Publications

• High-throughput quantitation of human neutrophil recruitment and functional responses in an air-blood barrier array.
  APL Bioeng Volume: 9 Page(s): 026110
  06/01/2025 Authors: Viola H; Chen L-H; Jo S; Washington K; Selva C; Li A; Feng D; Giacalone V; Stephenson ST; Cottrill K
• A Mimetic Assay of Neutrophil Extracellular Trap Degradation Using YOYO-1-Stained DNA-Histone Surface Webs.
  Cells Volume: 14
  04/19/2025 Authors: Nguyen KH; Wasielewski ML; Yalavarthi S; Qu X; Knight JS; Takayama S
• Bioprinted Micro-Clots for Kinetic Analysis of Endothelial Cell-Mediated Fibrinolysis.
  Adv Healthc Mater Volume: 14 Page(s): e2403043
  03/01/2025 Authors: Chang JJ; Brew K; Hamilton JAG; Kumar V; Diaz JA; Takayama S
• Caki-1 Spheroids as a Renal Model for Studying Free Fatty Acid-Induced Lipotoxicity.
  Cells Volume: 14
  02/27/2025 Authors: Battle D; Qiu X; Alex M; Rivers L; Hamilton JAG; Takayama S; Zhao X
• The Spheroid Light Microscopy Image Atlas for morphometrical analysis of three-dimensional cell cultures.
  Sci Data Volume: 12 Page(s): 283
  02/17/2025 Authors: Blondeel E; Peirsman A; Vermeulen S; Piccinini F; De Vuyst F; Estvo D; Al-Jamei S; Bedeschi M; Castellani G; Cruz T
• Controlled Dynamic Microfluidic Culture of Murine, Bovine, and Human Embryos Improves Development: Proof-of-Concept Studies.
  Cells Volume: 13
  12/17/2024 Authors: Alegretti JR; Rocha AMD; Nogueira-de-Souza NC; Kato N; Barros BC; Motta ELA; Serafini PC; Takayama S; Smith GD
• A closed-loop modular multiorgan-on-chips platform for self-sustaining and tightly controlled oxygenation.
  Proc Natl Acad Sci U S A Volume: 121 Page(s): e2413684121
  11/19/2024 Authors: Jiang N; Ying G; Yin Y; Guo J; Lozada J; Valdivia Padilla A; Gmez A; Gomes de Melo BA; Lugo Mestre F; Gansevoort M
• Forced air oscillations - pneumatic capacitance in microfluidic oscillators produces non-linear responses and emergent behaviors.
  Lab Chip Volume: 24 Page(s): 4798 - 4807
  10/09/2024 Authors: Lesher-Prez SC; Vasani V; So J; Takayama S
• Development of robust antiviral assays using relevant apical-out human airway organoids.
  bioRxiv
  07/12/2024 Authors: Lee J-H; LeCher JC; Parigoris E; Shinagawa N; Sentosa J; Manfredi C; Goh SL; De R; Tao S; Zandi K
• HIGH THROUGHPUT QUANTITATION OF HUMAN NEUTROPHIL RECRUITMENT AND FUNCTIONAL RESPONSES IN AN AIR-BLOOD BARRIER ARRAY.
  bioRxiv
  05/14/2024 Authors: Viola H; Chen L-H; Jo S; Washington K; Selva C; Li A; Feng D; Giacalone V; Stephenson ST; Cottrill K
• Liquid plug propagation in computer-controlled microfluidic airway-on-a-chip with semi-circular microchannels.
  Lab Chip Volume: 24 Page(s): 197 - 209
  01/17/2024 Authors: Viola HL; Vasani V; Washington K; Lee J-H; Selva C; Li A; Llorente CJ; Murayama Y; Grotberg JB; Roman F
• OctoShaker: A versatile robotic biomechanical agitator for cellular and organoid research.
  Rev Sci Instrum Volume: 94
  12/01/2023 Authors: Huang Y; Lee S; Liu W; Takayama S; Jia S
• Super-resolution imaging of linearized chromatin in tunable nanochannels.
  Nanoscale Horiz Volume: 8 Page(s): 1043 - 1053
  07/24/2023 Authors: Lee J-H; Chiu JH-C; Ginga NJ; Ahmed T; Thouless MD; Liu Y; Takayama S
• Liquid plug propagation in computer-controlled microfluidic airway-on-a-chip with semi-circular microchannels.
  bioRxiv
  05/25/2023 Authors: Viola HL; Vasani V; Washington K; Lee J-H; Selva C; Li A; Llorente CJ; Murayama Y; Grotberg JB; Roman F
• Synthetic neutrophil extracellular traps dissect bactericidal contribution of NETs under regulation of -1-antitrypsin.
  Sci Adv Volume: 9 Page(s): eadf2445
  04/28/2023 Authors: Yang T; Yu J; Ahmed T; Nguyen K; Nie F; Zan R; Li Z; Han P; Shen H; Zhang X
• Triple-negative breast cancer cells invade adipocyte/preadipocyte-encapsulating geometrically inverted mammary organoids.
  Integr Biol (Camb) Volume: 15
  04/11/2023 Authors: Mertz DR; Parigoris E; Sentosa J; Lee J-H; Lee S; Kleer CG; Luker G; Takayama S
• Manipulation of the nucleoscaffold potentiates cellular reprogramming kinetics.
  bioRxiv
  03/13/2023 Authors: Yang BA; da Rocha AM; Newton I; Shcherbina A; Wong S-W; Fraczek PM; Larouche JA; Hiraki HL; Baker BM; Shin J-W
• Visualization of Nuclease- and Serum-Mediated Chromatin Degradation with DNA-Histone Mesostructures.
  Int J Mol Sci Volume: 24
  02/06/2023 Authors: Wasielewski ML; Nguyen K; Yalavarthi S; Ekbote P; Weerappuli PD; Knight JS; Takayama S
• 3D super-resolution live-cell imaging with radial symmetry and Fourier light-field microscopy.
  Biomed Opt Express Volume: 13 Page(s): 5574 - 5584
  11/01/2022 Authors: Han K; Hua X; Vasani V; Kim G-AR; Liu W; Takayama S; Jia S
• Extended longevity geometrically-inverted proximal tubule organoids.
  Biomaterials Volume: 290 Page(s): 121828
  11/01/2022 Authors: Parigoris E; Lee J-H; Liu AY; Zhao X; Takayama S
• Nucleic acid partitioning in PEG-Ficoll protocells.
  J Chem Eng Data Volume: 67 Page(s): 1964 - 1971
  08/11/2022 Authors: Ahmed T; Zhang Y; Lee J-H; Styczynski MP; Takayama S
• Fourier light-field imaging of human organoids with a hybrid point-spread function.
  Biosens Bioelectron Volume: 208 Page(s): 114201
  07/15/2022 Authors: Liu W; Kim G-AR; Takayama S; Jia S
• Contracting scars from fibrin drops.
  Integr Biol (Camb) Volume: 14 Page(s): 1 - 12
  03/21/2022 Authors: Robinson S; Parigoris E; Chang J; Hecker L; Takayama S
• Perfusion System for Modification of Luminal Contents of Human Intestinal Organoids and Realtime Imaging Analysis of Microbial Populations.
  Micromachines (Basel) Volume: 13
  01/14/2022 Authors: Ginga NJ; Slyman R; Kim G-A; Parigoris E; Huang S; Yadagiri VK; Young VB; Spence JR; Takayama S
• High-throughput formation and image-based analysis of basal-in mammary organoids in 384-well plates.
  Sci Rep Volume: 12 Page(s): 317
  01/10/2022 Authors: Lee S; Chang J; Kang S-M; Parigoris E; Lee J-H; Huh YS; Takayama S
• A High-Throughput Distal Lung Air-Blood Barrier Model Enabled By Density-Driven Underside Epithelium Seeding.
  Adv Healthc Mater Volume: 11 Page(s): e2102450
  01/01/2022 Authors: Viola H; Washington K; Selva C; Grunwell J; Tirouvanziam R; Takayama S
• MISpheroID: a knowledgebase and transparency tool for minimum information in spheroid identity.
  Nat Methods Volume: 18 Page(s): 1294 - 1303
  11/01/2021 Authors: Peirsman A; Blondeel E; Ahmed T; Anckaert J; Audenaert D; Boterberg T; Buzas K; Carragher N; Castellani G; Castro F
• Protocell arrays for simultaneous detection of diverse analytes.
  Nat Commun Volume: 12 Page(s): 5724
  09/29/2021 Authors: Zhang Y; Kojima T; Kim G-A; McNerney MP; Takayama S; Styczynski MP
• Dosage-dependent antimicrobial activity of DNA-histone microwebs against Staphylococcus aureus.
  Adv Mater Interfaces Volume: 8
  09/09/2021 Authors: Yang T; Yang S; Ahmed T; Nguyen K; Yu J; Cao X; Zan R; Zhang X; Shen H; Fay ME
• A High-Throughput Distal Lung Air-Blood Barrier Model Enabled By Density-Driven Underside Epithelium Seeding.
  Adv Healthc Mater Volume: 10 Page(s): e2100879
  08/01/2021 Authors: Viola H; Washington K; Selva C; Grunwell J; Tirouvanziam R; Takayama S
• Aqueous Two-Phase Systems and Microfluidics for Microscale Assays and Analytical Measurements.
  Annu Rev Anal Chem (Palo Alto Calif) Volume: 14 Page(s): 231 - 255
  07/27/2021 Authors: Ahmed T; Yamanishi C; Kojima T; Takayama S
• Alginate Microencapsulation for Three-Dimensional In Vitro Cell Culture.
  ACS Biomater Sci Eng Volume: 7 Page(s): 2864 - 2879
  07/12/2021 Authors: Kang S-M; Lee J-H; Huh YS; Takayama S
• Aqueous two-phase deposition and fibrinolysis of fibroblast-laden fibrin micro-scaffolds.
  Biofabrication Volume: 13
  04/07/2021 Authors: Robinson S; Chang J; Parigoris E; Hecker L; Takayama S
• Cancer Cell Invasion of Mammary Organoids with Basal-In Phenotype.
  Adv Healthc Mater Volume: 10 Page(s): e2000810
  02/01/2021 Authors: Parigoris E; Lee S; Mertz D; Turner M; Liu AY; Sentosa J; Djomehri S; Chang HC; Luker K; Luker G
• Cell-morphodynamic phenotype classification with application to cancer metastasis using cell magnetorotation and machine-learning.
  PLoS One Volume: 16 Page(s): e0259462
  01/01/2021 Authors: Elbez R; Folz J; McLean A; Roca H; Labuz JM; Pienta KJ; Takayama S; Kopelman R
• Engineered Microsystems for Spheroid and Organoid Studies.
  Adv Healthc Mater Volume: 10 Page(s): e2001284
  01/01/2021 Authors: Kang S-M; Kim D; Lee J-H; Takayama S; Park JY
• Studying Adipose Tissue in the Breast Tumor Microenvironment In Vitro: Progress and Opportunities.
  Tissue Eng Regen Med Volume: 17 Page(s): 773 - 785
  12/01/2020 Authors: Mertz D; Sentosa J; Luker G; Takayama S
• One-incubation one-hour multiplex ELISA enabled by aqueous two-phase systems.
  Analyst Volume: 145 Page(s): 3517 - 3527
  05/18/2020 Authors: Tongdee M; Yamanishi C; Maeda M; Kojima T; Dishinger J; Chantiwas R; Takayama S
• Kinetic Analysis of Label-Free Microscale Collagen Gel Contraction Using Machine Learning-Aided Image Analysis.
  Front Bioeng Biotechnol Volume: 8 Page(s): 582602
  01/01/2020 Authors: Yamanishi C; Parigoris E; Takayama S
• Microphysiological systems modeling acute respiratory distress syndrome that capture mechanical force-induced injury-inflammation-repair.
  APL Bioeng Volume: 3 Page(s): 041503
  12/01/2019 Authors: Viola H; Chang J; Grunwell JR; Hecker L; Tirouvanziam R; Grotberg JB; Takayama S
• Extracellular Trap-Mimicking DNA-Histone Mesostructures Synergistically Activate Dendritic Cells.
  Adv Healthc Mater Volume: 8 Page(s): e1900926
  11/01/2019 Authors: Weerappuli PD; Louttit C; Kojima T; Brennan L; Yalavarthi S; Xu Y; Ochyl LJ; Maeda ML; Kim HS; Knight JS
• Biofabrication of phenotypic pulmonary fibrosis assays.
  Biofabrication Volume: 11 Page(s): 032005
  06/19/2019 Authors: Yamanishi C; Robinson S; Takayama S
• Antimicrobial Microwebs of DNA-Histone Inspired from Neutrophil Extracellular Traps.
  Adv Mater Volume: 31 Page(s): e1807436
  04/01/2019 Authors: Song Y; Kadiyala U; Weerappuli P; Valdez JJ; Yalavarthi S; Louttit C; Knight JS; Moon JJ; Weiss DS; VanEpps JS
• A platform for artificial intelligence based identification of the extravasation potential of cancer cells into the brain metastatic niche.
  Lab Chip Volume: 19 Page(s): 1162 - 1173
  03/27/2019 Authors: Oliver CR; Altemus MA; Westerhof TM; Cheriyan H; Cheng X; Dziubinski M; Wu Z; Yates J; Morikawa A; Heth J
• A Two-Pulse Cellular Stimulation Test Elucidates Variability and Mechanisms in Signaling Pathways.
  Biophys J Volume: 116 Page(s): 962 - 973
  03/05/2019 Authors: Sumit M; Jovic A; Neubig RR; Takayama S; Linderman JJ
• A reproducible scaffold-free 3D organoid model to study neoplastic progression in breast cancer.
  J Cell Commun Signal Volume: 13 Page(s): 129 - 143
  03/01/2019 Authors: Djomehri SI; Burman B; Gonzalez ME; Takayama S; Kleer CG
• Nonadhesive Alginate Hydrogels Support Growth of Pluripotent Stem Cell-Derived Intestinal Organoids.
  Stem Cell Reports Volume: 12 Page(s): 381 - 394
  02/12/2019 Authors: Capeling MM; Czerwinski M; Huang S; Tsai Y-H; Wu A; Nagy MS; Juliar B; Sundaram N; Song Y; Han WM
• DNA-Based Biomaterials for Immunoengineering.
  Adv Healthc Mater Volume: 8 Page(s): e1801243
  02/01/2019 Authors: Maeda M; Kojima T; Song Y; Takayama S
• Rapid translocation of pluripotency-related transcription factors by external uniaxial forces.
  Integr Biol (Camb) Volume: 11 Page(s): 41 - 52
  02/01/2019 Authors: Topal T; Kim BC; Villa-Diaz LG; Deng CX; Takayama S; Krebsbach PH
• Determination of Aqueous Two-Phase System Binodals and Tie-Lines by Electrowetting-on-Dielectric Droplet Manipulation.
  Chembiochem Volume: 20 Page(s): 270 - 275
  01/18/2019 Authors: Kojima T; Lin C-C; Takayama S; Fan S-K
• Dispersible hydrogel force sensors reveal patterns of solid mechanical stress in multicellular spheroid cultures.
  Nat Commun Volume: 10 Page(s): 144
  01/11/2019 Authors: Lee W; Kalashnikov N; Mok S; Halaoui R; Kuzmin E; Putnam AJ; Takayama S; Park M; McCaffrey L; Zhao R
• Stigmatic Microscopy Enables Low-Cost, 3D, Microscale Particle Imaging Velocimetry in Rehydrating Aqueous Two-Phase Systems.
  Front Chem Volume: 7 Page(s): 311
  01/01/2019 Authors: Yamanishi C; Oliver CR; Kojima T; Takayama S
• Perspective: The promise of multi-cellular engineered living systems.
  APL Bioeng Volume: 2 Page(s): 040901
  12/01/2018 Authors: Kamm RD; Bashir R; Arora N; Dar RD; Gillette MU; Griffith LG; Kemp ML; Kinlaw K; Levin M; Martin AC
• Studying the Cost and Effectiveness of OSS Quality Assessment Models: An Experience Report of Fujitsu QNET
  IEICE TRANSACTIONS ON INFORMATION AND SYSTEMS Volume: E101D Page(s): 2744 - 2753
  11/01/2018 Authors: Kamei Y; Matsumoto T; Yamashita K; Ubayashi N; Iwasaki T; Takayama S
• A Scaffold-Free 3D Organoid Model to Study Neoplastic Progression in Breast Cancer
  Volume: 188 Page(s): 2412 - 2412
  10/01/2018 Authors: Djomehri S; Takayama S; Kleer C
• Membraneless Compartmentalization Facilitates Enzymatic Cascade Reactions and Reduces Substrate Inhibition.
  ACS Appl Mater Interfaces Volume: 10 Page(s): 32782 - 32791
  09/26/2018 Authors: Kojima T; Takayama S
• Engineering cell heterogeneity into organs-on-a-chip.
  Lab Chip Volume: 18 Page(s): 2378 - 2395
  08/07/2018 Authors: Mertz DR; Ahmed T; Takayama S
• A scaffold-free 3D organoid model to study neoplastic progression in breast cancer
  Volume: 78
  07/01/2018 Authors: Djomehri S; Takayama S; Kleer C
• Analysis of breast cancer lines and PDXs using a blood brain niche (mu m-BBN) microfluidic device and algorithms to aid diagnosis of brain metastatic potential
  Volume: 78
  07/01/2018 Authors: Oliver CR; Altemus M; Westerhof T; Morikawa A; Cheng X; Heth J; Takayama S; Castro M; Merajver S
• Budding-like division of all-aqueous emulsion droplets modulated by networks of protein nanofibrils.
  Nat Commun Volume: 9 Page(s): 2110
  05/29/2018 Authors: Song Y; Michaels TCT; Ma Q; Liu Z; Yuan H; Takayama S; Knowles TPJ; Shum HC
• Capacitive coupling synchronizes autonomous microfluidic oscillators.
  Electrophoresis Volume: 39 Page(s): 1096 - 1103
  04/01/2018 Authors: Lesher-Prez SC; Zhang C; Takayama S
• DETERMINING THE MECHANISMS BEHIND DISTRIBUTION VARIABILITY IN SMALL MOLECULE PHARMACEUTICALS USING 3D SPHEROID TISSUES
  Volume: 33 Page(s): S67 - S67
  01/01/2018 Authors: Mertz D; Li S; Luker K; Luker G; Sun D; Takayama S
• Cryopreservation and microfluidics: a focus on the oocyte.
  Reprod Fertil Dev Volume: 31 Page(s): 93 - 104
  01/01/2018 Authors: Smith GD; Takayama S
• Integration of Sensors in Gastrointestinal Organoid CultureforBiological Analysis.
  Cell Mol Gastroenterol Hepatol Volume: 6 Page(s): 123 - 131.e1
  01/01/2018 Authors: Kim G-A; Ginga NJ; Takayama S
• Bioengineering for intestinal organoid cultures.
  Curr Opin Biotechnol Volume: 47 Page(s): 51 - 58
  10/01/2017 Authors: Kim G-A; Spence JR; Takayama S
• Dispersible oxygen microsensors map oxygen gradients in three-dimensional cell cultures.
  Biomater Sci Volume: 5 Page(s): 2106 - 2113
  09/26/2017 Authors: Lesher-Prez SC; Kim G-A; Kuo C-H; Leung BM; Mong S; Kojima T; Moraes C; Thouless MD; Luker GD; Takayama S
• Laminar flow-based fabrication of thin film battery separators from aramid nanofibers
  Volume: 253
  04/02/2017 Authors: Emre A; Weerappuli P; Takayama S; Kotov N
• Application of microfluidic technologies to human assisted reproduction.
  Mol Hum Reprod Volume: 23 Page(s): 257 - 268
  04/01/2017 Authors: Smith GD; Takayama S
• New insights into mammalian signaling pathways using microfluidic pulsatile inputs and mathematical modeling.
  Integr Biol (Camb) Volume: 9 Page(s): 6 - 21
  01/23/2017 Authors: Sumit M; Takayama S; Linderman JJ
• Designing 3-D Adipospheres for Quantitative Metabolic Study.
  Volume: 1566 Page(s): 177 - 183
  01/01/2017 Authors: Akama T; Leung BM; Labuz J; Takayama S; Chun T-H
• Concomitant differentiation of a population of mouse embryonic stem cells into neuron-like cells and schwann cell-like cells in a slow-flow microfluidic device.
  Dev Dyn Volume: 246 Page(s): 7 - 27
  01/01/2017 Authors: Ramamurthy P; White JB; Yull Park J; Hume RI; Ebisu F; Mendez F; Takayama S; Barald KF
• Aqueous Two-Phase System Rehydration of Antibody-Polymer Microarrays Enables Convenient Compartmentalized Multiplex Immunoassays.
  Anal Chem Volume: 88 Page(s): 11328 - 11334
  12/06/2016 Authors: Eiden L; Yamanishi C; Takayama S; Dishinger JF
• Dynamic simulations show repeated narrowing maximizes DNA linearization in elastomeric nanochannels.
  Biomicrofluidics Volume: 10 Page(s): 064108
  11/01/2016 Authors: Han M; Kim BC; Matsuoka T; Thouless MD; Takayama S
• Pharmacokinetic profile that reduces nephrotoxicity of gentamicin in a perfused kidney-on-a-chip.
  Biofabrication Volume: 8 Page(s): 015021
  03/24/2016 Authors: Kim S; LesherPerez SC; Kim BCC; Yamanishi C; Labuz JM; Leung B; Takayama S
• Organization of Endothelial Cells, Pericytes, and Astrocytes into a 3D Microfluidic in Vitro Model of the Blood-Brain Barrier.
  Mol Pharm Volume: 13 Page(s): 895 - 906
  03/07/2016 Authors: Wang JD; Khafagy E-S; Khanafer K; Takayama S; ElSayed MEH
• Band-pass processing in a GPCR signaling pathway selects for NFAT transcription factor activation.
  Integr Biol (Camb) Volume: 7 Page(s): 1378 - 1386
  11/01/2015 Authors: Sumit M; Neubig RR; Takayama S; Linderman JJ
• An electrochemical-sensor system for real-time flow measurements in porous materials.
  Biosens Bioelectron Volume: 70 Page(s): 115 - 121
  08/15/2015 Authors: Bathany C; Han J-R; Abi-Samra K; Takayama S; Cho Y-K
• High-yield isolation of extracellular vesicles using aqueous two-phase system.
  Sci Rep Volume: 5 Page(s): 13103
  08/14/2015 Authors: Shin H; Han C; Labuz JM; Kim J; Kim J; Cho S; Gho YS; Takayama S; Park J
• Modeling selective elimination of quiescent cancer cells from bone marrow.
  Neoplasia Volume: 17 Page(s): 625 - 633
  08/01/2015 Authors: Cavnar SP; Rickelmann AD; Meguiar KF; Xiao A; Dosch J; Leung BM; Cai Lesher-Perez S; Chitta S; Luker KE; Takayama S
• Formation and manipulation of cell spheroids using a density adjusted PEG/DEX aqueous two phase system.
  Sci Rep Volume: 5 Page(s): 11891
  07/06/2015 Authors: Han C; Takayama S; Park J
• A microfluidic model to study fluid dynamics of mucus plug rupture in small lung airways.
  Biomicrofluidics Volume: 9 Page(s): 044119
  07/01/2015 Authors: Hu Y; Bian S; Grotberg J; Filoche M; White J; Takayama S; Grotberg JB
• Formation of stable small cell number three-dimensional ovarian cancer spheroids using hanging drop arrays for preclinical drug sensitivity assays.
  Gynecol Oncol Volume: 138 Page(s): 181 - 189
  07/01/2015 Authors: Raghavan S; Ward MR; Rowley KR; Wold RM; Takayama S; Buckanovich RJ; Mehta G
• Recent microfluidic devices for studying gamete and embryo biomechanics.
  J Biomech Volume: 48 Page(s): 1671 - 1678
  06/25/2015 Authors: Lai D; Takayama S; Smith GD
• Multiple independent autonomous hydraulic oscillators driven by a common gravity head.
  Nat Commun Volume: 6 Page(s): 7301
  06/15/2015 Authors: Kim S-J; Yokokawa R; Lesher-Perez SC; Takayama S
• Microscale 3D collagen cell culture assays in conventional flat-bottom 384-well plates.
  J Lab Autom Volume: 20 Page(s): 138 - 145
  04/01/2015 Authors: Leung BM; Moraes C; Cavnar SP; Luker KE; Luker GD; Takayama S
• Fracture fabrication of a multi-scale channel device that efficiently captures and linearizes DNA from dilute solutions.
  Lab Chip Volume: 15 Page(s): 1329 - 1334
  03/07/2015 Authors: Kim BC; Weerappuli P; Thouless MD; Takayama S
• Surface-templated hydrogel patterns prompt matrix-dependent migration of breast cancer cells towards chemokine-secreting cells.
  Acta Biomater Volume: 13 Page(s): 68 - 77
  02/01/2015 Authors: Kojima T; Moraes C; Cavnar SP; Luker GD; Takayama S
• Media additives to promote spheroid circularity and compactness in hanging drop platform.
  Biomater Sci Volume: 3 Page(s): 336 - 344
  02/01/2015 Authors: Leung BM; Lesher-Perez SC; Matsuoka T; Moraes C; Takayama S
• Elongation of fibers from highly viscous dextran solutions enables fabrication of rapidly dissolving drug carrying fabrics.
  Adv Healthc Mater Volume: 4 Page(s): 313 - 319
  01/28/2015 Authors: Frampton JP; Lai D; Lounds M; Chung K; Kim J; Mansfield JF; Takayama S
• Recent developments in multiplexing techniques for immunohistochemistry.
  Expert Rev Mol Diagn Volume: 15 Page(s): 1171 - 1186
  01/01/2015 Authors: Dixon AR; Bathany C; Tsuei M; White J; Barald KF; Takayama S
• A cost-effective fluorescence mini-microscope for biomedical applications.
  Lab Chip Volume: 15 Page(s): 3661 - 3669
  01/01/2015 Authors: Zhang YS; Ribas J; Nadhman A; Aleman J; Selimovi ; Lesher-Perez SC; Wang T; Manoharan V; Shin S-R; Damilano A
• Supersoft lithography: candy-based fabrication of soft silicone microstructures.
  Lab Chip Volume: 15 Page(s): 3760 - 3765
  01/01/2015 Authors: Moraes C; Labuz JM; Shao Y; Fu J; Takayama S
• Systems for multiplexing homogeneous immunoassays.
  Bioanalysis Volume: 7 Page(s): 1545 - 1556
  01/01/2015 Authors: Yamanishi CD; Chiu JH-C; Takayama S
• Cell, isoform, and environment factors shape gradients and modulate chemotaxis.
  PLoS One Volume: 10 Page(s): e0123450
  01/01/2015 Authors: Chang SL; Cavnar SP; Takayama S; Luker GD; Linderman JJ
• Slow and steady cell shrinkage reduces osmotic stress in bovine and murine oocyte and zygote vitrification.
  Hum Reprod Volume: 30 Page(s): 37 - 45
  01/01/2015 Authors: Lai D; Ding J; Smith GW; Smith GD; Takayama S
• Aqueous two-phase system-mediated antibody micropatterning enables multiplexed immunostaining of cell monolayers and tissues.
  Biotechnol J Volume: 10 Page(s): 121 - 125
  01/01/2015 Authors: Frampton JP; Tsuei M; White JB; Abraham AT; Takayama S
• Fracture-based fabrication of normally closed, adjustable, and fully reversible microscale fluidic channels.
  Small Volume: 10 Page(s): 4020 - 4029
  10/15/2014 Authors: Kim BC; Moraes C; Huang J; Matsuoka T; Thouless MD; Takayama S
• Elevating sampling.
  Lab Chip Volume: 14 Page(s): 3165 - 3171
  09/07/2014 Authors: Labuz JM; Takayama S
• Defined topologically-complex protein matrices to manipulate cell shape via three-dimensional fiber-like patterns.
  Lab Chip Volume: 14 Page(s): 2191 - 2201
  07/07/2014 Authors: Moraes C; Kim BC; Zhu X; Mills KL; Dixon AR; Thouless MD; Takayama S
• Aqueous two-phase system patterning of detection antibody solutions for cross-reaction-free multiplex ELISA.
  Sci Rep Volume: 4 Page(s): 4878
  05/02/2014 Authors: Frampton JP; White JB; Simon AB; Tsuei M; Paczesny S; Takayama S
• Microfluidic source-sink model reveals effects of biophysically distinct CXCL12 isoforms in breast cancer chemotaxis.
  Integr Biol (Camb) Volume: 6 Page(s): 564 - 576
  05/01/2014 Authors: Cavnar SP; Ray P; Moudgil P; Chang SL; Luker KE; Linderman JJ; Takayama S; Luker GD
• One-dimensional patterning of cells in silicone wells via compression-induced fracture.
  J Biomed Mater Res A Volume: 102 Page(s): 1361 - 1369
  05/01/2014 Authors: Dixon AR; Moraes C; Csete ME; Thouless MD; Philbert MA; Takayama S
• Label-free direct visual analysis of hydrolytic enzyme activity using aqueous two-phase system droplet phase transitions.
  Anal Chem Volume: 86 Page(s): 4052 - 4057
  04/15/2014 Authors: Lai D; Frampton JP; Tsuei M; Kao A; Takayama S
• Transfer, imaging, and analysis plate for facile handling of 384 hanging drop 3D tissue spheroids.
  J Lab Autom Volume: 19 Page(s): 208 - 214
  04/01/2014 Authors: Cavnar SP; Salomonsson E; Luker KE; Luker GD; Takayama S
• Pumps for microfluidic cell culture.
  Electrophoresis Volume: 35 Page(s): 245 - 257
  02/01/2014 Authors: Byun CK; Abi-Samra K; Cho Y-K; Takayama S
• Control of soft machines using actuators operated by a Braille display.
  Lab Chip Volume: 14 Page(s): 189 - 199
  01/07/2014 Authors: Mosadegh B; Mazzeo AD; Shepherd RF; Morin SA; Gupta U; Sani IZ; Lai D; Takayama S; Whitesides GM
• Aqueous two-phase system technology for patterning bacterial communities and biofilms.
  Methods Mol Biol Volume: 1147 Page(s): 23 - 32
  01/01/2014 Authors: Dwidar M; Takayama S; Mitchell RJ
• Localized micro-scale disruption of cells using laser-generated focused ultrasound.
  J Biophotonics Volume: 6 Page(s): 905 - 910
  12/01/2013 Authors: Baac HW; Frampton J; Ok JG; Takayama S; Guo LJ
• Aqueous two-phase printing of cell-containing contractile collagen microgels.
  Biomaterials Volume: 34 Page(s): 9623 - 9631
  12/01/2013 Authors: Moraes C; Simon AB; Putnam AJ; Takayama S
• Delivery of proteases in aqueous two-phase systems enables direct purification of stem cell colonies from feeder cell co-cultures for differentiation into functional cardiomyocytes.
  Adv Healthc Mater Volume: 2 Page(s): 1440 - 1444
  11/01/2013 Authors: Frampton JP; Shi H; Kao A; Parent JM; Takayama S
• External mechanical cues trigger the establishment of the anterior-posterior axis in early mouse embryos.
  Dev Cell Volume: 27 Page(s): 131 - 144
  10/28/2013 Authors: Hiramatsu R; Matsuoka T; Kimura-Yoshida C; Han S-W; Mochida K; Adachi T; Takayama S; Matsuo I
• On being the right size: scaling effects in designing a human-on-a-chip.
  Integr Biol (Camb) Volume: 5 Page(s): 1149 - 1161
  09/01/2013 Authors: Moraes C; Labuz JM; Leung BM; Inoue M; Chun T-H; Takayama S
• Microfluidic interrogation and mathematical modeling of multi-regime calcium signaling dynamics.
  Integr Biol (Camb) Volume: 5 Page(s): 932 - 939
  07/24/2013 Authors: Jovic A; Wade SM; Neubig RR; Linderman JJ; Takayama S
• Preprogrammed, parallel on-chip immunoassay using system-level capillarity control.
  Anal Chem Volume: 85 Page(s): 6902 - 6907
  07/16/2013 Authors: Kim S-J; Paczesny S; Takayama S; Kurabayashi K
• Microscale determination of aqueous two phase system binodals by droplet dehydration in oil.
  Anal Chem Volume: 85 Page(s): 5213 - 5218
  05/21/2013 Authors: Kojima T; Takayama S
• Patchy surfaces stabilize dextran-polyethylene glycol aqueous two-phase system liquid patterns.
  Langmuir Volume: 29 Page(s): 5508 - 5514
  05/07/2013 Authors: Kojima T; Takayama S
• Room temperature phosphorescence of metal-free organic materials in amorphous polymer matrices.
  J Am Chem Soc Volume: 135 Page(s): 6325 - 6329
  04/24/2013 Authors: Lee D; Bolton O; Kim BC; Youk JH; Takayama S; Kim J
• Microfluidic oscillators with widely tunable periods.
  Lab Chip Volume: 13 Page(s): 1644 - 1648
  04/21/2013 Authors: Kim S-J; Yokokawa R; Takayama S
• Cell co-culture patterning using aqueous two-phase systems.
  J Vis Exp
  03/26/2013 Authors: Frampton JP; White JB; Abraham AT; Takayama S
• Productive chemical interaction between a bacterial microcolony couple is enhanced by periodic relocation.
  J Am Chem Soc Volume: 135 Page(s): 2242 - 2247
  02/13/2013 Authors: Byun CK; Hwang H; Choi WS; Yaguchi T; Park J; Kim D; Mitchell RJ; Kim T; Cho Y-K; Takayama S
• Microfluidic systems: a new toolbox for pluripotent stem cells.
  Biotechnol J Volume: 8 Page(s): 180 - 191
  02/01/2013 Authors: Lesher-Perez SC; Frampton JP; Takayama S
• Patterning bacterial communities on epithelial cells.
  PLoS One Volume: 8 Page(s): e67165
  01/01/2013 Authors: Dwidar M; Leung BM; Yaguchi T; Takayama S; Mitchell RJ
• Nanoscale squeezing in elastomeric nanochannels for single chromatin linearization.
  Nano Lett Volume: 12 Page(s): 6480 - 6484
  12/12/2012 Authors: Matsuoka T; Kim BC; Huang J; Douville NJ; Thouless MD; Takayama S
• Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy.
  J Control Release Volume: 164 Page(s): 192 - 204
  12/10/2012 Authors: Mehta G; Hsiao AY; Ingram M; Luker GD; Takayama S
• Microfluidic automation using elastomeric valves and droplets: reducing reliance on external controllers.
  Small Volume: 8 Page(s): 2925 - 2934
  10/08/2012 Authors: Kim S-J; Lai D; Park JY; Yokokawa R; Takayama S
• Aqueous two-phase system-derived biofilms for bacterial interaction studies.
  Biomacromolecules Volume: 13 Page(s): 2655 - 2661
  09/10/2012 Authors: Yaguchi T; Dwidar M; Byun CK; Leung B; Lee S; Cho Y-K; Mitchell RJ; Takayama S
• Quantitative analysis of molecular absorption into PDMS microfluidic channels.
  Ann Biomed Eng Volume: 40 Page(s): 1862 - 1873
  09/01/2012 Authors: Wang JD; Douville NJ; Takayama S; ElSayed M
• Rapid generation of multiplexed cell cocultures using acoustic droplet ejection followed by aqueous two-phase exclusion patterning.
  Tissue Eng Part C Methods Volume: 18 Page(s): 647 - 657
  09/01/2012 Authors: Fang Y; Frampton JP; Raghavan S; Sabahi-Kaviani R; Luker G; Deng CX; Takayama S
• Lab-on-a-chip biophotonics: its application to assisted reproductive technologies.
  J Biophotonics Volume: 5 Page(s): 650 - 660
  08/01/2012 Authors: Lai D; Smith GD; Takayama S
• Real time culture and analysis of embryo metabolism using a microfluidic device with deformation based actuation.
  Lab Chip Volume: 12 Page(s): 2240 - 2246
  06/21/2012 Authors: Heo YS; Cabrera LM; Bormann CL; Smith GD; Takayama S
• Organs-on-a-chip: a focus on compartmentalized microdevices.
  Ann Biomed Eng Volume: 40 Page(s): 1211 - 1227
  06/01/2012 Authors: Moraes C; Mehta G; Lesher-Perez SC; Takayama S
• 384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids.
  Biotechnol Bioeng Volume: 109 Page(s): 1293 - 1304
  05/01/2012 Authors: Hsiao AY; Tung Y-C; Qu X; Patel LR; Pienta KJ; Takayama S
• Micro-ring structures stabilize microdroplets to enable long term spheroid culture in 384 hanging drop array plates.
  Biomed Microdevices Volume: 14 Page(s): 313 - 323
  04/01/2012 Authors: Hsiao AY; Tung Y-C; Kuo C-H; Mosadegh B; Bedenis R; Pienta KJ; Takayama S
• Secreted CXCL12 (SDF-1) forms dimers under physiological conditions.
  Biochem J Volume: 442 Page(s): 433 - 442
  03/01/2012 Authors: Ray P; Lewin SA; Mihalko LA; Lesher-Perez S-C; Takayama S; Luker KE; Luker GD
• Rethinking in vitro embryo culture: new developments in culture platforms and potential to improve assisted reproductive technologies.
  Biol Reprod Volume: 86 Page(s): 62
  03/01/2012 Authors: Smith GD; Takayama S; Swain JE
• Constant flow-driven microfluidic oscillator for different duty cycles.
  Anal Chem Volume: 84 Page(s): 1152 - 1156
  01/17/2012 Authors: Kim S-J; Yokokawa R; Lesher-Perez SC; Takayama S
• Precisely targeted delivery of cells and biomolecules within microchannels using aqueous two-phase systems.
  Biomed Microdevices Volume: 13 Page(s): 1043 - 1051
  12/01/2011 Authors: Frampton JP; Lai D; Sriram H; Takayama S
• Rounded multi-level microchannels with orifices made in one exposure enable aqueous two-phase system droplet microfluidics.
  Lab Chip Volume: 11 Page(s): 3551 - 3554
  10/21/2011 Authors: Lai D; Frampton JP; Sriram H; Takayama S
• Receptor differential activation and cooperativity better explain cellular preference for different chemoattractant gradient shapes in an EGFR system.
  Integr Biol (Camb) Volume: 3 Page(s): 1003 - 1010
  10/01/2011 Authors: White JB; Takayama S
• Microprinted feeder cells guide embryonic stem cell fate.
  Biotechnol Bioeng Volume: 108 Page(s): 2509 - 2516
  10/01/2011 Authors: Tavana H; Mosadegh B; Zamankhan P; Grotberg JB; Takayama S
• Epithelium damage and protection during reopening of occluded airways in a physiologic microfluidic pulmonary airway model.
  Biomed Microdevices Volume: 13 Page(s): 731 - 742
  08/01/2011 Authors: Tavana H; Zamankhan P; Christensen PJ; Grotberg JB; Takayama S
• Hi-Fi transmission of periodic signals amid cell-to-cell variability.
  Mol Biosyst Volume: 7 Page(s): 2238 - 2244
  07/01/2011 Authors: Jovic A; Wade SM; Miyawaki A; Neubig RR; Linderman JJ; Takayama S
• Flexible fabrication and applications of polymer nanochannels and nanoslits.
  Chem Soc Rev Volume: 40 Page(s): 3677 - 3702
  07/01/2011 Authors: Chantiwas R; Park S; Soper SA; Kim BC; Takayama S; Sunkara V; Hwang H; Cho Y-K
• Aqueous biphasic microprinting approach to tissue engineering.
  Biomicrofluidics Volume: 5 Page(s): 13404
  03/30/2011 Authors: Tavana H; Takayama S
• High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array.
  Analyst Volume: 136 Page(s): 473 - 478
  02/07/2011 Authors: Tung Y-C; Hsiao AY; Allen SG; Torisawa Y-S; Ho M; Takayama S
• Microbioreactors
  Page(s): 289 - 301
  01/01/2011 Authors: Znidarsic-Plazl P; Plazl I
• Artificial hematopoietic stem cell niche: bioscaffolds to microfluidics to mathematical simulations.
  Curr Top Med Chem Volume: 11 Page(s): 1599 - 1605
  01/01/2011 Authors: Didwania M; Didwania A; Mehta G; Basak GW; Yasukawa S; Takayama S; de Necochea-Campion R; Srivastava A; Carrier E
• Transwells with microstamped membranes produce micropatterned two-dimensional and three-dimensional co-cultures.
  Tissue Eng Part C Methods Volume: 17 Page(s): 61 - 67
  01/01/2011 Authors: Torisawa Y-S; Mosadegh B; Cavnar SP; Ho M; Takayama S
• Phase-locked signals elucidate circuit architecture of an oscillatory pathway.
  PLoS Comput Biol Volume: 6 Page(s): e1001040
  12/23/2010 Authors: Jovic A; Howell B; Cote M; Wade SM; Mehta K; Miyawaki A; Neubig RR; Linderman JJ; Takayama S
• Multiplexed spectral signature detection for microfluidic color-coded bioparticle flow.
  Anal Chem Volume: 82 Page(s): 9506 - 9512
  11/15/2010 Authors: Huang N-T; Truxal SC; Tung Y-C; Hsiao AY; Luker GD; Takayama S; Kurabayashi K
• Uniform cell seeding and generation of overlapping gradient profiles in a multiplexed microchamber device with normally-closed valves.
  Lab Chip Volume: 10 Page(s): 2959 - 2964
  11/07/2010 Authors: Mosadegh B; Agarwal M; Tavana H; Bersano-Begey T; Torisawa Y-S; Morell M; Wyatt MJ; O'Shea KS; Barald KF; Takayama S
• Micropatterning bacterial suspensions using aqueous two phase systems.
  Analyst Volume: 135 Page(s): 2848 - 2852
  11/01/2010 Authors: Yaguchi T; Lee S; Choi WS; Kim D; Kim T; Mitchell RJ; Takayama S
• Microfluidic platform for chemotaxis in gradients formed by CXCL12 source-sink cells.
  Integr Biol (Camb) Volume: 2 Page(s): 680 - 686
  11/01/2010 Authors: Torisawa Y-S; Mosadegh B; Bersano-Begey T; Steele JM; Luker KE; Luker GD; Takayama S
• Guided corona generates wettability patterns that selectively direct cell attachment inside closed microchannels.
  Biomed Microdevices Volume: 12 Page(s): 769 - 775
  10/01/2010 Authors: Dixon A; Takayama S
• Bioengineered three-dimensional physiological model of colonic longitudinal smooth muscle in vitro.
  Tissue Eng Part C Methods Volume: 16 Page(s): 999 - 1009
  10/01/2010 Authors: Raghavan S; Lam MT; Foster LL; Gilmont RR; Somara S; Takayama S; Bitar KN
• Simultaneous fabrication of PDMS through-holes for three-dimensional microfluidic applications.
  Lab Chip Volume: 10 Page(s): 1983 - 1986
  08/07/2010 Authors: Mosadegh B; Agarwal M; Torisawa Y-S; Takayama S
• The art of reporter proteins in science: past, present and future applications.
  BMB Rep Volume: 43 Page(s): 451 - 460
  07/01/2010 Authors: Ghim C-M; Lee SK; Takayama S; Mitchell RJ
• Polymeric aqueous biphasic systems for non-contact cell printing on cells: engineering heterocellular embryonic stem cell niches.
  Adv Mater Volume: 22 Page(s): 2628 - 2631
  06/25/2010 Authors: Tavana H; Mosadegh B; Takayama S
• Regulating microenvironmental stimuli for stem cells and cancer cells using microsystems.
  Integr Biol (Camb) Volume: 2 Page(s): 229 - 240
  06/01/2010 Authors: Park JY; Takayama S; Lee S-H
• Patterned electrode-based amperometric gas sensor for direct nitric oxide detection within microfluidic devices.
  Anal Chem Volume: 82 Page(s): 3300 - 3305
  04/15/2010 Authors: Cha W; Tung Y-C; Meyerhoff ME; Takayama S
• Fabrication of two-layered channel system with embedded electrodes to measure resistance across epithelial and endothelial barriers.
  Anal Chem Volume: 82 Page(s): 2505 - 2511
  03/15/2010 Authors: Douville NJ; Tung Y-C; Li R; Wang JD; El-Sayed MEH; Takayama S
• Dynamics of liquid plugs of buffer and surfactant solutions in a micro-engineered pulmonary airway model.
  Langmuir Volume: 26 Page(s): 3744 - 3752
  03/02/2010 Authors: Tavana H; Kuo C-H; Lee QY; Mosadegh B; Huh D; Christensen PJ; Grotberg JB; Takayama S
• Microfluidic Engineering of Stem Cell Niches and 3D Tissue Models
  Volume: 46 Page(s): S77 - S77
  03/01/2010 Authors: Takayama S
• Patterning alginate hydrogels using light-directed release of caged calcium in a microfluidic device.
  Biomed Microdevices Volume: 12 Page(s): 145 - 151
  02/01/2010 Authors: Chueh B-H; Zheng Y; Torisawa Y-S; Hsiao AY; Ge C; Hsiong S; Huebsch N; Franceschi R; Mooney DJ; Takayama S
• Microfluidic hydrodynamic cellular patterning for systematic formation of co-culture spheroids.
  Integr Biol (Camb) Volume: 1 Page(s): 649 - 654
  12/01/2009 Authors: Torisawa Y-S; Mosadegh B; Luker GD; Morell M; O'Shea KS; Takayama S
• Nanolitre liquid patterning in aqueous environments for spatially defined reagent delivery to mammalian cells.
  Nat Mater Volume: 8 Page(s): 736 - 741
  09/01/2009 Authors: Tavana H; Jovic A; Mosadegh B; Lee QY; Liu X; Luker KE; Luker GD; Weiss SJ; Takayama S
• Quantitative inference of cellular parameters from microfluidic cell culture systems.
  Biotechnol Bioeng Volume: 103 Page(s): 966 - 974
  08/01/2009 Authors: Mehta K; Mehta G; Takayama S; Linderman J
• Microfluidic culture of single human embryonic stem cell colonies.
  Lab Chip Volume: 9 Page(s): 1749 - 1755
  06/21/2009 Authors: Villa-Diaz LG; Torisawa Y-S; Uchida T; Ding J; Nogueira-de-Souza NC; O'Shea KS; Takayama S; Smith GD
• Microfluidic endothelium for studying the intravascular adhesion of metastatic breast cancer cells.
  PLoS One Volume: 4 Page(s): e5756
  06/01/2009 Authors: Song JW; Cavnar SP; Walker AC; Luker KE; Gupta M; Tung Y-C; Luker GD; Takayama S
• Microfluidic system for formation of PC-3 prostate cancer co-culture spheroids.
  Biomaterials Volume: 30 Page(s): 3020 - 3027
  06/01/2009 Authors: Hsiao AY; Torisawa Y-S; Tung Y-C; Sud S; Taichman RS; Pienta KJ; Takayama S
• A student team in a University of Michigan biomedical engineering design course constructs a microfluidic bioreactor for studies of zebrafish development.
  Zebrafish Volume: 6 Page(s): 201 - 213
  06/01/2009 Authors: Shen Y-C; Li D; Al-Shoaibi A; Bersano-Begey T; Chen H; Ali S; Flak B; Perrin C; Winslow M; Shah H
• Hard top soft bottom microfluidic devices for cell culture and chemical analysis.
  Anal Chem Volume: 81 Page(s): 3714 - 3722
  05/15/2009 Authors: Mehta G; Lee J; Cha W; Tung Y-C; Linderman JJ; Takayama S
• Development of a Three-Dimensional Physiological Model of Colonic Longitudinal Smooth Muscle In Vitro Lined Up in Longitudinal Axis
  Volume: 136 Page(s): A220 - A220
  05/01/2009 Authors: Raghavan S; Lam M; Foster LL; Gilmont RR; Somara S; Takayama S; Bitar KN
• Teaching old liquids new tricks: Aqueous two-phase systems for cell and reagent micropatterning
  Volume: 237 Page(s): 336 - 336
  03/22/2009 Authors: Takayama S; Tavana H; Jovik A; Mosadegh B
• External compression-induced fracture patterning on the surface of poly(dimethylsiloxane) cubes and microspheres.
  Langmuir Volume: 25 Page(s): 3102 - 3107
  03/03/2009 Authors: Uchida T; Mills KL; Kuo C-H; Roh W; Tung Y-C; Garner AL; Koide K; Thouless MD; Takayama S
• Microfeature guided skeletal muscle tissue engineering for highly organized 3-dimensional free-standing constructs.
  Biomaterials Volume: 30 Page(s): 1150 - 1155
  02/01/2009 Authors: Lam MT; Huang Y-C; Birla RK; Takayama S
• Microfluidics cell culture with sensing and SqueezeFluidics.
  Volume: 2009 Page(s): 6374 - 6375
  01/01/2009 Authors: Takayama S
• Liquid and surfactant delivery into pulmonary airways.
  Respir Physiol Neurobiol Volume: 163 Page(s): 222 - 231
  11/30/2008 Authors: Halpern D; Fujioka H; Takayama S; Grotberg JB
• DNA linearization through confinement in nanofluidic channels.
  Anal Bioanal Chem Volume: 391 Page(s): 2395 - 2409
  08/01/2008 Authors: Douville N; Huh D; Takayama S
• Electromechanical properties of pressure-actuated poly(dimethylsiloxane) microfluidic push-down valves.
  Anal Chem Volume: 80 Page(s): 6110 - 6113
  08/01/2008 Authors: Chen H; Gu W; Cellar N; Kennedy R; Takayama S; Meiners J-C
• Unsteady propagation of a liquid plug in a liquid-lined straight tube.
  Phys Fluids (1994) Volume: 20 Page(s): 62104
  06/01/2008 Authors: Fujioka H; Takayama S; Grotberg JB
• Individually programmable cell stretching microwell arrays actuated by a Braille display.
  Biomaterials Volume: 29 Page(s): 2646 - 2655
  06/01/2008 Authors: Kamotani Y; Bersano-Begey T; Kato N; Tung Y-C; Huh D; Song JW; Takayama S
• Reversible on-demand cell alignment using reconfigurable microtopography.
  Biomaterials Volume: 29 Page(s): 1705 - 1712
  04/01/2008 Authors: Lam MT; Clem WC; Takayama S
• Acoustically detectable cellular-level lung injury induced by fluid mechanical stresses in microfluidic airway systems.
  Proc Natl Acad Sci U S A Volume: 104 Page(s): 18886 - 18891
  11/27/2007 Authors: Huh D; Fujioka H; Tung Y-C; Futai N; Paine R; Grotberg JB; Takayama S
• Assessment of sperm chemokinesis with exposure to jelly coats of sea urchin eggs and resact: a microfluidic experiment and numerical study.
  J Exp Biol Volume: 210 Page(s): 3805 - 3820
  11/01/2007 Authors: Inamdar MV; Kim T; Chung Y-K; Was AM; Xiang X; Wang C-W; Takayama S; Lastoskie CM; Thomas FIM; Sastry AM
• Small volume low mechanical stress cytometry using computer-controlled Braille display microfluidics.
  Lab Chip Volume: 7 Page(s): 1497 - 1503
  11/01/2007 Authors: Tung Y-C; Torisawa Y-S; Futai N; Takayama S
• Gamete and embryo isolation and culture with microfluidics.
  Theriogenology Volume: 68 Suppl 1 Page(s): S190 - S195
  09/01/2007 Authors: Smith GD; Takayama S
• Preparation of porous materials by high temperature water treatment of PVC
  Volume: 234
  08/19/2007 Authors: Takayama S; Kimata M; Tagaya H
• Tuneable elastomeric nanochannels for nanofluidic manipulation.
  Nat Mater Volume: 6 Page(s): 424 - 428
  06/01/2007 Authors: Huh D; Mills KL; Zhu X; Burns MA; Thouless MD; Takayama S
• Efficient formation of uniform-sized embryoid bodies using a compartmentalized microchannel device.
  Lab Chip Volume: 7 Page(s): 770 - 776
  06/01/2007 Authors: Torisawa Y-S; Chueh B-H; Huh D; Ramamurthy P; Roth TM; Barald KF; Takayama S
• Leakage-free bonding of porous membranes into layered microfluidic array systems.
  Anal Chem Volume: 79 Page(s): 3504 - 3508
  05/01/2007 Authors: Chueh B-H; Huh D; Kyrtsos CR; Houssin T; Futai N; Takayama S
• Quantitative measurement and control of oxygen levels in microfluidic poly(dimethylsiloxane) bioreactors during cell culture.
  Biomed Microdevices Volume: 9 Page(s): 123 - 134
  04/01/2007 Authors: Mehta G; Mehta K; Sud D; Song JW; Bersano-Begey T; Futai N; Heo YS; Mycek M-A; Linderman JJ; Takayama S
• Gravity-driven microfluidic particle sorting device with hydrodynamic separation amplification.
  Anal Chem Volume: 79 Page(s): 1369 - 1376
  02/15/2007 Authors: Huh D; Bahng JH; Ling Y; Wei H-H; Kripfgans OD; Fowlkes JB; Grotberg JB; Takayama S
• Characterization and resolution of evaporation-mediated osmolality shifts that constrain microfluidic cell culture in poly(dimethylsiloxane) devices.
  Anal Chem Volume: 79 Page(s): 1126 - 1134
  02/01/2007 Authors: Heo YS; Cabrera LM; Song JW; Futai N; Tung Y-C; Smith GD; Takayama S
• The effect of continuous wavy micropatterns on silicone substrates on the alignment of skeletal muscle myoblasts and myotubes.
  Biomaterials Volume: 27 Page(s): 4340 - 4347
  08/01/2006 Authors: Lam MT; Sim S; Zhu X; Takayama S
• A surface-modified sperm sorting device with long-term stability.
  Biomed Microdevices Volume: 8 Page(s): 99 - 107
  06/01/2006 Authors: Wu JM; Chung Y; Belford KJ; Smith GD; Takayama S; Lahann J
• IVF within microfluidic channels requires lower total numbers and lower concentrations of sperm.
  Hum Reprod Volume: 21 Page(s): 477 - 483
  02/01/2006 Authors: Suh RS; Zhu X; Phadke N; Ohl DA; Takayama S; Smith GD
• Optical imaging in microfluidic bioreactors enables oxygen monitoring for continuous cell culture.
  J Biomed Opt Volume: 11 Page(s): 050504
  01/01/2006 Authors: Sud D; Mehta G; Mehta K; Linderman J; Takayama S; Mycek M-A
• Handheld recirculation system and customized media for microfluidic cell culture.
  Lab Chip Volume: 6 Page(s): 149 - 154
  01/01/2006 Authors: Futai N; Gu W; Song JW; Takayama S
• Microscale integrated sperm sorter.
  Methods Mol Biol Volume: 321 Page(s): 227 - 244
  01/01/2006 Authors: Chung Y; Zhu X; Gu W; Smith GD; Takayama S
• Computer-controlled microcirculatory support system for endothelial cell culture and shearing.
  Anal Chem Volume: 77 Page(s): 3993 - 3999
  07/01/2005 Authors: Song JW; Gu W; Futai N; Warner KA; Nor JE; Takayama S
• Microfluidics for flow cytometric analysis of cells and particles.
  Physiol Meas Volume: 26 Page(s): R73 - R98
  06/01/2005 Authors: Huh D; Gu W; Kamotani Y; Grotberg JB; Takayama S
• Fabrication of reconfigurable protein matrices by cracking.
  Nat Mater Volume: 4 Page(s): 403 - 406
  05/01/2005 Authors: Zhu X; Mills KL; Peters PR; Bahng JH; Liu EH; Shim J; Naruse K; Csete ME; Thouless MD; Takayama S
• Microfluidic applications for andrology.
  J Androl Volume: 26 Page(s): 664 - 670
  01/01/2005 Authors: Suh R; Takayama S; Smith GD
• Computerized microfluidic cell culture using elastomeric channels and Braille displays.
  Proc Natl Acad Sci U S A Volume: 101 Page(s): 15861 - 15866
  11/09/2004 Authors: Gu W; Zhu X; Futai N; Cho BS; Takayama S
• Arrays of horizontally-oriented mini-reservoirs generate steady microfluidic flows for continuous perfusion cell culture and gradient generation.
  Analyst Volume: 129 Page(s): 1026 - 1031
  11/01/2004 Authors: Zhu X; Yi Chu L; Chueh B-H; Shen M; Hazarika B; Phadke N; Takayama S
• Reversible switching of high-speed air-liquid two-phase flows using electrowetting-assisted flow-pattern change.
  J Am Chem Soc Volume: 125 Page(s): 14678 - 14679
  12/03/2003 Authors: Huh D; Tkaczyk AH; Bahng JH; Chang Y; Wei H-H; Grotberg JB; Kim C-J; Kurabayashi K; Takayama S
• Fabrication of microfluidic mixers and artificial vasculatures using a high-brightness diode-pumped Nd:YAG laser direct write method.
  Lab Chip Volume: 3 Page(s): 318 - 323
  11/01/2003 Authors: Lim D; Kamotani Y; Cho B; Mazumder J; Takayama S
• Passively driven integrated microfluidic system for separation of motile sperm.
  Anal Chem Volume: 75 Page(s): 1671 - 1675
  04/01/2003 Authors: Cho BS; Schuster TG; Zhu X; Chang D; Smith GD; Takayama S
• Rethinking gamete/embryo isolation and culture with microfluidics.
  Hum Reprod Update Volume: 9 Page(s): 451 - 461
  01/01/2003 Authors: Suh RS; Phadke N; Ohl DA; Takayama S; Smith GD
• Isolation of motile spermatozoa from semen samples using microfluidics.
  Reprod Biomed Online Volume: 7 Page(s): 75 - 81
  01/01/2003 Authors: Schuster TG; Cho B; Keller LM; Takayama S; Smith GD
• Micro- and nanotechnologies for studying cellular function.
  Curr Top Med Chem Volume: 3 Page(s): 687 - 703
  01/01/2003 Authors: Shim J; Bersano-Begey TF; Zhu X; Tkaczyk AH; Linderman JJ; Takayama S
• Lateral propagation of EGF signaling after local stimulation is dependent on receptor density.
  Dev Cell Volume: 3 Page(s): 245 - 257
  08/01/2002 Authors: Sawano A; Takayama S; Matsuda M; Miyawaki A
• Subcellular positioning of small molecules.
  Nature Volume: 411 Page(s): 1016
  06/28/2001 Authors: Takayama S; Ostuni E; LeDuc P; Naruse K; Ingber DE; Whitesides GM
• Soft lithography in biology and biochemistry.
  Volume: 3 Page(s): 335 - 373
  01/01/2001 Authors: Whitesides GM; Ostuni E; Takayama S; Jiang X; Ingber DE
• Fabrication inside microchannels using fluid flow.
  Acc Chem Res Volume: 33 Page(s): 841 - 847
  12/01/2000 Authors: Kenis PJ; Ismagilov RF; Takayama S; Whitesides GM; Li S; White HS
• Patterning proteins and cells using soft lithography.
  Biomaterials Volume: 20 Page(s): 2363 - 2376
  12/01/1999 Authors: Kane RS; Takayama S; Ostuni E; Ingber DE; Whitesides GM
• Patterning cells and their environments using multiple laminar fluid flows in capillary networks.
  Proc Natl Acad Sci U S A Volume: 96 Page(s): 5545 - 5548
  05/11/1999 Authors: Takayama S; McDonald JC; Ostuni E; Liang MN; Kenis PJ; Ismagilov RF; Whitesides GM
• Selective inhibition of beta-1,4- and alpha-1,3-galactosyltransferases: donor sugar-nucleotide based approach.
  Bioorg Med Chem Volume: 7 Page(s): 401 - 409
  02/01/1999 Authors: Takayama S; Chung SJ; Igarashi Y; Ichikawa Y; Sepp A; Lechler RI; Wu J; Hayashi T; Siuzdak G; Wong CH
• Acceptor substrate-based selective inhibition of galactosyltransferases.
  Bioorg Med Chem Lett Volume: 8 Page(s): 3359 - 3364
  12/01/1998 Authors: Chung SJ; Takayama S; Wong CH
• Chemoenzymatic synthesis of iminocyclitol derivatives: a useful library strategy for the development of selective fucosyltransfer enzymes inhibitors.
  Bioorg Med Chem Lett Volume: 8 Page(s): 3353 - 3358
  12/01/1998 Authors: Wischnat R; Martin R; Takayama S; Wong CH
• Microbial aldolases and transketolases: new biocatalytic approaches to simple and complex sugars.
  Volume: 51 Page(s): 285 - 310
  01/01/1997 Authors: Takayama S; McGarvey GJ; Wong CH
• Mechanism and specificity of human alpha-1,3-fucosyltransferase V.
  Biochemistry Volume: 35 Page(s): 11183 - 11195
  08/27/1996 Authors: Murray BW; Takayama S; Schultz J; Wong CH
• Reduction of bicyclo[3.3.1]nonane-2,8-diones with baker's yeast.
  Bioorg Med Chem Volume: 2 Page(s): 395 - 401
  06/01/1994 Authors: Mori K; Takayama S; Kido M