Wenming Li

Department of Pharmacology & Chemical Biology
Instructor

wenming.li@emory.edu

Emory University School of Medicine
Department of Pharmacology, Whitehead Building, Room 565-1
615 Michael Street

Overview

Dr. Li is an Instructor in the lab of Dr. Xizu Mao, Professor of Pharmacology. Dr.Li's research interests focus on neurodegenerative disorders and relevant drug development.

Academic Appointment

Instructor, Pharmacology, Emory University School of Medicine

Research

Publications

Correction for Yan et al., "Molecular Determinants of Hepatitis B and D Virus Entry Restriction in Mouse Sodium Taurocholate Cotransporting Polypeptide".
J Virol Page(s): e0044525
04/16/2025 Authors: Yan H; Peng B; He W; Zhong G; Qi Y; Ren B; Gao Z; Jing Z; Song M; Xu G
New Insights on Hepatitis B Virus Viral Transcription in Single Hepatocytes.
Viruses Volume: 16
11/25/2024 Authors: Peng B; Pan L; Li W
Neuronal-enriched small extracellular vesicles trigger a PD-L1-mediated broad suppression of Tcells in Parkinson's disease.
iScience Volume: 27 Page(s): 110243
07/19/2024 Authors: Chen Z; Li W; Meng B; Xu C; Huang Y; Li G; Wen Z; Liu J; Mao Z
PreS1- targeting chimeric antigen receptor T cells diminish HBV infection in liver humanized FRG mice.
Virology Volume: 586 Page(s): 23 - 34
09/01/2023 Authors: Guo G; He W; Zhou Z; Diao Y; Sui J; Li W
An IgM-like inhalable ACE2 fusion protein broadly neutralizes SARS-CoV-2 variants.
Nat Commun Volume: 14 Page(s): 5191
08/25/2023 Authors: Liu J; Mao F; Chen J; Lu S; Qi Y; Sun Y; Fang L; Yeung ML; Liu C; Yu G
Molecular insights into Spindlin1-HBx interplay and its impact on HBV transcription from cccDNA minichromosome.
Nat Commun Volume: 14 Page(s): 4663
08/03/2023 Authors: Liu W; Yao Q; Su X; Deng Y; Yang M; Peng B; Zhao F; Du C; Zhang X; Zhu J
A spatiotemporally controlled recombinant cccDNA mouse model for studying HBV and developing drugs against the virus.
Antiviral Res Volume: 216 Page(s): 105642
08/01/2023 Authors: Zhou Z; Li C; Tan Z; Sun G; Peng B; Ren T; He J; Wang Y; Sun Y; Wang F
SLF2 Interacts with the SMC5/6 Complex to Direct Hepatitis B Virus Episomal DNA to Promyelocytic Leukemia Bodies for Transcriptional Repression.
J Virol Volume: 97 Page(s): e0032823
07/27/2023 Authors: Yao Q; Peng B; Li C; Li X; Chen M; Zhou Z; Tang D; He J; Wu Y; Sun Y
Nasal spray of an IgM-like ACE2 fusion protein HH-120 accelerates SARS-CoV-2 clearance: A single-center propensity score-matched cohort study.
J Med Virol Volume: 95 Page(s): e28805
05/01/2023 Authors: Song R; Chen X; Li B; Zhang H; Guo X; Liu Z; Zou L; Liang X; Lei C; Mao F
Nonproductive Hepatitis B Virus Covalently Closed Circular DNA Generates HBx-Related Transcripts from the HBx/Enhancer I Region and Acquires Reactivation by Superinfection in Single Cells.
J Virol Volume: 97 Page(s): e0171722
01/31/2023 Authors: Peng B; Jing Z; Zhou Z; Sun Y; Guo G; Tan Z; Diao Y; Yao Q; Ping Y; Li X
p38 MAPK-mediated loss of nuclear RNase III enzyme Drosha underlies amyloid beta-induced neuronal stress in Alzheimer's disease.
Aging Cell Volume: 20 Page(s): e13434
10/01/2021 Authors: Xu H; Liu X; Li W; Xi Y; Su P; Meng B; Shao X; Tang B; Yang Q; Mao Z
Entry of hepatitis B virus: going beyond NTCP to the nucleus.
Curr Opin Virol Volume: 50 Page(s): 97 - 102
10/01/2021 Authors: Tian J; Li C; Li W
Promising tacrine/huperzine A-based dimeric acetylcholinesterase inhibitors for neurodegenerative disorders: From relieving symptoms to modifying diseases through multitarget.
J Neurochem Volume: 158 Page(s): 1381 - 1393
09/01/2021 Authors: Mak S; Li W; Fu H; Luo J; Cui W; Hu S; Pang Y; Carlier PR; Tsim KW; Pi R
A simulated strategy for analysis of Short- to Long- chain fatty acids in mouse serum beyond chemical standards.
J Chromatogr B Analyt Technol Biomed Life Sci Volume: 1180 Page(s): 122895
08/15/2021 Authors: Wang X; Ruan H; Zong Z; Mao F; Wang Y; Jiao Y; Xu L; Yang T; Li W; Liu X
Transcriptionally inactive hepatitis B virus episome DNA preferentially resides in the vicinity of chromosome 19 in 3D host genome upon infection.
Cell Rep Volume: 35 Page(s): 109288
06/29/2021 Authors: Tang D; Zhao H; Wu Y; Peng B; Gao Z; Sun Y; Duan J; Qi Y; Li Y; Zhou Z
Design of Dimeric Bile Acid Derivatives as Potent and Selective Human NTCP Inhibitors.
J Med Chem Volume: 64 Page(s): 5973 - 6007
05/13/2021 Authors: Liu Y; Zhang L; Yan H; Wang Z; Sun G; Song X; Zhou Z; Peng B; Yan L; Wu Q
An Engineered Receptor-Binding Domain Improves the Immunogenicity of Multivalent SARS-CoV-2 Vaccines.
mBio Volume: 12
05/11/2021 Authors: Guo Y; He W; Mou H; Zhang L; Chang J; Peng S; Ojha A; Tavora R; Parcells MS; Luo G
Cryo-EM structure of S-Trimer, a subunit vaccine candidate for COVID-19.
J Virol Volume: 95
05/10/2021 Authors: Ma J; Su D; Sun Y; Huang X; Liang Y; Fang L; Ma Y; Li W; Liang P; Zheng S
Animal Models for Hepatitis B: Does the Supply Meet the Demand?
Gastroenterology Volume: 160 Page(s): 1437 - 1442
04/01/2021 Authors: Ploss A; Strick-Marchand H; Li W
Discovery and Identification of Arsenolipids Using a Precursor-Finder Strategy and Data-Independent Mass Spectrometry.
Environ Sci Technol Volume: 55 Page(s): 3836 - 3844
03/16/2021 Authors: Liu Q; Huang C; Li W; Fang Z; Le XC
[Novel vector preS1-tp fusion protein effectively inhibits hepatitis B virus replication and cccDNA synthesis by mediating hepatitis B virus targeting sequence small interfering RNA].
Zhonghua Gan Zang Bing Za Zhi Volume: 29 Page(s): 126 - 132
02/20/2021 Authors: Zeng YL; Gao F; Zhang C; Wei JF; Ma L; Ding GG; Li W; Shang J; Kang Y
Potent and Specific Inhibition of NTCP-Mediated HBV/HDV Infection and Substrate Transporting by a Novel, Oral-Available Cyclosporine A Analogue.
J Med Chem Volume: 64 Page(s): 543 - 565
01/14/2021 Authors: Liu Y; Ruan H; Li Y; Sun G; Liu X; He W; Mao F; He M; Yan L; Zhong G
NTCP Deficiency Causes Gallbladder Abnormalities in Mice and Human Beings.
Cell Mol Gastroenterol Hepatol Volume: 11 Page(s): 831 - 839
01/01/2021 Authors: Mao F; Wang M-X; Hou X; Zhou Z; Yan Y-Y; Fang L-J; Tan Z; Fang W-Y; Liu T; He W
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
Autophagy Volume: 17 Page(s): 1 - 382
01/01/2021 Authors: Klionsky DJ; Abdel-Aziz AK; Abdelfatah S; Abdellatif M; Abdoli A; Abel S; Abeliovich H; Abildgaard MH; Abudu YP; Acevedo-Arozena A
SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity.
Nat Commun Volume: 11 Page(s): 6013
11/26/2020 Authors: Zhang L; Jackson CB; Mou H; Ojha A; Peng H; Quinlan BD; Rangarajan ES; Pan A; Vanderheiden A; Suthar MS
Abnormal Bilirubin Metabolism in Patients With Sodium Taurocholate Cotransporting Polypeptide Deficiency.
J Pediatr Gastroenterol Nutr Volume: 71 Page(s): e138 - e141
11/01/2020 Authors: Yan YY; Wang MX; Gong JY; Liu LL; Setchell KDR; Xie XB; Wang NL; Li W; Wang J-S
Animal models for the study of human hepatitis B and D virus infection: New insights and progress.
Antiviral Res Volume: 182 Page(s): 104898
10/01/2020 Authors: Burwitz BJ; Zhou Z; Li W
[Clinical cure strategies for hepatitis B: direct-acting antiviral drugs].
Zhonghua Gan Zang Bing Za Zhi Volume: 28 Page(s): 640 - 644
08/20/2020 Authors: Huang AL; Yuan ZH; Nan YM; Yang DL; Guo JT; Li WH
Lack of antibody-mediated cross-protection between SARS-CoV-2 and SARS-CoV infections.
EBioMedicine Volume: 58 Page(s): 102890
08/01/2020 Authors: Yang R; Lan J; Huang B; A R; Lu M; Wang W; Wang W; Li W; Deng Y; Wong G
Dual-targeting nanoparticle vaccine elicits a therapeutic antibody response against chronic hepatitis B.
Nat Nanotechnol Volume: 15 Page(s): 406 - 416
05/01/2020 Authors: Wang W; Zhou X; Bian Y; Wang S; Chai Q; Guo Z; Wang Z; Zhu P; Peng H; Yan X
Novel Abs targeting the N-terminus of fibroblast growth factor19 inhibit hepatocellular carcinoma growth without bile-acid-related side-effects.
Cancer Sci Volume: 111 Page(s): 1750 - 1760
05/01/2020 Authors: Liu H; Zheng S; Hou X; Liu X; Du K; Lv X; Li Y; Yang F; Li W; Sui J
Targeting Hsc70-based autophagy to eliminate amyloid oligomers.
Biochem Biophys Res Commun Volume: 524 Page(s): 923 - 928
04/16/2020 Authors: Dou J; Su P; Xu C; Wen Z; Mao Z; Li W
Increased sulfation of bile acids in mice and human subjects with sodium taurocholate cotransporting polypeptide deficiency.
J Biol Chem Volume: 294 Page(s): 11853 - 11862
08/02/2019 Authors: Mao F; Liu T; Hou X; Zhao H; He W; Li C; Jing Z; Sui J; Wang F; Liu X
A quantitative method for hepatitis B virus covalently closed circular DNA enables distinguishing direct acting antivirals from cytotoxic agents.
Antiviral Res Volume: 168 Page(s): 197 - 202
08/01/2019 Authors: Gao Z; Yan L; Li W
A global scientific strategy to cure hepatitis B.
Lancet Gastroenterol Hepatol Volume: 4 Page(s): 545 - 558
07/01/2019 Authors: Revill PA; Chisari FV; Block JM; Dandri M; Gehring AJ; Guo H; Hu J; Kramvis A; Lampertico P; Janssen HLA
Severe fever with thrombocytopenia syndrome phlebovirus non-structural protein activates TPL2 signalling pathway for viral immunopathogenesis.
Nat Microbiol Volume: 4 Page(s): 429 - 437
03/01/2019 Authors: Choi Y; Park S-J; Sun Y; Yoo J-S; Pudupakam RS; Foo S-S; Shin W-J; Chen SB; Tsichlis PN; Lee W-J
Chaperone-mediated autophagy: Advances from bench to bedside.
Neurobiol Dis Volume: 122 Page(s): 41 - 48
02/01/2019 Authors: Li W; Nie T; Xu H; Yang J; Yang Q; Mao Z
Mechanisms Underlying Dysregulation of miR-132 in Alzheimer's Disease.
Biomed J Sci Tech Res Volume: 22 Page(s): 17018 - 17020
01/01/2019 Authors: Song Q; Dou J; Mao Z; Wen Z; Li W
The p.Ser267Phe variant of sodium taurocholate cotransporting polypeptide (NTCP) supports HBV infection with a low efficiency.
Virology Volume: 522 Page(s): 168 - 176
09/01/2018 Authors: Liu C; Xu G; Gao Z; Zhou Z; Guo G; Li D; Jing Z; Sui J; Li W
Receptor Usage of a Novel Bat Lineage C Betacoronavirus Reveals Evolution of Middle East Respiratory Syndrome-Related Coronavirus Spike Proteins for Human Dipeptidyl Peptidase 4 Binding.
J Infect Dis Volume: 218 Page(s): 197 - 207
06/20/2018 Authors: Lau SKP; Zhang L; Luk HKH; Xiong L; Peng X; Li KSM; He X; Zhao PS-H; Fan RYY; Wong ACP
The immune response of rhesus macaques to novel vaccines comprising hepatitis B virus S, PreS1, and Core antigens.
Vaccine Volume: 36 Page(s): 3740 - 3746
06/18/2018 Authors: Chuai X; Xie B; Chen H; Tan X; Wang W; Huang B; Deng Y; Li W; Tan W
Targeting Chaperone-Mediated Autophagy for Disease Therapy.
Curr Pharmacol Rep Volume: 4 Page(s): 261 - 275
06/01/2018 Authors: Li W; Dou J; Yang J; Xu H; She H
Silencing Retinoid X Receptor Alpha Expression Enhances Early-Stage Hepatitis B Virus Infection In Cell Cultures.
J Virol Volume: 92
04/15/2018 Authors: Song M; Sun Y; Tian J; He W; Xu G; Jing Z; Li W
Signaling and induction of chaperone-mediated autophagy by the endoplasmic reticulum under stress conditions.
Autophagy Volume: 14 Page(s): 1094 - 1096
01/01/2018 Authors: Li W; Yang Q; Mao Z
Phosphorylation of LAMP2A by p38 MAPK couples ER stress to chaperone-mediated autophagy.
Nat Commun Volume: 8 Page(s): 1763
11/24/2017 Authors: Li W; Zhu J; Dou J; She H; Tao K; Xu H; Yang Q; Mao Z
A potent human neutralizing antibody Fc-dependently reduces established HBV infections.
Elife Volume: 6
09/26/2017 Authors: Li D; He W; Liu X; Zheng S; Qi Y; Li H; Mao F; Liu J; Sun Y; Pan L
HBV core protein allosteric modulators differentially alter cccDNA biosynthesis from de novo infection and intracellular amplification pathways.
PLoS Pathog Volume: 13 Page(s): e1006658
09/01/2017 Authors: Guo F; Zhao Q; Sheraz M; Cheng J; Qi Y; Su Q; Cuconati A; Wei L; Du Y; Li W
Recombinant vaccinia vector-based vaccine (Tiantan) boosting a novel HBV subunit vaccine induced more robust and lasting immunity in rhesus macaques.
Vaccine Volume: 35 Page(s): 3347 - 3353
06/05/2017 Authors: Deng Y; Chuai X; Chen P; Chen H; Wang W; Ruan L; Li W; Tan W
Woodchuck sodium taurocholate cotransporting polypeptide supports low-level hepatitis B and D virus entry.
Virology Volume: 505 Page(s): 1 - 11
05/01/2017 Authors: Fu L; Hu H; Liu Y; Jing Z; Li W
MEF2D Mediates the Neuroprotective Effect of Methylene Blue Against Glutamate-Induced Oxidative Damage in HT22 Hippocampal Cells.
Mol Neurobiol Volume: 54 Page(s): 2209 - 2222
04/01/2017 Authors: Chen Z-W; Liu A; Liu Q; Chen J; Li W-M; Chao X-J; Yang Q; Liu P-Q; Mao Z-X; Pi R-B
Protective efficacy and hepatitis B virus clearance in mice enhanced by cell-mediated immunity with novel prime-boost regimens.
J Viral Hepat Volume: 24 Page(s): 337 - 345
04/01/2017 Authors: Chuai X; Chen P; Chen H; Wang W; Deng Y; Ruan L; Li W; Tan W
NTCP-Reconstituted In Vitro HBV Infection System.
Volume: 1540 Page(s): 1 - 14
01/01/2017 Authors: Sun Y; Qi Y; Peng B; Li W
DNA Polymerase Is a Key Cellular Factor for the Formation of Covalently Closed Circular DNA of Hepatitis B Virus.
PLoS Pathog Volume: 12 Page(s): e1005893
10/01/2016 Authors: Qi Y; Gao Z; Xu G; Peng B; Liu C; Yan H; Yao Q; Sun G; Liu Y; Tang D
Modification of Three Amino Acids in Sodium Taurocholate Cotransporting Polypeptide Renders Mice Susceptible to Infection with Hepatitis D Virus In Vivo.
J Virol Volume: 90 Page(s): 8866 - 8874
10/01/2016 Authors: He W; Cao Z; Mao F; Ren B; Li Y; Li D; Li H; Peng B; Yan H; Qi Y
A rapid and quantitative assay for measuring neutralizing antibodies of Coxsackievirus B3.
J Virol Methods Volume: 232 Page(s): 1 - 7
06/01/2016 Authors: Chen P; Wu X; Mao Q; Gao F; Hao X; Bian L; Zhu F; Li W; Xu M; Liang Z
Entry of hepatitis B and hepatitis D virus into hepatocytes: Basic insights and clinical implications.
J Hepatol Volume: 64 Page(s): S32 - S40
04/01/2016 Authors: Li W; Urban S
Erratum.
Autophagy Volume: 12 Page(s): 443
01/01/2016
Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Autophagy Volume: 12 Page(s): 1 - 222
01/01/2016 Authors: Klionsky DJ; Abdelmohsen K; Abe A; Abedin MJ; Abeliovich H; Acevedo Arozena A; Adachi H; Adams CM; Adams PD; Adeli K
NTCP opens the door for hepatitis B virus infection.
Antiviral Res Volume: 121 Page(s): 24 - 30
09/01/2015 Authors: Yan H; Liu Y; Sui J; Li W
Chaperone-mediated autophagy and neurodegeneration: connections, mechanisms, and therapeutic implications.
Neurosci Bull Volume: 31 Page(s): 407 - 415
08/01/2015 Authors: Liu X; Huang S; Wang X; Tang B; Li W; Mao Z
Human Coronavirus HKU1 Spike Protein Uses O-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme.
J Virol Volume: 89 Page(s): 7202 - 7213
07/01/2015 Authors: Huang X; Dong W; Milewska A; Golda A; Qi Y; Zhu QK; Marasco WA; Baric RS; Sims AC; Pyrc K
Hepatitis D Virus Infection of Mice Expressing Human Sodium Taurocholate Co-transporting Polypeptide.
PLoS Pathog Volume: 11 Page(s): e1004840
04/01/2015 Authors: He W; Ren B; Mao F; Jing Z; Li Y; Liu Y; Peng B; Yan H; Qi Y; Sun Y
Stress induces p38 MAPK-mediated phosphorylation and inhibition of Drosha-dependent cell survival.
Mol Cell Volume: 57 Page(s): 721 - 734
02/19/2015 Authors: Yang Q; Li W; She H; Dou J; Duong DM; Du Y; Yang S-H; Seyfried NT; Fu H; Gao G
The hepatitis B virus receptor.
Volume: 31 Page(s): 125 - 147
01/01/2015 Authors: Li W
Sodium taurocholate cotransporting polypeptide acts as a receptor for hepatitis B and D virus.
Dig Dis Volume: 33 Page(s): 388 - 396
01/01/2015 Authors: Yan H; Li W
Biological evaluation and SAR analysis of O-methylated analogs of quercetin as inhibitors of cancer cell proliferation.
Drug Dev Res Volume: 75 Page(s): 455 - 462
11/01/2014 Authors: Shi Z-H; Li N-G; Tang Y-P; Shi Q-P; Tang H; Li W; Zhang X; Fu H-A; Duan J-A
Oxidation of survival factor MEF2D in neuronal death and Parkinson's disease.
Antioxid Redox Signal Volume: 20 Page(s): 2936 - 2948
06/20/2014 Authors: Gao L; She H; Li W; Zeng J; Zhu J; Jones DP; Mao Z; Gao G; Yang Q
Viral entry of hepatitis B and D viruses and bile salts transportation share common molecular determinants on sodium taurocholate cotransporting polypeptide.
J Virol Volume: 88 Page(s): 3273 - 3284
03/01/2014 Authors: Yan H; Peng B; Liu Y; Xu G; He W; Ren B; Jing Z; Sui J; Li W
NTCP and beyond: opening the door to unveil hepatitis B virus entry.
Int J Mol Sci Volume: 15 Page(s): 2892 - 2905
02/19/2014 Authors: Watashi K; Urban S; Li W; Wakita T
microRNA expression in hepatitis B virus infected primary treeshrew hepatocytes and the independence of intracellular miR-122 level for de novo HBV infection in culture.
Virology Volume: 448 Page(s): 247 - 254
01/05/2014 Authors: Xu G; Gao Z; He W; Ma Y; Feng X; Cai T; Lu F; Liu L; Li W
Nonmuscle myosin heavy chain IIA is a critical factor contributing to the efficiency of early infection of severe fever with thrombocytopenia syndrome virus.
J Virol Volume: 88 Page(s): 237 - 248
01/01/2014 Authors: Sun Y; Qi Y; Liu C; Gao W; Chen P; Fu L; Peng B; Wang H; Jing Z; Zhong G
Site-specific engineering of chemical functionalities on the surface of live hepatitis D virus.
Angew Chem Int Ed Engl Volume: 52 Page(s): 13970 - 13974
12/23/2013 Authors: Lin S; Yan H; Li L; Yang M; Peng B; Chen S; Li W; Chen PR
Alpha-interferon suppresses hepadnavirus transcription by altering epigenetic modification of cccDNA minichromosomes.
PLoS Pathog Volume: 9 Page(s): e1003613
09/01/2013 Authors: Liu F; Campagna M; Qi Y; Zhao X; Guo F; Xu C; Li S; Li W; Block TM; Chang J
Molecular determinants of hepatitis B and D virus entry restriction in mouse sodium taurocholate cotransporting polypeptide.
J Virol Volume: 87 Page(s): 7977 - 7991
07/01/2013 Authors: Yan H; Peng B; He W; Zhong G; Qi Y; Ren B; Gao Z; Jing Z; Song M; Xu G
Sodium taurocholate cotransporting polypeptide mediates woolly monkey hepatitis B virus infection of Tupaia hepatocytes.
J Virol Volume: 87 Page(s): 7176 - 7184
06/01/2013 Authors: Zhong G; Yan H; Wang H; He W; Jing Z; Qi Y; Fu L; Gao Z; Huang Y; Xu G
Bis(12)-hupyridone, a novel acetylcholinesterase inhibitor, protects against glutamate-induced neuronal excitotoxicity via activating 7 nicotinic acetylcholine receptor/phosphoinositide 3-kinase/Akt cascade.
Volume: 203 Page(s): 365 - 370
03/25/2013 Authors: Cui W; Hu S; Chan HHN; Luo J; Li W; Mak S; Choi TC; Rong J; Carlier PR; Han Y
The anti-cancer agent SU4312 unexpectedly protects against MPP(+) -induced neurotoxicity via selective and direct inhibition of neuronal NOS.
Br J Pharmacol Volume: 168 Page(s): 1201 - 1214
03/01/2013 Authors: Cui W; Zhang Z; Li W; Hu S; Mak S; Zhang H; Han R; Yuan S; Li S; Sa F
TIM-family proteins promote infection of multiple enveloped viruses through virion-associated phosphatidylserine.
PLoS Pathog Volume: 9 Page(s): e1003232
03/01/2013 Authors: Jemielity S; Wang JJ; Chan YK; Ahmed AA; Li W; Monahan S; Bu X; Farzan M; Freeman GJ; Umetsu DT
Development and evaluation of a pseudovirus-luciferase assay for rapid and quantitative detection of neutralizing antibodies against enterovirus 71.
PLoS One Volume: 8 Page(s): e64116
01/01/2013 Authors: Wu X; Mao Q; Yao X; Chen P; Chen X; Shao J; Gao F; Yu X; Zhu F; Li R
Sodium taurocholate cotransporting polypeptide is a functional receptor for human hepatitis B and D virus.
Elife Volume: 1 Page(s): e00049
11/13/2012 Authors: Yan H; Zhong G; Xu G; He W; Jing Z; Gao Z; Huang Y; Qi Y; Peng B; Wang H
Activation of transcription factor MEF2D by bis(3)-cognitin protects dopaminergic neurons and ameliorates Parkinsonian motor defects.
J Biol Chem Volume: 287 Page(s): 34246 - 34255
10/05/2012 Authors: Yao L; Li W; She H; Dou J; Jia L; He Y; Yang Q; Zhu J; Cpiro NL; Walker DI
The effects of chronic copper exposure on the amyloid protein metabolisim associated genes' expression in chronic cerebral hypoperfused rats.
Neurosci Lett Volume: 518 Page(s): 14 - 18
06/14/2012 Authors: Mao X; Ye J; Zhou S; Pi R; Dou J; Zang L; Chen X; Chao X; Li W; Liu M
Guidelines for the use and interpretation of assays for monitoring autophagy.
Autophagy Volume: 8 Page(s): 445 - 544
04/01/2012 Authors: Klionsky DJ; Abdalla FC; Abeliovich H; Abraham RT; Acevedo-Arozena A; Adeli K; Agholme L; Agnello M; Agostinis P; Aguirre-Ghiso JA
Molecular determinants of enterovirus 71 viral entry: cleft around GLN-172 on VP1 protein interacts with variable region on scavenge receptor B 2.
J Biol Chem Volume: 287 Page(s): 6406 - 6420
02/24/2012 Authors: Chen P; Song Z; Qi Y; Feng X; Xu N; Sun Y; Wu X; Yao X; Mao Q; Li X
Calpain-mediated degradation of myocyte enhancer factor 2D contributes to excitotoxicity by activation of extrasynaptic N-methyl-D-aspartate receptors.
J Biol Chem Volume: 287 Page(s): 5797 - 5805
02/17/2012 Authors: Wei G; Yin Y; Li W; Bito H; She H; Mao Z
Unexpected neuronal protection of SU5416 against 1-Methyl-4-phenylpyridinium ion-induced toxicity via inhibiting neuronal nitric oxide synthase.
PLoS One Volume: 7 Page(s): e46253
01/01/2012 Authors: Cui W; Zhang Z; Li W; Mak S; Hu S; Zhang H; Yuan S; Rong J; Choi TC; Lee SMY
Modulation of Neuronal Survival Factor MEF2 by Kinases in Parkinson's Disease.
Front Physiol Volume: 3 Page(s): 171
01/01/2012 Authors: Yin Y; She H; Li W; Yang Q; Guo S; Mao Z
Tacrine-6-ferulic acid, a novel multifunctional dimer, inhibits amyloid--mediated Alzheimer's disease-associated pathogenesis in vitro and in vivo.
PLoS One Volume: 7 Page(s): e31921
01/01/2012 Authors: Pi R; Mao X; Chao X; Cheng Z; Liu M; Duan X; Ye M; Chen X; Mei Z; Liu P
Neuroprotection against excitotoxic and ischemic insults by bis(12)-hupyridone, a novel anti-acetylcholinesterase dimer, possibly via acting on multiple targets.
Brain Res Volume: 1421 Page(s): 100 - 109
11/03/2011 Authors: Zhao Y; Dou J; Luo J; Li W; Chan HHN; Cui W; Zhang H; Han R; Carlier PR; Zhang X
PI3-K/Akt and ERK pathways activated by VEGF play opposite roles in MPP+-induced neuronal apoptosis.
Neurochem Int Volume: 59 Page(s): 945 - 953
11/01/2011 Authors: Cui W; Li W; Han R; Mak S; Zhang H; Hu S; Rong J; Han Y
Cdk5: mediator of neuronal development, death and the response to DNA damage.
Mech Ageing Dev Volume: 132 Page(s): 389 - 394
08/01/2011 Authors: Zhu J; Li W; Mao Z
Chaperone-mediated autophagy: machinery, regulation and biological consequences.
Cell Mol Life Sci Volume: 68 Page(s): 749 - 763
03/01/2011 Authors: Li W; Yang Q; Mao Z
Sulfated tyrosines 27 and 29 in the N-terminus of human CXCR3 participate in binding native IP-10.
Acta Pharmacol Sin Volume: 30 Page(s): 193 - 201
02/01/2009 Authors: Gao J-M; Xiang R-L; Jiang L; Li W-H; Feng Q-P; Guo Z-J; Sun Q; Zeng Z-P; Fang F-D
Structural basis for activation and inhibition of the secreted chlamydia protease CPAF.
Cell Host Microbe Volume: 4 Page(s): 529 - 542
12/11/2008 Authors: Huang Z; Feng Y; Chen D; Wu X; Huang S; Wang X; Xiao X; Li W; Huang N; Gu L
Influenza A virus neuraminidase limits viral superinfection.
J Virol Volume: 82 Page(s): 4834 - 4843
05/01/2008 Authors: Huang I-C; Li W; Sui J; Marasco W; Choe H; Farzan M
The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2.
Virology Volume: 367 Page(s): 367 - 374
10/25/2007 Authors: Li W; Sui J; Huang I-C; Kuhn JH; Radoshitzky SR; Marasco WA; Choe H; Farzan M
Transferrin receptor 1 is a cellular receptor for New World haemorrhagic fever arenaviruses.
Nature Volume: 446 Page(s): 92 - 96
03/01/2007 Authors: Radoshitzky SR; Abraham J; Spiropoulou CF; Kuhn JH; Nguyen D; Li W; Nagel J; Schmidt PJ; Nunberg JH; Andrews NC
Severe acute respiratory syndrome coronavirus entry as a target of antiviral therapies.
Antivir Ther Volume: 12 Page(s): 639 - 650
01/01/2007 Authors: Kuhn JH; Li W; Radoshitzky SR; Choe H; Farzan M
Conformational states of the severe acute respiratory syndrome coronavirus spike protein ectodomain.
J Virol Volume: 80 Page(s): 6794 - 6800
07/01/2006 Authors: Li F; Berardi M; Li W; Farzan M; Dormitzer PR; Harrison SC
Conserved receptor-binding domains of Lake Victoria marburgvirus and Zaire ebolavirus bind a common receptor.
J Biol Chem Volume: 281 Page(s): 15951 - 15958
06/09/2006 Authors: Kuhn JH; Radoshitzky SR; Guth AC; Warfield KL; Li W; Vincent MJ; Towner JS; Nichol ST; Bavari S; Choe H
Cross-neutralization of human and palm civet severe acute respiratory syndrome coronaviruses by antibodies targeting the receptor-binding domain of spike protein.
J Immunol Volume: 176 Page(s): 6085 - 6092
05/15/2006 Authors: He Y; Li J; Li W; Lustigman S; Farzan M; Jiang S
Animal origins of the severe acute respiratory syndrome coronavirus: insight from ACE2-S-protein interactions.
J Virol Volume: 80 Page(s): 4211 - 4219
05/01/2006 Authors: Li W; Wong S-K; Li F; Kuhn JH; Huang I-C; Choe H; Farzan M
SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells.
J Biol Chem Volume: 281 Page(s): 3198 - 3203
02/10/2006 Authors: Huang I-C; Bosch BJ; Li F; Li W; Lee KH; Ghiran S; Vasilieva N; Dermody TS; Harrison SC; Dormitzer PR
SARS-CoV, but not HCoV-NL63, utilizes cathepsins to infect cells: viral entry.
Volume: 581 Page(s): 335 - 338
01/01/2006 Authors: Huang I-C; Bosch BJ; Li W; Farzan M; Rottier PM; Choe H
Insights from the association of SARS-CoV S-protein with its receptor, ACE2.
Volume: 581 Page(s): 209 - 218
01/01/2006 Authors: Li W; Choe H; Farzan M
Interactions between SARS coronavirus and its receptor.
Volume: 581 Page(s): 229 - 234
01/01/2006 Authors: Li F; Li W; Farzan M; Harrison SC
Antibody responses against SARS coronavirus are correlated with disease outcome of infected individuals.
J Med Virol Volume: 78 Page(s): 1 - 8
01/01/2006 Authors: Zhang L; Zhang F; Yu W; He T; Yu J; Yi CE; Ba L; Li W; Farzan M; Chen Z
Structure of SARS coronavirus spike receptor-binding domain complexed with receptor.
Science Volume: 309 Page(s): 1864 - 1868
09/16/2005 Authors: Li F; Li W; Farzan M; Harrison SC
Evaluation of human monoclonal antibody 80R for immunoprophylaxis of severe acute respiratory syndrome by an animal study, epitope mapping, and analysis of spike variants.
J Virol Volume: 79 Page(s): 5900 - 5906
05/01/2005 Authors: Sui J; Li W; Roberts A; Matthews LJ; Murakami A; Vogel L; Wong SK; Subbarao K; Farzan M; Marasco WA
Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2.
EMBO J Volume: 24 Page(s): 1634 - 1643
04/20/2005 Authors: Li W; Zhang C; Sui J; Kuhn JH; Moore MJ; Luo S; Wong S-K; Huang I-C; Xu K; Vasilieva N
Sulphated tyrosines mediate association of chemokines and Plasmodium vivax Duffy binding protein with the Duffy antigen/receptor for chemokines (DARC).
Mol Microbiol Volume: 55 Page(s): 1413 - 1422
03/01/2005 Authors: Choe H; Moore MJ; Owens CM; Wright PL; Vasilieva N; Li W; Singh AP; Shakri R; Chitnis CE; Farzan M
Activity deprivation-dependent induction of the proapoptotic BH3-only protein Bim is independent of JNK/c-Jun activation during apoptosis in cerebellar granule neurons.
Neurosci Lett Volume: 375 Page(s): 7 - 12
02/25/2005 Authors: Shi L; Gong S; Yuan Z; Ma C; Liu Y; Wang C; Li W; Pi R; Huang S; Chen R
Receptor-binding domain of SARS-CoV spike protein induces highly potent neutralizing antibodies: implication for developing subunit vaccine.
Biochem Biophys Res Commun Volume: 324 Page(s): 773 - 781
11/12/2004 Authors: He Y; Zhou Y; Liu S; Kou Z; Li W; Farzan M; Jiang S
Angiotensin-converting enzyme 2: a functional receptor for SARS coronavirus.
Cell Mol Life Sci Volume: 61 Page(s): 2738 - 2743
11/01/2004 Authors: Kuhn JH; Li W; Choe H; Farzan M
Efficient replication of severe acute respiratory syndrome coronavirus in mouse cells is limited by murine angiotensin-converting enzyme 2.
J Virol Volume: 78 Page(s): 11429 - 11433
10/01/2004 Authors: Li W; Greenough TC; Moore MJ; Vasilieva N; Somasundaran M; Sullivan JL; Farzan M; Choe H
Retroviruses pseudotyped with the severe acute respiratory syndrome coronavirus spike protein efficiently infect cells expressing angiotensin-converting enzyme 2.
J Virol Volume: 78 Page(s): 10628 - 10635
10/01/2004 Authors: Moore MJ; Dorfman T; Li W; Wong SK; Li Y; Kuhn JH; Coderre J; Vasilieva N; Han Z; Greenough TC
[Potent neutralization antibody elicited in mice by SARS-associated coronavirus spike protein S1 domain].
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi Volume: 18 Page(s): 258 - 260
09/01/2004 Authors: Zhang Y; Yang F; Li Y-H; Li W-H; Tu X-M; Wei Q; Zhu H; Liu L; Wang H; Qin C
Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association.
Proc Natl Acad Sci U S A Volume: 101 Page(s): 2536 - 2541
02/24/2004 Authors: Sui J; Li W; Murakami A; Tamin A; Matthews LJ; Wong SK; Moore MJ; Tallarico ASC; Olurinde M; Choe H
SP600125, a new JNK inhibitor, protects dopaminergic neurons in the MPTP model of Parkinson's disease.
Neurosci Res Volume: 48 Page(s): 195 - 202
02/01/2004 Authors: Wang W; Shi L; Xie Y; Ma C; Li W; Su X; Huang S; Chen R; Zhu Z; Mao Z
A 193-amino acid fragment of the SARS coronavirus S protein efficiently binds angiotensin-converting enzyme 2.
J Biol Chem Volume: 279 Page(s): 3197 - 3201
01/30/2004 Authors: Wong SK; Li W; Moore MJ; Choe H; Farzan M
[Recombinant replication-defective adenovirus based rabies vaccine].
Zhongguo Yi Xue Ke Xue Yuan Xue Bao Volume: 25 Page(s): 650 - 654
12/01/2003 Authors: Li W-H; Zhang Y; Wang S-H; Liu L; Yang F
Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus.
Nature Volume: 426 Page(s): 450 - 454
11/27/2003 Authors: Li W; Moore MJ; Vasilieva N; Sui J; Wong SK; Berne MA; Somasundaran M; Sullivan JL; Luzuriaga K; Greenough TC
Tyrosine sulfation of human antibodies contributes to recognition of the CCR5 binding region of HIV-1 gp120.
Cell Volume: 114 Page(s): 161 - 170
07/25/2003 Authors: Choe H; Li W; Wright PL; Vasilieva N; Venturi M; Huang C-C; Grundner C; Dorfman T; Zwick MB; Wang L
Tyrosine-sulfated peptides functionally reconstitute a CCR5 variant lacking a critical amino-terminal region.
J Biol Chem Volume: 277 Page(s): 40397 - 40402
10/25/2002 Authors: Farzan M; Chung S; Li W; Vasilieva N; Wright PL; Schnitzler CE; Marchione RJ; Gerard C; Gerard NP; Sodroski J
[Immune response of mice to replication-defective recombinant adenovirus containing glycoprotein gene of rabies virus 3aG strain].
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi Volume: 15 Page(s): 61 - 65
03/01/2001 Authors: Li W; Zhang Y; Wang S
Expression of glycoprotein gene of the rabies virus 3aG strain by E-3 deleted adenovirus recombinant.
Zhonghua Shi Yan He Lin Chuang Bing Du Xue Za Zhi Volume: 14 Page(s): 281 - 284
09/01/2000 Authors: Zhang X; Zhang Y; Li W

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Wenming Li

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