Publications

• The association of azole antifungals with overall survival in patients with non-small cell lung cancer receiving immune checkpoint inhibitors.
  Oncologist Volume: 30
  02/06/2025 Authors: Sebastian NT; Stokes WA; Behera M; Jiang R; Gutman DA; Huang Z; Burns A; Sukhatme V; Lowe MC; Ramalingam SS
• Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine.
  Cell Rep Med Volume: 6 Page(s): 101881
  01/21/2025 Authors: Nagaraju GP; Saddala MS; Foote JB; Khaliq AM; Masood A; Golivi Y; Bandi DSR; Sarvesh S; Reddy SP; Switchenko J
• Why Certain Repurposed Drugs Are Unlikely to Be Effective Antivirals to Treat SARS-CoV-2 Infections.
  Viruses Volume: 16
  04/22/2024 Authors: Hurwitz SJ; De R; LeCher JC; Downs-Bowen JA; Goh SL; Zandi K; McBrayer T; Amblard F; Patel D; Kohler JJ
• Addendum: Resolvins suppress tumor growth and enhance cancer therapy.
  J Exp Med Volume: 221
  03/04/2024 Authors: Sulciner ML; Serhan CN; Gilligan MM; Mudge DK; Chang J; Gartung A; Lehner KA; Bielenberg DR; Schmidt B; Dalli J
• Engaging Cancer Care Physicians in Off-Label Drug Clinical Trials: Human-Centered Design Approach.
  JMIR Form Res Volume: 8 Page(s): e51604
  02/15/2024 Authors: Parsell MC; Greenleaf MN; Kombara GG; Sukhatme VP; Lam WA
• Taxane chemotherapy induces stromal injury that leads to breast cancer dormancy escape.
  PLoS Biol Volume: 21 Page(s): e3002275
  09/01/2023 Authors: Ganesan R; Bhasin SS; Bakhtiary M; Krishnan U; Cheemarla NR; Thomas BE; Bhasin MK; Sukhatme VP
• The Association of Improved Overall Survival with NSAIDs in Non-Small Cell Lung Cancer Patients Receiving Immune Checkpoint Inhibitors.
  Clin Lung Cancer Volume: 24 Page(s): 287 - 294
  05/01/2023 Authors: Sebastian NT; Stokes WA; Behera M; Jiang R; Gutman DA; Huang Z; Burns A; Sukhatme V; Lowe MC; Ramalingam SS
• Readily available drugs and other interventions to potentially improve the efficacy of immune checkpoint blockade in cancer.
  Front Immunol Volume: 14 Page(s): 1281744
  01/01/2023 Authors: Coleman M; Mascialino SJ; Panjwani A; Edwards E; Sukhatme VV; Gavegnano C; Sukhatme VP
• Impact of concomitant fibrates on immunotherapy outcomes for advanced non-small cell lung cancer.
  Cancer Med Volume: 12 Page(s): 358 - 367
  01/01/2023 Authors: Stokes WA; Behera M; Jiang R; Gutman DA; Huang Z; Burns A; Sebastian NT; Sukhatme V; Lowe MC; Ramalingam SS
• Baricitinib attenuates the proinflammatory phase of COVID-19 driven by lung-infiltrating monocytes.
  Cell Rep Volume: 39 Page(s): 110945
  06/14/2022 Authors: Dobosh B; Zandi K; Giraldo DM; Goh SL; Musall K; Aldeco M; LeCher J; Giacalone VD; Yang J; Eddins DJ
• Effect of Antibiotic Therapy on Immunotherapy Outcomes for Non-Small Cell Lung Cancer: Analysis From the Veterans Health Administration
  Volume: 112 Page(s): E8 - E9
  02/01/2022 Authors: Stokes WA; Behera M; Jiang R; Gutman DA; Huang Z; Burns A; Sebastian N; Sukhatme VV; Lowe M; Ramalingam S
• Concomitant Fibrates and Immunotherapy in Non-Small Cell Lung Cancer Patients in the Veterans Health Administration
  Volume: 16 Page(s): S1128 - S1129
  10/01/2021 Authors: Stokes W; Behera M; Jiang R; Gutman D; Huang Z; Giuste F; Burns A; Sebastian N; Ramalingam S; Sukhatme V
• Visualizing the effects of lactate dehydrogenase (LDH) inhibition and LDH-A genetic ablation in breast and lung cancer with hyperpolarized pyruvate NMR.
  NMR Biomed Volume: 34 Page(s): e4560
  08/01/2021 Authors: Varma G; Seth P; Coutinho de Souza P; Callahan C; Pinto J; Vaidya M; Sonzogni O; Sukhatme V; Wulf GM; Grant AK
• Available drugs and supplements for rapid deployment for treatment of COVID-19.
  J Mol Cell Biol Volume: 13 Page(s): 232 - 236
  07/06/2021 Authors: Cicka D; Sukhatme VP
• Fluvoxamine: A Review of Its Mechanism of Action and Its Role in COVID-19.
  Front Pharmacol Volume: 12 Page(s): 652688
  01/01/2021 Authors: Sukhatme VP; Reiersen AM; Vayttaden SJ; Sukhatme VV
• Reducing injury response to surgery with repurposed drugs: An evolving approach to prevention of cancer metastases.
  Cancer Volume: 126 Page(s): 3916 - 3918
  09/01/2020 Authors: Lowe M; Sukhatme VV; Sukhatme VP
• Utilization patterns of immune checkpoint inhibitors (ICI) for non-small cell lung cancer (NSCLC) within the veterans health administration (VHA).
  Volume: 38
  05/20/2020 Authors: Moghanaki D; Jiang R; Gutman D; Burns A; Sukhatme V; Stokes W; Ramalingam SS; Sukhatme V; Behera M
• Preoperative stimulation of resolution and inflammation blockade eradicates micrometastases.
  J Clin Invest Volume: 129 Page(s): 2964 - 2979
  06/17/2019 Authors: Panigrahy D; Gartung A; Yang J; Yang H; Gilligan MM; Sulciner ML; Bhasin SS; Bielenberg DR; Chang J; Schmidt BA
• Aspirin-triggered proresolving mediators stimulate resolution in cancer.
  Proc Natl Acad Sci U S A Volume: 116 Page(s): 6292 - 6297
  03/26/2019 Authors: Gilligan MM; Gartung A; Sulciner ML; Norris PC; Sukhatme VP; Bielenberg DR; Huang S; Kieran MW; Serhan CN; Panigrahy D
• Suppression of chemotherapy-induced cytokine/lipid mediator surge and ovarian cancer by a dual COX-2/sEH inhibitor.
  Proc Natl Acad Sci U S A Volume: 116 Page(s): 1698 - 1703
  01/29/2019 Authors: Gartung A; Yang J; Sukhatme VP; Bielenberg DR; Fernandes D; Chang J; Schmidt BA; Hwang SH; Zurakowski D; Huang S
• Repurposing Food and Drug Administration-Approved Drugs to Promote Antitumor Immunity.
  Cancer J Volume: 25 Page(s): 88 - 99
  01/01/2019 Authors: Sukhatme VV; Ramalingam SS; Ahmed R; Sukhatme VP
• Introduction: Repurposed Drugs: Teaching an Old Dog New Tricks.
  Cancer J Volume: 25 Page(s): 81
  01/01/2019 Authors: Sukhatme VP
• Chemotherapy-generated cell debris stimulates colon carcinoma tumor growth via osteopontin.
  FASEB J Volume: 33 Page(s): 114 - 125
  01/01/2019 Authors: Chang J; Bhasin SS; Bielenberg DR; Sukhatme VP; Bhasin M; Huang S; Kieran MW; Panigrahy D
• Immuno-modulatory activity of BPM31510 supports T cell viability, proliferation, and function while reversing early signs of exhaustion
  Volume: 78
  07/01/2018 Authors: Nastke M; Kazerounian S; Gaur N; Jayashankar S; Linsenmayer D; Spencer C; Nambiar A; Sarma A; Diers AR; Gesta S
• Resolvins suppress tumor growth and enhance cancer therapy.
  J Exp Med Volume: 215 Page(s): 115 - 140
  01/02/2018 Authors: Sulciner ML; Serhan CN; Gilligan MM; Mudge DK; Chang J; Gartung A; Lehner KA; Bielenberg DR; Schmidt B; Dalli J
• ReDO_DB: the repurposing drugs in oncology database.
  Ecancermedicalscience Volume: 12 Page(s): 886
  01/01/2018 Authors: Pantziarka P; Verbaanderd C; Sukhatme V; Rica Capistrano I; Crispino S; Gyawali B; Rooman I; Van Nuffel AM; Meheus L; Sukhatme VP
• Repurposing drugs in oncology (ReDO)-selective PDE5 inhibitors as anti-cancer agents.
  Ecancermedicalscience Volume: 12 Page(s): 824
  01/01/2018 Authors: Pantziarka P; Sukhatme V; Crispino S; Bouche G; Meheus L; Sukhatme VP
• Citrate Suppresses Tumor Growth in Multiple Models through Inhibition of Glycolysis, the Tricarboxylic Acid Cycle and the IGF-1R Pathway.
  Sci Rep Volume: 7 Page(s): 4537
  07/03/2017 Authors: Ren J-G; Seth P; Ye H; Guo K; Hanai J-I; Husain Z; Sukhatme VP
• Structure-based design of ATP citrate lyase inhibitors and their anticancer activities
  Volume: 253
  04/02/2017 Authors: Jernigan F; Koerner S; Hanai J-I; Sukhatme V; Sun L
• Discovery of furan carboxylate derivatives as novel inhibitors of ATP-citrate lyase via virtual high-throughput screening.
  Bioorg Med Chem Lett Volume: 27 Page(s): 929 - 935
  02/15/2017 Authors: Jernigan FE; Hanai J-I; Sukhatme VP; Sun L
• Design and synthesis of emodin derivatives as novel inhibitors of ATP-citrate lyase.
  Eur J Med Chem Volume: 126 Page(s): 920 - 928
  01/27/2017 Authors: Koerner SK; Hanai J-I; Bai S; Jernigan FE; Oki M; Komaba C; Shuto E; Sukhatme VP; Sun L
• Low-Dose Farnesyltransferase Inhibitor Suppresses HIF-1 and Snail Expression in Triple-Negative Breast Cancer MDA-MB-231 Cells In Vitro.
  J Cell Physiol Volume: 232 Page(s): 192 - 201
  01/01/2017 Authors: Tanaka T; Ikegami Y; Nakazawa H; Kuriyama N; Oki M; Hanai J-I; Sukhatme VP; Kaneki M
• Adipose-derived aldehyde dehydrogenase-expressing cells promote dermal regenerative potential with collagen-glycosaminoglycan scaffold.
  Wound Repair Regen Volume: 25 Page(s): 109 - 119
  01/01/2017 Authors: Matsumine H; Numakura K; Tsunoda S; Wang H; Matsumine R; Climov M; Giatsidis G; Sukhatme VP; Orgill DP
• Repurposing Drugs in Oncology (ReDO)-chloroquine and hydroxychloroquine as anti-cancer agents.
  Ecancermedicalscience Volume: 11 Page(s): 781
  01/01/2017 Authors: Verbaanderd C; Maes H; Schaaf MB; Sukhatme VP; Pantziarka P; Sukhatme V; Agostinis P; Bouche G
• Selective spectroscopic imaging of hyperpolarized pyruvate and its metabolites using a single-echo variable phase advance method in balanced SSFP.
  Magn Reson Med Volume: 76 Page(s): 1102 - 1115
  10/01/2016 Authors: Varma G; Wang X; Vinogradov E; Bhatt RS; Sukhatme VP; Seth P; Lenkinski RE; Alsop DC; Grant AK
• Functional interactions of the cystine/glutamate antiporter, CD44v and MUC1-C oncoprotein in triple-negative breast cancer cells.
  Oncotarget Volume: 7 Page(s): 11756 - 11769
  03/15/2016 Authors: Hasegawa M; Takahashi H; Rajabi H; Alam M; Suzuki Y; Yin L; Tagde A; Maeda T; Hiraki M; Sukhatme VP
• Repurposing Drugs in Oncology (ReDO)-diclofenac as an anti-cancer agent.
  Ecancermedicalscience Volume: 10 Page(s): 610
  01/01/2016 Authors: Pantziarka P; Sukhatme V; Bouche G; Meheus L; Sukhatme VP
• Repurposing Drugs in Oncology (ReDO)-Propranolol as an anti-cancer agent.
  Ecancermedicalscience Volume: 10 Page(s): 680
  01/01/2016 Authors: Pantziarka P; Bouche G; Sukhatme V; Meheus L; Rooman I; Sukhatme VP
• A Case of Complete and Durable Molecular Remission of Chronic Lymphocytic Leukemia Following Treatment with Epigallocatechin-3-gallate, an Extract of Green Tea.
  Cureus Volume: 7 Page(s): e441
  12/29/2015 Authors: Lemanne D; Block KI; Kressel BR; Sukhatme VP; White JD
• Drug repurposing in oncology--patient and health systems opportunities.
  Nat Rev Clin Oncol Volume: 12 Page(s): 732 - 742
  12/01/2015 Authors: Bertolini F; Sukhatme VP; Bouche G
• Erratum to: Modeling precision treatment of breast cancer.
  Genome Biol Volume: 16 Page(s): 95
  05/12/2015 Authors: Daemen A; Griffith OL; Heiser LM; Wang NJ; Enache OM; Sanborn Z; Pepin F; Durinck S; Korkola JE; Griffith M
• Repurposing drugs in your medicine cabinet: untapped opportunities for cancer therapy?
  Future Oncol Volume: 11 Page(s): 181 - 184
  01/01/2015 Authors: Pantziarka P; Bouche G; Meheus L; Sukhatme V; Sukhatme VP
• Repurposing Drugs in Oncology (ReDO)-itraconazole as an anti-cancer agent.
  Ecancermedicalscience Volume: 9 Page(s): 521
  01/01/2015 Authors: Pantziarka P; Sukhatme V; Bouche G; Meheus L; Sukhatme VP
• Repurposing Drugs in Oncology (ReDO)-nitroglycerin as an anti-cancer agent.
  Ecancermedicalscience Volume: 9 Page(s): 568
  01/01/2015 Authors: Sukhatme V; Bouche G; Meheus L; Sukhatme VP; Pantziarka P
• Repurposing Drugs in Oncology (ReDO)-clarithromycin as an anti-cancer agent.
  Ecancermedicalscience Volume: 9 Page(s): 513
  01/01/2015 Authors: Van Nuffel AM; Sukhatme V; Pantziarka P; Meheus L; Sukhatme VP; Bouche G
• Knockdown of malic enzyme 2 suppresses lung tumor growth, induces differentiation and impacts PI3K/AKT signaling.
  Sci Rep Volume: 4 Page(s): 5414
  06/24/2014 Authors: Ren J-G; Seth P; Clish CB; Lorkiewicz PK; Higashi RM; Lane AN; Fan TW-M; Sukhatme VP
• Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells.
  Cell Metab Volume: 19 Page(s): 795 - 809
  05/06/2014 Authors: Xie H; Hanai J-I; Ren J-G; Kats L; Burgess K; Bhargava P; Signoretti S; Billiard J; Duffy KJ; Grant A
• The Repurposing Drugs in Oncology (ReDO) Project.
  Ecancermedicalscience Volume: 8 Page(s): 442
  01/01/2014 Authors: Pantziarka P; Bouche G; Meheus L; Sukhatme V; Sukhatme VP; Vikas P
• Repurposing Drugs in Oncology (ReDO)-mebendazole as an anti-cancer agent.
  Ecancermedicalscience Volume: 8 Page(s): 443
  01/01/2014 Authors: Pantziarka P; Bouche G; Meheus L; Sukhatme V; Sukhatme VP
• Repurposing drugs in oncology (ReDO)-cimetidine as an anti-cancer agent.
  Ecancermedicalscience Volume: 8 Page(s): 485
  01/01/2014 Authors: Pantziarka P; Bouche G; Meheus L; Sukhatme V; Sukhatme VP
• Cancer Biomarkers Minimal and Noninvasive Early Diagnosis and Prognosis Foreword
  Page(s): XI - XI
  01/01/2014 Authors: Sukhatme VP
• Carbon monoxide expedites metabolic exhaustion to inhibit tumor growth.
  Cancer Res Volume: 73 Page(s): 7009 - 7021
  12/01/2013 Authors: Wegiel B; Gallo D; Csizmadia E; Harris C; Belcher J; Vercellotti GM; Penacho N; Seth P; Sukhatme V; Ahmed A
• One-step purification of soluble recombinant human 6-phosphogluconate dehydrogenase from Escherichia coli.
  Protein Expr Purif Volume: 92 Page(s): 62 - 66
  11/01/2013 Authors: Chan B; Sukhatme VP
• Tumor-derived lactate and myeloid-derived suppressor cells: Linking metabolism to cancer immunology.
  Oncoimmunology Volume: 2 Page(s): e26383
  11/01/2013 Authors: Husain Z; Seth P; Sukhatme VP
• 6-Phosphogluconate dehydrogenase regulates tumor cell migration in vitro by regulating receptor tyrosine kinase c-Met.
  Biochem Biophys Res Commun Volume: 439 Page(s): 247 - 251
  09/20/2013 Authors: Chan B; VanderLaan PA; Sukhatme VP
• Tumor-derived lactate modifies antitumor immune response: effect on myeloid-derived suppressor cells and NK cells.
  J Immunol Volume: 191 Page(s): 1486 - 1495
  08/01/2013 Authors: Husain Z; Huang Y; Seth P; Sukhatme VP
• ATP citrate lyase knockdown impacts cancer stem cells in vitro.
  Cell Death Dis Volume: 4 Page(s): e696
  06/27/2013 Authors: Hanai J-I; Doro N; Seth P; Sukhatme VP
• Conversion of peripheral blood NK cells to a decidual NK-like phenotype by a cocktail of defined factors.
  J Immunol Volume: 190 Page(s): 3939 - 3948
  04/15/2013 Authors: Cerdeira AS; Rajakumar A; Royle CM; Lo A; Husain Z; Thadhani RI; Sukhatme VP; Karumanchi SA; Kopcow HD
• Predicting the cost and pace of pharmacogenomic advances: an evidence-based study.
  Clin Chem Volume: 59 Page(s): 649 - 657
  04/01/2013 Authors: Arnaout R; Buck TP; Roulette P; Sukhatme VP
• Modeling precision treatment of breast cancer.
  Genome Biol Volume: 14 Page(s): R110
  01/01/2013 Authors: Daemen A; Griffith OL; Heiser LM; Wang NJ; Enache OM; Sanborn Z; Pepin F; Durinck S; Korkola JE; Griffith M
• Reduction of breast cancer relapses with perioperative non-steroidal anti-inflammatory drugs: new findings and a review.
  Curr Med Chem Volume: 20 Page(s): 4163 - 4176
  01/01/2013 Authors: Retsky M; Demicheli R; Hrushesky WJM; Forget P; De Kock M; Gukas I; Rogers RA; Baum M; Sukhatme V; Vaidya JS
• Disordered purinergic signaling and abnormal cellular metabolism are associated with development of liver cancer in Cd39/ENTPD1 null mice.
  Hepatology Volume: 57 Page(s): 205 - 216
  01/01/2013 Authors: Sun X; Han L; Seth P; Bian S; Li L; Csizmadia E; Junger WG; Schmelzle M; Usheva A; Tapper EB
• Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence.
  FEBS Lett Volume: 586 Page(s): 2389 - 2395
  07/30/2012 Authors: Sukhatme VP; Chan B
• Inhibition of lung cancer growth: ATP citrate lyase knockdown and statin treatment leads to dual blockade of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase (PI3K)/AKT pathways.
  J Cell Physiol Volume: 227 Page(s): 1709 - 1720
  04/01/2012 Authors: Hanai J-I; Doro N; Sasaki AT; Kobayashi S; Cantley LC; Seth P; Sukhatme VP
• A small-molecule screening strategy to identify suppressors of statin myopathy.
  ACS Chem Biol Volume: 6 Page(s): 900 - 904
  09/16/2011 Authors: Wagner BK; Gilbert TJ; Hanai J-I; Imamura S; Bodycombe NE; Bon RS; Waldmann H; Clemons PA; Sukhatme VP; Mootha VK
• Increased mobilisation of circulating endothelial progenitors in von Hippel-Lindau disease and renal cell carcinoma.
  Br J Cancer Volume: 105 Page(s): 112 - 117
  06/28/2011 Authors: Bhatt RS; Zurita AJ; O'Neill A; Norden-Zfoni A; Zhang L; Wu HK; Wen PY; George D; Sukhatme VP; Atkins MB
• On-target inhibition of tumor fermentative glycolysis as visualized by hyperpolarized pyruvate.
  Neoplasia Volume: 13 Page(s): 60 - 71
  01/01/2011 Authors: Seth P; Grant A; Tang J; Vinogradov E; Wang X; Lenkinski R; Sukhatme VP
• Hypoxia and TGF-beta 1 Turn NK Cells into Cells with Enhanced Angiogenic Potential and Limited Cytotoxicity
  Volume: 19 Page(s): 1788 - 1788
  10/01/2010 Authors: Kopcow HD; Cerdeira S; Husain Z; Stillman I; Lo A; Royle C; Thadhani R; Sukhatme V; Karumanchi A
• Induction of erythroid differentiation in human erythroleukemia cells by depletion of malic enzyme 2.
  PLoS One Volume: 5
  09/02/2010 Authors: Ren J-G; Seth P; Everett P; Clish CB; Sukhatme VP
• Plasma angiopoietin-2 (ANG2) as an angiogenic biomarker in renal cell carcinoma (RCC)
  Volume: 28
  05/20/2010 Authors: Bullock AJ; Zhang L; O'Neill AM; Percy A; Sukhatme V; Mier JW; Atkins MB; Bhatt RS
• A phase 2 pilot trial of low-dose, continuous infusion, or "metronomic" paclitaxel and oral celecoxib in patients with metastatic melanoma.
  Cancer Volume: 116 Page(s): 1751 - 1756
  04/01/2010 Authors: Bhatt RS; Merchan J; Parker R; Wu H-K; Zhang L; Seery V; Heymach JV; Atkins MB; McDermott D; Sukhatme VP
• Statin-induced muscle damage and atrogin-1 induction is the result of a geranylgeranylation defect.
  FASEB J Volume: 23 Page(s): 2844 - 2854
  09/01/2009 Authors: Cao P; Hanai J-I; Tanksale P; Imamura S; Sukhatme VP; Lecker SH
• Drug discovery. Repurposing with a difference.
  Science Volume: 324 Page(s): 1394 - 1395
  06/12/2009 Authors: Boguski MS; Mandl KD; Sukhatme VP
• Suppression of Tie-1 in endothelial cells in vitro induces a change in the genome-wide expression profile reflecting an inflammatory function.
  FEBS Lett Volume: 583 Page(s): 1023 - 1028
  03/18/2009 Authors: Chan B; Sukhatme VP
• Receptor tyrosine kinase EphA2 mediates thrombin-induced upregulation of ICAM-1 in endothelial cells in vitro.
  Thromb Res Volume: 123 Page(s): 745 - 752
  03/01/2009 Authors: Chan B; Sukhatme VP
• LDH-A inhibition, a therapeutic strategy for treatment of hereditary leiomyomatosis and renal cell cancer.
  Mol Cancer Ther Volume: 8 Page(s): 626 - 635
  03/01/2009 Authors: Xie H; Valera VA; Merino MJ; Amato AM; Signoretti S; Linehan WM; Sukhatme VP; Seth P
• Neutrophil gelatinase-associated lipocalin suppresses cyst growth by Pkd1 null cells in vitro and in vivo.
  Kidney Int Volume: 74 Page(s): 1310 - 1318
  11/01/2008 Authors: Wei F; Karihaloo A; Yu Z; Marlier A; Seth P; Shibazaki S; Wang T; Sukhatme VP; Somlo S; Cantley LG
• Hypoxia-inducible factor-2alpha: effect on radiation sensitivity and differential regulation by an mTOR inhibitor.
  BJU Int Volume: 102 Page(s): 358 - 363
  08/01/2008 Authors: Bhatt RS; Landis DM; Zimmer M; Torregrossa J; Chen S; Sukhatme VP; Iliopoulos O; Balk S; Bubley GJ
• Receptor tyrosine kinase Tie-1 overexpression in endothelial cells upregulates adhesion molecules.
  Biochem Biophys Res Commun Volume: 371 Page(s): 475 - 479
  07/04/2008 Authors: Chan B; Yuan H-T; Ananth Karumanchi S; Sukhatme VP
• Circulating angiopoietin 2 correlates with mortality in a surgical population with acute lung injury/adult respiratory distress syndrome.
  Shock Volume: 29 Page(s): 656 - 661
  06/01/2008 Authors: Gallagher DC; Parikh SM; Balonov K; Miller A; Gautam S; Talmor D; Sukhatme VP
• A national course for renal fellows: the origins of renal physiology.
  J Am Soc Nephrol Volume: 19 Page(s): 649 - 650
  04/01/2008 Authors: Zeidel M; Bonventre J; Forrest J; Sukhatme V
• Admission angiopoietin levels in children with septic shock.
  Shock Volume: 28 Page(s): 650 - 654
  12/01/2007 Authors: Giuliano JS; Lahni PM; Harmon K; Wong HR; Doughty LA; Carcillo JA; Zingarelli B; Sukhatme VP; Parikh SM; Wheeler DS
• The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity.
  J Clin Invest Volume: 117 Page(s): 3940 - 3951
  12/01/2007 Authors: Hanai J-I; Cao P; Tanksale P; Imamura S; Koshimizu E; Zhao J; Kishi S; Yamashita M; Phillips PS; Sukhatme VP
• Activation of the orphan endothelial receptor Tie1 modifies Tie2-mediated intracellular signaling and cell survival.
  FASEB J Volume: 21 Page(s): 3171 - 3183
  10/01/2007 Authors: Yuan HT; Venkatesha S; Chan B; Deutsch U; Mammoto T; Sukhatme VP; Woolf AS; Karumanchi SA
• Angiopoietin-1 requires p190 RhoGAP to protect against vascular leakage in vivo.
  J Biol Chem Volume: 282 Page(s): 23910 - 23918
  08/17/2007 Authors: Mammoto T; Parikh SM; Mammoto A; Gallagher D; Chan B; Mostoslavsky G; Ingber DE; Sukhatme VP
• Combination of radiofrequency ablation with antiangiogenic therapy for tumor ablation efficacy: study in mice.
  Radiology Volume: 244 Page(s): 464 - 470
  08/01/2007 Authors: Hakim A; Hines-Peralta A; Peddi H; Atkins MB; Sukhatme VP; Signoretti S; Regan M; Goldberg SN
• Angiopoietin 2 is a potential mediator of high-dose interleukin 2-induced vascular leak.
  Clin Cancer Res Volume: 13 Page(s): 2115 - 2120
  04/01/2007 Authors: Gallagher DC; Bhatt RS; Parikh SM; Patel P; Seery V; McDermott DF; Atkins MB; Sukhatme VP
• Biomarkers for monitoring antiangiogenic therapy.
  Clin Cancer Res Volume: 13 Page(s): 777s - 780s
  01/15/2007 Authors: Bhatt RS; Seth P; Sukhatme VP
• Innovations and challenges in renal cell carcinoma: summary statement from the Second Cambridge Conference.
  Clin Cancer Res Volume: 13 Page(s): 667s - 670s
  01/15/2007 Authors: Atkins MB; Ernstoff MS; Figlin RA; Flaherty KT; George DJ; Kaelin WG; Kwon ED; Libermann TA; Linehan WM; McDermott DF
• Circulating angiopoietin 2 correlates with mortality in a surgical population with ALI/ARDS.
  Volume: 34 Page(s): A28 - A28
  12/01/2006 Authors: Gallagher DC; Parikh SM; Sukhatme VP; Balonov K; Talmor D; Miller A
• Admission angiopoietin-2 levels in children with septic shock.
  Volume: 34 Page(s): A1 - A1
  12/01/2006 Authors: Giuliano JS; Lahni PM; Wong HR; Wheeler DS; Sukhatme VP; Gallagher D; Parikh SM; Carcillo JA
• Nephrocan, a novel member of the small leucine-rich repeat protein family, is an inhibitor of transforming growth factor-beta signaling.
  J Biol Chem Volume: 281 Page(s): 36044 - 36051
  11/24/2006 Authors: Mochida Y; Parisuthiman D; Kaku M; Hanai J-I; Sukhatme VP; Yamauchi M
• Angiopoeitin 2 is a potential mediator of high-dose interleukin 2 induced vascular leak
  Volume: 29 Page(s): 638 - 638
  11/01/2006 Authors: Bhatt RS; Gallagher DC; Seery V; Parikh SM; Patel P; McDermott DF; Atkins MB; Sukhatme VP
• Lipocalin 2 antagonizes the proangiogenic action of ras in transformed cells.
  Mol Cancer Res Volume: 4 Page(s): 821 - 829
  11/01/2006 Authors: Venkatesha S; Hanai J-I; Seth P; Karumanchi SA; Sukhatme VP
• Circulating tumor cells and endothelial cells can be easily quantitated in renal cell carcinoma patients using a semi-automated system
  Volume: 108 Page(s): 347 - 347
  10/25/2006 Authors: Lomo L; Seth P; Whitman T; Sukhatme V; Cibas E
• A novel endothelial-specific heat shock protein HspA12B is required in both zebrafish development and endothelial functions in vitro.
  J Cell Sci Volume: 119 Page(s): 4117 - 4126
  10/01/2006 Authors: Hu G; Tang J; Zhang B; Lin Y; Hanai J-I; Galloway J; Bedell V; Bahary N; Han Z; Ramchandran R
• Improved tumor destruction with arsenic trioxide and radiofrequency ablation in three animal models.
  Radiology Volume: 240 Page(s): 82 - 89
  07/01/2006 Authors: Hines-Peralta A; Sukhatme V; Regan M; Signoretti S; Liu Z-J; Goldberg SN
• A phase II pilot trial of low dose, continuous infusion, or "metronomic", paclitaxel and oral celecoxib in patients with metastatic melanoma.
  Volume: 24 Page(s): 455S - 455S
  06/20/2006 Authors: McDermott DF; Cho DC; Merchan JR; Bhatt RS; Seery V; Mosher JL; Farquhar MB; Mier JW; Atkins MB; Sukhatme VP
• Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model.
  J Natl Cancer Inst Volume: 98 Page(s): 756 - 764
  06/07/2006 Authors: Merchan JR; Tang J; Hu G; Lin Y; Mutter W; Tong C; Karumanchi SA; Russell SJ; Sukhatme VP
• Soluble endoglin contributes to the pathogenesis of preeclampsia.
  Nat Med Volume: 12 Page(s): 642 - 649
  06/01/2006 Authors: Venkatesha S; Toporsian M; Lam C; Hanai J-I; Mammoto T; Kim YM; Bdolah Y; Lim K-H; Yuan H-T; Libermann TA
• Hemodialysis vascular access dysfunction: a cellular and molecular viewpoint.
  J Am Soc Nephrol Volume: 17 Page(s): 1112 - 1127
  04/01/2006 Authors: Roy-Chaudhury P; Sukhatme VP; Cheung AK
• A critical role for calponin 2 in vascular development.
  J Biol Chem Volume: 281 Page(s): 6664 - 6672
  03/10/2006 Authors: Tang J; Hu G; Hanai J-I; Yadlapalli G; Lin Y; Zhang B; Galloway J; Bahary N; Sinha S; Thisse B
• Excess circulating angiopoietin-2 may contribute to pulmonary vascular leak in sepsis in humans.
  PLoS Med Volume: 3 Page(s): e46
  03/01/2006 Authors: Parikh SM; Mammoto T; Schultz A; Yuan H-T; Christiani D; Karumanchi SA; Sukhatme VP
• IGFBP5: A novel marker of preeclampsia complicated by IUGR.
  Volume: 25 Page(s): 117 - 117
  01/01/2006 Authors: Tjoa ML; O Alemann J; Maynard S; Ramoni M; Lim KH; Libermann T; Sukhatme VP; Karumanchi SA
• Magic roundabout, a tumor endothelial marker: expression and signaling.
  Biochem Biophys Res Commun Volume: 332 Page(s): 533 - 541
  07/01/2005 Authors: Seth P; Lin Y; Hanai J-I; Shivalingappa V; Duyao MP; Sukhatme VP
• Preeclampsia: a renal perspective.
  Kidney Int Volume: 67 Page(s): 2101 - 2113
  06/01/2005 Authors: Karumanchi SA; Maynard SE; Stillman IE; Epstein FH; Sukhatme VP
• roundabout4 is essential for angiogenesis in vivo.
  Proc Natl Acad Sci U S A Volume: 102 Page(s): 6373 - 6378
  05/03/2005 Authors: Bedell VM; Yeo S-Y; Park KW; Chung J; Seth P; Shivalingappa V; Zhao J; Obara T; Sukhatme VP; Drummond IA
• Lipocalin 2 diminishes invasiveness and metastasis of Ras-transformed cells.
  J Biol Chem Volume: 280 Page(s): 13641 - 13647
  04/08/2005 Authors: Hanai J-I; Mammoto T; Seth P; Mori K; Karumanchi SA; Barasch J; Sukhatme VP
• Coley's toxin revisited: immunotherapy or plasminogen activator therapy of cancer?
  J Thromb Haemost Volume: 3 Page(s): 424 - 427
  03/01/2005 Authors: Zacharski LR; Sukhatme VP
• Microarray analysis of in vitro pericyte differentiation reveals an angiogenic program of gene expression.
  FASEB J Volume: 19 Page(s): 270 - 271
  02/01/2005 Authors: Kale S; Hanai J-I; Chan B; Karihaloo A; Grotendorst G; Cantley L; Sukhatme VP
• Increased endothelial uptake of paclitaxel as a potential mechanism for its antiangiogenic effects: potentiation by Cox-2 inhibition.
  Int J Cancer Volume: 113 Page(s): 490 - 498
  01/20/2005 Authors: Merchan JR; Jayaram DR; Supko JG; He X; Bubley GJ; Sukhatme VP
• Urinary placental growth factor and risk of preeclampsia.
  JAMA Volume: 293 Page(s): 77 - 85
  01/05/2005 Authors: Levine RJ; Thadhani R; Qian C; Lam C; Lim K-H; Yu KF; Blink AL; Sachs BP; Epstein FH; Sibai BM
• Critical roles of CD146 in zebrafish vascular development.
  Dev Dyn Volume: 232 Page(s): 232 - 244
  01/01/2005 Authors: Chan B; Sinha S; Cho D; Ramchandran R; Sukhatme VP
• Preeclampsia and future cardiovascular disease: potential role of altered angiogenesis and insulin resistance.
  J Clin Endocrinol Metab Volume: 89 Page(s): 6239 - 6243
  12/01/2004 Authors: Wolf M; Hubel CA; Lam C; Sampson M; Ecker JL; Ness RB; Rajakumar A; Daftary A; Shakir ASM; Seely EW
• Urinary placental growth factor (PGF) and the risk of preeclampsia
  Volume: 191 Page(s): S6 - S6
  12/01/2004 Authors: Levine R; Thadhani R; Qian C; Lam C; Lim KH; Yu K; Blink A; Sachs B; Epstein F; Sibai B
• Angiogenic imbalance in the pathophysiology of preeclampsia: newer insights.
  Semin Nephrol Volume: 24 Page(s): 548 - 556
  11/01/2004 Authors: Bdolah Y; Sukhatme VP; Karumanchi SA
• Insulin resistance and alterations in angiogenesis: additive insults that may lead to preeclampsia.
  Hypertension Volume: 43 Page(s): 988 - 992
  05/01/2004 Authors: Thadhani R; Ecker JL; Mutter WP; Wolf M; Smirnakis KV; Sukhatme VP; Levine RJ; Karumanchi SA
• Transforming growth factor-beta1 inhibition of vascular smooth muscle cell activation is mediated via Smad3.
  J Biol Chem Volume: 279 Page(s): 16388 - 16393
  04/16/2004 Authors: Feinberg MW; Watanabe M; Lebedeva MA; Depina AS; Hanai J-I; Mammoto T; Frederick JP; Wang X-F; Sukhatme VP; Jain MK
• Preeclampsia and future cardiovascular disease: Potential role of altered angiogenesis and insulin resistance.
  Volume: 52 Page(s): S382 - S383
  03/01/2004 Authors: Wolf M; Hubel CA; Seely EW; Roberts JM; Sukhatme VP; Karumanchi SA; Thadhani R
• Circulating angiogenic factors and the risk of preeclampsia.
  N Engl J Med Volume: 350 Page(s): 672 - 683
  02/12/2004 Authors: Levine RJ; Maynard SE; Qian C; Lim K-H; England LJ; Yu KF; Schisterman EF; Thadhani R; Sachs BP; Epstein FH
• First trimester placental growth factor and soluble fms-like tyrosine kinase 1 and risk for preeclampsia.
  J Clin Endocrinol Metab Volume: 89 Page(s): 770 - 775
  02/01/2004 Authors: Thadhani R; Mutter WP; Wolf M; Levine RJ; Taylor RN; Sukhatme VP; Ecker J; Karumanchi SA
• Acute rise in circulating SFLT-1 may herald preeclampsia
  Volume: 189 Page(s): S57 - S57
  12/01/2003 Authors: Levine R; Maynard S; Qian C; Lim KH; England L; Yu K; Schisterman E; Thadhani R; Sachs B; Epstein F
• Relaxin increases ubiquitin-dependent degradation of fibronectin in vitro and ameliorates renal fibrosis in vivo.
  Am J Physiol Renal Physiol Volume: 285 Page(s): F59 - F67
  07/01/2003 Authors: McDonald GA; Sarkar P; Rennke H; Unemori E; Kalluri R; Sukhatme VP
• Antiangiogenic property of human thrombin.
  Microvasc Res Volume: 66 Page(s): 1 - 14
  07/01/2003 Authors: Chan B; Merchan JR; Kale S; Sukhatme VP
• In vitro and in vivo induction of antiangiogenic activity by plasminogen activators and captopril.
  J Natl Cancer Inst Volume: 95 Page(s): 388 - 399
  03/05/2003 Authors: Merchan JR; Chan B; Kale S; Schnipper LE; Sukhatme VP
• A refined understanding of immunosuppressives and cancer risk.
  Kidney Int Volume: 63 Page(s): 1160 - 1161
  03/01/2003 Authors: Strom TB; Sukhatme VP
• Excess placental soluble fms-like tyrosine kinase 1 (sFlt1) may contribute to endothelial dysfunction, hypertension, and proteinuria in preeclampsia.
  J Clin Invest Volume: 111 Page(s): 649 - 658
  03/01/2003 Authors: Maynard SE; Min J-Y; Merchan J; Lim K-H; Li J; Mondal S; Libermann TA; Morgan JP; Sellke FW; Stillman IE
• Sflt-1, a circulating VEGF antagonist, is up-regulated in preeclampsia and contributes to endothelial dysfunction.
  Volume: 13 Page(s): 58A - 58A
  09/01/2002 Authors: Maynard SE; Merchan J; Epstein FH; Sukhatme VP; Karumanchi SA
• Endostatin is a potential inhibitor of Wnt signaling.
  J Cell Biol Volume: 158 Page(s): 529 - 539
  08/05/2002 Authors: Hanai J-I; Gloy J; Karumanchi SA; Kale S; Tang J; Hu G; Chan B; Ramchandran R; Jha V; Sukhatme VP
• A system for the enhancement of adenovirus mediated gene transfer to uro-epithelium.
  J Urol Volume: 168 Page(s): 813 - 818
  08/01/2002 Authors: Lin L-F; Zhu G; Yoo JJ; Soker S; Sukhatme VP; Atala A
• Endostatin causes G1 arrest of endothelial cells through inhibition of cyclin D1.
  J Biol Chem Volume: 277 Page(s): 16464 - 16469
  05/10/2002 Authors: Hanai J-I; Dhanabal M; Karumanchi SA; Albanese C; Waterman M; Chan B; Ramchandran R; Pestell R; Sukhatme VP
• Renal cancer: molecular mechanisms and newer therapeutic options.
  Curr Opin Nephrol Hypertens Volume: 11 Page(s): 37 - 42
  01/01/2002 Authors: Karumanchi SA; Merchan J; Sukhatme VP
• Cellular actions and signaling by endostatin.
  Crit Rev Eukaryot Gene Expr Volume: 12 Page(s): 175 - 191
  01/01/2002 Authors: Ramchandran R; Karumanchi SA; Hanai J-I; Alper SL; Sukhatme VP
• Endostatin regulates branching morphogenesis of renal epithelial cells and ureteric bud.
  Proc Natl Acad Sci U S A Volume: 98 Page(s): 12509 - 12514
  10/23/2001 Authors: Karihaloo A; Karumanchi SA; Barasch J; Jha V; Nickel CH; Yang J; Grisaru S; Bush KT; Nigam S; Rosenblum ND
• Activation of vitamin D receptor by the Wilms' tumor gene product mediates apoptosis of renal cells.
  J Am Soc Nephrol Volume: 12 Page(s): 1188 - 1196
  06/01/2001 Authors: Wagner K-D; Wagner N; Sukhatme VP; Scholz H
• Intracellular Ca(2+) signaling in endothelial cells by the angiogenesis inhibitors endostatin and angiostatin.
  Am J Physiol Cell Physiol Volume: 280 Page(s): C1140 - C1150
  05/01/2001 Authors: Jiang L; Jha V; Dhanabal M; Sukhatme VP; Alper SL
• VHL tumor suppressor regulates Cl-/HCO3- exchange and Na+/H+ exchange activities in renal carcinoma cells.
  Physiol Genomics Volume: 5 Page(s): 119 - 128
  04/02/2001 Authors: Karumanchi SA; Jiang L; Knebelmann B; Stuart-Tilley AK; Alper SL; Sukhatme VP
• Cell surface glypicans are low-affinity endostatin receptors.
  Mol Cell Volume: 7 Page(s): 811 - 822
  04/01/2001 Authors: Karumanchi SA; Jha V; Ramchandran R; Karihaloo A; Tsiokas L; Chan B; Dhanabal M; Hanai JI; Venkataraman G; Shriver Z
• Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents.
  Nature Volume: 408 Page(s): 990 - 994
  12/21/2000 Authors: Hanaoka K; Qian F; Boletta A; Bhunia AK; Piontek K; Tsiokas L; Sukhatme VP; Guggino WB; Germino GG
• Effect of endostatin on spontaneous tumorigenesis of mammary adenocarcinoma in a transgenic mouse model.
  Cancer Res Volume: 60 Page(s): 4362 - 4365
  08/15/2000 Authors: Yokoyama Y; Green JE; Sukhatme VP; Ramakrishnan S
• Fibrosis and angiogenesis.
  Curr Opin Nephrol Hypertens Volume: 9 Page(s): 413 - 418
  07/01/2000 Authors: Kalluri R; Sukhatme VP
• Angiostatin induces mitotic cell death of proliferating endothelial cells.
  Mol Cell Biol Res Commun Volume: 3 Page(s): 277 - 282
  05/01/2000 Authors: Hari D; Beckett MA; Sukhatme VP; Dhanabal M; Nodzenski E; Lu H; Mauceri HJ; Kufe DW; Weichselbaum RR
• Anti-angiogenic cues from vascular basement membrane collagen.
  Cancer Res Volume: 60 Page(s): 2520 - 2526
  05/01/2000 Authors: Colorado PC; Torre A; Kamphaus G; Maeshima Y; Hopfer H; Takahashi K; Volk R; Zamborsky ED; Herman S; Sarkar PK
• Synergy between angiostatin and endostatin: inhibition of ovarian cancer growth.
  Cancer Res Volume: 60 Page(s): 2190 - 2196
  04/15/2000 Authors: Yokoyama Y; Dhanabal M; Griffioen AW; Sukhatme VP; Ramakrishnan S
• Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth.
  J Biol Chem Volume: 275 Page(s): 1209 - 1215
  01/14/2000 Authors: Kamphaus GD; Colorado PC; Panka DJ; Hopfer H; Ramchandran R; Torre A; Maeshima Y; Mier JW; Sukhatme VP; Kalluri R
• Antitumor interaction of short-course endostatin and ionizing radiation.
  Cancer J Volume: 6 Page(s): 287 - 293
  01/01/2000 Authors: Hanna NN; Seetharam S; Mauceri HJ; Beckett MA; Jaskowiak NT; Salloum RM; Hari D; Dhanabal M; Ramchandran R; Kalluri R
• Training the academic nephrologist for the new millennium.
  Semin Nephrol Volume: 20 Page(s): 87 - 91
  01/01/2000 Authors: Sukhatme VP
• An important von Hippel-Lindau tumor suppressor domain mediates Sp1-binding and self-association.
  Biochem Biophys Res Commun Volume: 266 Page(s): 43 - 50
  12/09/1999 Authors: Cohen HT; Zhou M; Welsh AM; Zarghamee S; Scholz H; Mukhopadhyay D; Kishida T; Zbar B; Knebelmann B; Sukhatme VP
• Interaction between RGS7 and polycystin.
  Proc Natl Acad Sci U S A Volume: 96 Page(s): 6371 - 6376
  05/25/1999 Authors: Kim E; Arnould T; Sellin L; Benzing T; Comella N; Kocher O; Tsiokas L; Sukhatme VP; Walz G
• Kringle 5 causes cell cycle arrest and apoptosis of endothelial cells.
  Biochem Biophys Res Commun Volume: 258 Page(s): 668 - 673
  05/19/1999 Authors: Lu H; Dhanabal M; Volk R; Waterman MJ; Ramchandran R; Knebelmann B; Segal M; Sukhatme VP
• Cloning, expression, and in vitro activity of human endostatin.
  Biochem Biophys Res Commun Volume: 258 Page(s): 345 - 352
  05/10/1999 Authors: Dhanabal M; Volk R; Ramchandran R; Simons M; Sukhatme VP
• Transforming growth factor beta1 is a target for the von Hippel-Lindau tumor suppressor and a critical growth factor for clear cell renal carcinoma.
  Cancer Res Volume: 59 Page(s): 2210 - 2216
  05/01/1999 Authors: Ananth S; Knebelmann B; Grning W; Dhanabal M; Walz G; Stillman IE; Sukhatme VP
• Endostatin induces endothelial cell apoptosis.
  J Biol Chem Volume: 274 Page(s): 11721 - 11726
  04/23/1999 Authors: Dhanabal M; Ramchandran R; Waterman MJ; Lu H; Knebelmann B; Segal M; Sukhatme VP
• Rapid induction and translocation of Egr-1 in response to mechanical strain in vascular smooth muscle cells.
  Circ Res Volume: 84 Page(s): 678 - 687
  04/02/1999 Authors: Morawietz H; Ma YH; Vives F; Wilson E; Sukhatme VP; Holtz J; Ives HE
• Specific association of the gene product of PKD2 with the TRPC1 channel.
  Proc Natl Acad Sci U S A Volume: 96 Page(s): 3934 - 3939
  03/30/1999 Authors: Tsiokas L; Arnould T; Zhu C; Kim E; Walz G; Sukhatme VP
• Antiangiogenic activity of restin, NC10 domain of human collagen XV: comparison to endostatin.
  Biochem Biophys Res Commun Volume: 255 Page(s): 735 - 739
  02/24/1999 Authors: Ramchandran R; Dhanabal M; Volk R; Waterman MJ; Segal M; Lu H; Knebelmann B; Sukhatme VP
• Decreased expression of the pro-apoptotic protein Par-4 in renal cell carcinoma.
  Oncogene Volume: 18 Page(s): 1205 - 1208
  02/04/1999 Authors: Cook J; Krishnan S; Ananth S; Sells SF; Shi Y; Walther MM; Linehan WM; Sukhatme VP; Weinstein MH; Rangnekar VM
• Sp1 and egr-1 have opposing effects on the regulation of the rat Pgp2/mdr1b gene.
  J Biol Chem Volume: 274 Page(s): 3199 - 3206
  01/29/1999 Authors: Thottassery JV; Sun D; Zambetti GP; Troutman A; Sukhatme VP; Schuetz EG; Schuetz JD
• Efficient adenoviral gene transfer to kidney cortical vasculature utilizing a fiber modified vector.
  J Gene Med Volume: 1 Page(s): 103 - 110
  01/01/1999 Authors: McDonald GA; Zhu G; Li Y; Kovesdi I; Wickham TJ; Sukhatme VP
• Endostatin: yeast production, mutants, and antitumor effect in renal cell carcinoma.
  Cancer Res Volume: 59 Page(s): 189 - 197
  01/01/1999 Authors: Dhanabal M; Ramchandran R; Volk R; Stillman IE; Lombardo M; Iruela-Arispe ML; Simons M; Sukhatme VP
• Gene transfer in the kidney.
  Am J Physiol Volume: 276 Page(s): F1 - F9
  01/01/1999 Authors: Kelley VR; Sukhatme VP
• Potentiation of the antitumor effect of ionizing radiation by brief concomitant exposures to angiostatin.
  Cancer Res Volume: 58 Page(s): 5686 - 5689
  12/15/1998 Authors: Gorski DH; Mauceri HJ; Salloum RM; Gately S; Hellman S; Beckett MA; Sukhatme VP; Soff GA; Kufe DW; Weichselbaum RR
• Expression of VHL tumor suppressor in renal carcinoma cells increases mRNA levels of AE-2 and NHE-5 while downregulating corresponding ion exchange activities
  Volume: 9 Page(s): 247A - 247A
  11/01/1998 Authors: Alper SL; Jiang L; Ananth S; Knebelmann B; Gruning W; Stuart-Tilley AK; Sukhatme VP
• Combined effects of angiostatin and ionizing radiation in antitumour therapy.
  Nature Volume: 394 Page(s): 287 - 291
  07/16/1998 Authors: Mauceri HJ; Hanna NN; Beckett MA; Gorski DH; Staba MJ; Stellato KA; Bigelow K; Heimann R; Gately S; Dhanabal M
• Fluid shear stress activation of egr-1 transcription in cultured human endothelial and epithelial cells is mediated via the extracellular signal-related kinase 1/2 mitogen-activated protein kinase pathway.
  J Clin Invest Volume: 101 Page(s): 2540 - 2549
  06/01/1998 Authors: Schwachtgen JL; Houston P; Campbell C; Sukhatme V; Braddock M
• A novel system for the intravesical delivery of adenoviral-mediated genes.
  Volume: 159 Page(s): 145 - 145
  05/01/1998 Authors: Lin LF; Zhu GM; Sukhatme VP; Atala A
• Transforming growth factor alpha is a target for the von Hippel-Lindau tumor suppressor.
  Cancer Res Volume: 58 Page(s): 226 - 231
  01/15/1998 Authors: Knebelmann B; Ananth S; Cohen HT; Sukhatme VP
• Expression of fetal kidney growth factors in a kidney tumor line: role of FGF2 in kidney development.
  Exp Nephrol Volume: 6 Page(s): 522 - 533
  01/01/1998 Authors: Drummond IA; Mukhopadhyay D; Sukhatme VP
• High cell density induces vascular endothelial growth factor expression via protein tyrosine phosphorylation.
  Gene Expr Volume: 7 Page(s): 53 - 60
  01/01/1998 Authors: Mukhopadhyay D; Tsiokas L; Sukhatme VP
• A far upstream cis-element is required for Wilms' tumor-1 (WT1) gene expression in renal cell culture.
  J Biol Chem Volume: 272 Page(s): 32836 - 32846
  12/26/1997 Authors: Scholz H; Bossone SA; Cohen HT; Akella U; Strauss WM; Sukhatme VP
• Adenovirus-mediated beta-galactosidase gene delivery to the liver leads to protein deposition in kidney glomeruli.
  Kidney Int Volume: 52 Page(s): 992 - 999
  10/01/1997 Authors: Zhu G; Nicolson AG; Zheng XX; Strom TB; Sukhatme VP
• A novel system for the enhancement of adenovirus-mediated gene transfer to bladders.
  Volume: 100 Page(s): 550 - 551
  09/01/1997 Authors: Lin LF; Zhu GM; Sukhatme VP; Atala A
• Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2.
  Volume: 8 Page(s): A1766 - A1766
  09/01/1997 Authors: Tsiokas L; Kim E; Arnould T; Sukhatme VP; Walz G
• Enhanced adenoviral gene transfer to kidney vasculature utilizing a fiber modified vector.
  Volume: 8 Page(s): A2334 - A2334
  09/01/1997 Authors: McDonald GA; Zhu GM; Kovesdi I; Wickham TJ; Sukhatme VP
• A critical domain of the von Hippel-Lindau (VHL) tumor suppressor gene product.
  Volume: 8 Page(s): A1792 - A1792
  09/01/1997 Authors: Cohen HT; Zarghamee S; Knebelmann B; Kishida T; Zbar B; Sukhatme VP
• The von Hippel-Lindau (VHL) gene product decreases TGF-alpha mRNA stability in renal carcinoma cells.
  Volume: 8 Page(s): A1807 - A1807
  09/01/1997 Authors: Knebelmann B; Ananth S; Cohen HT; Sukhatme VP
• The von Hippel-Lindau tumor suppressor gene product interacts with Sp1 to repress vascular endothelial growth factor promoter activity.
  Mol Cell Biol Volume: 17 Page(s): 5629 - 5639
  09/01/1997 Authors: Mukhopadhyay D; Knebelmann B; Cohen HT; Ananth S; Sukhatme VP
• Early growth response-1-dependent apoptosis is mediated by p53.
  J Biol Chem Volume: 272 Page(s): 20131 - 20138
  08/08/1997 Authors: Nair P; Muthukkumar S; Sells SF; Han SS; Sukhatme VP; Rangnekar VM
• Expression and function of the leucine zipper protein Par-4 in apoptosis.
  Mol Cell Biol Volume: 17 Page(s): 3823 - 3832
  07/01/1997 Authors: Sells SF; Han SS; Muthukkumar S; Maddiwar N; Johnstone R; Boghaert E; Gillis D; Liu G; Nair P; Monnig S
• Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2.
  Proc Natl Acad Sci U S A Volume: 94 Page(s): 6965 - 6970
  06/24/1997 Authors: Tsiokas L; Kim E; Arnould T; Sukhatme VP; Walz G
• Adenovirus-mediated expression of Fas ligand induces hepatic apoptosis after Systemic administration and apoptosis of ex vivo-infected pancreatic islet allografts and isografts.
  Hum Gene Ther Volume: 8 Page(s): 955 - 963
  05/20/1997 Authors: Muruve DA; Nicolson AG; Manfro RC; Strom TB; Sukhatme VP; Libermann TA
• Sp1 is a critical regulator of the Wilms' tumor-1 gene.
  J Biol Chem Volume: 272 Page(s): 2901 - 2913
  01/31/1997 Authors: Cohen HT; Bossone SA; Zhu G; McDonald GA; Sukhatme VP
• Gene therapy for kidney disease.
  Adv Nephrol Necker Hosp Volume: 26 Page(s): 73 - 80
  01/01/1997 Authors: Sukhatme VP
• Gene transfer into kidney tubules and vasculature by adenoviral vectors.
  Exp Nephrol Volume: 5 Page(s): 137 - 143
  01/01/1997 Authors: Sukhatme VP; Cowley BD; Zhu G
• Immortal, developmentally arrested human fetal kidney cell lines created by retroviral expression of human papilloma virus E6 and E7.
  Exp Nephrol Volume: 5 Page(s): 390 - 398
  01/01/1997 Authors: Drummond IA; Goodyer P; Sukhatme VP
• Transcription factor Egr-1 regulates glomerular mesangial cell proliferation.
  J Biol Chem Volume: 271 Page(s): 28306 - 28310
  11/08/1996 Authors: Hofer G; Grimmer C; Sukhatme VP; Sterzel RB; Rupprecht HD
• Sp1 is a critical regulator of the WT1 gene.
  Volume: 7 Page(s): A1723 - A1723
  09/01/1996 Authors: Cohen HT; Bossone SA; Zhu G; McDonald GA; Sukhatme VP
• The von Hippel-Lindau (VHL) gene product interacts with AP1 to repress vascular endothelial growth factor (VEGF) promoter activity.
  Volume: 7 Page(s): A2072 - A2072
  09/01/1996 Authors: Mukhopadhyay D; Knebelmann B; Cohen HT; Sukhatme VP
• Adenovirus-mediated gene transfer in murine islet transplantation.
  Volume: 7 Page(s): A3212 - A3212
  09/01/1996 Authors: Manfro RC; Muruve DA; Nicholson AG; Choi WH; Zheng XX; Sukhatme VP; Strom TB; Libermann TA
• Adenovirus-mediated beta-galactosidase gene delivery to the liver leads to protein deposition in kidney glomeruli.
  Volume: 7 Page(s): A2521 - A2521
  09/01/1996 Authors: Zhu GM; Nicolson G; Sukhatme VP
• Single mechanical stimulus induces EGR-1 transcription in vascular smooth muscle (VSM) cells.
  Volume: 7 Page(s): A2071 - A2071
  09/01/1996 Authors: Morawietz H; Sukhatme VP; Wilson E; Holtz J; Ives HE
• In vivo adenovirus-mediated gene transfer into normal and cystic rat kidneys.
  Gene Ther Volume: 3 Page(s): 298 - 304
  04/01/1996 Authors: Zhu G; Nicolson AG; Cowley BD; Rosen S; Sukhatme VP
• Vascular access stenosis: prospects for prevention and therapy.
  Kidney Int Volume: 49 Page(s): 1161 - 1174
  04/01/1996 Authors: Sukhatme VP
• C-jun and Egr-1 participate in DNA synthesis and cell survival in response to ionizing radiation exposure.
  J Biol Chem Volume: 270 Page(s): 30303 - 30309
  12/22/1995 Authors: Hallahan DE; Dunphy E; Virudachalam S; Sukhatme VP; Kufe DW; Weichselbaum RR
• LLC-PK1 cell growth is repressed by WT1 inhibition of G-protein alpha i-2 protooncogene transcription.
  J Biol Chem Volume: 270 Page(s): 30760 - 30764
  12/22/1995 Authors: Kinane TB; Finder JD; Kawashima A; Brown D; Abbate M; Fredericks WJ; Sukhatme VP; Rauscher FJ; Ercolani L
• Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression.
  Cancer Res Volume: 55 Page(s): 6161 - 6165
  12/15/1995 Authors: Mukhopadhyay D; Tsiokas L; Sukhatme VP
• Expression patterns of immediate early transcription factors in human non-small cell lung cancer. The Lung Cancer Study Group.
  Oncogene Volume: 11 Page(s): 1261 - 1269
  10/05/1995 Authors: Levin WJ; Press MF; Gaynor RB; Sukhatme VP; Boone TC; Reissmann PT; Figlin RA; Holmes EC; Souza LM; Slamon DJ
• FGF2 EXPRESSION IN KIDNEY DEVELOPMENT - A URETERAL BUD DERIVED MESENCHYMAL CELL MITOGEN
  Volume: 6 Page(s): 693 - 693
  09/01/1995 Authors: DRUMMOND IA; SUKHATME VP
• THE TRANSCRIPTION FACTOR EGR-1 REGULATES MESANGIAL CELL (MC) PROLIFERATION
  Volume: 6 Page(s): 768 - 768
  09/01/1995 Authors: HOFER G; GRIMMER C; SUKHATME VP; STERZEL RB; RUPPRECHT HD
• A PUTATIVE TRANSCRIPTIONAL ACTIVATOR OF THE WT1 GENE
  Volume: 6 Page(s): 692 - 692
  09/01/1995 Authors: COHEN HT; BOSSONE SA; SUKHATME VP
• IN-VIVO ADENOVIRUS-MEDIATED GENE-TRANSFER INTO NORMAL AND CYSTIC RAT KIDNEYS
  Volume: 6 Page(s): 891 - 891
  09/01/1995 Authors: ZHU GM; NICHOLSON AG; COWLEY B; ROSEN S; SUKHATME VP
• Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation.
  Nature Volume: 375 Page(s): 577 - 581
  06/15/1995 Authors: Mukhopadhyay D; Tsiokas L; Zhou XM; Foster D; Brugge JS; Sukhatme VP
• MECHANICAL STRAIN ENHANCES EXPRESSION OF THE PDGF-A AND EGR-1 GENES IN VASCULAR SMOOTH-MUSCLE CELLS
  Volume: 9 Page(s): A1464 - A1464
  04/24/1995 Authors: WILSON E; VIVES G; COLLINS T; SUKHATME V; IVES HE
• Enzymatic detection systems for non-isotopic in situ hybridization using biotinylated cDNA probes.
  Histochem J Volume: 27 Page(s): 280 - 290
  04/01/1995 Authors: Trabandt A; Gay RE; Sikhatme VP; Gay S
• Nucleotide sequence and peptide motifs of mouse uromodulin (Tamm-Horsfall protein)--the most abundant protein in mammalian urine.
  Biochim Biophys Acta Volume: 1260 Page(s): 328 - 332
  02/21/1995 Authors: Prasadan K; Bates J; Badgett A; Dell M; Sukhatme V; Yu H; Kumar S
• The zinc finger transcription factor EGR-1 impedes interleukin-1-inducible tumor growth arrest.
  Mol Cell Biol Volume: 15 Page(s): 682 - 692
  02/01/1995 Authors: Sells SF; Muthukumar S; Sukhatme VP; Crist SA; Rangnekar VM
• TRANSCRIPTIONAL REGULATION IN KIDNEY DEVELOPMENT
  Volume: 47 Page(s): 693 - 693
  02/01/1995 Authors: SUKHATME VP
• Early growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors.
  Prog Nucleic Acid Res Mol Biol Volume: 50 Page(s): 191 - 224
  01/01/1995 Authors: Gashler A; Sukhatme VP
• Growth of LLC-PK1 renal cells is mediated by EGR-1 up-regulation of G protein alpha i-2 protooncogene transcription.
  J Biol Chem Volume: 269 Page(s): 27503 - 27509
  11/04/1994 Authors: Kinane TB; Finder JD; Kawashima A; Brown D; Abbate M; Shang C; Fredericks WJ; Rauscher FJ; Sukhatme VP; Ercolani L
• The zebrafish egr1 gene encodes a highly conserved, zinc-finger transcriptional regulator.
  DNA Cell Biol Volume: 13 Page(s): 1047 - 1055
  10/01/1994 Authors: Drummond IA; Rohwer-Nutter P; Sukhatme VP
• The zebrafish egr1 gene encodes a highly conserved, zinc-finger transcriptional regulator.
  DNA Cell Biol Volume: 13 Page(s): 953 - 961
  09/01/1994 Authors: Drummond IA; Rohwer-Nutter P; Sukhatme VP
• TARGETING OF TAMM-HORSFALL PROTEIN GENE IN EMBRYONAL STEM-CELLS
  Volume: 5 Page(s): 655 - 655
  09/01/1994 Authors: BATES J; PRASADAN K; SUKHATME V; BADGETT A; KUMAR S
• REPRESSION OF THE G-ALPHA-I-2 PROTOONCOGENE IN RENAL-CELLS BY WT1
  Volume: 5 Page(s): 718 - 718
  09/01/1994 Authors: KINANE TB; FINDER J; KAWASHIMA A; SHANG C; ABBATE FM; BROWN D; HABER D; RAUSCHER F; SUKHATME V; ERCOLANI L
• NUCLEOTIDE-SEQUENCE AND PEPTIDE MOTIFS OF MOUSE TAMM-HORSFALL PROTEIN - THE MOST ABUNDANT PROTEIN IN MAMMALIAN URINE
  Volume: 5 Page(s): 668 - 668
  09/01/1994 Authors: PRASADAN K; BATES J; BADGETT A; DELL M; SUKHATME V; YU HR; KUMAR S
• Egr-1 activation of rat adrenal phenylethanolamine N-methyltransferase gene.
  J Biol Chem Volume: 269 Page(s): 20885 - 20898
  08/19/1994 Authors: Ebert SN; Balt SL; Hunter JP; Gashler A; Sukhatme V; Wong DL
• Gene therapy targeted by radiation preferentially radiosensitizes tumor cells.
  Cancer Res Volume: 54 Page(s): 4266 - 4269
  08/15/1994 Authors: Weichselbaum RR; Hallahan DE; Beckett MA; Mauceri HJ; Lee H; Sukhatme VP; Kufe DW
• Mitogenic signals control translation of the early growth response gene-1 in myogenic cells.
  Biochem Biophys Res Commun Volume: 202 Page(s): 1337 - 1346
  08/15/1994 Authors: Maass A; Groh C; Oberdorf S; Sukhatme VP; Vetter H; Neyses L
• DNA recognition by splicing variants of the Wilms' tumor suppressor, WT1.
  Mol Cell Biol Volume: 14 Page(s): 3800 - 3809
  06/01/1994 Authors: Drummond IA; Rupprecht HD; Rohwer-Nutter P; Lopez-Guisa JM; Madden SL; Rauscher FJ; Sukhatme VP
• Serum response elements mediate protein kinase C dependent transcriptional induction of early growth response gene-1 by arginine vasopressin in rat mesangial cells.
  J Cell Physiol Volume: 159 Page(s): 311 - 323
  05/01/1994 Authors: Rupprecht HD; Sukhatme VP; Rupprecht AP; Sterzel RB; Coleman DL
• Repression of the transforming growth factor-beta 1 gene by the Wilms' tumor suppressor WT1 gene product.
  Mol Endocrinol Volume: 8 Page(s): 595 - 602
  05/01/1994 Authors: Dey BR; Sukhatme VP; Roberts AB; Sporn MB; Rauscher FJ; Kim SJ
• Transcriptional repression of the insulin-like growth factor I receptor (IGF-I-R) gene by the tumor suppressor WT1 involves binding to sequences both upstream and downstream of the IGF-I-R gene transcription start site.
  J Biol Chem Volume: 269 Page(s): 12577 - 12582
  04/29/1994 Authors: Werner H; Rauscher FJ; Sukhatme VP; Drummond IA; Roberts CT; LeRoith D
• Involvement of serum response element in okadaic acid-induced EGR-1 transcription in human T-cells.
  Cancer Res Volume: 54 Page(s): 2234 - 2239
  04/15/1994 Authors: Chauhan D; Kharbanda SM; Uchiyama H; Sukhatme VP; Kufe DW; Anderson KC
• Activation of early growth response 1 gene transcription and pp90rsk during induction of monocytic differentiation.
  Cell Growth Differ Volume: 5 Page(s): 259 - 265
  03/01/1994 Authors: Kharbanda S; Saleem A; Hirano M; Emoto Y; Sukhatme V; Blenis J; Kufe D
• The Wilms' tumor suppressor gene WT1 is negatively autoregulated.
  J Biol Chem Volume: 269 Page(s): 6198 - 6206
  02/25/1994 Authors: Rupprecht HD; Drummond IA; Madden SL; Rauscher FJ; Sukhatme VP
• Bovine and rodent tamm-horsfall protein (THP) genes: cloning, structural analysis, and promoter identification.
  Gene Expr Volume: 4 Page(s): 63 - 75
  01/01/1994 Authors: Yu H; Papa F; Sukhatme VP
• Activation of the early growth response 1 gene and nuclear pp90rsk in human myeloid leukemia cells by 1-(beta-D-arabinofuranosyl)cytosine.
  Biochemistry Volume: 32 Page(s): 9137 - 9142
  09/07/1993 Authors: Kharbanda S; Saleem A; Rubin E; Sukhatme V; Blenis J; Kufe D
• PDGF-induced Egr-1 expression in rat mesangial cells is mediated through upstream serum response elements.
  Am J Physiol Volume: 265 Page(s): F351 - F360
  09/01/1993 Authors: Rupprecht HD; Sukhatme VP; Lacy J; Sterzel RB; Coleman DL
• Renal development: challenge and opportunity.
  Semin Nephrol Volume: 13 Page(s): 422 - 426
  09/01/1993 Authors: Sukhatme VP
• EGR-1, A TRANSCRIPTIONAL REGULATOR OF PHENYLETHANOLOAMINE N-METHYLTRANSFERASE GENE-EXPRESSION - SYNERGISTIC EFFECTS WITH THE GLUCOCORTICOID RECEPTOR
  Volume: 9 Page(s): S83 - S84
  09/01/1993 Authors: WONG DL; EBERT SN; HUNTER J; GASHER A; SUKHATME VP
• Induction of immediate-early genes by angiotensin II and endothelin-1 in adult rat cardiomyocytes.
  J Hypertens Volume: 11 Page(s): 927 - 934
  09/01/1993 Authors: Neyses L; Nouskas J; Luyken J; Fronhoffs S; Oberdorf S; Pfeifer U; Williams RS; Sukhatme VP; Vetter H
• A novel repression module, an extensive activation domain, and a bipartite nuclear localization signal defined in the immediate-early transcription factor Egr-1.
  Mol Cell Biol Volume: 13 Page(s): 4556 - 4571
  08/01/1993 Authors: Gashler AL; Swaminathan S; Sukhatme VP
• Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product.
  Proc Natl Acad Sci U S A Volume: 90 Page(s): 5828 - 5832
  06/15/1993 Authors: Werner H; Re GG; Drummond IA; Sukhatme VP; Rauscher FJ; Sens DA; Garvin AJ; LeRoith D; Roberts CT
• DETECTION OF EARLY GROWTH-RESPONSE GENE-1 (EGR-1) EXPRESSION IN SYNOVIAL TISSUE BY INSITU-HYBRIDIZATION
  Volume: 36 Page(s): R20 - R20
  05/01/1993 Authors: HEER AH; KEYSZER GM; SUKHATME VP; GAY S
• EXPRESSION OF THE NUCLEAR TRANSCRIPTION FACTOR EGR-1 IN LUNG FIBROBLASTS FROM AIR AND O2-EXPOSED IMMATURE RATS
  Volume: 147 Page(s): A932 - A932
  04/01/1993 Authors: KELLEHER MD; SOLWAY J; SUKHATME V; NAURECKAS ET; ZIMMERMANN A; RUBINSTEIN V; HERSHENSON MB
• TRANSCRIPTION FACTORS INCREASE DURING OXIDATIVE LUNG INJURY
  Volume: 147 Page(s): A1005 - A1005
  04/01/1993 Authors: HARRIS ZL; GIUS D; RIDGE K; SUKHATME V; SZNAJDER JI
• CELL-GROWTH IS MEDIATED BY EGR-1 ACTIVATION OF THE G-ALPHA-2 PROTOONCOGENE IN EPITHELIAL-CELLS
  Volume: 147 Page(s): A943 - A943
  04/01/1993 Authors: KINANE TB; FINDER J; SHANG C; SUKHATME V; ERCOLANI L
• Reactive oxygen intermediates target CC(A/T)6GG sequences to mediate activation of the early growth response 1 transcription factor gene by ionizing radiation.
  Proc Natl Acad Sci U S A Volume: 90 Page(s): 2419 - 2422
  03/15/1993 Authors: Datta R; Taneja N; Sukhatme VP; Qureshi SA; Weichselbaum R; Kufe DW
• EARLY GROWTH RESPONSE-1 GENE-PRODUCT IN TRABECULAR CELLS IS INDUCED BY TRANSFORMING GROWTH-FACTOR-BETA-1
  Volume: 34 Page(s): 1451 - 1451
  03/15/1993 Authors: TRIPATHI RC; LI J; TRIPATHI BJ; BORISUTH NSC; SUKHATME V
• Radiation signaling mediated by Jun activation following dissociation from a cell type-specific repressor.
  J Biol Chem Volume: 268 Page(s): 4903 - 4907
  03/05/1993 Authors: Hallahan DE; Gius D; Kuchibhotla J; Sukhatme V; Kufe DW; Weichselbaum RR
• Expression of Egr-1 in the brain of sleep deprived rats.
  Brain Res Mol Brain Res Volume: 17 Page(s): 300 - 306
  03/01/1993 Authors: Landis CA; Collins BJ; Cribbs LL; Sukhatme VP; Bergmann BM; Rechtschaffen A; Smalheiser NR
• Transcriptional regulation of the early growth response 1 gene in human myeloid leukemia cells by okadaic acid.
  Cell Growth Differ Volume: 4 Page(s): 17 - 23
  01/01/1993 Authors: Kharbanda S; Rubin E; Datta R; Hass R; Sukhatme V; Kufe D
• Human platelet-derived growth factor A chain is transcriptionally repressed by the Wilms tumor suppressor WT1.
  Proc Natl Acad Sci U S A Volume: 89 Page(s): 10984 - 10988
  11/15/1992 Authors: Gashler AL; Bonthron DT; Madden SL; Rauscher FJ; Collins T; Sukhatme VP
• Molecular biology in nephrology: an overview with emphasis on the study of renal cancer.
  Semin Nephrol Volume: 12 Page(s): 495 - 505
  11/01/1992 Authors: Cohen HT; Sukhatme VP
• Lipopolysaccharide induces Egr-1 mRNA and protein in murine peritoneal macrophages.
  J Immunol Volume: 149 Page(s): 3045 - 3051
  11/01/1992 Authors: Coleman DL; Bartiss AH; Sukhatme VP; Liu J; Rupprecht HD
• Ionizing radiation activates transcription of the EGR1 gene via CArG elements.
  Proc Natl Acad Sci U S A Volume: 89 Page(s): 10149 - 10153
  11/01/1992 Authors: Datta R; Rubin E; Sukhatme V; Qureshi S; Hallahan D; Weichselbaum RR; Kufe DW
• Evidence that activation of the Egr-1 promoter by v-Raf involves serum response elements.
  Oncogene Volume: 7 Page(s): 2065 - 2068
  10/01/1992 Authors: Rim M; Qureshi SA; Gius D; Nho J; Sukhatme VP; Foster DA
• Effect of vasoactive agents on induction of Egr-1 in rat mesangial cells: correlation with mitogenicity.
  Am J Physiol Volume: 263 Page(s): F623 - F636
  10/01/1992 Authors: Rupprecht HD; Dann P; Sukhatme VP; Sterzel RB; Coleman DL
• Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1.
  Science Volume: 257 Page(s): 674 - 678
  07/31/1992 Authors: Drummond IA; Madden SL; Rohwer-Nutter P; Bell GI; Sukhatme VP; Rauscher FJ
• v-Fps-responsiveness in the Egr-1 promoter is mediated by serum response elements.
  Nucleic Acids Res Volume: 20 Page(s): 2355 - 2359
  05/11/1992 Authors: Alexandropoulos K; Qureshi SA; Rim M; Sukhatme VP; Foster DA
• Expression of collagenase and potential transcriptional factors c-fos and egr-1 in periodontal gingival fibroblasts.
  J Oral Pathol Med Volume: 21 Page(s): 232 - 240
  05/01/1992 Authors: Trabandt A; Gay RE; Sukhatme VP; Gay S
• The Egr transcription factor family: from signal transduction to kidney differentiation.
  Kidney Int Volume: 41 Page(s): 550 - 553
  03/01/1992 Authors: Sukhatme VP
• ROLE OF PROTEIN-KINASE-C IN THE INDUCTION OF EGR-1 MESSENGER-RNA IN RAT MESANGIAL CELLS BY PDGF AND AVP
  Volume: 41 Page(s): 698 - 698
  03/01/1992 Authors: RUPPRECHT HD; SUKHATME VP; STERZEL RB; COLEMAN DL
• GP-2/THP gene family encodes self-binding glycosylphosphatidylinositol-anchored proteins in apical secretory compartments of pancreas and kidney.
  Proc Natl Acad Sci U S A Volume: 89 Page(s): 1189 - 1193
  02/15/1992 Authors: Fukuoka S; Freedman SD; Yu H; Sukhatme VP; Scheele GA
• Models of insulin action on metabolic and growth response genes.
  Mol Cell Biochem Volume: 109 Page(s): 99 - 105
  02/12/1992 Authors: Alexander-Bridges M; Buggs C; Giere L; Denaro M; Kahn B; White M; Sukhatme V; Nasrin N
• Regulation of the Egr-1 gene by tumor necrosis factor and interferons in primary human fibroblasts.
  J Biol Chem Volume: 267 Page(s): 1345 - 1349
  01/15/1992 Authors: Cao XM; Guy GR; Sukhatme VP; Tan YH
• Sustained induction of egr-1 by v-src correlates with a lack of fos-mediated repression of the egr-1 promoter.
  Oncogene Volume: 7 Page(s): 121 - 125
  01/01/1992 Authors: Qureshi SA; Rim MH; Alexandropoulos K; Berg K; Sukhatme VP; Foster DA
• Gene therapy targeted by ionizing radiation.
  Int J Radiat Oncol Biol Phys Volume: 24 Page(s): 565 - 567
  01/01/1992 Authors: Weichselbaum RR; Hallahan DE; Sukhatme VP; Kufe DW
• Spontaneous expression of immediately-early response genes c-fos and egr-1 in collagenase-producing rheumatoid synovial fibroblasts.
  Rheumatol Int Volume: 12 Page(s): 53 - 59
  01/01/1992 Authors: Trabandt A; Aicher WK; Gay RE; Sukhatme VP; Fassbender HG; Gay S
• Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus.
  Oncogene Volume: 6 Page(s): 2339 - 2348
  12/01/1991 Authors: Morris JF; Madden SL; Tournay OE; Cook DM; Sukhatme VP; Rauscher FJ
• An inhibitory mutant of c-Raf-1 blocks v-Src-induced activation of the Egr-1 promoter.
  J Biol Chem Volume: 266 Page(s): 20594 - 20597
  11/05/1991 Authors: Qureshi SA; Rim M; Bruder J; Kolch W; Rapp U; Sukhatme VP; Foster DA
• Transcriptional repression mediated by the WT1 Wilms tumor gene product.
  Science Volume: 253 Page(s): 1550 - 1553
  09/27/1991 Authors: Madden SL; Cook DM; Morris JF; Gashler A; Sukhatme VP; Rauscher FJ
• Differential effects of transforming growth factor-beta 1 and phorbol myristate acetate on cardiac fibroblasts. Regulation of fibrillar collagen mRNAs and expression of early transcription factors.
  Circ Res Volume: 69 Page(s): 483 - 490
  08/01/1991 Authors: Eghbali M; Tomek R; Sukhatme VP; Woods C; Bhambi B
• Expression of the early growth response 1 and 2 zinc finger genes during induction of monocytic differentiation.
  J Clin Invest Volume: 88 Page(s): 571 - 577
  08/01/1991 Authors: Kharbanda S; Nakamura T; Stone R; Hass R; Bernstein S; Datta R; Sukhatme VP; Kufe D
• Regulation of Egr-1 (Zfp-6) and c-fos expression in differentiating embryonal carcinoma cells.
  Oncogene Volume: 6 Page(s): 1367 - 1376
  08/01/1991 Authors: Darland T; Samuels M; Edwards SA; Sukhatme VP; Adamson ED
• Egr-1, a serum-inducible zinc finger protein, regulates transcription of the rat cardiac alpha-myosin heavy chain gene.
  J Biol Chem Volume: 266 Page(s): 12813 - 12816
  07/15/1991 Authors: Gupta MP; Gupta M; Zak R; Sukhatme VP
• v-Src activates mitogen-responsive transcription factor Egr-1 via serum response elements.
  J Biol Chem Volume: 266 Page(s): 10802 - 10806
  06/15/1991 Authors: Qureshi SA; Cao XM; Sukhatme VP; Foster DA
• The Egr family of nuclear signal transducers.
  Am J Kidney Dis Volume: 17 Page(s): 615 - 618
  06/01/1991 Authors: Sukhatme VP
• Posttranscriptional regulation of the zinc finger-encoding EGR-1 gene by granulocyte-macrophage colony-stimulating factor in human U-937 monocytic leukemia cells: involvement of a pertussis toxin-sensitive G protein.
  Cell Growth Differ Volume: 2 Page(s): 273 - 278
  06/01/1991 Authors: Bernstein SH; Kharbanda SM; Sherman ML; Sukhatme VP; Kufe DW
• EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors.
  Oncogene Volume: 6 Page(s): 917 - 928
  06/01/1991 Authors: Patwardhan S; Gashler A; Siegel MG; Chang LC; Joseph LJ; Shows TB; Le Beau MM; Sukhatme VP
• Biological consequences of gene regulation after ionizing radiation exposure.
  J Natl Cancer Inst Volume: 83 Page(s): 480 - 484
  04/03/1991 Authors: Weichselbaum RR; Hallahan DE; Sukhatme V; Dritschilo A; Sherman ML; Kufe DW
• Granulocyte-macrophage colony-stimulating factor induces transcriptional activation of Egr-1 in murine peritoneal macrophages.
  J Biol Chem Volume: 266 Page(s): 5929 - 5933
  03/25/1991 Authors: Liu JW; Lacy J; Sukhatme VP; Coleman DL
• Protein kinase C mediates x-ray inducibility of nuclear signal transducers EGR1 and JUN.
  Proc Natl Acad Sci U S A Volume: 88 Page(s): 2156 - 2160
  03/15/1991 Authors: Hallahan DE; Sukhatme VP; Sherman ML; Virudachalam S; Kufe D; Weichselbaum RR
• GM-CSF INCREASES EGR-1 PROMOTER ACTIVITY IN MURINE PERITONEAL-MACROPHAGES
  Volume: 5 Page(s): A964 - A964
  03/15/1991 Authors: RUPPRECHT A; SUKHATME V; CAO X; COLEMAN D
• REGULATION OF EGR-1 EXPRESSION DURING ANTIGEN RECEPTOR-MEDIATED ACTIVATION OF B LYMPHOCYTES
  Volume: 5 Page(s): A611 - A611
  03/11/1991 Authors: MCMAHON SB; SUKHATME VP; MONROE JG
• Phorbol ester-mediated inhibition of growth and regulation of proto-oncogene expression in the human T cell leukemia line JURKAT.
  Oncogene Volume: 6 Page(s): 455 - 460
  03/01/1991 Authors: Makover D; Cuddy M; Yum S; Bradley K; Alpers J; Sukhatme V; Reed JC
• Localization of the protein product of the immediate early growth response gene, Egr-1, in the kidney after ischemia and reperfusion.
  Cell Regul Volume: 2 Page(s): 251 - 260
  03/01/1991 Authors: Bonventre JV; Sukhatme VP; Bamberger M; Ouellette AJ; Brown D
• Signaling through surface IgM in tolerance-susceptible immature murine B lymphocytes. Developmentally regulated differences in transmembrane signaling in splenic B cells from adult and neonatal mice.
  J Immunol Volume: 146 Page(s): 1446 - 1454
  03/01/1991 Authors: Yellen AJ; Glenn W; Sukhatme VP; Cao XM; Monroe JG
• Early transcriptional events in cell growth: the Egr family.
  J Am Soc Nephrol Volume: 1 Page(s): 859 - 866
  12/01/1990 Authors: Sukhatme VP
• Expression of the collagenolytic and Ras-induced cysteine proteinase cathepsin L and proliferation-associated oncogenes in synovial cells of MRL/I mice and patients with rheumatoid arthritis.
  Matrix Volume: 10 Page(s): 349 - 361
  12/01/1990 Authors: Trabandt A; Aicher WK; Gay RE; Sukhatme VP; Nilson-Hamilton M; Hamilton RT; McGhee JR; Fassbender HG; Gay S
• Egr-1 expression in surface Ig-mediated B cell activation. Kinetics and association with protein kinase C activation.
  J Immunol Volume: 145 Page(s): 3647 - 3653
  12/01/1990 Authors: Seyfert VL; McMahon S; Glenn W; Cao XM; Sukhatme VP; Monroe JG
• Methylation of an immediate-early inducible gene as a mechanism for B cell tolerance induction.
  Science Volume: 250 Page(s): 797 - 800
  11/09/1990 Authors: Seyfert VL; McMahon SB; Glenn WD; Yellen AJ; Sukhatme VP; Cao XM; Monroe JG
• A refined linkage map for DNA markers around the pericentromeric region of chromosome 10.
  Genomics Volume: 8 Page(s): 461 - 468
  11/01/1990 Authors: Wu JS; Myers S; Carson N; Kidd JR; Anderson L; Castiglione CM; Hoyle LS; Lichter JB; Sukhatme VP; Simpson NE
• Alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. fos/jun expression is associated with sarcomere assembly; Egr-1 induction is primarily an alpha 1-mediated response.
  J Biol Chem Volume: 265 Page(s): 13809 - 13817
  08/15/1990 Authors: Iwaki K; Sukhatme VP; Shubeita HE; Chien KR
• Transcriptional activation and repression by Fos are independent functions: the C terminus represses immediate-early gene expression via CArG elements.
  Mol Cell Biol Volume: 10 Page(s): 4243 - 4255
  08/01/1990 Authors: Gius D; Cao XM; Rauscher FJ; Cohen DR; Curran T; Sukhatme VP
• cDNA sequence of the human cellular early growth response gene Egr-1.
  Nucleic Acids Res Volume: 18 Page(s): 4283
  07/25/1990 Authors: Suggs SV; Katzowitz JL; Tsai-Morris C; Sukhatme VP
• The serum and TPA responsive promoter and intron-exon structure of EGR2, a human early growth response gene encoding a zinc finger protein.
  Nucleic Acids Res Volume: 18 Page(s): 2749 - 2757
  05/11/1990 Authors: Rangnekar VM; Aplin AC; Sukhatme VP
• Identification and characterization of the Egr-1 gene product, a DNA-binding zinc finger protein induced by differentiation and growth signals.
  Mol Cell Biol Volume: 10 Page(s): 1931 - 1939
  05/01/1990 Authors: Cao XM; Koski RA; Gashler A; McKiernan M; Morris CF; Gaffney R; Hay RV; Sukhatme VP
• LOCALIZATION OF THE EGR-1 PROTEIN PRODUCT TO THE DISTAL NEPHRON AFTER RENAL ISCHEMIA AND REPERFUSION
  Volume: 38 Page(s): A442 - A442
  04/01/1990 Authors: BONVENTRE JV; OUELLETTE AJ; SUKHATME VP; BROWN D
• Expression of two "immediate early" genes, Egr-1 and c-fos, in response to renal ischemia and during compensatory renal hypertrophy in mice.
  J Clin Invest Volume: 85 Page(s): 766 - 771
  03/01/1990 Authors: Ouellette AJ; Malt RA; Sukhatme VP; Bonventre JV
• Developmental expression of the putative transcription factor Egr-1 suggests that Egr-1 and c-fos are coregulated in some tissues.
  Development Volume: 108 Page(s): 281 - 287
  02/01/1990 Authors: McMahon AP; Champion JE; McMahon JA; Sukhatme VP
• Conditioned medium from ras oncogene-transformed NIH 3T3 cells induces bone resorption in vitro.
  J Bone Miner Res Volume: 5 Page(s): 159 - 164
  02/01/1990 Authors: Krieger NS; Sukhatme VP; Bushinsky DA
• Differential expression of a zinc finger-encoding gene in response to positive versus negative signaling through receptor immunoglobulin in murine B lymphocytes.
  Mol Cell Biol Volume: 9 Page(s): 2083 - 2088
  05/01/1989 Authors: Seyfert VL; Sukhatme VP; Monroe JG
• Multiple intracellular pathways induce expression of a zinc-finger encoding gene (EGR1): relationship to activation of the Na/H exchanger.
  J Cell Physiol Volume: 139 Page(s): 262 - 268
  05/01/1989 Authors: Jamieson GA; Mayforth RD; Villereal ML; Sukhatme VP
• Synthesis and processing of cathepsin L, an elastase, by human alveolar macrophages.
  Biochem J Volume: 257 Page(s): 493 - 498
  01/15/1989 Authors: Reilly JJ; Mason RW; Chen P; Joseph LJ; Sukhatme VP; Yee R; Chapman HA
• CATHEPSIN-L (CTSL) IS LOCATED IN THE CHROMOSOME-9Q21-Q22 REGION - A RELATED SEQUENCE IS LOCATED ON CHROMOSOME-10
  Volume: 51 Page(s): 996 - 996
  01/01/1989 Authors: FAN YS; BYERS MG; EDDY RL; JOSEPH L; SUKHATME V; CHAN SJ; SHOWS TB
• INDUCTION OF C-FOS AND THE EARLY GROWTH-RESPONSE GENE EGR-1 IN MICE AFTER RENAL ISCHEMIA
  Volume: 35 Page(s): 415 - 415
  01/01/1989 Authors: OUELLETTE AJ; MALT RA; SUKHATME VP; BONVENTRE JV
• A REFINED GENETIC-LINKAGE MAP FOR THE PERICENTRIC REGION OF CHROMOSOME-10 BASED ON NON-CEPH FAMILIES
  Volume: 51 Page(s): 1111 - 1111
  01/01/1989 Authors: WU J; MYERS S; GOODFELLOW PJ; CASTIGLIONE CM; KIDD JR; CARSON NL; ANDERSON L; SPURR NK; SUKHATME V; SIMPSON NE
• VASOPRESSIN INCREASES THE EXPRESSION OF THE EARLY GROWTH-RESPONSE GENE, EGR-1, IN CULTURED MESANGIAL CELLS
  Volume: 35 Page(s): 169 - 169
  01/01/1989 Authors: BONVENTRE JV; SULLIVAN S; SUKHATME VP; OUELLETTE AJ
• ASSIGNMENT OF HUMAN MINERALOCORTICOID RECEPTOR (MLR) TO HUMAN CHROMOSOME-4Q31.2
  Volume: 51 Page(s): 996 - 996
  01/01/1989 Authors: FAN YS; EDDY RL; BYERS MG; HALEY LL; HENRY WM; SHOWS TB
• COLLAGENASE TYPE-IV (CLG4) IS MAPPED TO HUMAN CHROMOSOME-16Q21
  Volume: 51 Page(s): 996 - 996
  01/01/1989 Authors: FAN YS; EDDY RL; HUHTALA P; BYERS MG; HALEY LL; HENRY WM; TRYGGVASON K; SHOWS TB
• Nucleotide sequence of a cDNA encoding TIS11, a message induced in Swiss 3T3 cells by the tumor promoter tetradecanoyl phorbol acetate.
  Oncogene Volume: 4 Page(s): 119 - 120
  01/01/1989 Authors: Varnum BC; Lim RW; Sukhatme VP; Herschman HR
• A HindIII polymorphism identified by the human early growth response gene 2 (EGR2) on chromosome 10.
  Nucleic Acids Res Volume: 16 Page(s): 11855
  12/23/1988 Authors: Wu J; Joseph L; Sukhatme VP; Kidd KK
• Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with "zinc-binding finger" structure.
  Proc Natl Acad Sci U S A Volume: 85 Page(s): 7164 - 7168
  10/01/1988 Authors: Joseph LJ; Le Beau MM; Jamieson GA; Acharya S; Shows TB; Rowley JD; Sukhatme VP
• 5' flanking sequence and genomic structure of Egr-1, a murine mitogen inducible zinc finger encoding gene.
  Nucleic Acids Res Volume: 16 Page(s): 8835 - 8846
  09/26/1988 Authors: Tsai-Morris CH; Cao XM; Sukhatme VP
• Isolation and sequence of a cDNA clone encoding the 31-kDa subunit of bovine kidney vacuolar H+-ATPase.
  Proc Natl Acad Sci U S A Volume: 85 Page(s): 3004 - 3008
  05/01/1988 Authors: Hirsch S; Strauss A; Masood K; Lee S; Sukhatme V; Gluck S
• Complete nucleotide and deduced amino acid sequences of human and murine preprocathepsin L. An abundant transcript induced by transformation of fibroblasts.
  J Clin Invest Volume: 81 Page(s): 1621 - 1629
  05/01/1988 Authors: Joseph LJ; Chang LC; Stamenkovich D; Sukhatme VP
• A zinc finger-encoding gene coregulated with c-fos during growth and differentiation, and after cellular depolarization.
  Cell Volume: 53 Page(s): 37 - 43
  04/08/1988 Authors: Sukhatme VP; Cao XM; Chang LC; Tsai-Morris CH; Stamenkovich D; Ferreira PC; Cohen DR; Edwards SA; Shows TB; Curran T
• REGULATION OF THE SYNTHESIS AND PROCESSING OF CATHEPSIN-L
  Volume: 2 Page(s): A1822 - A1822
  03/25/1988 Authors: REILLY J; CHEN P; JOSEPH L; SUKHATME V; CHAPMAN H
• CONDITIONED MEDIA FROM RAS ONCOGENE TRANSFORMED NIH3T3 CELLS INDUCES BONE-RESORPTION
  Volume: 33 Page(s): 349 - 349
  01/01/1988 Authors: SUKHATME VP; WRIGHT LL; BUSHINSKY DA
• MOLECULAR-CLONING OF A NOVEL EARLY GROWTH-RESPONSE GENE RAPIDLY INDUCED BY KIDNEY EPITHELIAL-CELL FIBROBLAST AND LYMPHOCYTE MITOGENS
  Volume: 33 Page(s): 175 - 175
  01/01/1988 Authors: TSAIMORRIS C; KARTHA S; TOBACK FG; TAUB R; HOOVER R; SUKHATME V
• ADP activates protooncogene expression in renal epithelial cells.
  Am J Physiol Volume: 252 Page(s): F1175 - F1179
  06/01/1987 Authors: Kartha S; Sukhatme VP; Toback FG
• The major ras induced protein in NIH3T3 cells is cathepsin L.
  Nucleic Acids Res Volume: 15 Page(s): 3186
  04/10/1987 Authors: Joseph L; Lapid S; Sukhatme V
• Molecular analysis of the CD8 gene in multiple sclerosis.
  J Neuroimmunol Volume: 14 Page(s): 183 - 187
  03/01/1987 Authors: Reder AT; Antel JP; Singh S; Stoklosa C; Sukhatme V
• A novel early growth response gene rapidly induced by fibroblast, epithelial cell and lymphocyte mitogens.
  Oncogene Res Volume: 1 Page(s): 343 - 355
  01/01/1987 Authors: Sukhatme VP; Kartha S; Toback FG; Taub R; Hoover RG; Tsai-Morris CH
• Structure of Leu-2/T8 as deduced from the sequence of a cDNA clone.
  Behring Inst Mitt Page(s): 48 - 55
  08/01/1985 Authors: Parnes JR; Sizer KC; Sukhatme VP; Hunkapiller T
• The T cell differentiation antigen Leu-2/T8 is homologous to immunoglobulin and T cell receptor variable regions.
  Cell Volume: 40 Page(s): 591 - 597
  03/01/1985 Authors: Sukhatme VP; Sizer KC; Vollmer AC; Hunkapiller T; Parnes JR
• Gene for the human T cell differentiation antigen Leu-2/T8 is closely linked to the kappa light chain locus on chromosome 2.
  J Exp Med Volume: 161 Page(s): 429 - 434
  02/01/1985 Authors: Sukhatme VP; Vollmer AC; Erikson J; Isobe M; Croce C; Parnes JR
• SEQUENCE AND EXPRESSION OF LYT-2
  Volume: 44 Page(s): 1177 - 1177
  01/01/1985 Authors: ZAMOYSKA R; VOLLMER AC; SUKHATME VP; SIZER KC; PARNES JR
• Isolation of the gene encoding the human T-lymphocyte differentiation antigen Leu-2 (T8) by gene transfer and cDNA subtraction.
  Proc Natl Acad Sci U S A Volume: 81 Page(s): 7688 - 7692
  12/01/1984 Authors: Kavathas P; Sukhatme VP; Herzenberg LA; Parnes JR
• REGULATION OF PROTEIN-SYNTHESIS BY HEME IN RABBIT RETICULOCYTES - INVIVO PHOSPHORYLATION OF MET-TRANSFER-RNAF BINDING FACTOR IN HEME DEFICIENCY
  Volume: 48 Page(s): 999 - 999
  01/01/1976 Authors: SUKHATME V; RANU RS; LONDON IM