Wei Zhou PhD

Department of Hematology and Medical Oncology
Professor

(404) 778-2134
wzhou2@emory.edu

Emory University, Atlanta
Hematology and Medical Oncology
1365 Clifton Road NE

Academic Appointment

Professor, Department of Hematology and Medical Oncology, Emory University School of Medicine

Education

Degrees

PhD from Emory University School of Medicine
BS from Georgia State University

Research

Focus

The tumor genome is a dynamic, unstable entity. Among the numerous genetic alterations occur in tumors, only a few events lead to the activation of oncogenes or the inactivation of tumor suppressor genes, both of which are essential for tumor development. One of the greatest challenges in the field of cancer genetics is the identification of those specific mutations that spur tumorigenesis. We are interested in identifying such mutations to study the molecular basis of human cancer.

Publications

Smoking aggravates neovascular age-related macular degeneration via Sema4D-PlexinB1 axis-mediated activation of pericytes.
Nat Commun Volume: 16 Page(s): 2821
03/22/2025 Authors: He K; Dong X; Yang T; Li Z; Liu Y; He J; Wu M; Wei-Zhang S; Kaysar P; Cui B
Uncovering the rewired IAP-JAK regulatory axis as an immune-dependent vulnerability of LKB1-mutant lung cancer.
Nat Commun Volume: 16 Page(s): 2324
03/08/2025 Authors: Shu C; Li J; Rui J; Fan D; Niu Q; Bai R; Cicka D; Doyle S; Wahafu A; Zheng X
SPAGRM: effectively controlling for sample relatedness in large-scale genome-wide association studies of longitudinal traits.
Nat Commun Volume: 16 Page(s): 1413
02/06/2025 Authors: Xu H; Ma Y; Xu L-L; Li Y; Liu Y; Li Y; Zhou X-J; Zhou W; Lee S; Zhang P
Assessment of photoreceptor recovery and visual function utilizing adaptive optics and microperimetry in patients with surgically closed macular holes.
Photodiagnosis Photodyn Ther Volume: 51 Page(s): 104458
02/01/2025 Authors: Liu Y; Yang X; Zhou W; Yu J; Chen S; He T; You C; Meng X; Liao M; Lei Y
Live-Cell Invasive Phenotyping Uncovers ALK2 as a Therapeutic Target in LKB1-Mutant Lung Cancer.
Cancer Res Volume: 84 Page(s): 3761 - 3771
11/15/2024 Authors: Koo J; Seong C-S; Parker RE; Herrera A; Dwivedi B; Arthur RA; Dinasarapu AR; Johnston HR; Claussen H; Tucker-Burden C
Genome-wide meta-analysis conducted in three large biobanks expands the genetic landscape of lumbar disc herniations.
Nat Commun Volume: 15 Page(s): 9424
11/07/2024 Authors: Salo V; Mtt J; Sliz E; FinnGen; Reimann E; Mgi R; Estonian Biobank Research Team; Reis K; Elhanas AG; Reigo A
Evaluation of the relationship between the real-time changes of macular structure and visual function in patients with rhegmatogenous retinal detachment after silicone oil tamponade.
Photodiagnosis Photodyn Ther Volume: 49 Page(s): 104350
10/01/2024 Authors: Song J; Zhang H; Yang X; Yao X; Miao Y; Wang Q; Zhou F; Wang Y; Yu J; He K
Relationship between visual acuity and OCT angiography parameters in diabetic retinopathy eyes after treatment.
Eur J Ophthalmol Volume: 34 Page(s): 1521 - 1531
09/01/2024 Authors: Wei-Zhang S; He K; Zhou W; Yu J; Zhao J; He T; Chen S; Kaysar P; Sun Z; Jia D
Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.
Science Volume: 385 Page(s): eadj1182
07/19/2024 Authors: Verma A; Huffman JE; Rodriguez A; Conery M; Liu M; Ho Y-L; Kim Y; Heise DA; Guare L; Panickan VA
Author Correction: Nuclear genetic control of mtDNA copy number and heteroplasmy in humans.
Nature Volume: 630 Page(s): E10
06/01/2024 Authors: Gupta R; Kanai M; Durham TJ; Tsuo K; McCoy JG; Kotrys AV; Zhou W; Chinnery PF; Karczewski KJ; Calvo SE
Interruption of KLF5 acetylation promotes PTEN-deficient prostate cancer progression by reprogramming cancer-associated fibroblasts.
J Clin Invest Volume: 134
05/23/2024 Authors: Zhang B; Liu M; Mai F; Li X; Wang W; Huang Q; Du X; Ding W; Li Y; Barwick BG
A multi-ancestry genome-wide association study in type 1 diabetes.
Hum Mol Genet Volume: 33 Page(s): 958 - 968
05/18/2024 Authors: Michalek DA; Tern C; Zhou W; Robertson CC; Farber E; Campolieto P; Chen W-M; Onengut-Gumuscu S; Rich SS
A genome-wide association study provides insights into the genetic etiology of 57 essential and non-essential trace elements in humans.
Commun Biol Volume: 7 Page(s): 432
04/09/2024 Authors: Moksnes MR; Hansen AF; Wolford BN; Thomas LF; Rasheed H; Simi A; Bhatta L; Brantster AL; Surakka I; Zhou W
Recalled age of myopia onset may predict risk of high adult myopia in Chinese adults.
Ophthalmic Res
03/29/2024 Authors: Mao C; Zhang X; Liao M; Zhou F; Zhu X; Wang T; Xie R; Zhang H; Yang T; He K
Novel ancestry-specific primary open-angle glaucoma loci and shared biology with vascular mechanisms and cell proliferation.
Cell Rep Med Volume: 5 Page(s): 101430
02/20/2024 Authors: Lo Faro V; Bhattacharya A; Zhou W; Zhou D; Wang Y; Lll K; Kanai M; Lopera-Maya E; Straub P; Pawar P
Structural basis for transcription activation by the nitrate-responsive regulator NarL.
Nucleic Acids Res Volume: 52 Page(s): 1471 - 1482
02/09/2024 Authors: Kompaniiets D; He L; Wang D; Zhou W; Yang Y; Hu Y; Liu B
An integrated analysis identifies six molecular subtypes of pancreatic ductal adenocarcinoma revealing cellular and molecular landscape.
Carcinogenesis Volume: 44 Page(s): 726 - 740
12/15/2023 Authors: Li L; Shen L; Wu H; Li M; Chen L; Zhou Q; Ma J; Huai C; Zhou W; Wei M
A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains.
Nat Genet Volume: 55 Page(s): 2104 - 2116
12/01/2023 Authors: Sziraki A; Lu Z; Lee J; Banyai G; Anderson S; Abdulraouf A; Metzner E; Liao A; Banfelder J; Epstein A
Effects of Individual Amino Acids on the Blood Circulation of Biosynthetic Protein Nanocages: Toward Guidance on Surface Engineering.
Adv Healthc Mater Volume: 12 Page(s): e2300502
10/01/2023 Authors: Liang A; Zhou W; Zhang H; Zhang J; Zhang X-E; Fang T; Li F
A second update on mapping the human genetic architecture of COVID-19.
Nature Volume: 621 Page(s): E7 - E26
09/01/2023 Authors: COVID-19 Host Genetics Initiative
Exercise alleviates neovascular age-related macular degeneration by inhibiting AIM2 inflammasome in myeloid cells.
Metabolism Volume: 144 Page(s): 155584
07/01/2023 Authors: Cui B; Guo X; Zhou W; Zhang X; He K; Bai T; Lin D; Wei-Zhang S; Zhao Y; Liu S
Live-cell invasive phenotyping uncovers the ALK2/BMP6 iron homeostasis pathway as a therapeutic vulnerability in LKB1-mutant lung cancer.
bioRxiv
06/14/2023 Authors: Koo J; Seong C-S; Parker RE; Dwivedi B; Arthur RA; Dinasarapu AR; Johnston HR; Claussen H; Tucker-Burden C; Ramalingam SS
The role of innate and adaptive immunity in the sex bias of LKB1-mutant lung adenocarcinoma
Volume: 83
04/01/2023 Authors: Fan Y; Monterroza L; Jin R; Liu X; Selvaraj P; Tirouvanziam R; Zhou W
DeepFundus: A flow-cytometry-like image quality classifier for boosting the whole life cycle of medical artificial intelligence.
Cell Rep Med Volume: 4 Page(s): 100912
02/21/2023 Authors: Liu L; Wu X; Lin D; Zhao L; Li M; Yun D; Lin Z; Pang J; Li L; Wu Y
Loss of the endocytic tumor suppressor HD-PTP phenocopies LKB1 and promotes RAS-driven oncogenesis.
bioRxiv
01/27/2023 Authors: Seong C-S; Huang C; Boese AC; Hou Y; Koo J; Mouw JK; Rupji M; Joseph G; Johnston HR; Claussen H
Association of Physical Activity with Retinal Thickness and Vascular Structure in Elderly Chinese Population.
Ophthalmic Res Volume: 66 Page(s): 281 - 292
01/01/2023 Authors: Cui B; Zhu Y; Zhang X; He K; Shi Y; Yu J; Zhou W; Zhu Y; Yan H
Analysis of time-series gene expression data to explore mechanisms of isoniazid-induced liver toxicity.
Yi Chuan Volume: 44 Page(s): 501 - 509
06/20/2022 Authors: Tian Z-Z; Zhou C-X; Zhou W; Li M; Chu Y-P; Huai C; Qin S-Y
Lysozyme Protects Against Severe Acute Respiratory Syndrome Coronavirus 2 Infection and Inflammation in Human Corneal Epithelial Cells.
Invest Ophthalmol Vis Sci Volume: 63 Page(s): 16
06/01/2022 Authors: Song Y; Zhang H; Zhu Y; Zhao X; Lei Y; Zhou W; Yu J; Dong X; Wang X; Du M
Interruption of Klf5 acetylation in basal progenitor cells promotes luminal commitment by activating Notch signaling.
J Genet Genomics Volume: 49 Page(s): 579 - 582
06/01/2022 Authors: Zhang B; Xia S; Liu M; Li X; Shuai S; Tao W; Li Y; Ni JJ; Zhou W; Liao L
Systematic discovery of mutation-directed neo-protein-protein interactions in cancer.
Cell Volume: 185 Page(s): 1974 - 1985.e12
05/26/2022 Authors: Mo X; Niu Q; Ivanov AA; Tsang YH; Tang C; Shu C; Li Q; Qian K; Wahafu A; Doyle SP
A Feedback Regulatory Loop Containing McdR and WhiB2 Controls Cell Division and DNA Repair in Mycobacteria.
mBio Volume: 13 Page(s): e0334321
04/26/2022 Authors: Zhou W; Huang S; Cumming BM; Zhang Y; Tang W; Steyn AJC; Chen S; Hu Y
Integration of questionnaire-based risk factors improves polygenic risk scores for human coronary heart disease and type 2 diabetes.
Commun Biol Volume: 5 Page(s): 158
02/23/2022 Authors: Tamlander M; Mars N; Pirinen M; FinnGen; Widn E; Ripatti S
Association of cigarette smoking with retinal thickness and vascular structure in an elderly Chinese population.
Photodiagnosis Photodyn Ther Volume: 36 Page(s): 102481
12/01/2021 Authors: Cui B; He K; Zhang X; Zhou W; Sun Z; Zhang M; Shi Y; Lei Y; Yao L; Li Y
Structural basis for activation of Swi2/Snf2 ATPase RapA by RNA polymerase.
Nucleic Acids Res Volume: 49 Page(s): 10707 - 10716
10/11/2021 Authors: Shi W; Zhou W; Chen M; Yang Y; Hu Y; Liu B
Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun Volume: 12 Page(s): 2702
05/11/2021 Authors: Yang Y; Liu C; Zhou W; Shi W; Chen M; Zhang B; Schatz DG; Hu Y; Liu B
Characterization of the binding motif for the T3SS master regulator LcrF in Yersinia pseudotuberculosis.
FEMS Microbiol Lett Volume: 368
04/22/2021 Authors: Liu L; Huang S; Fei K; Zhou W; Chen S; Hu Y
Encapsulation of NIR-II AIEgens in Virus-like Particles for Bioimaging.
ACS Appl Mater Interfaces Volume: 13 Page(s): 17372 - 17379
04/21/2021 Authors: Min X; Zhang J; Li R-H; Xia F; Cheng S-Q; Li M; Zhu W; Zhou W; Li F; Sun Y
Genome-scale analyses of transcriptional start sites in Mycobacterium marinum under normoxic and hypoxic conditions.
BMC Genomics Volume: 22 Page(s): 235
04/06/2021 Authors: Huang S; Zhou W; Tang W; Zhang Y; Hu Y; Chen S
Corrigendum to "Re-expression of LKB1 in LKB1-mutant EKVX cells leads to resistance to paclitaxel through the up-regulation of MDR1 expression" [Lung Cancer 88/2 (2015) 131-138].
Lung Cancer Volume: 154 Page(s): 228
04/01/2021 Authors: Mao K; Liu F; Liu X; Khuri FR; Marcus AI; Li M; Zhou W
Corrigendum to "Inhibition of IGF1R enhances 2-deoxyglucose in the treatment of non-small cell lung cancer" [Lung Cancer 123 (2018) 36-43].
Lung Cancer Volume: 154 Page(s): 227
04/01/2021 Authors: Liu F; Liu Y; Liu X; Mao K; Zhong D; Marcus AI; Khuri FR; Sun S-Y; He Y; Zhou W
Acetylation of KLF5 maintains EMT and tumorigenicity to cause chemoresistant bone metastasis in prostate cancer.
Nat Commun Volume: 12 Page(s): 1714
03/17/2021 Authors: Zhang B; Li Y; Wu Q; Xie L; Barwick B; Fu C; Li X; Wu D; Xia S; Chen J
An expanded universe of cancer targets.
Cell Volume: 184 Page(s): 1142 - 1155
03/04/2021 Authors: Hahn WC; Bader JS; Braun TP; Califano A; Clemons PA; Druker BJ; Ewald AJ; Fu H; Jagu S; Kemp CJ
Prevalence and causes of bilateral visual impairment in rural areas of Tianjin, China - The Tianjin Eye Study.
Acta Ophthalmol Volume: 99 Page(s): e136 - e143
03/01/2021 Authors: Meng X; Zhou W; Sun Z; Han Q; Zhang J; Zhang H; Wang W; Zhong M; Wang M; Zhang J
Leflunomide Suppresses the Growth of LKB1-Inactivated Tumors in the Immune-Competent Host and Attenuates Distant Cancer Metastasis.
Mol Cancer Ther Volume: 20 Page(s): 274 - 283
02/01/2021 Authors: Jin R; Liu B; Liu X; Fan Y; Peng W; Huang C; Marcus A; Sica G; Gilbert-Ross M; Liu Y
Structural basis of bacterial 28 -mediated transcription reveals roles of the RNA polymerase zinc-binding domain.
EMBO J Volume: 39 Page(s): e104389
07/15/2020 Authors: Shi W; Zhou W; Zhang B; Huang S; Jiang Y; Schammel A; Hu Y; Liu B
Correction: Expression of death receptor 4 is positively regulated by MEK/ERK/AP-1 signaling and suppressed upon MEK inhibition.
J Biol Chem Volume: 295 Page(s): 8871
06/26/2020 Authors: Yao W; Oh Y-T; Deng J; Yue P; Deng L; Huang H; Zhou W; Sun S-Y
Correction: Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling.
J Biol Chem Volume: 295 Page(s): 8870
06/26/2020 Authors: Oh Y-T; Yue P; Zhou W; Balko JM; Black EP; Owonikoko TK; Khuri FR; Sun S-Y
Correction to: Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy.
Mol Cancer Volume: 19 Page(s): 93
05/20/2020 Authors: Xu K; Park D; Magis AT; Zhang J; Zhou W; Sica GL; Ramalingam SS; Curran WJ; Deng X
Subpopulation targeting of pyruvate dehydrogenase and GLUT1 decouples metabolic heterogeneity during collective cancer cell invasion.
Nat Commun Volume: 11 Page(s): 1533
03/24/2020 Authors: Commander R; Wei C; Sharma A; Mouw JK; Burton LJ; Summerbell E; Mahboubi D; Peterson RJ; Konen J; Zhou W
Leflunomide inhibits the growth of LKB1-inactivated tumors in both xenograft and immunocompetent genetically engineered mouse models
Volume: 79
07/01/2019 Authors: Jin R; Liu X; Peng W; Fan Y; Liu B; Yang S; Xing C-G; Gilbert-Ross M; Marcus A; Zhou W
Small Molecule KRAS Agonist for Mutant KRAS Cancer Therapy.
Mol Cancer Volume: 18 Page(s): 85
04/10/2019 Authors: Xu K; Park D; Magis AT; Zhang J; Zhou W; Sica GL; Ramalingam SS; Curran WJ; Deng X
Sox7 negatively regulates prostate-specific membrane antigen (PSMA) expression through PSMA-enhancer.
Prostate Volume: 79 Page(s): 370 - 378
03/01/2019 Authors: Peng W; Guo L; Tang R; Liu X; Jin R; Dong J-T; Xing C-G; Zhou W
Compositional complexity of rods and rings.
Mol Biol Cell Volume: 29 Page(s): 2303 - 2316
09/15/2018 Authors: Schiavon CR; Griffin ME; Pirozzi M; Parashuraman R; Zhou W; Jinnah HA; Reines D; Kahn RA
Inhibition of IGF1R enhances 2-deoxyglucose in the treatment of non-small cell lung cancer.
Lung Cancer Volume: 123 Page(s): 36 - 43
09/01/2018 Authors: Liu F; Liu Y; Liu X; Mao K; Zhong D; Marcus AI; Khuri FR; Sun S-Y; He Y; Zhou W
Phenformin enhances the therapeutic effect of selumetinib in KRAS-mutant non-small cell lung cancer irrespective of LKB1 status.
Oncotarget Volume: 8 Page(s): 59008 - 59022
08/29/2017 Authors: Zhang J; Nannapaneni S; Wang D; Liu F; Wang X; Jin R; Liu X; Rahman MA; Peng X; Qian G
Modulation of Bax and mTOR for cancer therapeutics
Volume: 77
07/01/2017 Authors: Li R; Ding C; Zhang J; Xie M; Park D; Ding Y; Chen G; Zhang G; Gilbert-Ross M; Zhou W
Modulation of Bax and mTOR for Cancer Therapeutics.
Cancer Res Volume: 77 Page(s): 3001 - 3012
06/01/2017 Authors: Li R; Ding C; Zhang J; Xie M; Park D; Ding Y; Chen G; Zhang G; Gilbert-Ross M; Zhou W
Image-guided genomics of phenotypically heterogeneous populations reveals vascular signalling during symbiotic collective cancer invasion.
Nat Commun Volume: 8 Page(s): 15078
05/12/2017 Authors: Konen J; Summerbell E; Dwivedi B; Galior K; Hou Y; Rusnak L; Chen A; Saltz J; Zhou W; Boise LH
Corrigendum: The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies.
Nat Commun Volume: 8 Page(s): 15350
04/18/2017 Authors: Li Z; Ivanov AA; Su R; Gonzalez-Pecchi V; Qi Q; Liu S; Webber P; McMillan E; Rusnak L; Pham C
Targeting adhesion signaling in KRAS, LKB1 mutant lung adenocarcinoma.
JCI Insight Volume: 2 Page(s): e90487
03/09/2017 Authors: Gilbert-Ross M; Konen J; Koo J; Shupe J; Robinson BS; Wiles WG; Huang C; Martin WD; Behera M; Smith GH
The OncoPPi network of cancer-focused protein-protein interactions to inform biological insights and therapeutic strategies.
Nat Commun Volume: 8 Page(s): 14356
02/16/2017 Authors: Li Z; Ivanov AA; Su R; Gonzalez-Pecchi V; Qi Q; Liu S; Webber P; McMillan E; Rusnak L; Pham C
TIF-IA: An oncogenic target of pre-ribosomal RNA synthesis.
Biochim Biophys Acta Volume: 1866 Page(s): 189 - 196
12/01/2016 Authors: Jin R; Zhou W
Expression of Death Receptor 4 Is Positively Regulated by MEK/ERK/AP-1 Signaling and Suppressed upon MEK Inhibition.
J Biol Chem Volume: 291 Page(s): 21694 - 21702
10/07/2016 Authors: Yao W; Oh Y-T; Deng J; Yue P; Deng L; Huang H; Zhou W; Sun S-Y
Developing a personalized anti-metastatic therapy to treat KRAS, LKB1-mutant lung adenocarcinoma
Volume: 76
07/01/2016 Authors: Gilbert-Ross M; Konen J; Koo J; Shupe J; Sica GL; Chen Z; Robinson BS; Behera M; Rossi MR; Smith GH
The regulation of pre-ribosomal RNA synthesis by LKB1
Volume: 76
07/01/2016 Authors: Jin R; Liu F; Liu X; Huang H; Wilkinson SC; Zhong D; Khuri FR; Fu H; Marcus AI; He Y
LKB1 kinase-dependent and -independent defects disrupt polarity and adhesion signaling to drive collagen remodeling during invasion.
Mol Biol Cell Volume: 27 Page(s): 1069 - 1084
04/01/2016 Authors: Konen J; Wilkinson S; Lee B; Fu H; Zhou W; Jiang Y; Marcus AI
An early treatment window to target FAK-dependent collective invasion in Lkb1-mutant lung adenocarcinoma
Volume: 76
04/01/2016 Authors: Gilbert-Ross M; Konen J; Shupe J; Koo J; Sica GL; Ramalingam SS; Fu H; Khuri FR; Zhou W; Marcus AI
LKB1 promotes cell survival by modulating TIF-IA-mediated pre-ribosomal RNA synthesis under uridine downregulated conditions.
Oncotarget Volume: 7 Page(s): 2519 - 2531
01/19/2016 Authors: Liu F; Jin R; Liu X; Huang H; Wilkinson SC; Zhong D; Khuri FR; Fu H; Marcus A; He Y
Fyn-phosphorylated PIKE-A binds and inhibits AMPK signaling, blocking its tumor suppressive activity.
Cell Death Differ Volume: 23 Page(s): 52 - 63
01/01/2016 Authors: Zhang S; Qi Q; Chan CB; Zhou W; Chen J; Luo HR; Appin C; Brat DJ; Ye K
2-Deoxyglucose Suppresses ERK Phosphorylation in LKB1 and Ras Wild-Type Non-Small Cell Lung Cancer Cells.
PLoS One Volume: 11 Page(s): e0168793
01/01/2016 Authors: Sun L; Liu X; Fu H; Zhou W; Zhong D
KLF5 inhibits angiogenesis in PTEN-deficient prostate cancer by attenuating AKT activation and subsequent HIF1 alpha accumulation
Volume: 75
08/01/2015 Authors: Ci X; Xing C; Zhang B; Zhang Z; Ni JJ; Zhou W; Dong J-T
Re-expression of LKB1 in LKB1-mutant EKVX cells leads to resistance to paclitaxel through the up-regulation of MDR1 expression.
Lung Cancer Volume: 88 Page(s): 131 - 138
05/01/2015 Authors: Mao K; Liu F; Liu X; Khuri FR; Marcus AI; Li M; Zhou W
KLF5 inhibits angiogenesis in PTEN-deficient prostate cancer by attenuating AKT activation and subsequent HIF1 accumulation.
Mol Cancer Volume: 14 Page(s): 91
04/21/2015 Authors: Ci X; Xing C; Zhang B; Zhang Z; Ni JJ; Zhou W; Dong J-T
RhoA, a novel tumor suppressor or oncogene as a therapeutic target?
Genes Dis Volume: 2 Page(s): 2 - 3
03/01/2015 Authors: Gilbert-Ross M; Marcus AI; Zhou W
Global transcriptome sequencing of ethnically diverse formalin-fixed patient samples identifies biomarkers of recurrence in prostate cancer
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION Volume: 23
11/01/2014 Authors: Xu J; Long Q; Osunkoya AO; Sannigrahi S; Johnson BA; Zhou W; Gillespie T; Park JY; Nam RK; Sugar L
Restoration of LKB1 defect in EKVX cells leads to resistance to microtubule targeting agents
Volume: 74
10/01/2014 Authors: Mao K; Liu F; Liu X; He Y; Khuri F; Marcus A; Li M; Zhou W
Global transcriptome analysis of formalin-fixed prostate cancer specimens identifies biomarkers of disease recurrence.
Cancer Res Volume: 74 Page(s): 3228 - 3237
06/15/2014 Authors: Long Q; Xu J; Osunkoya AO; Sannigrahi S; Johnson BA; Zhou W; Gillespie T; Park JY; Nam RK; Sugar L
Phenformin combines with selumetinib in targeting KRAS mutant non-small cell lung cancer cells with alternative LKB1 status.
Volume: 32
05/20/2014 Authors: Zhang J; Wang D; Qian G; Liu F; Rahman MA; Nannapaneni S; Wang X; Peng X; Chen ZG; Wong K-K
Biomarkers Differentially Expressed in Prostatic Adenocarcinoma Gleason Score 3+4=7 vs Gleason Score 4+3=7 Identified by Global Transcriptome Sequencing of Forman-Fixed Paraffin Embedded Tissue
Volume: 94 Page(s): 250A - 250A
02/01/2014 Authors: Moreno CS; Long Q; Xu J; Sannigrahi S; Johnson BA; Zhou W; Gillespie T; Park JY; Nam RK; Sugar L
Biomarkers Differentially Expressed in Prostatic Adenocarcinoma Gleason Score 3+4=7 vs Gleason Score 4+3=7 Identified by Global Transcriptome Sequencing of Formalin-Fixed Paraffin Embedded Tissue
Volume: 27 Page(s): 250A - 250A
02/01/2014 Authors: Moreno CS; Long Q; Xu J; Sannigrahi S; Johnson BA; Zhou W; Gillespie T; Park JY; Nam RK; Sugar L
Global Transcriptome Sequencing of Formalin Fixed Paraffin Embedded Patient Samples Identifies Biomarkers That Are Differentially Expressed between Caucasian and African American Men with Prostate Cancer
Volume: 27 Page(s): 250A - 250A
02/01/2014 Authors: Moreno CS; Xu J; Long Q; Sannigrahi S; Johnson BA; Zhou W; Gillespie T; Park JY; Nam RK; Sugar L
Global Transcriptome Sequencing of Formalin Fixed Paraffin Embedded Patient Samples Identifies Biomarkers That Are Differentially Expressed between Caucasian and African American Men with Prostate Cancer
Volume: 94 Page(s): 250A - 250A
02/01/2014 Authors: Moreno CS; Xu J; Long Q; Sannigrahi S; Johnson BA; Zhou W; Gillespie T; Park JY; Nam RK; Sugar L
Dysregulation of mTOR activity through LKB1 inactivation.
Chin J Cancer Volume: 32 Page(s): 427 - 433
08/01/2013 Authors: Zhou W; Marcus AI; Vertino PM
LKB1 represses focal adhesion kinase (FAK) signaling via a FAK-LKB1 complex to regulate FAK site maturation and directional persistence.
J Biol Chem Volume: 288 Page(s): 17663 - 17674
06/14/2013 Authors: Kline ER; Shupe J; Gilbert-Ross M; Zhou W; Marcus AI
RNAseq Analysis of FFPE Radical Prostatectomy Specimens Identifies Predictors of Biochemical Recurrence
Volume: 27
04/01/2013 Authors: Moreno CS; Long Q; Sannigrahi S; Xu J; Johnson BA; Zhou W; Nam RK; Seth A; Gillespie TW; Osunkoya AO
RNAseq Analysis of Formalin Fixed Paraffin Embedded Radical Prostatectomy Specimens Identifies Predictors of Biochemical Recurrence in Prostate Cancer
Volume: 26 Page(s): 235A - 235A
02/01/2013 Authors: Moreno CS; Long Q; Sannigrahi S; Xu J; Johnson BA; Zhou W; Seth AK; Nam RK; Petros JA; Gillespie TW
RNAseq Analysis of Formalin Fixed Paraffin Embedded Radical Prostatectomy Specimens Identifies Predictors of Biochemical Recurrence in Prostate Cancer
Volume: 93 Page(s): 235A - 235A
02/01/2013 Authors: Moreno CS; Long Q; Sannigrahi S; Xu J; Johnson BA; Zhou W; Seth AK; Nam RK; Petros JA; Gillespie TW
STE20-related kinase adaptor protein (STRAD) regulates cell polarity and invasion through PAK1 signaling in LKB1-null cells.
J Biol Chem Volume: 287 Page(s): 18758 - 18768
05/25/2012 Authors: Eggers CM; Kline ER; Zhong D; Zhou W; Marcus AI
Correlation of Immunohistochemical Expression of Protein-Coding Genes RAD23B, SIM2S, Notch3, BID and FBP with Biochemical Recurrence in Patients Following Radical Prostatectomy for Prostatic Adenocarcinoma
Volume: 92 Page(s): 230A - 230A
02/01/2012 Authors: Moreno CS; Sannigrahi S; Cheng J; Zhou W; Petros JA; Gillespie TW; Osunkoya AO
Correlation of Immunohistochemical Expression of Protein-Coding Genes RAD23B, SIM2S, Notch3, BID and FBP with Biochemical Recurrence in Patients Following Radical Prostatectomy for Prostatic Adenocarcinoma
Volume: 25 Page(s): 230A - 230A
02/01/2012 Authors: Moreno CS; Sannigrahi S; Cheng J; Zhou W; Petros JA; Gillespie TW; Osunkoya AO
Oncogenic Ras and B-Raf proteins positively regulate death receptor 5 expression through co-activation of ERK and JNK signaling.
J Biol Chem Volume: 287 Page(s): 257 - 267
01/02/2012 Authors: Oh Y-T; Yue P; Zhou W; Balko JM; Black EP; Owonikoko TK; Khuri FR; Sun S-Y
Protein-coding and microRNA biomarkers of recurrence of prostate cancer following radical prostatectomy.
Am J Pathol Volume: 179 Page(s): 46 - 54
07/01/2011 Authors: Long Q; Johnson BA; Osunkoya AO; Lai Y-H; Zhou W; Abramovitz M; Xia M; Bouzyk MB; Nam RK; Sugar L
LKB1 negatively regulates IGF-1 induced ERK phosphorylation
CANCER RESEARCH Volume: 71
04/15/2011 Authors: Zhong D; Liu X; Fu H; Sun S-Y; Khuri FR; Zhou W
RSK2 phosphorylates and activates CREB to promote HNSCC cell invasion through upregulation of pro-metastatic MCAM and Fascin-1
CANCER RESEARCH Volume: 71
04/15/2011 Authors: Jin L; Kim Y-M; Zhou W; Taunton J; Chen GZ; Shin DM; Khuri FR; Kang S
Protein-coding and MicroRNA Biomarkers of Recurrence of Prostate Cancer Following Radical Prostatectomy
FASEB JOURNAL Volume: 25
04/01/2011 Authors: Moreno CS; Long Q; Johnson BA; Osunkoya AO; Zhou W; Abramovitz M; Xia M; Bouzyk MB; Nam RK; Sugar L
LKB1 regulated pathways in lung cancer invasion and metastasis.
J Thorac Oncol Volume: 5 Page(s): 1883 - 1886
12/01/2010 Authors: Marcus AI; Zhou W
LKB1-dependent proteasomal degradation of STRAD alpha in non-small cell lung cancer
JOURNAL OF THORACIC ONCOLOGY Volume: 5 Page(s): S242 - S242
06/01/2010 Authors: Eggers CM; Zhou W; Marcus AI
p90 ribosomal S6 kinase 2 promotes invasion and metastasis of human head and neck squamous cell carcinoma cells.
J Clin Invest Volume: 120 Page(s): 1165 - 1177
04/01/2010 Authors: Kang S; Elf S; Lythgoe K; Hitosugi T; Taunton J; Zhou W; Xiong L; Wang D; Muller S; Fan S
Homozygous deletion of the STK11/LKB1 locus and the generation of novel fusion transcripts in cervical cancer cells.
Cancer Genet Cytogenet Volume: 197 Page(s): 130 - 141
03/01/2010 Authors: McCabe MT; Powell DR; Zhou W; Vertino PM
The glycolytic inhibitor 2-deoxyglucose activates multiple prosurvival pathways through IGF1R.
J Biol Chem Volume: 284 Page(s): 23225 - 23233
08/28/2009 Authors: Zhong D; Xiong L; Liu T; Liu X; Liu X; Chen J; Sun S-Y; Khuri FR; Zong Y; Zhou Q
Implication of snoRNA U50 in human breast cancer.
J Genet Genomics Volume: 36 Page(s): 447 - 454
08/01/2009 Authors: Dong X-Y; Guo P; Boyd J; Sun X; Li Q; Zhou W; Dong J-T
LKB1 is required for adiponectin-mediated modulation of AMPK-S6K axis and inhibition of migration and invasion of breast cancer cells.
Oncogene Volume: 28 Page(s): 2621 - 2633
07/23/2009 Authors: Taliaferro-Smith L; Nagalingam A; Zhong D; Zhou W; Saxena NK; Sharma D
Germline mutation of microRNA-125a is associated with breast cancer.
J Med Genet Volume: 46 Page(s): 358 - 360
05/01/2009 Authors: Li W; Duan R; Kooy F; Sherman SL; Zhou W; Jin P
Phospho-proteomic analysis reveals the activation of ERK signaling by 2-deoxyglucose in NSCLC
CANCER RESEARCH Volume: 69
05/01/2009 Authors: Zhong D; Xiong L; Liu T; Liu X; Chen J; Zhou W
Adiponectin-mediated inhibition of metastatic properties of breast cancer cells involves upregulation of tumor suppressor gene, LKB1 and modulation of AMPK-S6K axis.
CANCER RESEARCH Volume: 69
05/01/2009 Authors: Taliaferro-Smith L; Nagalingam A; Zhong D; Zhou W; Knight B; Oberlick E; Saxena N; Sharma D
Reduced Rap1 Signaling Is Associated with Prostate Cancer Progression, Migration, Invasion, and Metastasis
FASEB JOURNAL Volume: 23
04/01/2009 Authors: Henderson VM; Osunkoya A; Zhou W; Williams D; Anderson N; Kitayama H; Csete M; Moreno CS
Protein-coding and MicroRNA Biomarker Gene Panels Predictive of Clinical Recurrence in Prostate Cancer
FASEB JOURNAL Volume: 23
04/01/2009 Authors: Moreno CS; Lai Y-H; Seth A; Osunkoya AO; Zhou W; Petros JA; Johnson BA; Nam RK; Barwick BG; Abramovitz M
Reduced Rap1 Signaling Is Associated with Prostate Cancer Progression, Migration, Invasion, and Metastasis
FASEB JOURNAL Volume: 23
04/01/2009 Authors: Henderson VM; Osunkoya A; Zhou W; Williams D; Anderson N; Kitayama H; Csete M; Moreno CS
PROTEIN-CODING AND MICRORNA BIOMARKER GENE PANELS PREDICTIVE OF CLINICAL RECURRENCE IN PROSTATE CANCER
Volume: 181 Page(s): 776 - 776
04/01/2009 Authors: Petros JA; Lai Y-H; Toronto AS; Osunkoya AO; Zhou W; Johnson BA; Toronto RN; Barwick B; Abramovitz M; Bouzyk M
Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor.
Mol Biol Cell Volume: 20 Page(s): 757 - 768
02/01/2009 Authors: Liu Z; Oh S-M; Okada M; Liu X; Cheng D; Peng J; Brat DJ; Sun S-Y; Zhou W; Gu W
RAP1 Signaling in Prostate Cancer Progression
Volume: 89 Page(s): 185A - 185A
01/01/2009 Authors: Moreno CS; Henderson VM; Zhou W; Williams D; Laycock N; Kitayama H; Osunkoya AO
RAP1 Signaling in Prostate Cancer Progression
Volume: 22 Page(s): 185A - 185A
01/01/2009 Authors: Moreno CS; Henderson VM; Zhou W; Williams D; Laycock N; Kitayama H; Osunkoya AO
LKB1 is necessary for Akt-mediated phosphorylation of proapoptotic proteins.
Cancer Res Volume: 68 Page(s): 7270 - 7277
09/15/2008 Authors: Zhong D; Liu X; Khuri FR; Sun S-Y; Vertino PM; Zhou W
Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells.
Mol Cancer Res Volume: 6 Page(s): 1421 - 1430
09/01/2008 Authors: Guo L; Zhong D; Lau S; Liu X; Dong X-Y; Sun X; Yang VW; Vertino PM; Moreno CS; Varma V
EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1.
Cell Cycle Volume: 7 Page(s): 2409 - 2417
08/01/2008 Authors: Thomas SL; Zhong D; Zhou W; Malik S; Liotta D; Snyder JP; Hamel E; Giannakakou P
2-Deoxyglucose induces Akt phosphorylation via a mechanism independent of LKB1/AMP-activated protein kinase signaling activation or glycolysis inhibition.
Mol Cancer Ther Volume: 7 Page(s): 809 - 817
04/01/2008 Authors: Zhong D; Liu X; Schafer-Hales K; Marcus AI; Khuri FR; Sun S-Y; Zhou W
SnoRNA U50 is a candidate tumor-suppressor gene at 6q14.3 with a mutation associated with clinically significant prostate cancer.
Hum Mol Genet Volume: 17 Page(s): 1031 - 1042
04/01/2008 Authors: Dong X-Y; Rodriguez C; Guo P; Sun X; Talbot JT; Zhou W; Petros J; Li Q; Vessella RL; Kibel AS
Counting alleles in single lesions of prostate tumors from ethnically diverse patients.
Prostate Volume: 68 Page(s): 231 - 240
02/15/2008 Authors: Morikawa A; Varma V; Gillespie TW; Lyles RH; Goodman M; Bostick RM; Mandel JS; Zhou W
The tumor suppressor LKB1 regulates lung cancer cell polarity by mediating cdc42 recruitment and activity.
Cancer Res Volume: 68 Page(s): 740 - 748
02/01/2008 Authors: Zhang S; Schafer-Hales K; Khuri FR; Zhou W; Vertino PM; Marcus AI
Frequent inactivation of RAMP2, EFEMP1 and Dutt1 in lung cancer by promoter hypermethylation.
Clin Cancer Res Volume: 13 Page(s): 4336 - 4344
08/01/2007 Authors: Yue W; Dacic S; Sun Q; Landreneau R; Guo M; Zhou W; Siegfried JM; Yu J; Zhang L
The amplified WWP1 gene is a potential molecular target in breast cancer.
Int J Cancer Volume: 121 Page(s): 80 - 87
07/01/2007 Authors: Chen C; Zhou Z; Ross JS; Zhou W; Dong J-T
Ubiquitin E3 ligase WWP1 as an oncogenic factor in human prostate cancer.
Oncogene Volume: 26 Page(s): 2386 - 2394
04/05/2007 Authors: Chen C; Sun X; Guo P; Dong X-Y; Sethi P; Zhou W; Zhou Z; Petros J; Frierson HF; Vessella RL
Infrequent mutation of ATBF1 in human breast cancer.
J Cancer Res Clin Oncol Volume: 133 Page(s): 103 - 105
02/01/2007 Authors: Sun X; Zhou Y; Otto KB; Wang M; Chen C; Zhou W; Subramanian K; Vertino PM; Dong J-T
Getting more from digital SNP data.
Stat Med Volume: 25 Page(s): 3124 - 3133
09/30/2006 Authors: El Karoui N; Zhou W; Whittemore AS
LKB1 mutation in large cell carcinoma of the lung.
Lung Cancer Volume: 53 Page(s): 285 - 294
09/01/2006 Authors: Zhong D; Guo L; de Aguirre I; Liu X; Lamb N; Sun S-Y; Gal AA; Vertino PM; Zhou W
FOXO1A is a candidate for the 13q14 tumor suppressor gene inhibiting androgen receptor signaling in prostate cancer.
Cancer Res Volume: 66 Page(s): 6998 - 7006
07/15/2006 Authors: Dong X-Y; Chen C; Sun X; Guo P; Vessella RL; Wang R-X; Chung LWK; Zhou W; Dong J-T
Homozygous deletion of SMAD4 in breast cancer cell lines and invasive ductal carcinomas.
Cancer Biol Ther Volume: 5 Page(s): 601 - 607
06/01/2006 Authors: Zhong D; Morikawa A; Guo L; Colpaert C; Xiong L; Nassar A; Chen C; Lamb N; Dong J-T; Zhou W
Anti-HIF Activity of curcumin and analog EF24.
Volume: 66
04/01/2006 Authors: Thomas SL; O'Brate AM; Malik S; Zhong D; Zhou W; Snyder JP; Liotta D; Giannakakou P
Homozygous deletion of LKB1 mutation in H157 lung cancer cell line
Volume: 66
04/01/2006 Authors: Zhong D; Guo L; de Aguirre I; Liu X; Lamb N; Sun S; Gal A; Vertino PM; Zhou W
Significance of chromosome 8p allele status in prostate cancer progression among radical prostatectomy patients at Atlanta VA Medical Center.
Volume: 66
04/01/2006 Authors: Morikawa A; Varma V; Gillespie T; Lyles R; Bostick R; Goodman M; Mandel J; Zhou W
WWP1 E3 ubiquitin ligase is a potential oncogene in human prostate and breast cancer
Volume: 66
04/01/2006 Authors: Chen C; Zhou W; Petros J; Frierson HF; Vessella RL; Li Q; Simons JW; Dong J-T
Chromosomal deletions as predictors for recurrence of early stage colorectal cancer
Volume: 149 Page(s): 156 - 161
01/01/2006 Authors: Zhou W
Resistance to microtubule-stabilizing drugs involves two events: beta-tubulin mutation in one allele followed by loss of the second allele.
Cell Cycle Volume: 4 Page(s): 1847 - 1853
12/01/2005 Authors: Wang Y; O'Brate A; Zhou W; Giannakakou P
LKB1/AMPK/TSC2 signaling pathway alterations in non-small cell lung cancer
Volume: 49 Page(s): S69 - S69
07/01/2005 Authors: De Aguirre I; Zhong D; Zhou W; Rosell R; Vertino P
Identification of a novel small-molecule inhibitor of the hypoxia-inducible factor 1 pathway.
Cancer Res Volume: 65 Page(s): 605 - 612
01/15/2005 Authors: Tan C; de Noronha RG; Roecker AJ; Pyrzynska B; Khwaja F; Zhang Z; Zhang H; Teng Q; Nicholson AC; Giannakakou P
Allelic imbalances of chromosomes 8p and 18q and their roles in distant relapse of early stage, node-negative breast cancer.
Breast Cancer Res Volume: 7 Page(s): R1051 - R1057
01/01/2005 Authors: Morikawa A; Williams TY; Dirix L; Colpaert C; Goodman M; Lyles RH; Zhong D; Zhou W
Surgical margin and Gleason score as predictors of postoperative recurrence in prostate cancer with or without chromosome 8p allelic imbalance.
Prostate Volume: 61 Page(s): 81 - 91
09/15/2004 Authors: Zhou W; Goodman M; Lyles RH; Lim SD; Williams TY; Rusthoven KE; Mandel JS; Amin MB; Petros JA
Allelic variations in gene expression.
Curr Opin Oncol Volume: 16 Page(s): 39 - 43
01/01/2004 Authors: Yan H; Zhou W
Allelic imbalances of chromosome 8p and 18q and their roles in distant relapse of early stage, node-negative breast cancer.
Volume: 88 Page(s): S196 - S196
01/01/2004 Authors: Morikawa A; Williams T; Colpaert C; Goodman M; Lyles RH; Zhong D; Zhou W
Alterations in molecular pathways of diffusely infiltrating glial neoplasms: application to tumor classification and anti-tumor therapy (Review).
Int J Oncol Volume: 23 Page(s): 857 - 869
10/01/2003 Authors: Hunter SB; Brat DJ; Olson JJ; Von Deimling A; Zhou W; Van Meir EG
Analysis of allelic imbalance (AI) on chromosome (chr) 8p and 18 in prostate cancer (PCa) by a novel technique: "Counting alleles" to estimate loss of heterozygosity (LOH)
Volume: 83 Page(s): 159A - 159A
01/01/2003 Authors: Lim SD; Zhou W; Williams TY; Rusthoven KE; Lyles R; Benjamin M; Petros JA; Amin MB
Analysis of allelic imbalance (AI) on chromosome (chr) 8p and 18 in prostate cancer (PCa) by a novel technique: "Counting alleles" to estimate loss of heterozygosity (LOH)
Volume: 16 Page(s): 159A - 159A
01/01/2003 Authors: Lim SD; Zhou W; Williams TY; Rusthoven KE; Lyles R; Benjamin M; Petros JA; Amin MB
Mapping genetic alterations in tumors with single nucleotide polymorphisms.
Curr Opin Oncol Volume: 15 Page(s): 50 - 54
01/01/2003 Authors: Zhou W
Counting alleles to predict recurrence of early-stage colorectal cancers.
Lancet Volume: 359 Page(s): 219 - 225
01/19/2002 Authors: Zhou W; Goodman SN; Galizia G; Lieto E; Ferraraccio F; Pignatelli C; Purdie CA; Piris J; Morris R; Harrison DJ
Evidence that genetic instability occurs at an early stage of colorectal tumorigenesis.
Cancer Res Volume: 61 Page(s): 818 - 822
02/01/2001 Authors: Shih IM; Zhou W; Goodman SN; Lengauer C; Kinzler KW; Vogelstein B
Counting alleles reveals a connection between chromosome 18q loss and vascular invasion.
Nat Biotechnol Volume: 19 Page(s): 78 - 81
01/01/2001 Authors: Zhou W; Galizia G; Lieto E; Goodman SN; Romans KE; Kinzler KW; Vogelstein B; Choti MA; Montgomery EA
Analysis of human transcriptomes.
Nat Genet Volume: 23 Page(s): 387 - 388
12/01/1999 Authors: Velculescu VE; Madden SL; Zhang L; Lash AE; Yu J; Rago C; Lal A; Wang CJ; Beaudry GA; Ciriello KM
Identifying markers for pancreatic cancer by gene expression analysis.
Cancer Epidemiol Biomarkers Prev Volume: 7 Page(s): 109 - 112
02/01/1998 Authors: Zhou W; Sokoll LJ; Bruzek DJ; Zhang L; Velculescu VE; Goldin SB; Hruban RH; Kern SE; Hamilton SR; Chan DW
Serial analysis of gene expression (SAGE).
AMERICAN JOURNAL OF HUMAN GENETICS Volume: 61 Page(s): A36 - A36
10/01/1997 Authors: Velculescu VE; Zhang L; Zhou W; Polyak K; Basrai M; Bassett D; Hieter P; Vogelstein B; Kinzler KW
Gene expression: a looking glass for cancer
AMERICAN JOURNAL OF HUMAN GENETICS Volume: 61 Page(s): A89 - A89
10/01/1997 Authors: Zhang L; Zhou W; Velculescu VE; Kern SE; Hruban RH; Hamilton SR; Vogelstein B; Kinzler KW
Gene expression profiles in normal and cancer cells.
Science Volume: 276 Page(s): 1268 - 1272
05/23/1997 Authors: Zhang L; Zhou W; Velculescu VE; Kern SE; Hruban RH; Hamilton SR; Vogelstein B; Kinzler KW
Characterization of the yeast transcriptome.
Cell Volume: 88 Page(s): 243 - 251
01/24/1997 Authors: Velculescu VE; Zhang L; Zhou W; Vogelstein J; Basrai MA; Bassett DE; Hieter P; Vogelstein B; Kinzler KW
RNA polymerase bypass at sites of dihydrouracil: implications for transcriptional mutagenesis.
Mol Cell Biol Volume: 15 Page(s): 6729 - 6735
12/01/1995 Authors: Liu J; Zhou W; Doetsch PW
T7 RNA polymerase bypass of large gaps on the template strand reveals a critical role of the nontemplate strand in elongation.
Cell Volume: 82 Page(s): 577 - 585
08/25/1995 Authors: Zhou W; Reines D; Doetsch PW
Transcription bypass or blockage at single-strand breaks on the DNA template strand: effect of different 3' and 5' flanking groups on the T7 RNA polymerase elongation complex.
Biochemistry Volume: 33 Page(s): 14926 - 14934
12/13/1994 Authors: Zhou W; Doetsch PW
Efficient bypass and base misinsertions at abasic sites by prokaryotic RNA polymerases.
Ann N Y Acad Sci Volume: 726 Page(s): 351 - 354
07/29/1994 Authors: Zhou W; Doetsch PW
Effects of abasic sites and DNA single-strand breaks on prokaryotic RNA polymerases.
Proc Natl Acad Sci U S A Volume: 90 Page(s): 6601 - 6605
07/15/1993 Authors: Zhou W; Doetsch PW
Efficacy of the immunoblot assay for cysticercosis in pigs and modulated expression of distinct IgM/IgG activities to Taenia solium antigens in experimental infections.
Vet Immunol Immunopathol Volume: 29 Page(s): 69 - 78
08/01/1991 Authors: Tsang VC; Pilcher JA; Zhou W; Boyer AE; Kamango-Sollo EI; Rhoads ML; Murrell KD; Schantz PM; Gilman RH
Guatemalan human onchocerciasis. I. Systematic analysis of patient populations, nodular antigens, and specific isotypic reactions.
J Immunol Volume: 146 Page(s): 3993 - 4000
06/01/1991 Authors: Tsang VC; Boyer AE; Pilcher JB; Eberhard ML; Reimer CB; Zea-Flores G; Zea-Flores R; Zhou W; Richards FO
Guatemalan human onchocerciasis. II. Evidence for IgG3 involvement in acquired immunity to Onchocerca volvulus and identification of possible immune-associated antigens.
J Immunol Volume: 146 Page(s): 4001 - 4010
06/01/1991 Authors: Boyer AE; Tsang VC; Eberhard ML; Zea-Flores G; Hightower A; Pilcher JB; Zea-Flores R; Zhou W; Reimer CB
Optimization of binding capacity and specificity of protein G on various solid matrices for immunoglobulins.
J Immunol Methods Volume: 136 Page(s): 279 - 286
02/15/1991 Authors: Pilcher JB; Tsang VC; Zhou W; Black CM; Sidman C
Bleomycin A2 and B2 purification by flash chromatography for chemical and biochemical studies.
Prep Biochem Volume: 21 Page(s): 257 - 268
01/01/1991 Authors: Freyder CP; Zhou W; Doetsch PW; Marzilli LG
Comparison of particulate 3,3',5,5'-tetramethylbenzidine and 3,3'-diaminobenzidine as chromogenic substrates for immunoblot.
Biotechniques Volume: 8 Page(s): 58 - 60
01/01/1990 Authors: Brand JA; Tsang VC; Zhou W; Shukla SB

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