School of Medicine Homepage
Emory University Shield
  • About
    • Our Vision
    • Academic Departments
    • Our Leadership
    • Health Care Partnerships
    • Diversity, Equity, & Inclusion
    • Location
    • Supporting Our People
    • Our Faculty
    • History
    • News
    • Events
    • Contact Us
  • Education
    • Degree and Certificate Programs
    • Academic Departments
    • Residents & Fellows
    • Postdoctoral Training
    • Continuing Medical Education
    • Admissions
    • Cost and Financial Aid
    • Student Resources
  • Research
    • Research Innovation
    • Conducting Research
    • Core Facilities
    • Research Centers
    • Research Training
    • Academic Departments
    • Find a Researcher
    • Research News
  • Clinical Experience
    • Where We Work
    • Caring for a Diverse Population
    • Faculty Clinical Experience
    • Advanced Patient Care
    • Academic Departments
    • Community Learning
  • Giving
  • Directory

Directory section navigation

  • Faculty Profiles

Emory University School of Medicine

  • About
    • Sub link
      Our Vision
    • Sub link
      Academic Departments
    • Sub link
      Our Leadership
    • Sub link
      Health Care Partnerships
    • Sub link
      Diversity, Equity, & Inclusion
    • Sub link
      Location
    • Sub link
      Supporting Our People
    • Sub link
      Our Faculty
    • Sub link
      History
    • Sub link
      News
    • Sub link
      Events
    • Sub link
      Contact Us
  • Education
    • Sub link
      Degree and Certificate Programs
    • Sub link
      Academic Departments
    • Sub link
      Residents & Fellows
    • Sub link
      Postdoctoral Training
    • Sub link
      Continuing Medical Education
    • Sub link
      Admissions
    • Sub link
      Cost and Financial Aid
    • Sub link
      Student Resources
  • Research
    • Sub link
      Research Innovation
    • Sub link
      Conducting Research
    • Sub link
      Core Facilities
    • Sub link
      Research Centers
    • Sub link
      Research Training
    • Sub link
      Academic Departments
    • Sub link
      Find a Researcher
    • Sub link
      Research News
  • Clinical Experience
    • Sub link
      Where We Work
    • Sub link
      Caring for a Diverse Population
    • Sub link
      Faculty Clinical Experience
    • Sub link
      Advanced Patient Care
    • Sub link
      Academic Departments
    • Sub link
      Community Learning
  • Giving
  • Directory
  • Home School of Medicine Home
  • Directory

Profile

Zunyan Dai PhD

  • Department of Human Genetics
    Adjunct Assistant Professor
  • (470) 378-2170
  • zunyan.dai@emory.edu

Research

Publications

  • Caution in interpretation of disease causality for heterozygous loss-of-function variants in the MYH8 gene associated with autosomal dominant disorder.
    Eur J Med Genet Volume: 60 Page(s): 312 - 316
    06/01/2017 Authors: Dai Z; Whitt Z; Mighion LC; Pontoglio A; Bean LJH; Colombo R; Hegde M
  • Paternal duplication of the 11p15 centromeric imprinting control region is associated with increased expression of CDKN1C in a child with Russell-Silver syndrome.
    Am J Med Genet A Volume: 167A Page(s): 3229 - 3233
    12/01/2015 Authors: Xue Y; Shankar S; Cornell K; Dai Z; Wang C-E; Rudd MK; Coffee B
  • Next-Generation Sequencing as a Diagnostic Tool for Hereditary Breast and Ovarian Cancer
    Volume: 17 Page(s): 761 - 761
    11/01/2015 Authors: Dai Z; Bean LJ; Collins C; Askree SH; Alexander JJ; Hegde M; Tanner A
  • Chromothriptic cure of WHIM syndrome.
    Cell Volume: 160 Page(s): 686 - 699
    02/12/2015 Authors: McDermott DH; Gao J-L; Liu Q; Siwicki M; Martens C; Jacobs P; Velez D; Yim E; Bryke CR; Hsu N
  • Haploinsufficiency of HDAC4 does not cause intellectual disability in all affected individuals.
    Am J Med Genet A Volume: 164A Page(s): 1826 - 1829
    07/01/2014 Authors: Wheeler PG; Huang D; Dai Z
  • Incidental Copy Number Findings in Targeted Microarray Gene Testing Explain Clinical Phenotypes
    Volume: 142
    01/01/2014 Authors: Dai Z; Bunke B; Kunig D; Vena NA; Bean LJH; Collins C; Coffee B; Rudd MK
  • Deletions of the PRKAR1A locus at 17q24.2-q24.3 in Carney complex: genotype-phenotype correlations and implications for genetic testing.
    J Clin Endocrinol Metab Volume: 99 Page(s): E183 - E188
    01/01/2014 Authors: Salpea P; Horvath A; London E; Faucz FR; Vetro A; Levy I; Gourgari E; Dauber A; Holm IA; Morrison PJ
  • Incidence and patterns of ALK FISH abnormalities seen in a large unselected series of lung carcinomas.
    Mol Cytogenet Volume: 5 Page(s): 44
    12/03/2012 Authors: Dai Z; Kelly JC; Meloni-Ehrig A; Slovak ML; Boles D; Christacos NC; Bryke CR; Schonberg SA; Otani-Rosa J; Pan Q
  • A common spinal muscular atrophy deletion mutation is present on a single founder haplotype in the US Hutterites.
    Eur J Hum Genet Volume: 19 Page(s): 1045 - 1051
    10/01/2011 Authors: Chong JX; Oktay AA; Dai Z; Swoboda KJ; Prior TW; Ober C
  • Flavopiridol pharmacogenetics: clinical and functional evidence for the role of SLCO1B1/OATP1B1 in flavopiridol disposition.
    PLoS One Volume: 5 Page(s): e13792
    11/01/2010 Authors: Ni W; Ji J; Dai Z; Papp A; Johnson AJ; Ahn S; Farley KL; Lin TS; Dalton JT; Li X
  • A multi-institutional phase II study of the efficacy and tolerability of lapatinib in patients with advanced hepatocellular carcinomas.
    Clin Cancer Res Volume: 15 Page(s): 5895 - 5901
    09/15/2009 Authors: Bekaii-Saab T; Markowitz J; Prescott N; Sadee W; Heerema N; Wei L; Dai Z; Papp A; Campbell A; Culler K
  • Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues.
    Pharmacogenet Genomics Volume: 18 Page(s): 781 - 791
    09/01/2008 Authors: Johnson AD; Zhang Y; Papp AC; Pinsonneault JK; Lim J-E; Saffen D; Dai Z; Wang D; Sade W
  • Genotyping panel for assessing response to cancer chemotherapy.
    BMC Med Genomics Volume: 1 Page(s): 24
    06/11/2008 Authors: Dai Z; Papp AC; Wang D; Hampel H; Sadee W
  • MicroRNAs modulate the chemosensitivity of tumor cells.
    Mol Cancer Ther Volume: 7 Page(s): 1 - 9
    01/01/2008 Authors: Blower PE; Chung J-H; Verducci JS; Lin S; Park J-K; Dai Z; Liu C-G; Schmittgen TD; Reinhold WC; Croce CM
  • Cystine-glutamate transporter SLC7A11 mediates resistance to geldanamycin but not to 17-(allylamino)-17-demethoxygeldanamycin.
    Mol Pharmacol Volume: 72 Page(s): 1637 - 1646
    12/01/2007 Authors: Liu R; Blower PE; Pham A-N; Fang J; Dai Z; Wise C; Green B; Teitel CH; Ning B; Ling W
  • Restriction landmark genomic scanning (RLGS) spot identification by second generation virtual RLGS in multiple genomes with multiple enzyme combinations.
    BMC Genomics Volume: 8 Page(s): 446
    11/30/2007 Authors: Smiraglia DJ; Kazhiyur-Mannar R; Oakes CC; Wu Y-Z; Liang P; Ansari T; Su J; Rush LJ; Smith LT; Yu L
  • Chemogenomic analysis identifies geldanamycins as substrates and inhibitors of ABCB1.
    Pharm Res Volume: 24 Page(s): 1702 - 1712
    09/01/2007 Authors: Huang Y; Blower PE; Liu R; Dai Z; Pham A-N; Moon H; Fang J; Sade W
  • MicroRNA expression profiles for the NCI-60 cancer cell panel.
    Mol Cancer Ther Volume: 6 Page(s): 1483 - 1491
    05/01/2007 Authors: Blower PE; Verducci JS; Lin S; Zhou J; Chung J-H; Dai Z; Liu C-G; Reinhold W; Lorenzi PL; Kaldjian EP
  • Chemoinformatics analysis identifies cytotoxic compounds susceptible to chemoresistance mediated by glutathione and cystine/glutamate transport system xc-.
    J Med Chem Volume: 50 Page(s): 1896 - 1906
    04/19/2007 Authors: Dai Z; Huang Y; Sadee W; Blower P
  • Glucose uptake inhibitor sensitizes cancer cells to daunorubicin and overcomes drug resistance in hypoxia.
    Cancer Chemother Pharmacol Volume: 59 Page(s): 495 - 505
    03/01/2007 Authors: Cao X; Fang L; Gibbs S; Huang Y; Dai Z; Wen P; Zheng X; Sadee W; Sun D
  • 5-Aza-2'-deoxycytidine and depsipeptide synergistically induce expression of BIK (BCL2-interacting killer).
    Biochem Biophys Res Commun Volume: 351 Page(s): 455 - 461
    12/15/2006 Authors: Dai Z; Liu S; Marcucci G; Sadee W
  • Prediction of anticancer drug potency from expression of genes involved in growth factor signaling.
    Pharm Res Volume: 23 Page(s): 336 - 349
    02/01/2006 Authors: Dai Z; Barbacioru C; Huang Y; Sade W
  • A pharmacoproteomics study of the cancer cell line EKVX using capillary-LC/MS/MS.
    Mol Pharm Volume: 3 Page(s): 566 - 578
    01/01/2006 Authors: Wang Y; Dai Z; Sadee W; Hancock WS
  • Pharmacogenetics/genomics and personalized medicine.
    Hum Mol Genet Volume: 14 Spec No. 2 Page(s): R207 - R214
    10/15/2005 Authors: Sade W; Dai Z
  • Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance.
    Cancer Res Volume: 65 Page(s): 7446 - 7454
    08/15/2005 Authors: Huang Y; Dai Z; Barbacioru C; Sade W
  • Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines.
    J Pharmacol Exp Ther Volume: 314 Page(s): 467 - 475
    07/01/2005 Authors: Xiao JJ; Huang Y; Dai Z; Sade W; Chen J; Liu S; Marcucci G; Byrd J; Covey JM; Wright J
  • Efflux of depsipeptide FK228 (FR901228, NSC-630176) is mediated by P-glycoprotein and multidrug resistance-associated protein 1.
    J Pharmacol Exp Ther Volume: 313 Page(s): 268 - 276
    04/01/2005 Authors: Xiao JJ; Foraker AB; Swaan PW; Liu S; Huang Y; Dai Z; Chen J; Sade W; Byrd J; Marcucci G
  • Global assessment of promoter methylation in a mouse model of cancer identifies ID4 as a putative tumor-suppressor gene in human leukemia.
    Nat Genet Volume: 37 Page(s): 265 - 274
    03/01/2005 Authors: Yu L; Liu C; Vandeusen J; Becknell B; Dai Z; Wu Y-Z; Raval A; Liu T-H; Ding W; Mao C
  • Correlating gene expression with chemical scaffolds of cytotoxic agents: ellipticines as substrates and inhibitors of MDR1.
    Pharmacogenomics J Volume: 5 Page(s): 112 - 125
    01/01/2005 Authors: Huang Y; Blower PE; Yang C; Barbacioru C; Dai Z; Zhang Y; Xiao JJ; Chan KK; Sade W
  • A NotI-EcoRV promoter library for studies of genetic and epigenetic alterations in mouse models of human malignancies.
    Genomics Volume: 84 Page(s): 647 - 660
    10/01/2004 Authors: Yu L; Liu C; Bennett K; Wu Y-Z; Dai Z; Vandeusen J; Opavsky R; Raval A; Trikha P; Rodriguez B
  • Membrane transporters and channels: role of the transportome in cancer chemosensitivity and chemoresistance.
    Cancer Res Volume: 64 Page(s): 4294 - 4301
    06/15/2004 Authors: Huang Y; Anderle P; Bussey KJ; Barbacioru C; Shankavaram U; Dai Z; Reinhold WC; Papp A; Weinstein JN; Sade W
  • Bone morphogenetic protein 3B silencing in non-small-cell lung cancer.
    Oncogene Volume: 23 Page(s): 3521 - 3529
    04/29/2004 Authors: Dai Z; Popkie AP; Zhu W-G; Timmers CD; Raval A; Tannehill-Gregg S; Morrison CD; Auer H; Kratzke RA; Niehans G
  • 5-aza-2'-deoxycytidine activates the p53/p21Waf1/Cip1 pathway to inhibit cell proliferation.
    J Biol Chem Volume: 279 Page(s): 15161 - 15166
    04/09/2004 Authors: Zhu W-G; Hileman T; Ke Y; Wang P; Lu S; Duan W; Dai Z; Tong T; Villalona-Calero MA; Plass C
  • Growth factor signaling and resistance to cancer chemotherapy.
    Curr Top Med Chem Volume: 4 Page(s): 1347 - 1356
    01/01/2004 Authors: Dai Z; Huang Y; Sade W
  • Methylation of adjacent CpG sites affects Sp1/Sp3 binding and activity in the p21(Cip1) promoter.
    Mol Cell Biol Volume: 23 Page(s): 4056 - 4065
    06/01/2003 Authors: Zhu W-G; Srinivasan K; Dai Z; Duan W; Druhan LJ; Ding H; Yee L; Villalona-Calero MA; Plass C; Otterson GA
  • A comprehensive search for DNA amplification in lung cancer identifies inhibitors of apoptosis cIAP1 and cIAP2 as candidate oncogenes.
    Hum Mol Genet Volume: 12 Page(s): 791 - 801
    04/01/2003 Authors: Dai Z; Zhu W-G; Morrison CD; Brena RM; Smiraglia DJ; Raval A; Wu Y-Z; Rush LJ; Ross P; Molina JR
  • LOH of chromosome 12p correlates with Kras2 mutation in non-small cell lung cancer.
    Oncogene Volume: 22 Page(s): 1243 - 1246
    02/27/2003 Authors: Li J; Zhang Z; Dai Z; Plass C; Morrison C; Wang Y; Wiest JS; Anderson MW; You M
  • Differential targets of CpG island hypermethylation in primary and metastatic head and neck squamous cell carcinoma (HNSCC).
    J Med Genet Volume: 40 Page(s): 25 - 33
    01/01/2003 Authors: Smiraglia DJ; Smith LT; Lang JC; Rush LJ; Dai Z; Schuller DE; Plass C
  • An AscI boundary library for the studies of genetic and epigenetic alterations in CpG islands.
    Genome Res Volume: 12 Page(s): 1591 - 1598
    10/01/2002 Authors: Dai Z; Weichenhan D; Wu Y-Z; Hall JL; Rush LJ; Smith LT; Raval A; Yu L; Kroll D; Muehlisch J
  • Increased expression of unmethylated CDKN2D by 5-aza-2'-deoxycytidine in human lung cancer cells.
    Oncogene Volume: 20 Page(s): 7787 - 7796
    11/22/2001 Authors: Zhu WG; Dai Z; Ding H; Srinivasan K; Hall J; Duan W; Villalona-Calero MA; Plass C; Otterson GA
  • Aberrant promoter methylation of previously unidentified target genes is a common abnormality in medulloblastomas--implications for tumor biology and potential clinical utility.
    Oncogene Volume: 20 Page(s): 5033 - 5042
    08/16/2001 Authors: Frhwald MC; O'Dorisio MS; Dai Z; Tanner SM; Balster DA; Gao X; Wright FA; Plass C
  • Excessive CpG island hypermethylation in cancer cell lines versus primary human malignancies.
    Hum Mol Genet Volume: 10 Page(s): 1413 - 1419
    06/15/2001 Authors: Smiraglia DJ; Rush LJ; Frhwald MC; Dai Z; Held WA; Costello JF; Lang JC; Eng C; Li B; Wright FA
  • Novel methylation targets in de novo acute myeloid leukemia with prevalence of chromosome 11 loci.
    Blood Volume: 97 Page(s): 3226 - 3233
    05/15/2001 Authors: Rush LJ; Dai Z; Smiraglia DJ; Gao X; Wright FA; Frhwald M; Costello JF; Held WA; Yu L; Krahe R
  • Global methylation profiling of lung cancer identifies novel methylated genes.
    Neoplasia Volume: 3 Page(s): 314 - 323
    01/01/2001 Authors: Dai Z; Lakshmanan RR; Zhu WG; Smiraglia DJ; Rush LJ; Frhwald MC; Brena RM; Li B; Wright FA; Ross P
  • Aberrant hypermethylation of the major breakpoint cluster region in 17p11.2 in medulloblastomas but not supratentorial PNETs.
    Genes Chromosomes Cancer Volume: 30 Page(s): 38 - 47
    01/01/2001 Authors: Frhwald MC; O'Dorisio MS; Dai Z; Rush LJ; Krahe R; Smiraglia DJ; Pietsch T; Elsea SH; Plass C
  • [Hypermethylation as a potential prognostic factor and a clue to a better understanding of the molecular pathogenesis of medulloblastoma--results of a genomewide methylation scan].
    Klin Padiatr Volume: 213 Page(s): 197 - 203
    01/01/2001 Authors: Frhwald MC; O'Dorisio MS; Smith L; Dai Z; Wright FA; Paulus W; Jrgens H; Plass C
  • A new tool for the rapid cloning of amplified and hypermethylated human DNA sequences from restriction landmark genome scanning gels.
    Genomics Volume: 58 Page(s): 254 - 262
    06/15/1999 Authors: Smiraglia DJ; Frhwald MC; Costello JF; McCormick SP; Dai Z; Peltomki P; O'Dorisio MS; Cavenee WK; Plass C
Read more publications Fewer publications
Directory
  • Faculty Profiles
Emory University Homepage

Contact & Location

Emory University School of Medicine
100 Woodruff Circle
Atlanta, GA  30322 USA
  • Contact Us
  • Maps & Directions
  • Careers

Information For

  • Alumni
  • Faculty & Staff
  • Patients
  • Residents & Fellows
  • Students
Support the School of Medicine School of Medicine Intranet
facebook facebook twitter twitter linkedin linkedin instagram instagram youtube youtube
© 2025 Emory University
  • Privacy Policy
  • Emergency Information
  • EEO Employer-Disability/Veteran Statements