Weibo Niu
- Department of Psychiatry and Behavioral Sciences
Instructor
- (678) 296-5538
- weibo.niu@emory.edu
- Website
Overview
My primary research interest lies in elucidating the biological functions of risk genes associated with mental disorders during neural development and their contributions to the pathogenesis of neuropsychiatric and neurodevelopmental disorders. I am employing patient-derived induced pluripotent stem cells (iPSCs) to investigate the molecular mechanisms underlying neuropsychiatric and neurodevelopmental disorders, with the goal of translating this knowledge into therapeutic targets for developing novel treatments.
Academic Appointment
- Instructor, Psychiatry and Behavioral Sciences, Emory University
Education
Degrees
- PhD from Shanghai Jiao Tong University
Research
Publications
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Non-Invasive Quality Control of Organoid Cultures Using Mesofluidic CSTR Bioreactors and High-Content Imaging.
Adv Mater Technol Volume: 10
02/05/2025 Authors: Charles S; Jackson-Holmes E; Sun G; Zhou Y; Siciliano B; Niu W; Han H; Nikitina A; Kemp ML; Wen Z -
Longitudinal multi-omics reveals pathogenic TSC2 variants disrupt developmental trajectories of human cortical organoids derived from Tuberous Sclerosis Complex.
bioRxiv
10/11/2024 Authors: Niu W; Yu S; Li X; Wang Z; Chen R; Michalski C; Jahangiri A; Zohdy Y; Chern JJ; Whitworth TJ -
Non-invasive label-free imaging analysis pipeline for in situ characterization of 3D brain organoids.
Sci Rep Volume: 14 Page(s): 22331
09/27/2024 Authors: Serafini CE; Charles S; Casteleiro Costa P; Niu W; Cheng B; Wen Z; Lu H; Robles FE -
Non-Invasive Quality Control of Organoid Cultures Using Mesofluidic CSTR Bioreactors and High-Content Imaging.
bioRxiv
07/23/2024 Authors: Charles S; Jackson-Holmes E; Sun G; Zhou Y; Siciliano B; Niu W; Han H; Nikitina A; Kemp ML; Wen Z -
Non-Invasive Label-free Analysis Pipeline for In Situ Characterization of Differentiation in 3D Brain Organoid Models.
Res Sq
04/01/2024 Authors: Filan C; Charles S; Casteleiro Costa P; Niu W; Cheng BF; Wen Z; Lu H; Robles FE -
Modeling tuberous sclerosis complex with human induced pluripotent stem cells.
World J Pediatr Volume: 20 Page(s): 208 - 218
03/01/2024 Authors: Niu W; Siciliano B; Wen Z -
Electrophysiological and morphological characterization of single neurons in intact human brain organoids.
J Neurosci Methods Volume: 394 Page(s): 109898
07/01/2023 Authors: Landry CR; Yip MC; Zhou Y; Niu W; Wang Y; Yang B; Wen Z; Forest CR -
The association between rs1260326 with the risk of NAFLD and the mediation effect of triglyceride on NAFLD in the elderly Chinese Han population.
Aging (Albany NY) Volume: 14 Page(s): 2736 - 2747
03/25/2022 Authors: Yuan F; Gu Z; Bi Y; Yuan R; Niu W; Ren D; Zhang L; He G; Liu B-C -
Upregulation of DGCR8, a Candidate Predisposing to Schizophrenia in Han Chinese, Contributes to Phenotypic Deficits and Neuronal Migration Delay.
Front Psychiatry Volume: 13 Page(s): 873873
01/01/2022 Authors: Bi Y; Chen S; Shen Q; Guo Z; Ren D; Yuan F; Niu W; Ji L; Liu L; Han K -
A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies.
Nat Neurosci Volume: 24 Page(s): 1377 - 1391
10/01/2021 Authors: Kang Y; Zhou Y; Li Y; Han Y; Xu J; Niu W; Li Z; Liu S; Feng H; Huang W