Publications

• The immune interactions of gut glycans and microbiota in health and disease.
  Mol Microbiol Volume: 122 Page(s): 313 - 330
  09/01/2024 Authors: Demirturk M; Cinar MS; Avci FY
• Erratum for Cinar et al., "Serine-rich repeat proteins: well-known yet little-understood bacterial adhesins".
  J Bacteriol Volume: 206 Page(s): e0015324
  06/20/2024 Authors: Cinar MS; Niyas A; Avci FY
• Serine-rich repeat proteins: well-known yet little-understood bacterial adhesins.
  J Bacteriol Volume: 206 Page(s): e0024123
  01/25/2024 Authors: Cinar MS; Niyas A; Avci FY
• Tn antigen interactions of macrophage galactose-type lectin (MGL) in immune function and disease.
  Glycobiology Volume: 33 Page(s): 879 - 887
  12/25/2023 Authors: Tumoglu B; Keelaghan A; Avci FY
• Emerging vaccine strategies against the incessant pneumococcal disease.
  NPJ Vaccines Volume: 8 Page(s): 122
  08/17/2023 Authors: Duke JA; Avci FY
• Prevalence and Homology of the Pneumococcal Serine-Rich Repeat Protein at the Global Scale.
  Microbiol Spectr Volume: 11 Page(s): e0325222
  06/15/2023 Authors: Aceil J; Venkat A; Pan E; Kannan N; Avci FY
• Targeted therapeutic agent for Streptococcus pneumoniae stereotype 3 infection
  Volume: 32 Page(s): 999 - 999
  10/31/2022 Authors: Niyas AMM; Paschall AY; Avci FY
• Carbohydrate Antigens Induce Immune Evasion Mechanisms in a Murine Breast Cancer Model
  Volume: 32 Page(s): 987 - 987
  10/31/2022 Authors: Paschall AV; Ozdilek A; Stoigny S; Sun L; Avci F
• Carbohydrate specific T cell stimulation by HIV envelope glycoprotein
  Volume: 32 Page(s): 1013 - 1013
  10/31/2022 Authors: Nawaz FZ; Paschall AV; Sun L; Avci FY
• Immunogenicity and protective efficacy of a prototype pneumococcal bioconjugate vaccine.
  Vaccine Volume: 40 Page(s): 6107 - 6113
  10/06/2022 Authors: Aceil J; Paschall AV; Knoot CJ; Robinson LS; Scott NE; Feldman MF; Harding CM; Avci FY
• Glycosylation as a key parameter in the design of nucleic acid vaccines.
  Curr Opin Struct Biol Volume: 73 Page(s): 102348
  04/01/2022 Authors: Ozdilek A; Avci FY
• Modulation of immunosuppressant drug treatment to improve SARS-CoV-2 vaccine efficacy in mice.
  Vaccine Volume: 40 Page(s): 854 - 861
  02/07/2022 Authors: Paschall AV; Ozdilek A; Briner SL; Brindley MA; Avci FY
• Harnessing galactose oxidase in the development of a chemoenzymatic platform for glycoconjugate vaccine design.
  J Biol Chem Volume: 298 Page(s): 101453
  01/01/2022 Authors: Duke JA; Paschall AV; Glushka J; Lees A; Moremen KW; Avci FY
• Pneumococcal Surface Proteins as Virulence Factors, Immunogens, and Conserved Vaccine Targets.
  Front Cell Infect Microbiol Volume: 12 Page(s): 832254
  01/01/2022 Authors: Aceil J; Avci FY
• Immune interactions of viral surface glycoproteins
  Volume: 31 Page(s): 1696 - 1696
  12/01/2021 Authors: Avci F
• Immuno-modulatory Siglec-9 ligands expressed by epithelial cells of the human choroid plexus
  Volume: 31 Page(s): 1694 - 1694
  12/01/2021 Authors: Rosenbalm K; Nix DB; Bakshi B; Paschall AV; Avci FY; Tiemeyer M
• Development and Immunogenicity of a Prototype Multivalent Group B Streptococcus Bioconjugate Vaccine.
  ACS Infect Dis Volume: 7 Page(s): 3111 - 3123
  11/12/2021 Authors: Duke JA; Paschall AV; Robinson LS; Knoot CJ; Vinogradov E; Scott NE; Feldman MF; Avci FY; Harding CM
• A Structural Model for the Ligand Binding of Pneumococcal Serotype 3 Capsular Polysaccharide-Specific Protective Antibodies.
  mBio Volume: 12 Page(s): e0080021
  06/29/2021 Authors: Ozdilek A; Huang J; Babb R; Paschall AV; Middleton DR; Duke JA; Pirofski L-A; Mousa JJ; Avci FY
• Broadly reactive human antibodies prevent and treat pneumococcal infection
  Volume: 206
  05/01/2021 Authors: Mousa JJ; Huang J; Gingerich AD; Royer F; Paschall AV; Avci FY
• Broadly Reactive Human Monoclonal Antibodies Targeting the Pneumococcal Histidine Triad Protein Protect against Fatal Pneumococcal Infection.
  Infect Immun Volume: 89
  04/16/2021 Authors: Huang J; Gingerich AD; Royer F; Paschall AV; Pena-Briseno A; Avci FY; Mousa JJ
• Characterization of the -glucuronidase Pn3Pase as the founding member of glycoside hydrolase family GH169.
  Glycobiology Volume: 31 Page(s): 266 - 274
  04/01/2021 Authors: Wantuch PL; Jella S; Duke JA; Mousa JJ; Henrissat B; Glushka J; Avci FY
• Glycosyltransferases within the psrP Locus Facilitate Pneumococcal Virulence.
  J Bacteriol Volume: 203
  03/08/2021 Authors: Middleton DR; Aceil J; Mustafa S; Paschall AV; Avci FY
• FAP-Targeted Photodynamic Therapy Mediated by Ferritin Nanoparticles Elicits an Immune Response against Cancer Cells and Cancer Associated Fibroblasts.
  Adv Funct Mater Volume: 31
  02/10/2021 Authors: Zhou S; Zhen Z; Paschall AV; Xue L; Yang X; Bebin-Blackwell A-G; Cao Z; Zhang W; Wang M; Teng Y
• Glycosyltransferases within the psrP locus facilitate pneumococcal virulence
  Volume: 30 Page(s): 1029 - 1029
  12/01/2020 Authors: Middleton D; Aceil J; Mustafa S; Avci F
• Glycan-Mediated Immune Evasion in Breast Cancer
  Volume: 30 Page(s): 1091 - 1091
  12/01/2020 Authors: Paschall AV; Ozdilek A; Stogniy O; Avci FY
• Therapeutic Activity of Type 3 Streptococcus pneumoniae Capsule Degrading Enzyme Pn3Pase.
  Pharm Res Volume: 37 Page(s): 236
  11/02/2020 Authors: Paschall AV; Middleton DR; Wantuch PL; Avci FY
• 2020 FASEB Science Research Conference on Microbial Glycobiology, July 13-14, 2020.
  FASEB J Volume: 34 Page(s): 14069 - 14072
  11/01/2020 Authors: Juge N; Avci F; Scott NE; Creuzenet C; Valvano MA
• Glycopeptide epitope facilitates HIV-1 envelope specific humoral immune responses by eliciting T cell help.
  Nat Commun Volume: 11 Page(s): 2550
  05/21/2020 Authors: Sun L; Paschall AV; Middleton DR; Ishihara M; Ozdilek A; Wantuch PL; Aceil J; Duke JA; LaBranche CC; Tiemeyer M
• Isolation and characterization of new human carrier peptides from two important vaccine immunogens.
  Vaccine Volume: 38 Page(s): 2315 - 2325
  02/28/2020 Authors: Wantuch PL; Sun L; LoPilato RK; Mousa JJ; Haltiwanger RS; Avci FY
• Host protein glycosylation in nucleic acid vaccines as a potential hurdle in vaccine design for nonviral pathogens.
  Proc Natl Acad Sci U S A Volume: 117 Page(s): 1280 - 1282
  01/21/2020 Authors: Ozdilek A; Paschall AV; Dookwah M; Tiemeyer M; Avci FY
• NaCl Nanoparticles as a Cancer Therapeutic.
  Adv Mater Volume: 31 Page(s): e1904058
  11/01/2019 Authors: Jiang W; Yin L; Chen H; Paschall AV; Zhang L; Fu W; Zhang W; Todd T; Yu KS; Zhou S
• Glycoconjugates: What It Would Take To Master These Well-Known yet Little-Understood Immunogens for Vaccine Development.
  mSphere Volume: 4
  09/25/2019 Authors: Avci F; Berti F; Dull P; Hennessey J; Pavliak V; Prasad AK; Vann W; Wacker M; Marcq O
• Opsonophagocytic Killing Assay to Assess Immunological Responses Against Bacterial Pathogens.
  J Vis Exp
  04/05/2019 Authors: Paschall AV; Middleton DR; Avci FY
• Synthesis of neoglycoproteins as potential biomarkers and vaccines for Chagas disease
  Volume: 257
  03/31/2019 Authors: Carvajal EG; Portillo S; Avci F; Almeida IC; Michael K
• Glycoconjugate synthesis using chemoselective ligation.
  Org Biomol Chem Volume: 17 Page(s): 2646 - 2650
  03/06/2019 Authors: Cheng S; Wantuch PL; Kizer ME; Middleton DR; Wang R; DiBello M; Li M; Wang X; Li X; Ramachandiran V
• Invasive pneumococcal disease in relation to vaccine type serotypes.
  Hum Vaccin Immunother Volume: 15 Page(s): 874 - 875
  01/01/2019 Authors: Wantuch PL; Avci FY
• Immunological characterization of protein glycosylation in Streptococcus pneumoniae
  Volume: 28 Page(s): 1014 - 1014
  12/01/2018 Authors: Middleton DR; Aceil J; Sun L; Duke JA; Avci FY
• Modulating Tn-Mediated Immune Suppression in Breast Cancer
  Volume: 28 Page(s): 1052 - 1053
  12/01/2018 Authors: Paschall A; Ozdilek A; Aceil J; Avci F
• Metabolic labeling of HIV-1 envelope glycoprotein gp120 to elucidate the effect of gp120 glycosylation on antigen uptake.
  J Biol Chem Volume: 293 Page(s): 15178 - 15194
  09/28/2018 Authors: Sun L; Ishihara M; Middleton DR; Tiemeyer M; Avci FY
• Enzymatic Hydrolysis of Pneumococcal Capsular Polysaccharide Renders the Bacterium Vulnerable to Host Defense.
  Infect Immun Volume: 86
  08/01/2018 Authors: Middleton DR; Paschall AV; Duke JA; Avci FY
• Identification and characterization of the Streptococcus pneumoniae type 3 capsule-specific glycoside hydrolase of Paenibacillus species 32352.
  Glycobiology Volume: 28 Page(s): 90 - 99
  02/01/2018 Authors: Middleton DR; Zhang X; Wantuch PL; Ozdilek A; Liu X; LoPilato R; Gangasani N; Bridger R; Wells L; Linhardt RJ
• Current status and future directions of invasive pneumococcal diseases and prophylactic approaches to control them.
  Hum Vaccin Immunother Volume: 14 Page(s): 2303 - 2309
  01/01/2018 Authors: Wantuch PL; Avci FY
• Therapeutic and prophylactic approaches for pneumococcal infection
  Volume: 254
  08/20/2017 Authors: Avci F
• T Cell-Mediated Humoral Immune Responses to Type 3 Capsular Polysaccharide of Streptococcus pneumoniae.
  J Immunol Volume: 199 Page(s): 598 - 603
  07/15/2017 Authors: Middleton DR; Sun L; Paschall AV; Avci FY
• Complete Genome Sequence of the Bacterium Bacillus circulans Jordan Strain 32352.
  Genome Announc Volume: 5
  05/11/2017 Authors: Middleton DR; Lorenz W; Avci FY
• Rapid screening of sugar-nucleotide donor specificities of putative glycosyltransferases.
  Glycobiology Volume: 27 Page(s): 206 - 212
  03/01/2017 Authors: Sheikh MO; Halmo SM; Patel S; Middleton D; Takeuchi H; Schafer CM; West CM; Haltiwanger RS; Avci FY; Moremen KW
• Molecular Mechanisms for Carbohydrate Presentation to CD4+T cells by MHCII Pathway
  Volume: 26 Page(s): 1483 - 1483
  12/01/2016 Authors: Wantuch PL; Middleton DR; Sun L; Avci FY
• Carbohydrate specific T cell stimulation by HIV envelope glycoprotein
  Volume: 26 Page(s): 1448 - 1449
  12/01/2016 Authors: Ozdilek A; Sun L; Middleton DR; Avci FY
• Enzymatic hydrolysis of pneumococcal type III polysaccharide
  Volume: 26 Page(s): 1440 - 1440
  12/01/2016 Authors: Middleton DR; Wantuch PL; Avci FY
• Carbohydrate-specific adaptive immune responses
  Volume: 26 Page(s): 1386 - 1386
  12/01/2016 Authors: Avci FY
• A chicken vaccine to protect humans from diarrheal disease.
  Glycobiology Volume: 26 Page(s): 1137 - 1139
  11/01/2016 Authors: Avci FY
• Carbohydrates as T-cell antigens with implications in health and disease.
  Glycobiology Volume: 26 Page(s): 1029 - 1040
  10/01/2016 Authors: Sun L; Middleton DR; Wantuch PL; Ozdilek A; Avci FY
• Carbohydrate specific T cell stimulation by HIV envelope glycoprotein
  Volume: 196
  05/01/2016 Authors: Sun L; Ozdilek A; Middleton DR; Avci FY
• Adaptive humoral immune responses to type Ill capsular polysaccharide of Streptococcus pneumoniae
  Volume: 196
  05/01/2016 Authors: Middleton DR; Wantuch P; Sun L; Avci FY
• Profiling pneumococcal type 3-derived oligosaccharides by high resolution liquid chromatography-tandem mass spectrometry.
  J Chromatogr A Volume: 1397 Page(s): 43 - 51
  06/05/2015 Authors: Li G; Li L; Xue C; Middleton D; Linhardt RJ; Avci FY
• The microbiome regulates the homeostasis of host invariant natural killer T (iNKT) cells
  Volume: 192
  05/01/2014 Authors: An D; Oh S; Olszak T; Neves J; Avci F; Erturk-Hasdemir D; Zeissig S; Blumberg R; Kasper D
• Sphingolipids from a symbiotic microbe regulate homeostasis of host intestinal natural killer T cells.
  Cell Volume: 156 Page(s): 123 - 133
  01/16/2014 Authors: An D; Oh SF; Olszak T; Neves JF; Avci FY; Erturk-Hasdemir D; Lu X; Zeissig S; Blumberg RS; Kasper DL
• A maternal vaccine against group B Streptococcus: past, present, and future.
  Vaccine Volume: 31 Suppl 4 Page(s): D13 - D19
  08/28/2013 Authors: Chen VL; Avci FY; Kasper DL
• Carbohydrates and T cells: a sweet twosome.
  Semin Immunol Volume: 25 Page(s): 146 - 151
  04/01/2013 Authors: Avci FY; Li X; Tsuji M; Kasper DL
• Novel strategies for development of next-generation glycoconjugate vaccines.
  Curr Top Med Chem Volume: 13 Page(s): 2535 - 2540
  01/01/2013 Authors: Avci FY
• Isolation of carbohydrate-specific CD4(+) T cell clones from mice after stimulation by two model glycoconjugate vaccines.
  Nat Protoc Volume: 7 Page(s): 2180 - 2192
  12/01/2012 Authors: Avci FY; Li X; Tsuji M; Kasper DL
• A new model for T cell-dependent immune activation by glycoconjugate vaccines
  Volume: 22 Page(s): 1538 - 1538
  11/01/2012 Authors: Avci FY; Li X; Tsuji M; Kasper D
• A mechanism for glycoconjugate vaccine activation of the adaptive immune system and its implications for vaccine design.
  Nat Med Volume: 17 Page(s): 1602 - 1609
  11/20/2011 Authors: Avci FY; Li X; Tsuji M; Kasper DL
• Alternative mechanism for glycoconjugate vaccine activation of the adaptive immune system
  Volume: 186
  04/01/2011 Authors: Avci F; Li X; Tsuji M; Kasper D
• How bacterial carbohydrates influence the adaptive immune system.
  Annu Rev Immunol Volume: 28 Page(s): 107 - 130
  01/01/2010 Authors: Avci FY; Kasper DL
• The pgaABCD locus of Acinetobacter baumannii encodes the production of poly-beta-1-6-N-acetylglucosamine, which is critical for biofilm formation.
  J Bacteriol Volume: 191 Page(s): 5953 - 5963
  10/01/2009 Authors: Choi AHK; Slamti L; Avci FY; Pier GB; Maira-Litrn T
• Microbial carbohydrate depolymerization by antigen-presenting cells: deamination prior to presentation by the MHCII pathway.
  Proc Natl Acad Sci U S A Volume: 105 Page(s): 5183 - 5188
  04/01/2008 Authors: Duan J; Avci FY; Kasper DL
• Acceptor specificity of the Pasteurella hyaluronan and chondroitin synthases and production of chimeric glycosaminoglycans.
  J Biol Chem Volume: 282 Page(s): 337 - 344
  01/05/2007 Authors: Tracy BS; Avci FY; Linhardt RJ; DeAngelis PL
• Enzymatic redesigning of biologically active heparan sulfate
  Volume: 25 Page(s): S42 - S42
  11/01/2006 Authors: Liu J; Chen J; Avci FY; Munoz EM; McDowell LM; Chen M; Pedersen LC; Zhang L; Linhardt RJ
• Matrix-assisted laser desorption/ionization mass spectrometric analysis of uncomplexed highly sulfated oligosaccharides using ionic liquid matrices.
  Anal Chem Volume: 78 Page(s): 1774 - 1779
  03/15/2006 Authors: Laremore TN; Murugesan S; Park T-J; Avci FY; Zagorevski DV; Linhardt RJ
• Enzymatic synthesis of heparin related polysaccharides on sensor chips: rapid screening of heparin-protein interactions.
  Biochem Biophys Res Commun Volume: 339 Page(s): 597 - 602
  01/13/2006 Authors: Muoz E; Xu D; Avci F; Kemp M; Liu J; Linhardt RJ
• CS lyases: structure, activity, and applications in analysis and the treatment of diseases.
  Volume: 53 Page(s): 187 - 215
  01/01/2006 Authors: Linhardt RJ; Avci FY; Toida T; Kim YS; Cygler M
• Enzymatic redesigning of biologically active heparan sulfate.
  J Biol Chem Volume: 280 Page(s): 42817 - 42825
  12/30/2005 Authors: Chen J; Avci FY; Muoz EM; McDowell LM; Chen M; Pedersen LC; Zhang L; Linhardt RJ; Liu J
• Preparation of the methyl ester of hyaluronan and its enzymatic degradation.
  Carbohydr Res Volume: 340 Page(s): 2297 - 2304
  10/17/2005 Authors: Hirano K; Sakai S; Ishikawa T; Avci FY; Linhardt RJ; Toida T
• Trifluoroethylsulfonate protected monosaccharides in glycosylation reactions.
  Volume: 228 Page(s): U219 - U219
  08/22/2004 Authors: Avci FY; Karst NA; Islam TF; Linhardt RJ
• Chondroitin O-methyl ester: an unusual substrate for chondroitin AC lyase.
  Carbohydr Res Volume: 338 Page(s): 2101 - 2104
  09/26/2003 Authors: Avci FY; Toida T; Linhardt RJ
• Disaccharide approach for the synthesis of glycosaminoglycan oligosaccharides.
  Volume: 226 Page(s): U200 - U200
  09/01/2003 Authors: Islam TF; Avci FY; Karst NA; Zhang JZ; Linhardt RJ
• Synthetic oligosaccharides as heparin-mimetics displaying anticoagulant properties.
  Curr Pharm Des Volume: 9 Page(s): 2323 - 2335
  01/01/2003 Authors: Avci FY; Karst NA; Linhardt RJ