Publications

• Real-world outcomes for young adult patients receiving CD19 CAR T-cell therapy.
  Blood Adv Volume: 9 Page(s): 2763 - 2772
  06/10/2025 Authors: Lust H; Schultz LM; Kwon S; Roloff GW; Aldoss I; Baggott C; John S; Rossoff JE; McNerney KO; Fabrizio VA
• Identification of leukemia-enriched signature through the development of a comprehensive pediatric single-cell atlas.
  Nat Commun Volume: 16 Page(s): 4114
  05/02/2025 Authors: Mumme HL; Huang C; Ohlstrom D; Bakhtiari M; Raikar SS; DeRyckere D; Qayed M; Castellino SM; Wechsler DS; Porter CC
• Project EVOLVE: An international analysis of postimmunotherapy lineage switch, an emergent form of relapse in leukemia.
  Blood
  04/07/2025 Authors: Silbert SK; Rankin AW; Hoang CN; Semchenkova A; Myers RM; Zerkalenkova E; Wang H-W; Kovach AE; Yuan CM; Delgado Colon D
• Engineering safe anti-CD19-CD28 CAR T cells with CD8a hinge domain in serum-free media for adoptive immunotherapy.
  Front Immunol Volume: 16 Page(s): 1545549
  01/01/2025 Authors: Muthuvel M; Ganapathy T; Spencer T; Raikar SS; Thangavel S; Srivastava A; Martin S
• MERTK inhibition selectively activates a DC - T-cell axis to provide anti-leukemia immunity.
  Leukemia Volume: 38 Page(s): 2685 - 2698
  12/01/2024 Authors: Huelse JM; Bhasin SS; Jacobsen KM; Yim J; Thomas BE; Branella GM; Bakhtiari M; Chimenti ML; Baxter TA; Raikar SS
• Real-world use of tisagenlecleucel in children and young adults with relapsed or refractory B-cell lymphomas.
  Volume: 8 Page(s): 4164 - 4168
  08/13/2024 Authors: Bender JD; Damodharan S; Capitini CM; Moskop A; Toner K; Vatsayan A; Talano J-A; Baggott C; Schiff D; Katsanis E
• Development of a microfluidic cell transfection device into gene-edited CAR T cell manufacturing workflow.
  Lab Chip Volume: 23 Page(s): 4804 - 4820
  11/07/2023 Authors: Yu T; Jhita N; Shankles P; Fedanov A; Kramer N; Raikar SS; Sulchek T
• Single-cell RNA sequencing distinctly characterizes the wide heterogeneity in pediatric mixed phenotype acute leukemia.
  Genome Med Volume: 15 Page(s): 83
  10/16/2023 Authors: Mumme HL; Raikar SS; Bhasin SS; Thomas BE; Lawrence T; Weinzierl EP; Pang Y; DeRyckere D; Gawad C; Wechsler DS
• Single-cell analysis reveals altered tumor microenvironments of relapse- and remission-associated pediatric acute myeloid leukemia.
  Nat Commun Volume: 14 Page(s): 6209
  10/05/2023 Authors: Mumme H; Thomas BE; Bhasin SS; Krishnan U; Dwivedi B; Perumalla P; Sarkar D; Ulukaya GB; Sabnis HS; Park SI
• Pediatric T-cell acute lymphoblastic leukemia blast signature and MRD associated immune environment changes defined by single cell transcriptomics analysis.
  Sci Rep Volume: 13 Page(s): 12556
  08/02/2023 Authors: Bhasin SS; Thomas BE; Summers RJ; Sarkar D; Mumme H; Pilcher W; Emam M; Raikar SS; Park SI; Castellino SM
• Enhancing the effectiveness of Tcells by mRNA transfection of chimeric antigen receptors or bispecific Tcell engagers.
  Mol Ther Oncolytics Volume: 29 Page(s): 145 - 157
  06/15/2023 Authors: Becker SA; Petrich BG; Yu B; Knight KA; Brown HC; Raikar SS; Doering CB; Spencer HT
• Multicolor Light-Induced Immune Activation via Polymer Photocaged Cytokines.
  Biomacromolecules Volume: 24 Page(s): 1164 - 1172
  03/13/2023 Authors: Birnbaum LA; Sullivan EC; Do P; Uricoli B; Raikar SS; Porter CC; Henry CJ; Dreaden EC
• Novel Microfluidic Delivery Device for CRISPR Cas9 Editing of T Cells for Adoptive Cellular Therapy
  Volume: 30 Page(s): 448 - 448
  04/01/2022 Authors: Yu T; Jhita N; Shankles PG; Raikar SS; Sulchek TA
• Obesity-induced galectin-9 is a therapeutic target in B-cell acute lymphoblastic leukemia.
  Nat Commun Volume: 13 Page(s): 1157
  03/03/2022 Authors: Lee M; Hamilton JAG; Talekar GR; Ross AJ; Michael L; Rupji M; Dwivedi B; Raikar SS; Boss J; Scharer CD
• Cryptic t(6;11) KMT2A rearrangement in a pediatric acute myeloid leukemia patient detected by next-generation sequencing and dual-fusion FISH analysis.
  Pediatr Blood Cancer Volume: 69 Page(s): e29428
  03/01/2022 Authors: Raghunandan S; Jain J; Saxe D; Pauly M; Aljudi AA; Ketterling RP; Carter AB; Raikar SS
• PI3K/ inhibition promotes human CART cell epigenetic and metabolic reprogramming to enhance antitumor cytotoxicity.
  Blood Volume: 139 Page(s): 523 - 537
  01/27/2022 Authors: Funk CR; Wang S; Chen KZ; Waller A; Sharma A; Edgar CL; Gupta VA; Chandrakasan S; Zoine JT; Fedanov A
• Allogeneic gamma delta T cells as adoptive cellular therapy for hematologic malignancies.
  Explor Immunol Volume: 2 Page(s): 334 - 350
  01/01/2022 Authors: Jhita N; Raikar SS
• Mixed phenotype acute leukemia in a child associated with a NUP98-NSD1 fusion and NRAS p.Gly61Arg mutation.
  Cancer Rep (Hoboken) Volume: 4 Page(s): e1372
  08/01/2021 Authors: Ganapathi SS; Raikar SS; Yatsenko SA; Djokic M; Bukowinski A
• CRYPTIC t(6;11) KMT2A-REARRANGEMENT IN A CHILD WITH AML DETECTED BY NEXT GENERATION SEQUENCING
  Volume: 68 Page(s): S147 - S148
  06/01/2021 Authors: Raghunandan S; Jain J; Saxe D; Pauly M; Aljudi A; Carter A; Raikar S
• OBESITY ATTENUTATES T-CELL FUNCTION WHICH IMPACTS T-CELL IMMUNOTHERAPIES IN LYMPHOBLASTIC LEUKEMIA
  Volume: 68 Page(s): S5 - S5
  06/01/2021 Authors: Ross A; Ank R; Lee M; Hamilton J; Story J; Raikar S; Do P; Porter C; Henry C
• Interleukin-37 improves T-cell-mediated immunity and chimeric antigen receptor T-cell therapy in aged backgrounds.
  Aging Cell Volume: 20 Page(s): e13309
  02/01/2021 Authors: Hamilton JAG; Lee MY; Hunter R; Ank RS; Story JY; Talekar G; Sisroe T; Ballak DB; Fedanov A; Porter CC
• Bortezomib enhances cytotoxicity of ex vivo-expanded gamma delta T cells against acute myeloid leukemia and T-cell acute lymphoblastic leukemia.
  Cytotherapy Volume: 23 Page(s): 12 - 24
  01/01/2021 Authors: Story JY; Zoine JT; Burnham RE; Hamilton JAG; Spencer HT; Doering CB; Raikar SS
• Sustained Complete Molecular Remission With Imatinib Monotherapy in a Child Presenting With Blast Phase FIP1L1-PDGFRA-Associated Myeloid Neoplasm With Eosinophilia.
  Hemasphere Volume: 4 Page(s): e486
  12/01/2020 Authors: Jain J; Weinzierl EP; Saxe D; Bergsagel J; Gotlib J; Reiter A; Raikar SS
• Obesity Attenuates T-Cell Function Which Impacts the Efficacy of T-Cell Based Immunotherapies in Acute Lymphoblastic Leukemia
  Volume: 136
  11/05/2020 Authors: Ross A; Lee M; Hamilton J; Ank R; Do P; Story J; Raikar SS; Dreaden E; Porter CC; Henry CJ
• Single Cell Transcriptomics Revealed AML and Non-AML Cell Clusters Relevant to Relapse and Remission in Pediatric AML
  Volume: 136
  11/05/2020 Authors: Thomas BE; Perumalla P; Bhasin SS; Sarkar D; Dwivedi B; Park SI; DeRyckere D; Henry CJ; Raikar SS; Porter CC
• Significance of minimal residual disease in pediatric mixed phenotype acute leukemia: a multicenter cohort study.
  Leukemia Volume: 34 Page(s): 1741 - 1750
  07/01/2020 Authors: Oberley MJ; Raikar SS; Wertheim GB; Malvar J; Sposto R; Rabin KR; Punia JN; Seif AE; Cahen VC; Schore RJ
• OBESITY IMPAIRS T-CELL FUNCTION WHICH MAY IMPACT THE EFFICACY OF CAR T-CELLS IN PEDIATRIC LEUKEMIA
  Volume: 67 Page(s): S5 - S6
  06/01/2020 Authors: Ross A; Lee M; Hamilton J; Talekar G; Henry C; Raikar S; Story J
• IMATINIB MONOTHERAPY IN A CHILD WITH BLAST PHASE FIP1L1-PDGFRA MYELOID NEOPLASM WITH EOSINOPHILIA
  Volume: 67 Page(s): S188 - S189
  06/01/2020 Authors: Jain J; Weinzierl E; Saxe D; Bergsagel D; Raikar S
• Bortezomib Significantly Enhances Gamma Delta T-Cell Mediated Lysis of AML and T-ALL
  Volume: 28 Page(s): 498 - 498
  04/28/2020 Authors: Story JY; Zoine JT; Burnham RE; Spencer HT; Doering CB; Raikar SS
• Targeting T cell malignancies using CAR-based immunotherapy: challenges and potential solutions.
  J Hematol Oncol Volume: 12 Page(s): 141
  12/29/2019 Authors: Fleischer LC; Spencer HT; Raikar SS
• Clonal Evolution of B-Cell Acute Lymphoblastic Leukemia with del(9)(p13p21) into Mixed Phenotype Acute Leukemia Presenting as an Isolated Testicular Relapse.
  Reports (MDPI) Volume: 2
  09/01/2019 Authors: Miller LH; Park SI; Saxe D; Lew G; Raikar SS
• Minimal Residual Disease Risk-Stratification in Pediatric Mixed Phenotype Acute Leukemia: Results of a Multi-Center Cohort Study
  Volume: 132
  11/29/2018 Authors: Oberley MJ; Raikar SS; Malvar J; Wertheim G; Seif AE; Guinipero T; Sposto R; Rabin KR; Punia JN; Schore RJ
• Acquired Hypofibrinogenemia Before Asparaginase Exposure During Induction Therapy for Pediatric Acute Lymphoblastic Leukemia: A Report of 2 Cases and Review of the Literature.
  J Pediatr Hematol Oncol Volume: 40 Page(s): e470 - e472
  10/01/2018 Authors: Raikar SS; Felker J; Patel KN; Lew G; Sidonio RF
• Targeting T-cell Leukemia with CD5-Based Chimeric Antigen Receptor-Modified gamma delta T Cells
  Volume: 26 Page(s): 57 - 57
  05/01/2018 Authors: Fleischer LC; Zoine JT; Ryan RE; Raikar SS; Doering CB; Spencer HT
• Hyperleukocytosis in infant acute leukemia: a role for manual exchange transfusion for leukoreduction.
  Transfusion Volume: 58 Page(s): 1149 - 1156
  05/01/2018 Authors: Runco DV; Josephson CD; Raikar SS; Goldsmith KC; Lew G; Pauly M; Fasano RM
• Hurdles Associated with the Translational Use of Genetically Modified Cells.
  Curr Stem Cell Rep Volume: 4 Page(s): 39 - 45
  03/01/2018 Authors: Raikar SS; Spencer HT
• Improving T-cell expansion and function for adoptive T-cell therapy using ex vivo treatment with PI3K inhibitors and VIP antagonists.
  Blood Adv Volume: 2 Page(s): 210 - 223
  02/13/2018 Authors: Petersen CT; Hassan M; Morris AB; Jeffery J; Lee K; Jagirdar N; Staton AD; Raikar SS; Spencer HT; Sulchek T
• Isolated myeloperoxidase expression in pediatric B/myeloid mixed phenotype acute leukemia is linked with better survival.
  Blood Volume: 131 Page(s): 573 - 577
  02/01/2018 Authors: Raikar SS; Park SI; Leong T; Jaye DL; Keller FG; Horan JT; Woods WG
• Development of chimeric antigen receptors targeting T-cell malignancies using two structurally different anti-CD5 antigen binding domains in NK and CRISPR-edited T cell lines.
  Oncoimmunology Volume: 7 Page(s): e1407898
  01/01/2018 Authors: Raikar SS; Fleischer LC; Moot R; Fedanov A; Paik NY; Knight KA; Doering CB; Spencer HT
• Engineering CD5-Targeted Chimeric Antigen Receptors and Edited T Cells for the Treatment of T-Cell Leukemia
  Volume: 130
  12/07/2017 Authors: Fleischer LC; Raikar SS; Moot R; Knight KA; Doering CB; Spencer HT
• Targeting T-Cell Malignancies with Chimeric Antigen Receptors Using Two Structurally Different Antigen Binding Domains Against CD5
  Volume: 130
  12/07/2017 Authors: Raikar SS; Fleischer LC; Moot R; Paik NY; Knight K; Doering CB; Spencer HT
• Isolated Myeloperoxidase Expression in Pediatric B/Myeloid Mixed Phenotype Acute Leukemia Is Associated with Improved Survival Using ALL-Only Regimens
  Volume: 130
  12/07/2017 Authors: Raikar SS; Park S; Leong T; Jaye DL; Keller FG; Horan JT; Woods WG
• Early T-Cell Precursor Acute Lymphoblastic Leukemia in an Infant With an NRAS Q61R Mutation and Clinical Features of Juvenile Myelomonocytic Leukemia.
  Pediatr Blood Cancer Volume: 63 Page(s): 1667 - 1670
  09/01/2016 Authors: Raikar SS; Scarborough JD; Sabnis H; Bergsagel J; Wu D; Cooper TM; Keller FG; Wood BL; Bunting ST
• DEVELOPMENT OF CHIMERIC ANTIGEN RECEPTORS FOR NATURAL KILLER CELL-BASED TREATMENT OF T-CELL MALIGNANCIES
  PEDIATRIC BLOOD & CANCER Volume: 63 Page(s): S29 - S30
  06/01/2016 Authors: Raikar S; Tylawsky D; Moot R; Fleischer L; McCarty D; Doering C; Spencer T
• Variable Lymphocyte Receptors Enable Development of Chimeric Antigen Receptors for the Treatment of T-Cell Malignancies
  Volume: 24 Page(s): S80 - S81
  05/01/2016 Authors: Raikar SS; Tylawsky D; Moot R; Fleischer L; McCarty D; Doering C; Spencer HT
• A Novel Approach to Expand Antigen Recognition in Chimeric Antigen Receptors
  Volume: 24 Page(s): S265 - S265
  05/01/2016 Authors: Moot R; Raikar S; Fleischer L; Querrey M; Doering C; Spencer T
• Genetic engineering of chimeric antigen receptors using lamprey derived variable lymphocyte receptors.
  Mol Ther Oncolytics Volume: 3 Page(s): 16026
  01/01/2016 Authors: Moot R; Raikar SS; Fleischer L; Querrey M; Tylawsky DE; Nakahara H; Doering CB; Spencer HT
• Expanding the Ligand Binding Repertoire of Chimeric Antigen Receptors Using Lamprey Variable Lymphocyte Receptors
  Volume: 126
  12/03/2015 Authors: Moot R; Raikar S; Fleischer LC; McCarty D; Querrey M; Doering CB; Spencer HT
• Outcomes of pediatric low-grade gliomas treated with radiation therapy: a single-institution study.
  J Pediatr Hematol Oncol Volume: 36 Page(s): e366 - e370
  08/01/2014 Authors: Raikar SS; Halloran DR; Elliot M; McHugh M; Patel S; Gauvain KM
• OUTCOMES OF PEDIATRIC LOW GRADE GLIOMAS TREATED WITH RADIATION THERAPY: A SINGLE INSTITUTION STUDY
  Volume: 60 Page(s): 443 - 444
  01/01/2012 Authors: Raikar SS; Halloran D; McHugh M; Gauvain K
• The fantastic journey of a bullet: out with a snare.
  Pediatr Cardiol Volume: 31 Page(s): 108 - 110
  01/01/2010 Authors: Raikar SS; Jureidini SB; Balfour IC; Tinker K