Timothy Buchman PhD/MD
Overview
During his 2009-2018 service as the founding director of the Emory Critical Care Center, Dr. Buchman integrated ICUs throughout the Emory Healthcare system and brought together clinicians and investigators from diverse disciplines to conduct research to define best clinical practices and inform public health policy.
Dr. Buchman's research spans the bench-to-bedside and encompasses studies of physiological dynamics, predictive biology, patient monitoring, the genetics of sepsis, and ICU end-of-life care.
In 2014, Dr. Buchman was the founding medical director of the Emory Electronic ICU. Funded by a $10.7 million Health Care Innovation Award from the Centers for Medicare and Medicaid Services (CMS), the Emory eICU program was designed as a collaborative network supporting critical care units at Emory University Hospital, Emory University Hospital Midtown, Emory Saint Joseph's Hospital, Emory Johns Creek Hospital, and East Georgia Regional Medical Center in Statesboro, Georgia. Health care workers monitored the five hospitals from a control room outfitted with equipment at Emory Saint Joseph's Hospital, providing continuous, 24/7 monitoring of critical care patients and access to intensivist physicians and other support staff on night and weekend shifts. In 2017, a CMS report on the program determined the eICU program reduced length of patient stays in the ICU, resulted in fewer admissions, lowered costs by millions of dollars, and helped solve the shortage of critical care intensivists. In 2018, Emory and Dr. Buchman expanded the program to Royal Perth Hospital in Australia.
Academic Appointment
- Professor of Biomedical Informatics, Department of Surgery, Emory University School of Medicine
- Medical Director, Electronic ICU Service, Emory Healthcare
- Professor of Anesthesiology, Department of Surgery, Emory University School of Medicine
- Professor of Surgery, Department of Surgery, Emory University School of Medicine
Education
Degrees
- MD from University of Chicago, Pritzker School of Medicine
- PhD from University of Chicago
- M.S. from University of Chicago
- BS from University of Chicago
Research
Focus
-
Bench-to-bedside translational research in issues pertinent to critical care.
Dr. Buchman's research interests span the molecular mechanisms underlying the multiple organ dysfunction syndrome, end-of-life care, the genetics of sepsis, and most recently the field of systems biology and its application to critical care and clinical medicine.
Publications
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Effect of Monetary Incentives on Peer Review Acceptance and Completion: A Quasi-Randomized Interventional Trial.
Crit Care Med
03/06/2025 Authors: Cotton CS; Alam A; Tosta S; Buchman TG; Maslove DM -
PREDICTING SEPSIS-INDUCED HYPOTENSION PATIENT ATTRIBUTES FOR RESTRICTIVE VERSUS LIBERAL FLUID STRATEGY.
Shock Volume: 63 Page(s): 399 - 405
03/01/2025 Authors: Upadhyaya P; Wang J; Mathew DT; Ali A; Tallowin S; Gann E; Lisboa FA; Schobel SA; Elster EA; Buchman TG -
Tomorrow Was Yesterday: A Farewell Note from the Editor.
Crit Care Med Volume: 52 Page(s): 1813 - 1815
12/01/2024 Authors: Buchman TG -
Derivation and validation of generalized sepsis-induced acute respiratory failure phenotypes among critically ill patients: a retrospective study.
Crit Care Volume: 28 Page(s): 321
10/01/2024 Authors: Choudhary T; Upadhyaya P; Davis CM; Yang P; Tallowin S; Lisboa FA; Schobel SA; Coopersmith CM; Elster EA; Buchman TG -
Parsimonious Waveform-derived Features consisting of Pulse Arrival Time and Heart Rate Variability Predicts the Onset of Septic Shock.
Biomed Signal Process Control Volume: 92
06/01/2024 Authors: Soliman MM; Marshall C; Kimball JP; Choudhary T; Clermont G; Pinsky MR; Buchman TG; Coopersmith CM; Inan OT; Kamaleswaran R -
Derivation and Validation of Generalized Sepsis-induced Acute Respiratory Failure Phenotypes Among Critically Ill Patients: A Retrospective Study.
Res Sq
04/30/2024 Authors: Choudhary T; Upadhyaya P; Davis CM; Yang P; Tallowin S; Lisboa FA; Schobel SA; Coopersmith CM; Elster EA; Buchman TG -
Preparing better: Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV) therapeutics trials lessons learned: A call to the future.
J Clin Transl Sci Volume: 8 Page(s): e150
01/01/2024 Authors: Adam SJ; Buchman TG; Currier JS; Draghia-Akli R; Fessel JP; Higgs ES; Hughes EA; LaVange L; Menetski JP; Read SW -
ClotCatcher: a novel natural language model to accurately adjudicate venous thromboembolism from radiology reports.
BMC Med Inform Decis Mak Volume: 23 Page(s): 262
11/16/2023 Authors: Wang J; de Vale JS; Gupta S; Upadhyaya P; Lisboa FA; Schobel SA; Elster EA; Dente CJ; Buchman TG; Kamaleswaran R -
The Reviewer Academy of the Society of Critical Care Medicine: Key Principles and Strategic Plan.
Crit Care Med Volume: 51 Page(s): 1111 - 1123
09/01/2023 Authors: Alexander PMA; Aslakson RA; Barreto EF; Lee JH; Meissen H; Morrow BM; Nazer L; Branson RD; Mayer KP; Napolitano N -
Error, Fraud, and Responsibility.
Crit Care Med Volume: 51 Page(s): 1105 - 1107
09/01/2023 Authors: Buchman TG; Bleck TP; Busl KM; Dellinger RP; Deutschman CS; Kadri SS; Marshall JC; Maslove DM; Masur H; Osborn TM -
A random forest model using flow cytometry data identifies pulmonary infection after thoracic injury.
J Trauma Acute Care Surg Volume: 95 Page(s): 39 - 46
07/01/2023 Authors: Gelbard RB; Hensman H; Schobel S; Stempora L; Gann E; Moris D; Dente CJ; Buchman TG; Kirk AD; Elster E -
Astegolimab or Efmarodocokin Alfa in Patients With Severe COVID-19 Pneumonia: A Randomized, Phase 2 Trial.
Crit Care Med Volume: 51 Page(s): 103 - 116
01/01/2023 Authors: Waters M; McKinnell JA; Kalil AC; Martin GS; Buchman TG; Theess W; Yang X; Lekkerkerker AN; Staton T; Rosenberger CM -
Fifty Years of Critical Care Medicine: The Editors' Perspective.
Crit Care Med Volume: 51 Page(s): 2 - 10
01/01/2023 Authors: Buchman TG; Chernow B; Kochanek PM; Parrillo JE -
Fifty Years of Critical Care Medicine.
Crit Care Med Volume: 51 Page(s): 1
01/01/2023 Authors: Buchman TG; Editor-in-Chief -
Cellular microRNAs correlate with clinical parameters in multiple injury patients.
J Trauma Acute Care Surg Volume: 93 Page(s): 427 - 438
10/01/2022 Authors: Vicente DA; Schobel SA; Anfossi S; Hensman H; Lisboa F; Robertson H; Khatri V; Bradley MJ; Shimizu M; Buchman TG -
The authors reply.
Crit Care Med Volume: 50 Page(s): e604 - e606
06/01/2022 Authors: Bleck TP; Buchman TG; Chang CWJ; Dellinger RP; Deutschman CS; Kadri SS; Marshall JC; Maslove DM; Masur H; Osborn TM -
Redefining critical illness.
Nat Med Volume: 28 Page(s): 1141 - 1148
06/01/2022 Authors: Maslove DM; Tang B; Shankar-Hari M; Lawler PR; Angus DC; Baillie JK; Baron RM; Bauer M; Buchman TG; Calfee CS -
The Coronavirus Disease 2019 Pandemic Impacts Burnout Syndrome Differently Among Multiprofessional Critical Care Clinicians-A Longitudinal Survey Study.
Crit Care Med Volume: 50 Page(s): 440 - 448
03/01/2022 Authors: Moll V; Meissen H; Pappas S; Xu K; Rimawi R; Buchman TG; Fisher L; Bakshi V; Zellinger M; Coopersmith CM -
Viral Micro-RNAs Are Detected in the Early Systemic Response to Injury and Are Associated With Outcomes in Polytrauma Patients.
Crit Care Med Volume: 50 Page(s): 296 - 306
02/01/2022 Authors: Vicente D; Schobel SA; Anfossi S; Hensman H; Lisboa F; Robertson H; Khatri V; Bradley MJ; Shimizu M; Buchman TG -
Regionalization of Critical Care in the United States: Current State and Proposed Framework From the Academic Leaders in Critical Care Medicine Task Force of the Society of Critical Care Medicine.
Crit Care Med Volume: 50 Page(s): 37 - 49
01/01/2022 Authors: Leung S; Pastores SM; Oropello JM; Lilly CM; Galvagno SM; Badjatia N; Jacobi J; Herr DL; Oliveira JD; Academic Leaders in Critical Care Medicine Task Force of the Society of Critical Care Medicine -
Physician and Trainee Perceptions of Telecritical Care Practice and Education: Results of a Programmatic Survey.
Telemed Rep Volume: 3 Page(s): 201 - 205
01/01/2022 Authors: Sharifpour M; Buchman T; Hiddleson C; Jabaley CS; Raikhelkar J -
Seasonal influenza vaccination is associated with reduced risk of death among Medicare beneficiaries.
Vaccine Volume: 39 Page(s): 7569 - 7577
12/20/2021 Authors: Buchman TG; Simpson SQ; Sciarretta KL; Finne KP; Sowers N; Collier M; Chavan S; Do R; Lin C; Oke I -
A Locally Optimized Data-Driven Tool to Predict Sepsis-Associated Vasopressor Use in the ICU.
Crit Care Med Volume: 49 Page(s): e1196 - e1205
12/01/2021 Authors: Holder AL; Shashikumar SP; Wardi G; Buchman TG; Nemati S -
Sepsis Among Medicare Beneficiaries: 4. Precoronavirus Disease 2019 Update January 2012-February 2020.
Crit Care Med Volume: 49 Page(s): 2058 - 2069
12/01/2021 Authors: Frank CE; Buchman TG; Simpson SQ; Sciarretta KL; Plopper GE; Finne KP; Sowers N; Collier M; Chavan S; Lin C -
Altered Heart Rate Variability Early in ICU Admission Differentiates Critically Ill Coronavirus Disease 2019 and All-Cause Sepsis Patients.
Crit Care Explor Volume: 3 Page(s): e0570
12/01/2021 Authors: Kamaleswaran R; Sadan O; Kandiah P; Li Q; Coopersmith CM; Buchman TG -
Prediction of venous thromboembolism using clinical and serum biomarker data from a military cohort of trauma patients.
BMJ Mil Health Volume: 167 Page(s): 402 - 407
12/01/2021 Authors: Bradley M; Shi A; Khatri V; Schobel S; Silvius E; Kirk A; Buchman T; Oh J; Elster E -
Analysis of Discrepancies Between Pulse Oximetry and Arterial Oxygen Saturation Measurements by Race and Ethnicity and Association With Organ Dysfunction and Mortality.
JAMA Netw Open Volume: 4 Page(s): e2131674
11/01/2021 Authors: Wong A-KI; Charpignon M; Kim H; Josef C; de Hond AAH; Fojas JJ; Tabaie A; Liu X; Mireles-Cabodevila E; Carvalho L -
Accelerating Coronavirus Disease 2019 Therapeutic Interventions and Vaccines-Selecting Compounds for Clinical Evaluation in Coronavirus Disease 2019 Clinical Trials.
Crit Care Med Volume: 49 Page(s): 1963 - 1973
11/01/2021 Authors: Buchman TG; Draghia-Akli R; Adam SJ; Aggarwal NR; Fessel JP; Higgs ES; Menetski JP; Read SW; Hughes EA; Accelerating Coronavirus Disease 2019 Therapeutic Interventions and Vaccines (ACTIV) Therapeutics Clinical Working Group -
Predicting the need for massive transfusion: Prospective validation of a smartphone-based clinical decision support tool.
Surgery Volume: 170 Page(s): 1574 - 1580
11/01/2021 Authors: Dente CJ; Mina MJ; Morse BC; Hensman H; Schobel S; Gelbard RB; Belard A; Buchman TG; Kirk AD; Elster EA -
Disparities in Sepsis Outcomes May Be Attributable to Access to Care.
Crit Care Med Volume: 49 Page(s): 1358 - 1360
08/01/2021 Authors: Plopper GE; Sciarretta KL; Buchman TG -
An integrative model using flow cytometry identifies nosocomial infection after trauma.
J Trauma Acute Care Surg Volume: 91 Page(s): 47 - 53
07/01/2021 Authors: Gelbard RB; Hensman H; Schobel S; Stempora LL; Moris D; Dente CJ; Buchman TG; Kirk AD; Elster E -
Prediction of Acute Respiratory Failure Requiring Advanced Respiratory Support in Advance of Interventions and Treatment: A Multivariable Prediction Model From Electronic Medical Record Data.
Crit Care Explor Volume: 3 Page(s): e0402
05/01/2021 Authors: Wong A-KI; Kamaleswaran R; Tabaie A; Reyna MA; Josef C; Robichaux C; de Hond AAH; Steyerberg EW; Holder AL; Nemati S -
Effect of Vitamin C, Thiamine, and Hydrocortisone on Ventilator- and Vasopressor-Free Days in Patients With Sepsis: The VICTAS Randomized Clinical Trial.
JAMA Volume: 325 Page(s): 742 - 750
02/23/2021 Authors: Sevransky JE; Rothman RE; Hager DN; Bernard GR; Brown SM; Buchman TG; Busse LW; Coopersmith CM; DeWilde C; Ely EW -
A Celebration of the Society of Critical Care Medicine at the Half-Century Mark.
Crit Care Med Volume: 49 Page(s): 167 - 168
02/01/2021 Authors: Buchman TG -
Clinical risk factors and inflammatory biomarkers of post-traumatic acute kidney injury in combat patients.
Surgery Volume: 168 Page(s): 662 - 670
10/01/2020 Authors: Muoz B; Schobel SA; Lisboa FA; Khatri V; Grey SF; Dente CJ; Kirk AD; Buchman T; Elster EA -
Pandemic-Related Submissions: The Challenge of Discerning Signal Amidst Noise.
Crit Care Med Volume: 48 Page(s): 1099 - 1102
08/01/2020 Authors: Bleck TP; Buchman TG; Dellinger RP; Deutschman CS; Marshall JC; Maslove DM; Masur H; Parker MM; Prough DS; Sarwal A -
Critical care journals during the COVID-19 pandemic: challenges and responsibilities.
Intensive Care Med Volume: 46 Page(s): 1521 - 1523
08/01/2020 Authors: Citerio G; Bakker J; Brochard L; Buchman TG; Jaber S; Mazzone PJ; Teboul J-L; Vincent J-L; Azoulay E -
Advanced Modeling to Predict Pneumonia in Combat Trauma Patients.
World J Surg Volume: 44 Page(s): 2255 - 2262
07/01/2020 Authors: Bradley M; Dente C; Khatri V; Schobel S; Lisboa F; Shi A; Hensman H; Kirk A; Buchman TG; Elster E -
Correction to: Advanced Modeling to Predict Pneumonia in Combat Trauma Patients.
World J Surg Volume: 44 Page(s): 2263
07/01/2020 Authors: Bradley M; Dente C; Khatri V; Schobel S; Lisboa F; Shi A; Hensman H; Kirk A; Buchman TG; Elster E -
Pandemic-Related Submissions: The Challenge of Discerning Signal Amidst Noise.
Crit Care Med
06/11/2020 Authors: Kaplan LJ; Bleck TP; Buchman TG; Dellinger RP; Deutschman CS; Marshall JC; Maslove DM; Masur H; Parker MM; Prough DS -
Driving biology: The effect of standardized wound management on wound biomarker profiles.
J Trauma Acute Care Surg Volume: 88 Page(s): 379 - 389
03/01/2020 Authors: Dente CJ; Styrmisdottir E; Shi A; Schobel S; Khatri V; Potter BK; Forsberg JA; Buchman T; Kirk AD; Elster E -
Sepsis Among Medicare Beneficiaries: 3. The Methods, Models, and Forecasts of Sepsis, 2012-2018.
Crit Care Med Volume: 48 Page(s): 302 - 318
03/01/2020 Authors: Buchman TG; Simpson SQ; Sciarretta KL; Finne KP; Sowers N; Collier M; Chavan S; Oke I; Pennini ME; Santhosh A -
Sepsis Among Medicare Beneficiaries: 2. The Trajectories of Sepsis, 2012-2018.
Crit Care Med Volume: 48 Page(s): 289 - 301
03/01/2020 Authors: Buchman TG; Simpson SQ; Sciarretta KL; Finne KP; Sowers N; Collier M; Chavan S; Oke I; Pennini ME; Santhosh A -
Sepsis Among Medicare Beneficiaries: 1. The Burdens of Sepsis, 2012-2018.
Crit Care Med Volume: 48 Page(s): 276 - 288
03/01/2020 Authors: Buchman TG; Simpson SQ; Sciarretta KL; Finne KP; Sowers N; Collier M; Chavan S; Oke I; Pennini ME; Santhosh A -
Exploring the Epigenetics of Severe Sepsis: First Step in a Long Journey.
Crit Care Med Volume: 48 Page(s): 254 - 255
02/01/2020 Authors: Buchman TG; Zehnbauer BA -
Classification of Subsequent Acute Respiratory Failure (ARF) Requiring Prolonged Mechanical Ventilation by Basic Machine Learning Algorithms
Volume: 201
01/01/2020 Authors: Wong AI; Tabaie A; Holder AL; Reyna MA; Josef C; Robichaux C; Nemati S; Buchman T; Blum JM -
Random forest modeling can predict infectious complications following trauma laparotomy.
J Trauma Acute Care Surg Volume: 87 Page(s): 1125 - 1132
11/01/2019 Authors: Gelbard RB; Hensman H; Schobel S; Khatri V; Tracy BM; Dente CJ; Buchman T; Kirk A; Elster E -
Intensive Care Unit Telemedicine: Innovations and Limitations.
Crit Care Clin Volume: 35 Page(s): 497 - 509
07/01/2019 Authors: Bender W; Hiddleson CA; Buchman TG -
BARDA'S SOLVING SEPSIS PROGRAM
Volume: 51 Page(s): 11 - 11
06/01/2019 Authors: Buchman TG -
AN INNOVATIVE, BLENDED, PROJECT-BASED HEALTH INFORMATICS COURSE
Page(s): 97 - 125
01/01/2019 Authors: Braunstein ML; Hiddleson C; Buchman TG; Ghassemi MM; Nemati S; Braun P; Goodman AB -
Control of Confounding and Reporting of Results in Causal Inference Studies. Guidance for Authors from Editors of Respiratory, Sleep, and Critical Care Journals.
Ann Am Thorac Soc Volume: 16 Page(s): 22 - 28
01/01/2019 Authors: Lederer DJ; Bell SC; Branson RD; Chalmers JD; Marshall R; Maslove DM; Ost DE; Punjabi NM; Schatz M; Smyth AR -
Quantifying resilience of humans and other animals.
Proc Natl Acad Sci U S A Volume: 115 Page(s): 11883 - 11890
11/20/2018 Authors: Scheffer M; Bolhuis JE; Borsboom D; Buchman TG; Gijzel SMW; Goulson D; Kammenga JE; Kemp B; van de Leemput IA; Levin S -
The Impact of Enhanced Critical Care Training and 24/7 (Tele-ICU) Support on Medicare Spending and Postdischarge Utilization Patterns.
Health Serv Res Volume: 53 Page(s): 2099 - 2117
08/01/2018 Authors: Trombley MJ; Hassol A; Lloyd JT; Buchman TG; Marier AF; White A; Colligan E -
Battlefield to Bedside: Bringing Precision Medicine to Surgical Care.
J Am Coll Surg Volume: 226 Page(s): 1093 - 1102
06/01/2018 Authors: Belard A; Schobel S; Bradley M; Potter BK; Dente C; Buchman T; Kirk A; Elster E -
An Interpretable Machine Learning Model for Accurate Prediction of Sepsis in the ICU.
Crit Care Med Volume: 46 Page(s): 547 - 553
04/01/2018 Authors: Nemati S; Holder A; Razmi F; Stanley MD; Clifford GD; Buchman TG -
Critical Care Organizations: Building and Integrating Academic Programs.
Crit Care Med Volume: 46 Page(s): e334 - e341
04/01/2018 Authors: Moore JE; Oropello JM; Stoltzfus D; Masur H; Coopersmith CM; Nates J; Doig C; Christman J; Hite RD; Angus DC -
The Uniformed Services University's Surgical Critical Care Initiative (SC2i): Bringing Precision Medicine to the Critically Ill.
Mil Med Volume: 183 Page(s): 487 - 495
03/01/2018 Authors: Belard A; Buchman T; Dente CJ; Potter BK; Kirk A; Elster E -
Pharmacogenomic biomarkers do not predict response to drotrecogin alfa in patients with severe sepsis.
Ann Intensive Care Volume: 8 Page(s): 16
01/31/2018 Authors: Annane D; Mira J-P; Ware LB; Gordon AC; Hinds CJ; Christiani DC; Sevransky J; Barnes K; Buchman TG; Heagerty PJ -
Serial Daily Organ Failure Assessment Beyond ICU Day 5 Does Not Independently Add Precision to ICU Risk-of-Death Prediction.
Crit Care Med Volume: 45 Page(s): 2014 - 2022
12/01/2017 Authors: Holder AL; Overton E; Lyu P; Kempker JA; Nemati S; Razmi F; Martin GS; Buchman TG; Murphy DJ -
Towards precision medicine: Accurate predictive modeling of infectious complications in combat casualties.
J Trauma Acute Care Surg Volume: 83 Page(s): 609 - 616
10/01/2017 Authors: Dente CJ; Bradley M; Schobel S; Gaucher B; Buchman T; Kirk AD; Elster E -
Filtering authentic sepsis arising in the ICU using administrative codes coupled to a SIRS screening protocol.
J Crit Care Volume: 39 Page(s): 220 - 224
06/01/2017 Authors: Sudduth CL; Overton EC; Lyu PF; Rimawi RH; Buchman TG -
Patient- and Family-Centered Care: First Steps on a Long Journey.
Crit Care Med Volume: 45 Page(s): 757 - 758
05/01/2017 Authors: Sevransky JE; Nicholl B; Nicholl J-B; Buchman TG -
Precision diagnosis: a view of the clinical decision support systems (CDSS) landscape through the lens of critical care.
J Clin Monit Comput Volume: 31 Page(s): 261 - 271
04/01/2017 Authors: Belard A; Buchman T; Forsberg J; Potter BK; Dente CJ; Kirk A; Elster E -
Practice Guidelines as Implementation Science: The Journal Editors' Perspective.
Crit Care Med Volume: 45 Page(s): 553 - 554
03/01/2017 Authors: Buchman TG; Azoulay E -
Practice guidelines as implementation science: the journal editors' perspective.
Intensive Care Med Volume: 43 Page(s): 378 - 379
03/01/2017 Authors: Buchman TG; Azoulay E -
Editorial Comment.
Volume: 197 Page(s): 844
03/01/2017 Authors: Wong KK -
Innovative Interdisciplinary Strategies to Address the Intensivist Shortage.
Crit Care Med Volume: 45 Page(s): 298 - 304
02/01/2017 Authors: Buchman TG; Coopersmith CM; Meissen HW; Grabenkort WR; Bakshi V; Hiddleson CA; Gregg SR -
Promoting Patient- and Family-Centered Care in the Intensive Care Unit: A Dissemination Project.
AACN Adv Crit Care Volume: 28 Page(s): 155 - 159
01/01/2017 Authors: Kleinpell R; Buchman TG; Harmon L; Nielsen M -
ORGAN FAILURE DATA OVER TIME IN THE CRITICALLY ILL: AT WHAT COST, AND TO WHAT BENEFIT?
Volume: 44
12/01/2016 Authors: Holder A; Murphy D; Overton E; Lyu P; Martin G; Buchman T -
A Glimpse of Precision Medicine for Multiple-Organ Dysfunction Syndrome.
Crit Care Med Volume: 44 Page(s): 2121 - 2122
11/01/2016 Authors: Buchman TG -
Precision Medicine for Critical Illness and Injury.
Crit Care Med Volume: 44 Page(s): 1635 - 1638
09/01/2016 Authors: Buchman TG; Billiar TR; Elster E; Kirk AD; Rimawi RH; Vodovotz Y; Zehnbauer BA -
Impact of a Sequential Intervention on Albumin Utilization in Critical Care.
Crit Care Med Volume: 44 Page(s): 1307 - 1313
07/01/2016 Authors: Lyu PF; Hockenberry JM; Gaydos LM; Howard DH; Buchman TG; Murphy DJ -
Slowing Down of Recovery as Generic Risk Marker for Acute Severity Transitions in Chronic Diseases.
Crit Care Med Volume: 44 Page(s): 601 - 606
03/01/2016 Authors: Olde Rikkert MGM; Dakos V; Buchman TG; Boer RD; Glass L; Cramer AOJ; Levin S; van Nes E; Sugihara G; Ferrari MD -
Mitchell P. Fink, Associate Editor: A Remembrance.
Crit Care Med Volume: 44 Page(s): 253
02/01/2016 Authors: Buchman TG -
Long-term survival following in-hospital cardiac arrest: A matched cohort study.
Resuscitation Volume: 99 Page(s): 72 - 78
02/01/2016 Authors: Feingold P; Mina MJ; Burke RM; Hashimoto B; Gregg S; Martin GS; Leeper K; Buchman T -
Using Incentives to Improve Resource Utilization: A Quasi-Experimental Evaluation of an ICU Quality Improvement Program.
Crit Care Med Volume: 44 Page(s): 162 - 170
01/01/2016 Authors: Murphy DJ; Lyu PF; Gregg SR; Martin GS; Hockenberry JM; Coopersmith CM; Sterling M; Buchman TG; Sevransky J -
Precision Diagnosis Is a Team Sport.
Crit Care Med Volume: 44 Page(s): 229 - 230
01/01/2016 Authors: Zehnbauer BA; Buchman TG -
Precision Diagnosis Is a Team Sport.
J Mol Diagn Volume: 18 Page(s): 1 - 2
01/01/2016 Authors: Zehnbauer BA; Buchman TG -
Prevalence and Impact of Unknown Diabetes in the ICU.
Crit Care Med Volume: 43 Page(s): e541 - e550
12/01/2015 Authors: Carpenter DL; Gregg SR; Xu K; Buchman TG; Coopersmith CM -
Policies, Populations, Practices, Providersand a Patient.
Crit Care Med Volume: 43 Page(s): 2273 - 2274
11/01/2015 Authors: Buchman TG -
Effectiveness of Minocycline and Rifampin vs Chlorhexidine and Silver Sulfadiazine-Impregnated Central Venous Catheters in Preventing Central Line-Associated Bloodstream Infection in a High-Volume Academic Intensive Care Unit: A Before and after Trial.
J Am Coll Surg Volume: 221 Page(s): 739 - 747
09/01/2015 Authors: Bonne S; Mazuski JE; Sona C; Schallom M; Boyle W; Buchman TG; Bochicchio GV; Coopersmith CM; Schuerer DJE -
The workforce crisis: a functioning solution.
Am J Respir Crit Care Med Volume: 191 Page(s): 1340 - 1341
06/01/2015 Authors: Buchman T; Grabenkort R; Coopersmith C; Meissen H; Gregg S -
You tell me.
Crit Care Med Volume: 43 Page(s): 727 - 728
04/01/2015 Authors: Buchman TG -
Practical science and the science of practice: Critical Care Medicine, 2015.
Crit Care Med Volume: 43 Page(s): 259 - 260
02/01/2015 Authors: Buchman TG -
Joseph E. Parrillo, MD, MCCM: Editor-in-Chief, 1997-2014: an appreciation.
Crit Care Med Volume: 43 Page(s): 1 - 2
01/01/2015 Authors: Buchman TG -
DYNAMICAL DENSITY PLOTS FOR THE DISPLAY OF RESPIRATORY PATTERNS DURING A SPONTANEOUS BREATHING TRIAL
CRITICAL CARE MEDICINE Volume: 42
12/01/2014 Authors: Hopkins M; Buchman T -
ASSESSING KNOWLEDGE AND CONFIDENCE OF THE NURSE PRACTITIONER AND PHYSICIAN ASSISTANT RESIDENT
CRITICAL CARE MEDICINE Volume: 42
12/01/2014 Authors: Meissen H; Carpenter D; Grabenkort R; Buchman T; Coopersmith C -
Reduced red blood cell transfusion in cardiothoracic surgery after implementation of a novel clinical decision support tool.
J Am Coll Surg Volume: 219 Page(s): 1028 - 1036
11/01/2014 Authors: Razavi SA; Carter AB; Puskas JD; Gregg SR; Aziz IF; Buchman TG -
Multi-scale symbolic entropy analysis provides prognostic prediction in patients receiving extracorporeal life support.
Crit Care Volume: 18 Page(s): 548
10/24/2014 Authors: Lin Y-H; Huang H-C; Chang Y-C; Lin C; Lo M-T; Liu L-YD; Tsai P-R; Chen Y-S; Ko W-J; Ho Y-L -
Comparing the information seeking strategies of residents, nurse practitioners, and physician assistants in critical care settings.
J Am Med Inform Assoc Volume: 21 Page(s): e249 - e256
10/01/2014 Authors: Kannampallil TG; Jones LK; Patel VL; Buchman TG; Franklin A -
Packed red blood cell transfusion practices in cardiothoracic surgery before and after the implementation of transfusion clinical decision support
Volume: 219 Page(s): E153 - E154
10/01/2014 Authors: Razavi SA; Carter AB; Puskas JD; Gregg SR; Aziz IF; Buchman TG -
Correction of endocrinopathy rescues chronic critically ill surgical patients
Volume: 219 Page(s): E29 - E29
10/01/2014 Authors: Razavi SA; Ward CT; Taylor BE; Buchman TG -
Cardiovascular variability as a measure of inflammation*.
Crit Care Med Volume: 42 Page(s): 1964
08/01/2014 Authors: Buchman TG -
From data patterns to biological mechanism in critical illness: the role of engineering.
J Crit Care Volume: 29 Page(s): 668
08/01/2014 Authors: Buchman TG -
Feasibility and economic impact of dedicated hospice inpatient units for terminally ill ICU patients.
Crit Care Med Volume: 42 Page(s): 1074 - 1080
05/01/2014 Authors: Binney ZO; Quest TE; Feingold PL; Buchman T; Majesko AA -
In-hospital mortality after cardiac surgery: patient characteristics, timing, and association with postoperative length of intensive care unit and hospital stay.
Ann Thorac Surg Volume: 97 Page(s): 1220 - 1225
04/01/2014 Authors: Mazzeffi M; Zivot J; Buchman T; Halkos M -
Comparison of circuit patency and exchange rates between 2 different continuous renal replacement therapy machines.
J Crit Care Volume: 29 Page(s): 272 - 277
04/01/2014 Authors: Razavi SA; Still MD; White SJ; Buchman TG; Connor MJ -
Health Professionals in Critical Care
Volume: 18 Page(s): 41 - 51
01/01/2014 Authors: Buchman TG -
The Effects of Structuring Clinical Rounds on Communication and Efficiency
Page(s): 409 - 420
01/01/2014 Authors: Jones LK; Franklin A; Kannampallil TG; Buchman TG -
Sub-optimal Patterns of Information Use: A Rational Analysis of Information Seeking Behavior in Critical Care
Page(s): 389 - 408
01/01/2014 Authors: Kannampallil TG; Franklin A; Cohen T; Buchman TG -
Large Scale Cognitive Error in Critical Care: The Adoption of "Best Practices" That Are Either Ineffective or Harm Patients
Page(s): 441 - 454
01/01/2014 Authors: Buchman TG -
Prescribing patterns of hydrocortisone in septic shock: a single-center experience of how surviving sepsis guidelines are interpreted and translated into bedside practice.
Crit Care Med Volume: 41 Page(s): 2310 - 2317
10/01/2013 Authors: Contrael KM; Killian AJ; Gregg SR; Buchman TG; Coopersmith CM -
Social Norms and Global Environmental Challenges: The Complex Interaction of Behaviors, Values, and Policy.
Bioscience Volume: 63 Page(s): 164 - 175
03/01/2013 Authors: Kinzig AP; Ehrlich PR; Alston LJ; Arrow K; Barrett S; Buchman TG; Daily GC; Levin B; Levin S; Oppenheimer M -
The turn team: a novel strategy for reducing pressure ulcers in the surgical intensive care unit.
J Am Coll Surg Volume: 216 Page(s): 373 - 379
03/01/2013 Authors: Still MD; Cross LC; Dunlap M; Rencher R; Larkins ER; Carpenter DL; Buchman TG; Coopersmith CM -
Prediction of heart rate response to conclusion of the spontaneous breathing trial by fluctuation dissipation theory.
Phys Biol Volume: 10 Page(s): 016006
02/01/2013 Authors: Chen M; Niestemski LR; Prevost R; McRae M; Cholleti S; Najarro G; Buchman TG; Deem MW -
Priority queuing models for hospital intensive care units and impacts to severe case patients.
AMIA Annu Symp Proc Volume: 2013 Page(s): 841 - 850
01/01/2013 Authors: Hagen MS; Jopling JK; Buchman TG; Lee EK -
Informal contracts, shared decision making, and the covenant of care.
Crit Care Med Volume: 41 Page(s): 326 - 327
01/01/2013 Authors: Buchman TG -
ASSOCIATION AMONG INITIAL CENTRAL VENOUS OXYGEN SATURATION LEVELS, INITIAL BLOOD LACTATE LEVELS AND OUTCOME IN SEPTIC PATIENTS TREATED WITH EARLY GOAL-DIRECTED THERAPY
Volume: 40 Page(s): U174 - U174
12/01/2012 Authors: Nakamura M; Coopersmith C; Greg M; McConnell K; Kandiah P; Still M; Nicholls M; Oda S; Hirasawa H; Buchman T -
DIFFERENCE IN LACTATE LEVELS AND CARDIAC FUNCTION AMONG THREE SEPTIC PATIENT GROUPS STRATIFIED BY INITIAL CENTRAL VENOUS OXYGEN SATURATION LEVELS
Volume: 40 Page(s): U279 - U279
12/01/2012 Authors: Nakamura M; Coopersmith C; Greg M; Kandiah P; McConnell K; Still M; Nicholls M; Oda S; Hirasawa H; Buchman T -
UNDOCUMENTED HYPOTENSION EVENTS IN UNIVERSITY ICUS
Volume: 40 Page(s): U225 - U225
12/01/2012 Authors: Najarro G; Cholleti S; Buchman T -
THE IMPACT OF UNKNOWN DIABETES IN THE ICU
Volume: 40 Page(s): U89 - U89
12/01/2012 Authors: Carpenter D; Gregg S; Buchman T; Coopersmith C -
COMPARISON OF SELF-DESCRIBED AND ACTUAL PRESCRIBING PATTERNS OF HYDROCORTISONE IN SEPTIC SHOCK IN AN ACADEMIC MEDICAL CENTER
Volume: 40 Page(s): U293 - U293
12/01/2012 Authors: Killian A; Contrael K; Gregg S; Buchman T; Coopersmith C -
EFFECTS OF HEMOGLOBIN A1C ON GLYCEMIC CONTROL IN THE ICU
Volume: 40 Page(s): U91 - U91
12/01/2012 Authors: Carpenter D; Gregg S; Buchman T; Coopersmith C -
PRESCRIBING PATTERNS OF INTRAVENOUS HYDROCORTISONE IN SEPTIC SHOCK: FINDINGS FROM AN ACADEMIC HEALTHCARE SYSTEM
Volume: 40 Page(s): U135 - U136
12/01/2012 Authors: Contrael K; Killian A; Gregg S; Buchman T; Coopersmith C -
THE IMPACT OF INTENSIVIST PRESENCE ON MULTIDISCIPLINARY ROUNDS IN INTENSIVE CARE UNITS
Volume: 40 Page(s): U223 - U224
12/01/2012 Authors: Mieczkowski B; Ali N; McCann E; Buchman T; Farmer J; Gorman M; Lilly C; Rainey T -
Fractals in clinical hemodynamics.
Anesthesiology Volume: 117 Page(s): 699 - 700
10/01/2012 Authors: Buchman TG -
Tumor necrosis factor -308 polymorphism (rs1800629) is associated with mortality and ventilator duration in 1057 Caucasian patients.
Cytokine Volume: 60 Page(s): 249 - 256
10/01/2012 Authors: Watanabe E; Zehnbauer BA; Oda S; Sato Y; Hirasawa H; Buchman TG -
Shock supports the use of animal research reporting guidelines.
Shock Volume: 38 Page(s): 1 - 3
07/01/2012 Authors: Reynolds P; Wall P; van Griensven M; McConnell K; Lang C; Buchman T -
Extra credit*.
Crit Care Med Volume: 40 Page(s): 1028 - 1029
03/01/2012 Authors: Buchman TG -
Patient-care time allocation by nurse practitioners and physician assistants in the intensive care unit.
Crit Care Volume: 16 Page(s): R27
02/15/2012 Authors: Carpenter DL; Gregg SR; Owens DS; Buchman TG; Coopersmith CM -
Energy deficit and length of hospital stay can be reduced by a two-step quality improvement of nutrition therapy: the intensive care unit dietitian can make the difference.
Crit Care Med Volume: 40 Page(s): 662 - 663
02/01/2012 Authors: Buchman TG -
Sepsis through the eyes of an engineer -- why treatments have succeeded and failed.
Crit Rev Biomed Eng Volume: 40 Page(s): 353 - 361
01/01/2012 Authors: Jopling J; Buchman TG -
Postreperfusion cardiac arrest and resuscitation during orthotopic liver transplantation: dynamic visualization and analysis of physiologic recordings.
Shock Volume: 37 Page(s): 34 - 38
01/01/2012 Authors: Vannucci A; Burykin A; Krejci V; Peck T; Buchman TG; Kangrga IM -
The price of a miracle.
J Am Coll Surg Volume: 214 Page(s): 25 - 26
01/01/2012 Authors: Buchman TG -
HEAVY WATER MITIGATES SURVIVAL IN SEPTIC MICE
Volume: 37 Page(s): 62 - 62
01/01/2012 Authors: Breed ER; Liang Z; Wagener ME; Yoseph BP; Ferrer IR; Ford ML; Buchman TG; Coopersmith CM -
Using "off-the-shelf" tools for terabyte-scale waveform recording in intensive care: computer system design, database description and lessons learned.
Comput Methods Programs Biomed Volume: 103 Page(s): 151 - 160
09/01/2011 Authors: Burykin A; Peck T; Buchman TG -
Proceedings from the Montebello Round Table Discussion. Second annual conference on Complexity and Variability discusses research that brings innovation to the bedside.
J Crit Care Volume: 26 Page(s): 325 - 327
06/01/2011 Authors: Seely AJE; Kauffman SA; Bates JHT; Macklem PT; Suki B; Marshall JC; Batchinsky AI; Perez-Velazquez JL; Seiver A; McGregor C -
Modules, modularity and adaptation: Comment on "The emergence of modularity in biological systems" by Dirk M. Lorenz, Alice Jeng, Michael W. Deem.
Phys Life Rev Volume: 8 Page(s): 163 - 164
06/01/2011 Authors: Buchman TG -
Recovery at the edge of error: debunking the myth of the infallible expert.
J Biomed Inform Volume: 44 Page(s): 413 - 424
06/01/2011 Authors: Patel VL; Cohen T; Murarka T; Olsen J; Kagita S; Myneni S; Buchman T; Ghaemmaghami V -
Biomedical complexity and error.
J Biomed Inform Volume: 44 Page(s): 387 - 389
06/01/2011 Authors: Patel VL; Kahol K; Buchman T -
HEAVY WATER (D2O) SENSITIZES MICE TO CECAL LIGATION AND PUNCTURE (CLP)
Volume: 35 Page(s): 70 - 70
06/01/2011 Authors: Liang Z; Breed ER; Buchman TG; Coopersmith CM -
METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS AND PSEUDOMONAS AERUGINOSA PNEUMONIA INDUCE INTESTINAL EPITHELIAL APOPTOSIS VIA DISTINCT MECHANISMS
Volume: 35 Page(s): 66 - 67
06/01/2011 Authors: Breed ER; Jung E; Liang Z; Perrone EE; Dominguez JA; Dunne WM; Burd EM; Buchman TG; Coopersmith CM -
Targeted temperature management in critical care: a report and recommendations from five professional societies.
Crit Care Med Volume: 39 Page(s): 1113 - 1125
05/01/2011 Authors: Nunnally ME; Jaeschke R; Bellingan GJ; Lacroix J; Mourvillier B; Rodriguez-Vega GM; Rubertsson S; Vassilakopoulos T; Weinert C; Zanotti-Cavazzoni S -
The role of heat shock protein 70 in mediating age-dependent mortality in sepsis.
J Immunol Volume: 186 Page(s): 3718 - 3725
03/15/2011 Authors: McConnell KW; Fox AC; Clark AT; Chang N-YN; Dominguez JA; Farris AB; Buchman TG; Hunt CR; Coopersmith CM -
Peaceful Rest vs Rest in Peace INVITED CRITIQUE
ARCHIVES OF SURGERY Volume: 146 Page(s): 278 - 279
03/01/2011 Authors: Buchman TG -
Generating Signals with Multiscale Time Irreversibility: The Asymmetric Weierstrass Function.
Complexity Volume: 16 Page(s): 29 - 38
03/01/2011 Authors: Burykin A; Costa MD; Peng C-K; Goldberger AL; Buchman TG -
Peaceful rest vs rest in peace.
Arch Surg Volume: 146 Page(s): 278 - 279
03/01/2011 Authors: Buchman TG -
Toward optimal display of physiologic status in critical care: I. Recreating bedside displays from archived physiologic data.
J Crit Care Volume: 26 Page(s): 105.e1 - 105.e9
02/01/2011 Authors: Burykin A; Peck T; Krejci V; Vannucci A; Kangrga I; Buchman TG -
INTENSIVISTS ARE MORE CONSERVATIVE THAN CT SURGEONS IN TRANSFUSING PRBCS AFTER CARDIOTHORACIC SURGERY
Volume: 38 Page(s): U77 - U77
12/01/2010 Authors: Black D; Kalwerisky R; Buchman T; Franklin A -
SEVERITY OF ANEMIA DOES NOT ACCELERATE TRANSFUSION IN CRITICAL CARE
Volume: 38 Page(s): U78 - U78
12/01/2010 Authors: Kalwerisky R; Black D; Buchman T -
IMPROVING GLYCEMIC CONTROL IN ALL INTENSIVE CARE UNITS
Volume: 38 Page(s): U219 - U219
12/01/2010 Authors: Garner K; Chang E; Milner Z; Buchman T; Stein J; Samuels O -
Half empty or half full?
Crit Care Med Volume: 38 Page(s): 1747 - 1748
08/01/2010 Authors: Batchinsky AI; Cancio LC; Buchman TG -
EFFECT OF HERITABLE AND ACQUIRED CONDITIONS ON MORTALITY OF 854 US PATIENTS WITH SEVERE SEPSIS
Volume: 33 Page(s): 7 - 7
06/01/2010 Authors: Watanabe E; Zehnbauer BA; Oda S; Shimada T; Hirasawa H; Buchman TG -
Ethical considerations in the collection of genetic data from critically ill patients: what do published studies reveal about potential directions for empirical ethics research?
Pharmacogenomics J Volume: 10 Page(s): 77 - 85
04/01/2010 Authors: Freeman BD; Kennedy CR; Frankel HL; Clarridge B; Bolcic-Jankovic D; Iverson E; Shehane E; Celious A; Zehnbauer BA; Buchman TG -
Shock: further studies with particular reference to the effects of hemorrhage. 1934.
Arch Surg Volume: 145 Page(s): 393 - 394
04/01/2010 Authors: Blalock A -
Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis.
Crit Care Med Volume: 38 Page(s): 886 - 893
03/01/2010 Authors: Fox AC; Robertson CM; Belt B; Clark AT; Chang KC; Leathersich AM; Dominguez JA; Perrone EE; Dunne WM; Hotchkiss RS -
Surgeons and their patients near the end of life.
Crit Care Med Volume: 38 Page(s): 995 - 996
03/01/2010 Authors: Buchman TG -
Novel representation of physiologic states during critical illness and recovery.
Crit Care Volume: 14 Page(s): 127
01/01/2010 Authors: Buchman TG -
Association between lymphotoxin-alpha (tumor necrosis factor-beta) intron polymorphism and predisposition to severe sepsis is modified by gender and age.
Crit Care Med Volume: 38 Page(s): 181 - 193
01/01/2010 Authors: Watanabe E; Buchman TG; Hirasawa H; Zehnbauer BA -
Streptococcus pneumoniae and Pseudomonas aeruginosa pneumonia induce distinct host responses.
Crit Care Med Volume: 38 Page(s): 223 - 241
01/01/2010 Authors: McConnell KW; McDunn JE; Clark AT; Dunne WM; Dixon DJ; Turnbull IR; Dipasco PJ; Osberghaus WF; Sherman B; Martin JR -
Examination of non-clinical factors affecting tracheostomy practice in an academic surgical intensive care unit.
Crit Care Med Volume: 37 Page(s): 3070 - 3078
12/01/2009 Authors: Freeman BD; Kennedy C; Coopersmith CM; Buchman TG -
Implementation of a mandatory checklist of protocols and objectives improves compliance with a wide range of evidence-based intensive care unit practices.
Crit Care Med Volume: 37 Page(s): 2775 - 2781
10/01/2009 Authors: Byrnes MC; Schuerer DJE; Schallom ME; Sona CS; Mazuski JE; Taylor BE; McKenzie W; Thomas JM; Emerson JS; Nemeth JL -
Enterocyte-specific epidermal growth factor prevents barrier dysfunction and improves mortality in murine peritonitis.
Am J Physiol Gastrointest Liver Physiol Volume: 297 Page(s): G471 - G479
09/01/2009 Authors: Clark JA; Gan H; Samocha AJ; Fox AC; Buchman TG; Coopersmith CM -
Predicting clinical physiology: a Markov chain model of heart rate recovery after spontaneous breathing trials in mechanically ventilated patients.
J Crit Care Volume: 24 Page(s): 347 - 361
09/01/2009 Authors: Lu Y; Burykin A; Deem MW; Buchman TG -
CD4+ lymphocytes control gut epithelial apoptosis and mediate survival in sepsis.
FASEB J Volume: 23 Page(s): 1817 - 1825
06/01/2009 Authors: Stromberg PE; Woolsey CA; Clark AT; Clark JA; Turnbull IR; McConnell KW; Chang KC; Chung C-S; Ayala A; Buchman TG -
Effects of aging on the immunopathologic response to sepsis.
Crit Care Med Volume: 37 Page(s): 1018 - 1023
03/01/2009 Authors: Turnbull IR; Clark AT; Stromberg PE; Dixon DJ; Woolsey CA; Davis CG; Hotchkiss RS; Buchman TG; Coopersmith CM -
The digital patient: predicting physiologic dynamics with mathematical models.
Crit Care Med Volume: 37 Page(s): 1167 - 1168
03/01/2009 Authors: Buchman TG -
The impact of a simple, low-cost oral care protocol on ventilator-associated pneumonia rates in a surgical intensive care unit.
J Intensive Care Med Volume: 24 Page(s): 54 - 62
01/01/2009 Authors: Sona CS; Zack JE; Schallom ME; McSweeney M; McMullen K; Thomas J; Coopersmith CM; Boyle WA; Buchman TG; Mazuski JE -
MECHANISMS OF MRSA PNEUMONIA-INDUCED GUT EPITHELIAL APOPTOSIS
Volume: 31 Page(s): 75 - 76
01/01/2009 Authors: Jung E; Perrone E; Clark J; Clark A; Dunne W; Buchman T; Hotchkiss R; Coopersmith C -
SEPSIS UNCOUPLES GUT EPITHELIAL PROLIFERATION AND DEATH FROM MIGRATION AND CELL DENSITY IN MICE
Volume: 31 Page(s): 73 - 73
01/01/2009 Authors: Clark A; Zee-Cheng B; Dunne W; Buchman T; Hotchkiss R; Coopersmith C -
Invited commentary: experience matters.
J Crit Care Volume: 23 Page(s): 556
12/01/2008 Authors: Buchman TG -
Neutrophil depletion causes a fatal defect in murine pulmonary Staphylococcus aureus clearance.
J Surg Res Volume: 150 Page(s): 278 - 285
12/01/2008 Authors: Robertson CM; Perrone EE; McConnell KW; Dunne WM; Boody B; Brahmbhatt T; Diacovo MJ; Van Rooijen N; Hogue LA; Cannon CL -
SITE AND SOURCE OF INFECTION MEDIATE LOCAL AND SYSTEMIC HOST RESPONSE IN SEPTIC MICE.
Volume: 36 Page(s): A38 - A38
12/01/2008 Authors: Clark AT; Hotchkiss WR; Zee-Cheng BR; Clark JA; Fox AC; McConnell KW; Dunne WM; Buchman TG; Coopersmith CM -
CATHETER-RELATED BLOODSTREAM INFECTION RATES IN MINOCYCLINE/RIFAMPIN VS. CHLORHEXIDINE/SILVER SULFADIAZINE-IMPREGNATED CENTRAL VENOUS CATHETERS - RESULTS OF A 46 MONTH STUDY
Volume: 36 Page(s): A113 - A113
12/01/2008 Authors: Schuerer DJ; Mazuski JE; Buchman TG; Coopersmith CM; Sona CS; Schallom ME; McMullen K; Doll S; Warren DK; Fraser VJ -
INTESTINAL OVEREXPRESSION OF BCL-2 DECREASES GUT EPITHELIAL APOPTOSIS AND IMPROVES SURVIVAL IN MICE SUBJECTED TO WHOLE BODY IRRADIATION FOLLOWED BY MRSA PNEUMONIA.
Volume: 36 Page(s): A42 - A42
12/01/2008 Authors: Jung E; Clark JA; Clark AT; Fox AC; Dunne WM; Buchman TG; Coopersmith CM; Brahmamdam P; Davis CG; McDonough JS -
Multicenter implementation of a consensus-developed, evidence-based, spontaneous breathing trial protocol.
Crit Care Med Volume: 36 Page(s): 2753 - 2762
10/01/2008 Authors: Robertson TE; Mann HJ; Hyzy R; Rogers A; Douglas I; Waxman AB; Weinert C; Alapat P; Guntupalli KK; Buchman TG -
Pharmacoepidemiology of QT-interval prolonging drug administration in critically ill patients.
Pharmacoepidemiol Drug Saf Volume: 17 Page(s): 971 - 981
10/01/2008 Authors: Freeman BD; Dixon DJ; Coopersmith CM; Zehnbauer BA; Buchman TG -
Physiological noise versus white noise to drive a variable ventilator in a porcine model of lung injury.
Can J Anaesth Volume: 55 Page(s): 577 - 586
09/01/2008 Authors: Froehlich KF; Graham MR; Buchman TG; Girling LG; Scafetta N; West BJ; Walker EK-Y; McManus BM; Mutch WAC -
Myocardial transcriptional profiles in a murine model of sepsis: evidence for the importance of age.
Pediatr Crit Care Med Volume: 9 Page(s): 530 - 535
09/01/2008 Authors: Checchia PA; Schierding W; Polpitiya A; Dixon D; Macmillan S; Muenzer J; Stromberg P; Coopersmith CM; Buchman TG; Cobb JP -
Is there a role for growth hormone therapy in refractory critical illness?
Curr Opin Crit Care Volume: 14 Page(s): 438 - 444
08/01/2008 Authors: Taylor BE; Buchman TG -
Epidermal growth factor treatment decreases mortality and is associated with improved gut integrity in sepsis.
Shock Volume: 30 Page(s): 36 - 42
07/01/2008 Authors: Clark JA; Clark AT; Hotchkiss RS; Buchman TG; Coopersmith CM -
Tracheostomy protocol: experience with development and potential utility.
Crit Care Med Volume: 36 Page(s): 1742 - 1748
06/01/2008 Authors: Freeman BD; Kennedy C; Robertson TE; Coopersmith CM; Schallom M; Sona C; Cracchiolo L; Schuerer DJE; Boyle WA; Buchman TG -
Autonomic information flow improves prognostic value of heart rate patterns after abdominal aortic surgery.
J Crit Care Volume: 23 Page(s): 255 - 262
06/01/2008 Authors: Hoyer D; Friedrich H; Stein PK; Domitrovich PP; Hoyer H; Faldu C; Buchman TG -
Intestine-specific overexpression of IL-10 improves survival in polymicrobial sepsis.
Shock Volume: 29 Page(s): 483 - 489
04/01/2008 Authors: Rajan S; Vyas D; Clark AT; Woolsey CA; Clark JA; Hotchkiss RS; Buchman TG; Coopersmith CM -
Improved extubation rates and earlier liberation from mechanical ventilation with implementation of a daily spontaneous-breathing trial protocol.
J Am Coll Surg Volume: 206 Page(s): 489 - 495
03/01/2008 Authors: Robertson TE; Sona C; Schallom L; Buckles M; Cracchiolo L; Schuerer D; Coopersmith CM; Song F; Buchman TG -
Mathematical estimates of recovery after loss of activity: II. Long-range connectivity facilitates rapid functional recovery.
Crit Care Med Volume: 36 Page(s): 489 - 494
02/01/2008 Authors: Hbler MJ; Buchman TG -
Achieving the aims of education: curricular decisions in critical care.
Crit Care Volume: 12 Page(s): 188
01/01/2008 Authors: Buchman TG -
Anti-TNF modulates mortality from S. pneumoniae and P. aeruginosa pneumonia in mice
Volume: 29 Page(s): 97 - 97
01/01/2008 Authors: Clark AT; McConnell KW; Dunne WM; Dixon DJ; Cobb JP; Buchman TG; Hotchkiss RS; Coopersmith CM -
Sepsis from pseudomonas aeruginosa pneumonia superimposed on pancreatic cancer increases gut epithelial apoptosis, bacteremia, and mortality
Volume: 29 Page(s): 95 - 95
01/01/2008 Authors: Fox A; Robertson C; Belt B; Dunne WM; Linehan D; Buchman T; Hotchkiss R; Coopersmith C -
Radiation injury increases systemic infection and mortality in murine MRSA pneumonia
Volume: 29 Page(s): 100 - 100
01/01/2008 Authors: Perrone EE; Brahmamdan P; Davis CG; McDonough JS; Buchman TG; Hotchkiss RS; Coopersmith CM -
Intestinal overexpression of epidermal growth factor inhibits gut epithelial apoptosis and improves mortality in sepsis
Volume: 29 Page(s): 99 - 100
01/01/2008 Authors: Clark JA; Hotchkiss RS; Buchman TG; Coopersmith CM -
Sepsis from pseudomonas aeruginosa pneumonia decreases jejunal epithelial proliferation and migration with partial recovery of regenerative capacity 48 hours post-injury
Volume: 35 Page(s): A54 - A54
12/01/2007 Authors: Fox AC; Clark AT; Zee-Cheng B; Dunne WM; Buchman TG; Hotchkiss RS; Coopersmith CM -
NF-kappa B activation in enterocytes reduces sepsis-induced gut injury
Volume: 35 Page(s): A3 - A3
12/01/2007 Authors: Clark J; Samocha A; Hotchkiss R; Buchman T; Coopersmith C -
Novel models of murine sepsis with comorbid pancreatic cancer
Volume: 35 Page(s): A57 - A57
12/01/2007 Authors: Hotchkiss RS; Robertson CM; Belt BA; Linehan DC; Buchman TG; Coopersmith CM -
Loss of EGF receptor activity leads to increased intestinal apoptosis and decreased villus height in sepsis
Volume: 35 Page(s): A52 - A52
12/01/2007 Authors: Perrone E; Clark J; Hotchkiss R; Buchman T; Coopersmith C -
Age increases local but not systemic inflammation in murine sepsis
Volume: 35 Page(s): A61 - A61
12/01/2007 Authors: Clark AT; Turnbull IR; Stromberg PE; Woolsey CA; Buchman TG; Horchkiss RS; Coopersmith CM -
Tumor necrosis factor-beta polymorphism is associated with predisposition to severe sepsis and longer mechanical ventilation
Volume: 35 Page(s): A15 - A15
12/01/2007 Authors: Watanabe E; Buchman TG; Zehnbauer BA -
Effect of chlorhexidine/silver sulfadiazine-impregnated central venous catheters in an intensive care unit with a low blood stream infection rate after implementation of an educational program: a before-after trial.
Surg Infect (Larchmt) Volume: 8 Page(s): 445 - 454
08/01/2007 Authors: Schuerer DJE; Zack JE; Thomas J; Borecki IB; Sona CS; Schallom ME; Venker M; Nemeth JL; Ward MR; Verjan L -
Biologically variable ventilation improves gas exchange and respiratory mechanics in a model of severe bronchospasm.
Crit Care Med Volume: 35 Page(s): 1749 - 1755
07/01/2007 Authors: Mutch WAC; Buchman TG; Girling LG; Walker EK-Y; McManus BM; Graham MR -
Mathematical estimation of recovery after loss of activity: I. Renal failure.
J Trauma Volume: 63 Page(s): 232 - 238
07/01/2007 Authors: Hbler MJ; Buchman TG -
Relationship between heritable factors and acute physiology with respect to the predisposition to sepsis
Volume: 27 Page(s): 49 - 49
06/01/2007 Authors: Watanabe E; Buchman TG; Zehnbauer B -
Neutrophil depletion inhibits pulmonary clearance of Stahpylocuccus aureus in mice
Volume: 27 Page(s): 47 - 47
06/01/2007 Authors: Robertson C; McConnell K; Martin J; Boody B; Dunne M; Hotchkiss R; Buchman T; Coopersmith C -
Aging modulates local but not systemic inflammation following cecal ligation and puncture (CLP) in mice
Volume: 27 Page(s): 54 - 55
06/01/2007 Authors: Clark A; Turnbull I; Stromberg P; Woolsey C; Buchman T; Hotchkiss R; Coopersmith C -
Differences in duration of mechanical ventilation after tracheostomy
Volume: 27 Page(s): 46 - 46
06/01/2007 Authors: Robertson TE; Sona C; Schallom L; Cracchiolo L; Buckles M; Song F; Schuerer D; Buchman T -
Decreased mortality following epidermal growth factor treatment is associated with improved gut integrity in sepsis
Volume: 27 Page(s): 1 - 1
06/01/2007 Authors: Clark J; Hotchkiss R; Buchman T; Coopersmith C -
The survival advantage conferred by prevention of gut epithelial apoptosis in sepsis occurs through the mitochondrial pathway and is dependent upon the presence of the adaptive immune system
Volume: 27 Page(s): 5 - 5
06/01/2007 Authors: McConnell K; Stromberg P; Woolsey C; Clark A; Clark J; Hotchkiss R; Buchman T; Coopersmith C -
Epithelial apoptosis in mechanistically distinct methods of injury in the murine small intestine.
Histol Histopathol Volume: 22 Page(s): 623 - 630
06/01/2007 Authors: Vyas D; Robertson CM; Stromberg PE; Martin JR; Dunne WM; Houchen CW; Barrett TA; Ayala A; Perl M; Buchman TG -
Protocol-driven daily spontaneous breathing trials are feasible and safe in intubated trauma patients
Volume: 56 Page(s): S218 - S219
03/01/2007 Authors: Robertson TE; Cracchiolo L; Schallom L; Sona C; Schuerer D; Buchman T -
Use of a trauma registry to monitor length of stay and discharge disposition by payor source at a US level I trauma center
Volume: 56 Page(s): S232 - S233
03/01/2007 Authors: Kirby J; Carroll W; Glasgow S; Nash J; Buchman T; Schuerer D -
Exogenous epidermal growth factor improves intestinal integrity in sepsis
INFLAMMATION RESEARCH Volume: 56 Page(s): S174 - S174
03/01/2007 Authors: Clark J; Stromberg P; Hotchkiss R; Buchman T; Coopersmith C -
Sepsis from pseudomonas aeruginosa pneumonia decreases intestinal epithelial proliferation and slows migration
INFLAMMATION RESEARCH Volume: 56 Page(s): S158 - S158
03/01/2007 Authors: Clark AT; Woolsey CA; Dunne WM; Buchman TG; Hotchkiss RS; Coopersmith CM -
Patients' and surrogates' perspective on research and testing in critical care.
Crit Care Med Volume: 35 Page(s): 328 - 329
01/01/2007 Authors: Freeman BD; Kennedy CR; Coopersmith CM; Zehnbauer BA; Buchman TG -
Increase in extubation rate with implementation of daily spontaneous breathing trials.
Volume: 34 Page(s): A87 - A87
12/01/2006 Authors: Robertson TE; Cracchiolo L; Marcy B; Schallom L; Carrie S; Song F; Douglas S; Coopersmith C; Buchman TG -
Neutrophil depletion allows creation of a virulent murine model of staphylococcus aureus pneumonia.
Volume: 34 Page(s): A35 - A35
12/01/2006 Authors: Robertson CM; Martin J; Boody B; Dunne M; Hotchkiss R; Buchman T; Coopersmith CM -
The relationship between the surgeon and the intensivist in the surgical intensive care unit.
Surg Clin North Am Volume: 86 Page(s): 1351 - 1357
12/01/2006 Authors: Penkoske PA; Buchman TG -
Molecular diagnostics in sepsis: from bedside to bench.
J Am Coll Surg Volume: 203 Page(s): 585 - 598
11/01/2006 Authors: Chung TP; Laramie JM; Meyer DJ; Downey T; Tam LHY; Ding H; Buchman TG; Karl I; Stormo GD; Hotchkiss RS -
Modeling aging and sepsis.
Volume: 25 Page(s): 13 - 14
06/01/2006 Authors: Tumbull I; Buchman T; Coopersmith C -
An examination of mechanisms underlying the survival benefit conferred by intestinespecific overexpression of interleukin-10.
Volume: 25 Page(s): 47 - 47
06/01/2006 Authors: Rajan S; Woolsey C; Buchman T; Hotchkiss R; Coopersmith C -
Gram positive and gram negative murine pneumonia induce unique local cytokine profiles.
Volume: 25 Page(s): 47 - 47
06/01/2006 Authors: McConnell K; Dunne M; Buchman T; Hotchkiss R; Coopersmith C -
HSP70.1 and HSP70.3 mediate survival following cecal ligation and puncture in aged male mice.
Volume: 25 Page(s): 7 - 8
06/01/2006 Authors: Clark AT; McConnell KW; Hunt CR; Buchman TG; Hotchkiss RS; Coopersmith CM -
Aged mice have altered cytokine profiles and intestinal permeability following cecal ligation and puncture.
Volume: 25 Page(s): 76 - 77
06/01/2006 Authors: Woolsey CA; Stromberg PE; Hotchkiss RS; Buchman TG; Coopersmith CM -
A new safety event reporting system improves physician reporting in the surgical intensive care unit.
J Am Coll Surg Volume: 202 Page(s): 881 - 887
06/01/2006 Authors: Schuerer DJE; Nast PA; Harris CB; Krauss MJ; Jones RM; Boyle WA; Buchman TG; Coopersmith CM; Dunagan WC; Fraser VJ -
Enhancing the use of clinical guidelines: a social norms perspective.
J Am Coll Surg Volume: 202 Page(s): 826 - 836
05/01/2006 Authors: McDonnell Norms Group -
Genetic research and testing in critical care: surrogates' perspective.
Crit Care Med Volume: 34 Page(s): 986 - 994
04/01/2006 Authors: Freeman BD; Kennedy CR; Coopersmith CM; Zehnbauer BA; Buchman TG -
Heart rate variability and its association with mortality in prehospital trauma patients.
J Trauma Volume: 60 Page(s): 363 - 370
02/01/2006 Authors: Cooke WH; Salinas J; Convertino VA; Ludwig DA; Hinds D; Duke JH; Moore FA; Holcomb JB -
Efficacy and safety of an insulin infusion protocol in a surgical ICU.
J Am Coll Surg Volume: 202 Page(s): 1 - 9
01/01/2006 Authors: Taylor BE; Schallom ME; Sona CS; Buchman TG; Boyle WA; Mazuski JE; Schuerer DE; Thomas JM; Kaiser C; Huey WY -
Intestine specific overexpression of IL-10 improves survival in a polymicrobial model of sepsis.
Volume: 33 Page(s): A133 - A133
12/01/2005 Authors: Rajan S; Vyas D; Buchman TG; Coopersmith CM; Hotchkiss RS -
A simple, low-cost oral care protocol reduces ventilator-associated pneumonia rates.
Volume: 33 Page(s): A13 - A13
12/01/2005 Authors: Sona C; Zack J; Schallom L; Schwartkopf L; Huey W; McSweeney M; McMullen K; Mazuski J; Schuerer D; Coopersmith C -
Identifying the optimal method to quantify gut apoptosis in critical illness
Volume: 33 Page(s): A145 - A145
12/01/2005 Authors: Robertson CM; Stromberg P; Vyas D; Martin J; Sherman B; Buchman T; Coopersmith C; Hotchkiss R -
Daily spontaneous breathing trials: Opportunities created - And missed
Volume: 33 Page(s): A116 - A116
12/01/2005 Authors: Cracchioio L; Buckles M; Schallom L; Sona C; Schuerer D; Buchman T; Robertson TE -
RNAi.
Crit Care Med Volume: 33 Page(s): S441 - S443
12/01/2005 Authors: Buchman TG -
P2X7 adrenergic receptor genotype suggests association with survival in severe sepsis.
Volume: 33 Page(s): A133 - A133
12/01/2005 Authors: Bhattacharya SD; Zehnbauer BA; Buchman TG -
The effect of age on myocardial gene expression profiles in a murine model of sepsis
Volume: 33 Page(s): A142 - A142
12/01/2005 Authors: Checchia PA; Polpitiya A; MacMillan S; Stromberg P; Coopersmith CM; Buchman TG; Cobb JP -
Relationship between tracheostomy timing and duration of mechanical ventilation in critically ill patients.
Crit Care Med Volume: 33 Page(s): 2513 - 2520
11/01/2005 Authors: Freeman BD; Borecki IB; Coopersmith CM; Buchman TG -
Mechanisms of decreased intestinal epithelial proliferation and increased apoptosis in murine acute lung injury.
Crit Care Med Volume: 33 Page(s): 2350 - 2357
10/01/2005 Authors: Husain KD; Stromberg PE; Woolsey CA; Turnbull IR; Dunne WM; Javadi P; Buchman TG; Karl IE; Hotchkiss RS; Coopersmith CM -
Early antibiotic administration but not antibody therapy directed against IL-6 improves survival in septic mice predicted to die on basis of high IL-6 levels.
Am J Physiol Regul Integr Comp Physiol Volume: 289 Page(s): R1048 - R1053
10/01/2005 Authors: Vyas D; Javadi P; Dipasco PJ; Buchman TG; Hotchkiss RS; Coopersmith CM -
A visual, timeline-based display of evidence for emergency thoracotomy.
J Trauma Volume: 59 Page(s): 773 - 777
09/01/2005 Authors: Hall BL; Buchman TG -
Iron dysregulation combined with aging prevents sepsis-induced apoptosis.
J Surg Res Volume: 128 Page(s): 37 - 44
09/01/2005 Authors: Javadi P; Buchman TG; Stromberg PE; Turnbull IR; Vyas D; Hotchkiss RS; Karl IE; Coopersmith CM -
Gram positive and gram negative murine pneumonia induce distinct changes in lymphocyte apoptosis and neutrophil migration.
Volume: 23 Page(s): 55 - 55
06/01/2005 Authors: McConnell K; DiPasco P; Chang K; Schreiber T; Vyas D; Dunne M; Buchman T; Hotchkiss R; Coopersmith C -
Evaluation of the applicability, efficacy, and safety of a thromboembolic event prophylaxis guideline designed for quality improvement of the traumatically injured patient.
Volume: 58 Page(s): 731 - 739
04/01/2005 Authors: Schuerer DJE; Whinney RR; Freeman BD; Nash J; Prasad S; Krem MM; Mazuski JE; Buchman TG -
Emergency department resuscitative thoracotomy.
J Am Coll Surg Volume: 200 Page(s): 148
01/01/2005 Authors: Buchman TG -
In vivo, in vitro, in silico..
Crit Care Med Volume: 32 Page(s): 2159 - 2160
10/01/2004 Authors: Buchman TG -
Nonlinear dynamics, complex systems, and the pathobiology of critical illness.
Curr Opin Crit Care Volume: 10 Page(s): 378 - 382
10/01/2004 Authors: Buchman TG -
Age disproportionately increases sepsis-induced apoptosis in the spleen and gut epithelium.
Shock Volume: 22 Page(s): 364 - 368
10/01/2004 Authors: Turnbull IR; Buchman TG; Javadi P; Woolsey CA; Hotchkiss RS; Karl IE; Coopersmith CM -
Sequence makes a difference: paradoxical effects of stress in vivo.
Shock Volume: 22 Page(s): 229 - 233
09/01/2004 Authors: Wizorek JJ; Coopersmith CM; Laramie JM; Tong A; Stromberg PE; Hotchkiss RS; Buchman TG; Cobb JP -
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms.
Nature Volume: 429 Page(s): 75 - 79
05/06/2004 Authors: Saleh M; Vaillancourt JP; Graham RK; Huyck M; Srinivasula SM; Alnemri ES; Steinberg MH; Nolan V; Baldwin CT; Hotchkiss RS -
High-dose exogenous iron following cecal ligation and puncture increases mortality rate in mice and is associated with an increase in gut epithelial and splenic apoptosis.
Crit Care Med Volume: 32 Page(s): 1178 - 1185
05/01/2004 Authors: Javadi P; Buchman TG; Stromberg PE; Husain KD; Dunne WM; Woolsey CA; Turnbull IR; Hotchkiss RS; Karl IE; Coopersmith CM -
The impact of bedside behavior on catheter-related bacteremia in the intensive care unit.
Arch Surg Volume: 139 Page(s): 131 - 136
02/01/2004 Authors: Coopersmith CM; Zack JE; Ward MR; Sona CS; Schallom ME; Everett SJ; Huey WY; Garrison TM; McDonald J; Buchman TG -
Treatment of hypophosphatemia using a protocol based on patient weight and serum phosphorus level in a surgical intensive care unit.
J Am Coll Surg Volume: 198 Page(s): 198 - 204
02/01/2004 Authors: Taylor BE; Huey WY; Buchman TG; Boyle WA; Coopersmith CM -
Antibiotics improve survival in sepsis independent of injury severity but do not change mortality in mice with markedly elevated interleukin 6 levels.
Shock Volume: 21 Page(s): 121 - 125
02/01/2004 Authors: Turnbull IR; Javadi P; Buchman TG; Hotchkiss RS; Karl IE; Coopersmith CM -
Exogenous iron after sepsis increases mortality and an alters apoptosis
Volume: 21 Page(s): 130 - 130
01/01/2004 Authors: Javadi P; Stromberg PE; Husain KD; Woolsey CA; Buchman TG; Karl IE; Hotchkiss RS; Coopersmith CM -
Lung injury uncouples gut apoptosis and proliferation
Volume: 21 Page(s): 55 - 55
01/01/2004 Authors: Husain KD; Stromberg PE; Woolsey CA; Turnbull IR; Buchman TG; Karl IE; Hotchkiss RS; Coopersmith CM -
Gut epithelial and splenic apoptosis in septic HFE-/- mice are age dependent
Volume: 21 Page(s): 33 - 33
01/01/2004 Authors: Javadi P; Buchman TG; Turnbull IR; Stromberg PE; Coopersmith CM -
The adaptive immune system mediates gut epithelial apoptosis following cecal ligation and puncture
Volume: 21 Page(s): 39 - 39
01/01/2004 Authors: Woolsey CA; Stromberg PE; Javadi P; Husain KD; Chang KC; Hotchkiss RS; Karl IE; Buchman TG; Coopersmith CM -
Use of clonidine to decrease intestinal fluid losses in patients with high-output short-bowel syndrome.
JPEN J Parenter Enteral Nutr Volume: 28 Page(s): 265 - 268
01/01/2004 Authors: McDoniel K; Taylor B; Huey W; Eiden K; Everett S; Fleshman J; Buchman TG; Alpers D; Klein S -
Gut epithelial apoptosis occurs via the mitochondrial and receptor-mediated pathways in streptococcus pneumoniae pneumonia
Volume: 21 Page(s): 22 - 22
01/01/2004 Authors: Husain KD; Stromberg PE; Woolsey CA; Dunne WM; Buchman TG; Karl IE; Hotchkiss RS; Coppersmith CM -
Mice expressing caspase-3 resistant retinoblastoma protein have decreased gut epithelial but not splenic apoptosis in Pseudomonas aeruginosa pneumonia
Volume: 21 Page(s): 37 - 37
01/01/2004 Authors: Stromberg PE; Woolsey CA; Husain KD; Dunne WM; Buchman TG; Karl IE; Hotchkiss RS; Coopersmith CM -
Gut over-expression of Bcl-2 requires lymphocytes to improve survival
Volume: 21 Page(s): 54 - 54
01/01/2004 Authors: Stromberg PE; Chang KC; Woolsey CW; Hotchkiss WR; Buchman TG; Karl IE; Hotchkiss RS; Coopersmith CM -
Gut apoptosis and proliferation in acute lung injury: The role of Bcl-2, TLR4, and TNF
Volume: 31 Page(s): A1 - A1
12/01/2003 Authors: Husain KD; Stromberg PE; Woolsey CA; Hotchkiss WR; Buchman TG; Hotchkiss RS; Karl IE; Coopersmith CM -
National estimates of hospitalization charges for the acute care of traumatic brain injuries.
Brain Inj Volume: 17 Page(s): 983 - 990
11/01/2003 Authors: Schootman M; Buchman TG; Lewis LM -
Bcl-2 inhibits gut epithelial apoptosis induced by acute lung injury in mice but has no effect on survival.
Shock Volume: 20 Page(s): 437 - 443
11/01/2003 Authors: Husain KD; Stromberg PE; Javadi P; Buchman TG; Karl IE; Hotchkiss RS; Coopersmith CM -
The surgical intensivist as mediator of end-of-life issues in the care of critically ill patients.
J Am Coll Surg Volume: 197 Page(s): 847 - 853
11/01/2003 Authors: Eachempati SR; Miller FG; Fins JJ -
Guidelines for the selection of anti-infective agents for complicated intra-abdominal infections.
Clin Infect Dis Volume: 37 Page(s): 997 - 1005
10/15/2003 Authors: Solomkin JS; Mazuski JE; Baron EJ; Sawyer RG; Nathens AB; DiPiro JT; Buchman T; Dellinger EP; Jernigan J; Gorbach S -
Open versus closed units: chaos versus a well-oiled machine.
Crit Care Med Volume: 31 Page(s): 2567 - 2568
10/01/2003 Authors: Marik PE -
A meta-analysis of controlled trials of anticoagulant therapies in patients with sepsis.
Shock Volume: 20 Page(s): 5 - 9
07/01/2003 Authors: Freeman BD; Zehnbauer BA; Buchman TG -
Iron overload before cecal ligation and puncture increases mortality.
Shock Volume: 20 Page(s): 52 - 55
07/01/2003 Authors: Wizorek JJ; Turnbull IR; Buchman TG -
Families' perceptions of surgical intensive care.
J Am Coll Surg Volume: 196 Page(s): 977 - 983
06/01/2003 Authors: Buchman TG; Ray SE; Wax ML; Cassell J; Rich D; Niemczycki MA -
Sepsis from Pseudomonas aeruginosa pneumonia decreases intestinal proliferation and induces gut epithelial cell cycle arrest.
Crit Care Med Volume: 31 Page(s): 1630 - 1637
06/01/2003 Authors: Coopersmith CM; Stromberg PE; Davis CG; Dunne WM; Amiot DM; Karl IE; Hotchkiss RS; Buchman TG -
Antibiotics improve survival and alter the inflammatory profile in a murine model of sepsis from Pseudomonas aeruginosa pneumonia.
Shock Volume: 19 Page(s): 408 - 414
05/01/2003 Authors: Coopersmith CM; Amiot DM; Stromberg PE; Dunne WM; Davis CG; Osborne DF; Husain KD; Turnbull IR; Karl IE; Hotchkiss RS -
Robert Wood Johnson Foundation Office of Promoting Excellence in End-of-Life Care: executive summary of the report from the field.
Volume: 196 Page(s): 807 - 815
05/01/2003 Authors: Surgeons Palliative Care Workshop -
Surgeons, intensivists, and the covenant of care: administrative models and values affecting care at the end of life--Updated.
Crit Care Med Volume: 31 Page(s): 1551 - 1557
05/01/2003 Authors: Cassell J; Buchman TG; Streat S; Stewart RM -
Effects of age on mortality and antibiotic efficacy in cecal ligation and puncture.
Shock Volume: 19 Page(s): 310 - 313
04/01/2003 Authors: Turnbull IR; Wlzorek JJ; Osborne D; Hotchkiss RS; Coopersmith CM; Buchman TG -
Critical care: on target.
Crit Care Med Volume: 31 Page(s): 1003 - 1005
04/01/2003 Authors: Buchman TG -
Surgeons, intensivists, and the covenant of care: administrative models and values affecting care at the end of life.
Crit Care Med Volume: 31 Page(s): 1263 - 1270
04/01/2003 Authors: Cassell J; Buchman TG; Streat S; Stewart RM; Buchman TG -
A meta-analysis of anticoagulant therapies in patients with sepsis
Volume: 31 Page(s): A101 - A101
02/01/2003 Authors: Freeman BD; Buchman TG; Zehnbauer BA -
Aging is associated with increased IL-6 and splenic apoptosis following cecal ligation and puncture
Volume: 31 Page(s): A9 - A9
02/01/2003 Authors: Javadi P; Turnbull IR; Coopersmith CM; Buchman TG; Hotchkiss RS -
Acute lung injury causes increased gut epithelial apoptosis and decreased proliferation in mice
Volume: 31 Page(s): A10 - A10
02/01/2003 Authors: Husain KD; Stromberg PE; Turnbull IR; Buchman TG; Coopersmith CM; Hotchkiss RS; Dunne WM; Karl IE -
Template-directed dye-terminator incorporation with fluorescence polarization detection for analysis of single nucleotide polymorphisms associated with cardiovascular and thromboembolic disease.
Thromb Res Volume: 111 Page(s): 373 - 379
01/01/2003 Authors: Freeman BD; Buchman TG; Zehnbauer BA -
Computerized content analysis of conversational interactions.
Comput Inform Nurs Volume: 21 Page(s): 249 - 258
01/01/2003 Authors: Gottschalk LA; Bechtel RJ; Buchman TG; Ray SE -
A meta-analysis of anticoagulant therapies in patients with sepsis
Volume: 30 Page(s): A101 - A101
12/01/2002 Authors: Freeman BD; Buchman TG -
Aging is associated with increased IL-6 and splenic apoptosis following cecal ligation and puncture
Volume: 30 Page(s): A9 - A9
12/01/2002 Authors: Javadi P; Turnbull IR; Coopersmith CM; Buchman TG -
Sepsis gene expression profiling: murine splenic compared with hepatic responses determined by using complementary DNA microarrays.
Crit Care Med Volume: 30 Page(s): 2711 - 2721
12/01/2002 Authors: Cobb JP; Laramie JM; Stormo GD; Morrissey JJ; Shannon WD; Qiu Y; Karl IE; Buchman TG; Hotchkiss RS -
Acute lung injury causes increased gut epithelial apoptosis and decreased proliferation in mice
Volume: 30 Page(s): A10 - A10
12/01/2002 Authors: Husain KD; Stromberg PE; Turnbull IR; Buchman TG; Coopersmith CM -
The community of the self.
Nature Volume: 420 Page(s): 246 - 251
11/14/2002 Authors: Buchman TG -
Template-directed dye-terminator incorporation with fluorescence polarization detection for analysis of single nucleotide polymorphisms implicated in sepsis.
J Mol Diagn Volume: 4 Page(s): 209 - 215
11/01/2002 Authors: Freeman BD; Buchman TG; McGrath S; Tabrizi AR; Zehnbauer BA -
High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults: a randomized, controlled trial.
Am J Respir Crit Care Med Volume: 166 Page(s): 801 - 808
09/15/2002 Authors: Derdak S; Mehta S; Stewart TE; Smith T; Rogers M; Buchman TG; Carlin B; Lowson S; Granton J; Multicenter Oscillatory Ventilation For Acute Respiratory Distress Syndrome Trial (MOAT) Study Investigators -
Heart rate variability in critical illness and critical care.
Curr Opin Crit Care Volume: 8 Page(s): 311 - 315
08/01/2002 Authors: Buchman TG; Stein PK; Goldstein B -
Who should manage the dying patient?: Rescue, shame, and the surgical ICU dilemma.
J Am Coll Surg Volume: 194 Page(s): 665 - 673
05/01/2002 Authors: Buchman TG; Cassell J; Ray SE; Wax ML -
Inhibition of intestinal epithelial apoptosis and survival in a murine model of pneumonia-induced sepsis.
JAMA Volume: 287 Page(s): 1716 - 1721
04/03/2002 Authors: Coopersmith CM; Stromberg PE; Dunne WM; Davis CG; Amiot DM; Buchman TG; Karl IE; Hotchkiss RS -
Serum levels of Hsp 72 measured early after trauma correlate with survival - Comment
JOURNAL OF TRAUMA-INJURY INFECTION AND CRITICAL CARE Volume: 52 Page(s): 617 - 617
04/01/2002 Authors: Buchman TG -
Sedation modulates recognition of novel stimuli and adaptation to regular stimuli in critically ill adults.
Crit Care Med Volume: 30 Page(s): 609 - 616
03/01/2002 Authors: Clifford JO; Buchman TG -
The frequency and effects of cytochrome P450 (CYP) 2C9 polymorphisms in patients receiving warfarin.
J Am Coll Surg Volume: 194 Page(s): 267 - 273
03/01/2002 Authors: Tabrizi AR; Zehnbauer BA; Borecki IB; McGrath SD; Buchman TG; Freeman BD -
Overexpression of Bcl-2 in the intestinal epithelium improves survival in septic mice.
Crit Care Med Volume: 30 Page(s): 195 - 201
01/01/2002 Authors: Coopersmith CM; Chang KC; Swanson PE; Tinsley KW; Stromberg PE; Buchman TG; Karl IE; Hotchkiss RS -
Coagulation inhibitors in the treatment of sepsis.
Expert Opin Investig Drugs Volume: 11 Page(s): 69 - 74
01/01/2002 Authors: Freeman BD; Buchman TG -
Effect of an education program on decreasing catheter-related bloodstream infections in the surgical intensive care unit.
Crit Care Med Volume: 30 Page(s): 59 - 64
01/01/2002 Authors: Coopersmith CM; Rebmann TL; Zack JE; Ward MR; Corcoran RM; Schallom ME; Sona CS; Buchman TG; Boyle WA; Polish LB -
Overexpression of Bcl-2 in the intestinal epithelium improves survival in a model of pseudomonas pneumonia-induced sepsis
CRITICAL CARE MEDICINE Volume: 29 Page(s): A9 - A9
12/01/2001 Authors: Coopersmith CM; Stromberg PE; Dunne WM; Davis CG; Buchman TG; Hotchkiss RS -
Mortality and circulating TNF alpha increase with advanced age in experimental intraabdominal sepsis
CRITICAL CARE MEDICINE Volume: 29 Page(s): A43 - A43
12/01/2001 Authors: Wizorek JJ; Turnbull IR; Hotchkiss RS; Tinsley KW; Osborne DF; Cobb JP; Buchman TG -
Clinical effectiveness of a phosphorus repletion protocol in a surgical intensive care unit
CRITICAL CARE MEDICINE Volume: 29 Page(s): A161 - A161
12/01/2001 Authors: Taylor B; Huey W; Coopersmith C; Buchman T -
Role of apoptosis in Pseudomonas aeruginosa pneumonia.
Science Volume: 294 Page(s): 1783
11/30/2001 Authors: Hotchkiss RS; Dunne WM; Swanson PE; Davis CG; Tinsley KW; Chang KC; Buchman TG; Karl IE -
Complex systems analysis: a tool for shock research.
Shock Volume: 16 Page(s): 248 - 251
10/01/2001 Authors: Buchman TG; Cobb JP; Lapedes AS; Kepler TB -
Percutaneous dilational tracheostomy vs open tracheostomy
CHEST Volume: 120 Page(s): 1424 - 1424
10/01/2001 Authors: Freeman BD; Isabella K; Lin N; Buchman TG -
microArRAY of hope.
Shock Volume: 16 Page(s): 264 - 265
10/01/2001 Authors: Cobb JP; Buchman TG -
Shock at the millennium II. Walter B. Cannon and Lawrence J. Henderson.
Shock Volume: 16 Page(s): 278 - 284
10/01/2001 Authors: Chambers NK; Buchman TG -
Percutaneous dilational tracheostomy vs. open tracheostomy.
Chest Volume: 120 Page(s): 1423 - 1424
10/01/2001 Authors: Anderson JD; Rabinovici R; Frankel HL -
Association between heart rate variability recorded on postoperative day 1 and length of stay in abdominal aortic surgery patients.
Crit Care Med Volume: 29 Page(s): 1738 - 1743
09/01/2001 Authors: Stein PK; Schmieg RE; El-Fouly A; Domitrovich PP; Buchman TG -
Sepsis-induced apoptosis causes progressive profound depletion of B and CD4+ T lymphocytes in humans.
J Immunol Volume: 166 Page(s): 6952 - 6963
06/01/2001 Authors: Hotchkiss RS; Tinsley KW; Swanson PE; Schmieg RE; Hui JJ; Chang KC; Osborne DF; Freeman BD; Cobb JP; Buchman TG -
Extreme warfarin sensitivity in siblings associated with multiple cytochrome P450 polymorphisms.
Am J Hematol Volume: 67 Page(s): 144 - 146
06/01/2001 Authors: Tabrizi AR; McGrath SD; Blinder MA; Buchman TG; Zehnbauer BA; Freeman BD -
Population differences in von Willebrand factor levels affect the diagnosis of von Willebrand disease in African-American women.
Am J Hematol Volume: 67 Page(s): 125 - 129
06/01/2001 Authors: Miller CH; Dilley A; Richardson L; Hooper WC; Evatt BL -
A prospective, randomized study comparing percutaneous with surgical tracheostomy in critically ill patients.
Crit Care Med Volume: 29 Page(s): 926 - 930
05/01/2001 Authors: Freeman BD; Isabella K; Cobb JP; Boyle WA; Schmieg RE; Kolleff MH; Lin N; Saak T; Thompson EC; Buchman TG -
Genetic susceptibility to hemorrhagic complications during warfarin therapy.
Surgery Volume: 129 Page(s): 645 - 646
05/01/2001 Authors: Tabrizi AR; Freeman BD; Buchman TG; Zehnbauer BA -
Interleukin-1 receptor antagonist as therapy for inflammatory disorders.
Expert Opin Biol Ther Volume: 1 Page(s): 301 - 308
03/01/2001 Authors: Freeman BD; Buchman TG -
Injury in the era of genomics.
Shock Volume: 15 Page(s): 165 - 170
03/01/2001 Authors: Cobb JP; Brownstein BH; Watson MA; Shannon WD; Laramie JM; Qiu Y; Stormo GD; Morrissey JJ; Buchman TG; Karl IE -
Genetic markers in sepsis (vol 192, pg 106, 2001)
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS Volume: 192 Page(s): 424 - 424
03/01/2001 Authors: Tabrizi AR; Zehnbauer BA; Freeman BD; Buchman TG -
The heat shock paradox: does NF-kappaB determine cell fate?
FASEB J Volume: 15 Page(s): 270 - 274
01/01/2001 Authors: DeMeester SL; Buchman TG; Cobb JP -
Genetic markers in sepsis.
J Am Coll Surg Volume: 192 Page(s): 106 - 117
01/01/2001 Authors: Tabrizi AR; Zehnbauer BA; Freeman BD; Buchman TG -
Complications associated with intermittent pneumatic compression devices.
Anesthesiology Volume: 93 Page(s): 1556 - 1557
12/01/2000 Authors: Anand A -
Characterization of variability in physiologic time signals during hypotension in pediatric sepsis
CRITICAL CARE MEDICINE Volume: 28 Page(s): A46 - A46
12/01/2000 Authors: Goldstein B; Ellenby MS; Lai S; McNames J; McDonald BA; Krieger D; Sclabassi RJ; Buchman TG -
Complications associated with intermittent pneumatic compression devices - In reply
ANESTHESIOLOGY Volume: 93 Page(s): 1556 - 1557
12/01/2000 Authors: Siddiqui AU; Buchman TG; Hotchkiss RS -
A meta-analysis of prospective trials comparing percutaneous and surgical tracheostomy in critically ill patients.
Chest Volume: 118 Page(s): 1412 - 1418
11/01/2000 Authors: Freeman BD; Isabella K; Lin N; Buchman TG -
The frequency and effects of cytochrome P450 (CYP) polymorphisms in patients receiving warfarin.
Volume: 46 Page(s): 1880 - 1880
11/01/2000 Authors: Freeman B; Tabrizi A; Borecki I; Buchman T; McGrath S; Zehnbauer B -
Injection of iron compounds followed by induction of the stress response causes tissue injury and apoptosis.
Shock Volume: 14 Page(s): 460 - 464
10/01/2000 Authors: Jacob AK; Hotchkiss RS; Swanson PE; Tinsley KW; Karl IE; Buchman TG -
Rapid onset of hepatocyte apoptosis in a patient with trauma.
J Trauma Volume: 49 Page(s): 542 - 546
09/01/2000 Authors: Schmieg RE; Tinsley KW; Swanson PE; Karl IE; Aft R; Buchman TG; Hotchkiss RS -
Monitoring of peripheral nerves and muscle function in patients with multiple organ dysfunction syndrome.
Crit Care Med Volume: 28 Page(s): 3375
09/01/2000 Authors: Latronico N -
Rapid onset of intestinal epithelial and lymphocyte apoptotic cell death in patients with trauma and shock.
Crit Care Med Volume: 28 Page(s): 3207 - 3217
09/01/2000 Authors: Hotchkiss RS; Schmieg RE; Swanson PE; Freeman BD; Tinsley KW; Cobb JP; Karl IE; Buchman TG -
Cytochrome P450 polymorphisms are associated with reduced warfarin dose.
Surgery Volume: 128 Page(s): 281 - 285
08/01/2000 Authors: Freeman BD; Zehnbauer BA; McGrath S; Borecki I; Buchman TG -
Gene in a haystack: tumor necrosis factor polymorphisms and outcome in sepsis.
Crit Care Med Volume: 28 Page(s): 3090 - 3091
08/01/2000 Authors: Freeman BD; Buchman TG -
Comparison of intravenous/oral ciprofloxacin plus metronidazole versus piperacillin/tazobactam in the treatment of complicated intraabdominal infections.
Ann Surg Volume: 232 Page(s): 254 - 262
08/01/2000 Authors: Cohn SM; Lipsett PA; Buchman TG; Cheadle WG; Milsom JW; O'Marro S; Yellin AE; Jungerwirth S; Rochefort EV; Haverstock DC -
Shock at the millennium. I. Walter B. Cannon and Alfred Blalock.
Shock Volume: 13 Page(s): 497 - 504
06/01/2000 Authors: Chambers NK; Buchman TG -
Myocardial infarction as a complication of injury.
J Am Coll Surg Volume: 190 Page(s): 665 - 670
06/01/2000 Authors: Moosikasuwan JB; Thomas JM; Buchman TG -
Role of CuZn superoxide dismutase in regulating lymphocyte apoptosis during sepsis.
Crit Care Med Volume: 28 Page(s): 1701 - 1708
06/01/2000 Authors: Freeman BD; Reaume AG; Swanson PE; Epstein CJ; Carlson EJ; Buchman TG; Karl IE; Hotchkiss RS -
Factor V Leiden mutation in a patient with warfarin-associated skin necrosis.
Surgery Volume: 127 Page(s): 595 - 596
05/01/2000 Authors: Freeman BD; Schmieg RE; McGrath S; Buchman TG; Zehnbauer BA -
p53-dependent and -independent pathways of apoptotic cell death in sepsis.
J Immunol Volume: 164 Page(s): 3675 - 3680
04/01/2000 Authors: Hotchkiss RS; Tinsley KW; Hui JJ; Chang KC; Swanson PE; Drewry AM; Buchman TG; Karl IE -
Pulmonary embolism as a consequence of applying sequential compression device on legs in a patient asymptomatic of deep vein thrombosis.
Anesthesiology Volume: 92 Page(s): 880 - 882
03/01/2000 Authors: Siddiqui AU; Buchman TG; Hotchkiss RS -
Invited commentary: fuzzy logic, clear reasoning.
Surgery Volume: 127 Page(s): 257
03/01/2000 Authors: Buchman T -
Molecular biology of multiple organ dysfunction syndrome: injury, adaptation, and apoptosis.
Surg Infect (Larchmt) Volume: 1 Page(s): 207 - 213
01/01/2000 Authors: Cobb JP; Buchman TG; Karl IE; Hotchkiss RS -
Caspases -2, -3, -6, and -9, but not caspase-1, are activated in sepsis-induced thymocyte apoptosis.
Shock Volume: 13 Page(s): 1 - 7
01/01/2000 Authors: Tinsley KW; Cheng SL; Buchman TG; Chang KC; Hui JJ; Swanson PE; Karl IE; Hotchkiss RS -
Prevention of lymphocyte cell death in sepsis improves survival in mice.
Proc Natl Acad Sci U S A Volume: 96 Page(s): 14541 - 14546
12/07/1999 Authors: Hotchkiss RS; Tinsley KW; Swanson PE; Chang KC; Cobb JP; Buchman TG; Korsmeyer SJ; Karl IE -
A meta-analysis of prospective randomized controlled studies comparing percutaneous and surgical tracheostomy
CRITICAL CARE MEDICINE Volume: 27 Page(s): A57 - A57
12/01/1999 Authors: Freeman BD; Isabella K; Lin N; Buchman TG -
Heart rate variability and length of stay in abdominal aortic surgery patients
Volume: 27 Page(s): A48 - A48
12/01/1999 Authors: Stein PK; Schmieg RE; El-Fouly A; Domitrovich PP; Buchman TG -
The abdominal compartment syndrome: CT findings.
AJR Am J Roentgenol Volume: 173 Page(s): 575 - 579
09/01/1999 Authors: Pickhardt PJ; Shimony JS; Heiken JP; Buchman TG; Fisher AJ -
Inducible nitric oxide synthase (iNOS) gene deficiency increases the mortality of sepsis in mice.
Surgery Volume: 126 Page(s): 438 - 442
08/01/1999 Authors: Cobb JP; Hotchkiss RS; Swanson PE; Chang K; Qiu Y; Laubach VE; Karl IE; Buchman TG -
Is heat shock protein-72 responsible for nitric oxide's ability to block stress-induced apoptosis?
Crit Care Med Volume: 27 Page(s): 1695
08/01/1999 Authors: Cobb JP; Qiu Y; Buchman TG -
Apoptotic cell death in patients with sepsis, shock, and multiple organ dysfunction.
Crit Care Med Volume: 27 Page(s): 1230 - 1251
07/01/1999 Authors: Hotchkiss RS; Swanson PE; Freeman BD; Tinsley KW; Cobb JP; Matuschak GM; Buchman TG; Karl IE -
Overexpression of Bcl-2 in transgenic mice decreases apoptosis and improves survival in sepsis.
J Immunol Volume: 162 Page(s): 4148 - 4156
04/01/1999 Authors: Hotchkiss RS; Swanson PE; Knudson CM; Chang KC; Cobb JP; Osborne DF; Zollner KM; Buchman TG; Korsmeyer SJ; Karl IE -
Identification of patient clusters using APACHE II parameters, and their correlation to outcomes
CRITICAL CARE MEDICINE Volume: 27 Page(s): A63 - A63
01/01/1999 Authors: Shannon W; Kollef M; Buchman T -
Iron-laden tissues sustain apoptosis following pyrexia.
Volume: 11 Page(s): 3 - 3
01/01/1999 Authors: Jacobs AK; Hotchkiss RS; Lin T; Swanson PS; Buchman TG -
iNOS gene deficiency decreases thymocyte apoptosis in septic mice.
Volume: 11 Page(s): 44 - 44
01/01/1999 Authors: Cobb JP; Hotchkiss RS; Swanson PE; Chang K; Qiu Y; Laubach VE; Buchman TG -
RFLP and linkage analysis of the porcine fibrinogen loci--FGA, FGB and FGG.
Anim Genet Volume: 29 Page(s): 471 - 472
12/01/1998 Authors: Archibald AL; Couperwhite S; Buchman TG -
Nitric oxide inhibits stress-induced endothelial cell apoptosis.
Crit Care Med Volume: 26 Page(s): 1500 - 1509
09/01/1998 Authors: DeMeester SL; Qiu Y; Buchman TG; Hotchkiss RS; Dunnigan K; Karl IE; Cobb JP -
Adenovirus-mediated inducible nitric oxide synthase gene transfer inhibits hepatocyte apoptosis.
Surgery Volume: 124 Page(s): 278 - 283
08/01/1998 Authors: Tzeng E; Billiar TR; Williams DL; Li J; Lizonova A; Kovesdi I; Kim YM -
Glutamine deprivation induces apoptosis in intestinal epithelial cells.
Surgery Volume: 124 Page(s): 152 - 159
08/01/1998 Authors: Papaconstantinou HT; Hwang KO; Rajaraman S; Hellmich MR; Townsend CM; Ko TC -
Stress-induced fractal rearrangement of the endothelial cell cytoskeleton causes apoptosis.
Surgery Volume: 124 Page(s): 362 - 371
08/01/1998 Authors: DeMeester SL; Cobb JP; Hotchkiss RS; Osborne DF; Karl IE; Tinsley KW; Buchman TG -
Illness severity adjustment for outcomes analysis: validation of the ICISS methodology in all 821,455 patients hospitalized in North Carolina in 1996.
Surgery Volume: 124 Page(s): 187 - 194
08/01/1998 Authors: Rutledge R; Osler T; Kromhout-Schiro S -
Differential effects of nitric oxide-mediated S-nitrosylation on p50 and c-jun DNA binding.
Surgery Volume: 124 Page(s): 137 - 141
08/01/1998 Authors: delaTorre A; Schroeder RA; Bartlett ST; Kuo PC -
Pyrrolidine dithiocarbamate activates the heat shock response and thereby induces apoptosis in primed endothelial cells.
Shock Volume: 10 Page(s): 1 - 6
07/01/1998 Authors: DeMeester SL; Buchman TG; Qiu Y; Dunnigan K; Hotchkiss RS; Karl IE; Cobb JP -
Expression of alpha2-macroglobulin by the interaction between hepatocytes and endothelial cells in coculture.
Am J Physiol Volume: 275 Page(s): R203 - R211
07/01/1998 Authors: Talamini MA; McCluskey MP; Buchman TG; De Maio A -
Improved clinical survival from sepsis.
J Am Coll Surg Volume: 186 Page(s): 350 - 351
03/01/1998 Authors: Freeman BD; Buchman TG -
Heat shock induces IkappaB-alpha and prevents stress-induced endothelial cell apoptosis.
Arch Surg Volume: 132 Page(s): 1283 - 1287
12/01/1997 Authors: DeMeester SL; Buchman TG; Qiu Y; Jacob AK; Dunnigan K; Hotchkiss RS; Karl I; Cobb JP -
Some like it hot.
Crit Care Med Volume: 25 Page(s): 1636
10/01/1997 Authors: Buchman TG -
Awash in data: the problem of predicting physiology in severe sepsis.
Shock Volume: 8 Page(s): 232
09/01/1997 Authors: Buchman TG -
Endothelial cell apoptosis is accelerated by inorganic iron and heat via an oxygen radical dependent mechanism.
Surgery Volume: 122 Page(s): 243 - 253
08/01/1997 Authors: Jacob AK; Hotchkiss RS; DeMeester SL; Hiramatsu M; Karl IE; Swanson PE; Cobb JP; Buchman TG -
Apoptosis in lymphoid and parenchymal cells during sepsis: findings in normal and T- and B-cell-deficient mice.
Crit Care Med Volume: 25 Page(s): 1298 - 1307
08/01/1997 Authors: Hotchkiss RS; Swanson PE; Cobb JP; Jacobson A; Buchman TG; Karl IE -
Cecal ligation and puncture (CLP) induces apoptosis in thymus, spleen, lung, and gut by an endotoxin and TNF-independent pathway.
Shock Volume: 7 Page(s): 247 - 253
04/01/1997 Authors: Hiramatsu M; Hotchkiss RS; Karl IE; Buchman TG -
Biological oscillators.
Crit Care Med Volume: 25 Page(s): 555
03/01/1997 Authors: Kleinman B -
Mechanism of immunosuppression in males following trauma-hemorrhage - Critical role of testosterone - Discussion - Invited commentary
ARCHIVES OF SURGERY Volume: 131 Page(s): 1192 - 1192
11/01/1996 Authors: Buchman TG -
Physiologic stability and physiologic state.
J Trauma Volume: 41 Page(s): 599 - 605
10/01/1996 Authors: Buchman TG -
Mechanisms of cell injury and death.
Br J Anaesth Volume: 77 Page(s): 3 - 10
07/01/1996 Authors: Cobb JP; Hotchkiss RS; Karl IE; Buchman TG -
Experimental human endotoxemia increases cardiac regularity: results from a prospective, randomized, crossover trial.
Crit Care Med Volume: 24 Page(s): 1117 - 1124
07/01/1996 Authors: Godin PJ; Fleisher LA; Eidsath A; Vandivier RW; Preas HL; Banks SM; Buchman TG; Suffredini AF -
Uncoupling of biological oscillators: a complementary hypothesis concerning the pathogenesis of multiple organ dysfunction syndrome.
Crit Care Med Volume: 24 Page(s): 1107 - 1116
07/01/1996 Authors: Godin PJ; Buchman TG -
Clinical molecular genetics and critical care medicine.
Crit Care Med Volume: 24 Page(s): 373 - 375
03/01/1996 Authors: Zehnbauer BA; Buchman TG -
The possible role of a central nervous system dopaminergic mechanism in hepatic c-fos protein expression following peritoneal sepsis.
Volume: 130 Page(s): 1209 - 1215
11/01/1995 Authors: Roy S; Charboneau R; Cain KJ; Chapin RB; Barke RA -
Hepatic heat shock and acute-phase gene expression are induced simultaneously after celiotomy in the anesthetized pig.
Anesthesiology Volume: 83 Page(s): 850 - 859
10/01/1995 Authors: Pannen BH; Maeda K; Ayuse T; Brienza N; Revelly JP; Robotham JL; Buchman TG -
Molecular biology in the intensive care unit: a framework for interpretation.
New Horiz Volume: 3 Page(s): 139 - 145
05/01/1995 Authors: Buchman TG; Zehnbauer BA -
Postoperative abdominal complications in cardiopulmonary bypass patients: a case-controlled study.
Ann Thorac Surg Volume: 59 Page(s): 1210 - 1213
05/01/1995 Authors: Ott MJ; Buchman TG; Baumgartner WA -
A HindIII RFLP at the porcine inter-alpha-trypsin inhibitor locus (ITIH).
Anim Genet Volume: 26 Page(s): 134
04/01/1995 Authors: Couperwhite S; Buchman TG; Archibald AL -
Computers in the intensive care unit: promises yet to be fulfilled.
J Intensive Care Med Volume: 10 Page(s): 234 - 240
01/01/1995 Authors: Buchman TG -
Endotoxin induces organ-specific endothelial cell injury.
Shock Volume: 3 Page(s): 46 - 50
01/01/1995 Authors: Maeda K; Abello PA; Abraham MR; Wetzel RC; Robotham JL; Buchman TG -
Macrophage endotoxin tolerance. Tumor necrosis factor and interleukin-1 regulation by lipopolysaccharide pretreatment.
Volume: 129 Page(s): 1263 - 1269
12/01/1994 Authors: Seatter SC; Bennet T; Li MH; Bubrick MP; West MA -
The role of programmed cell death (apoptosis) in thymic involution following sepsis.
Volume: 129 Page(s): 1256 - 1261
12/01/1994 Authors: Barke RA; Roy S; Chapin RB; Charboneau R -
Radiodetoxified endotoxin-induced tolerance alters monocyte but not neutrophil CD11b and CD18 expression in response to lipopolysaccharide.
Arch Surg Volume: 129 Page(s): 1153 - 1158
11/01/1994 Authors: Connall TP; Zhang J; Vaziri ND; Schwartz RJ; Kaupke CJ; Oveisi F; Wilson SE -
Heat shock-induced cell death in murine microvascular endothelial cells depends on priming with tumor necrosis factor-alpha or interferon-gamma.
Shock Volume: 2 Page(s): 320 - 323
11/01/1994 Authors: Abello PA; Buchman TG -
ANESTHESIA AND SURGERY LEAD TO AN ACCUMULATION OF HEAT-SHOCK PROTEIN 72 MESSENGER-RNA IN THE LIVER WITHOUT INCREASING HEAT-SHOCK PROTEIN 72 GENE-TRANSCRIPTION
Volume: 81 Page(s): A280 - A280
09/01/1994 Authors: PANNEN BHJ; MAEDA K; AYUSE T; BRIENZA N; REVELLY JP; BUCHMAN TG; ROBOTHAM JL -
Trauma team activation for 'mechanism of injury' blunt trauma victims: time for a change?
Volume: 37 Page(s): 275 - 281
08/01/1994 Authors: Shatney CH; Sensaki K -
Rapid detection and identification of Candida albicans and Torulopsis (Candida) glabrata in clinical specimens by species-specific nested PCR amplification of a cytochrome P-450 lanosterol-alpha-demethylase (L1A1) gene fragment.
J Clin Microbiol Volume: 32 Page(s): 1902 - 1907
08/01/1994 Authors: Burgener-Kairuz P; Zuber JP; Jaunin P; Buchman TG; Bille J; Rossier M -
Thiol reducing agents modulate induced apoptosis in porcine endothelial cells.
Shock Volume: 2 Page(s): 79 - 83
08/01/1994 Authors: Abello PA; Fidler SA; Buchman TG -
Elevated levels of soluble ICAM-1 correlate with the development of multiple organ failure in severely injured trauma patients.
J Trauma Volume: 37 Page(s): 100 - 109
07/01/1994 Authors: Law MM; Cryer HG; Abraham E -
Manipulation of stress gene expression: a novel therapy for the treatment of sepsis?
Crit Care Med Volume: 22 Page(s): 901 - 903
06/01/1994 Authors: Buchman TG -
A comparison of statistical and connectionist models for the prediction of chronicity in a surgical intensive care unit.
Crit Care Med Volume: 22 Page(s): 750 - 762
05/01/1994 Authors: Buchman TG; Kubos KL; Seidler AJ; Siegforth MJ -
GUT EPITHELIAL APOPTOSIS IS ENHANCED BY HEMORRHAGIC-SHOCK RESUSCITATION
Volume: 106 Page(s): A218 - A218
04/01/1994 Authors: ABELLO PA; MAYUMI T; TURNER DJ; CHAN C; BULKLEY GB; BUCHMAN TG -
Differential induction of nitric oxide synthase in hepatocytes during endotoxemia and the acute-phase response.
Arch Surg Volume: 129 Page(s): 165 - 171
02/01/1994 Authors: Geller DA; Freeswick PD; Nguyen D; Nussler AK; Di Silvio M; Shapiro RA; Wang SC; Simmons RL; Billiar TR -
Limited role of barium enema examination preceding colostomy closure in trauma patients.
J Trauma Volume: 36 Page(s): 245 - 246
02/01/1994 Authors: Sola JE; Buchman TG; Bender JS -
Antioxidants modulate induction of programmed endothelial cell death (apoptosis) by endotoxin.
Arch Surg Volume: 129 Page(s): 134 - 140
02/01/1994 Authors: Abello PA; Fidler SA; Bulkley GB; Buchman TG -
Shock and multiple organ failure.
Volume: 366 Page(s): 253 - 268
01/01/1994 Authors: Abello PA; Buchman TG; Bulkley GB -
Induction of heat-shock gene expression in postischemic pig liver depends on superoxide generation.
Gastroenterology Volume: 106 Page(s): 177 - 184
01/01/1994 Authors: Schoeniger LO; Andreoni KA; Ott GR; Risby TH; Bulkley GB; Udelsman R; Burdick JF; Buchman TG -
Myocardial heat shock gene expression in pigs is dependent on superoxide anion generated at reperfusion.
Shock Volume: 1 Page(s): 31 - 35
01/01/1994 Authors: Schoeniger LO; Curtis W; Esnaola NF; Beck SC; Gardner T; Buchman TG -
Regulation of acute phase gene expression following surgery and endotoxin administration in the anesthetized pig.
Anesthesiology Volume: 79 Page(s): 1324 - 1337
12/01/1993 Authors: Maeda K; Schoeniger LO; Shimada M; Winchurch RA; Buchman TG; Robotham JL -
Determinants of catecholamine and cortisol responses to lower extremity revascularization. The PIRAT Study Group.
Anesthesiology Volume: 79 Page(s): 1202 - 1209
12/01/1993 Authors: Breslow MJ; Parker SD; Frank SM; Norris EJ; Yates H; Raff H; Rock P; Christopherson R; Rosenfeld BA; Beattie C -
Undergraduate critical care education.
Crit Care Med Volume: 21 Page(s): 1977 - 1978
12/01/1993 Authors: Hassan E; Roffman DS -
Induction of translational thermotolerance in liver of thermally stressed rats.
Eur J Biochem Volume: 218 Page(s): 413 - 420
12/01/1993 Authors: De Maio A; Beck SC; Buchman TG -
Perioperative morbidity in patients randomized to epidural or general anesthesia for lower extremity vascular surgery. Perioperative Ischemia Randomized Anesthesia Trial Study Group.
Anesthesiology Volume: 79 Page(s): 422 - 434
09/01/1993 Authors: Christopherson R; Beattie C; Frank SM; Norris EJ; Meinert CL; Gottlieb SO; Yates H; Rock P; Parker SD; Perler BA -
The effects of different anesthetic regimens on fibrinolysis and the development of postoperative arterial thrombosis. Perioperative Ischemia Randomized Anesthesia Trial Study Group.
Anesthesiology Volume: 79 Page(s): 435 - 443
09/01/1993 Authors: Rosenfeld BA; Beattie C; Christopherson R; Norris EJ; Frank SM; Breslow MJ; Rock P; Parker SD; Gottlieb SO; Perler BA -
Morbidity and timing of colostomy closure in trauma patients.
Injury Volume: 24 Page(s): 438 - 440
08/01/1993 Authors: Sola JE; Bender JS; Buchman TG -
Mechanisms of cytokine cascade activation in patients with sepsis: normal cytokine transcription despite reduced CD14 receptor expression.
Volume: 114 Page(s): 243 - 250
08/01/1993 Authors: Ertel W; Krombach F; Kremer JP; Jarrar D; Thiele V; Eymann J; Muenzing S; Faist E; Messmer K; Schildberg FW -
The effects of CO2 pneumoperitoneum on hemodynamics in hemorrhaged animals.
Surgery Volume: 114 Page(s): 381 - 387
08/01/1993 Authors: Ho HS; Saunders CJ; Corso FA; Wolfe BM -
Cytokine induction of interferon regulatory factor-1 in hepatocytes.
Surgery Volume: 114 Page(s): 235 - 242
08/01/1993 Authors: Geller DA; Nguyen D; Shapiro RA; Nussler A; Di Silvio M; Freeswick P; Wang SC; Tweardy DJ; Simmons RL; Billiar TR -
Sepsis-induced alterations in phosphoenolpyruvate carboxykinase expression: the role of insulin and glucagon.
Circ Shock Volume: 40 Page(s): 295 - 302
08/01/1993 Authors: Deutschman CS; De Maio A; Buchman TG; Clemens MG -
Antisense oligodeoxynucleotide to inducible nitric oxide synthase inhibits nitric oxide synthesis in rat pulmonary artery smooth muscle cells in culture.
Surgery Volume: 114 Page(s): 272 - 277
08/01/1993 Authors: Thomae KR; Geller DA; Billiar TR; Davies P; Pitt BR; Simmons RL; Nakayama DK -
Induction of heat shock response leads to apoptosis in endothelial cells previously exposed to endotoxin.
Am J Physiol Volume: 265 Page(s): H165 - H170
07/01/1993 Authors: Buchman TG; Abello PA; Smith EH; Bulkley GB -
Heat shock gene expression and development of translational thermotolerance in human hepatoblastoma cells.
Circ Shock Volume: 40 Page(s): 177 - 186
07/01/1993 Authors: De Maio A; Beck SC; Buchman TG -
Unintentional hypothermia is associated with postoperative myocardial ischemia. The Perioperative Ischemia Randomized Anesthesia Trial Study Group.
Anesthesiology Volume: 78 Page(s): 468 - 476
03/01/1993 Authors: Frank SM; Beattie C; Christopherson R; Norris EJ; Perler BA; Williams GM; Gottlieb SO -
A reversibly palmitoylated resident protein (p63) of an ER-Golgi intermediate compartment is related to a circulatory shock resuscitation protein.
J Cell Sci Volume: 104 ( Pt 3) Page(s): 685 - 694
03/01/1993 Authors: Schweizer A; Rohrer J; Jen P; DeMaio A; Buchman TG; Hauri HP -
MECHANISM OF INDUCED CYTOPROTECTION BY HEAT-SHOCK PROTEINS
Volume: 7 Page(s): A138 - A138
02/19/1993 Authors: BECK SC; BUCHMAN TG; DEMAIO A -
Multiple organ failure.
Curr Opin Gen Surg Page(s): 26 - 31
01/01/1993 Authors: Buchman TG -
Optimizing prehospital triage criteria for trauma team alerts.
J Trauma Volume: 34 Page(s): 127 - 132
01/01/1993 Authors: Phillips JA; Buchman TG -
Substance abuse-related admissions to adult intensive care.
Chest Volume: 103 Page(s): 21 - 25
01/01/1993 Authors: Baldwin WA; Rosenfeld BA; Breslow MJ; Buchman TG; Deutschman CS; Moore RD -
Undergraduate education in critical care medicine.
Crit Care Med Volume: 20 Page(s): 1595 - 1603
11/01/1992 Authors: Buchman TG; Dellinger RP; Raphaely RC; Todres ID -
SYSTEMIC INFLAMMATION DOWN-REGULATES STEADY-STATE MESSENGER-RNA LEVELS CODING FOR THE MAJOR HEPATIC GAP JUNCTION PROTEIN CONNEXIN-32
Volume: 16 Page(s): A99 - A99
10/01/1992 Authors: CLEMENS M; WANG K; BUCHMAN T; DEMAIO A -
DEVELOPMENT OF TRANSLATIONAL THERMOTOLERANCE IN THE LIVER OF STRESSED RATS
Volume: 16 Page(s): A160 - A160
10/01/1992 Authors: DEMAIO A; BECK SC; BUCHMAN TG -
Heat-shock gene expression excludes hepatic acute-phase gene expression after resuscitation from hemorrhagic shock.
Surgery Volume: 112 Page(s): 355 - 362
08/01/1992 Authors: Schoeniger LO; Reilly PM; Bulkley GB; Buchman TG -
MOLECULAR-BIOLOGY OF CIRCULATORY SHOCK .5. HEAT-SHOCK GENE-EXPRESSION EXCLUDES HEPATIC ACUTE-PHASE GENE-EXPRESSION AFTER RESUSCITATION FROM HEMORRHAGIC-SHOCK
Volume: 112 Page(s): 355 - 363
08/01/1992 Authors: SCHOENIGER LO; REILLY PM; BULKLEY GB; BUCHMAN TG -
The prevalence of hepatitis C in a regional level I trauma center population.
J Trauma Volume: 33 Page(s): 126 - 128
07/01/1992 Authors: Kaplan AJ; Zone-Smith LK; Hannegan C; Norcross ED -
Recognition, resuscitation and management of patients with penetrating cardiac injuries.
Surg Gynecol Obstet Volume: 174 Page(s): 205 - 210
03/01/1992 Authors: Buchman TG; Phillips J; Menker JB -
COMPETITION FOR STRESS GENE-EXPRESSION INDUCES ENDOTHELIAL-CELL APOPTOSIS (PROGRAMMED CELL-DEATH) INVITRO
Volume: 6 Page(s): A2071 - A2071
02/28/1992 Authors: BUCHMAN T; SMITH E; BULKLEY G -
The role of anesthetic induction agents and neuromuscular blockade in the endotracheal intubation of trauma victims.
Surg Gynecol Obstet Volume: 173 Page(s): 477 - 481
12/01/1991 Authors: Ligier B; Buchman TG; Breslow MJ; Deutschman CS -
Trauma during pregnancy. A review of 79 cases.
Arch Surg Volume: 126 Page(s): 1073 - 1078
09/01/1991 Authors: Esposito TJ; Gens DR; Smith LG; Scorpio R; Buchman T -
Molecular biology of circulatory shock: IV. Translation and secretion of HEP G2 cell proteins are independently attenuated during heat shock.
Volume: 34 Page(s): 329 - 335
07/01/1991 Authors: De Maio A; Buchman TG -
Who should care for the SICU patient?
Arch Surg Volume: 126 Page(s): 398
03/01/1991 Authors: Buchman TG -
Strategies for trauma resuscitation.
Surg Gynecol Obstet Volume: 172 Page(s): 8 - 12
01/01/1991 Authors: Buchman TG; Menker JB; Lipsett PA -
Gastrointestinal complications in heart and in heart-lung transplant patients.
J Heart Lung Transplant Volume: 10 Page(s): 547 - 555
01/01/1991 Authors: Augustine SM; Yeo CJ; Buchman TG; Achuff SC; Baumgartner WA -
Mammalian liver contains an activity which mimics bacterial chloramphenicol acetyltransferase.
Biochim Biophys Acta Volume: 1087 Page(s): 303 - 308
11/30/1990 Authors: De Maio A; Buchman TG -
Molecular biology of circulatory shock. Part III. Human hepatoblastoma (HepG2) cells demonstrate two patterns of shock-induced gene expression that are independent, exclusive, and prioritized.
Surgery Volume: 108 Page(s): 902 - 912
11/01/1990 Authors: Cabin DE; Buchman TG -
Molecular biology of circulatory shock. Part II. Expression of four groups of hepatic genes is enhanced after resuscitation from cardiogenic shock.
Surgery Volume: 108 Page(s): 559 - 566
09/01/1990 Authors: Buchman TG; Cabin DE; Vickers S; Deutschman CS; Delgado E; Sussman MM; Bulkley GB -
Detection of surgical pathogens by in vitro DNA amplification. Part I. Rapid identification of Candida albicans by in vitro amplification of a fungus-specific gene.
Volume: 108 Page(s): 338 - 346
08/01/1990 Authors: Buchman TG; Rossier M; Merz WG; Charache P -
Change in hepatic gene expression after shock/resuscitation.
Surgery Volume: 106 Page(s): 283 - 290
08/01/1989 Authors: Buchman TG; Cabin DE; Porter JM; Bulkley GB -
HYPOXIA-REOXYGENATION INDUCED CHANGES IN HEP G2 CELL GENE-EXPRESSION ARE MODULATED BY DRUGS WHICH INHIBIT GENERATION OF OXYGEN FREE-RADICALS
CIRCULATORY SHOCK Volume: 24 Page(s): 258 - 258
04/01/1988 Authors: BUCHMAN TG; CABIN D; BULKLEY GB -
Current management of patients with lower gastrointestinal bleeding.
Surg Clin North Am Volume: 67 Page(s): 651 - 664
06/01/1987 Authors: Buchman TG; Bulkley GB -
Reasons for delay of the diagnosis of acute appendicitis.
Surg Gynecol Obstet Volume: 158 Page(s): 260 - 266
03/01/1984 Authors: Buchman TG; Zuidema GD -
The role of computerized tomographic scanning in the surgical management of pyogenic hepatic abscess.
Surg Gynecol Obstet Volume: 153 Page(s): 1 - 9
07/01/1981 Authors: Buchman TG; Zuidema GD -
Nosocomial herpetic infections in a pediatric intensive care unit.
Am J Epidemiol Volume: 113 Page(s): 126 - 132
02/01/1981 Authors: Adams G; Stover BH; Keenlyside RA; Hooton TM; Buchman TG; Roizman B; Stewart JA -
Temporal cluster of herpes simplex encephalitis: investigation by restriction endonuclease cleavage of viral DNA.
J Infect Dis Volume: 141 Page(s): 436 - 440
04/01/1980 Authors: Hammer SM; Buchman TG; D'Angelo LJ; Karchmer AW; Roizman B; Hirsch MS -
The structure of herpes simplex virus DNA and its application to molecular epidemiology.
Ann N Y Acad Sci Volume: 354 Page(s): 279 - 290
01/01/1980 Authors: Buchman TG; Simpson T; Nosal C; Roizman B; Nahmias AJ -
Demonstration of exogenous genital reinfection with herpes simplex virus type 2 by restriction endonuclease fingerprinting of viral DNA.
J Infect Dis Volume: 140 Page(s): 295 - 304
09/01/1979 Authors: Buchman TG; Roizman B; Nahmias AJ -
The molecular epidemiology of herpes simplex viruses.
Hosp Pract Volume: 14 Page(s): 95 - 104
01/01/1979 Authors: Roizman B; Buchman T -
Restriction endonuclease fingerprinting of herpes simplex virus DNA: a novel epidemiological tool applied to a nosocomial outbreak.
J Infect Dis Volume: 138 Page(s): 488 - 498
10/01/1978 Authors: Buchman TG; Roizman B; Adams G; Stover BH -
Anatomy of bovine mammillitis DNA II. Size and arrangements of the deoxynucleotide sequences.
J Virol Volume: 27 Page(s): 239 - 254
07/01/1978 Authors: Buchman TG; Roizman B -
Transmission of herpes-simplex virus type 1 in a nursery for the newborn. Identification of viral isolates by D.N.A. "fingerprinting".
Lancet Volume: 1 Page(s): 964 - 966
05/06/1978 Authors: Linnemann CC; Buchman TG; Light IJ; Ballard JL -
Anatomy of bovine mammillitis DNA. I Restriction endonuclease maps of four populations of molecules that differ in the relative orientation of their long and short components.
J Virol Volume: 25 Page(s): 395 - 407
01/01/1978 Authors: Buchman TG; Roizman B -
Anatomy of herpes simplex virus DNA. IX. Apparent exclusion of some parental DNA arrangements in the generation of intertypic (HSV-1 X HSV-2) recombinants.
J Virol Volume: 24 Page(s): 231 - 248
10/01/1977 Authors: Morse LS; Buchman TG; Roizman B; Schaffer PA