Publications

• Sonic hedgehog medulloblastomas are dependent on Netrin-1 for survival.
  Nat Commun Volume: 16 Page(s): 5137
  06/03/2025 Authors: Talbot J; Fombonne J; Torrejon J; Babcock BR; McSwain LF; Rama N; Lospinoso Severini L; Bonerandi E; Marsaud V; Bernardi F
• Reply to: Challenges in Assessing Response in Clinical Trials for Neurofibromatosis Type 1 Plexiform Neurofibromas.
  J Clin Oncol Volume: 43 Page(s): 1844 - 1846
  05/20/2025 Authors: Moertel CL; Hirbe AC; Klesse LJ; Nghiemphu PL; Babovic-Vuksanovic D; Gershon TR
• ReNeu: A Pivotal Phase 2b Trial of Mirdametinib in Children and Adults With Neurofibromatosis Type 1 (NF1)-Associated Symptomatic Plexiform Neurofibroma (PN) (S29.003).
  Neurology Volume: 104 Page(s): 2232
  04/08/2025 Authors: Shuhaiber H; Moertel C; Hirbe A; Viskochil D; Sidhu A; Bielamowicz K; Weber M; Lokku A; Smith LM; Weintraub L
• ReNeu: A Pivotal, Phase IIb Trial of Mirdametinib in Adults and Children With Symptomatic Neurofibromatosis Type 1-Associated Plexiform Neurofibroma.
  J Clin Oncol Volume: 43 Page(s): 716 - 729
  02/20/2025 Authors: Moertel CL; Hirbe AC; Shuhaiber HH; Bielamowicz K; Sidhu A; Viskochil D; Weber MD; Lokku A; Smith LM; Foreman NK
• Suppressing recurrence in Sonic Hedgehog subgroup medulloblastoma using the OLIG2 inhibitor CT-179.
  Nat Commun Volume: 16 Page(s): 1091
  02/04/2025 Authors: Li Y; Lim C; Dismuke T; Malawsky DS; Oasa S; Bruce ZC; Offenhuser C; Baumgartner U; D'Souza RCJ; Edwards SL
• Selective Posterior Cerebral Artery Wada Better Predicts Good Memory and Naming Outcomes Following Selective Stereotactic Thermal Ablation for Medial Temporal Lobe Epilepsy Than Internal Carotid Artery Wada.
  medRxiv
  03/26/2024 Authors: Drane DL; Acerbo E; Rogers A; Pedersen NP; Williamson A; Stern MA; Dickey AS; Howard BM; Bearden DJ; Okada N
• Chronic AMPK inactivation slows SHH medulloblastoma progression by inhibiting mTORC1 signaling and depleting tumor stem cells.
  iScience Volume: 26 Page(s): 108443
  12/15/2023 Authors: Malawsky DS; Dismuke T; Liu H; Castellino E; Brenman J; Dasgupta B; Tikunov A; Gershon TR
• Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX.
  Cancer Res Volume: 83 Page(s): 3442 - 3461
  10/13/2023 Authors: Singh R; Yu S; Osman M; Inde Z; Fraser C; Cleveland AH; Almanzar N; Lim CB; Joshi GN; Spetz J
• Preventing recurrence in Sonic Hedgehog Subgroup Medulloblastoma using the OLIG2 inhibitor CT-179.
  Res Sq
  06/09/2023 Authors: Li Y; Lim C; Dismuke T; Malawsky DS; Oasa S; Bruce ZC; Offenhuser C; Baumgartner U; D'Souza RCJ; Edwards SL
• IGFBP2 promotes proliferation and cell migration through STAT3 signaling in Sonic hedgehog medulloblastoma.
  Acta Neuropathol Commun Volume: 11 Page(s): 62
  04/08/2023 Authors: Kunhiraman H; McSwain L; Shahab SW; Gershon TR; MacDonald TJ; Kenney AM
• PRC2 disruption in cerebellar progenitors produces cerebellar hypoplasia and aberrant myoid differentiation without blocking medulloblastoma growth.
  Acta Neuropathol Commun Volume: 11 Page(s): 8
  01/12/2023 Authors: Cleveland AH; Malawsky D; Churiwal M; Rodriguez C; Reed F; Schniederjan M; Velazquez Vega JE; Davis I; Gershon TR
• Automated Immunofluorescence Staining for Analysis of DNA Damage and Apoptosis in Brain Sections.
  Volume: 2583 Page(s): 55 - 61
  01/01/2023 Authors: De la Cruz G; Nikolaishvili-Feinberg N; Gershon TR
• Processing Neonatal Mouse Brains for Immunohistochemical Analysis: As Required for Including Spindle Orientation Analysis and Analysis of DNA Damage and Apoptosis.
  Volume: 2583 Page(s): 49 - 54
  01/01/2023 Authors: De la Cruz G; Nikolaishvili-Feinberg N; Williams SE; Gershon TR
• scRNA-seq for Microcephaly Research [IV]: Dirichlet Regression for Single-Cell Population Differences.
  Volume: 2583 Page(s): 123 - 125
  01/01/2023 Authors: Malawsky D; Gershon TR
• ASTROCYTIC SOX2(+) CELLS RELAY IN NON-CANONICAL GLI SIGNALING TO FACILITATE MEDULLOBLASTOMA RELAPSE.
  Volume: 24 Page(s): 36 - 37
  11/01/2022 Authors: Swiderska-Syn M; Mir-Pedrol J; Oles A; Babcock B; Martin V; Krieg C; Gershon T; McCrea H; Rodriguez-Blanco J
• DISRUPTION OF THE SERINE-PRODUCING PATHWAYS SLOWS PROGRESSION OF THE SONIC HEDGEHOG-DRIVEN MEDULLOBLASTOMA
  Volume: 24 Page(s): 261 - 261
  11/01/2022 Authors: Tikunov A; Bates D; Macdonald J; Gershon T
• Mechanisms of CD40-dependent cDC1 licensing beyond costimulation.
  Nat Immunol Volume: 23 Page(s): 1536 - 1550
  11/01/2022 Authors: Wu R; Ohara RA; Jo S; Liu T-T; Ferris ST; Ou F; Kim S; Theisen DJ; Anderson DA; Wong BW
• OLIG2 Is a Determinant for the Relapse of MYC-Amplified Medulloblastoma.
  Clin Cancer Res Volume: 28 Page(s): 4278 - 4291
  10/03/2022 Authors: Xu Z; Murad N; Malawsky D; Tao R; Rivero-Hinojosa S; Holdhof D; Schller U; Zhang P; Lazarski C; Rood BR
• Spatiotemporal analysis of induced neural stem cell therapy to overcome advanced glioblastoma recurrence.
  Mol Ther Oncolytics Volume: 26 Page(s): 49 - 62
  09/15/2022 Authors: Satterlee AB; Dunn DE; Valdivia A; Malawsky D; Buckley A; Gershon T; Floyd S; Hingtgen S
• Noncanonical activation of GLI signaling in SOX2+ cells drives medulloblastoma relapse.
  Sci Adv Volume: 8 Page(s): eabj9138
  07/22/2022 Authors: Swiderska-Syn M; Mir-Pedrol J; Oles A; Schleuger O; Salvador AD; Greiner SM; Seward C; Yang F; Babcock BR; Shen C
• EFFECTIVE CAR-T CELL MEDULLOBLASTOMA THERAPY IN AN IMMUNOCOMPETENT MOUSE MODEL
  Volume: 24 Page(s): 86 - 86
  06/01/2022 Authors: Tsahouridis R; Lim C; Sokolsky M; Dotti G; Gershon T
• POX NPS MEDIATED DELIVERY OF (TLR7/8) AGONIST RESIQUIMOD IMPROVES TREATMENT OUTCOMES IN SHH MEDULLOBLASTOMA BY TARGETING TUMOR ASSOCIATED MACROPHAGES
  Volume: 24 Page(s): 119 - 119
  06/01/2022 Authors: Hwang D; Alicea CDM; Lim C; Park C; Gershon T; Sokolsky-Papkov M
• Author Correction: scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy.
  Nat Commun Volume: 13 Page(s): 3048
  05/26/2022 Authors: Ocasio JK; Babcock B; Malawsky D; Weir SJ; Loo L; Simon JM; Zylka MJ; Hwang D; Dismuke T; Sokolsky M
• Neoplastic and immune single-cell transcriptomics define subgroup-specific intra-tumoral heterogeneity of childhood medulloblastoma.
  Neuro Oncol Volume: 24 Page(s): 273 - 286
  02/01/2022 Authors: Riemondy KA; Venkataraman S; Willard N; Nellan A; Sanford B; Griesinger AM; Amani V; Mitra S; Hankinson TC; Handler MH
• Enhancing CDK4/6 inhibitor therapy for medulloblastoma using nanoparticle delivery and scRNA-seq-guided combination with sapanisertib.
  Sci Adv Volume: 8 Page(s): eabl5838
  01/28/2022 Authors: Lim C; Dismuke T; Malawsky D; Ramsey JD; Hwang D; Godfrey VL; Kabanov AV; Gershon TR; Sokolsky-Papkov M
• Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration.
  Cell Death Dis Volume: 12 Page(s): 1133
  12/06/2021 Authors: Cleveland AH; Romero-Morales A; Azcona LA; Herrero M; Nikolova VD; Moy S; Elroy-Stein O; Gama V; Gershon TR
• IMMUNOMODULATION WITH RESIQUIMOD REPOLARIZES THE IMMUNE MICROENVIRONMENT TO INHIBIT MEDULLOBLASTOMA PROGRESSION
  Volume: 23 Page(s): 103 - 103
  11/01/2021 Authors: Park C; Del Mar C; Thang M; Dismuke T; Hwang D; Lim C; Mirlekar B; Donson A; Vibhakar R; Sokolsky M
• A fatal Case of Acute Fulminant Cerebral Edema in Pediatric COVID-19 Infection
  Volume: 90 Page(s): S111 - S112
  09/01/2021 Authors: Ninan S; Thompson P; Gershon T; Ford N; Mills W; Jewells V; Thorne L; Bouldin T; Miller M; Wu E
• DRUG RESISTANCE IN MEDULLOBLASTOMA ADDRESSED WITH OLIG2 INHIBITOR, CT-179
  Volume: 23 Page(s): 51 - 51
  06/01/2021 Authors: Dismuke T; Lim C; Gershon T
• NEOPLASTIC AND IMMUNE SINGLE CELL TRANSCRIPTOMICS DEFINE SUBGROUP-SPECIFIC INTRA-TUMORAL HETEROGENEITY OF CHILDHOOD MEDULLOBLASTOMA
  Volume: 23 Page(s): 11 - 11
  06/01/2021 Authors: Donson A; Riemondy K; Venkataraman S; Willard N; Nellan A; Sanford B; Griesinger A; Amani V; Mitra S; Hankinson T
• IMMUNOTHERAPY WITH RESIQUIMOD REPOLARIZES TUMOR-ASSOCIATED MYELOID CELLS AND IMPROVES EVENT-FREE SURVIVAL IN A TRANSGENIC MOUSE MODEL OF SONIC-HEDGEHOG (SHH) MEDULLOBLASTOMA
  Volume: 23 Page(s): 27 - 28
  06/01/2021 Authors: Park C; Thang M; Hwang D; Lim C; Dismuke T; Sokolsky M; Vibhakar R; Donson A; Gershon T
• PRC2 COMPLEX ENFORCES NEURONAL LINEAGE AND SUPPRESSES TUMOR GROWTH IN SHH MEDULLOBLASTOMA
  Volume: 23 Page(s): 8 - 9
  06/01/2021 Authors: Cleveland A; Malawsky D; Churiwal M; Gershon T
• Cryptic developmental events determine medulloblastoma radiosensitivity and cellular heterogeneity without altering transcriptomic profile.
  Commun Biol Volume: 4 Page(s): 616
  05/21/2021 Authors: Malawsky DS; Weir SJ; Ocasio JK; Babcock B; Dismuke T; Cleveland AH; Donson AM; Vibhakar R; Wilhelmsen K; Gershon TR
• Antiapoptotic Bcl-2 family proteins BCL-xL and MCL-1 integrate neural progenitor survival and proliferation during postnatal cerebellar neurogenesis.
  Cell Death Differ Volume: 28 Page(s): 1579 - 1592
  05/01/2021 Authors: Veleta KA; Cleveland AH; Babcock BR; He Y-W; Hwang D; Sokolsky-Papkov M; Gershon TR
• Poly(2-oxazoline) nanoparticle delivery enhances the therapeutic potential of vismodegib for medulloblastoma by improving CNS pharmacokinetics and reducing systemic toxicity.
  Nanomedicine Volume: 32 Page(s): 102345
  02/01/2021 Authors: Hwang D; Dismuke T; Tikunov A; Rosen EP; Kagel JR; Ramsey JD; Lim C; Zamboni W; Kabanov AV; Gershon TR
• Fatal Pediatric COVID-19 Case With Seizures and Fulminant Cerebral Edema.
  Child Neurol Open Volume: 8 Page(s): 2329048X211022532
  01/01/2021 Authors: Ninan S; Thompson P; Gershon T; Ford N; Mills W; Jewells V; Thorne L; Saunders K; Bouldin T; Smedberg JR
• ADAPTING PALBOCICLIB FOR MEDULLOBLASTOMA THERAPY BY IMPROVING DRUG DELIVERY AND ADDRESSING RESISTANCE
  Volume: 22 Page(s): 412 - 412
  12/01/2020 Authors: Dismuke T; Gershon T
• CHARTING NEOPLASTIC AND IMMUNE CELL HETEROGENEITY IN HUMAN AND GEM MODELS OF MEDULLOBLASTOMA USING SCRNASEQ
  Volume: 22 Page(s): 406 - 406
  12/01/2020 Authors: Donson A; Riemondy K; Venkataraman S; Gilani A; Sanford B; Griesinger A; Amani V; Hankinson T; Handler M; Hesselberth J
• SONIC HEDGEHOG SIGNALING PRIMES CEREBELLAR GRANULE NEURON PROGENITORS, THE CELL OF ORIGIN FOR MEDULLOBLASTOMA, FOR APOPTOSIS BY INDUCING PRO APOPTOTIC BIM
  Volume: 22 Page(s): 400 - 400
  12/01/2020 Authors: Cleveland A; Gershon T
• Content and Performance of the MiniMUGA Genotyping Array: A New Tool To Improve Rigor and Reproducibility in Mouse Research.
  Genetics Volume: 216 Page(s): 905 - 930
  12/01/2020 Authors: Sigmon JS; Blanchard MW; Baric RS; Bell TA; Brennan J; Brockmann GA; Burks AW; Calabrese JM; Caron KM; Cheney RE
• Single-Cell RNA Sequencing of Childhood Medulloblastoma
  Volume: 22 Page(s): S68 - S68
  11/01/2020 Authors: Willard N; Riemondy K; Donson A; Venkataraman S; Sanford B; Sill M; Griesinger A; Amani V; Hankinson T; Handler M
• Treatment of Trametinib-Associated Folliculitis Eruption With Fluconazole.
  JAMA Dermatol Volume: 156 Page(s): 706 - 708
  06/01/2020 Authors: Steele C; Gershon T; Burkhart C; Googe P
• Projected t-SNE for batch correction.
  Bioinformatics Volume: 36 Page(s): 3522 - 3527
  06/01/2020 Authors: Aliverti E; Tilson JL; Filer DL; Babcock B; Colaneri A; Ocasio J; Gershon TR; Wilhelmsen KC; Dunson DB
• Erbb4 Is Required for Cerebellar Developmentand Malignant Phenotype of Medulloblastoma.
  Cancers (Basel) Volume: 12
  04/17/2020 Authors: Aldaregia J; Errarte P; Olazagoitia-Garmendia A; Gimeno M; Uriz JJ; Gershon TR; Garcia I; Matheu A
• scRNA-seq in medulloblastoma shows cellular heterogeneity and lineage expansion support resistance to SHH inhibitor therapy.
  Nat Commun Volume: 10 Page(s): 5829
  12/20/2019 Authors: Ocasio JK; Babcock B; Malawsky D; Weir SJ; Loo L; Simon JM; Zylka MJ; Hwang D; Dismuke T; Sokolsky M
• SONIC HEDGEHOG SIGNALING PRIMES CEREBELLAR GRANULE NEURON PROGENITORS AND MEDULLOBLASTOMA CELLS FOR APOPTOSIS BY INDUCING PRO-APOPTOTIC BIM
  Volume: 21 Page(s): 187 - 188
  11/01/2019 Authors: Cleveland A; Veleta K; Gershon T
• HYPERLOADED POLY(2-OXAZOLINE) MICELLES AS PERSONALIZED DRUG CARRIERS FOR BRAIN TUMORS
  Volume: 21 Page(s): 272 - 273
  11/01/2019 Authors: Hwang D; Dismuke T; Rosen E; Kagel J; Lim C; Zamboni W; Kabanov A; Gershon T; Sokolsky-Papkov M
• MEDULLOBLASTOMAS RESPOND TO CDK4/6 INHIBITION WITH NANOPARTICLE-DELIVERED PALBOCICLIB WITH ALTERED S-PHASE PROGRESSION
  Volume: 21 Page(s): 94 - 94
  11/01/2019 Authors: Dismuke T; Lim C; Gershon T
• GSK-3 modulates SHH-driven proliferation in postnatal cerebellar neurogenesis and medulloblastoma.
  Development Volume: 146
  10/10/2019 Authors: Ocasio JK; Bates RDP; Rapp CD; Gershon TR
• Hyperloaded poly(2-oxazoline) micelles as personalized drug carriers for brain tumors
  Volume: 258
  08/25/2019 Authors: Hwang D; Dismuke T; Rosen E; Kagel J; Lim C; Zamboni W; Kabanov A; Gershon T; Sokolsky-Papkov M
• DUAL TARGETING OF SHH SIGNALING AND BCL-xL FUNCTION AS A NOVEL TREATMENT FOR MEDULLOBLASTOMA
  Volume: 20 Page(s): 207 - 207
  11/01/2018 Authors: Veleta K; Gershon T
• VISMODEGIB LOADED POLYOXAZOLINE (POx) MICELLES ENHANCE EFFICACY OF VISMODEGIB AND PROLONG MICE SURVIVAL, EMPHASIZE POTENTIAL OF POx MICELLES TO IMPROVE DRUG DELIVERY TO BRAIN TUMORS
  Volume: 20 Page(s): 278 - 278
  11/01/2018 Authors: Hwang D; Lim C; Zhao Y; Liu H; Kabanov AV; Gershon T; Sokolsky-Papkov M
• TARGETING THE RNA-PROCESSING GENE MAGOH AS A NOVEL THERAPY FOR MEDULLOBLASTOMA
  Volume: 20 Page(s): 40 - 40
  11/01/2018 Authors: Ocasio J; Liu H; Gershon T
• A New Way to Treat Brain Tumors: Targeting Proteins Coded by Microcephaly Genes?: Brain tumors and microcephaly arise from opposing derangements regulating progenitor growth. Drivers of microcephaly could be attractive brain tumor targets.
  Bioessays Volume: 40 Page(s): e1700243
  05/01/2018 Authors: Lang PY; Gershon TR
• Pyruvate Kinase Inhibits Proliferation during Postnatal Cerebellar Neurogenesis and Suppresses Medulloblastoma Formation.
  Cancer Res Volume: 77 Page(s): 3217 - 3230
  06/15/2017 Authors: Tech K; Tikunov AP; Farooq H; Morrissy AS; Meidinger J; Fish T; Green SC; Liu H; Li Y; Mungall AJ
• GSK-3 PROMOTES PROLIFERATION DURING POSTNATAL CEREBELLAR DEVELOPMENT AND MAY BE TARGETED IN MEDULLOBLASTOMA THERAPY
  Volume: 19 Page(s): 44 - 44
  06/01/2017 Authors: Ocasio J; Meidinger J; Gershon T
• BCL-XL DISRUPTION AS A POTENTIAL THERAPEUTIC AVENUE FOR MEDULLOBLASTOMA TREATMENT
  Volume: 19 Page(s): 46 - 46
  06/01/2017 Authors: Veleta K; Gershon T
• ATR maintains chromosomal integrity during postnatal cerebellar neurogenesis and is required for medulloblastoma formation.
  Development Volume: 143 Page(s): 4038 - 4052
  11/01/2016 Authors: Lang PY; Nanjangud GJ; Sokolsky-Papkov M; Shaw C; Hwang D; Parker JS; Kabanov AV; Gershon TR
• Psychiatric manifestations as initial presentation for pediatric CNS germ cell tumors, a case series.
  Childs Nerv Syst Volume: 32 Page(s): 1359 - 1362
  08/01/2016 Authors: Malbari F; Gershon TR; Garvin JH; Allen JC; Khakoo Y; Levy AS; Dunkel IJ
• Radiation Sensitivity in a Preclinical Mouse Model of Medulloblastoma Relies on the Function of the Intrinsic Apoptotic Pathway.
  Cancer Res Volume: 76 Page(s): 3211 - 3223
  06/01/2016 Authors: Crowther AJ; Ocasio JK; Fang F; Meidinger J; Wu J; Deal AM; Chang SX; Yuan H; Schmid R; Davis I
• ATR INHIBITION INDUCES DNA DAMAGE AND APOPTOSIS IN MEDULLOBLASTOMA AND ATTENUATES TUMORIGENESIS
  Volume: 18 Page(s): 105 - 105
  06/01/2016 Authors: Lang P; Wu J; Hwang D; Kabanov A; Sokolsky-Papkov M; Gershon T
• AMPK Is Essential to Balance Glycolysis and Mitochondrial Metabolism to Control T-ALL Cell Stress and Survival.
  Cell Metab Volume: 23 Page(s): 649 - 662
  04/12/2016 Authors: Kishton RJ; Barnes CE; Nichols AG; Cohen S; Gerriets VA; Siska PJ; Macintyre AN; Goraksha-Hicks P; de Cubas AA; Liu T
• Essential Function of Dicer in Resolving DNA Damage in the Rapidly Dividing Cells of the Developing and Malignant Cerebellum.
  Cell Rep Volume: 14 Page(s): 216 - 224
  01/12/2016 Authors: Swahari V; Nakamura A; Baran-Gale J; Garcia I; Crowther AJ; Sons R; Gershon TR; Hammond S; Sethupathy P; Deshmukh M
• Aspm sustains postnatal cerebellar neurogenesis and medulloblastoma growth in mice.
  Development Volume: 142 Page(s): 3921 - 3932
  11/15/2015 Authors: Williams SE; Garcia I; Crowther AJ; Li S; Stewart A; Liu H; Lough KJ; O'Neill S; Veleta K; Oyarzabal EA
• Bax deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation.
  Oncogene Volume: 34 Page(s): 3881
  07/01/2015 Authors: Garcia I; Crowther AJ; Gama V; Miller CR; Deshmukh M; Gershon TR
• Bcl-xL DEPENDENCE OF NEURAL PROGENITORS MAY BE EXPLOITED TO IMPROVE MEDULLOBLASTOMA THERAPY
  Volume: 17 Page(s): 32 - 32
  06/01/2015 Authors: Veleta K; Crowther A; Gershon T
• DIFFERENTIAL SPLICING OF PYRUVATE KINASE REGULATES PROGENITOR CELL CYCLE AND MEDULLOBLASTOMA TUMORIGENESIS
  Volume: 17 Page(s): 32 - 32
  06/01/2015 Authors: Tech K; Fish T; Crowther A; Tikunov A; Macdonald J; Gershon T
• GSK-3 PROMOTES PROLIFERATION DURING POSTNATAL CEREBELLAR DEVELOPMENT AND MAY BE TARGETED IN MEDULLOBLASTOMA THERAPY
  Volume: 17 Page(s): 21 - 22
  06/01/2015 Authors: Ocasio J; Gershon T
• SUVmax of Normal Tissues in Pediatric and Adult Patients on FDG PET/MR
  Volume: 56
  05/01/2015 Authors: Sills T; Gershon TR; Chera B; Lin W; Khandani A
• Adaptations of energy metabolism during cerebellar neurogenesis are co-opted in medulloblastoma.
  Cancer Lett Volume: 356 Page(s): 268 - 272
  01/28/2015 Authors: Tech K; Deshmukh M; Gershon TR
• ASC deficiency suppresses proliferation and prevents medulloblastoma incidence.
  Oncogene Volume: 34 Page(s): 394 - 402
  01/15/2015 Authors: Knight ERW; Patel EY; Flowers CA; Crowther AJ; Ting JP; Miller CR; Gershon TR; Deshmukh M
• EFFECTIVENESS OF MEDULLOBLASTOMA TREATMENT IS DETERMINED BY THE DEVELOPMENTAL TIMING OF ONCOGENE ACTIVATION
  Volume: 16 Page(s): 137 - 137
  06/01/2014 Authors: Gershon T; Crowther A; Wu J; Liu H; Fang F; Davis I
• Early-onset stroke and vasculopathy associated with mutations in ADA2.
  N Engl J Med Volume: 370 Page(s): 911 - 920
  03/06/2014 Authors: Zhou Q; Yang D; Ombrello AK; Zavialov AV; Toro C; Zavialov AV; Stone DL; Chae JJ; Rosenzweig SD; Bishop K
• Tonic activation of Bax primes neural progenitors for rapid apoptosis through a mechanism preserved in medulloblastoma.
  J Neurosci Volume: 33 Page(s): 18098 - 18108
  11/13/2013 Authors: Crowther AJ; Gama V; Bevilacqua A; Chang SX; Yuan H; Deshmukh M; Gershon TR
• Bax deficiency prolongs cerebellar neurogenesis, accelerates medulloblastoma formation and paradoxically increases both malignancy and differentiation.
  Oncogene Volume: 32 Page(s): 2304 - 2314
  05/02/2013 Authors: Garcia I; Crowther AJ; Gama V; Miller CR; Deshmukh M; Gershon TR
• SENSITIVITY OF MEDULLOBLASTOMA TO RADIATION REQUIRES AN INTACT MITOCHONDRIAL APOPTOTIC PATHWAY
  Volume: 15 Page(s): 16 - 16
  04/01/2013 Authors: Crowther A; Chang S; Yuan H; Deshmukh M; Gershon T
• Medulloblastoma is Primed for Rapid Apoptosis by Constitutively Active Bax: a Unique Vulnerability Which May Be Exploited for Therapeutic Benefit
  Volume: 48 Page(s): 30 - 30
  11/01/2012 Authors: Gershon T; Crowther A; Garcia I; Gama V; Allard D; Miller CR; Deshmukh M
• Sonic Hedgehog Pathway Activation Reveals Hexokinase-2-mediated Aerobic Glycolysis as a Novel Target for Medulloblastoma Therapy
  Volume: 48 Page(s): 175 - 176
  11/01/2012 Authors: Gershon T; Crowther A; Tikunov A; Garcia I; Yuan H; Macdonald J; Deshmukh M
• MEDULLOBLASTOMA IS PRIMED FOR RAPID APOPTOSIS BY CONSTITUTIVELY ACTIVE BAX AND IS HIGHLY SENSITIVE TO BH3 MIMETIC THERAPY
  Volume: 14 Page(s): 118 - 118
  10/01/2012 Authors: Gershon T; Crowther A; Garcia I; Gama V; Yuan H; Chang S; Deshmukh M
• ASPM, A TARGET OF SONIC HEDGEHOG, IS A KEY ELEMENT IN CEREBELLAR DEVELOPMENT AND MEDULLOBLASTOMA PATHOGENESIS
  Volume: 14 Page(s): 94 - 95
  06/01/2012 Authors: Garcia I; Crowther AJ; Gershon TR
• BAX-RESISTANCE PLAYS AN ESSENTIAL ROLE IN MEDULLOBLASTOMA FORMATION
  Volume: 14 Page(s): 94 - 94
  06/01/2012 Authors: Garcia I; Crowther AJ; Gama V; Miller CR; Deshmukh M; Gershon TR
• Hexokinase-2-Mediated Aerobic Glycolysis as a Novel Target for Medulloblastoma Therapy
  Volume: 72 Page(s): S143 - S144
  01/01/2012 Authors: Gershon TR; Crowther A; Tikunov A; Yuan H; Macdonald J; Deshmukh M
• Novel use of zolpidem in cerebellar mutism syndrome.
  J Pediatr Hematol Oncol Volume: 33 Page(s): 148 - 149
  03/01/2011 Authors: Shyu C; Burke K; Souweidane MM; Dunkel IJ; Gilheeney SW; Gershon T; Khakoo Y
• Tbata modulates thymic stromal cell proliferation and thymus function.
  J Exp Med Volume: 207 Page(s): 2521 - 2532
  10/25/2010 Authors: Flomerfelt FA; El Kassar N; Gurunathan C; Chua KS; League SC; Schmitz S; Gershon TR; Kapoor V; Yan X-Y; Schwartz RH
• Expression of the neuron-specific protein CHD5 is an independent marker of outcome in neuroblastoma.
  Mol Cancer Volume: 9 Page(s): 277
  10/15/2010 Authors: Garcia I; Mayol G; Rodrguez E; Suol M; Gershon TR; Ros J; Cheung N-KV; Kieran MW; George RE; Perez-Atayde AR
• Intensive multimodality therapy for patients with stage 4a metastatic retinoblastoma.
  Pediatr Blood Cancer Volume: 55 Page(s): 55 - 59
  07/15/2010 Authors: Dunkel IJ; Khakoo Y; Kernan NA; Gershon T; Gilheeney S; Lyden DC; Wolden SL; Orjuela M; Gardner SL; Abramson DH
• INTERFERON SIGNALING: A DRIVING FORCE FOR NEURAL PROGENITOR PROLIFERATION AND A NOVEL TARGET FOR MEDULLOBLASTOMA
  Volume: 12 Page(s): II3 - II3
  06/01/2010 Authors: Gershon TR; Deshmukh M
• A TRIAL OF INTRA-OMMAYA (IO) RADIOIMMUNOTHERAPY (RIT), REDUCED-DOSE EXTERNAL BEAM CRANIOSPINAL RADIOTHERAPY (RT) WITH INTENSITY-MODULATED RADIOTHERAPY (IMRT) BOOST, AND CHEMOTHERAPY FOR PATIENTS WITH STANDARD-RISK MEDULLOBLASTOMA
  Volume: 12 Page(s): II60 - II60
  06/01/2010 Authors: Dunkel IJ; Wolden SL; Souweidane MM; Sklar CA; Khakoo Y; Larson SM; Becher OJ; Gershon TR; Gilheeney SW; Lyden DC
• Enteric neural crest differentiation in ganglioneuromas implicates Hedgehog signaling in peripheral neuroblastic tumor pathogenesis.
  PLoS One Volume: 4 Page(s): e7491
  10/16/2009 Authors: Gershon TR; Shiraz A; Qin L-X; Gerald WL; Kenney AM; Cheung N-K
• Effect of the combination of retinoic acid and rapamycin on cerebellar granule cell and medulloblastoma proliferation
  Volume: 27
  05/20/2009 Authors: Gershon TR; Shirazi A; Kenney AM
• Late extraneural medulloblastoma relapse: Case reports
  Volume: 10 Page(s): 481 - 481
  06/01/2008 Authors: Curran K; Dunkel I; Khakoo Y; Lyden D; Gilheeney S; Becher O; Gershon T
• Novel use of zolpidem in cerebellar mutism syndrome
  Volume: 10 Page(s): 484 - 484
  06/01/2008 Authors: Shyu C; Souweidane M; Dunkel I; Gilheeney S; Gershon T; Khakoo Y
• Genetically engineered mouse model of brainstem glioma
  Volume: 10 Page(s): 383 - 383
  06/01/2008 Authors: Becher O; Hambardzumyan D; Gershon T; Holland E
• Outcomes using IMRT tumor-bed boost for medulloblastoma
  Volume: 72 Page(s): S79 - S80
  01/01/2008 Authors: Polkinghom WR; Dunkel IJ; Souweidane MM; Khakoo Y; Lyden DC; Gershon TR; Gilheeney SW; Chen WC; Wolden SL
• A role for NUMB primitive neuro-ectodermal tumors (PNETs)
  Volume: 62 Page(s): S108 - S108
  01/01/2007 Authors: Gershon TR; Xiao Y; Gerald WL
• Synapse formation in the enteric nervous system: Interaction between neuroligins and neurexins
  Volume: 24 Page(s): 523 - 523
  12/01/2006 Authors: D'Autraux F; Scheiffele P; Gershon T; Levanon D; Chalazonitis A; Gershon MD
• Prevalence of EEG abnormalities in a pediatric cancer population
  Volume: 8 Page(s): 480 - 480
  10/01/2006 Authors: Khakoo Y; Gershon T; Solomon G; Merchant S
• Medulloblastoma: therapy and biologic considerations.
  Curr Neurol Neurosci Rep Volume: 6 Page(s): 200 - 206
  05/01/2006 Authors: Gershon TR; Becher OJ
• Temporally regulated neural crest transcription factors distinguish neuroectodermal tumors of varying malignancy and differentiation.
  Neoplasia Volume: 7 Page(s): 575 - 584
  06/01/2005 Authors: Gershon TR; Oppenheimer O; Chin SS; Gerald WL
• Cellular expression of a leech netrin suggests roles in the formation of longitudinal nerve tracts and in regional innervation of peripheral targets.
  J Neurobiol Volume: 40 Page(s): 103 - 115
  07/01/1999 Authors: Gan WB; Wong VY; Phillips A; Ma C; Gershon TR; Macagno ER
• Two receptor tyrosine phosphatases of the LAR family are expressed in the developing leech by specific central neurons as well as select peripheral neurons, muscles, and other cells.
  J Neurosci Volume: 18 Page(s): 2991 - 3002
  04/15/1998 Authors: Gershon TR; Baker MW; Nitabach M; Wu P; Macagno ER
• The leech receptor protein tyrosine phosphatase HmLAR2 is concentrated in growth cones and is involved in process outgrowth.
  Development Volume: 125 Page(s): 1183 - 1190
  04/01/1998 Authors: Gershon TR; Baker MW; Nitabach M; Macagno ER
• New electrical properties of neurons induced by a homeoprotein.
  J Neurobiol Volume: 33 Page(s): 11 - 17
  07/01/1997 Authors: Aisemberg GO; Gershon TR; Macagno ER
• Peripheral organs control central neurogenesis in the leech.
  Nature Volume: 346 Page(s): 855 - 858
  08/30/1990 Authors: Baptista CA; Gershon TR; Macagno ER
• Occurrence of cells containing paracrystalloid material in the intestinal lamina propria of the hibernating bat Myotis lucifugus.
  Anat Rec Volume: 218 Page(s): 149 - 156
  06/01/1987 Authors: Payette RF; Gershon TR; Gershon MD; Nunez EA