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Profile

Thota Ganesh PhD

  • Department of Pharmacology & Chemical Biology
    Associate Professor
  • (404) 727-7393
  • tganesh@emory.edu
  • My service/philonthapic activities
  • My Laboratory
  • Emory University School of Medicine
    Pharmacology
    1510 Clifton Rd, Room 5019
Head shot of Thota Ganesh

Overview

The overall goal of my research is to work with disease oriented biomedical research investigators to develop small molecule drugs for a variety of medically unmet CNS and peripheral diseases. We currently focussing on to develop novel small molecule therapeutic agents to treat Alzheimer's disease and Epilepsy.

Academic Appointment

  • Associate Professor, Pharmacology, Emory University School of Medicine

Education

Degrees

  • PhD from Osmania University
  • BS from Osmania University
  • PhD from Osmania University

Research

Publications

  • Toll-like receptor 7 (TLR7)-mediated antiviral response protects mice from lethal SARS-CoV-2 infection.
    J Virol Volume: 99 Page(s): e0166824
    05/20/2025 Authors: Ghimire R; Shrestha R; Amaradhi R; Liu L; More S; Ganesh T; Ford AK; Channappanavar R
  • Bisbiguanide analogs induce mitochondrial stress to inhibit lung cancer cell invasion.
    iScience Volume: 27 Page(s): 109591
    04/19/2024 Authors: Knippler CM; Arnst JL; Robinson IE; Matsuk V; Khatib TO; Harvey RD; Shanmugam M; Mouw JK; Fu H; Ganesh T
  • Novel NADPH Oxidase-2 Inhibitors as Potential Anti-Inflammatory and Neuroprotective Agents.
    Antioxidants (Basel) Volume: 12
    08/23/2023 Authors: Juric M; Rawat V; Amaradhi R; Zielonka J; Ganesh T
  • Targeting EP2 Receptor for Drug Discovery: Strengths, Weaknesses, Opportunities, and Threats (SWOT) Analysis.
    J Med Chem Volume: 66 Page(s): 9313 - 9324
    07/27/2023 Authors: Ganesh T
  • Preclinical development of an EP2 antagonist for post-seizure cognitive deficits.
    Neuropharmacology Volume: 224 Page(s): 109356
    02/15/2023 Authors: Varvel NH; Amaradhi R; Espinosa-Garcia C; Duddy S; Franklin R; Banik A; Alemn-Ruiz C; Blackmer-Raynolds L; Wang W; Honore T
  • Temporal Expression of Neuroinflammatory and Oxidative Stress Markers and Prostaglandin E2 Receptor EP2 Antagonist Effect in a Rat Model of Epileptogenesis.
    ACS Pharmacol Transl Sci Volume: 6 Page(s): 128 - 138
    01/13/2023 Authors: Rawat V; Eastman CL; Amaradhi R; Banik A; Fender JS; Dingledine RJ; D'Ambrosio R; Ganesh T
  • Pharmacological antagonism of EP2 receptor does not modify basal cardiovascular and respiratory function, blood cell counts, and bone morphology in animal models.
    Biomed Pharmacother Volume: 147 Page(s): 112646
    03/01/2022 Authors: Rawat V; Banik A; Amaradhi R; Rojas A; Taval S; Nagy T; Dingledine R; Ganesh T
  • Second-Generation Prostaglandin Receptor EP2 Antagonist, TG8-260, with High Potency, Selectivity, Oral Bioavailability, and Anti-Inflammatory Properties.
    ACS Pharmacol Transl Sci Volume: 5 Page(s): 118 - 133
    02/11/2022 Authors: Amaradhi R; Mohammed S; Banik A; Franklin R; Dingledine R; Ganesh T
  • Microbial metabolite delta-valerobetaine is a diet-dependent obesogen.
    Nat Metab Volume: 3 Page(s): 1694 - 1705
    12/01/2021 Authors: Liu KH; Owens JA; Saeedi B; Cohen CE; Bellissimo MP; Naudin C; Darby T; Druzak S; Maner-Smith K; Orr M
  • Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer's disease.
    J Neuroinflammation Volume: 18 Page(s): 273
    11/20/2021 Authors: Banik A; Amaradhi R; Lee D; Sau M; Wang W; Dingledine R; Ganesh T
  • A Novel Second-Generation EP2 Receptor Antagonist Reduces Neuroinflammation and Gliosis After Status Epilepticus in Rats.
    Neurotherapeutics Volume: 18 Page(s): 1207 - 1225
    04/01/2021 Authors: Rojas A; Amaradhi R; Banik A; Jiang C; Abreu-Melon J; Wang S; Dingledine R; Ganesh T
  • Peripheral Myeloid Cell EP2 Activation Contributes to the Deleterious Consequences of Status Epilepticus.
    J Neurosci Volume: 41 Page(s): 1105 - 1117
    02/03/2021 Authors: Varvel NH; Espinosa-Garcia C; Hunter-Chang S; Chen D; Biegel A; Hsieh A; Blackmer-Raynolds L; Ganesh T; Dingledine R
  • Quinazolin-derived myeloperoxidase inhibitor suppresses influenza A virus-induced reactive oxygen species, pro-inflammatory mediators and improves cell survival.
    PLoS One Volume: 16 Page(s): e0254632
    01/01/2021 Authors: De La Cruz JA; Ganesh T; Diebold BA; Cao W; Hofstetter A; Singh N; Kumar A; McCoy J; Ranjan P; Smith SME
  • Azaindole therapeutic agents.
    Bioorg Med Chem Volume: 28 Page(s): 115830
    12/15/2020 Authors: Motati DR; Amaradhi R; Ganesh T
  • Inhibition of the prostaglandin EP2 receptor prevents long-term cognitive impairment in a model of systemic inflammation.
    Brain Behav Immun Health Volume: 8 Page(s): 100132
    10/01/2020 Authors: Jiang C; Caskurlu A; Ganesh T; Dingledine R
  • Modulating neuroinflammation and oxidative stress to prevent epilepsy and improve outcomes after traumatic brain injury.
    Neuropharmacology Volume: 172 Page(s): 107907
    08/01/2020 Authors: Eastman CL; D'Ambrosio R; Ganesh T
  • An Agonist Dependent Allosteric Antagonist of Prostaglandin EP2 Receptors.
    ACS Chem Neurosci Volume: 11 Page(s): 1436 - 1446
    05/20/2020 Authors: Jiang C; Amaradhi R; Ganesh T; Dingledine R
  • A Noncompetitive and Selective Prostaglandin EP2 Antagonist with Anti-inflammatory Property
    Volume: 34
    04/01/2020 Authors: Jiang C; Amaradhi R; Ganesh T; Dingledine R
  • Potent, Selective, Water Soluble, Brain-Permeable EP2 Receptor Antagonist for Use in Central Nervous System Disease Models.
    J Med Chem Volume: 63 Page(s): 1032 - 1050
    02/13/2020 Authors: Amaradhi R; Banik A; Mohammed S; Patro V; Rojas A; Wang W; Motati DR; Dingledine R; Ganesh T
  • A rat model of organophosphate-induced status epilepticus and the beneficial effects of EP2 receptor inhibition.
    Neurobiol Dis Volume: 133 Page(s): 104399
    01/01/2020 Authors: Rojas A; Ganesh T; Wang W; Wang J; Dingledine R
  • Novel Microglia Cell Line Expressing the Human EP2 Receptor.
    ACS Chem Neurosci Volume: 10 Page(s): 4280 - 4292
    10/16/2019 Authors: Rojas A; Banik A; Chen D; Flood K; Ganesh T; Dingledine R
  • Development of water soluble, brain permeable EP2 receptor antagonist: Lead-optimization and in vitro proof-of-concept studies
    Volume: 257
    03/31/2019 Authors: Amaradhi R; Banik A; Mohammed S; Patro V; Rojas A; Wang W; Dingledine R; Ganesh T
  • The COX-2/prostanoid signaling cascades in seizure disorders.
    Expert Opin Ther Targets Volume: 23 Page(s): 1 - 13
    01/01/2019 Authors: Rojas A; Chen D; Ganesh T; Varvel NH; Dingledine R
  • 5xFAD Mice Display Sex-Dependent Inflammatory Gene Induction During the Prodromal Stage of Alzheimer's Disease.
    J Alzheimers Dis Volume: 70 Page(s): 1259 - 1274
    01/01/2019 Authors: Manji Z; Rojas A; Wang W; Dingledine R; Varvel NH; Ganesh T
  • Peripherally Restricted, Highly Potent, Selective, Aqueous-Soluble EP2 Antagonist with Anti-Inflammatory Properties.
    Mol Pharm Volume: 15 Page(s): 5809 - 5817
    12/03/2018 Authors: Ganesh T; Banik A; Dingledine R; Wang W; Amaradhi R
  • Discovery of 2-Piperidinyl Phenyl Benzamides and Trisubstituted Pyrimidines as Positive Allosteric Modulators of the Prostaglandin Receptor EP2.
    ACS Chem Neurosci Volume: 9 Page(s): 699 - 707
    04/18/2018 Authors: Jiang J; Van TM; Ganesh T; Dingledine R
  • Prostaglandin dehydrogenase is a target for successful induction of cervical ripening.
    Proc Natl Acad Sci U S A Volume: 114 Page(s): E6427 - E6436
    08/01/2017 Authors: Kishore AH; Liang H; Kanchwala M; Xing C; Ganesh T; Akgul Y; Posner B; Ready JM; Markowitz SD; Word RA
  • Ethylatropine Bromide as a Peripherally Restricted Muscarinic Antagonist.
    ACS Chem Neurosci Volume: 8 Page(s): 712 - 717
    04/19/2017 Authors: Rojas A; Ganesh T; Walker A; Dingledine R
  • Inhibition of pilocarpine-induced fluid secretion by ethylatropine bromide
    Volume: 253
    04/02/2017 Authors: Ganesh T; Rojas A; Walker A; Dingledine R
  • Structure Activity Relationship (SAR) studies of EP2 receptor antagonists
    Volume: 253
    04/02/2017 Authors: Ganesh T; Dingledine R
  • Inhibition of the prostaglandin E2 receptor EP2 prevents status epilepticus-induced deficits in the novel object recognition task in rats.
    Neuropharmacology Volume: 110 Page(s): 419 - 430
    11/01/2016 Authors: Rojas A; Ganesh T; Manji Z; O'neill T; Dingledine R
  • Thioxo-dihydroquinazolin-one Compounds as Novel Inhibitors of Myeloperoxidase.
    ACS Med Chem Lett Volume: 6 Page(s): 1047 - 1052
    10/08/2015 Authors: Li Y; Ganesh T; Diebold BA; Zhu Y; McCoy JW; Smith SME; Sun A; Lambeth JD
  • EP2 Receptor Signaling Regulates Microglia Death.
    Mol Pharmacol Volume: 88 Page(s): 161 - 170
    07/01/2015 Authors: Fu Y; Yang M-S; Jiang J; Ganesh T; Joe E; Dingledine R
  • Evaluation of WO 2012/177618 A1 and US-2014/0179750 A1: novel small molecule antagonists of prostaglandin-E2 receptor EP2.
    Expert Opin Ther Pat Volume: 25 Page(s): 837 - 844
    07/01/2015 Authors: Ganesh T
  • Inhibition of the prostaglandin EP2 receptor is neuroprotective and accelerates functional recovery in a rat model of organophosphorus induced status epilepticus.
    Neuropharmacology Volume: 93 Page(s): 15 - 27
    06/01/2015 Authors: Rojas A; Ganesh T; Lelutiu N; Gueorguieva P; Dingledine R
  • Therapeutic window for cyclooxygenase-2 related anti-inflammatory therapy after status epilepticus.
    Neurobiol Dis Volume: 76 Page(s): 126 - 136
    04/01/2015 Authors: Jiang J; Yang M-S; Quan Y; Gueorguieva P; Ganesh T; Dingledine R
  • Context-dependent GluN2B-selective inhibitors of NMDA receptor function are neuroprotective with minimal side effects.
    Neuron Volume: 85 Page(s): 1305 - 1318
    03/18/2015 Authors: Yuan H; Myers SJ; Wells G; Nicholson KL; Swanger SA; Lyuboslavsky P; Tahirovic YA; Menaldino DS; Ganesh T; Wilson LJ
  • Dual EZH2 and EHMT2 histone methyltransferase inhibition increases biological efficacy in breast cancer cells.
    Clin Epigenetics Volume: 7 Page(s): 84
    01/01/2015 Authors: Curry E; Green I; Chapman-Rothe N; Shamsaei E; Kandil S; Cherblanc FL; Payne L; Bell E; Ganesh T; Srimongkolpithak N
  • Development of second generation EP2 antagonists with high selectivity.
    Eur J Med Chem Volume: 82 Page(s): 521 - 535
    07/23/2014 Authors: Ganesh T; Jiang J; Dingledine R
  • Prostanoid receptor EP2 as a therapeutic target.
    J Med Chem Volume: 57 Page(s): 4454 - 4465
    06/12/2014 Authors: Ganesh T
  • High-throughput assays for superoxide and hydrogen peroxide: design of a screening workflow to identify inhibitors of NADPH oxidases.
    J Biol Chem Volume: 289 Page(s): 16176 - 16189
    06/06/2014 Authors: Zielonka J; Cheng G; Zielonka M; Ganesh T; Sun A; Joseph J; Michalski R; O'Brien WJ; Lambeth JD; Kalyanaraman B
  • Lead optimization studies of cinnamic amide EP2 antagonists.
    J Med Chem Volume: 57 Page(s): 4173 - 4184
    05/22/2014 Authors: Ganesh T; Jiang J; Yang M-S; Dingledine R
  • Synthesis of isotopically labeled epothilones.
    J Labelled Comp Radiopharm Volume: 57 Page(s): 78 - 81
    02/01/2014 Authors: Ganesh T; Brodie PJ; Banerjee A; Bane S; Kingston DGI
  • Cyclooxygenase-2 in epilepsy.
    Epilepsia Volume: 55 Page(s): 17 - 25
    01/01/2014 Authors: Rojas A; Jiang J; Ganesh T; Yang M-S; Lelutiu N; Gueorguieva P; Dingledine R
  • Discovery and characterization of carbamothioylacrylamides as EP2 selective antagonists.
    ACS Med Chem Lett Volume: 4 Page(s): 616 - 621
    07/11/2013 Authors: Ganesh T; Jiang J; Shashidharamurthy R; Dingledine R
  • A novel quinazolin-derived reactive oxygen species-inhibitor suppresses influenza A virus-induced inflammatory mediators and leads to enhanced survival in mice
    Volume: 190
    05/01/2013 Authors: Gangappa S; De La Cruz J; Ganesh T; Diebold B; Cao W; Smith S; Taylor A; Singh N; Hofstetter A; Kumar A
  • Inhibition of the prostaglandin receptor EP2 following status epilepticus reduces delayed mortality and brain inflammation.
    Proc Natl Acad Sci U S A Volume: 110 Page(s): 3591 - 3596
    02/26/2013 Authors: Jiang J; Quan Y; Ganesh T; Pouliot WA; Dudek FE; Dingledine R
  • High-Throughput Screening (HTS) Assay for Identifying Potent and Selective Small-Molecule Inhibitors of NADPH Oxidases
    Volume: 53 Page(s): S122 - S122
    11/01/2012 Authors: Zielonka J; Zielonka M; Ganesh T; Sun A; Cheng G; Michalski R; O'Brien W; Lambeth D; Kalyanaraman B
  • Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits.
    Chem Biol Volume: 19 Page(s): 752 - 763
    06/22/2012 Authors: Smith SME; Min J; Ganesh T; Diebold B; Kawahara T; Zhu Y; McCoy J; Sun A; Snyder JP; Fu H
  • Small molecule antagonist reveals seizure-induced mediation of neuronal injury by prostaglandin E2 receptor subtype EP2.
    Proc Natl Acad Sci U S A Volume: 109 Page(s): 3149 - 3154
    02/21/2012 Authors: Jiang J; Ganesh T; Du Y; Quan Y; Serrano G; Qui M; Speigel I; Rojas A; Lelutiu N; Dingledine R
  • Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation.
    Int J Cancer Volume: 129 Page(s): 2744 - 2755
    12/01/2011 Authors: Thaiparambil JT; Bender L; Ganesh T; Kline E; Patel P; Liu Y; Tighiouart M; Vertino PM; Harvey RD; Garcia A
  • Inhibitors of NADPH Oxidase Decrease Peroxynitrite Formation in Activated Macrophages
    Volume: 51 Page(s): S53 - S53
    11/01/2011 Authors: Zielonka J; Zielonka M; Ganesh T; Sun A; Lambeth D; Kalyanaraman B
  • Identification and Characterization of Novel NADPH Oxidase Inhibitors for Suppression of Influenza a virus-induced Lung Inflammation
    Volume: 51 Page(s): S108 - S108
    11/01/2011 Authors: Sun A; De la Cruz J; Ganesh T; Taylor A; Diebold B; Smith SME; Zhu Y; McCoy J; Gangappa S; Lambeth JD
  • Ebselen Congeners Inhibit NADPH-oxidase 2 (Nox2)-Dependent Superoxide Generation by Interrupting the Binding of Regulatory Subunits
    Volume: 51 Page(s): S98 - S98
    11/01/2011 Authors: Smith SME; Min J; Ganesh T; Kawahara T; Diebold B; Zhu Y; McCoy J; Sun A; Snyder JP; Fu H
  • Lipocalin-2 Deficiency Increases Gut Bacterial Burden and Excerbates Dextran Sulfate Sodium (DSS) Induced Murine Colitis
    Volume: 140 Page(s): S496 - S496
    05/01/2011 Authors: Aitken JD; Carvalho FA; Fifadara N; Ganesh T; Gewirtz AT; Vijay-Kumar M
  • Withaferin A inhibits breast cancer invasion and metastasis at subcytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation
    CANCER RESEARCH Volume: 71
    04/15/2011 Authors: Thaiparambil JT; Bender L; Ganesh T; Kline E; Patel P; Liu Y; Tighiouart M; Vertino PM; Harvey RD; Garcia A
  • Adding a lysine mimic in the design of potent inhibitors of histone lysine methyltransferases.
    J Mol Biol Volume: 400 Page(s): 1 - 7
    07/02/2010 Authors: Chang Y; Ganesh T; Horton JR; Spannhoff A; Liu J; Sun A; Zhang X; Bedford MT; Shinkai Y; Snyder JP
  • Novel epothilone lactones by an unusual diversion of the Grubbs' metathesis reaction.
    Chem Commun (Camb) Volume: 46 Page(s): 2019 - 2021
    03/28/2010 Authors: Chen Q-H; Ganesh T; Jiang Y; Banerjee A; Sharma S; Bane S; Snyder JP; Kingston DGI
  • Neuroprotection by selective allosteric potentiators of the EP2 prostaglandin receptor.
    Proc Natl Acad Sci U S A Volume: 107 Page(s): 2307 - 2312
    02/02/2010 Authors: Jiang J; Ganesh T; Du Y; Thepchatri P; Rojas A; Lewis I; Kurtkaya S; Li L; Qui M; Serrano G
  • Vimentin: A Novel Chemopreventive Target for Breast Cancer Metastasis
    Volume: 69 Page(s): 786S - 786S
    12/15/2009 Authors: Thaiparambil JT; Bender L; Kline E; Ganesh T; Snyder JP; Liotta D; Marcus A
  • Cancer and virus leads by HTS, chemical design and SEA data mining.
    Curr Top Med Chem Volume: 9 Page(s): 1159 - 1171
    01/01/2009 Authors: Thepchatri P; Min J; Ganesh T; Du Y; Lewis I; Kurtkaya S; Prussia A; Li L; Sneed B; Plemper RK
  • Design, synthesis and biological evaluation of bridged epothilone D analogues.
    Org Biomol Chem Volume: 6 Page(s): 4542 - 4552
    12/21/2008 Authors: Chen Q-H; Ganesh T; Brodie P; Slebodnick C; Jiang Y; Banerjee A; Bane S; Snyder JP; Kingston DGI
  • Synthesis and SAR study of N-(4-hydroxy-3-(2-hydroxynaphthalene-1-yl)phenyl)-arylsulfonamides: heat shock protein 90 (Hsp90) inhibitors with submicromolar activity in an in vitro assay.
    Bioorg Med Chem Lett Volume: 18 Page(s): 4982 - 4987
    09/15/2008 Authors: Ganesh T; Thepchatri P; Li L; Du Y; Fu H; Snyder JP; Sun A
  • ORGN 106-Design, synthesis and biological evaluation of C4-C9 bridged epothilone B and D analogs
    Volume: 236
    08/17/2008 Authors: Jiang Y; Ganesh T; Brodie PJ; Bane S; Kingston DGI; Liotta DC; Snyder JP
  • Discovery of aminoquinolines as a new class of potent inhibitors of heat shock protein 90 (Hsp90): Synthesis, biology, and molecular modeling.
    Bioorg Med Chem Volume: 16 Page(s): 6903 - 6910
    07/15/2008 Authors: Ganesh T; Min J; Thepchatri P; Du Y; Li L; Lewis I; Wilson L; Fu H; Chiosis G; Dingledine R
  • Enhanced microtubule binding and tubulin assembly properties of conformationally constrained paclitaxel derivatives.
    Biochemistry Volume: 46 Page(s): 11514 - 11527
    10/16/2007 Authors: Shanker N; Kingston DGI; Ganesh T; Yang C; Alcaraz AA; Geballe MT; Banerjee A; McGee D; Snyder JP; Bane S
  • Improved biochemical strategies for targeted delivery of taxoids.
    Bioorg Med Chem Volume: 15 Page(s): 3597 - 3623
    06/01/2007 Authors: Ganesh T
  • Evaluation of the tubulin-bound paclitaxel conformation: synthesis, biology, and SAR studies of C-4 to C-3' bridged paclitaxel analogues.
    J Med Chem Volume: 50 Page(s): 713 - 725
    02/22/2007 Authors: Ganesh T; Yang C; Norris A; Glass T; Bane S; Ravindra R; Banerjee A; Metaferia B; Thomas SL; Giannakakou P
  • Promotion of tubulin assembly by poorly soluble taxol analogs.
    Anal Biochem Volume: 360 Page(s): 56 - 62
    01/01/2007 Authors: Sharma S; Ganesh T; Kingston DGI; Bane S
  • Design, synthesis, and bioactivity of simplified paclitaxel analogs based on the T-Taxol bioactive conformation.
    Bioorg Med Chem Volume: 14 Page(s): 3447 - 3454
    05/15/2006 Authors: Ganesh T; Norris A; Sharma S; Bane S; Alcaraz AA; Snyder JP; Kingston DGI
  • Design, synthesis and biological investigation of conformationally constrained epothilone D analogs
    Volume: 231
    03/26/2006 Authors: Ganesh T; Brodie P; Bane S; Sharma S; Ravindra R; Snyder JP; Kingston DGI
  • Computational analysis of T-Taxol and highly modified taxane analogs
    Volume: 231
    03/26/2006 Authors: Alcaraz AA; Ganesh T; Yang C; Sharma S; Norris A; Mehta AK; Bane S; Kingston DGI; Snyder JP
  • Design, synthesis, and bioactivity of simplified paclitaxel analogs based on the T-Taxol bioactive conformation
    Volume: 229 Page(s): U160 - U160
    03/13/2005 Authors: Ganesh T; Norris A; Sharma S; Bane S; Lakdawala AS; Snyder JP; Kingston DGI
  • Evaluation of the bioactive tubuilin-binding paclitaxel conformation: Synthesis and biological evaluation of C4 to C3 '-phenyl bridged paclitaxel analogs.
    Volume: 229 Page(s): U193 - U193
    03/13/2005 Authors: Ganesh T; Bane S; Ravindra R; Shanker N; Lakdawala AS; Snyder JP; Norris A; Kingston DGI
  • Microtubule binding, stabilization and cytotoxicities of conformationally constrained taxol derivatives
    Volume: 15 Page(s): 294A - 294A
    11/01/2004 Authors: Shanker N; Ravindra R; Ganesh T; Morris A; Lakdawala AS; Giannakakou A; Thomas S; Kingston DG; Snyder JP; Bane SL
  • The bioactive Taxol conformation on beta-tubulin: experimental evidence from highly active constrained analogs.
    Proc Natl Acad Sci U S A Volume: 101 Page(s): 10006 - 10011
    07/06/2004 Authors: Ganesh T; Guza RC; Bane S; Ravindra R; Shanker N; Lakdawala AS; Snyder JP; Kingston DGI
  • Taxol pharmacophore: Experimental evidence from a highly constrained analog and REDOR NMR.
    Volume: 227 Page(s): U41 - U41
    03/28/2004 Authors: Kingston DGI; Ganesh T; Schilling JK; Guza RC; Bane S; Shanker N; Ravindra R; Snyder JP; Lakdawala A; Cegelski L
  • Synthesis and biological evaluation of fluorescently labeled epothilone analogs for tubulin binding studies.
    Volume: 226 Page(s): U49 - U49
    09/01/2003 Authors: Ganesh T; Kingston DGI; Bane S; Shanker N; Schilling JK
  • Asymmetric synthesis of the putative structure of (-)-oryzoxymycin.
    Org Lett Volume: 5 Page(s): 239 - 242
    02/06/2003 Authors: Bunnage ME; Ganesh T; Masesane IB; Orton D; Steel PG
  • Kinetic resolution of (+/-)-trans-3-acetoxy-2-phenyl-1,5-benzodioxapine by pig liver acetone powder
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY Volume: 38 Page(s): 397 - 399
    04/01/1999 Authors: Ganesh T; Sharma KK; Krupadanam GLD
  • A facile synthesis of 2-hydroxy-2-aryl 1,4-benzodioxanes
    SYNTHETIC COMMUNICATIONS Volume: 29 Page(s): 2069 - 2078
    01/01/1999 Authors: Ganesh T; Kumar CH; Krupadanam GLD
  • A new synthesis of heterocyclic compounds with 1,5-benzodioxapine, 1,5-benzodiazepine, 1,5-benzothiazepine ring systems
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY Volume: 37 Page(s): 34 - 38
    01/01/1998 Authors: Ganesh T; Krupadanam GLD
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