Publications

• Immune microenvironment remodeling after radiation of a progressing brain metastasis.
  Cell Rep Med Volume: 4 Page(s): 101054
  06/20/2023 Authors: Hudson WH; Olson JJ; Sudmeier LJ
• mTOR regulates T cell exhaustion and PD-1-targeted immunotherapy response during chronic viral infection.
  J Clin Invest Volume: 133
  01/17/2023 Authors: Ando S; Perkins CM; Sajiki Y; Chastain C; Valanparambil RM; Wieland A; Hudson WH; Hashimoto M; Ramalingam SS; Freeman GJ
• TGF- regulates the stem-like state of PD-1+ TCF-1+ virus-specific CD8 T cells during chronic infection.
  J Exp Med Volume: 219
  10/03/2022 Authors: Hu Y; Hudson WH; Kissick HT; Medina CB; Baptista AP; Ma C; Liao W; Germain RN; Turley SJ; Zhang N
• PD-1 combination therapy with IL-2 modifies CD8+ T cell exhaustion program.
  Nature Volume: 610 Page(s): 173 - 181
  10/01/2022 Authors: Hashimoto M; Araki K; Cardenas MA; Li P; Jadhav RR; Kissick HT; Hudson WH; McGuire DJ; Obeng RC; Wieland A
• Deep mutational scanning identifies SARS-CoV-2 Nucleocapsid escape mutations of currently available rapid antigen tests.
  Cell Volume: 185 Page(s): 3603 - 3616.e13
  09/15/2022 Authors: Frank F; Keen MM; Rao A; Bassit L; Liu X; Bowers HB; Patel AB; Cato ML; Sullivan JA; Greenleaf M
• Localization of Tcell clonotypes using the Visium spatial transcriptomics platform.
  STAR Protoc Volume: 3 Page(s): 101391
  06/17/2022 Authors: Hudson WH; Sudmeier LJ
• Distinct phenotypic states and spatial distribution of CD8+ Tcell clonotypes in human brain metastases.
  Cell Rep Med Volume: 3 Page(s): 100620
  05/17/2022 Authors: Sudmeier LJ; Hoang KB; Nduom EK; Wieland A; Neill SG; Schniederjan MJ; Ramalingam SS; Olson JJ; Ahmed R; Hudson WH
• Supporting the Next Generation of Scientists to Lead Cancer Immunology Research.
  Cancer Immunol Res Volume: 9 Page(s): 1245 - 1251
  11/01/2021 Authors: Alspach E; Chow RD; Demehri S; Guerriero JL; Gujar S; Hartmann FJ; Helmink BA; Hudson WH; Ho WJ; Ma L
• Defining HPV-specific B cell responses in patients with head and neck cancer.
  Nature Volume: 597 Page(s): 274 - 278
  09/01/2021 Authors: Wieland A; Patel MR; Cardenas MA; Eberhardt CS; Hudson WH; Obeng RC; Griffith CC; Wang X; Chen ZG; Kissick HT
• Infection- and vaccine-induced antibody binding and neutralization of the B.1.351 SARS-CoV-2 variant.
  Cell Host Microbe Volume: 29 Page(s): 516 - 521.e3
  04/14/2021 Authors: Edara VV; Norwood C; Floyd K; Lai L; Davis-Gardner ME; Hudson WH; Mantus G; Nyhoff LE; Adelman MW; Fineman R
• Rapid Generation of Neutralizing Antibody Responses in COVID-19 Patients.
  Cell Rep Med Volume: 1 Page(s): 100040
  06/23/2020 Authors: Suthar MS; Zimmerman MG; Kauffman RC; Mantus G; Linderman SL; Hudson WH; Vanderheiden A; Nyhoff L; Davis CW; Adekunle O
• PD-1+ stemlike CD8 T cells are resident in lymphoid tissues during persistent LCMV infection.
  Proc Natl Acad Sci U S A Volume: 117 Page(s): 4292 - 4299
  02/25/2020 Authors: Im SJ; Konieczny BT; Hudson WH; Masopust D; Ahmed R
• Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection.
  Immunity Volume: 51 Page(s): 1043 - 1058.e4
  12/17/2019 Authors: Hudson WH; Gensheimer J; Hashimoto M; Wieland A; Valanparambil RM; Li P; Lin J-X; Konieczny BT; Im SJ; Freeman GJ
• An intra-tumoral niche maintains and differentiates stem-like CD8 T cells.
  Nature Volume: 576 Page(s): 465 - 470
  12/01/2019 Authors: Jansen CS; Prokhnevska N; Master VA; Sanda MG; Carlisle JW; Bilen MA; Cardenas M; Wilkinson S; Lake R; Sowalsky AG
• The Magnitude of IFN- Responses Is Fine-Tuned by DNA Architecture and the Non-coding Transcript of Ifng-as1.
  Mol Cell Volume: 75 Page(s): 1229 - 1242.e5
  09/19/2019 Authors: Petermann F; Pkowska A; Johnson CA; Jankovic D; Shih H-Y; Jiang K; Hudson WH; Brooks SR; Sun H-W; Villarino AV
• Expression of novel long noncoding RNAs defines virus-specific effector and memory CD8+ T cells.
  Nat Commun Volume: 10 Page(s): 196
  01/14/2019 Authors: Hudson WH; Prokhnevska N; Gensheimer J; Akondy R; McGuire DJ; Ahmed R; Kissick HT
• Distinct Gene Expression Profiles Define Anaplastic Grade in Retinoblastoma.
  Am J Pathol Volume: 188 Page(s): 2328 - 2338
  10/01/2018 Authors: Hudson LE; Mendoza P; Hudson WH; Ziesel A; Hubbard GB; Wells J; Dwivedi B; Kowalski J; Seby S; Patel V
• Cryptic glucocorticoid receptor-binding sites pervade genomic NF-B response elements.
  Nat Commun Volume: 9 Page(s): 1337
  04/06/2018 Authors: Hudson WH; Vera IMSD; Nwachukwu JC; Weikum ER; Herbst AG; Yang Q; Bain DL; Nettles KW; Kojetin DJ; Ortlund EA
• Tethering not required: the glucocorticoid receptor binds directly to activator protein-1 recognition motifs to repress inflammatory genes.
  Nucleic Acids Res Volume: 45 Page(s): 8596 - 8608
  08/21/2017 Authors: Weikum ER; de Vera IMS; Nwachukwu JC; Hudson WH; Nettles KW; Kojetin DJ; Ortlund EA
• Human antibody responses after dengue virus infection are highly cross-reactive to Zika virus.
  Proc Natl Acad Sci U S A Volume: 113 Page(s): 7852 - 7857
  07/12/2016 Authors: Priyamvada L; Quicke KM; Hudson WH; Onlamoon N; Sewatanon J; Edupuganti S; Pattanapanyasat K; Chokephaibulkit K; Mulligan MJ; Wilson PC
• Distal substitutions drive divergent DNA specificity among paralogous transcription factors through subdivision of conformational space.
  Proc Natl Acad Sci U S A Volume: 113 Page(s): 326 - 331
  01/12/2016 Authors: Hudson WH; Kossmann BR; de Vera IMS; Chuo S-W; Weikum ER; Eick GN; Thornton JW; Ivanov IN; Kojetin DJ; Ortlund EA
• The structure, function and evolution of proteins that bind DNA and RNA.
  Nat Rev Mol Cell Biol Volume: 15 Page(s): 749 - 760
  11/01/2014 Authors: Hudson WH; Ortlund EA
• The structural basis of direct glucocorticoid-mediated transrepression.
  Nat Struct Mol Biol Volume: 20 Page(s): 53 - 58
  01/01/2013 Authors: Hudson WH; Youn C; Ortlund EA
• Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation.
  Nat Struct Mol Biol Volume: 19 Page(s): 532 - 5S2
  04/15/2012 Authors: Musille PM; Pathak M; Lauer JL; Hudson WH; Griffin PR; Ortlund EA