School of Medicine Homepage
Emory University Shield
  • About
    • Our Vision
    • Academic Departments
    • Our Leadership
    • Health Care Partnerships
    • Diversity, Equity, & Inclusion
    • Location
    • Supporting Our People
    • Our Faculty
    • History
    • News
    • Events
    • Contact Us
  • Education
    • Degree and Certificate Programs
    • Academic Departments
    • Residents & Fellows
    • Postdoctoral Training
    • Continuing Medical Education
    • Admissions
    • Cost and Financial Aid
    • Student Resources
  • Research
    • Research Innovation
    • Conducting Research
    • Core Facilities
    • Research Centers
    • Research Training
    • Academic Departments
    • Find a Researcher
    • Research News
  • Clinical Experience
    • Where We Work
    • Caring for a Diverse Population
    • Faculty Clinical Experience
    • Advanced Patient Care
    • Academic Departments
    • Community Learning
  • Giving
  • Directory

Directory section navigation

  • Faculty Profiles

Emory University School of Medicine

  • About
    • Sub link
      Our Vision
    • Sub link
      Academic Departments
    • Sub link
      Our Leadership
    • Sub link
      Health Care Partnerships
    • Sub link
      Diversity, Equity, & Inclusion
    • Sub link
      Location
    • Sub link
      Supporting Our People
    • Sub link
      Our Faculty
    • Sub link
      History
    • Sub link
      News
    • Sub link
      Events
    • Sub link
      Contact Us
  • Education
    • Sub link
      Degree and Certificate Programs
    • Sub link
      Academic Departments
    • Sub link
      Residents & Fellows
    • Sub link
      Postdoctoral Training
    • Sub link
      Continuing Medical Education
    • Sub link
      Admissions
    • Sub link
      Cost and Financial Aid
    • Sub link
      Student Resources
  • Research
    • Sub link
      Research Innovation
    • Sub link
      Conducting Research
    • Sub link
      Core Facilities
    • Sub link
      Research Centers
    • Sub link
      Research Training
    • Sub link
      Academic Departments
    • Sub link
      Find a Researcher
    • Sub link
      Research News
  • Clinical Experience
    • Sub link
      Where We Work
    • Sub link
      Caring for a Diverse Population
    • Sub link
      Faculty Clinical Experience
    • Sub link
      Advanced Patient Care
    • Sub link
      Academic Departments
    • Sub link
      Community Learning
  • Giving
  • Directory
  • Home School of Medicine Home
  • Directory

Profile

Xuemin Chen MD

  • Department of Pediatrics
    Assistant Professor
  • (404) 727-9230
  • xchen26@emory.edu
Head shot of Xuemin Chen

Academic Appointment

Education

Degrees

  • M.S. from Xi'an Medical University
  • MD from Xi'an Medical University

Research

Publications

  • Fc-effector functional antibody assays for SARS-CoV-2 variants of concern.
    Front Immunol Volume: 16 Page(s): 1571835
    01/01/2025 Authors: Chen X; Li G; Ciric C; Gibson T; Anderson LJ; Rostad CA
  • A Phase 1 randomized trial of homologous and heterologous filovirus vaccines with a late booster dose.
    NPJ Vaccines Volume: 9 Page(s): 255
    12/23/2024 Authors: Rostad CA; Yildirim I; Kao C; Yi J; Kamidani S; Peters E; Stephens K; Gibson T; Hsiao H-M; Singh K
  • SARS-CoV-2 Antibody Profiles in Maternal Serum and Breast Milk Following mRNA COVID-19 Vaccination: A Longitudinal Prospective Observational Cohort Study.
    Vaccines (Basel) Volume: 11
    10/26/2023 Authors: Hsiao H-M; DiMaggio LS; Perez MA; Chen X; Stephens K; Gibson T; Anderson EJ; Rostad CA
  • Serologic responses to COVID-19 vaccination in children with history of multisystem inflammatory syndrome (MIS-C).
    Vaccine Volume: 41 Page(s): 2743 - 2748
    04/24/2023 Authors: Perez MA; Hsiao H-M; Chen X; Kunkel A; Baida N; Hussaini L; Lu AT; Kao CM; Laham FR; Hunstad DA
  • Longitudinal Neutralizing and Functional Antibody Responses to Severe Acute Respiratory Syndrome Coronavirus 2 Variants Following Messenger RNA Coronavirus Disease 2019 Vaccination.
    Open Forum Infect Dis Volume: 10 Page(s): ofad167
    04/01/2023 Authors: Chen X; Ciric C; Gibson T; Anderson LJ; Anderson EJ; Rostad CA
  • An RSV Live-Attenuated Vaccine Candidate Lacking G Protein Mucin Domains Is Attenuated, Immunogenic, and Effective in Preventing RSV in BALB/c Mice.
    J Infect Dis Volume: 227 Page(s): 50 - 60
    12/28/2022 Authors: Roe MK; Perez MA; Hsiao H-M; Lapp SA; Sun H-Y; Jadhao S; Young AR; Batista YS; Reed RC; Taz A
  • Functional Antibody Responses to Severe Acute Respiratory Syndrome Coronavirus 2 Variants in Children With Coronavirus Disease 2019, Multisystem Inflammatory Syndrome in Children, and After Two Doses of BNT162b2 Vaccination.
    J Infect Dis Volume: 226 Page(s): 1237 - 1242
    09/28/2022 Authors: Rostad CA; Chen X; Sun HY; Hussaini L; Lu A; Perez MA; Hsiao HM; Anderson LJ; Anderson EJ
  • Functional antibody-dependent cell mediated cytotoxicity (ADCC) responses to vaccine and circulating influenza strains following vaccination.
    Virology Volume: 569 Page(s): 44 - 55
    04/01/2022 Authors: Chen X; Sun H-Y; Lee CY; Rostad CA; Trost J; Abreu RB; Carlock MA; Wilson JR; Gansebom S; Ross TM
  • The development and kinetics of functional antibody-dependent cell-mediated cytotoxicity (ADCC) to SARS-CoV-2 spike protein.
    Virology Volume: 559 Page(s): 1 - 9
    07/01/2021 Authors: Chen X; Rostad CA; Anderson LJ; Sun H-Y; Lapp SA; Stephens K; Hussaini L; Gibson T; Rouphael N; Anderson EJ
  • Development and optimization of a Zika virus antibody-dependent cell-mediated cytotoxicity (ADCC) assay.
    J Immunol Methods Volume: 488 Page(s): 112900
    01/01/2021 Authors: Chen X; Anderson LJ; Rostad CA; Ding L; Lai L; Mulligan M; Rouphael N; Natrajan MS; McCracken C; Anderson EJ
  • Parainfluenza Virus 5 Priming Followed by SIV/HIV Virus-Like-Particle Boosting Induces Potent and Durable Immune Responses in Nonhuman Primates.
    Front Immunol Volume: 12 Page(s): 623996
    01/01/2021 Authors: Xiao P; Dienger-Stambaugh K; Chen X; Wei H; Phan S; Beavis AC; Singh K; Adhikary NRD; Tiwari P; Villinger F
  • Two RSV Platforms for G, F, or G+F Proteins VLPs.
    Viruses Volume: 12
    08/19/2020 Authors: Ha B; Yang JE; Chen X; Jadhao SJ; Wright ER; Anderson LJ
  • A Bivalent, Spherical Virus-Like Particle Vaccine Enhances Breadth of Immune Responses against Pathogenic Ebola Viruses in Rhesus Macaques.
    J Virol Volume: 94
    04/16/2020 Authors: Singh K; Marasini B; Chen X; Ding L; Wang J-J; Xiao P; Villinger F; Spearman P
  • A novel Ebola virus antibody-dependent cell-mediated cytotoxicity (Ebola ADCC) assay.
    J Immunol Methods Volume: 460 Page(s): 10 - 16
    09/01/2018 Authors: Singh K; Marasini B; Chen X; Spearman P
  • Adjuvanting a Simian Immunodeficiency Virus Vaccine with Toll-Like Receptor Ligands Encapsulated in Nanoparticles Induces Persistent Antibody Responses and Enhanced Protection in TRIM5 Restrictive Macaques.
    J Virol Volume: 91
    02/15/2017 Authors: Kasturi SP; Kozlowski PA; Nakaya HI; Burger MC; Russo P; Pham M; Kovalenkov Y; Silveira ELV; Havenar-Daughton C; Burton SL
  • Low frequency of broadly neutralizing HIV antibodies during chronic infection even in quaternary epitope targeting antibodies containing large numbers of somatic mutations.
    Mol Immunol Volume: 70 Page(s): 94 - 103
    02/01/2016 Authors: Hicar MD; Chen X; Kalams SA; Sojar H; Landucci G; Forthal DN; Spearman P; Crowe JE
  • Human Antibodies that Recognize Novel Immunodominant Quaternary Epitopes on the HIV-1 Env Protein.
    PLoS One Volume: 11 Page(s): e0158861
    01/01/2016 Authors: Hicar MD; Chen X; Sulli C; Barnes T; Goodman J; Sojar H; Briney B; Willis J; Chukwuma VU; Kalams SA
  • HIV-specific CD4-induced Antibodies Mediate Broad and Potent Antibody-dependent Cellular Cytotoxicity Activity and Are Commonly Detected in Plasma From HIV-infected humans.
    EBioMedicine Volume: 2 Page(s): 1464 - 1477
    10/01/2015 Authors: Williams KL; Cortez V; Dingens AS; Gach JS; Rainwater S; Weis JF; Chen X; Spearman P; Forthal DN; Overbaugh J
  • Association of VH4-59 Antibody Variable Gene Usage with Recognition of an Immunodominant Epitope on the HIV-1 Gag Protein.
    PLoS One Volume: 10 Page(s): e0133509
    01/01/2015 Authors: Chukwuma VU; Hicar MD; Chen X; Nicholas KJ; Joyner A; Kalams SA; Landucci G; Forthal DN; Spearman PW; Crowe JE
  • B-cells that Bind HIV Particles Encode CD4-induced, C11-like and V3-specific Antibodies that Mediate Broad ADCC Activity.
    AIDS Res Hum Retroviruses Volume: 30 Suppl 1 Page(s): A193
    10/01/2014 Authors: Williams KL; Cortez V; Dingens AS; Rainwater S; Weis JF; Chen X; Spearman PW; Overbaugh J
  • Capturing enveloped viruses on affinity grids for downstream cryo-electron microscopy applications.
    Microsc Microanal Volume: 20 Page(s): 164 - 174
    02/01/2014 Authors: Kiss G; Chen X; Brindley MA; Campbell P; Afonso CL; Ke Z; Holl JM; Guerrero-Ferreira RC; Byrd-Leotis LA; Steel J
  • Nanoparticle Based Delivery of TLR4 and TLR7/8 Ligands with SIV Envelope Immunogens Induce Systemic and Mucosal Humoral Immunity in Rhesus Macaques
    Volume: 29 Page(s): A27 - A27
    11/01/2013 Authors: Kasturi SP; Wrammert J; Pham M; Xiao P; Kovalenkov Y; Chen X; Johnson MJ; Hunter E; Kozlowski PA; Villinger F
  • Different pattern of immunoglobulin gene usage by HIV-1 compared to non-HIV-1 antibodies derived from the same infected subject.
    PLoS One Volume: 7 Page(s): e39534
    01/01/2012 Authors: Li L; Wang X-H; Banerjee S; Volsky B; Williams C; Virland D; Nadas A; Seaman MS; Chen X; Spearman P
  • Humoral response to recombinant, hypoglycosylated gp120 antigens in mouse models
    Volume: 26 Page(s): A166 - A166
    10/01/2010 Authors: Takezaki M; Chen X; Gamble D; Bolduc A; Shimoda M; Spearman P; Koni PA
  • Characterization of optimized virus-like particles bearing various forms of HIV-1 clade B envelope protein
    Volume: 26 Page(s): A126 - A126
    10/01/2010 Authors: Chen X; Xing M; Spearman P
  • Cloning of Quaternary Specific Antibodies
    Volume: 26 Page(s): A54 - A55
    10/01/2010 Authors: Hicar MD; Chen X; Briney B; Willis J; Kalams S; Spearman P; Crowe JE
  • Pseudovirion particles bearing native HIV envelope trimers facilitate a novel method for generating human neutralizing monoclonal antibodies against HIV.
    J Acquir Immune Defic Syndr Volume: 54 Page(s): 223 - 235
    07/01/2010 Authors: Hicar MD; Chen X; Briney B; Hammonds J; Wang J-J; Kalams S; Spearman PW; Crowe JE
  • Advances in methods for the production, purification, and characterization of HIV-1 Gag-Env pseudovirion vaccines.
    Vaccine Volume: 25 Page(s): 8036 - 8048
    11/19/2007 Authors: Hammonds J; Chen X; Zhang X; Lee F; Spearman P
  • Induction of neutralizing antibodies against human immunodeficiency virus type 1 primary isolates by Gag-Env pseudovirion immunization.
    J Virol Volume: 79 Page(s): 14804 - 14814
    12/01/2005 Authors: Hammonds J; Chen X; Fouts T; DeVico A; Montefiori D; Spearman P
  • Pseudovirion particle production by live poxvirus human immunodeficiency virus vaccine vector enhances humoral and cellular immune responses.
    J Virol Volume: 79 Page(s): 5537 - 5547
    05/01/2005 Authors: Chen X; Rock MT; Hammonds J; Tartaglia J; Shintani A; Currier J; Slike B; Crowe JE; Marovich M; Spearman P
  • AP-3 directs the intracellular trafficking of HIV-1 Gag and plays a key role in particle assembly.
    Cell Volume: 120 Page(s): 663 - 674
    03/11/2005 Authors: Dong X; Li H; Derdowski A; Ding L; Burnett A; Chen X; Peters TR; Dermody TS; Woodruff E; Wang J-J
  • Genetic complementation in yeast reveals functional similarities between the catalytic subunits of mammalian signal peptidase complex.
    J Biol Chem Volume: 278 Page(s): 50932 - 50939
    12/19/2003 Authors: Liang H; VanValkenburgh C; Chen X; Mullins C; Van Kaer L; Green N; Fang H
  • Gp120 stability on HIV-1 virions and Gag-Env pseudovirions is enhanced by an uncleaved Gag core.
    Virology Volume: 314 Page(s): 636 - 649
    09/30/2003 Authors: Hammonds J; Chen X; Ding L; Fouts T; De Vico A; zur Megede J; Barnett S; Spearman P
  • Factors governing nonoverlapping substrate specificity by mitochondrial inner membrane peptidase.
    J Biol Chem Volume: 278 Page(s): 4943 - 4948
    02/14/2003 Authors: Luo W; Chen X; Fang H; Green N
  • Expression of vaccinia E3L and K3L genes by a novel recombinant canarypox HIV vaccine vector enhances HIV-1 pseudovirion production and inhibits apoptosis in human cells.
    Virology Volume: 291 Page(s): 272 - 284
    12/20/2001 Authors: Fang ZY; Limbach K; Tartaglia J; Hammonds J; Chen X; Spearman P
  • Signal peptidase and oligosaccharyltransferase interact in a sequential and dependent manner within the endoplasmic reticulum.
    J Biol Chem Volume: 276 Page(s): 2411 - 2416
    01/26/2001 Authors: Chen X; VanValkenburgh C; Liang H; Fang H; Green N
  • Signal peptides having standard and nonstandard cleavage sites can be processed by Imp1p of the mitochondrial inner membrane protease.
    J Biol Chem Volume: 274 Page(s): 37750 - 37754
    12/31/1999 Authors: Chen X; Van Valkenburgh C; Fang H; Green N
  • The catalytic mechanism of endoplasmic reticulum signal peptidase appears to be distinct from most eubacterial signal peptidases.
    J Biol Chem Volume: 274 Page(s): 11519 - 11525
    04/23/1999 Authors: VanValkenburgh C; Chen X; Mullins C; Fang H; Green N
Read more publications Fewer publications
Directory
  • Faculty Profiles
Emory University Homepage

Contact & Location

Emory University School of Medicine
100 Woodruff Circle
Atlanta, GA  30322 USA
  • Contact Us
  • Maps & Directions
  • Careers

Information For

  • Alumni
  • Faculty & Staff
  • Patients
  • Residents & Fellows
  • Students
Support the School of Medicine School of Medicine Intranet
facebook facebook twitter twitter linkedin linkedin instagram instagram youtube youtube
© 2025 Emory University
  • Privacy Policy
  • Emergency Information
  • EEO Employer-Disability/Veteran Statements