Yesim Polar
- Department of Pathology and Laboratory Medicine
Associate Professor
- (404) 727-8998
- ypolar@emory.edu
- My Porfolio
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Emory University School of Medicine
Pathology and Laboratory Medicine
Emory Winship Cancer Institute, 1365 E Clifton RD NE, C3080
Overview
Dr. Polar (Gkmen-Polar) 's research focuses on the identification of novel targets for therapy- resistant breast cancer leading to the development of targeted therapies. She has established laboratory models for acquired resistance in breast cancer and thymic malignancies, which has allowed for both identification of novel targets and validation of novel targeted therapies and provided the basis for clinical trials of novel therapeutics.
She has developed, validated, and patented gene signatures for Thymoma and Breast cancer.
Academic Appointment
- Associate Professor, Emory Laney Graduate School, Cancer Biology Graduate Program (CB), Graduate Division of Biological , Emory University
- Associate Professor, Pathology and Laboratory Medicine, Emory University School of Medicine
- Associate Director, Pathology Cancer Program, Pathology and Laboratory Medicine, Emory University School of Medicine
Education
Degrees
- PhD from Bogazici University, Molecular Biology and Genetics
- MS from Bogazici University
Research
Publications
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MorphLink: Bridging Cell Morphological Behaviors and Molecular Dynamics in Multi-modal Spatial Omics.
bioRxiv
08/26/2024 Authors: Huang J; Yuan C; Jiang J; Chen J; Badve SS; Gokmen-Polar Y; Segura RL; Yan X; Lazar A; Gao J -
Triple Negative Breast Cancers: An Obsolete Entity?
Clin Breast Cancer Volume: 24 Page(s): 1 - 6
01/01/2024 Authors: Keskinklc M; Gkmen-Polar Y; Badve SS -
Dual Prognostic Classification of Triple-Negative Breast Cancer by DNA Damage Immune Response and Homologous Recombination Deficiency.
JCO Precis Oncol Volume: 7 Page(s): e2300197
09/01/2023 Authors: Stecklein SR; Barlow W; Pusztai L; Timms K; Kennedy R; Logan GE; Seitz R; Badve S; Gkmen-Polar Y; Porter P -
Genome-scale metabolic modeling suggests novel molecular targets in ER-positive breast cancer
Volume: 83
04/01/2023 Authors: Mudge ZB; Kovacs K; Kemp ML; Badve SS; Gokmen-Polar Y -
Predicting Breast Cancer Events in Ductal Carcinoma In Situ (DCIS) Using Generative Adversarial Network Augmented Deep Learning Model.
Cancers (Basel) Volume: 15
03/23/2023 Authors: Ghose S; Cho S; Ginty F; McDonough E; Davis C; Zhang Z; Mitra J; Harris AL; Thike AA; Tan PH -
A predictor of response in HER2+ breast cancer-at last!
J Natl Cancer Inst Volume: 115 Page(s): 242 - 245
03/09/2023 Authors: Badve SS; Gkmen-Polar Y -
The Role of ESRP1 in the Regulation of PHGDH in Estrogen Receptor-Positive Breast Cancer.
Lab Invest Volume: 103 Page(s): 100002
03/01/2023 Authors: Gkmen-Polar Y; Gu Y; Polar A; Gu X; Badve SS -
Targeting the Tumor-Tumor Microenvironment Crosstalk.
Expert Opin Ther Targets Volume: 27 Page(s): 447 - 457
01/01/2023 Authors: Badve SS; Gkmen-Polar Y -
Spatially variant immune infiltration scoring in human cancer tissues.
NPJ Precis Oncol Volume: 6 Page(s): 60
09/01/2022 Authors: Allam M; Hu T; Lee J; Aldrich J; Badve SS; Gkmen-Polar Y; Bhave M; Ramalingam SS; Schneider F; Coskun AF -
Tumor Infiltrating Lymphocytes in Multi-National Cohorts of Ductal Carcinoma In Situ (DCIS) of Breast.
Cancers (Basel) Volume: 14
08/13/2022 Authors: Badve SS; Cho S; Lu X; Cao S; Ghose S; Thike AA; Tan PH; Ocal IT; Generali D; Zanconati F