Brien KL; Knoll M; Adegbola RA; Black S; Cherian T; Dagan R; Goldblatt D; Grange A; Greenwood B
• Antimicrobial resistance--fluoroquinolones and the tiger's tail.
  J Chemother Volume: 18 Page(s): 328 - 330
  06/01/2006 Authors: Tillotson GS; Carroll J; Klugman KP
• The "Achilles heel" of global efforts to combat infectious diseases.
  Clin Infect Dis Volume: 42 Page(s): 1503 - 1504
  05/15/2006 Authors: Berkelman R; Cassell G; Specter S; Hamburg M; Klugman K
• Pneumococcal coinfection with human metapneumovirus.
  J Infect Dis Volume: 193 Page(s): 1236 - 1243
  05/01/2006 Authors: Madhi SA; Ludewick H; Kuwanda L; Niekerk NV; Cutland C; Little T; Klugman KP
• Prevalence of first-step mutants among levofloxacin-susceptible invasive isolates of Streptococcus pneumoniae in the United States.
  Antimicrob Agents Chemother Volume: 50 Page(s): 1561 - 1563
  04/01/2006 Authors: Pletz MWR; Shergill AP; McGee L; Beall B; Whitney CG; Klugman KP; Active Bacterial Core Surveillance Team
• Fluoroquinolone resistance in invasive Streptococcus pyogenes isolates due to spontaneous mutation and horizontal gene transfer.
  Antimicrob Agents Chemother Volume: 50 Page(s): 943 - 948
  03/01/2006 Authors: Pletz MWR; McGee L; Van Beneden CA; Petit S; Bardsley M; Barlow M; Klugman KP
• Heterogeneous macrolide resistance and gene conversion in the pneumococcus.
  Antimicrob Agents Chemother Volume: 50 Page(s): 359 - 361
  01/01/2006 Authors: Wolter N; Smith AM; Farrell DJ; Klugman KP
• Usefulness of C-reactive protein to define pneumococcal conjugate vaccine efficacy in the prevention of pneumonia.
  Pediatr Infect Dis J Volume: 25 Page(s): 30 - 36
  01/01/2006 Authors: Madhi SA; Kohler M; Kuwanda L; Cutland C; Klugman KP
• One enzyme inactivates two antibiotics.
  Nat Med Volume: 12 Page(s): 19 - 20
  01/01/2006 Authors: Klugman KP; Levin BR
• Is combination the only issue?
  AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE Volume: 172 Page(s): 1474 - 1474
  12/01/2005 Authors: Yu VL; Klugman KP; Wagener MM; Chiou CC; Baddour LM
• Immunogenicity and effectiveness of Haemophilus influenzae type b conjugate vaccine in HIV infected and uninfected African children.
  Vaccine Volume: 23 Page(s): 5517 - 5525
  12/01/2005 Authors: Madhi SA; Kuwanda L; Saarinen L; Cutland C; Mothupi R; Kyhty H; Klugman KP
• Amino acid mutations essential to production of an altered PBP 2X conferring high-level beta-lactam resistance in a clinical isolate of Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 49 Page(s): 4622 - 4627
  11/01/2005 Authors: Smith AM; Klugman KP
• Antimicrobial resistance in developing countries. Part II: strategies for containment.
  Lancet Infect Dis Volume: 5 Page(s): 568 - 580
  09/01/2005 Authors: Okeke IN; Klugman KP; Bhutta ZA; Duse AG; Jenkins P; O'Brien TF; Pablos-Mendez A; Laxminarayan R
• Increased prevalence of pediatric pneumococcal serotypes in elderly adults.
  Clin Infect Dis Volume: 41 Page(s): 481 - 487
  08/15/2005 Authors: Feikin DR; Klugman KP; Facklam RR; Zell ER; Schuchat A; Whitney CG; Active Bacterial Core surveillance/Emerging Infections Program Network
• Novel mechanism of resistance to oxazolidinones, macrolides, and chloramphenicol in ribosomal protein L4 of the pneumococcus.
  Antimicrob Agents Chemother Volume: 49 Page(s): 3554 - 3557
  08/01/2005 Authors: Wolter N; Smith AM; Farrell DJ; Schaffner W; Moore M; Whitney CG; Jorgensen JH; Klugman KP
• Antimicrobial resistance in developing countries. Part I: recent trends and current status.
  Lancet Infect Dis Volume: 5 Page(s): 481 - 493
  08/01/2005 Authors: Okeke IN; Laxminarayan R; Bhutta ZA; Duse AG; Jenkins P; O'Brien TF; Pablos-Mendez A; Klugman KP
• Human metapneumovirus genetic variability, South Africa.
  Emerg Infect Dis Volume: 11 Page(s): 1074 - 1078
  07/01/2005 Authors: Ludewick HP; Abed Y; van Niekerk N; Boivin G; Klugman KP; Madhi SA
• Hidden epidemic of macrolide-resistant pneumococci.
  Emerg Infect Dis Volume: 11 Page(s): 802 - 807
  06/01/2005 Authors: Klugman KP; Lonks JR
• Emergence and spread of Streptococcus pneumoniae with erm(B) and mef(A) resistance.
  Emerg Infect Dis Volume: 11 Page(s): 851 - 858
  06/01/2005 Authors: Farrell DJ; Jenkins SG; Brown SD; Patel M; Lavin BS; Klugman KP
• Nasopharyngeal carriage of pneumococcal pediatric serotypes: a risk for acute and recurrent otitis media in children and for invasive disease in susceptible adults.
  J Infect Dis Volume: 191 Page(s): 1790 - 1792
  06/01/2005 Authors: Klugman KP; Welsh KJ
• The impact of a 9-valent pneumococcal conjugate vaccine on the public health burden of pneumonia in HIV-infected and -uninfected children.
  Clin Infect Dis Volume: 40 Page(s): 1511 - 1518
  05/15/2005 Authors: Madhi SA; Kuwanda L; Cutland C; Klugman KP
• Quantitative and qualitative antibody response to pneumococcal conjugate vaccine among African human immunodeficiency virus-infected and uninfected children.
  Pediatr Infect Dis J Volume: 24 Page(s): 410 - 416
  05/01/2005 Authors: Madhi SA; Kuwanda L; Cutland C; Holm A; Kyhty H; Klugman KP
• Altered PBP 2A and its role in the development of penicillin, cefotaxime, and ceftriaxone resistance in a clinical isolate of Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 49 Page(s): 2002 - 2007
  05/01/2005 Authors: Smith AM; Feldman C; Massidda O; McCarthy K; Ndiweni D; Klugman KP
• Capsule homology does not increase the frequency of transformation of linked penicillin binding proteins PBP 1a and PBP 2x in Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 49 Page(s): 1591 - 1592
  04/01/2005 Authors: Trzciski K; MacNeil A; Klugman KP; Lipsitch M
• Use of procalcitonin and C-reactive protein to evaluate vaccine efficacy against pneumonia.
  PLoS Med Volume: 2 Page(s): e38
  02/01/2005 Authors: Madhi SA; Heera JR; Kuwanda L; Klugman KP
• Epidemiological differences among pneumococcal serotypes.
  Lancet Infect Dis Volume: 5 Page(s): 83 - 93
  02/01/2005 Authors: Hausdorff WP; Feikin DR; Klugman KP
• Interspecies recombination in type II topoisomerase genes is not a major cause of fluoroquinolone resistance in invasive Streptococcus pneumoniae isolates in the United States.
  Antimicrob Agents Chemother Volume: 49 Page(s): 779 - 780
  02/01/2005 Authors: Pletz MWR; McGee L; Beall B; Whitney CG; Klugman KP
• Ciprofloxacin treatment failure in a patient with resistant Streptococcus pneumoniae infection following prior ciprofloxacin therapy.
  Eur J Clin Microbiol Infect Dis Volume: 24 Page(s): 58 - 60
  01/01/2005 Authors: Pletz MWR; McGee L; Burkhardt O; Lode H; Klugman KP
• Dose response of CRM197 and tetanus toxoid-conjugated Haemophilus influenzae type b vaccines.
  Vaccine Volume: 23 Page(s): 802 - 806
  12/21/2004 Authors: Huebner RE; Nicol M; Mothupi R; Kyhty H; Mbelle N; Khomo E; Klugman KP
• Fluoroquinolone-resistant Streptococcus pneumoniae, an emerging but unrecognized public health concern: is it time to resight the goalposts?
  Clin Infect Dis Volume: 39 Page(s): 1554 - 1556
  11/15/2004 Authors: Ambrose PG; Bast D; Doern GV; Iannini PB; Jones RN; Klugman KP; Low DE
• Community-acquired pneumonia: new management strategies for evolving pathogens and antimicrobial susceptibilities.
  Int J Antimicrob Agents Volume: 24 Page(s): 411 - 422
  11/01/2004 Authors: Klugman KP; Low DE; Metlay J; Pechere J-C; Weiss K
• Failures of beta-lactam therapy for invasive pneumococcal disease.
  Pediatr Infect Dis J Volume: 23 Page(s): 980 - 981
  10/01/2004 Authors: Klugman KP
• Future trends in antimicrobial chemotherapy: expert opinion on the 43rd ICAAC.
  J Chemother Volume: 16 Page(s): 419 - 436
  10/01/2004 Authors: Ball AP; Bartlett JG; Craig WA; Drusano GL; Felmingham D; Garau JA; Klugman KP; Low DE; Mandell LA; Rubinstein E
• Oral antibiotics for the treatment of severe pneumonia in children.
  Lancet Volume: 364 Page(s): 1104 - 1105
  09/25/2004 Authors: Klugman KP; Madhi SA
• Impact of haemophilus influenzae type b conjugate vaccine in South Africa and Argentina.
  Pediatr Infect Dis J Volume: 23 Page(s): 842 - 847
  09/01/2004 Authors: Martin M; Casellas JM; Madhi SA; Urquhart TJ; Delport SD; Ferrero F; Chamany S; Dayan GH; Rose CE; Levine OS
• Vaccination: a novel approach to reduce antibiotic resistance.
  Clin Infect Dis Volume: 39 Page(s): 649 - 651
  09/01/2004 Authors: Klugman KP
• Levofloxacin-resistant invasive Streptococcus pneumoniae in the United States: evidence for clonal spread and the impact of conjugate pneumococcal vaccine.
  Antimicrob Agents Chemother Volume: 48 Page(s): 3491 - 3497
  09/01/2004 Authors: Pletz MWR; McGee L; Jorgensen J; Beall B; Facklam RR; Whitney CG; Klugman KP
• Combination antibiotic therapy lowers mortality among severely ill patients with pneumococcal bacteremia.
  Am J Respir Crit Care Med Volume: 170 Page(s): 440 - 444
  08/15/2004 Authors: Baddour LM; Yu VL; Klugman KP; Feldman C; Ortqvist A; Rello J; Morris AJ; Luna CM; Snydman DR; Ko WC
• A role for Streptococcus pneumoniae in virus-associated pneumonia.
  Nat Med Volume: 10 Page(s): 811 - 813
  08/01/2004 Authors: Madhi SA; Klugman KP; Vaccine Trialist Group
• Emergence of Streptococcus pneumoniae with very-high-level resistance to penicillin.
  Antimicrob Agents Chemother Volume: 48 Page(s): 3016 - 3023
  08/01/2004 Authors: Schrag SJ; McGee L; Whitney CG; Beall B; Craig AS; Choate ME; Jorgensen JH; Facklam RR; Klugman KP; Active Bacterial Core Surveillance Team
• Long-term antibody levels and booster responses in South African children immunized with nonavalent pneumococcal conjugate vaccine.
  Vaccine Volume: 22 Page(s): 2696 - 2700
  07/29/2004 Authors: Huebner RE; Mbelle N; Forrest B; Madore DV; Klugman KP
• Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases.
  Clin Infect Dis Volume: 39 Page(s): 31 - 37
  07/01/2004 Authors: Paterson DL; Ko W-C; Von Gottberg A; Mohapatra S; Casellas JM; Goossens H; Mulazimoglu L; Trenholme G; Klugman KP; Bonomo RA
• Gender as a risk factor for both antibiotic resistance and infection with pediatric serogroups/serotypes, in HIV-infected and -uninfected adults with pneumococcal bacteremia.
  J Infect Dis Volume: 189 Page(s): 1996 - 2000
  06/01/2004 Authors: Buie KA; Klugman KP; von Gottberg A; Perovic O; Karstaedt A; Crewe-Brown HH; Madhi SA; Feldman C
• Guidelines for empiric antimicrobial prescribing in community-acquired pneumonia.
  Chest Volume: 125 Page(s): 1888 - 1901
  05/01/2004 Authors: File TM; Garau J; Blasi F; Chidiac C; Klugman K; Lode H; Lonks JR; Mandell L; Ramirez J; Yu V
• Human metapneumovirus-associated lower respiratory tract infections among hospitalized human immunodeficiency virus type 1 (HIV-1)-infected and HIV-1-uninfected African infants (vol 37, pg 1705, 2003)
  CLINICAL INFECTIOUS DISEASES Volume: 38 Page(s): 1201 - 1201
  04/15/2004 Authors: Madhi SA; Ludewick H; Abed Y; Klugman KP; Boivin G
• Vaccines as tools against resistance: the example of pneumococcal conjugate vaccine.
  Semin Pediatr Infect Dis Volume: 15 Page(s): 86 - 93
  04/01/2004 Authors: Whitney CG; Klugman KP
• Clinical significance of Streptococcus pneumoniae resistance reporting remains confusing - Reply
  CLINICAL INFECTIOUS DISEASES Volume: 38 Page(s): 765 - 766
  03/01/2004 Authors: Yu VL; Klugman KP; Ortqvist A; Baddour LM; Rello J; Feldman C
• Clinical significance of Streptococcus pneumoniae resistance reporting remains confusing.
  Clin Infect Dis Volume: 38 Page(s): 764 - 765
  03/01/2004 Authors: Siegel RE
• International prospective study of Klebsiella pneumoniae bacteremia: implications of extended-spectrum beta-lactamase production in nosocomial Infections.
  Ann Intern Med Volume: 140 Page(s): 26 - 32
  01/06/2004 Authors: Paterson DL; Ko W-C; Von Gottberg A; Mohapatra S; Casellas JM; Goossens H; Mulazimoglu L; Trenholme G; Klugman KP; Bonomo RA
• Pneumococcal conjugate vaccine in children - Reply
  NEW ENGLAND JOURNAL OF MEDICINE Volume: 350 Page(s): 85 - 85
  01/01/2004 Authors: Klugman KP; Madhi SA; Kohberger R
• Pneumococcal conjugate vaccine in children.
  N Engl J Med Volume: 350 Page(s): 84 - 85
  01/01/2004 Authors: Davis RL; Fireman B; Shinefield HR
• The efficacy and effectiveness of pneumococcal conjugate vaccines
  Page(s): 104 - 108
  01/01/2004 Authors: Klugman KP
• Human metapneumovirus-associated lower respiratory tract infections among hospitalized human immunodeficiency virus type 1 (HIV-1)-infected and HIV-1-uninfected African infants.
  Clin Infect Dis Volume: 37 Page(s): 1705 - 1710
  12/15/2003 Authors: Madhi SA; Ludewick H; Abed Y; Klugman KP; Boivin G
• Emergence of fluoroquinolone-resistant Streptococcus pneumoniae in a South African child in a tuberculosis treatment facility.
  Pediatr Infect Dis J Volume: 22 Page(s): 1020 - 1021
  11/01/2003 Authors: von Gottberg A; Ludewick H; Bamber S; Govind C; Sturm AW; Klugman KP
• A trial of a 9-valent pneumococcal conjugate vaccine in children with and those without HIV infection.
  N Engl J Med Volume: 349 Page(s): 1341 - 1348
  10/02/2003 Authors: Klugman KP; Madhi SA; Huebner RE; Kohberger R; Mbelle N; Pierce N; Vaccine Trialists Group
• Questions regarding the effectiveness of trimethoprim-sulfamethoxazole (cotrimoxazole) prophylaxis in African children - Reply
  CLINICAL INFECTIOUS DISEASES Volume: 37 Page(s): 864 - 864
  09/15/2003 Authors: Madhi SA; Klugman KP
• Questions regarding the effectiveness of trimethoprim-sulfamethoxazole (cotrimoxazole) prophylaxis in African children.
  Clin Infect Dis Volume: 37 Page(s): 863 - 864
  09/15/2003 Authors: Gill CJ; Hamer D; Thea DM
• Susceptibility of Bacillus anthracis to eleven antimicrobial agents including novel fluoroquinolones and a ketolide.
  J Antimicrob Chemother Volume: 52 Page(s): 297 - 299
  08/01/2003 Authors: Frean J; Klugman KP; Arntzen L; Bukofzer S
• Susceptibility of Yersinia pestis to novel and conventional antimicrobial agents.
  J Antimicrob Chemother Volume: 52 Page(s): 294 - 296
  08/01/2003 Authors: Frean J; Klugman KP; Arntzen L; Bukofzer S
• The Alexander Project 1998-2000: susceptibility of pathogens isolated from community-acquired respiratory tract infection to commonly used antimicrobial agents.
  J Antimicrob Chemother Volume: 52 Page(s): 229 - 246
  08/01/2003 Authors: Jacobs MR; Felmingham D; Appelbaum PC; Grneberg RN; Alexander Project Group
• An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcome.
  Clin Infect Dis Volume: 37 Page(s): 230 - 237
  07/15/2003 Authors: Yu VL; Chiou CCC; Feldman C; Ortqvist A; Rello J; Morris AJ; Baddour LM; Luna CM; Snydman DR; Ip M
• Serological criteria for evaluation and licensure of new pneumococcal conjugate vaccine formulations for use in infants.
  Vaccine Volume: 21 Page(s): 3265 - 3272
  07/04/2003 Authors: Jdar L; Butler J; Carlone G; Dagan R; Goldblatt D; Kyhty H; Klugman K; Plikaytis B; Siber G; Kohberger R
• Antibiotic prescribing practices for common childhood illnesses in South Africa.
  S Afr Med J Volume: 93 Page(s): 505 - 508
  07/01/2003 Authors: Huebner RE; Wasas AD; Klugman KP
• Pulmonary echinococcosis.
  Eur Respir J Volume: 21 Page(s): 1069 - 1077
  06/01/2003 Authors: Morar R; Feldman C
• Antibiotic resistance and serotype distribution of Streptococcus pneumoniae colonizing rural Malawian children.
  Pediatr Infect Dis J Volume: 22 Page(s): 564 - 567
  06/01/2003 Authors: Feikin DR; Davis M; Nwanyanwu OC; Kazembe PN; Barat LM; Wasas A; Bloland PB; Ziba C; Capper T; Huebner RE
• Pneumococcal conjugate vaccines: proceedings from an interactive symposium at the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy.
  Vaccine Volume: 21 Page(s): 1562 - 1571
  04/02/2003 Authors: Pelton SI; Dagan R; Gaines BM; Klugman KP; Laufer D; O'Brien K; Schmitt HJ
• Correlation between erythromycin and azithromycin resistance in Streptococcus pneumoniae.
  S Afr Med J Volume: 93 Page(s): 283
  04/01/2003 Authors: Wasas AD; Huebner RE; Hockman M; Klugman KP
• P-carinii pneumonia in African children and the ineffectiveness of TMP-SMX prophylaxis - Reply
  CLINICAL INFECTIOUS DISEASES Volume: 36 Page(s): 939 - 940
  04/01/2003 Authors: Madhi SA; Klugman KP
• P. carinii pneumonia in African children and the ineffectiveness of TMP-SMX prophylaxis.
  Clin Infect Dis Volume: 36 Page(s): 937 - 939
  04/01/2003 Authors: Cruciani M; Malena M; Mengoli C
• The role of clonality in the global spread of fluoroquinolone-resistant bacteria.
  Clin Infect Dis Volume: 36 Page(s): 783 - 785
  03/15/2003 Authors: Klugman KP
• Implications for antimicrobial prescribing of strategies based on bacterial eradication.
  Int J Infect Dis Volume: 7 Suppl 1 Page(s): S27 - S31
  03/01/2003 Authors: Klugman KP
• Bacterial aetiology of non-resolving otitis media in South African children.
  J Laryngol Otol Volume: 117 Page(s): 169 - 172
  03/01/2003 Authors: Huebner RE; Wasas AD; Hockman M; Klugman KP; ENT Study Group
• Report from a WHO working group: standard method for detecting upper respiratory carriage of Streptococcus pneumoniae.
  Pediatr Infect Dis J Volume: 22 Page(s): 133 - 140
  02/01/2003 Authors: O'Brien KL; Nohynek H; World Health Organization Pneumococcal Vaccine Trials Carraige Working Group
• Site-specific mutagenesis analysis of PBP 1A from a penicillin-cephalosporin-resistant pneumococcal isolate.
  Antimicrob Agents Chemother Volume: 47 Page(s): 387 - 389
  01/01/2003 Authors: Smith AM; Klugman KP
• The successful clone: the vector of dissemination of resistance in Streptococcus pneumoniae.
  J Antimicrob Chemother Volume: 50 Suppl S2 Page(s): 1 - 5
  12/01/2002 Authors: Klugman KP
• Immunogenicity after one, two or three doses and impact on the antibody response to coadministered antigens of a nonavalent pneumococcal conjugate vaccine in infants of Soweto, South Africa.
  Pediatr Infect Dis J Volume: 21 Page(s): 1004 - 1007
  11/01/2002 Authors: Huebner RE; Mbelle N; Forrest B; Madore DV; Klugman KP
• Ineffectiveness of trimethoprim-sulfamethoxazole prophylaxis and the importance of bacterial and viral coinfections in African children with Pneumocystis carinii pneumonia.
  Clin Infect Dis Volume: 35 Page(s): 1120 - 1126
  11/01/2002 Authors: Madhi SA; Cutland C; Ismail K; O'Reilly C; Mancha A; Klugman KP
• The battle against emerging antibiotic resistance: should fluoroquinolones be used to treat children?
  Clin Infect Dis Volume: 35 Page(s): 721 - 727
  09/15/2002 Authors: Mandell LA; Peterson LR; Wise R; Hooper D; Low DE; Schaad UB; Klugman KP; Courvalin P
• Historical changes in pneumococcal serogroup distribution: implications for the era of pneumococcal conjugate vaccines.
  Clin Infect Dis Volume: 35 Page(s): 547 - 555
  09/01/2002 Authors: Feikin DR; Klugman KP
• Analysis of penicillin-binding protein genes of clinical isolates of Streptococcus pneumoniae with reduced susceptibility to amoxicillin.
  Antimicrob Agents Chemother Volume: 46 Page(s): 2349 - 2357
  08/01/2002 Authors: du Plessis M; Bingen E; Klugman KP
• Management of community-acquired pneumonia in adults
  SAMJ SOUTH AFRICAN MEDICAL JOURNAL Volume: 92 Page(s): 647 - 655
  08/01/2002 Authors: Feldman C; Brink AJ; Richards G; Bateman ED; O'Brien J; Maartens G; Klugman KP
• Management of community-acquired pneumonia in adults.
  S Afr Med J Volume: 92 Page(s): 647 - 655
  08/01/2002 Authors: Working Group of the South African Thoracic Society
• Bacteriological evidence of antibiotic failure in pneumococcal lower respiratory tract infections.
  Eur Respir J Suppl Volume: 36 Page(s): 3s - 8s
  07/01/2002 Authors: Klugman KP
• Severe lower respiratory tract infections associated with human parainfluenza viruses 1-3 in children infected and noninfected with HIV type 1.
  Eur J Clin Microbiol Infect Dis Volume: 21 Page(s): 499 - 505
  07/01/2002 Authors: Madhi SA; Ramasamy N; Petersen K; Madhi A; Klugman KP
• Defining the potential impact of conjugate bacterial polysaccharide-protein vaccines in reducing the burden of pneumonia in human immunodeficiency virus type 1-infected and -uninfected children.
  Pediatr Infect Dis J Volume: 21 Page(s): 393 - 399
  05/01/2002 Authors: Madhi SA; Cumin E; Klugman KP
• Reduced effectiveness of Haemophilus influenzae type b conjugate vaccine in children with a high prevalence of human immunodeficiency virus type 1 infection.
  Pediatr Infect Dis J Volume: 21 Page(s): 315 - 321
  04/01/2002 Authors: Madhi SA; Petersen K; Khoosal M; Huebner RE; Mbelle N; Mothupi R; Saloojee H; Crewe-Brown H; Klugman KP
• Lower respiratory tract infections associated with influenza A and B viruses in an area with a high prevalence of pediatric human immunodeficiency type 1 infection.
  Pediatr Infect Dis J Volume: 21 Page(s): 291 - 297
  04/01/2002 Authors: Madhi SA; Ramasamy N; Bessellar TG; Saloojee H; Klugman KP
• In vitro activity of faropenem against respiratory pathogens.
  J Antimicrob Chemother Volume: 49 Page(s): 575 - 577
  03/01/2002 Authors: du Plessis M; Capper TP; Klugman KP
• Community-acquired Klebsiella pneumoniae bacteremia: global differences in clinical patterns.
  Emerg Infect Dis Volume: 8 Page(s): 160 - 166
  02/01/2002 Authors: Ko W-C; Paterson DL; Sagnimeni AJ; Hansen DS; Von Gottberg A; Mohapatra S; Casellas JM; Goossens H; Mulazimoglu L; Trenholme G
• Haemophilus influenzae type b conjugate vaccine diluted tenfold in diphtheria-tetanus-whole cell pertussis vaccine: a randomized trial.
  Pediatr Infect Dis J Volume: 21 Page(s): 138 - 141
  02/01/2002 Authors: Nicol M; Huebner R; Mothupi R; Kyhty H; Mbelle N; Khomo E; Klugman KP
• Quinolone treatment for pediatric bacterial meningitis: a comparative study of trovafloxacin and ceftriaxone with or without vancomycin.
  Pediatr Infect Dis J Volume: 21 Page(s): 14 - 22
  01/01/2002 Authors: Sez-Llorens X; McCoig C; Feris JM; Vargas SL; Klugman KP; Hussey GD; Frenck RW; Falleiros-Carvalho LH; Arguedas AG; Bradley J
• Fluoroquinolone resistance among clinical isolates of Streptococcus pneumoniae belonging to international multiresistant clones.
  J Antimicrob Chemother Volume: 49 Page(s): 173 - 176
  01/01/2002 Authors: McGee L; Goldsmith CE; Klugman KP
• Antibiotic therapy of community respiratory tract infections: strategies for optimal outcomes and minimized resistance emergence.
  J Antimicrob Chemother Volume: 49 Page(s): 31 - 40
  01/01/2002 Authors: Ball P; Baquero F; Cars O; File T; Garau J; Klugman K; Low DE; Rubinstein E; Wise R; Consensus Group on Resistance and Prescribing in Respiratory Tract Infection
• Surveillance of resistance in bacteria causing community-acquired respiratory tract infections.
  Clin Microbiol Infect Volume: 8 Suppl 2 Page(s): 12 - 42
  01/01/2002 Authors: Felmingham D; Feldman C; Hryniewicz W; Klugman K; Kohno S; Low DE; Mendes C; Rodloff AC
• Prognostic factors in severe community-acquired pneumonia in patients without co-morbid illness.
  Respirology Volume: 6 Page(s): 323 - 330
  12/01/2001 Authors: Feldman C; Viljoen E; Morar R; Richards G; Sawyer L; Goolam Mahomed A
• Maximizing Antimicrobial Efficacy/Minimizing Antimicrobial Resistance: A Paradigm for the New Millennium - Proceedings of a Symposium held at the American Academy of Arts and Sciences, Cambridge, Massachusetts, 7-8 December 1999 - General discussion
  CLINICAL INFECTIOUS DISEASES Volume: 33 Page(s): S251 - S260
  09/15/2001 Authors: Zinner SH; Wise R; Moellering RC; Acar J; Craig W; Davey P; Garau J; Klugman K; Kristinsson K; Levin B
• Pneumococcal conjugate vaccines in Asia and the Pacific. Singapore, 9-11 October 2000. Report of an Asia Pacific Board Advisory Meeting.
  Volume: 19 Page(s): 4579 - 4587
  09/14/2001
• Emergence of a pneumococcal clone with cephalosporin resistance and penicillin susceptibility.
  Antimicrob Agents Chemother Volume: 45 Page(s): 2648 - 2650
  09/01/2001 Authors: Smith AM; Botha RF; Koornhof HJ; Klugman KP
• Efficacy of pneumococcal conjugate vaccines and their effect on carriage and antimicrobial resistance.
  Lancet Infect Dis Volume: 1 Page(s): 85 - 91
  09/01/2001 Authors: Klugman KP
• Antibiotic selection of multiply resistant pneumococci.
  Clin Infect Dis Volume: 33 Page(s): 489 - 491
  08/15/2001 Authors: Klugman KP
• Alterations in MurM, a cell wall muropeptide branching enzyme, increase high-level penicillin and cephalosporin resistance in Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 45 Page(s): 2393 - 2396
  08/01/2001 Authors: Smith AM; Klugman KP
• Nomenclature of major antimicrobial-resistant clones of Streptococcus pneumoniae defined by the pneumococcal molecular epidemiology network.
  J Clin Microbiol Volume: 39 Page(s): 2565 - 2571
  07/01/2001 Authors: McGee L; McDougal L; Zhou J; Spratt BG; Tenover FC; George R; Hakenbeck R; Hryniewicz W; Lefvre JC; Tomasz A
• Bacterial respiratory infections: closing in on antibiotic effectiveness... and ineffectiveness - Foreword
  RESPIRATORY MEDICINE Volume: 95 Page(s): S3 - S3
  06/01/2001 Authors: Klugman K; Poole MD
• Outcome of cephalosporin treatment for serious infections due to apparently susceptible organisms producing extended-spectrum beta-lactamases: implications for the clinical microbiology laboratory.
  J Clin Microbiol Volume: 39 Page(s): 2206 - 2212
  06/01/2001 Authors: Paterson DL; Ko WC; Von Gottberg A; Casellas JM; Mulazimoglu L; Klugman KP; Bonomo RA; Rice LB; McCormack JG; Yu VL
• Detection of low levels of fluoroquinolone resistance in 2340 blood and CSF isolates of Streptococcus pneumoniae in South Africa
  JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Volume: 47 Page(s): 35 - 35
  06/01/2001 Authors: Klugman K
• Ecological aspects of resistance: Spread and control
  JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Volume: 47 Page(s): 7 - 7
  06/01/2001 Authors: Klugman KP
• Serotype 19f multiresistant pneumococcal clone harboring two erythromycin resistance determinants (erm(B) and mef(A)) in South Africa.
  Antimicrob Agents Chemother Volume: 45 Page(s): 1595 - 1598
  05/01/2001 Authors: McGee L; Klugman KP; Wasas A; Capper T; Brink A
• Streptococcus pneumoniae respiratory tract infections.
  Curr Opin Infect Dis Volume: 14 Page(s): 173 - 179
  04/01/2001 Authors: Klugman KP; Feldman C
• Differing manifestations of respiratory syncytial virus-associated severe lower respiratory tract infections in human immunodeficiency virus type 1-infected and uninfected children.
  Pediatr Infect Dis J Volume: 20 Page(s): 164 - 170
  02/01/2001 Authors: Madhi SA; Venter M; Madhi A; Petersen MK; Klugman KP
• Evidence to support the rationale that bacterial eradication in respiratory tract infection is an important aim of antimicrobial therapy.
  J Antimicrob Chemother Volume: 47 Page(s): 129 - 140
  02/01/2001 Authors: Dagan R; Klugman KP; Craig WA; Baquero F
• Prevalence of serotypes and molecular epidemiology of Streptococcus pneumoniae strains isolated from children in Beijing, China: identification of two novel multiply-resistant clones.
  Microb Drug Resist Volume: 7 Page(s): 55 - 63
  01/01/2001 Authors: McGee L; Wang H; Wasas A; Huebner R; Chen M; Klugman KP
• In vitro Gram-positive antimicrobial activity of evernimicin (SCH 27899), a novel oligosaccharide, compared with other antimicrobials: a multicentre international trial.
  J Antimicrob Chemother Volume: 47 Page(s): 15 - 25
  01/01/2001 Authors: Jones RN; Hare RS; Sabatelli FJ; Ziracin Susceptibility Testing Group
• Detection of Penicillin Resistance in Streptococcus pneumoniae by a Seminested PCR Strategy.
  Methods Mol Med Volume: 48 Page(s): 65 - 75
  01/01/2001 Authors: Plessis M; Smith AM; Klugman KP
• Impact of human immunodeficiency virus type 1 infection on the epidemiology and outcome of bacterial meningitis in South African children.
  Int J Infect Dis Volume: 5 Page(s): 119 - 125
  01/01/2001 Authors: Madhi SA; Madhi A; Petersen K; Khoosal M; Klugman KP
• Impact of human immunodeficiency virus type 1 on the disease spectrum of Streptococcus pneumoniae in South African children.
  Pediatr Infect Dis J Volume: 19 Page(s): 1141 - 1147
  12/01/2000 Authors: Madhi SA; Petersen K; Madhi A; Wasas A; Klugman KP
• Evernimicin (SCH27899) inhibits a novel ribosome target site: analysis of 23S ribosomal DNA mutants.
  Antimicrob Agents Chemother Volume: 44 Page(s): 3101 - 3106
  11/01/2000 Authors: Adrian PV; Mendrick C; Loebenberg D; McNicholas P; Shaw KJ; Klugman KP; Hare RS; Black TA
• Prevalence of nasopharyngeal antibiotic-resistant pneumococcal carriage in children attending private paediatric practices in Johannesburg.
  S Afr Med J Volume: 90 Page(s): 1116 - 1121
  11/01/2000 Authors: Huebner RE; Wasas AD; Klugman KP; Paediatric Study Group
• Lack of utility of serotyping multiple colonies for detection of simultaneous nasopharyngeal carriage of different pneumococcal serotypes.
  Pediatr Infect Dis J Volume: 19 Page(s): 1017 - 1020
  10/01/2000 Authors: Huebner RE; Dagan R; Porath N; Wasas AD; Klugman KP
• In vitro activity of evernimicin and selected antibiotics against methicillin-resistant staphylococci: a 24-country study.
  Clin Microbiol Infect Volume: 6 Page(s): 549 - 556
  10/01/2000 Authors: Goering R; Nord CE; Hare R; Sabatelli F; Ziracin Susceptibility Testing Group
• Levofloxacin-resistant pneumococcus.
  Clin Infect Dis Volume: 31 Page(s): 626 - 627
  08/01/2000 Authors: Klugman KP
• Increased disease burden and antibiotic resistance of bacteria causing severe community-acquired lower respiratory tract infections in human immunodeficiency virus type 1-infected children.
  Clin Infect Dis Volume: 31 Page(s): 170 - 176
  07/01/2000 Authors: Madhi SA; Petersen K; Madhi A; Khoosal M; Klugman KP
• Increased burden of respiratory viral associated severe lower respiratory tract infections in children infected with human immunodeficiency virus type-1.
  J Pediatr Volume: 137 Page(s): 78 - 84
  07/01/2000 Authors: Madhi SA; Schoub B; Simmank K; Blackburn N; Klugman KP
• Management of community-acquired pneumonia in the era of pneumococcal resistance: a report from the Drug-Resistant Streptococcus pneumoniae Therapeutic Working Group.
  Arch Intern Med Volume: 160 Page(s): 1399 - 1408
  05/22/2000 Authors: Heffelfinger JD; Dowell SF; Jorgensen JH; Klugman KP; Mabry LR; Musher DM; Plouffe JF; Rakowsky A; Schuchat A; Whitney CG
• Novel expansions of the gene encoding dihydropteroate synthase in trimethoprim-sulfamethoxazole-resistant Streptococcus pneumoniae (vol 43, pg 2225, 1999)
  ANTIMICROBIAL AGENTS AND CHEMOTHERAPY Volume: 44 Page(s): 1411 - 1411
  05/01/2000 Authors: Padayachee T; Klugman KP
• Antimicrobial resistance of nasopharyngeal isolates of Streptococcus pneumoniae and Haemophilus influenzae from children in the Central African Republic.
  Pediatr Infect Dis J Volume: 19 Page(s): 438 - 444
  05/01/2000 Authors: Rowe AK; Deming MS; Schwartz B; Wasas A; Rolka D; Rolka H; Ndoyo J; Klugman KP
• Increased carriage of trimethoprim/sulfamethoxazole-resistant Streptococcus pneumoniae in Malawian children after treatment for malaria with sulfadoxine/pyrimethamine.
  Volume: 181 Page(s): 1501 - 1505
  04/01/2000 Authors: Feikin DR; Dowell SF; Nwanyanwu OC; Klugman KP; Kazembe PN; Barat LM; Graf C; Bloland PB; Ziba C; Huebner RE
• Epidemiology of ciprofloxacin resistance and its relationship to extended-spectrum beta-lactamase production in Klebsiella pneumoniae isolates causing bacteremia.
  Clin Infect Dis Volume: 30 Page(s): 473 - 478
  03/01/2000 Authors: Paterson DL; Mulazimoglu L; Casellas JM; Ko WC; Goossens H; Von Gottberg A; Mohapatra S; Trenholme GM; Klugman KP; McCormack JG
• Mutations in ribosomal protein L16 conferring reduced susceptibility to evernimicin (SCH27899): implications for mechanism of action.
  Antimicrob Agents Chemother Volume: 44 Page(s): 732 - 738
  03/01/2000 Authors: Adrian PV; Zhao W; Black TA; Shaw KJ; Hare RS; Klugman KP
• Acquisition of chloramphenicol resistance by the linearization and integration of the entire staphylococcal plasmid pC194 into the chromosome of Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 44 Page(s): 393 - 395
  02/01/2000 Authors: Widdowson CA; Adrian PV; Klugman KP
• New gene cassettes for trimethoprim resistance, dfr13, and Streptomycin-spectinomycin resistance, aadA4, inserted on a class 1 integron.
  Antimicrob Agents Chemother Volume: 44 Page(s): 355 - 361
  02/01/2000 Authors: Adrian PV; Thomson CJ; Klugman KP; Amyes SG
• Non-Penicillin-Binding protein mediated high-level penicillin and cephalosporin resistance in a Hungarian clone of Streptococcus pneumoniae.
  Microb Drug Resist Volume: 6 Page(s): 105 - 110
  01/01/2000 Authors: Smith AM; Klugman KP
• Analysis of penicillin-binding protein lb and 2a genes from Streptococcus pneumoniae.
  Microb Drug Resist Volume: 6 Page(s): 127 - 131
  01/01/2000 Authors: Du Plessis M; Smith AM; Klugman KP
• Trends in antimicrobial resistance and serotype distribution of blood and cerebrospinal fluid isolates of Streptococcus pneumoniae in South Africa, 1991-1998.
  Int J Infect Dis Volume: 4 Page(s): 214 - 218
  01/01/2000 Authors: Huebner RE; Wasas AD; Klugman KP
• Rationale for a hospital-based pneumococcal vaccine trial for HIV-seropositive South Africans.
  Int J Infect Dis Volume: 4 Page(s): 231 - 232
  01/01/2000 Authors: Smego RA; Genovese G; Klugman KP
• Evaluation of the Etest as a means of determining the antibiotic susceptibilities of isolates of Streptococcus pneumoniae and Haemophilus influenzae from children in the Central African Republic.
  J Antimicrob Chemother Volume: 45 Page(s): 132 - 133
  01/01/2000 Authors: Rowe AK; Schwartz B; Wasas A; Klugman KP
• Adult pneumococcal vaccination guideline. SAMA-SA Pulmonology Society Working Group.
  S Afr Med J Volume: 89 Page(s): 1222 - 1230
  11/01/1999
• Adult influenza vaccination guideline. SAMA-SA Pulmonology Society Working Group.
  S Afr Med J Volume: 89 Page(s): 1216 - 1222
  11/01/1999
• Adult influenza vaccination guideline
  SOUTH AFRICAN MEDICAL JOURNAL Volume: 89 Page(s): 1216 - 1222
  11/01/1999 Authors: Feldman C; Klugman K
• Adult pneumococcal vaccination guideline
  SOUTH AFRICAN MEDICAL JOURNAL Volume: 89 Page(s): 1222 - 1230
  11/01/1999 Authors: Feldman C; Klugman K
• Molecular basis of rifampin resistance in Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 43 Page(s): 2361 - 2365
  10/01/1999 Authors: Padayachee T; Klugman KP
• Immunogenicity and impact on nasopharyngeal carriage of a nonavalent pneumococcal conjugate vaccine.
  J Infect Dis Volume: 180 Page(s): 1171 - 1176
  10/01/1999 Authors: Mbelle N; Huebner RE; Wasas AD; Kimura A; Chang I; Klugman KP
• Laboratory surveillance for Haemophilus influenzae type B meningococcal, and pneumococcal disease. Haemophilus Surveillance Working Group.
  S Afr Med J Volume: 89 Page(s): 924 - 925
  09/01/1999 Authors: Huebner RE; Klugman KP; Matai U; Eggers R; Hussey G
• Pneumococcal conjugate vaccine--prospects for intervention in children.
  Semin Respir Infect Volume: 14 Page(s): 285 - 294
  09/01/1999 Authors: Madhi SA; Klugman KP
• Molecular mechanisms of resistance to commonly used non-betalactam drugs in Streptococcus pneumoniae.
  Semin Respir Infect Volume: 14 Page(s): 255 - 268
  09/01/1999 Authors: Widdowson CA; Klugman KP
• Novel expansions of the gene encoding dihydropteroate synthase in trimethoprim-sulfamethoxazole-resistant Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 43 Page(s): 2225 - 2230
  09/01/1999 Authors: Padayachee T; Klugman KP
• Emergence of drug resistance. Impact on bacterial meningitis.
  Infect Dis Clin North Am Volume: 13 Page(s): 637 - vii
  09/01/1999 Authors: Klugman KP; Madhi SA
• Bacteremic pneumococcal pneumonia in HIV-seropositive and HIV-seronegative adults.
  Chest Volume: 116 Page(s): 107 - 114
  07/01/1999 Authors: Feldman C; Glatthaar M; Morar R; Mahomed AG; Kaka S; Cassel M; Klugman KP
• Penicillin- and cephalosporin-resistant Streptococcus pneumoniae. Emerging treatment for an emerging problem.
  Drugs Volume: 58 Page(s): 1 - 4
  07/01/1999 Authors: Klugman KP; Feldman C
• Typhoid fever vaccines.
  Vaccine Volume: 17 Page(s): 2476 - 2478
  06/04/1999 Authors: Clemens J; Hoffman S; Ivanoff B; Klugman K; Levine MM; Neira M; Pang T
• Use of Dorset egg medium for maintenance and transport of Neisseria meningitidis and Haemophilus influenzae type b.
  J Clin Microbiol Volume: 37 Page(s): 2045 - 2046
  06/01/1999 Authors: Wasas AD; Huebner RE; Klugman KP
• Pneumococcal and Haemophilus influenzae meningitis in a children's hospital in Ethiopia: serotypes and susceptibility patterns.
  Trop Med Int Health Volume: 4 Page(s): 421 - 427
  06/01/1999 Authors: Muhe L; Klugman KP
• Application of pbp1A PCR in identification of penicillin-resistant Streptococcus pneumoniae.
  J Clin Microbiol Volume: 37 Page(s): 628 - 632
  03/01/1999 Authors: du Plessis M; Smith AM; Klugman KP
• Aeromonas species isolated from medicinal leeches.
  Ann Plast Surg Volume: 42 Page(s): 275 - 279
  03/01/1999 Authors: Mackay DR; Manders EK; Saggers GC; Banducci DR; Prinsloo J; Klugman K
• The presence and sequence of endotracheal tube colonization in patients undergoing mechanical ventilation.
  Eur Respir J Volume: 13 Page(s): 546 - 551
  03/01/1999 Authors: Feldman C; Kassel M; Cantrell J; Kaka S; Morar R; Goolam Mahomed A; Philips JI
• Persistence of antibodies to the Salmonella typhi Vi capsular polysaccharide vaccine in South African school children ten years after immunization.
  Vaccine Volume: 17 Page(s): 110 - 113
  01/01/1999 Authors: Keddy KH; Klugman KP; Hansford CF; Blondeau C; Bouveret le Cam NN
• Increased activity of 16-membered lactone ring macrolides against erythromycin-resistant Streptococcus pyogenes and Streptococcus pneumoniae: characterization of South African isolates.
  J Antimicrob Chemother Volume: 42 Page(s): 729 - 734
  12/01/1998 Authors: Klugman KP; Capper T; Widdowson CA; Koornhof HJ; Moser W
• The impact of HIV on Streptococcus pneumoniae bacteraemia in a South African population.
  AIDS Volume: 12 Page(s): 2177 - 2184
  11/12/1998 Authors: Jones N; Huebner R; Khoosal M; Crewe-Brown H; Klugman K
• Antibiotic susceptibility patterns of Streptococcus pneumoniae in china and comparison of MICs by agar dilution and E-test methods.
  Antimicrob Agents Chemother Volume: 42 Page(s): 2633 - 2636
  10/01/1998 Authors: Wang H; Huebner R; Chen M; Klugman K
• Serotypes and antibacterial susceptibility of pneumococci isolated from children with infections in Ankara in relation to proposed pneumococcal vaccine coverage.
  Acta Paediatr Jpn Volume: 40 Page(s): 437 - 440
  10/01/1998 Authors: Kanra G; Erdem G; Ceyhan M; Klugman KP; Vasas A
• Pharmacokinetic profiles of high-dose intravenous ciprofloxacin in severe sepsis. The Baragwanath Ciprofloxacin Study Group.
  Antimicrob Agents Chemother Volume: 42 Page(s): 2235 - 2239
  09/01/1998 Authors: Lipman J; Scribante J; Gous AG; Hon H; Tshukutsoane S
• New trimethoprim-resistant dihydrofolate reductase cassette, dfrXV, inserted in a class 1 integron.
  Antimicrob Agents Chemother Volume: 42 Page(s): 2221 - 2224
  09/01/1998 Authors: Adrian PV; DU Plessis M; Klugman KP; Amyes SG
• Trends in beta-lactam resistance among enterobacteriaceae - Discussion
  CLINICAL INFECTIOUS DISEASES Volume: 27 Page(s): S107 - S110
  08/01/1998 Authors: Verhoef J; Proctor R; Baquero F; Acar J; Quinn J; French G; Moellering R; Drusano G; Klugman K; Bush K
• Guidelines for the management of chronic obstructive pulmonary disease. Working Group of the South African Pulmonology Society.
  S Afr Med J Volume: 88 Page(s): 999 - 1010
  08/01/1998
• Consequences of increasing resistance to antimicrobial agents - Discussion
  CLINICAL INFECTIOUS DISEASES Volume: 27 Page(s): S131 - S134
  08/01/1998 Authors: Bush K; Drusano G; Hooper D; Moellering R; Klugman K; Baquero F; Phillips I; Quinn J; Acar J; French G
• Current MIC breakpoints may understate the potential efficacies of carbapenems for treatment of patients with infections caused by strains of Streptococcus pneumoniae that are resistant or of intermediate susceptibility to penicillin.
  J Antimicrob Chemother Volume: 42 Page(s): 265 - 266
  08/01/1998 Authors: Edwards JR; Bradley JS; Klugman KP
• Genes and spectrum: The theoretical limits - Discussion
  CLINICAL INFECTIOUS DISEASES Volume: 27 Page(s): S29 - S31
  08/01/1998 Authors: Hancock R; Baquero F; Phillips I; Wiedemann B; Verhoef J; Klugman K; Acar J; Maiden M; Amyes S; Bush K
• Pneumococcal molecular epidemiology network
  ASM NEWS Volume: 64 Page(s): 371 - 371
  07/01/1998 Authors: Klugman K
• Alterations in PBP 1A essential-for high-level penicillin resistance in Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 42 Page(s): 1329 - 1333
  06/01/1998 Authors: Smith AM; Klugman KP
• Acquisition, carriage, and transmission of pneumococci with decreased antibiotic susceptibility in young children attending a day care facility in southern Israel.
  J Infect Dis Volume: 177 Page(s): 1003 - 1012
  04/01/1998 Authors: Yagupsky P; Porat N; Fraser D; Prajgrod F; Merires M; McGee L; Klugman KP; Dagan R
• Long-term survival of Streptococcus pneumoniae at room temperature on Dorset egg medium.
  J Clin Microbiol Volume: 36 Page(s): 1139 - 1140
  04/01/1998 Authors: Wasas AD; Huebner RE; De Blanche M; Klugman KP
• Rapid detection of penicillin-resistant Streptococcus pneumoniae in cerebrospinal fluid by a seminested-PCR strategy.
  J Clin Microbiol Volume: 36 Page(s): 453 - 457
  02/01/1998 Authors: du Plessis M; Smith AM; Klugman KP
• The molecular mechanisms of tetracycline resistance in the pneumococcus.
  Microb Drug Resist Volume: 4 Page(s): 79 - 84
  01/01/1998 Authors: Widdowson CA; Klugman KP
• Emergence of the M phenotype of erythromycin-resistant pneumococci in South Africa.
  Emerg Infect Dis Volume: 4 Page(s): 277 - 281
  01/01/1998 Authors: Widdowson CA; Klugman KP
• Efficacy of Vi polysaccharide vaccine against strains of Salmonella typhi: reply.
  Vaccine Volume: 16 Page(s): 871 - 872
  01/01/1998 Authors: Keddy KH; Klugman KP; Robbins JB
• Pneumococcal diseases.
  Methods Mol Med Volume: 15 Page(s): 139 - 156
  01/01/1998 Authors: Smith AM; Klugman KP
• Antibiotic resistance of nasopharyngeal isolates of Streptococcus pneumoniae from children in Lesotho.
  Bull World Health Organ Volume: 76 Page(s): 641 - 650
  01/01/1998 Authors: Mthwalo M; Wasas A; Huebner R; Koornhof HJ; Klugman KP
• Emerging infectious diseases--South Africa.
  Emerg Infect Dis Volume: 4 Page(s): 517 - 520
  01/01/1998 Authors: Klugman KP
• Nasopharyngeal carriage and antimicrobial resistance in isolates of Streptococcus pneumoniae and Haemophilus influenzae type b in children under 5 years of age in Botswana.
  Int J Infect Dis Volume: 3 Page(s): 18 - 25
  01/01/1998 Authors: Huebner RE; Wasas A; Mushi A; Mazhani L; Klugman K
• Concentration-dependent killing of antibiotic-resistant pneumococci by the methoxyquinolone moxifloxacin.
  J Antimicrob Chemother Volume: 40 Page(s): 797 - 802
  12/01/1997 Authors: Klugman KP; Capper T
• Ethics of research involving vulnerable groups.
  S Afr Med J Volume: 87 Page(s): 1667 - 1668
  12/01/1997 Authors: London L; Hoffman M; Shungking M; Midgley A; Myers J; de Pinho H; Cooper D; Morar R; Makan B; Mohamed H
• Streptococcus pneumoniae blood culture isolates from patients with and without human immunodeficiency virus infection: alterations in penicillin susceptibilities and in serogroups or serotypes.
  Clin Infect Dis Volume: 25 Page(s): 1165 - 1172
  11/01/1997 Authors: Crewe-Brown HH; Karstaedt AS; Saunders GL; Khoosal M; Jones N; Wasas A; Klugman KP
• Mutations in the dihydrofolate reductase gene of trimethoprim-resistant isolates of Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 41 Page(s): 2406 - 2413
  11/01/1997 Authors: Adrian PV; Klugman KP
• Penicillin-resistant pneumococcal meningitis.
  Lancet Volume: 350 Page(s): 1176 - 1177
  10/18/1997 Authors: Klugman KP; Koornhof HJ
• Trovafloxacin - A viewpoint
  DRUGS Volume: 54 Page(s): 446 - 446
  09/01/1997 Authors: Klugman KP
• Epidemic Shigella dysentery in South Africa.
  S Afr Med J Volume: 87 Page(s): 1145 - 1146
  09/01/1997 Authors: Klugman KP; MacPhail AP
• Trovafloxacin : A Viewpoint by Keith P. Klugman.
  Drugs Volume: 54 Page(s): 446
  09/01/1997 Authors: Klugman KP
• Cerebrospinal fluid bactericidal activity against cephalosporin-resistant Streptococcus pneumoniae in children with meningitis treated with high-dosage cefotaxime.
  Antimicrob Agents Chemother Volume: 41 Page(s): 1888 - 1891
  09/01/1997 Authors: Friedland IR; Klugman KP
• Impact of antimicrobial resistance and antibiotic choice on the outcome of pneumococcal meningitis.
  S Afr Med J Volume: 87 Page(s): 912
  07/01/1997 Authors: Klugman KP
• International quality control of phage typing of Staphylococcus aureus. International Union of Microbial Societies Subcommittee.
  J Med Microbiol Volume: 46 Page(s): 511 - 516
  06/01/1997 Authors: Marples RR; Rosdahl VT
• In-vitro and in-vivo activity of trovafloxacin against Streptococcus pneumoniae.
  J Antimicrob Chemother Volume: 39 Suppl B Page(s): 51 - 55
  06/01/1997 Authors: Klugman KP; Gootz TD
• Evolution of extended spectrum cephalosporin resistance in the pneumococcus.
  J Antimicrob Chemother Volume: 39 Page(s): 837 - 838
  06/01/1997 Authors: Koornhof HJ; Klugman KP
• Exposures to Legionella pneumophila and Chlamydia pneumoniae in South African Mine Workers.
  Int J Occup Environ Health Volume: 3 Page(s): 120 - 127
  04/01/1997 Authors: Bartie C; Klugman KP
• "Megaprimer" method of PCR-based mutagenesis: the concentration of megaprimer is a critical factor.
  Biotechniques Volume: 22 Page(s): 438 - 442
  03/01/1997 Authors: Smith AM; Klugman KP
• Antibiotic resistance among nasopharyngeal isolates of Streptococcus pneumoniae and Haemophilus influenzae - Bangui, 1995 (Reprinted from MMWR, vol 46, pg 62-64, 1997)
  JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION Volume: 277 Page(s): 621 - 621
  02/26/1997 Authors: Ndoyo J; Siopathis RM; Klugman KP; Wasas A
• Pneumococcal resistance - the challenge of childhood infection
  Volume: 19 Page(s): 9 - 18
  01/01/1997 Authors: Klugman KP
• The most frequent aminoglycoside resistance mechanisms--changes with time and geographic area: a reflection of aminoglycoside usage patterns? Aminoglycoside Resistance Study Groups.
  Volume: 24 Suppl 1 Page(s): S46 - S62
  01/01/1997 Authors: Miller GH; Sabatelli FJ; Hare RS; Glupczynski Y; Mackey P; Shlaes D; Shimizu K; Shaw KJ
• Penetration of cefpodoxime into middle ear fluid in pediatric patients with acute otitis media.
  Pediatr Infect Dis J Volume: 16 Page(s): 79 - 81
  01/01/1997 Authors: van Dyk JC; Terespolsky SA; Meyer CS; van Niekerk CH; Klugman KP
• Three predominant clones identified within penicillin-resistant South African isolates of Streptococcus pneumoniae.
  Microb Drug Resist Volume: 3 Page(s): 385 - 389
  01/01/1997 Authors: Smith AM; Klugman KP
• Spread of the Spanish multi-resistant serotype 23F clone of Streptococcus pneumoniae to Seoul, Korea.
  Microb Drug Resist Volume: 3 Page(s): 253 - 257
  01/01/1997 Authors: McGee L; Klugman KP; Friedland D; Lee HJ
• Nasopharyngeal carriage of community-acquired, antibiotic-resistant Streptococcus pneumoniae in a Zambian paediatric population.
  Bull World Health Organ Volume: 75 Page(s): 453 - 462
  01/01/1997 Authors: Woolfson A; Huebner R; Wasas A; Chola S; Godfrey-Faussett P; Klugman K
• In vitro susceptibility of penicillin-resistant Streptococcus pneumoniae to levofloxacin, selection of resistant mutants, and time-kill synergy studies of levofloxacin combined with vancomycin, teicoplanin, fusidic acid, and rifampin.
  Antimicrob Agents Chemother Volume: 40 Page(s): 2802 - 2804
  12/01/1996 Authors: Klugman KP; Capper T; Bryskier A
• Identification of the tetracycline resistance gene, tet(O), in Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 40 Page(s): 2891 - 2893
  12/01/1996 Authors: Widdowson CA; Klugman KP; Hanslo D
• In vitro activities of 14 antibiotics against 100 human isolates of Yersinia pestis from a southern African plague focus.
  Antimicrob Agents Chemother Volume: 40 Page(s): 2646 - 2647
  11/01/1996 Authors: Frean JA; Arntzen L; Capper T; Bryskier A; Klugman KP
• Incidence of high-level gentamicin resistance in enterococci at Johannesburg Hospital.
  S Afr Med J Volume: 86 Page(s): 1273 - 1276
  10/01/1996 Authors: Keddy KH; Klugman KP; Liebowitz LD
• Comparative in vitro activity of piperacillin/tazobactam against gram-negative bacilli.
  S Afr Med J Volume: 86 Page(s): 1276 - 1280
  10/01/1996 Authors: Liebowitz LD; Klugman KP
• Management of community-acquired pneumonia in adults. Working groups of the South African Pulmonology Society and the Antibiotic Study Group of South Africa.
  S Afr Med J Volume: 86 Page(s): 1152 - 1163
  09/01/1996
• Efficacy, safety and tolerability of meropenem as empiric antibiotic therapy in hospitalized pediatric patients.
  Volume: 15 Page(s): 749 - 757
  08/01/1996 Authors: Bradley JS; Faulkner KL; Klaugman KP
• The clinical relevance of in-vitro resistance to penicillin, ampicillin, amoxycillin and alternative agents, for the treatment of community-acquired pneumonia caused by Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis.
  J Antimicrob Chemother Volume: 38 Suppl A Page(s): 133 - 140
  07/01/1996 Authors: Klugman KP
• IgG subclasses in previously healthy adult patients with acute community-acquired pneumonia.
  S Afr Med J Volume: 86 Page(s): 600 - 602
  05/01/1996 Authors: Feldman C; Mahomed AG; Mahida P; Morar R; Schoeman A; Mpe J; Burgin S; Kuschke RH; Wadee A
• Immunogenicity, efficacy and serological correlate of protection of Salmonella typhi Vi capsular polysaccharide vaccine three years after immunization.
  Vaccine Volume: 14 Page(s): 435 - 438
  04/01/1996 Authors: Klugman KP; Koornhof HJ; Robbins JB; Le Cam NN
• Cryptococcosis: an unusual cause of endobronchial obstruction.
  Eur Respir J Volume: 9 Page(s): 837 - 839
  04/01/1996 Authors: Mahida P; Morar R; Goolam Mahomed A; Song E; Tissandie JP; Feldman C
• Epidemiology, control and treatment of multiresistant pneumococci.
  Drugs Volume: 52 Suppl 2 Page(s): 42 - 46
  01/01/1996 Authors: Klugman KP
• Antibiotic-resistant pneumococcal pneumonia.
  S Afr Med J Volume: 86 Page(s): 28 - 30
  01/01/1996 Authors: Feldman C; Klugman K
• Epidemiology, control and treatment of multidrug-resistant tuberculosis - Discussion
  DRUGS Volume: 52 Page(s): 107 - 108
  01/01/1996 Authors: Finch RG; Chaulet P; Klugman KP
• Epidemiology, control and treatment of multiresistant pneumococci - Discussion
  DRUGS Volume: 52 Page(s): 46 - 46
  01/01/1996 Authors: Mukhtar AH; Klugman KP; Schaad UB
• Epidemiology and control of multiresistant enterococci - Discussion
  DRUGS Volume: 52 Page(s): 49 - 49
  01/01/1996 Authors: Mukhtar AH; Leclercq R; Hoiby N; Klugman KP
• New concepts in the pathophysiology and management of middle ear disease in childhood - Discussion
  DRUGS Volume: 52 Page(s): 66 - 67
  01/01/1996 Authors: Kungu C; Pelton SI; Glauser MP; Klugman KP; Gnehm HE
• Consensus: management of infections in children caused by Streptococcus pneumoniae with decreased susceptibility to penicillin.
  Pediatr Infect Dis J Volume: 14 Page(s): 1037 - 1041
  12/01/1995 Authors: Bradley JS; Kaplan SL; Klugman KP; Leggiadro RJ
• In-vitro activity of the fluoroquinolone trovafloxacin against penicillin-susceptible and -resistant Streptococcus pneumoniae.
  J Antimicrob Chemother Volume: 36 Page(s): 873 - 874
  11/01/1995 Authors: Klugman K; Wasas A
• Prevalence and genetic location of non-transferable trimethoprim resistant dihydrofolate reductase genes in South African commensal faecal isolates.
  Epidemiol Infect Volume: 115 Page(s): 255 - 267
  10/01/1995 Authors: Adrian PV; Thomson CJ; Klugman KP; Amyes SG
• Bactericidal activity against cephalosporin-resistant Streptococcus pneumoniae in cerebrospinal fluid of children with acute bacterial meningitis.
  Antimicrob Agents Chemother Volume: 39 Page(s): 1988 - 1992
  09/01/1995 Authors: Klugman KP; Friedland IR; Bradley JS
• Potential interventions for the prevention of childhood pneumonia: geographic and temporal differences in serotype and serogroup distribution of sterile site pneumococcal isolates from children--implications for vaccine strategies.
  Pediatr Infect Dis J Volume: 14 Page(s): 503 - 510
  06/01/1995 Authors: Sniadack DH; Schwartz B; Lipman H; Bogaerts J; Butler JC; Dagan R; Echaniz-Aviles G; Lloyd-Evans N; Fenoll A; Girgis NI
• Randomized comparison of meropenem with cefotaxime for treatment of bacterial meningitis. Meropenem Meningitis Study Group.
  Antimicrob Agents Chemother Volume: 39 Page(s): 1140 - 1146
  05/01/1995 Authors: Klugman KP; Dagan R
• Prevalence of trimethoprim resistant dihydrofolate reductase genes identified with oligonucleotide probes in plasmids from isolates of commensal faecal flora.
  J Antimicrob Chemother Volume: 35 Page(s): 497 - 508
  04/01/1995 Authors: Adrian PV; Klugman KP; Amyes SG
• Alterations in penicillin-binding protein 2B from penicillin-resistant wild-type strains of Streptococcus pneumoniae.
  Antimicrob Agents Chemother Volume: 39 Page(s): 859 - 867
  04/01/1995 Authors: Smith AM; Klugman KP
• Community-acquired pneumonia in the ICU.
  Chest Volume: 107 Page(s): 1182 - 1183
  04/01/1995 Authors: Feldman C; Mohomed AG; Morar R; Mahida P
• Carbapenem treatment of meningitis.
  Scand J Infect Dis Suppl Volume: 96 Page(s): 45 - 48
  01/01/1995 Authors: Klugman KP; Dagan R
• Antibiotic-resistant pneumococci in pediatric disease.
  Microb Drug Resist Volume: 1 Page(s): 5 - 8
  01/01/1995 Authors: Klugman KP; Friedland IR
• Invasive candidiasis in the ICU--pathogenesis and management strategy.
  S Afr J Surg Volume: 32 Page(s): 154 - 156
  12/01/1994 Authors: Saunders GL; Lipman J; Klugman K
• 'Atypical' bacteria are a common cause of community-acquired pneumonia in hospitalised adults.
  S Afr Med J Volume: 84 Page(s): 678 - 682
  10/01/1994 Authors: Maartens G; Lewis SJ; de Goveia C; Bartie C; Roditi D; Klugman KP
• Actinobacillus (Pasteurella) ureae meningitis in a HIV-positive patient.
  Diagn Microbiol Infect Dis Volume: 20 Page(s): 105 - 107
  10/01/1994 Authors: Kaka S; Lunz R; Klugman KP
• Neonatal typhoid fever.
  Pediatr Infect Dis J Volume: 13 Page(s): 774 - 777
  09/01/1994 Authors: Reed RP; Klugman KP
• Increasing prevalence of penicillin-resistant pneumococcal infections in children in southern Israel: implications for future immunization policies.
  Pediatr Infect Dis J Volume: 13 Page(s): 782 - 786
  09/01/1994 Authors: Dagan R; Yagupsky P; Goldbart A; Wasas A; Klugman K
• Management of antibiotic-resistant pneumococcal infections.
  J Antimicrob Chemother Volume: 34 Page(s): 191 - 193
  08/01/1994 Authors: Klugman KP
• Haemolytic-uraemic syndrome in adults with resistant Shigella dysenteriae type I.
  Lancet Volume: 344 Page(s): 206
  07/16/1994 Authors: Bloom PD; MacPhail AP; Klugman K; Louw M; Raubenheimer C; Fischer C
• Penetration of meropenem into the cerebrospinal fluid of patients with inflamed meninges.
  J Antimicrob Chemother Volume: 34 Page(s): 175 - 179
  07/01/1994 Authors: Dagan R; Velghe L; Rodda JL; Klugman KP
• Pneumococcal resistance to the third-generation cephalosporins: clinical, laboratory and molecular aspects.
  Int J Antimicrob Agents Volume: 4 Page(s): 63 - 67
  03/01/1994 Authors: Klugman KP
• Cluster of an erythromycin-resistant variant of the Spanish multiply resistant 23F clone of Streptococcus pneumoniae in South Africa.
  Eur J Clin Microbiol Infect Dis Volume: 13 Page(s): 171 - 174
  02/01/1994 Authors: Klugman KP; Coffey TJ; Smith A; Wasas A; Meyers M; Spratt BG
• Activity of teicoplanin and vancomycin against penicillin-resistant pneumococci.
  Eur J Clin Microbiol Infect Dis Volume: 13 Page(s): 1 - 2
  01/01/1994 Authors: Klugman KP
• Control of methicillin-resistant Staphylococcus aureus bacteraemia in high-risk areas.
  Eur J Clin Microbiol Infect Dis Volume: 13 Page(s): 82 - 85
  01/01/1994 Authors: Blumberg LH; Klugman KP
• Centres of excellence for academic medicine in South Africa.
  S Afr Med J Volume: 84 Page(s): 44
  01/01/1994 Authors: Klugman KP
• REALITY REVISITED + THOUGHTS ON COMPILING AN ESSAY ON DISNEY-WORLD
  SOUTH ATLANTIC QUARTERLY Volume: 92 Page(s): 7 - 25
  12/01/1993 Authors: KLUGMAN K
• National strategy for serological diagnosis of HIV infection. Subcommittee of the AIDS Advisory Group on Strategies for HIV Testing.
  S Afr Med J Volume: 83 Page(s): 685 - 687
  09/01/1993 Authors: Fleming AF; Martin DJ
• Genetic diversity of penicillin-binding protein 2B and 2X genes from Streptococcus pneumoniae in South Africa.
  Antimicrob Agents Chemother Volume: 37 Page(s): 1938 - 1944
  09/01/1993 Authors: Smith AM; Klugman KP; Coffey TJ; Spratt BG
• In-vitro activity of cefepime against bacterial pathogens from hospitalized patients.
  J Antimicrob Chemother Volume: 32 Page(s): 164 - 166
  07/01/1993 Authors: Klugman KP; Saunders J; Khoosal M
• Pneumococci resistant to extended-spectrum cephalosporins in South Africa.
  Lancet Volume: 341 Page(s): 1164
  05/01/1993 Authors: Klugman KP; Saunders J
• Implications of bacterial resistance for the use of beta-lactam agents in clinical practice.
  S Afr Med J Volume: 83 Page(s): 163 - 164
  03/01/1993 Authors: Richards GA; Klugman KP
• Corynebacterium group D2 urinary tract infection.
  S Afr Med J Volume: 83 Page(s): 95 - 96
  02/01/1993 Authors: Stewart RG; Nowbath V; Carmichael M; Klugman KP
• Urinary tract infection with Corynebacterium urealyticum in South Africa.
  Eur J Clin Microbiol Infect Dis Volume: 12 Page(s): 18 - 24
  01/01/1993 Authors: Walkden D; Klugman KP; Vally S; Naidoo P
• Antibiotic resistance in pneumococcal meningitis.
  Lancet Volume: 340 Page(s): 437 - 438
  08/15/1992 Authors: Klugman KP; Koornhof HJ; Friedland IR
• Antibiotic-resistant pneumococcal disease in South African children.
  Am J Dis Child Volume: 146 Page(s): 920 - 923
  08/01/1992 Authors: Friedland IR; Klugman KP
• AIDS--the Baragwanath experience. Part I. Epidemiology of HIV infection at Baragwanath Hospital, 1988-1990.
  S Afr Med J Volume: 82 Page(s): 86 - 90
  08/01/1992 Authors: Friedland IR; Klugman KP; Karstaedt AS; Patel J; McIntyre JA; Allwood CW
• Increased resistance to amikacin in a neonatal unit following intensive amikacin usage.
  Antimicrob Agents Chemother Volume: 36 Page(s): 1596 - 1600
  08/01/1992 Authors: Friedland IR; Funk E; Khoosal M; Klugman KP
• Antimicrobial resistance in Streptococcus pneumoniae: a South African perspective.
  Clin Infect Dis Volume: 15 Page(s): 84 - 94
  07/01/1992 Authors: Koornhof HJ; Wasas A; Klugman K
• Epidemiology of HIV infection in pregnant women.
  Nurs RSA Volume: 7 Page(s): 39
  05/01/1992 Authors: Klugman KP
• Advances in the management of penicillin-resistant pneumococcal meningitis.
  S Afr Med J Volume: 81 Page(s): 341 - 342
  04/04/1992 Authors: Friedland IR; Klugman KP
• Failure of chloramphenicol therapy in penicillin-resistant pneumococcal meningitis.
  Lancet Volume: 339 Page(s): 405 - 408
  02/15/1992 Authors: Friedland IR; Klugman KP
• Serological markers of sexually transmitted diseases associated with HIV-1 infection in pregnant black women.
  S Afr Med J Volume: 80 Page(s): 243 - 244
  09/07/1991 Authors: Klugman KP; Patel J; Sischy A; McIntyre JA
• Recurrent penicillin-resistant pneumococcal meningitis after chloramphenicol therapy.
  Pediatr Infect Dis J Volume: 10 Page(s): 705 - 707
  09/01/1991 Authors: Friedland IR; Klugman KP
• An evaluation of two indirect fluorescent antibody tests for the diagnosis of Legionnaire's disease in South Africa.
  S Afr Med J Volume: 77 Page(s): 392 - 395
  04/21/1990 Authors: Ratshikhopha ME; Klugman KP; Koornhof HJ
• Pneumococcal resistance to antibiotics.
  Clin Microbiol Rev Volume: 3 Page(s): 171 - 196
  04/01/1990 Authors: Klugman KP
• Colony morphology of piliated Neisseria meningitidis.
  J Exp Med Volume: 170 Page(s): 1727 - 1736
  11/01/1989 Authors: Blake MS; MacDonald CM; Klugman KP
• Serotype and antimicrobial susceptibility patterns of Haemophilus influenzae isolates from inpatients and outpatients in Johannesburg.
  S Afr Med J Volume: 76 Page(s): 325 - 328
  10/07/1989 Authors: Liebowitz LD; Klugman KP; Saunders J; Koornhof HJ
• Worldwide increase in pneumococcal antibiotic resistance.
  Lancet Volume: 2 Page(s): 444
  08/19/1989 Authors: Klugman KP; Koornhof HJ
• Sequence of the structural gene (rmpM) for the class 4 outer membrane protein of Neisseria meningitidis, homology of the protein to gonococcal protein III and Escherichia coli OmpA, and construction of meningococcal strains that lack class 4 protein.
  Infect Immun Volume: 57 Page(s): 2066 - 2071
  07/01/1989 Authors: Klugman KP; Gotschlich EC; Blake MS
• NEISSERIA-MENINGITIDIS STRAINS LACKING OUTER-MEMBRANE PROTEIN CLASS-4
  CLINICAL RESEARCH Volume: 37 Page(s): A565 - A565
  04/01/1989 Authors: KLUGMAN KP; GOTSCHLICH EC; BLAKE MS
• Drug resistance patterns and serogroups or serotypes of pneumococcal isolates from cerebrospinal fluid or blood, 1979-1986.
  J Infect Dis Volume: 158 Page(s): 956 - 964
  11/01/1988 Authors: Klugman KP; Koornhof HJ
• Septic arthritis due to Cryptococcus neoformans.
  J Infect Volume: 17 Page(s): 139 - 145
  09/01/1988 Authors: Stead KJ; Klugman KP; Painter ML; Koornhof HJ
• Fatal infection caused by a multiply resistant type 3 pneumococcus.
  J Clin Microbiol Volume: 26 Page(s): 1590 - 1591
  08/01/1988 Authors: Lawrenson JB; Klugman KP; Eidelman JI; Wasas A; Miller SD; Lipman J
• CAMPYLOBACTER PYLORIDIS IN URBAN BLACKS - SIGNIFICANT
  SOUTH AFRICAN MEDICAL JOURNAL Volume: 73 Page(s): 673 - 673
  06/04/1988 Authors: ZIADY N; BUKOFZER S; LEE G; CARRIM A; SACKS A; WHITE J; KLUGMAN K; MACEROLO P
• UNUSUAL MULTIPLY RESISTANT PNEUMOCOCCI - REPLY
  AMERICAN JOURNAL OF DISEASES OF CHILDREN Volume: 142 Page(s): 254 - 254
  03/01/1988 Authors: KLUGMAN KP; KOORNHOF HJ; KUHNLE V
• Disk susceptibility testing of penicillin-resistant pneumococci.
  J Clin Microbiol Volume: 26 Page(s): 610 - 611
  03/01/1988 Authors: Klugman KP; Koornhof HJ
• CARRIAGE OF PENICILLIN RESISTANT PNEUMOCOCCI - COMMENT
  ARCHIVES OF DISEASE IN CHILDHOOD Volume: 63 Page(s): 341 - 341
  03/01/1988 Authors: KLUGMAN KP; KOORNHOF HJ
• Bacteremic pneumonia caused by penicillin-resistant pneumococci.
  N Engl J Med Volume: 318 Page(s): 123 - 124
  01/14/1988 Authors: Klugman KP; Koornhof H
• Protective activity of Vi capsular polysaccharide vaccine against typhoid fever.
  Lancet Volume: 2 Page(s): 1165 - 1169
  11/21/1987 Authors: Klugman KP; Gilbertson IT; Koornhof HJ; Robbins JB; Schneerson R; Schulz D; Cadoz M; Armand J
• Community-acquired pneumonia in an adult due to a multiply-resistant pneumococcus.
  J Infect Volume: 14 Page(s): 188 - 189
  03/01/1987 Authors: Sacho H; Klugman KP; Koornhof HJ; Ruff P
• Infection of the human orbit by Aspergillus stromatoides. Case report.
  Mycopathologia Volume: 97 Page(s): 97 - 99
  02/01/1987 Authors: Sacho H; Stead KJ; Klugman KP; Lawrence Z
• Clinical and nasopharyngeal isolates of unusual multiply resistant pneumococci.
  Am J Dis Child Volume: 140 Page(s): 1186 - 1190
  11/01/1986 Authors: Klugman KP; Koornhof HJ; Kuhnle V
• Bacterial enteritis of infancy and childhood in Soweto.
  S Afr Med J Volume: Suppl Page(s): 50 - 54
  10/11/1986 Authors: Koornhof HJ; Schoub BD; Turnbull PC; Miliotis MD; Richardson JL; Klugman KP; Khumalo Z
• Carriage of penicillin resistant pneumococci.
  Arch Dis Child Volume: 61 Page(s): 377 - 381
  04/01/1986 Authors: Klugman KP; Koornhof HJ; Wasas A; Storey K; Gilbertson I
• Meningitis and pneumonia due to novel multiply resistant pneumococci.
  Br Med J (Clin Res Ed) Volume: 292 Page(s): 730
  03/15/1986 Authors: Klugman KP; Koornhof HJ; Kuhnle V; Miller SD; Ginsburg PJ; Mauff AC
• Wound colonization by Ewingella americana.
  J Clin Microbiol Volume: 23 Page(s): 650 - 651
  03/01/1986 Authors: Bear N; Klugman KP; Tobiansky L; Koornhof HJ
• NEW TRENDS IN THE DEVELOPMENT OF BACTERIAL VACCINES
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 81 Page(s): 164 - 166
  01/01/1985 Authors: KLUGMAN KP
• Effects of haemorrhage on colloid osmotic pressure in the pigeon.
  Comp Biochem Physiol A Comp Physiol Volume: 71 Page(s): 337 - 339
  01/01/1982 Authors: Cornelius ST; Klugman KP; Hattingh J
• PERIVASCULAR INJECTIONS OF DOPAMINE CAUSE VASOCONSTRICTION OF CEREBRAL BLOOD-VESSELS
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 78 Page(s): 81 - 81
  01/01/1982 Authors: MARKOWITZ S; MITCHELL G; KLUGMAN KP; ROSENDORFF C
• NEW PERSPECTIVES ON BLOOD-FLOW TO THE BRAIN
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 78 Page(s): 3 - 3
  01/01/1982 Authors: KLUGMAN KP
• THE INTRACEREBRAL NORADRENERGIC PATHWAY AND HYPOTHALAMIC BLOOD-FLOW
  DEVELOPMENTS IN NEUROSCIENCE Volume: 14 Page(s): 537 - 549
  01/01/1982 Authors: KLUGMAN KP; MITCHELL G; ROSENDORFF C
• Body mass and sex as determining factors in the development of fever in rats.
  J Physiol Volume: 304 Page(s): 43 - 50
  07/01/1980 Authors: Ford DM; Klugman KP
• Contrasting roles of 5-hydroxytryptamine and noradrenaline in fever in rats.
  J Physiol Volume: 304 Page(s): 51 - 57
  07/01/1980 Authors: Ford DM; Klugman KP
• Lifelong antihypertensive therapy.
  S Afr Med J Volume: 57 Page(s): 851
  05/24/1980 Authors: Klugman KP; Palmer J; Schultz E
• Cholinergic regulation of intracerebral noradrenergic pathway-induced hypothalamic vasodilatation.
  Stroke Volume: 11 Page(s): 522 - 527
  01/01/1980 Authors: Klugman KP; Mitchell G; Rosendorff C
• Substance P increases hypothalamic blood flow via an indirect adrenergic-cholinergic interaction.
  Br J Pharmacol Volume: 71 Page(s): 623 - 629
  01/01/1980 Authors: Klugman KP; Lembeck F; Markowitz S; Mitchell G; Rosendorff C
• EFFECTS OF HEMORRHAGE ON COLLOIDS IN THE PIGEON
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 76 Page(s): 571 - 571
  01/01/1980 Authors: CORNELIUS ST; KLUGMAN KP; HATTINGH J
• EFFECT OF SUBSTANCE-P ON INTRA-CEREBRAL BLOOD-FLOW IN CONSCIOUS RABBITS
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 76 Page(s): 569 - 570
  01/01/1980 Authors: MARKOWITZ S; KLUGMAN KP; MITCHELL G; ROSENDORFF C; LEMBECK F
• CAROTID HEMODYNAMICS IN THE GIRAFFE
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 76 Page(s): 246 - 246
  01/01/1980 Authors: MITCHELL G; HEPBURN HR; MITCHELL D; SHIMELL C; BORSOOK D; FORD DM; KLUGMAN K; ROGERS G
• ACETYLCHOLINE-DEPENDENT RELEASE OF NORADRENALINE IN THE HYPOTHALAMUS
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 76 Page(s): 568 - 568
  01/01/1980 Authors: KLUGMAN KP; MITCHELL G; ROSENDORFF C; CANTRILL RC; BRENNAN MJW
• SEVERE HEMORRHAGE IN THE PIGEON DOES NOT ALTER THE OXYGEN-AFFINITY OF ITS BLOOD
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 76 Page(s): 135 - 136
  01/01/1980 Authors: WRIGHT PG; GANHAO MF; KLUGMAN KP; PALMER J
• CENTRAL NEUROGENIC MEDIATION OF THE CEREBROVASCULAR RESPONSE TO INHALED CO2
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 76 Page(s): 569 - 569
  01/01/1980 Authors: KLUGMAN KP; MITCHELL G; ROSENDORFF C
• 5-HYDROXYTRYPTAMINE MEDIATES THE EFFECT OF BACTERIAL-ENDOTOXIN ON BODY-TEMPERATURE IN RATS
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 76 Page(s): 326 - 326
  01/01/1980 Authors: KLUGMAN KP; FORD DM
• CHOLINERGIC REGULATION OF THE EFFECTS OF THE INTRA-CEREBRAL NORADRENERGIC PATHWAY
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 76 Page(s): 327 - 327
  01/01/1980 Authors: KLUGMAN KP; MITCHELL G; ROSENDORFF C
• Evidence for an indirect cholinergic regulation of blood flow in the hypothalamus of conscious rabbits.
  Br J Pharmacol Volume: 66 Page(s): 217 - 221
  06/01/1979 Authors: Klugman K; Mitchell G; Rosendorff C
• INDIRECT CHOLINERGIC CONTROL OF HYPOTHALAMIC BLOOD-FLOW
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 75 Page(s): 272 - 272
  01/01/1979 Authors: KLUGMAN KP; MITCHELL G; ROSENDORFF C
• DOES ACETYLCHOLINE APPROVE NORADRENALINES RELEASE
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 75 Page(s): 105 - 105
  01/01/1979 Authors: KLUGMAN K; MITCHELL G
• HEMATOLOGICAL RESPONSES TO HEMORRHAGE IN THE PIGEON
  SOUTH AFRICAN JOURNAL OF SCIENCE Volume: 75 Page(s): 276 - 277
  01/01/1979 Authors: PALMER J; KLUGMAN KP; HATTINGH J